Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_001426435Cyc: Angustibacter sp. Root456 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari

RS08735 RS09430 RS05380 RS06195 RS02770 SecG SecA FliO RS04605 RS01770 CrcB RS16510 RS08515 RS08840 RS07870 RS01490 RS14545 RS13000 RS09630 RS03855 RS09575 RS10695 RS07780 RS07930 RS01655 YajC RS08720 RS05150 FliG RS12940 RS07875 RS00615 RS07370 MreD RS15470 RS15795

Amino Acid Degradation Amine and Metabolic Regulator Aromatic Compound Degradation/ Polyprenyl Biosynthesis + + gln Macromolecule Modification H RS12100 H RS04220 glutaminyl-tRNA Aminoacyl-tRNA Charging Polyamine Biosynthesis Biosynthesis tRNA processing Utilization/ α di-trans,octa-cis UDP-N-acetyl- di-trans,octa-cis UDP-N-acetyl- 4-amino-4- -D-Kdo-(2->4) a [protein]- a DNA methyl UDP-N-acetyl- (S)-1-pyrroline- biosynthesis via transamidation L-threonine + a ribonucleoside an L-asparaginyl- an L-cysteinyl- Biosynthesis L-glutamate Assimilation - Other -undecaprenyl α -undecaprenyl α α -α-D-Kdo-(2->6) menadione NADH H α di-trans,poly-cis L-arginine degradation V -D-muramoyl- -D-muramoyl- deoxy- -L- L-cysteine phosphotriester -D-muramoyl- Asn Cys 5-carboxylate ppGpp metabolism chorismate biosynthesis I a polycistronic degradation I L-arginine degradation L-tryptophan degradation to diphosphate [tRNA ] [tRNA ] dGDP putrescine -undecaprenyl (arginine deiminase pathway) XIII (reductive 2-amino-3-carboxymuconate degradation VI acrylonitrile phosphate L-alanyl-γ-D- phosphate L-alanyl-γ-D- arabinopyranosyl -lipid A (E. coli) L-alanyl-γ-D- vitamin B12- L-glutamate glu biosynthesis I tRNA precursor (to pyruvate) degradation I gamma- vitamin B12- F0F1 ATP phosphate biosynthesis D-erythrose Stickland reaction) semialdehyde glutamyl-L-lysyl- glutamyl-L- ditrans,octacis glutamyl-meso-2,6- dependent H + H + pppGpp thr methylated-DNA-- NADH-quinone semialdehyde dependent synthase FliD (2E,6E)-farnesyl 4-phosphate arg D-alanyl-D-alanine lysyl-D-alanine -undecaprenyl diaminopimeloyl- ribonucleotide aminoacyl-tRNA aminoacyl-tRNA IPP 3-deoxy-7- threonine/serine arg trp glu acrylonitrile [protein]-cysteine S- oxidoreductase: dehydrogenase: ribonucleotide gln arg diphosphate phospho-N- phospho-N- phosphate D-alanyl-D-alanine reductase: hydrolase: hydrolase: dehydratase: methyltransferase: nuoK nuoH pruA reductase: phosphoheptulonate arginine deiminase: tryptophan 2,3- ASD06_RS11270 ASD06_RS14675 ASD06_RS14675 bifunctional (p)ppGpp ASD06_RS15800 arginine deiminase: acetylmuramoyl- acetylmuramoyl- ASD06_RS17200 ASD06_RS11270 synthase class II: a tRNA precursor a tRNA precursor with ASD06_RS16330 dioxygenase: glutamate mutase: NADH-quinone imidazole an L-glutamyl- isoprenyl synthetase/guanosine- ASD06_RS16330 pentapeptide- pentapeptide- 4-amino-4-deoxy- D-alanyl-D-alanine ribonucleotide- aminoacyl- aminoacyl- L-glutamate RS04185 3-deoxy- ASD06_RS11390 with a 5' extension a 5' extension and threonine kynA ASD06_RS03460 acrylamide methylated-DNA-- oxidoreductase: ribonucleotide- RS00140 glycerol [tRNA Gln ] agmatine transferase: 3',5'-bis(diphosphate) 3'- L-citrulline N-Formyl-L- transferase: transferase: L-arabinose carboxypeptidase/ diphosphate tRNA tRNA gamma- D-arabino- and a long 3' trailer a short 3' extension ammonia-lyase: [protein]-cysteine S- nuoN diphosphate phosphate ASD06_RS13400 pyrophosphohydrolase: L-citrulline kynurenine (2S, 3S)-3- ASD06_RS18265 ASD06_RS18265 transferase: D-alanyl-D-alanine- reductase: hydrolase: hydrolase: semialdehyde Asp-tRNA(Asn) heptulosonate ribonuclease D: ribonuclease ASD06_RS03480 amidase: methyltransferase: ASD06_RS08915 reductase: synthase agmatinase: (2Z)-2-aminobut- ornithine methylaspartate ASD06_RS06535 endopeptidase: dacB ASD06_RS02745 arfB arfB dehydrogenase: /Glu-tRNA(Gln) isoprenyl ASD06_RS06980 ASD06_RS07290 ribonuclease P protein ASD06_RS15305 phospho-N- phospho-N- ASD06_RS17230 subunit speB 7-phosphate 2-enoate carbamoyltransferase: nuoK ASD06_RS02750 pruA ASD06_RS02745 amidotransferase: transferase: ribonuclease D: PH: rph component: amidase: acetylmuramoyl- acetylmuramoyl- [+ 2 isozymes] a 2'- HisF: hisF agmatinase: 3-dehydroquinate argF α α ASD06_RS08930 ASD06_RS02750 FlgK ASD06_RS03670 ASD06_RS07290 rnpA ornithine ASD06_RS00630 pentapeptide- pentapeptide- di-trans,octa-cis 4'- -L-Ara4N- - deoxyribonucleoside glu gatB gatA gatC speB synthase: nuoI nuoH GDP RS12810 [+ 8 isozymes] GTP ppGpp carbamoyltransferase: transferase: transferase: -undecaprenyl Kdo-(2->4)-α- a [protein]-S- asn tRNA Asn cys a tRNA Cys a 5-phosphooxy- ASD06_RS06810 a tRNA precursor with L-ornithine L-kynurenine [DNA] ASD06_RS08945 UDP-N- 5'-diphosphate di-trans,octa-cis argF acrylate ASD06_RS12505 ASD06_RS12505 phosphate Kdo-(2->6)-[P4'- methyl-L-cysteine ammonium L-glutamyl- putrescine a short 3' extension mesaconate nuoF nuoE D-ala acetylmuramoyl- Gln -undecaprenyl 2-iminobutanoate α-L-ara4N]-lipid A [tRNA ] 3-dehydroquinate a tRNA precursor ornithine- undecaprenyl- UMP undecaprenyl- UMP ASD06_RS08960 L-alanyl-γ-D- diphosphate nucleoside- bifunctional (p)ppGpp with a 5' extension carbamoyl glutamyl-meso-2,6- RS09190 L-ornithine -oxo-acid diphospho-N- diphospho-N- ASD06_RS08965 Asp-tRNA(Asn) undecaprenyl- diphosphate synthetase/guanosine- type II 3- phosphate ribonuclease ribonuclease D: transaminase: acetylmuramoyl- acetylmuramoyl- ASD06_RS08975 diaminopimeloyl- /Glu-tRNA(Gln) diphosphate kinase: ndk 3',5'-bis(diphosphate) 3'- dehydroquinate 3-hydroxy- γ γ RS03590 ribonuclease PH: rph ASD06_RS07290 carbamate kinase: rocD L-alanyl- -D- L-alanyl- -D- D-alanine amidotransferase: phosphatase: pyrophosphohydrolase: dehydratase: aroQ L-kynurenine P protein 2-oxobutanoate ASD06_RS06520 (S)-citramalate glutamyl-L-lysyl- glutamyl-L- gatB gatA gatC ASD06_RS05840 ASD06_RS06980 L-glutamate-5- D-alanyl-D-alanine lysyl- D-alanine + di-trans,octa-cis 3-dehydroshikimate component: glutamine- semialdehyde kynureninase: NAD menadiol RS05420 -undecaprenyl rnpA hydrolyzing kynU citramalate an L-glutaminyl- shikimate tRNA charging phosphate GDP carbamoyl- synthase: Gln dehydrogenase: [tRNA ] 6 RS01095 phosphate 3-hydroxyanthranilate ASD06_RS00640 N -(3-methylbut- a DNA containing sn-glycero-3- a mature (4R)-4-hydroxy- D-sedoheptulose ASD06_RS06890 