2004 Albert Lasker Nomination Form
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Unrestricted Immigration and the Foreign Dominance Of
Unrestricted Immigration and the Foreign Dominance of United States Nobel Prize Winners in Science: Irrefutable Data and Exemplary Family Narratives—Backup Data and Information Andrew A. Beveridge, Queens and Graduate Center CUNY and Social Explorer, Inc. Lynn Caporale, Strategic Scientific Advisor and Author The following slides were presented at the recent meeting of the American Association for the Advancement of Science. This project and paper is an outgrowth of that session, and will combine qualitative data on Nobel Prize Winners family histories along with analyses of the pattern of Nobel Winners. The first set of slides show some of the patterns so far found, and will be augmented for the formal paper. The second set of slides shows some examples of the Nobel families. The authors a developing a systematic data base of Nobel Winners (mainly US), their careers and their family histories. This turned out to be much more challenging than expected, since many winners do not emphasize their family origins in their own biographies or autobiographies or other commentary. Dr. Caporale has reached out to some laureates or their families to elicit that information. We plan to systematically compare the laureates to the population in the US at large, including immigrants and non‐immigrants at various periods. Outline of Presentation • A preliminary examination of the 609 Nobel Prize Winners, 291 of whom were at an American Institution when they received the Nobel in physics, chemistry or physiology and medicine • Will look at patterns of -
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Cell Circuitry || Science Teaches English || The Chicken Genome Is Hot || Magnets in Medicine SEPTEMBER 2002 www.hhmi.org/bulletin Leading Doublea Life It’s a stretch, but doctors who work bench to bedside say they wouldn’t do it any other way. FEATURES 14 On Human Terms 24 The Evolutionary War A small—some say too small—group of Efforts to undermine evolution education have physician-scientists believes the best science evolved into a 21st-century marketing cam- requires patient contact. paign that relies on legal acumen, manipulation By Marlene Cimons of scientific literature and grassroots tactics. 20 Engineering the Cell By Trisha Gura Adam Arkin sees the cell as a mechanical system. He hopes to transform molecular 28 Call of the Wild biology into a kind of cellular engineering Could quirky, new animal models help scien- and in the process, learn how to move cells tists learn how to regenerate human limbs or from sickness to health. avert the debilitating effects of a stroke? By M. Mitchell Waldrop By Kathryn Brown 24 In front of a crowd of 1,500, Ohio’s Board of Education heard testimony on whether students should learn about intelligent design in science class. DEPARTMENTS 2 NOTA BENE 33 PERSPECTIVE ulletin Intelligent Design Is a Cop-Out 4 LETTERS September 2002 || Volume 15 Number 3 NEWS AND NOTES HHMI TRUSTEES PRESIDENT’S LETTER 5 JAMES A. BAKER, III, ESQ. 34 Senior Partner, Baker & Botts A Creative Influence In from the Fields ALEXANDER G. BEARN, M.D. Executive Officer, American Philosophical Society 35 Lost on the Tip of the Tongue Adjunct Professor, The Rockefeller University UP FRONT Professor Emeritus of Medicine, Cornell University Medical College 36 Biology by Numbers FRANK WILLIAM GAY 6 Follow the Songbird Former President and Chief Executive Officer, SUMMA Corporation JAMES H. -
NIHAA Summer 1993
