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Biochemistry, Molecular and Cellular Biology University of New Hampshire 1 BIOCHEMISTRY, MOLECULAR https://colsa.unh.edu/molecular-cellular-biomedical-sciences AND CELLULAR BIOLOGY Programs (BMCB) • Biochemistry, Molecular and Cellular Biology Major (B.S.) • Biochemistry, Molecular and Cellular Biology Minor The field of biochemistry, molecular and cellular biology (BMCB) encompasses a wide range of life sciences, from biophysics and Courses biochemistry to applied biology and medicine. The B.S. in biochemistry, molecular and cellular biology is designed for students to gain a solid foundation in biology, chemistry, physics, and mathematics, along with Biochemistry, Molecular & Cellular advanced knowledge in molecular biology, biochemistry, cell biology, and genetics. BMCB students have plenty of exposure to cutting-edge Biology (BMCB) techniques and frontier research topics through inquiry-based learning BMCB 401 - Professional Perspectives in Biochemistry, Molecular and and hands-on research opportunities. The program offers research Cellular Biology opportunities with program faculty in the areas of structural biology, Credits: 1 cell signaling pathways, cancer biology, gene regulation, neurobiology, Introduction to the fields of biochemistry, molecular and cellular biology. cellular structure and function, proteomics, glycomics, and lipid Explores professional opportunities for BMCB majors. Guest speakers metabolism. Graduates are "profession-ready" and well-prepared for from on- and off-campus present seminars and lead discussions on entry-level positions in biomedical research or in the biotechnology contemporary issues in subject area. Development of strategies for and pharmaceutical industries, for graduate education, or for post- achieving professional goals. Cr/F. baccalaureate professional programs (e.g., medical school, veterinary Grade Mode: Credit/Fail school, dental school, etc.). BMCB #405 - Biotechnology Research Internship Credits: 2 The curriculum provides most of the required and recommended courses A 4-week (minimum) experiential learning internship in which students for students seeking admission to graduate schools and to professional conduct independent laboratory-based research in an area of shared schools in medicine, dentistry, veterinary medicine, or pharmacy. interest with a faculty mentor in the College of Life Sciences and Students obtaining a B.S. in BMCB enjoy excellent job prospects Agriculture. Students gain first-hand experience conducting original immediately upon graduation, due to high demand for skilled research research, incorporating direct observation, reflection, evaluation, and technicians in biotech and pharmaceutical companies, government discussion. Permission required. Open to high school students only. agencies, academic research laboratories, and medical diagnostic Grade Mode: Credit/Fail laboratories. Graduates also have knowledge and skills that are valuable in the fields of management, sales, marketing, regulatory affairs, technical BMCB 501 - Biological Chemistry writing, and science journalism. Students who major in BMCB can also Credits: 4 use their training in conjunction with advanced degrees in law and Survey of the molecular basis of life with a focus on the mechanisms of business. With additional courses in education, the B.S. degree in BMCB biochemical reactions in metabolic pathways, beginning with an overview also qualifies graduates to teach at the elementary, junior high, or high of functional groups and organic reactions relevant for living organisms. school levels. Bioenergetics of carbohydrate, lipid, and nitrogen metabolic pathways. Prereq: CHEM 403 and CHEM 404, or CHEM 411. Faculty participating in the BMCB major combine a passion for teaching Mutual Exclusion: No credit for students who have taken BMCB 658, and student advising with strong expertise and achievements in their BMCB 751, BMCB 752. research areas. BMCB faculty are committed to providing independent Grade Mode: Letter Grade research experiences for undergraduate students, and most faculty BMCB 605 - Principles of Cell Biology have active and well-funded research programs utilizing state-of-the- Credits: 4 art techniques and instruments. On-campus facilities that students can Cell and developmental biology of multicellular eukaryotic organisms. use to enhance their research experience include the Hubbard Center for Structure and function of major cellular compartments; mechanisms Genome Studies, the University Instrumentation Center, and the Center of of cellular communication and dynamics; embryonic development. Integrated Biomedical and Bioengineering Research. Special topics: subcellular organization and function; membrane biogenesis; signal transduction; mitogenesis; apoptosis; autophagy; Pre-Professional