Glycolysis propanoyl-CoA a sulfurated hydrogen selenide a [glutamine- a holo [D-alanyl synthase: (S)-1-pyrroline- 2-en-1-yl)- O-acetyl-L-serine an apurinic/ phospho-N- peptidoglycan 2-oxoglutarate D-ala 1,7-bisphosphate met Trp Pro (n) ATP dADP trp a tRNA pro a tRNA [sulfur carrier] 37 synthetase]- carrier protein] shikimate carB carA 5-carboxylate adenosine apyrimidinic site (arachidonoyl) (meso-DAP an uncharged tRNA acetate pyruvate L-tyrosine bifunctional vitamin B12- glycolysis III (from glucose) pyrroline-5- in tRNA ethanolamine containing) glutamate N- a tRNA Ala ala tRNA asp asp ser a tRNA ser phe a tRNA Phe carbamate 2-amino-3- bifunctional fructose- dependent elongator shikimate kinase: carboxylate bifunctional o- endonuclease cysteine--1-D-myo- acetyltransferase/ glu glu arg Arg val Val ile Ile leu Leu his His thr Thr lys Lys tryptophan- tyr Tyr proline-- gly Gly met Met met cys Cys carboxymuconate- 4-hydroxy-2- bisphosphate ribonucleotide a tRNA a tRNA a tRNA a tRNA a tRNA a tRNA a tRNA a tRNA a tRNA a tRNA Met initiator tRNA a tRNA ASD06_RS06815 propanoyl succinate acetylhomoserine/ -tRNA tRNA ligase: tRNA D-glucopyranose reductase: III: nth glycerophosphodiester lytic bifunctional [glutamine inosityl 2-amino- amino-acid RS09425 phosphate 6-semialdehyde dehydrogenase o-acetylserine oxoglutarate aldolase: reductase: Asn Gln proC synthetase] alanine- aspartate- ligase: trpS ASD06_RS12380 serine- phenylalanine- asn tRNA gln a tRNA shikimate 3- L-proline bifunctional DNA- phosphodiesterase: transglycosylase aldolase/2- 2-deoxy-alpha-D- ASD06_RS17155 acetyltransferase ASD06_RS11270 lipoprotein posttranslational modification ROK family hydrophobic sulfhydrylase: adenylyltransferase/ glutamate-- arginine-- valine- isoleucine-- leucine-- -tRNA -tRNA histidine-- threonine-- lysine- tryptophan- tyrosine-- proline-- glycine-- methionine-- methionine-- cysteine-- -tRNA -tRNA ligase: phosphate acetate/propionate degradation I L-histidine degradation I formamidopyrimidine ASD06_RS05545 domain-containing dehydro-3-deoxy- glucopyranoside ArgJ: argJ glucokinase: pro membrane ASD06_RS05220 [glutamine synthetase]- class II fructose- ribonucleotide- tRNA ligase: tRNA ligase: -tRNA tRNA ligase: tRNA ligase: ligase: ligase: tRNA ligase: tRNA ligase: -tRNA -tRNA tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: ligase: ASD06_RS12325 3-phosphoshikimate 1- family kinase: CO glycosylase/ glycerophosphodiester protein: phosphogluconate ligase: amino-acid N- a [prolipoprotein]- ASD06_RS11440 2 anchor subunit: cysteine adenylyl-L-tyrosine bisphosphate diphosphate ASD06_RS00545 ASD06_RS01265 ligase: valS ASD06_RS03960 ASD06_RS04165 alaS aspS ASD06_RS06955 ASD06_RS07095 ligase: lysS ligase: trpS ASD06_RS12270 ASD06_RS13070 ASD06_RS13365 ASD06_RS14515 ASD06_RS14515 ASD06_RS14950 serS pheS carboxyvinyltransferase: ASD06_RS13840 pro DNA-(apurinic phosphodiesterase: ASD06_RS18375 aldolase: eda ASD06_RS05815 acetyltransferase: L-cysteine ROK family his ASD06_RS03140 synthase A: cysK phosphorylase: aldolase: fbaA reductase: aroA propanoate proline or apyrimidinic ASD06_RS16355 [+ 2 isozymes] ASD06_RS09385 RS08180 prolipoprotein glucokinase: histidine tRNA (N6-isopentenyl ASD06_RS12120 N-acetyl-L- ASD06_RS02745 an L-methionyl- 5-enolpyruvoyl- dehydrogenase: site) lyase: mutM a D-alanyl- an L-glutamyl- an L-arginyl- an L-valyl- an L-isoleucyl- an L-leucyl- an L-alanyl- an L-aspartyl- an L-histidyl- an L-threonyl- an L-lysyl- an L-tryptophanyl- an L-tyrosyl- an L-prolyl- Gly an L-methionyl- an L-cysteinyl- an L-seryl- an L-phenylalanyl- an L-asparaginyl- an L-glutaminyl- ammonia- ASD06_RS02750 a glycyl-[tRNA ] [elongator shikimate 3- diacylglyceryl ASD06_RS11445 adenosine(37)-C2)- D-erythrose methionine [tRNA Glu ] [tRNA Arg ] [tRNA Val ] [tRNA Ile ] [tRNA Leu ] [tRNA Ala ] [tRNA asp ] [tRNA His ] [tRNA Thr ] [tRNA Lys ] [tRNA Trp ] [tRNA Tyr ] [tRNA Pro ] [initiator tRNA Met ] [tRNA Cys ] [tRNA ser ] [tRNA Phe ] [tRNA Asn ] [tRNA Gln ] ASD06_RS09300 acetate a mature GlcNAc-1,6- glyoxylate pyruvate [D-alanyl DHAP Met (S)-1-pyrroline- lyase: hutH methylthiotransferase L-selenocysteine sn-glycerol 4-phosphate ADP tRNA ] phosphate transferase: D-glucopyranose anandamide peptidoglycan anhMurNAc- a [glutamine carrier protein] 5-carboxylate urocanate MiaB: miaB a 3'-terminal a 5'-phospho- 3-phosphate (n) chorismate ASD06_RS06440 6-phosphate (meso-DAP L-Ala-γ-D-Glu- synthetase]-O a [prolipoprotein]- unsaturated sugar [DNA] 4 -(5'-adenylyl) synthase: glucose-6- L-tryptophan urocanate 6 containing) DAP-D-Ala S-1,2-diacyl-sn- N -(3-methylbut- RS03100 aroC phosphate degradation I hydratase: 5'-deoxyadenosine an unsulfurated -L-tyrosine glyceryl-L-cysteine 2-en-1-yl)-2- met isomerase: (via anthranilate) ASD06_RS17615 [sulfur carrier] chorismate L-glutamate-5- (methylsulfanyl) ASD06_RS06220 semialdehyde 4-imidazolone- adenosine 37 signal trp 5-propanoate in tRNA peptidase F6P tryptophan 2,3- L-glutamate glycine cleavage UMP biosynthesis III Nucleoside and Nucleotide Biosynthesis II: lspA imidazolonepropionase: superpathway of guanosine superpathway of inosine-5'-phosphate biosynthesis I pyrimidine deoxyribonucleotides de novo biosynthesis I xanthine and adenine and adenosine salvage III CMP dioxygenase: gamma- a [glycine-cleavage FtsE ASD06_RS17635 4 Secondary Metabolite Biosynthesis xanthosine salvage phosphorylation kynA semialdehyde 6 a ring-opened 7- an O - a [glutamine nucleotides de novo biosynthesis I adenosine nucleotides an (S-diacyl-sn- N-Formyl-L- complex H protein] N quinoxaline-2- a [protein]- O-succinyl-L- a [protein]- D-sedoheptulose UDP UDP CTP a lipoprotein dehydrogenase: glycine methylguanine aryl-carrier protein methylthymine a [protein]-L-lysine synthetase]-O a RNA-DNA hybrid 3-sulfino-L-alanine gln hydrogencarbonate de novo biosynthesis I AIR CMP glyceryl)-L-cysteinyl- kynurenine -[(R)-lipoyl]-L-lysine N-formimino- carboxyl adenylate L-cysteine L-glutamine 1-phosphate IMP signal peptide β cleavage in DNA homoserine 4 vitamin B12- streptorubin B biosynthesis 5-(carboxyamino)imidazole ribonucleotide- adenine [apolipoprotein] -D-fructose 1,6- pruA L-glutamate in DNA -(5'-adenylyl) methylerythritol phosphate pathway I IMP xanthosine (d)CMP glycine system bifunctional