The Newsletter of the NIH Alumni Association Summer 1993 Vol. 5, No . 2 date Nobel Laureate Harold Varmus Nominated as 14th NIH Director Ruth Kirschstein Named Acting Director President Clinton on A ug. 3 announced his intention to nominate Dr. Harold Eliot Varmus as the 14th director of th e National Institutes of Health. A Senate confirmation process must precede Yarmus· taking over leadership of the institutes. Winner of the Nobel Prize in 1989 for his work in cancer research. Va1111us. 53. is a professor of microbi ology. biochemistry. and biophysics. and the American Cancer Society pro fessor vfmoh:cu/ur >1iro/O£)' iJI l/Je Uni versity of California, San Francisco. He is a leader in the stu dy of cancer causing genes called "oncogenes," and an intemationall-y fecogni:z.ed authof\t-y Dr. Ruth l. Kirschsteln , acting NIH director on retroviruses. the viruses that cause Dr. Harold E. Varmus , direclor-designale AIDS and many cancers in animnl.. FIC 25 Years Old In '93 Thirty-eight-year NIH veteran Dr. Research Festival '93 Schedule Ruth Kirschstein. director of NIGM S Scholars-in-Residence (See Director p. 6) NIHAA Members Invited Program Celebrates To Alumni Symposium In This Issue Tile fas\ morning ofNCH Rc:-.c;\rch Nursing cell/er /J1·1·111111•s Festival '93-Monday. Sept. 20-has This year. the Fogarty Intern ational 17th i11s1it11tc• 111 NII/ p. ? been designated National lnsritute of Center (FIC) is 25 years old . T he cen Greeri11gs from 1/,11 1w11• NII /AA prl'sidt'lll. Diabetes and Digestive and Kidney Tltolll(IS .I. -
MED C-LIVE Transcript
JUNE 2020 Mario Capecchi, Ph.D. NOT FOR PUBLIC DISTRIBUTION Michael Keel My name is Michael Keel from New Jersey. And it is my honor to introduce Dr. Mario Capecchi. Dr. Capecchi is the Distinguished Professor of Human Genetics at the University of Utah School of Medicine. He is best known for his groundbreaking work in gene targeting, in mass embryo derived stem cells. He was awarded the Nobel Prize in Physiology for Medicine, for his work in finding ways to manipulate the mammalian genome by changing mammals’ genes. His research interests include analysis of neural development in mammals, gene therapy, and production of murine models of human genetic diseases, from cancer to neuropsychiatric disorders. Dr. Capecchi, welcome to the Congress of Future Medical Leaders. Dr. Capecchi Thank you. First of all, welcome to the Medical Leaders’ Congress. It's a pleasure to be here. My name is Mario. I'm going to be talking about gene targeting. Next slide please. My laboratory has developed a technology called gene targeting that allows you to change any gene in any conceivable manner in a living creature, such as a mouse. Next slide. Why do we do gene targeting? Next slide. There are many reasons, but they boil down to two. One is basic research and the other is applied research. In basic research, you investigate the biology of an animal. For example, how do you make a limb or a heart or a brain? Those are basic research questions. The other is applied research. That is we can use gene targeting to generate mice with human diseases. -
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Neuroscience 2013 SEE YOU IN San Diego November 9 – 13, 2013 Join the Society for Neuroscience Are you an SfN member? Join now and save on annual meeting registration. You’ll also enjoy these member-only benefits: • Abstract submission — only SfN members can submit abstracts for the annual meeting • Lower registration rates and more housing choices for the annual meeting • The Journal of Neuroscience — access The Journal online and receive a discounted subscription on the print version • Free essential color charges for The Journal of Neuroscience manuscripts, when first and last authors are members • Free online access to the European Journal of Neuroscience • Premium services on NeuroJobs, SfN’s online career resource • Member newsletters, including Neuroscience Quarterly and Nexus If you are not a member or let your membership lapse, there’s never been a better time to join or renew. Visit www.sfn.org/joinnow and start receiving your member benefits today. www.sfn.org/joinnow membership_full_page_ad.indd 1 1/25/10 2:27:58 PM The #1 Cited Journal in Neuroscience* Read The Journal of Neuroscience every week to keep up on what’s happening in the field. s4HENUMBERONECITEDJOURNAL INNEUROSCIENCE s4HEMOSTNEUROSCIENCEARTICLES PUBLISHEDEACHYEARNEARLY in 2011 s )MPACTFACTOR s 0UBLISHEDTIMESAYEAR ,EARNMOREABOUTMEMBERAND INSTITUTIONALSUBSCRIPTIONSAT *.EUROSCIORGSUBSCRIPTIONS *ISI Journal Citation Reports, 2011 The Journal of Neuroscience 4HE/FlCIAL*OURNALOFTHE3OCIETYFOR.EUROSCIENCE THE HISTORY OF NEUROSCIENCE IN AUTOBIOGRAPHY THE LIVES AND DISCOVERIES OF EMINENT SENIOR NEUROSCIENTISTS CAPTURED IN AUTOBIOGRAPHICAL BOOKS AND VIDEOS The History of Neuroscience in Autobiography Series Edited by Larry R. Squire Outstanding neuroscientists tell the stories of their scientific work in this fascinating series of autobiographical essays. -
