Audion Therapeutics BV is a private Dutch biopharmaceutical company dedicated to the discovery, and development of drugs and delivery technologies for the treatment of diseases affecting the ear, including hearing loss associated with aging, and exposure to excessive noise.. We are committed to discovering effective therapies through our research into inner ear cellular biology, as well as through partnerships with other companies and academic groups.

Audion has the following vacancy for its subsidiary in Cambridge, MA, USA:

Scientist in vitro pharmacology/cochlear cell biology

The position offers the possibility to join a small but unique company in an exciting emerging field of medicine.

You have a Ph.D. or MSc degree and a minimum of 3 years working (postdoctoral) experience in a biotech company or academic research group. We are particularly interested in candidates that have studied the activity of small molecules using cellular phenotypic assays including organ cultures based on primary animal or human tissues.

For academic cell biologists wanting to make a career switch to the biotech industry: we are interested to hear from scientists with a background in developmental biology or regenerative medicine, in particular those that have worked on inner ear development, drug discovery or gene therapy as evidenced by their publications.

The incumbent will be responsible for in vitro pharmacology studies using cellular assays run with neurospheres and cochlear explants generated from primary animal tissues with QPCR and imaging as assay readouts.

The incumbent will be involved in Audion’s workplan that is part of the EU FP7 Otostem consortium (www.otostem.org) and Audion’s second small molecule drug discovery program aimed at hair cell regeneration by targeting Atoh1.

Audion’s lead Notch program is planned to go into development in the second quarter of 2014 in collaboration with Eli Lilly an Audion shareholder.

Requirements

• At a minimum you have extensive hands-on experience with: o General in vitro pharmacology and molecular biology experience o Animal and/or human primary cell and tissue cultures for example human or mouse embryonic stem cells, neuronal and explant cultures o QPCR, reporter and image based readouts for measuring cellular phenotypes • You are systematic and accurate in your experiments and documentation • You understand the importance of proper documentation for the protection of intellectual property • You excel in an environment where team spirit and a result driven mentality are the norm and important to be successfull • You are experienced with project management • You are independent yet an effective, proactive communicator including the presentation of data • You are fluent in English

He or she should be able to start soon, initially it will be a 2 year appointment.

Only applicants that can proof they can legally work in the US are invited to apply.

We do not accept speculative enquiries from recruitment agencies and do not respond to unsolicited approaches by such agencies.

Interested candidates can send their CV with a cover letter to:

Helmuth H.G. van Es, Ph.D. Director R & D, co-founder At e-mail: [email protected]