dependent ribonucleotide synthase: diphosphate reductase: purine-nucleoside bisphosphate L-glutamate -L-tyrosine IMP asp CDP purine-nucleoside kinase: cmk apolipoprotein N- cleavage protein transglutaminase bifunctional fructose- metallophosphatase/ ribonucleotide glutamine- ASD06_RS02790 ASD06_RS02745 phosphorylase: CDP gamma- formamidopyrimidine- acyl carrier protein: methylated-DNA-- O-succinylhomoserine SufS family acetyl-CoA D-glyceraldehyde acyltransferase: lnt system domain-containing RNase H/acid bisphosphate reductase: RS02960 pyruvate IMP ASD06_RS02750 phosphorylase: fructose- GcvH: gcvH [protein]-cysteine S- 5'-nucleotidase: hydrolyzing N5-CAIR superpathway of pyrimidine deoxyribonucleoside salvage ribonucleotide- ASD06_RS02970 semialdehyde protein DNA glycosylase: ASD06_RS17170 sulfhydrylase: bifunctional [glutamine ASD06_RS11270 cysteine 3-phosphate dehydrogenase: ASD06_RS02970 nucleoside- an N-acyl-(S-diacyl- L-kynurenine methyltransferase: protein: phosphatase: aldolase: ASD06_RS10615 ketoacyl-ACP carbamoyl- vitamin B12-dependent diphosphate reductase: adenosine a peptide bisphosphate dehydrogenase: GcvH: gcvH [+ 4 isozymes] ASD06_RS08675 acyl carrier protein: ASD06_RS04770 synthetase] desulfurase: guaB adenylosuccinate xanthine diphosphate sn-glyceryl)-L- ASD06_RS17010 ASD06_RS04780 ASD06_RS17155 ribonucleotide- phosphate 5-(carboxyamino)imidazole ribonucleotide reductase: ASD06_RS02745 aldolase: pruA a [glycine-cleavage glu ASD06_RS17200 bifunctional sufS synthase III: 1-deoxy-D- synthase: 2'-deoxycytidine kinase: ndk cysteinyl-[lipoprotein] [+ 5 isozymes]a [glycine-cleavage bifunctional DNA- ASD06_RS04850 cystathionine adenylyltransferase/ synthase: ribonucleotide mutase: purE ASD06_RS17155 kynureninase: 6 transglutaminase ribonuclease HII: class II fructose- metallophosphatase/ diphosphate ASD06_RS04845 ASD06_RS11270 ASD06_RS02750 adenosine deaminase: 6 complex H protein] N - methylated-DNA-- gamma-synthase: [glutamine synthetase]- xylulose-5- XMP ASD06_RS17980 complex H protein] N formamidopyrimidine domain-containing ASD06_RS00275 bisphosphate reductase: carB carA dUDP ASD06_RS08565 CTP class II fructose- kynU glu aminomethyldihydrolipoyl- [protein]-cysteine S- adenylyl-L-tyrosine 5'-nucleotidase: phosphate nucleoside vitamin B12-dependent -dihydrolipoyl-L-lysine glycosylase/ a quinoxaline-2- ASD06_RS03455 aldolase: fbaA ASD06_RS02745 CAIR L-lysine methyltransferase: protein: ASD06_RS15155 sulfite RS05930 an acetoacetyl-[acp] synthase: dxs deaminase: nucleoside- ribonucleotide reductase: adenosine deaminase: bisphosphate DNA-(apurinic carboxyl-[aryl- phosphorylase: ala glutamine- adenylo-succinate anthranilate AMP ASD06_RS17230 ASD06_RS12550 inosine ASD06_RS02750 carbamoyl ASD06_RS15720 dCMP diphosphate kinase: ndk ASD06_RS11270 ASD06_RS03070 5-oxo-L-proline metabolism aldolase: fbaA or apyrimidinic carrier protein] ASD06_RS12120 a nucleoside 5'- asp hydrolyzing GMP phosphoribosylaminoimidazolesuccinocarboxamide XMP L-serine degradation DNA dUDP 3-oxoacyl- phosphate site) lyase: mutM succinate monophosphate D-erythrose 1-deoxy-D-xylulose synthase: guaA adenylosuccinate synthase: ASD06_RS18000 cytidine (d)CMP dUTP dCDP L-homocysteine a protein with an DHAP [acyl-carrier- 5-phosphate deaminase: inosine a [protein] with a [protein] with a [protein]-S- a [glutamine- triose-phosphate L-arginine glycine a thymine in DNA N 6 -(γ-glutamyl)- protein] lyase: purB kinase: cmk dUTP diphosphatase: dut nucleoside- an N-terminal an N-terminal methyl-L-cysteine 1-deoxy-D-xylulose- aspartate SAICAR ASD06_RS03090 isomerase: L-asparagine degradation cleavage ser a [DNA]- 2,6-diamino-4- L-lysine crosslink synthetase]- reductase: GMP nucleotide diphosphate kinase: ndk purine-nucleoside L-glutamine L-glutamate a 5'-phospho- ADP RS05895 5-phosphate carbamoyltransferase dCDP ASD06_RS06255 L-glutamine degradation I system threonine/serine nucleotide- hydroxy-5-(N-methyl) 4-oxo-2-pentenal L-tyrosine fabG D-glyceraldehyde III (arginine [DNA] reductoisomerase: catalytic subunit: AMP adenylosuccinate 2'-deoxyuridine pyrophosphohydrolase: dCTP phosphorylase: Tetrapyrrole Biosynthesis DHAP degradation I protein 3'-phosphate formamidopyrimidine a (3R)-3- nucleoside- 3-phosphate decarboxylase/ dehydratase: ASD06_RS13105 ASD06_RS06785 guanylate lyase: purB ASD06_RS11120 ASD06_RS02970 GcvH: gcvH hydroxybutanoyl- diphosphate asn agmatinase pathway) 2-aminoprop-ASD06_RS15800 kinase: gmk thymidine kinase: type I arg kinase: ndk dUMP tetrapyrrole biosynthesis gln asparaginase: [+ 4 isozymes] 6 [acp] adenylate kinase: AICAR hypoxanthine heme a biosynthesis a [protein] with glyceraldehyde- 2-enoate a 7,8-dihydro- a peptidoglycan dimer (meso a [protein]- an O - a peptidoglycan a [bis(guanylyl a [protein]- an N-terminal- a [DNA]-3'- a 5'-phospho- an N-terminal- dCDP MEP ASD06_RS07450 I (from glutamate) γ-L-glutamyl imidazole glycerol ASD06_RS08790 serotonin N-carbamoyl- ASD06_RS08325 dCTP thymidylate synthase: an N-terminal 5- 3-phosphate 8-oxoguanine -diaminopimelate containing) L-cysteine methylguanine dimer (E. faeciums) molybdopterin) cys L-glutamine L-methionyl-L- hydroxyl [DNA] L-methionyl-L- L-selenocysteine thymidine 5-phosphate glutathione phosphate synthase vitamin B12- RS10095 L-aspartate GDP bifunctional ASD06_RS12895 5-aminoimidazole ribonucleotide biosynthesis I oxo-L-proline dehydrogenase: asparaginase: in DNA in DNA cofactor threonyl-[protein] seryl-[protein] 2-C-methyl-D- dUMP protoheme subunit HisF: hisF agmatine dependent phosphoribosylaminoimidazolecarboxamide hypoxanthine glu gap ASD06_RS15060 chaperone]- erythritol 4-phosphate dihydroorotase: ADP dTMP phosphoribosyltransferase: hpt protoheme IX [+ 8 isozymes] asp L-glutamine D-alanyl-D-alanine D-alanyl-D-alanine transglutaminase ATP-dependent ribonucleotide a (2E)-but- formyltransferase/IMP cyclohydrolase: purH thymidine kinase: glutamate-- 2-iminopropanoate formamidopyrimidine- methylated-DNA-- L-cysteine type I methionyl type I methionyl SufS family cytidylyltransferase: ASD06_RS06780 thymidylate PRPP farnesyltransferase: glu agmatinase: degradation II carboxypeptidase/ carboxypeptidase/ domain-containing DNA ligase: reductase: 2-enoyl-[acp] ASD06_RS07450 dTMP kinase: tmk tRNA ligase: 13-DPG DNA