Health Programs tumor suppressors and cell cycle regulation; cytokinesis; cytoskeletal Students interested in postgraduate education in healthcare occupations dynamics; cellular shape and motility; stem cell biology; organogenesis; (e.g., medical, dental, physician assistant, pharmacy, etc.) should visit morphogenesis and patterning. Prereq: BIOL 411 and BIOL 412; the UNH Pre-Professional Health Programs Advising Office website or CHEM 403 and CHEM 404. in person (Rudman Hall, Room G02). Students interested in veterinary Equivalent(s): BIOL 605, BSCI 735 medicine should consult the Pre-Veterinary Medicine Program. While Grade Mode: Letter Grade many of the prerequisite courses required by professional schools are also requirements of the BMCB major, students should consult with their faculty adviser to create a plan of study that best prepares them for pursuing a career in one of these health professions. 2 Biochemistry, Molecular and Cellular Biology (BMCB) BMCB 658 - General Biochemistry BMCB 752 - Principles of Biochemistry Credits: 3 Credits: 4 Comprehensive, introductory course emphasizing the cellular metabolism In-depth survey of biochemistry: metabolism of amino acids, nucleotides, and the structure and function of proteins, nucleic acids, carbohydrates, carbohydrates and lipids; synthesis and regulation of macromolecules; and lipids. Prereq: BIOL 411; CHEM 545 and CHEM 546, or CHEM 547 and molecular biology of the eukaryotic cell. Prereq: BMCB 751 or permission. CHEM 548, or CHEM 651 and CHEM 652. Equivalent(s): BCHM 752 Co-requisite: BMCB 659 Mutual Exclusion: No credit for students who have taken BMCB 501. Mutual Exclusion: No credit for students who have taken BMCB 501. Grade Mode: Letter Grade Grade Mode: Letter Grade BMCB 753 - Cell Culture BMCB 658A - General Biochemistry Credits: 5 Credits: 3 Principles and technical skills fundamental to the culture of animal and Comprehensive, introductory course emphasizing the cellular metabolism plant cells, tissues, and organs. Introduction to the techniques of sub- and the structure and function of proteins, nucleic acids, carbohydrates, culturing, establishing primary cultures, karyotyping, serum testing, and lipids. This course is intended for programs that do not require a cloning, growth curves, cryopreservation, hybridoma formation and biochemistry laboratory. Prereq: BIOL 411; CHEM 545 and CHEM 546, or monoclonal antibody production, and organ cultures. Application of cell CHEM 547 and CHEM 548, or CHEM 651 and CHEM 652. culture to contemporary research in the biological sciences. Prereq: Equivalent(s): BMCB 658 BMS 503 and 504. Special fee. Lab. Grade Mode: Letter Grade Equivalent(s): ANSC 751, MICR 751, PBIO 751 BMCB 659 - General Biochemistry Lab Grade Mode: Letter Grade Credits: 2 BMCB 754 - Molecular Biology Research Methods Structured laboratory experiments that provide training in analytical Credits: 5 and preparative techniques fundamental to modern biochemistry and Theory and application of current technologies to manipulate DNA. molecular biology. Coreq: BMCB 658. Special fee. Hands-on research experience that includes DNA isolation and Co-requisite: BMCB 658 quantitation methods, cloning, PCR, DNA sequencing, and analysis of Equivalent(s): BCHM 659, BMCB 659W gene products. Prereq: GEN 604. Special fee. Lab. Writing intensive. Grade Mode: Letter Grade Attributes: Writing Intensive Course BMCB 659W - General Biochemistry Lab Equivalent(s): BCHM 754, BSCI 765, GEN 754, PBIO 754 Credits: 2 Grade Mode: Letter Grade Structured laboratory experiments that provide training in analytical BMCB 755 - Laboratory in Biochemistry and Molecular Biology and preparative techniques fundamental to modern biochemistry and Credits: 5 molecular biology. Coreq: BMCB 658. Special fee. UNHM only. Writing Application of modern techniques to the characterization and purification intensive. of biomolecules, with an emphasis on proteins and nucleic acids. Co-requisite: BMCB 658 Analysis of enzyme kinetics and basic techniques used in molecular Attributes: Writing Intensive Course biology. Prereq: BMCB 751 or permission. Special fee. Writing intensive. Equivalent(s): BCHM 659, BMCB 659 Attributes: Writing Intensive Course Grade Mode: Letter Grade Equivalent(s): BIOT 765 BMCB 750 - Physical Biochemistry Grade Mode: Letter Grade Credits: 3 BMCB 760 - Pharmacology Structure, interactions, and physical-chemical properties of biomolecules. Credits: 4 Thermodynamic, kinetic, and spectroscopic methods for the study Introduction to the basic principles and fundamental concepts of of proteins and nucleic acids. Prereq: CHEM 547 and CHEM 549 and pharmacology, with a focus on molecular mechanisms and pathological CHEM 548 and CHEM 550 or equivalent; MATH 424B or equivalent; or basis of therapeutics
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