書 名 等 発行年 出版社 受賞年 備考 N1 Ueber Das Zustandekommen Der
書 名 等 発行年 出版社 受賞年 備考 Ueber das Zustandekommen der Diphtherie-immunitat und der Tetanus-Immunitat bei thieren / Emil Adolf N1 1890 Georg thieme 1901 von Behring N2 Diphtherie und tetanus immunitaet / Emil Adolf von Behring und Kitasato 19-- [Akitomo Matsuki] 1901 Malarial fever its cause, prevention and treatment containing full details for the use of travellers, University press of N3 1902 1902 sportsmen, soldiers, and residents in malarious places / by Ronald Ross liverpool Ueber die Anwendung von concentrirten chemischen Lichtstrahlen in der Medicin / von Prof. Dr. Niels N4 1899 F.C.W.Vogel 1903 Ryberg Finsen Mit 4 Abbildungen und 2 Tafeln Twenty-five years of objective study of the higher nervous activity (behaviour) of animals / Ivan N5 Petrovitch Pavlov ; translated and edited by W. Horsley Gantt ; with the collaboration of G. Volborth ; and c1928 International Publishing 1904 an introduction by Walter B. Cannon Conditioned reflexes : an investigation of the physiological activity of the cerebral cortex / by Ivan Oxford University N6 1927 1904 Petrovitch Pavlov ; translated and edited by G.V. Anrep Press N7 Die Ätiologie und die Bekämpfung der Tuberkulose / Robert Koch ; eingeleitet von M. Kirchner 1912 J.A.Barth 1905 N8 Neue Darstellung vom histologischen Bau des Centralnervensystems / von Santiago Ramón y Cajal 1893 Veit 1906 Traité des fiévres palustres : avec la description des microbes du paludisme / par Charles Louis Alphonse N9 1884 Octave Doin 1907 Laveran N10 Embryologie des Scorpions / von Ilya Ilyich Mechnikov 1870 Wilhelm Engelmann 1908 Immunität bei Infektionskrankheiten / Ilya Ilyich Mechnikov ; einzig autorisierte übersetzung von Julius N11 1902 Gustav Fischer 1908 Meyer Die experimentelle Chemotherapie der Spirillosen : Syphilis, Rückfallfieber, Hühnerspirillose, Frambösie / N12 1910 J.Springer 1908 von Paul Ehrlich und S. -
Cold Spring Harbor Symposia on Quantitative Biology
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY VOLUME XL COLD SPRING HARBOR SYMPOSIA 0 N Q UA NTITA T1VE BIOLO G Y Founded in 1933 by REGINALD G. HARRIS Director of the Biological Laboratory 1924 to 1936 Volume I (1933).Surface Phenomena Volume II (1934) Aspects of Growth Volume III (1935) Photochemical Reactions Volume IV (1936) Excitation Phenomena Volume V (1937) Internal Secretions Volume VI (1938) Protein Chemistry Volume VII (1939) Biological Oxidations Volume VIII (1940) Permeability and the Nature of Cell Membranes Volume IX (1941) Genes and Chromosomes: Structure and Organization Volume X (1942) The Relation of Hormones to Development Volume XI (1946) Heredity and Variation in Microorganisms Volume XII (1947) Nucleic Acids and Nucleoproteins Volume XIII (1948) Biological Applications of Tracer Elements Volume XIV (1949) Amino Acids and Proteins Volume XV (1950) Origin and Evolution of Man Volume XVI (1951) Genes and Mutations Volume XVII (1952) The Neuron Volume XVIII (1953) Viruses Volume XIX (1954) The Mammalian Fetus: Physiological Aspects of Development Volume XX (1955) Population Genetics: The Nature and Causes of Genetic Variability in Population Volume XXI (1956) Genetic Mechanisms: Structure and Function Volume XXII (1957) Population Studies: Animal Ecology and Demography Volume XXIII (1958) Exchange of Genetic Material: Mechanism and Consequences Volume XXIV (1959) Genetics and Twentieth Century Darwinism Volume XXV (1960) Biological Clocks Volume XXVI (1961) Cellular Regulatory Mechanisms Volume XXVII (1962) Basic -
Biochemistrystanford00kornrich.Pdf