glycosylase: [protein]-cysteine S- aminopeptidase: aminopeptidase: cysteine ASD06_RS14970 nucleoside- ribonucleotide- ribonucleotide- FAICAR synthase: ASD06_RS06205 speB D-alanyl-D-alanine- D-alanyl-D-alanine- protein: ASD06_RS05200 ASD06_RS11270 an L-glutamyl-ASD06_RS00545 ASD06_RS08675 methyltransferase: map map desulfurase: enoyl-ACP 4-(cytidine 5'- (S)-dihydroorotate diphosphate diphosphate diphosphate ASD06_RS12895 amidophosphoribosyltransferase: IMP ferroheme o 5-oxo-L-proline agmatinase: endopeptidase: dacB endopeptidase: dacB cysteine ASD06_RS17010 dTDP Glu phosphoglycerate gln ASD06_RS17200 ATP-dependent ribonucleotide- reductase diphospho)-2-C- kinase: ndk reductase: bifunctional ASD06_RS18080 [tRNA ] [+ 2 isozymes] [+ 2 isozymes] desulfurase: [+ 2 isozymes] [+ 2 isozymes] sufS RarD reductase: superpathway of pyrimidine kinase: speB glutamate bifunctional DNA- transglutaminase DNA ligase: diphosphate FabI: fabI methyl-D-erythritol dihydroorotate ASD06_RS02745 phosphoribosylaminoimidazolecarboxamide nucleoside- β heme A synthase: 5-oxoprolinase methylated-DNA-- ASD06_RS00795 ASD06_RS02745 5-phospho- - gly nucleobases salvage glutamyl-tRNA ASD06_RS06260 L-glutamate synthase large pyruvate formamidopyrimidine domain-containing ASD06_RS07215 reductase: 4-(cytidine 5'- dehydrogenase ASD06_RS02750 formyltransferase/IMP cyclohydrolase: purH diphosphate kinase: ndk ASD06_RS06200 subunit putrescine [protein]-cysteine S- enoyl-ACP ASD06_RS02750 D-ribosylamine reductase: degradation I subunit: gltB glycosylase/ a peptidoglycan with a peptidoglycan protein: an N-terminal L- an N-terminal ASD06_RS02745 diphospho)- dTMP uracil PxpA: pxpA 3-phospho- methyltransferase: selenide reductase: electron GTP vitamin B12- dTTP ASD06_RS09145 DNA-(apurinic D,D cross-links (meso- D-ala tetramer with a D-ala a [bis(guanylyl met threonyl-[protein] met L-seryl-[protein] ASD06_RS02750 ala 2-C-methyl-D- vitamin B12- uracil ferroheme i D-glycerate glu ASD06_RS17230 ASD06_RS12550 ASD06_RS08065 transfer subunit: dependent IMP phosphoribosylamine- or apyrimidinic diaminopimelate containing) D,D cross-link ala molybdopterin) [DNA] dependent dTMP kinase: tmk phosphoribosyltransferase: upp (S)-4-amino-5- glu CDP erythritol kinase: ASD06_RS06760 ribonucleotide glu phosphoglyceromutase: site) lyase: mutM cofactor RS08820 ribonucleotide -glycine ligase: purD oxopentanoate NAD-glutamate (Enterococcus 6 a butanoyl-[acp] ASD06_RS14595 adenine and bifunctional pyr operon heme A synthase: Secondary Metabolite Degradation a [protein]-S- chaperone]-S- a [protein] N - dihydroorotate reductase: reductase: dTDP ASD06_RS15015 a guanine in DNA faecium) 2-phospho-4-(cytidine adenosine salvage I transcriptional regulator/uracil glutamate-1- ASD06_RS06200 dehydrogenase: methyl-L-cysteine sulfanyl-L-cysteine [(5-hydroxy-1H- dehydrogenase: ASD06_RS11270 ASD06_RS11270 guanine and guanosine salvage guanine and guanosine salvage II 2-phospho- ASD06_RS10185 a [DNA]- beta- 5'-diphospho)-2-C- nucleoside- GAR phosphoribosyltransferase semialdehyde myo-inositol degradation I a 5'-phospho- 7,8-dihydro- indol-3-yl)ethyl]- ASD06_RS06755 hydroxyferroheme i periplasmic disulfide bond formation D-glycerate 2-oxoglutarate nucleotide- 4-oxo-2-pentenal ketoacyl- methyl-D-erythritol diphosphate PyrR: pyrR 2,1- D-galactonate degradation [DNA] 8-oxoguanine L-glutamine PRPP phosphoribosylglycinamide 3'-phosphate ACP 2-C-methyl-D- orotate dADP adenosine kinase: ndk UMP aminomutase: phosphopyruvate a [DsbB protein] a [DsbA protein] two reduced myo-inositol erythritol 2,4- dGDP purine-nucleoside guanosine guanosine formyltransferase: hemL an electron- RS12600 synthase UMP kinase: with reduced L- carrying a cysteine residues hydratase: eno D-galactonate cyclodiphosphate phosphorylase: dTTP purine-nucleoside ASD06_RS07655 L-alanyl-γ-D- a [protein]-L- an N-terminal- II: fabF orotate nucleoside- transfer quinone inositol 2- a purine base UDP-N-acetylmuramoyl- ASD06_RS02970 ASD06_RS13290 5-aminolevulinate cysteine residues disulfide bond in a protein phosphoenol galactonate 2-methylbutanoate H O an N-modified 5 15-cis-phytoene synthase: phosphoribosyltransferase: nucleoside- diphosphate phosphorylase: DL-allothreonine L-alanyl-γ-D- 2 glutamyl-meso-2,6- glutamate-O L-methionyl-L- FGAR ferroheme a pyruvate Carboxylate Degradation dehydrogenase: lesion in DNA GTP aminoacyl-[tRNA] ATP roseoflavin a 3-oxohexanoyl- ASD06_RS14965 diphosphate adenine ASD06_RS02970 UDP dehydratase: diaminopimeloyl- -methyl-ester valyl-[protein] phytoene ASD06_RS17860 kinase: ndk iolG glutamyl-meso-2,6- 5'-phosphate [acp] porphobilinogen pyruvate dgoD desaturase: 2-C-methyl-D-erythritol- kinase: ndk guanine guanine phosphoribosylformylglycinamidine nucleoside- diaminopimeloyl- D-alanine adenine synthase: hemB kinase: pyk propanoyl CoA formamidopyrimidine- acetate--CoA 3-oxoacyl- orotidine 5'- dATP synthase: purS purQ purL pyruvate decarboxylation to acetyl CoA I acetate scyllo-inosose 2-dehydro-3-deoxy- serine D-alanine aminoacyl-tRNA chemotaxis type I methionyl crtI 2,4-cyclodiphosphate phosphoribosyltransferase: diphosphate kinase: ndk degradation I DNA glycosylase: ligase: acs ribosome RS00085 [acyl-carrier- phosphate dGTP conversion D-galactonate hydroxymethyltransferase: hydrolase: LD- response regulator aminopeptidase: bifunctional phytoene flavodoxin- ASD06_RS06985 hypoxanthine hypoxanthine UTP porphobilinogen pyruvate ASD06_RS08675 acetate--CoA biogenesis protein] FGAM a [pyruvate dehydrogenase to acetyl-CoA ASD06_RS16480 LD- ASD06_RS14675 carboxypeptidase: protein-glutamate map riboflavin kinase/ desaturase: dependent phosphoribosyltransferase: hpt phosphoribosyltransferase: hpt propanoyl-CoA GTPase Der: reductase: orotidine-5'- CTP synthase: E2 protein] N 6 -lipoyl-L-lysine bifunctional DNA- ligase: acsA FAD synthetase: crtI hydroxymethylbilane propionyl-CoA pyruvate acetate serine carboxypeptidase: ASD06_RS05355 aminoacyl- ASD06_RS14320 methylesterase: [+ 2 isozymes] (E)-4-hydroxy- phosphate AMP phosphoribosylformylglycinamidine ASD06_RS07505 3D-(3,5/4)- formamidopyrimidine ASD06_RS12980 9,15,9'-tri-cis fabG synthase: hemC carboxylase pyruvate acetate--CoA 2-dehydro-3-deoxy- hydroxymethyltransferase: ASD06_RS14320 ASD06_RS12255 a (3R)-3- 