BIOTECHNOLOGY | MEDICAL ENGINEERING | PHARMA | ANALYTICS | HEALTH

BioRegio Regensburg

LOCATION FOR SCIENCE AND QUALITY OF LIFE BioRegio Regensburg Zwickau HESSE

Frankfurt Coburg Hof Prague Karlovy Vary

Darmstadt Würzburg Bayreuth Plzen Weiden BioRegio Regensburg Nuremberg Amberg

Cham CZECH REPUBLIC Neumarkt Regensburg

Budweis Straubing Stuttgart Ingolstadt Deggendorf

Passau DANUBE Landshut BADEN- Linz WÜRTTEMBERG Ulm Augsburg BAVARIA

Munich UPPER AUSTRIA Welcome to BioPark Regensburg

­­­­­­­2 Zwickau HESSE

Frankfurt What is Biotechnology? a Cluster Region in East Bavar- Coburg Hof Prague Biotechnology deals with the use of enzymes, cells and whole ia (See map). It was once again Karlovy Vary organisms in technical application. The goal is the development of in accordance with Federal new or more efficient processes in the manufacture of wine, insulin, Initiatives BioRegio (1996), Darmstadt Würzburg Bayreuth vaccines or bioethanol and the development of diagnostic methods go-cluster (2006) and Europe- Plzen and treatments for cancer, dementia or metabolic disease. Currently an Cluster Excellence Initiative Weiden there are nearly 30 biotech companies recorded in the BioRegio (2011) awarded with the “Silver” label in 2020. Regensburg according to the OECD definition. Our Mission Amberg BioRegio Regensburg Nuremberg What are the Life Sciences? Our mission is the advancement of biotechnology, diagnostics and People understand the term life sciences as a broad field that deals analytics, medical technology and healthcare in the region. This Cham CZECH REPUBLIC with the processes or structures of living organisms or which living includes the constant expansion of the network of the BioRegio Neumarkt organisms are involved in. Aside from biology, it comprises applied Regensburg and the Technology and Start-up Centre. With the Regensburg fields such as medicine, medical technology, biochemistry, molecu- classical elements of cluster politics, business development and lar biology, biophysics, informatics or pharmacy. Currently at least location marketing, we support and promote the development of the Budweis 30 life science companies in the BioRegio Regensburg work in at life sciences in the region. As part of our public relations, we actively Straubing Deggendorf Stuttgart Ingolstadt least one of these fields. contribute to dialogue on the thematic fields on site and support young people in orientation for their future professional life. As an Passau What is interdisciplinary? enterprise of the City of Regensburg it is our goal to be in the black DANUBE Interdisciplinary means the use of approaches, ways of thinking through a balanced relationship between expansion and funding, Landshut BADEN- Linz or at least methods from different fields of study. Several location to ensure the sustainable facilitation of society through financial WÜRTTEMBERG Ulm BAVARIA analyses have identified 13 companies in the BioRegio Regensburg funding by the European Union, the German Government, the State Augsburg in the fields of mechanical engineering, textiles, metal construction, of Bavaria and the City of Regensburg. glass production and electrical en- UPPER AUSTRIA Munich gineering which have products and Our Vision developments from the life sciences Our vision is to expand the BioPark into one of field. the leading innovation centers and the Clus- ter BioRegio Regensburg into a successful What do we understand by productive network in the fields of the life the term Healthcare? sciences and healthcare. For this reason we Healthcare is a collective term for want to provide the location of Regensburg all industry branches which have to and the East Bavarian Region with a further do with health. The core sector is in- highly innovative sector of the economy with patient and out-patient care. There‑ a promising future and thereby create jobs. fore the wholesale service and the Furthermore through the promotion of the supplier sectors are grouped togeth- fascination for biotechnology, we would like er with the pharmaceutical indus - to bring this closer to the people as one of the try, bio- and medical technology and technologies for a better life and as a possi- trade of medical products. ble career goal. Through targeted advancement and consultancy to start-ups, the BioPark should be a breeding ground for young What is BioPark Regensburg? companies. With its comprehensive total concept, the BioPark BioPark Regensburg GmbH is a cluster management organization would like to provide extensive guidance to its leaseholders and and operates a Technology and Start-up Center on the grounds strategically successfully accompany them from their foundation to of the University of Regensburg. This consists currently of three having their own premises. Our companies should feel comfortable buildings totaling 18,000 m2. The BioRegio Regensburg is defined as in their location and put down roots.

More Information: www.biopark-regensburg.de

­­­­­­­3 BioRegio Regensburg

Regensburg at the head of the Danube

BioPark Regensburg GmbH is the management unit of the BioRegio Regens- burg cluster in Eastern Bavaria. The area is strategically located at the north- ernmost point of the Danube in the border triangle with Austria and the Czech Republic. Currently, 61 companies in the life sciences sector with 4,093 employ- ees are active here. This makes it the second largest biotechnology region in Bavaria after Munich.

Welcome to Regensburg The City of Regensburg which is more than 2000 years old is located at the northernmost point of the Danube about an hour’s drive from both Munich and Nuremberg. With almost 170,000 inhabit- ans, Regensburg has become the center of Eastern Bavarian conurbation with 2.5 million inhabit- ants which in past years has experienced a remarkable economic and technological upswing. And with the fall of the Iron Curtain of the earlier Western European border it has made its way back into the center of Europe.

