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RACKER LECTURES

Year Speaker General talk (Thursday) Technical talk (Friday) 1992 James D. Watson “The RNA Tie Club: Its Search for the “The Human Project” Genetic Code” 1993 Sidney Brenner “The Human Genome” “The Evolution of Genes and ” 1994 Robert Weinberg “Genes and the Molecular Origins of “The Retinoblastoma Protein and Cancer” Control of the Cell Cycle Clock” 1995 Henry Bourne “Stories About Biological Signaling” “How Do Receptors Activate Trimeric G Proteins?” 1996 “Can There Be a Vaccine Against AIDS?” “Cellular Responses to Stress and Change” 1997 Harold Varmus “The Origins of Cancer” “Genes, Mice and Cancer” 1998 Gottfried Schatz “What Cells Tell Us About Life On Earth” “A Novel Mitochondrial Import Pathway for Membrane Proteins” 1999 Joan A. Steitz “Lupus, SNURPS and Molecular “A Tale of Two Spliceosomes” Evolution” 2000 Eric S. Lander “Human and Human Society in “The Human Genome and Beyond” the 21st Century” 2001 Robert J. Lefkowitz “Receptor Regulation and the “Regulation of Heptahelical Receptors: Development of New Cardiovascular Molecular Mechanisms and Drugs” Physiological Implications” 2002 Susan L. Lindquist “From Mad Cows to Psi-Chotic Yeast: “Protein Folding Mechanisms as The Bizarre of ” Capacitors for Evolutionary Change” 2003 “Budding Yeast and the Brain” “Mechanism of Membrane Protein Sorting into Transport Vesicles” 2004 “The Great ideas of Biology” “Cell Cycle Control” 2005 “Enabling a Predictive, Preventive and “: Transforming Biology with Striking and Medicine” Opportunities and Challenges for Society” 2006 Christiane Nusslein- Volhard 2007 Anthony Pawson “Why Matters or “Protein Intersactions in Biological How to get a PhD in Two Weeks” Complexity and Disease” 2008 H. Robert Horvitz “Cell Suicide: Programmed Cell Death “Genetic Control of Programmed Cell in Development and Disease” Death in C. Elegans” RACKER LECTURES

2009 Joseph Schlessinger “Journey of a biophysical chemist in “Cell signaling by receptor tyrosine biomedical research” kinases; from molecules to cancer therapy” 2010 “The Making of a Scientist: An Unlikely “ into the 21st Century: Journey” Mouse Models of Human Disease from Cancer to Neuropsychiatric Disorders” 2011 Aaron Ciechanover “Drug Development in the 21st Century or “The Ubiquitin Proteolytic System: are We Going to Cure all Diseases” From Basic Mechanisms thru Human Diseases and onto Drug Targeting” 2012 Lewis Cantley “The Future of Cancer Prevention and “PI 3-Kinase and Cancer Metabolism” Treatment: moving from Discovery to Implementation” 2013 Ada Yonath “Life Expectancy” “What was first: The genetic code or its products” 2014 Philip A. Sharp “Genes to Biogen, Noncoding to “The Amazing World of Noncoding Alnylam, to Innovation” RNAs”