3-methylbut- decarboxylase: GMP GMP cyclo-ligase: ASD06_RS18085 pyruvate trihydroxycyclohexane- glycosylase/ [+ 6 isozymes] tRNA -ζ-carotene CTP subunit beta: dehydrogenase ligase: acs D-galactonate (2S)-2- ASD06_RS01195 L-alanyl-γ-D- hydroxyhexanoyl- 2-enyl- pyrF dehydrogenase: 1,2-dione DNA-(apurinic diphosphate hydrolase: an N-terminal FliQ preuroporphyrinogen NADH repair (eukaryotes) ASD06_RS04860 (acetyl- 6-phosphate methylbutanoyl-CoA AMP UDP-N-acetyl-α-D- D-ala glutamyl-meso- roseoflavin diphosphate AIR ASD06_RS10575 acetate--CoA + arfB a [protein]-α- met [acp] transferring), 3D-(3,5/4)- or apyrimidinic phosphate H MeOH L-valyl-[protein] adenine synthase: ispG UMP [+ 2 isozymes] ligase: acsA D-ala muramoyl-L-alanyl- GDP diaminopimelate bifunctional DsbA family (S)-methylmalonyl- dihydrolipoyl homodimeric trihydroxycyclohexane- site) lyase: mutM L-glutamate dinucleotide (E)-4-hydroxy-3- acetyl-CoA acetaldehyde γ-D-glutamyl-meso- uroporphyrinogen-III oxidoreductase: NADH CoA dehydrogenase: type: aceE 1,2-dione acylhydrolase gly methylbut-2-en- 2,6-diaminopimelate an N-modified an uncharged C-methyltransferase/ ASD06_RS14050 methylmalonyl- lpdA (decyclizing): iolD a [DNA]- 1-yl diphosphate a [DsbB protein] a [DsbA protein] [+ 3 isozymes] D-glyceraldehyde a 5'-phospho- a modified amino acid tRNA a (2E)-hex- uroporphyrinogen- an electron- an intra- CoA epimerase: pyruvate nucleotide- 4-oxo-2-pentenal carrying a with reduced L- a [pyruvate dehydrogenase a [pyruvate dehydrogenase 3-phosphate [DNA] nucleobase HtpX 2-enoyl-[acp] III synthase: transfer quinol protein disulfide 5-deoxy-D-glucuronate disulfide bond ASD06_RS10995 E2 protein] N 6 - E2 protein] N 6 -S- 3'-phosphate 4-hydroxy-3- ASD06_RS09135 cysteine residues enoyl-ACP methylbut-2-enyl methylmalonyl- dihydrolipoyl-L-lysine acetyldihydrolipoyl-L-lysine 5-deoxy- (R)-NADHX reductase diphosphate CoA glucuronate N-acetyl-muramoyl-(L- an sn-glycero-3- L-alanyl-γ-D- an N-terminal- a peptide with a (1->4)- uroporphyrinogen-III a [2-oxoglutarate dehydrogenase E2 a lipid II phosphoenol FabI: fabI 4-hydroxy-3- 6 pyruvate MoO - α reductase: NAD(P)H-hydrate epimerase: mce isomerase: iolB alanyl-γ-D-glutamyl-L- phospho-N-(acyl) glutamyl-L-lysyl- 2 L-methionyl- an N-terminal -D-glucan protein] N -dihydrolipoyl-L-lysine ATP dGDP pyruvate enoyl-ACP methylbut-2-enyl ASD06_RS03770 Pentose Phosphate Pathways epimerase: 2-oxoglutarate ethanolamine D-alanyl-D-alanine molybdopterin glycyl-[protein] 1,4-alpha- N 6 -L-threonylcarbamoyladenosine 37 (R)-methylmalonyl- 5-dehydro-2- lysyl-D-alanyl-D-alanine) L-methionine RS10840 reductase: diphosphate (S)-NADHX ASD06_RS08135 CoA deoxy-D-gluconate dehydrogenase, cofactor glucan -modified tRNA biosynthesis pyruvate, D-alanyl-D-alanine ASD06_RS08065 reductase: pentose phosphate pathway pyruvate D-gluconate E2 component, branching NAD(P)H-hydrate methylmalonyl- phosphate D-alanyl-D-alanine glycerophosphodiester D-alanyl-D-alanine carboxypeptidase/ type I methionyl type I methionyl ASD06_RS03770 IPP dehydrogenase: degradation dihydrolipoamide molybdenum cofactor protein dehydratase: CoA mutase: dikinase: carboxypeptidase/ phosphodiesterase: carboxypeptidase/ D-alanyl-D-alanine- pyruvate aminopeptidase: aminopeptidase: a hexanoyl-[acp] D-glucopyranose thr acetyl-CoAASD06_RS10575 succinyltransferase: sucB guanylyltransferase: GlgB: glgB ASD06_RS03555 ASD06_RS00930 5-dehydro-2-deoxy-D- ASD06_RS13700 D-alanyl-D-alanine- ASD06_RS16355 D-alanyl-D-alanine- endopeptidase: dacB kinase: pyk map map a (1,6)-α-D- 6-phosphate threonylcarbamoyl-AMP D-gluconate ASD06_RS16160 methylmalonyl- gluconate 6-phosphate multifunctional oxoglutarate endopeptidase: dacB glycerophosphodiester endopeptidase: dacB [+ 2 isozymes] [+ 2 isozymes] [+ 2 isozymes] glucosyl-(1,4) beta- glucose-6- synthase: ASD06_RS15685 NADH gluconokinase: RS01945 CoA mutase: decarboxylase/oxoglutarate [+ 2 isozymes] phosphodiesterase: [+ 2 isozymes] -α-glucan ketoacyl- phosphate threonylcarbamoyl-AMP ASD06_RS04425 phosphoenol adenylyl ASD06_RS03120 D-gluconate dehydrogenase thiamine H + ASD06_RS05545 ACP synthase: ASD06_RS01200 diphosphate a N- pyruvate an N-terminal DMAPP dehydrogenase: 6-phosphate pyrophosphate-binding AMP pyruvate γ molybdenum dGTP synthase myo-inositol (L-threonylcarbamoyl)adenylate N-acetyl-muramoyl-(L- L-alanyl- -D- D-ala acetylglucosamine- met glycyl-[protein] met a peptide ASD06_RS06225 succinyl-CoA subunit/dihydrolipoyllysine- cofactor II: fabF biosynthesis alanyl-γ-D-glutamyl- D-ala glutamyl-L- D-ala -N-acetylmuramyl- 6-phospho DHAP sn-glycerol an N- tRNA (adenosine(37)-N6)- 3-oxopropanoate residue succinyltransferase L-lysyl-D-alanine) lysyl-D-alanine (tetrapeptide) a 3-oxooctanoyl- D-glucopyranose D-glucono- 3-phosphate acylethanolamine RS12735 threonylcarbamoyltransferase subunit: ASD06_RS01325 pyrophosphoryl- [acp] 6-phosphate 1,5-lactone complex: tsaD tsaB tsaE Fatty Acid and Lipid Degradation a [2-oxoglutarate dehydrogenase E2 inositol-3- undecaprenol 6-phosphogluconolactonase: protein] N 6 -S-succinyldihydrolipoyl-L-lysine 3-oxoacyl- phosphate 6 37 an N -L-threonylcarbamoyladenine in tRNA β [acyl-carrier- pgl oleate -oxidation synthase: fatty acid β-oxidation I (generic) acetyl-CoA protein] ASD06_RS17030 D-gluconate a mature peptidoglycan (meso 7,8-didemethyl- 3-(D-glyceryl) a peptidoglycan (E)-4-hydroxy-3- an unstable 7,8-dihydrofolate + phosphoenol reductase: 6-phosphate oleate 8-hydroxy-5- -diphospho- NADPH H glycerophosphoserine D-glycero-β-D- a glycyl-[tRNA Ala ] methylbut-2-en- RecA filament- RS11535 Ins(3)P Amino Acid Biosynthesis a (3Z)-alk-3- -diaminopimelate containing) monoglutamate dimer (generic) ATP pyruvate fabG L-histidine biosynthesis Respiration manno-heptose dADP ATP L-arginine biosynthesis I (via L-ornithine) L-lysine biosynthesis I superpathway of branched chain amino acid biosynthesis L-arginine biosynthesis II (acetyl cycle) L-isoleucine superpathway of L-serine decarboxylating 6- enoyl-CoA deazariboflavin 5'-guanosine biotin 1-yl diphosphateflavodoxin- DNA complexDNA a (3R)-3- long-chain fatty 1-phosphate inositol biosynthesis IV and glycine biosynthesis I phosphogluconate dependent repair hydroxyoctanoyl- 2-oxoisovalerate decarboxylation to isobutanoyl-CoA acid--CoA