­­­­­­4 The Business Location Regensburg Charité, there are the four large The development of innovative technologies in the City and its sur- hospitals in Regensburg: the Dis- roundings is booming. The region has become one of the strongest trict Hospital, the University Hos- growing economic regions in Bavaria. International leading high- pital, the Caritas Hospital St. Jo - tech companies such as BMW AG, Infineon AG, Continental AG or sef and the Barmherzigen Brüder Osram have located here and are expanding at this location. Strong Hospital. There is also fame and mid-sized companies such as Krones AG or Maschinenfabrik Rein- honour at the gates of Regensburg in Bad Abbach. The Asklepios hausen GmbH have been able to develop. Regensburg is booming Hospital Bad Abbach is ranked among the best hospitals through- as a healthcare city. With 2.7 billion in turnover and a total of 21,600 out Germany in this top group. In the region around Regensburg the employees, the healthcare sector has developed into an important Straubinger Hospital St. Elisabeth and the St. Marien Hospital in sector of the economy in the City and the Region. The Regensburg Amberg are listed by the Bavarian ranking. hospitals currently employ 11,718 people, including 600 local doc- tors, over 100 dentists and almost 50 pharmacists on site. Training in Regensburg In the region there are various vocational schools for the training of Medical Supply in Regensburg biological-technical, pharmaceutical, medical-technical, agricultur- Regensburg hospitals are ideally networked with the universities al-technical or chemical-technical assistants. In addition, there are and the university hospital. Regensburg hospitals are at the fore- medical vocational schools for geriatric care, occupational therapy, front, on the list of the 100 top clinics in Germany, led by the Berlin emergency paramedics, health and nursing assistance.

­­­­­­­5 BioRegio Regensburg

BioPark I BioPark II BioPark III

The BioPark Regensburg Project has been BioPark Regensburg GmbH is the management funded by the following institutions: unit of the BioRegio Regensburg cluster in Eastern Bavaria. The area is strategically located at the northernmost point of the Danube in the border triangle with Austria and the Czech Republic. Cur- City of Regensburg Bavarian State Government rently, 61 companies in the life sciences sector with 4,093 employees are active here. This makes it the second largest biotechnology region in Bavaria after Munich.

Offensive Future Bavaria The Federal Government Second Stimulus Program of Investment

European Regional The Federal Ministry for Development Fund (EFRE) Education and Research (BMBF)

­­­­­­­6 The BioPark Regensburg

In 2019, BioPark Regensburg celebrated its 20th anniversary. distric hospital and the During this time, 661 million euros, including 154 million euros in two municipal start-up venture capital, 326 million euros in equity and 180 million euros and technology centers in subsidies, have been invested in the development of the life BioPark and TechBase. sciences, 42 million euros of which in the three BioPark buildings The main areas of alone. Today, 35 companies and institutes with 718 employees are research include active here on an area of 18,000 m2. The BioPark supports start- immunology, cell up activities at the Regensburg location with special offers, such therapy, transplantation as Startup Weekend, Career Day or the personal interview. In the medicine, neurology, last 20 years, 64 life science start-up teams from Eastern Bavaria oncology and medical participated in the Northern Bavaria Business Plan Competition, technology. With the including very successful companies such as Geneart, today part of project “Healthcare the US company Thermo Fisher Scientific with 310 employees. Regensburg – managed by BioPark”, a new cluster initiative of the city of Regensburg was launched in the field of healthcare In the field of life sciences and health care, Regensburg has a lot management. In 2020, 21,600 socially insured employees worked in to offer on a campus with the university here, the East Bavarian this sector in the Regensburg region, with the industry turning over a Technical University (OTH), the university hospital, the medbo total of € 2.7 billion at the location.

­­­­­­­7 BioRegio Regensburg

Science & Business Location of Regensburg

brain-network

With the “BIOPARK8 Brain-Network there are eight successful former startups available with their comprehensive know-how on current top- Companies (Employees) ics regarding startups and business support at the location. With the ➜ BMW 9,000* “BIOPARK INNOVATION PRIZE” the BioPark supports the best appli- cation-oriented Masters, doctorates or post-doctoral theses on cam- ➜ Continental AG 8,000* pus. Furthermore the BioPark promotes the settlement of external ➜ Krones 7,000** university research institutions. In fact two working groups have been started: The Fraunhofer Institute for Toxicology and Experimental ➜ Siemens Medicine (ITEM) and the Fraunhofer Institution for Sensor Materials Infineon 6,100* (EMFT) in the BioPark. The Regensburg Center for Interventional Osram Immunology (RCI) also used the BioPark with its planned path into ➜ Maschinenfabrik the Leibniz Association. The East Bavarian Institute of Technology Reinhausen 2,000* (OTH) also started the Regensburg Center of Biomedical Engineering ➜ (RCBE) at the BioPark as the first interdisciplinary course of studies Students 33,000*** between the OTH and the Clinic at the University of Regensburg. Also the Regensburg Center of Health and Technology (RCHST) moved into * Location Regensburg ** Locations Neutraubling und Nittenau its premises at the BioPark. *** University, OTH, HfkM