University of California Berkeley Regional Oral History Office University of California The Bancroft Library Berkeley, California Program in the History of the Biosciences and Biotechnology Arthur Kornberg, M.D. BIOCHEMISTRY AT STANFORD, BIOTECHNOLOGY AT DNAX With an Introduction by Joshua Lederberg Interviews Conducted by Sally Smith Hughes, Ph.D. in 1997 Copyright 1998 by The Regents of the University of California Since 1954 the Regional Oral History Office has been interviewing leading participants in or well-placed witnesses to major events in the development of Northern California, the West, and the Nation. Oral history is a method of collecting historical information through tape-recorded interviews between a narrator with firsthand knowledge of historically significant events and a well- informed interviewer, with the goal of preserving substantive additions to the historical record. The tape recording is transcribed, lightly edited for continuity and clarity, and reviewed by the interviewee. The corrected manuscript is indexed, bound with photographs and illustrative materials, and placed in The Bancroft Library at the University of California, Berkeley, and in other research collections for scholarly use. Because it is primary material, oral history is not intended to present the final, verified, or complete narrative of events. It is a spoken account, offered by the interviewee in response to questioning, and as such it is reflective, partisan, deeply involved, and irreplaceable. ************************************ All uses of this manuscript are covered by a legal agreement between The Regents of the University of California and Arthur Kornberg, M.D., dated June 18, 1997. The manuscript is thereby made available for research purposes. All literary rights in the manuscript, including the right to publish, are reserved to The Bancroft Library of the University of California, Berkeley. -
Nobel Laureates Endorse Joe Biden
Nobel Laureates endorse Joe Biden 81 American Nobel Laureates in Physics, Chemistry, and Medicine have signed this letter to express their support for former Vice President Joe Biden in the 2020 election for President of the United States. At no time in our nation’s history has there been a greater need for our leaders to appreciate the value of science in formulating public policy. During his long record of public service, Joe Biden has consistently demonstrated his willingness to listen to experts, his understanding of the value of international collaboration in research, and his respect for the contribution that immigrants make to the intellectual life of our country. As American citizens and as scientists, we wholeheartedly endorse Joe Biden for President. Name Category Prize Year Peter Agre Chemistry 2003 Sidney Altman Chemistry 1989 Frances H. Arnold Chemistry 2018 Paul Berg Chemistry 1980 Thomas R. Cech Chemistry 1989 Martin Chalfie Chemistry 2008 Elias James Corey Chemistry 1990 Joachim Frank Chemistry 2017 Walter Gilbert Chemistry 1980 John B. Goodenough Chemistry 2019 Alan Heeger Chemistry 2000 Dudley R. Herschbach Chemistry 1986 Roald Hoffmann Chemistry 1981 Brian K. Kobilka Chemistry 2012 Roger D. Kornberg Chemistry 2006 Robert J. Lefkowitz Chemistry 2012 Roderick MacKinnon Chemistry 2003 Paul L. Modrich Chemistry 2015 William E. Moerner Chemistry 2014 Mario J. Molina Chemistry 1995 Richard R. Schrock Chemistry 2005 K. Barry Sharpless Chemistry 2001 Sir James Fraser Stoddart Chemistry 2016 M. Stanley Whittingham Chemistry 2019 James P. Allison Medicine 2018 Richard Axel Medicine 2004 David Baltimore Medicine 1975 J. Michael Bishop Medicine 1989 Elizabeth H. Blackburn Medicine 2009 Michael S. -
Moore Noller
2002 Ada Doisy Lectures Ada Doisy Lecturers 2003 in BIOCHEMISTRY Sponsored by the Department of Biochemistry • University of Illinois at Urbana-Champaign Dr. Peter B. 1970-71 Charles Huggins* and Elwood V. Jensen A76 1972-73 Paul Berg* and Walter Gilbert* Moore 1973-74 Saul Roseman and Bruce Ames Department of Molecular carbonyl Biophysics & Biochemistry Phe 1974-75 Arthur Kornberg* and Osamu Hayaishi Yale University C75 1976-77 Luis F. Leloir* New Haven, Connecticutt 1977-78 Albert L. Lehninger and Efraim Racker 2' OH attacking 1978-79 Donald D. Brown and Herbert Boyer amino N3 Tyr 1979-80 Charles Yanofsky A76 4:00 p.m. A2486 1980-81 Leroy E. Hood Thursday, May 1, 2003 (2491) 1983-84 Joseph L. Goldstein* and Michael S. Brown* Medical Sciences Auditorium 1984-85 Joan Steitz and Phillip Sharp* Structure and Function in 1985-86 Stephen J. Benkovic and Jeremy R. Knowles the Large Ribosomal Subunit 1986-87 Tom Maniatis and Mark Ptashne 1988-89 J. Michael Bishop* and Harold E. Varmus* 1989-90 Kurt Wüthrich Dr. Harry F. 1990-91 Edmond H. Fischer* and Edwin G. Krebs* 1993-94 Bert W. O’Malley Noller 1994-95 Earl W. Davie and John W. Suttie Director, Center for Molecular Biology of RNA 1995-96 Richard J. Roberts* University of California, Santa Cruz 1996-97 Ronald M. Evans Santa Cruz, California 1998-99 Elizabeth H. Blackburn 1999-2000 Carl R. Woese and Norman R. Pace 2000-01 Willem P. C. Stemmer and Ronald W. Davis 2001-02 Janos K. Lanyi and Sir John E. Walker* 12:00 noon 2002-03 Peter B. -