ligase: lytic transglycosylase dihydrofolate glycerophosphodiester lytic monophosphatase: PRPP dehydrogenase: gnd 2-phospho-L- D-tyrosyl-tRNA(Tyr) protein pyruvate N-acetylglutamyl- ASD06_RS01820 domain-containing reductase: phosphodiesterase: transglycosylase (E)-4-hydroxy- [acp] ASD06_RS07410 glu asp thr propanoate 3-phospho-D-glycerate D-ribulose lactate transferase: bifunctional heptose deacylase: biotin--[acetyl-CoA- ATP bifunctional phosphate an [apo BCAA protein: ASD06_RS12900 domain-containing pyruvate 3-methylbut- RecO: Mg 2+ MgtA Mg 2+ acetolactate long-chain fatty 5-phosphate [+ 5 isozymes] a (2E)-2- ASD06_RS02555 ASD06_RS16355 carboxylase] ligase: myo-inositol phosphoribosyltransferase: aspartate kinase: glutamate N- phosphoglycerate dehydrogenase ASD06_RS18375 protein: 7-phosphate ASD06_RS15050 kinase: pyk 2-enyl- a stabilizedrecO bifunctional threonine/serine synthase: ilvN acid--CoA ligase: alpha-ketoacid enoyl-CoA enoyl-CoA dihydrofolate glycerophosphodiester ASD06_RS02830 ASD06_RS15630 acetyltransferase/ dehydrogenase: serA 6 oleoyl-CoA ASD06_RS18375 kinase/heptose diphosphate RecA filament- ASD06_RS06630 dehydratase: ASD06_RS01820 E2 protein] N dehydrogenase hydratase: [+ 2 isozymes] reductase: phosphodiesterase: glutamate N- ASD06_RS00710 3-phosphooxypyruvate ribulose- ribose-5-phosphate 1-phosphate synthase: ispG a (2E)-oct- L-aspartyl-4-phosphate ASD06_RS15800 amino-acid -lipoyl-L-lysine a 2,3,4-saturated long-chain fatty acyl-CoA oxidized 3PG- [+ 2 isozymes] 2-C-methyl-D- DNA complex β acetyltransferase/ N-acetyl-gamma- [+ 5 isozymes] subunit beta: ASD06_RS14170 ASD06_RS14855 ASD06_RS05545 Ala 1-(5-phospho- -D-ribosyl)-ATP acetyltransferase phosphate 3- isomerase: acyl-CoA a 2,3,4- adenyltransferase: a tRNA gly biotinyl-5'- erythritol-2,4- 2-enoyl-[acp] amino-acid threonine (S)-2-acetolactate glutamyl-phosphate propanoyl-CoA phosphoserine ASD06_RS19000 fatty acid acid--CoA ligase:dehydrogenase: a mature peptidoglycan a mature peptidoglycan strand factor 420-0 GMP pyruvate YidD ArgJ: argJ epimerase: ASD06_RS16930 dehydrogenase: saturated (3R)-3- ASD06_RS13810 dATP adenylate cyclodiphosphate ammonia-lyase: reductase: transaminase: ASD06_RS15230ASD06_RS16215 with (L-alanyl-γ-D-glutamyl- (non-reducing terminus) GlcNAc-1,6- enoyl-ACP phosphoribosyl-ATP acetyltransferase aspartate- ketol-acid rpe alpha-ketoacid ASD06_RS10880 5,6,7,8- a lipid II amino-acid N- 2-oxoacid:ferredoxin ribose-5-phosphate [+ 12 isozymes] a 2,3,4- hydroxyacyl-CoA meso-2,6-diaminopimeloyl- NADP + sn-glycerol anhydro-MurNAc- diphosphatase: ArgJ: argJ semialdehyde ASD06_RS03480 acetylglutamate ASD06_RS12320 ASD06_RS13980 dehydrogenase [+ 5 isozymes] a 2,3,4-saturated ser reductase reductoisomerase: acetyltransferase: oxidoreductase isomerase: [+ 12 isozymes] saturated (3S)-3- tetrahydrofolate 3-phosphate ADP-D-glycero-β- ASD06_RS06635 dehydrogenase: kinase: argB fatty acyl CoA D-alanine) tetrapeptide pentapeptide FabI: fabI amino-acid N- (2Z)-2-aminobut- ilvC ASD06_RS09385 D-xylulose ASD06_RS10985 subunit beta: (2E,9Z)- hydroxyacyl-CoA D-manno-heptose ASD06_RS04325 gln N-acetyl-L-glutamate subunit beta: O-phospho-L-serine dihydrolipoyl enoyl-ACP β acetyltransferase: 2-enoate glu N-acetyl-L-glutamate 5-phosphate ASD06_RS17345 octadecenoyl-CoA 1-(5-phospho- -D-ribosyl)-AMP (2R)-2,3-dihydroxy- 5-semialdehyde ASD06_RS08890 dehydrogenase: 3-hydroxyacyl-CoA reductase: ASD06_RS09385 L-aspartate 4- 3-methylbutanoate D-ribose 5- an [apo BCAA an [apo BCAA dehydrogenase enoyl-CoA dehydrogenase: RS10795 glutamine- acetylornithine lpdA a nascent peptidoglycan 7,8-didemethyl- enolpyruvoyl- an (R)-2- β-D-fructofuranose an N-terminal- a peptide with a [protein]-L- semialdehyde 2-oxobutanoate phosphoserine 6 + a D-aspartyl- O-phospho- ASD06_RS08065 phosphoribosyl-AMP N-acetyl-L- dihydroxy-acid phosphate dehydrogenase E2 protein] N -S-[2- hydratase: coenzyme A ASD06_RS17310 8-hydroxy-5- 2-diphospho- glu a (6S)-5- NADPH NAD L-methionyl-L- cys hydrolyzing transaminase: phosphatase SerB: serB (meso-DAP containing) halocarboxylate 1-phosphate asp an N-terminal methionine cyclohydrolase: hisI bifunctional E2 protein] N 6 - methylpropanoyl]dihydrolipoyl- ASD06_RS14170 [tRNA ] L-homoserine glutamate 4-hydroxy- dehydratase: carbamoyl- ASD06_RS12305 acetolactate transketolase: deazariboflavin 5'-guanosine formyltetrahydrofolate alanyl-[protein] L-alanine peptide- an octanoyl-[acp] β 2-iminobutanoate glutamate N- a 2,3,4-saturated a 2,3,4-saturated 1-(5-phospho- -D-ribosyl)- tetrahydrodipicolinate ilvD ASD06_RS16935 dihydrolipoyl-L-lysine L-lysine (S)-3-hydroxy-(9Z) 3-ketoacyl- methionine phosphate acetyltransferase/ synthase: ilvN ser fatty acyl CoA 3-oxoacyl-CoA lytic transglycosylase 5-[(5-phosphoribosylamino) acetylglutamate synthase: dapA CoA thiolase: HAD family NAD(P)(+) fructose- a reduced 3-methyl-2- synthase: ASD06_RS00710 [+ 2 isozymes] -octadecenoyl-CoA 2-phospho-L- bifunctional D-tyrosyl-tRNA(Tyr) type I methionyl cystathionine aminopeptidase (S)-S-oxide beta- kinase: argB (2S,4S)-4- amino-acid ASD06_RS06105 domain-containing hydrolase: transhydrogenase bisphosphate methylideneamino]imidazole- oxobutanoate carB carA 3-hydroxyacyl-CoA lactate transferase: deacylase: gamma-synthase: reductase H O c-type ketoacyl- hydroxy-2,3,4,5- acetyltransferase (S)-2-aceto-2- serine D-sedoheptulose D-glyceraldehyde protein: ASD06_RS17950 folylpolyglutamate (Re/Si-specific): aldolase: aminopeptidase: N: pepN 2 cytochrome 4-carboxamide N-acetylglutamyl- superpathway of L-cysteine dehydrogenase: ASD06_RS02555 ASD06_RS15050 ASD06_RS03455 MsrA: msrA cytochrome ACP tetrahydrodipicolinate ArgJ: argJ hydroxybutanoate hydroxymethyltransferase: 7-phosphate 3-phosphate ASD06_RS18375 synthase/ ASD06_RS15750 map [+ 2 isozymes] a protein-L- c oxidase an oxidized bifunctional 1-(5- 2-isopropylmalate branched-chain carbamoyl phosphate L-ornithine biosynthesis (mammalian) 2-oxo acid ASD06_RS17310 HAD family ASD06_RS17155 synthase phosphate 4-hydroxy- 2-oxobutanoate ASD06_RS16480 [+ 2 isozymes] dihydrofolate [+ 2 isozymes] methionine- O c-type phosphoribosyl)-5-((5- hydrolase: ASD06_RS15755 class II fructose- 2 II: fabF synthase: leuA amino acid N-acetyl-L-ornithine dehydrogenase 3-oxo-(9Z)- synthase: (S)-S-oxide cytochrome N-acetyl-gamma- tetrahydrodipicolinate serine transaldolase: tal dehydro ASD06_RS05810 ASD06_RS15760 phosphoribosylamino) acetolactate aminotransferase: met subunit E2: octadecenoyl-CoA bisphosphate asp RS17375 glutamyl-phosphate reductase: hydroxymethyltransferase: a mature peptidoglycan factor 420-0 ASD06_RS03970 tRNA D-aspartate L-cystathionine ala a peptide a 3-oxodecanoyl- methylideneamino)imidazole- synthase: ilvN ASD06_RS00675 (R)-2,3-dihydroxy- ASD06_RS17175 acetyl-CoA a nascent peptidoglycan GMP aldolase: fbaA an N-terminal L- reductase: ASD06_RS12960 (2S)-2-isopropylmalate ASD06_RS01195 3-ketoacyl- γ met [acp] 4- carboxamide isomerase/ ASD06_RS00710 3-methylpentanoate methionine D-erythrose with (L-alanyl- -D-glutamyl- (meso-DAP containing) alanyl-[protein] L-tryptophan biosynthesis F6P 2-oxo acid CoA thiolase: an (S)-2- + ASD06_RS12320 (S)-2,3,4,5- 4-phosphate meso-2,6-diaminopimeloyl- with GlcNAc terminus a halide anion NADH NADP 3-oxoacyl- phosphoribosylanthranilate (S)-2-aceto-2- 3-isopropylmalate adenosyltransferase: a (6S)-5- N-acetyl-L- dihydroxy-acid gly dehydrogenase ASD06_RS00985 hydroxycarboxylate D-glyceraldehyde isomerase PriA: priA tetrahydrodipicolinate val ornithine ASD06_RS06725 transketolase: D-alanine) tetrapeptide formyltetrahydrofolate DHAP [acyl-carrier- glutamate 5- hydroxybutanoate dehydratase: dehydratase: ilvD subunit E2: 3-ketoacyl- 2,3,4,5- carbamoyltransferase: gln ASD06_RS16935 protein] phosphoribulosylformimino- semialdehyde ketol-acid leuD leuC chorismate ASD06_RS17350 CoA thiolase: tetrahydropyridine- argF (3S)-3-methyl-2- SAM [+ 2 isozymes] RS07625 reductase: AICAR-phosphate acetylornithine reductoisomerase: ASD06_RS06105 hydrogencarbonate 2,6-dicarboxylate N- 2-isopropylmaleate oxopentanoate TCA cycle IV (2-oxoglutarate decarboxylase) TCA cycle 5-amino-5-(4- 7,8-didemethyl- L-lactyl-2- an (S)-2- a protein-L- fabG transaminase: ilvC D-glyceraldehyde glycerophosphoglycerol uroporphyrinogen-III 2-oxoglutarate isochorismate NADH anthranilate synthase hydroxybenzyl)- SAM 8-hydroxy-5- diphospho- halocarboxylate fMet methionine- a (3R)-3- ASD06_RS12305 succinyltransferase: branched-chain 3-phosphate (7Z)-hexadecenoyl-CoA dITP GTP 2-phospho- imidazole glycerol glutamine- (R)-2,3-dihydroxy- 3-isopropylmalate component I: L-proline biosynthesis 6-(D-ribitylimino) deazariboflavin 5'-guanosine uroporphyrinogen-III (R)-S-oxide hydroxydecanoyl- dapD L-arginine amino acid oxaloacetate Amine and Polyamine Degradation L-lactate peptide- phosphate synthase hydrolyzing N-acetyl-L- 3-methylpentanoate dehydratase: ASD06_RS06480 I (from L-glutamate) -5,6-dihydrouracil C-methyltransferase: RdgB/HAM1 family non- [acp] N-succinyl-2-amino- aminotransferase: acyl-CoA NAD(+) methionine subunit HisH: hisH carbamoyl- ornithine dihydroxy-acid leuD leuC degradation I HAD family glycerophosphodiester cobA 2-succinyl-5- canonical purine NTP ASD06_RS00675 dehydrogenase: 2-phospho-L- formylmethionine (R)-S-oxide RS00050 6-ketopimelate (arginase pathway) SAH superpathway of 4- hydrolase: phosphodiesterase: enolpyruvyl- pyrophosphatase: rdgB diphosphatase: imidazole glycerol phosphate dehydratase: (2R,3S)-3- L-citrulline glu citrate synthase: lactate transferase: bifunctional 2-phospho-L-lactate deformylase: succinyldiaminopimelate anthranilate PRPP ASD06_RS10880 4-aminobutanoate allantoin degradation putrescine degradation IV bifunctional FO ASD06_RS17950 ASD06_RS05545 nudC reductase phosphate synthase synthase: ilvD isopropylmalate aminobutanoate degradation ASD06_RS02555 uroporphyrinogen-III 6-hydroxy-3- nucleotide guanylyltransferase: ASD06_RS03340 arg ile glutamate 5-kinase: ASD06_RS10005 [+ 12 isozymes] degradation III to ureidoglycolate II biosynthesis MsrB: msrB subunit HisF: hisF carB carA transaminase: adenosylhomocysteinase: Metabolic Clusters HAD family glycerophosphodiester cyclohexene-1- pyrophosphohydrolase: cofC a [protein]-L- a (2E)-dec- (3S)-3-methyl-2- 3-isopropylmalate argininosuccinate ASD06_RS04085 malate dehydrogenase: protein CofGH: C-methyltransferase/ β ASD06_RS10000 ASD06_RS02480 γ-L-glutamyl (2E,7Z)- 4-aminobutanoate (ammonia producing) putrescine hydrolase: phosphodiesterase: carboxylic-acid ASD06_RS11120 reduced - methionine 2-enoyl-[acp] carbamoyl oxopentanoate dehydrogenase: synthase: argG anthranilate (S)-malate ASD06_RS07630 citrate 4-aminobutanoate ASD06_RS01875 uroporphyrinogen- L-ornithine N-succinyl-L,L-2,6- 5-phosphate hexadecenoyl-CoA 4-aminobutyrate- (S)-(+)-allantoin oxidized ASD06_RS05810 ASD06_RS16355 synthase: menD nicotinamide D- D-erythro-1-(imidazol-4- phosphate branched-chain ASD06_RS00685 phosphoribosyltransferase: trpD N-end rule pathway I (prokaryotic) III synthase: dIMP L-lactyl-2- formate met AMP enoyl-ACP AICAR diaminopimelate L-ornithine enoyl-CoA -2-oxoglutarate 4-aminobutyrate- factor 420-0 GMP ribonucleotide RS02255 yl)-glycerol 3-phosphate amino acid (2S)-2-isopropyl- L-arginino-succinate L-homocysteine ser glutamate-5- class II fumarate hydratase: 7,8-didemethyl- ASD06_RS09135 diphospho- reductase leucyl/phenylalanyl- hydratase: transaminase: gabT -2-oxoglutarate 2-succinyl-5-enolpyruvoyl- succinyl- aminotransferase: 3-oxosuccinate semialdehyde ASD06_RS03690 aconitate hydratase 5'-deoxyadenosine 8-hydroxy-5- an (S)-2- 5'-guanosine FabI: fabI imidazoleglycerol- ornithine ornithine- argininosuccinate N-(5-phosphoribosyl)-anthranilate tRNA--protein ASD06_RS14170 transaminase: met a halide anion glycerol sn-glycerol precorrin-2 diaminopimelate dehydrogenase: AcnA: acnA 4-aminobutyrate- allantoate 6-hydroxy-3-cyclohexene- phosphate carbamoyltransferase: ASD06_RS00675 -oxo-acid fumarate hydratase: gabT 4-aminobutanal deazariboflavin hydroxycarboxylate 3-phosphate enoyl-ACP desuccinylase: lyase: argH cystathionine ASD06_RS04095 transferase: (S)-3-hydroxy-(7Z) -2-oxoglutarate 1-carboxylate dehydratase argF bifunctional 1-(5- ASD06_RS03725 a [protein] reductase: ASD06_RS10025 transaminase: beta-synthase: an N-terminal ASD06_RS11590 -hexadecenoyl-CoA transaminase: gabT 4-aminobutyrate- allantoate RS14370 HisB: hisB ile phosphoribosyl)-5-((5- L-glutamate-5- fumarate cis-aconitate N-terminal L- ASD06_RS08065 4-methyl-2- rocD arg ASD06_RS03375 aconitate hydratase arginyl-[protein] 