­­­­­­­8 Life Science Campus Regensburg In the field of the life sciences and healthcare Regensburg together with Immunology works for example on improved treatment applications for the University of Regensburg and the Eastern Bavarian Technical Uni- cancer, infectious diseases, autoimmune disease as well as in organ versity (OTH) have somewhat to offer in matters of research. Next to the and stem cell transplantation. In the Fraunhofer Project Group for the University Hospital there is the Regional Hospital (medbo) in the imme- Diagnosis and Treatment of Tumors, Metabolic and Diseases of Ageing, diate vicinity of the campus. Additionally some of the professorships at diagnostic tests are developed to detect disseminated cancer cells the University Clinic are involved with their research and teaching close early in the development of disease and address possible metastatic to their practice in the regional hospitals, e.g. Caritas-Krankenhaus precursor cells with treatment. St. Josef. The subsidiary company at the BioPark, R-Tech GmbH, which operates the Innovation and Start-Up Center TechBase, complements Campus this with its specialties in IT and sensory technology, in particular digitalization. At the TechCampus directly nearby high tech companies ➜ 2 universities can settle next to the University Campus. In total Regensburg has ap- proximately 33,000 enrolled students and at the tertiary institutions ➜ 2 hospitals approximately 15,000 employees in research, teaching, healthcare and ➜ 2 technology centers administration. ➜ 33,000 students The strength of Regensburg lies amongst others in the fields of im - ➜ 15,000 employees munology, cell therapy and transplantation medicine. Furthermore ➜ research specialties have arisen in the fields of neurology, oncology 5,000 patients and visitors and medical technology. The RCI Regensburg Center for Interventional

EAST BAVARIAN INSTITUTE OF TECHNOLOGY

R E G E N S B U R G G

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Munich P A3 Nuremberg Exit Regensburg A3 Universität/Klinikum Motorway Intersection P Regensburg B15

Overview of the Regensburg Science Campus with University, University Hospital, Institute of Technology, Regional Hospital UNIVERSITY and the BioPark Technology and Startup Center, TechBase and HOSPITAL TechCampus

­­­­­­­9 BioRegio Regensburg

Excellent Networks

Awarded to: Cluster-Initiative in Regensburg

BioRegio Regensburg Techbase Regensburg

Bayerisches IT-Sicherheitscluster

www.biopark-regensburg.de www.mobilitylogistics.de www.sensorik-bayern.de www.it-sicherheitscluster.de

Population Regensburg Silver Cluster The European Cluster Excellence Initiative (ECCA) certifies cluster ➜ 168,876 people organizations throughout Europe. Five clusters in Upper Palatinate ➜ Prediction of population +4.5 % (2019 to 2039) were awarded silver. Four clusters are housed in the Technology ➜ Unemployment rate 3.5 % and Startup Centers of the City of Regensburg – BioPark and Tech- ➜ 2 million people in the 50km radius Base and thereby impressively document the high degree of inno- vation of the location. Excellent quality for innovative products.

Network Activities

➜ Life Sciences* ➜ Energy ➜ Healthcare ➜ Electromobility ➜ IT-Security* ➜ Culture- & Creative Industries ➜ Sensory Technology* ➜ Artificial intelligence ➜ IT-Logistics* ➜ GreenTech ➜ Mechatronics & Automation * certified with SILVER in accordance with the European Cluster Excellence Initiative

­­­­­­1 0 Moscow Warsaw Prague Kiev Montréal Vienna Budapest Zurich Bucharest San Francisco Zagreb Sofia New York Istanbul Tokyo Tel Aviv Qingdao Cairo Chengdu Shenzhen Mexico Riad Abu Dhabi

Bangalore Ho Chi Minh City Bogota

Lima

São Paulo Johannesburg Santiago de Chile Buenos Aires

Bavaria´s Foreign Representations Biotech start-up centers in Bavaria

www.igz.wuerzburg.de Competence für International Business

www.medical-valley-center.de www.invest-in-bavaria.com www.bayern-international.de Bayreuth Würzburg Erlangen www.biopark-regensburg.de Nuremberg Production in the Region A range of companies at BioRegio Regensburg have developed into Regensburg Straubing international production locations for clean rooms. These include www.izb-online.de pharmaceutical companies such as Bionorica SE (Neumarkt) and Freising Haupt Pharma Amareg GmbH, part of Aenova group (Regensburg), and Munich www.straubing-sand.de/biocampus also biotechnology companies such as Syntacoll GmbH (Kelheim) and Martinsried PAN Biotech GmbH (Aidenbach) as well as medical technology com- panies such as RKT Roding Kunststoff-Technik GmbH, Raumedic AG (Helmbrechts) and Gerresheimer GmbH (Pfreimd). In the additive manufacturing of medical products FIT Production GmbH (Lupburg) is found throughout the world in a leading role. www.biotech-bayern.de