Fire Departments of Pathology and Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Room L235, Stanford, CA 94305-5324, USA
GENE SILENCING BY DOUBLE STRANDED RNA Nobel Lecture, December 8, 2006 by Andrew Z. Fire Departments of Pathology and Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Room L235, Stanford, CA 94305-5324, USA. I would like to thank the Nobel Assembly of the Karolinska Institutet for the opportunity to describe some recent work on RNA-triggered gene silencing. First a few disclaimers, however. Telling the full story of gene silencing would be a mammoth enterprise that would take me many years to write and would take you well into the night to read. So we’ll need to abbreviate the story more than a little. Second (and as you will see) we are only in the dawn of our knowledge; so consider the following to be primer... the best we could do as of December 8th, 2006. And third, please understand that the story that I am telling represents the work of several generations of biologists, chemists, and many shades in between. I’m pleased and proud that work from my labo- ratory has contributed to the field, and that this has led to my being chosen as one of the messengers to relay the story in this forum. At the same time, I hope that there will be no confusion of equating our modest contributions with those of the much grander RNAi enterprise. DOUBLE STRANDED RNA AS A BIOLOGICAL ALARM SIGNAL These disclaimers in hand, the story can now start with a biography of the first main character. Double stranded RNA is probably as old (or almost as old) as life on earth. -
Mind Maps in Service of the Mental Brain Activity
PERIODICUM BIOLOGORUM UDC 57:61 VOL. 116, No 2, 213–217, 2014 CODEN PDBIAD ISSN 0031-5362 Forum Mind maps in service of the mental brain activity Summary ŽELJKA JOSIPOVIĆ JELIĆ 1 VIDA DEMARIN 3 Tony Buzan is the creator of the mind maps who based his mnemonic IVANA ŠOLJAN 2 techniques of brain mapping on the terms of awareness and wide brain 1Center for Medical Expertise functionality as well as on the ability of memorizing, reading and creativ- HR-10000 Zagreb, Tvrtkova 5 ity. He conceived the idea that regular practice improves brain functions but Croatia he also introduced radiant thinking and mental literacy. One of the last 2Zagreba~ka banka enormous neuroscience ventures is to clarify the brain complexity and mind HR-10000 Zagreb, Juri{i}eva 22 and to get a complete insight into the mental brain activity. ! e history of Croatia human thought and brain processes dates back in the antiquity and is marked by di" erent ways of looking on the duality of mental and physical 3Medical Director, Medical Centre Aviva HR-10000, Zagreb, Nemetova 2 processes. ! e interaction of mental and physical processes and functioning Croatia of individual results in behavior of the body being carved in the state of mind, and vice versa. Both stable mind - body relation and integrated func- tions of behavior and thinking are necessary for a healthy physiological func- Correspondence: tioning of a human being. @eljka Josipovi} Jeli} Specialist neuropsychiatrist ! e meaning and nature of concience and mind preoccupies as all. In Center for Medical Expertise the decade of brain (1990-2000) and the century of brain (2000-1000) HR-10000 Zagreb, Tvrtkova 5, Croatia numerous discussions were lead and new scienti# c directions formed (cogni- E-mail: zeljka.josipovic-jelic @si.t-com.hr tive science, chemistry of feelings, evolutionary psychology, neurobiology, neurology of consciousness, neurophysiology of memory, philosophy of science and mind etc.) in order to understand and scientifcally clarify the mysteries of mind.