­­­­­­­1 1 BioRegio Regensburg

HealthCare Regensburg

Healthcare Regensburg Initiative At the beginning of 2017 the BioPark brought the new brand name In 2020, 21,600 employees with social security insurance worked in the “Healthcare Regensburg” to life to be able to do justice to the collecti- healthcare field. 80% of these are in the City of Regensburg and 20% in ve visibility of the health location in keeping with the wishes of all the the Regensburg District. stakeholders. In doing so the Bioregion Regensburg Cluster is being Since the start of 2020 the “Healthcare Regensburg Initiative” is being further developed and the content around the thematic field of health- funded for a total of three years by the Ministry of Economy, Develop- care economy is being expanded. A masterplan was produced also ment and Energy. The goal is to establish a regional network in the from which the first recommendations for action and project proposals healthcare industry and thereby together with the network partners for the further development of the healthcare economy at the Regens- develop and put into action concrete measures and projects. These burg location and in the region proceeded. The project was funded for are thereby oriented by the broad thematic fields decided upon in the three years by the State of Bavaria. masterplan: • network activities and knowledge transfer The growing significance of this industry for the future of Regensburg • digitalization of healthcare region is also expressed in numbers. Between 2011 and 2020 the num- • aging society and demographic change ber of employees in the healthcare industry has risen by around 34%. • securing specialty staff and training and further education.

Hospitals Results of the 2021 Study

➜ 5 hospitals The number of employees with social security insurance in the health industry ➜ 2,850 beds in the Regensburg Region rose from 2011 to 2020 by ~34% ➜ 10,000 employees 8,674 Hospitals +35% ➜ 120,000 patients p.a. 11,715a

Local doctors and 2,955 +38% dentists field 4,087

Source: © Statistics Pharmacies, 1,438b from the Federal Agency +17%b for Employment; data remedies & aids 1,675c for June 2011 and June 2020. Inpatient and 3,078 outpatient care +34% of the elderly 4,123

a Figure for Regensburg district approximated, as not given for data protection reasons. | b Figure for remedies & aids from 2011 Study, as not available from SBfA for data protection reasons. | c Figure for remedies & aids for Regensburg district approximated, as not given for data protection reasons; limited comparability.

­­­­­­1 2 Healthcare Regensburg

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HOSPITAL OF THE ORDER Donau OF ST. JOHN OF GOD Hof REGENSBURG Danube Cathedral A93 15 ße ger Stra Prüfenin Old Town

HANS BAUER 8 ZWISCHENWELTEN CARITAS- Central Station HOSPITAL Kultur im Krankenhaus Friedenstraße ST. JOSEF

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Interdisciplinary Projects In the past the BioPark has already put several Number of employees with social security insurance successful projects into action. With the project “IA-BIOTECH” regional interdisciplinary fields in the region have been linked. In the fields of ap- +33.8% plication of molecular diagnostics and biochips as well as biofunctional surfaces, regional com- panies from the glass industry, civil engineer- ing, electrical engineering, textiles and nutrition have been brought together with the companies from BioRegio Regensburg. Thanks to this new cross-technology network, the dynamics in the cluster could be increased by a further 13 region- al companies. Another approach is the sensor 16,145 21,600 technology cluster platform of the Allianz Bay- ern Innovativ initiative, which is controlled from 2011 2020 Regensburg.

­­­­­­­1 3 Successful at the BioPark:

BIOPARK PROJECTS AND THEIR TRADEMARKS

BioPark Regensburg: Since 1999 Healthcare: Since 2016 location analysis and startup and technology center and project on the expansion of the cluster in the BioPark Jump: Since 2018 cluster initiative in the field of life field of healthcare. Specialties to date: cell office set up for consultancy sciences in East Bavaria (BioRegio therapy and oncology, digitalization, e-health, as accelerator for the goal- Regensburg). 18,000 m2, 61 companies, telemedicine and medical engineering, ageing oriented cooperation of users 4,093 employees. Biotechnology, society, specialists and training, location and developers at the Biopark. pharma, medical engineering, marketing and promotion of the economy as analytics and diagnostic industries. well as innovation and startups.

brain-network

Brain8-Network: Since 2014 expert network for startups, acquisition of funding, financing, development Innovationspreis: Since 2015 and strategy for companies, markets Interdisziplinaritäts-Agentur BIOTECH: competition for outstanding and internationalization, licensing Since 2007 location analysis, project and innovative and application-related processes, patent and contract law concept on the interdisciplinary expansion of ideas at regional university and as well as company takeover and the cluster in the paper, metal, plastics, glass external university research integration processes. and foodstuff industries. institutions in Regensburg from the health and life sciences fields.

bamBIOni: Since 2011 BioPark Regensburg has had its own child daycare for all the employees. Care is provided by St. Johns crèches. gefördert durch BioPark Regensburg

­­­­­­­1 4 In 2020 the number of companies at BioRegio Regensburg increases to 61, the number of employees to 4,093

65 Development of Life Science industry and employees from 2006 – 2020 61 58 55 4.500 55 51 50 51 47 48 48 4.000 45 45 42 44 3.500 39 40 40 3.000 35 2.500 25 2.000 1.500 15 number of employees

number of companies 1.000 5 500 start-up 0 insolvency – 5 – 1 – 0 – 1 0 – 2 0 – 1 – 2 – 1 0 – 1 0 0 0 0 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020

start-up (without accesses) insolvency (without departures) total no. of enterprises total no. employees

Source: BioPark Regensburg GmbH 2020

BENCHMARK DATA ON BIOPARK REGENSBURG (STATUS 2020)

Construction costs for the three BioPark buildings ➜ Total 41.1 million euro ➜ Thereof BioPark I (completion 2001) 13.8 million euro ➜ Thereof BioPark II (completion 2006) 12.8 million euro ➜ Thereof BioPark III (completion 2011) 14.5 million euro

Thereof funding by ➜ State of Bavaria 20.6 million euro ➜ Federal Government (Stimulus Program II) 9.7 million euro ➜ City of Regensburg 5.6 million euro ➜ Equity Capital BioPark GmbH 4.3 million euro ➜ EU (EFRE funding) 0.9 million euro

Gross area at the BioPark 18,000 m2 ➜ Thereof gross surface area for the leaseholders 17,300 sqm ➜ Thereof laboratories (S1/S2) 4,959 sqm Number of leaseholders at the BioPark 35 718 employees

➜ Thereof companies 20 483 employees ➜ Thereof research institutes 11 206 employees ➜ Thereof service providers 4 29 employees Number of start-ups at the BioPark since 1999 65 The Biotech Companies despite ➜ Number of the external companies settled at the BioPark 26 hard times have gone against ➜ Number of successful companies moved out of the BioPark 15 the general trend: their number has remained stable, whilst the ➜ Number of company closures at the BioPark 16 number of employees has actu- ➜ Number of insolvencies at the BioPark 5 ally significantly increased.

­­­­­­­1 5 BioRegio Regensburg (Updated 5/2021)

Companies of the BioRegio Regensburg

Biotech-Companies by OECD

2bind GmbH compatible fluoro­phores and fluorescence- Artract Medical UG (in the BioPark, founded in 2011, conjugated molecules. (in the BioPark, founded in 2018, 10 employees) offers customers from 4 employee) is developing a fully pharma and biotech various biophysical AKTORmed GmbH implantable circulatory assist device for analytical services. Our customers benefit (founded 2005, 16 employees) is the patients suffering from Heart Failure with from a strong expertise in biophysical German market leader for robot-supported preserved Ejection Fraction (HFpEF). methods, from customized milestone based assistance systems, which enable perfect projects with clear timelines and reliable imaging during procedures in minimally Assay.Works GmbH cost structures. invasive surgery. (in the BioPark, founded in 2016, 7 employees) Contract research AARU Audi Accident Research Unit aquagroup AG organization, developing and executing (in the BioPark since 1999, 16 employees) (founded in 2004, 22 employees) ensures tailor-made and scalable assays for With the joint goal of reducing the risk of a supply of germ-free drinking water right bioactivity quantification in pharmaceutical, injuries and its consequences, AUDI AG and at the location of use and offers holistic biotech and academic research. the department of casualty surgery at the hygiene concepts. University of Regensburg have joined forces bava medical Pharma GmbH in a research project called AARU (AUDI AR Medical Writing (founded 2018, 1 employee) specializes in ACCIDENT RESEARCH UNIT). (founded in 2020, 1 employee) is a freelance the import and distribution of high-quality consultancy that offers expert medical and medical cannabis products. Furthermore Active Motif GmbH scientific writing services in a broad range the company works on the development (in the BioPark, founded in 2005, of disciplines to partners in the pharma and of special forms of administration and the 2 employees) develops and produces biotech industries and in academia. creation of healthcare provision fluorescent dyes, nanoparticles, LED networks.

­­­­­­­1 6 BioGents AG (founded in 2002, 33 employees) develops biological attractants and repellents for pest insects. Involves the research and development of monitoring systems. Molecular biological analysis.

Biometric GmbH (founded in 1996, 16 employees) is a laboratory for microbiological and chemical analysis – dealing with the analysis of water, hygienic control and providing micro­bio­ logical analyses of pharmaceutical products, medical devices, cosmetics and food.

Bionorica SE Cfm Oskar Tropitzsch GmbH of diagnostic methods and cell bases (founded in 1933, over 1,800 employees) (founded in 1985, 9 employees) is diagnostic methods. develops and produces drugs from plants specialized in rare chemicals and the under GMP-conditions (phytotherapeutics). contract manufacturing according to Delphitest GmbH Subsidiary Bionorica Ethics GmbH (former customers needs. Core areas of activity are (founded in 2004, 4 employees) works on Delta 9 Pharma GmbH, founded in 2002) fermentation products, phytochemicals, DNA diagnostics and focuses on paternity develops new active substances and pharmaceutical raw materials, enzymes, tests and other genetic analyses for private medicines in the field of pain relief. venoms, metals and metal salt dilutions. customers.

BioVariance GmbH CRITEX GmbH Delta Entwicklungsgesellschaft GmbH (founded in 2013, 18 employees) offers (founded in 2000, 25 employees) is an (founded in 1994, 2 employees) works in complex biomedical data analyzes to IT consulting and software development development projects on a contracting customers from the pharmaceutical and organization. As part of CRITEX, MedITEX basis for manufacturers of tables for patient biotechnology sector as well as to the specializes in medical software solutions. positioning and technique equipment health care sector. BioVariance GmbH also manufacturers in Germany and abroad develops customized software solutions for danumed Medizintechnik GmbH (Medical Engineering). these industries. (founded in 2017, 7 employees) develops, manufactures and distributes a wide range DRACOON GmbH brainjo | Fitness-Studio fürs Gehirn of innovative and high-quality medical (founded in 2008, 65 employees) market (founded in 2018, 5 employees) arose from products for enteral nutrition. leader for Enterprise Filesharing in German- an initiative with the purpose of helping speaking countries. The software provides people with a weakness in concentration. Davids Biotechnologie GmbH an integrated encoding system controlled The team had recognized that in lifestyle (founded in 1996, 11 employees) production by the client and is available as cloud, environments (fitness studios, offers of polyclonal antibodies (in both chicken hybrid and on-premise versions. It provides in company healthcare management egg yolk and rabbits), development of a wealth of options for securely exchanging and sports institutions) there are no monoclonal antibodies, production and medical history, lab data or patient cost-attractive solutions for sustainable purification of antibodies from cell cultures information. individual brain training. and bioreactors. Transient transfection of cells in cell cultures and purification ESy-Labs-GmbH CASCAT GmbH of the produced proteins. Development (founded in 2018, 4 employees) as a (founded in 2014, 6 employees) deals with the chemo-enzymatic conversion of biomass into basic and fine chemicals.

More Information: www.biopark-regensburg.de

­­­­­­­1 7 BioRegio Regensburg

representative of electrocatalysis in FUTUR provider in the field of development and electroorganic and electroinorganic (in the BioPark since 2001, optimisation of ready-for-the-market synthesis is a leading company in the field 6 employees) FUTUR (Forschungs- products e.g. bone cement based on nano of electrifying chemical processes. und Technologietransfer Universität silver for inflection prophylaxis. Legal Regensburg) is Regensburg University’s successor of rent a scientist GmbH (founded Evanium Healthcare GmbH multidisciplinary service facility for in 1995) and ras materials GmbH (founded (at the BioPark, founded in 2017, knowledge and technology transfer. It is a in 2010). 3 employees) develops food products to link between private business and university promote dietary health in the life science research. Hyperthermics Regensburg GmbH field. (founded in 2008, 6 employees) works on Gerresheimer Regensburg GmbH commercial application of hyperthermophile FIT Production GmbH (founded in 1948, 350 employees in medical microorganisms, screening and culturing of (founded in 1995, 21 employees in medical technology in Bavaria) a leading company all kinds of hyperthermophiles for industrial technology) is a company of the FIT in the business fields of tubular glass, applications. Additive Manufacturing Group and has moulded glass, life science research and specialized in additive engineering, serial plastic systems. Inotech Kunststoff GmbH production, mass customization and single (founded in 1986, 18 employees in medical part manufacturing in industries such as Gramm UG technology). Manufacturer of technical automotive and motorsports, aviation and (founded in 2017, 2 employees) is a injection moulded plastic parts, e.g. for aerospace, mechanical engineering and specialist for customized orthopaedic medical technology, pharmaceutical and medical technology. implants and surgical guides. cosmetics industries. Designs and creates prototypes for industry and research Fraunhofer ITEM Haupt Pharma Amareg GmbH (3D-printing). (in the BioPark since 2006, 43 employees) (founded in 2003, 422 employees) Focus Currently, one in four deaths is caused by on pharma­ceutical contract manufacturing Institute of Functional Genomics cancer – mainly as a result of metastatic (GMP production, packaging of solid (in the BioPark since 2006, 21 employees) disease spread. Thus, the Project Group enzyme products, liquid and semi-solid Systems biology of malignant and non- concentrates on the development of medicines). Part of aenova group since malignant diseases; Development of diagnostic tests to detect disseminated 2014. analytical tools for the high-throughput cancer cells early in the disease and systematic characterization of genomes, to predict the response to therapy of HeiQ RAS AG transcriptomes, proteomes and metastatic progenitor cells. (founded in 2016, 26 employees) Service metabolomes of cells, tissues and biofluids;

­­­­­­1 8 Structural, functional and comparative our company’s focus remains Peptide for hygiene products, specialty papers, genomics. Chemistry, while we also have strong filtration, technical textiles, flock and many expertise in Drug Delivery, Life Sciences other applications. IQ MEDWORKS GmbH and Custom Syntheses. Our mission is to (founded 2012, 4 employees) develops accompany our customers in their current KFB Kompetenzzentrum telemedical systems, inter alia, for more projects by supplying the most novel Fluoreszente Bioanalytik efficient care of patients in outpatient substances and latest technologies. (in the BioPark since 2000, 4 employees) care or emergency medical service. The Recent advances in Microarray and Deep establishment of regional coordination Iris Biotech Laboratories GmbH Sequencing Technologies fundamentally centers should support this. (founded in 2013 by Iris Biotech GmbH, changed the face of modern life sciences. 5 employees) is a chemical laboratory with Within this vibrant and constantly growing Iris Biotech GmbH specific know- how in synthesizing chiral market, KFB - Center of Excellence for (founded in 2001, 22 employees) approx. compounds, hydrophilic polymers and other Fluorescent Bioanalytics - has established 6500 products, provides scientists in both fine chemicals. The majority of the work is itself as a competent service provider industry and academia with innovative and contract research, process development and offering customer-oriented research and rare compounds, while also being your custom synthesis. development solutions. reliable partner for a comprehensive supply of standard consumables. Guided by our Kelheim Fibres GmbH Labor Friedle GmbH dedication to deliver competent service as (founded in 1935, 500 employees) world (founded in 2003, 90 employees) Certified well as the highest quality to our customers, leading producer of viscose specialty fibres chemical-analytical laboratory for food ingredients, analytics of chemical residues, nutrient content analytic, examination of human biological matrices, microbiological examinations and examination of indoor air pollution.

Labor für Experimentelle Unfallchirurgie (Klinik und Poliklinik für Unfallchirurgie) (in the BioPark since 2017, 15 employees) The Laboratory of Experimental Trauma Surgery investigates the basics and coherence of joint diseases and connective tissues.

Cluster-Manager BioRegio / HealthCare Regensburg, f.l.t.r.: Dr. Thomas Diefenthal, Dr. Ilja Hagen

More Information: www.biopark-regensburg.de

­­­­­­­1 9 BioRegio Regensburg

LI-EX GmbH for the execution and electronic nal von minden GmbH (founded 2005, 9 employees) is the industry documentation of clinical studies. (founded in 2004, 100 employees) leader in tailor-made LED applications specialized in rapid tests, Elisa and and since 2020 additional novel products Medical Device Partners GmbH homogenous enzyme immune assays in the with UV-C light for disinfection are being (founded in 2001, 2 employees) is a fields of gynaecology, infectious diseases, developed. consultancy with the aim to support their cardiac infarct markers, detection of cancer, clients in bringing products and services urology and especially drugs of abuse. lifespin GmbH successfully to the medical device market. (in the BioPark, founded 2017, NeuroProfile GmbH 16 employees) develops analytical methods Microbify GmbH (founded in 2001, 2 employees) develops and software solutions that generate (founded in 2021, 4 employees) experts in novel pharmaceuticals for diseases like digital metabolic images from human or anaerobic microorganisms. Microbify is a Parkinson’s, Alzheimer’s, schizophrenia and biological samples. These are used for service provider in the areas of biological depression by using innovative neuronal targeted substance quantification in a multi- methanation (power-to-gas), microbially targets (disease-related genes or proteins). parameter set up, for metabolomics studies induced corrosion (MIC) and the cultivation and classification algorithms, including the of anaerobic bacteria and archaea. numares HEALTH integration of big data approaches. (in the BioPark, founded in 2004, 54 Mikrogen GmbH employees) develops and markets Lisando GmbH (located in BioPark, formerly Lophius integrated test systems for human (in the BioPark, founded in 2009, Biosciences GmbH, founded in 2002, diagnostics. The fully automated numares 16 employees) designs and develops 18 employees) develops T-cell-based systems provide information about novel effective antibacterials to combat diagnostic tests for targeted diagnosis and formation, extent and severity of diseases bacterial pathogens e.g. proteins that are personalized management of patients in the in high throughput operations. They ensure designed by LISANDO in order to efficiently fields of transplantation, and of infectious improved treatment options at high patient destroy bacteria, using an enzymatic and autoimmune safety and cost-effectiveness. mechanism. diseases. Oxford BioLabs Deutschland GmbH MaganaMed GmbH Multi-Service-Monitoring (in the BioPark, founded in 2009, (founded in 2017, 2 employees) develops (founded in 2003, 2 employees) offers 1 employee) is a science-based company and distributes SaaS solutions for the services for the conduct of clinical studies tackling Androgenetic Alopecia (AGA), medical sector throughout Europe. The in Germany, Austria, Switzerland, Czech which is commonly known as male and Magana Trial Manager is used successfully Republic, Slovak Republic and Hungary. female pattern baldness. The company

­­­­­­2 0 is developing novel effective health and with experience of over 20 years in for customers in Biotechnology, Pharmacy, beauty therapies to help people stay young the manufacturing of preservative- Medical Devices, Food Industry and in many and healthy longer and to extend their free eye drops in single dose units. other scientific fields. quality of life. Contract manufacturing for international pharmaceutical industry. Prima Medical Technologies GmbH PAN-Biotech GmbH (in the BioPark, founded in 2018, (founded in 1988, 43 employees) partner PolyQuant GmbH 2 employees) is a medical device company in the field of cell-culture, especially for (founded 2007, developing innovative medical devices that serum-free systems, cell culture media, 10 employees) provides products, address a high medical need and have a custom-made products and research. services and supporting bioinformatics significant positive impact on patient´s Application-oriented product optimisation. for proteomics. PolyQuant also offers lives. Our business approach is designed to calibration standards for HPLC and mass reduce clinical and financial risks early and PAN-Seratech GmbH spectrometry as well as customized create value quickly. (founded in 2016, Subsidiary of PAN Biotech solutions for quantitative proteomics, GmbH, 15 employees) develops, produces particularly applicable for biomarker Quimedo GmbH and markets biotechnological products all research. (founded 2020, 6 employees) is a social around cell culture. network for healthcare which facilitates care PreSens Precision Sensing GmbH providers in networking quickly and simply. Pharma Stulln GmbH (in the BioPark, founded in 1997, (founded in 1984, 270 employess) 106 employees) developer and manufacturer Raumedic AG produces sterile pharmaceutical products of chemical optical sensors and systems (founded in 2004, 650 employees) supplier for medical and pharmaceutical companies. Development and production of innovative diagnostic and acute therapeutic systems for the sectors of neurosurgery, urology, gastroenterology and traumatology.

RCHST Regensburg Center of Health Sciences and Technology (in the BioPark since 2018, 19 employees) The “Regensburg Center of Health Sciences and Technology” (RCHST) is an inter-faculty research institute at the Ostbayerische Technische Hochschule Regensburg (OTH Regensburg), which is substantially supported by the Bavarian State Government.

Managing Directors BioPark, f.l.t.r.: Prof. Dr. Georg Barfuß (CFO), Dr. Thomas Diefenthal (CEO)

More Information: www.biopark-regensburg.de

­­­­­­­2 1 BioRegio Regensburg

RCI Regensburg Center SCHOTT AG Telexos GmbH for Interventional Immunology Site Mitterteich(founded in 1970, former (at the BioPark since 2019, 3 employees) (founded 2010, 16 employees) The RCI SCHOTT-Rohrglas GmbH, 1000 employees) develops products for the personalized Regensburg Center for Interventional products and services for international diagnosis of cancer on the basis of blood Immunology was established in 2010 as growth markets such as pharmaceutics, samples (liquid biopsy). Telexos is planning a central unit of Regensburg University electronics, automotive and environmental to introduce its first products in 2021 and in order to tie all academic research technology. will market these themselves. areas related to the development of new immunotherapies. Semiflow Medical UG Thermo Fisher Scientific GENEART GmbH (in the BioPark, founded in 2018, 1 employee) (at BioPark, founded in 1999, relyon plasma GmbH is developing an endovascular stent that 310 employees) service provider for gene (founded in 2002, 20 employees) develops replaces deficient vein valves in the legs to synthesis and downstream processes (DNA products for the plasma treatment for treat Chronic Venous Insufficiency. engineering and processing). Provides industrial and medical applications, as well Synthetic Biology for customers of Pharma- as process solutions for surface cleaning Strategische Partnerschaft and Biotech-industry. Since 2014 GeneArt and activation. Sensorik e.V. – Intelligent Sensor belongs to the US-based Thermo Fisher Systems made in Bavaria Scientific Inc. RKT Rodinger Kunststoff Technik GmbH (founded in 2007, 18 employees) The (founded in 1974, 56 employees in medical “Strategic Partnership for Sensor TriOptoTec GmbH technology) develops plastic components Technologies” (SPS) is a network with (in the BioPark, founded in 2010, for medical technology engineering, for its focus on research and development 28 employees) works in the area example biosensors and different pharma/ in the field of sensor technologies. It of photodynamic disinfection and medical applications. works, amongst other projects, on optical decontamination. technologies in photodynamics, food safety Schmack Biogas Service GmbH and sterilization. Tumorcenter Regensburg (founded in 1995, 164 employees) (in the BioPark since 1999, 35 employees) technology and market leader of the Syntacoll GmbH The tumor center is a health insurance German biogas industry. Planning, (founded in 1927, 99 employees) develops funded non-profit organisation for data construction and operation of ready-to- and manufactures innovative collagen transfer, continuous education and use peripheral biogas plants. Part of the products for medical and pharmaceutical improvement of medical processes, Viessmann Group since 2010 use (implants and tissue engineering). for example therapy evaluation,

­­­­­­2 2 CONTACT implementations of new therapy strategies BioPark Regensburg GmbH in cancer care. Am BioPark 13 / BioPark III D-93053 Regensburg, Germany Velvio GmbH Phone: + 49 (0)941 92046-0 (in the BioPark, founded in 2019, Fax: + 49 (0)941 92046-24 2 employees) The company Velvio develops new compounds to restore organ repair [email protected] functions as new treatment option. www.biopark-regensburg.de Dr. Thomas Diefentahl Dr. Ilja Hagen CEO Project Manager Venock Medical UG Healthcare Regensburg (im BioPark, founded in 2018, 2 employees) is developing an automatic closure system for large bore punctures in veins following interventional catheter-based therapies. IMPRINT WK IT GmbH Publisher: BioPark Regensburg GmbH (founded 1987, 80 employees) offers Editorial staff: Dr. Thomas Diefenthal customized IT solutions. Their strategy Conception / Design: optimizes digitization processes and bauer.com communication & marketing gmbh, www.bauercom.eu enables the planning and implementation Images: BioPark Regensburg GmbH; foto art Elisabeth of efficient and individual Wiesner; bauercom.eu; fotolia.com – © Alex (1), software for each pressmaster (3, 8), Hoda Bogdan (10), customer. REDPIXEL (10), spotmatikphoto (12), upixa (18); AdobeStock – © vegefox.com (11), Milles Studio (12)

More Information: www.biopark-regensburg.de

­­­­­­­2 3 WACHSTUMFAKTORGROWTH FACTOR & &JOB JOBMOTOR MOTOR

The Top Region RESEARCH 2 Universities I Cell therapy for excellence in science and Immunology I Oncology innovative companies:

DEVELOPMENT 50 Companies I Biotech Medtech I Health IT

Profit from the Healthcare Network HEALTHCARE with over 50 companies, Over 20,000 employees 2.7 billion Euro turnover five hospitals and two universities.

MAIN FOCUS Digitalization & AI I Innovation in Nursing Hygiene and Infection Prevention

BioPark Regensburg GmbH | Am BioPark 13 | D-93053 Regensburg | Phone: +49 941 92046-0 | www.biopark-regensburg.de