3-hydroxyacyl-CoA succinate semialdehyde -2-oxoglutarate amidohydrolase: gamma- phosphoribosylamino) semialdehyde leucyl-L-arginine a [ribosomal a carboxy- sn-glycero-3- a mycothiol a negatively (3R,5S)-3- RS10950 3-(imidazol-4-yl)-2- L,L-diaminopimelate oxopentanoate L-glutamate-5- dehydrogenase: transaminase: ASD06_RS17625 aminobutyraldehyde a sulfurated MoO - oxaloacetate a uracil in DNA acetyl-CoA propanoyl-CoA AcnA: acnA protein S12] 2 adenylated- a decanoyl-[acyl- asp L-citrulline methylideneamino)imidazole- NAD-dependent GTP cys phosphoethanolamine ITP S-conjugate supercoiled DNA a protein hydroxy-1- oxopropyl phosphate semialdehyde ASD06_RS17310 gabT dehydrogenase: [sulfur carrier] 89 molybdopterin carrier protein] branched-chain 4- carboxamide isomerase/ succinate (S)-ureidoglycine L-aspartate molybdopterin [ThiS sulfur- DNA zinc-dependent pyrroline-5- diaminopimelate L-cystathionine ATP biosynthesis leucyl/phenylalanyl- succinate- succinate- ASD06_RS13215 1-pyrroline cofactor histidinol-phosphate amino acid L-glutamate phosphoribosylanthranilate 3-oxo-(7Z)- semialdehyde carrier protein] topoisomerase metalloprotease: carboxylatepyrroline-5- beta- epimerase: tRNA--protein semialdehyde semialdehyde glycerophosphodiester uracil-DNA acetyl-CoA C- mycothiol transaminase: hisC argininosuccinate L-phenylalanine aminotransferase: gamma- isomerase PriA: priA hexadecenoyl-CoA IV subunit A: ASD06_RS09640 carboxylate RS08315 ketoacyl- ASD06_RS12705 (S)-1-pyrroline- transferase: dehydrogenase: dehydrogenase 30S ribosomal phosphodiesterase: glycosylase: acetyltransferase: conjugate histidinol-phosphate synthase: argG biosynthesis I ASD06_RS00675 semialdehyde succinate D-threo-isocitrate a [protein] 3-ketoacyl- 4-aminobutanoate molybdenum cofactor phosphoenolpyruvate ASD06_RS05280 reductase: ACP 1-(2-carboxyphenylamino)-1- 5-carboxylate NADP-dependent an N-terminal ASD06_RS11590 ASD06_RS13110 (NADP(+)): protein S12 cysteine ASD06_RS16355 ASD06_RS03330 ASD06_RS00985 amidase zinc-dependent RS17885 transaminase: dehydrogenase: ADP N-terminal L- CoA thiolase: guanylyltransferase: carboxykinase (GTP) proC synthase meso-diaminopimelate deoxy-D-ribulose 5-phosphate isocitrate dehydrogenase: ASD06_RS07980 methylthiotransferase desulfurase: Mca: mca type I DNA metalloprotease: L-arginino- leu pyrroline-5- V-type ATP succinate-semialdehyde L-lysyl-[protein] NAD-dependent ASD06_RS16160 glycerophosphodiester : ASD06_RS15865 uracil-DNA [+ 3 isozymes] II: fabF ASD06_RS12405 chorismate pruA L-methionine biosynthesis III ASD06_RS07615 leucyl-L-lysine ASD06_RS00985 succinate (S)-ureidoglycolate putrescine degradation I RimO: rimO ASD06_RS00795 topoisomerase: ASD06_RS02080 Hyp succinate L-homoserine indole-3-glycerol phosphate cys carboxylate synthase subunit B: dehydrogenase (NADP(+) succinate- phosphodiesterase: glycosylase: a 3- chorismate mutase: 3-ketoacyl- topA L-histidinol phosphate biosynthesis diaminopimelate L-glutamate synthase TrpC: trpC reductase: ASD06_RS12100 ): ASD06_RS07980 semialdehyde ASD06_RS05545 ASD06_RS05095 a peptide oxododecanoyl- argininosuccinate ASD06_RS12010 CoA thiolase: bis(guanylyl 3-oxopentanoyl- a relaxed DNA RS14015 decarboxylase: lysA gamma- L-homoserine proC dehydrogenase: putrescine a [ribosomal a thiocarboxylated- phosphoenolpyruvate GlcN-Ins a mercapturate lyase: argH chorismate F0F1 ATP synthase: ASD06_RS06105 5'-deoxyadenosine an unsulfurated molybdopterin) CoA [acp] semialdehyde (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate succinate semialdehyde 2-oxoglutarate ASD06_RS01785 met protein S12]-3- ala [ThiS sulfur- IDP histidinol- mutase: aroH ASD06_RS01125 cofactor AMP RS02575 3-oxoacyl- asp dehydrogenase: pro methylsulfanyl- [sulfur carrier] carrier protein] sn-glycerol an apyrimidinic uracil pro phosphatase: hisN lys L-tyrosine homoserine O- NADPH repair (eukaryotes) (5Z)-tetradecenoyl-CoA ethanolamine [acyl-carrier- prephenate atpD urea degradation II 89 site in DNA arg aspartate kinase: pruA acetyltransferase: tryptophan synthase: L-selenocysteine succinate 4-aminobutanal L-aspartate 3-phosphate protein] biosynthesis I ASD06_RS01145 ASD06_RS15630 acyl-CoA histidinol prephenate ASD06_RS05225 ASD06_RS06445 trpB biosynthesis I (bacteria) ASD06_RS01150 NADPH reductase: L-aspartyl- glu L-cysteine biosynthesis I multifunctional oxoglutarate urea gamma- dehydratase: chorismate O-acetyl-L- ASD06_RS01155 dehydrogenase: RS15235 fabG 4-phosphate ser decarboxylase/oxoglutarate urease: aminobutyraldehyde a [2-oxoglutarate- a [prokaryotic an (S)-2- a 1-acyl-2- histidinol ASD06_RS12025 indole sec ASD06_RS16215 a sulfurated aci-nitroethane protoheme RNA an unfolded a (3R)-3- an L-prolyl- chorismate mutase: homoserine hydrogen sulfide selenide ser a tRNA ASD06_RS01160 SAM dehydrogenase ubiquitin-like protein] arachidonoyl- cys L-homocysteine glu ala dehydrogenase: hisD dehydrogenase thiamine ASD06_RS14755 dehydrogenase: a [protein]-L-lysine ATP halocarboxylate protein RS02680 aspartate- prephenate ASD06_RS12010 ser atpE atpB [+ 12 isozymes] [sulfur carrier] 6 a tRNA precursor hydroxydodecanoyl- [RedO prolyl- pyrophosphate-binding ureA ASD06_RS13215 E2 protein] N - C-terminal L-glutamate sn-glycerol chaperonin semialdehyde dehydratase: chorismate selenide, (2E,5Z)- CTP CTP [acp] carrier protein] histidinal tryptophan synthase: ATP subunit/dihydrolipoyllysine- ammonium octanoyl-L-lysine 3-phosphate GroEL: groL pheA water serine--tRNA tetradecenoyl-CoA HAD family nitronate deferrochelatase/ dehydrogenase: mutase: aroH ASD06_RS06445 trpB serine O- (R)-NADPHX NAD(P)H-hydrate 4-aminobutanoate cystathionine glutamate-- ribonuclease chaperonin dikinase ligase: serS residue succinyltransferase Pup--protein hydrolase: monooxygenase: peroxidase EfeB: efeB ASD06_RS04325 3-phenyl-2- prephenate acetyltransferase: cysE epimerase: lipoyl CCA tRNA PH: rph histidinol subunit: ASD06_RS01325 ligase: pafA phosphatidate beta-synthase: cysteine ligase: GroEL: groL PstC oxopropanoate SelD: selD ASD06_RS08135 enoyl-CoA synthase: nucleotidyltransferase: ASD06_RS17950 ASD06_RS07805 ferrochelatase: a 1H-pyrrole- dehydrogenase: hisD L-aspartate 4- prephenate L-homocysteine cytidylyltransferase: ASD06_RS03375 ASD06_RS05440 a protein a (2E)-dodec- trp hydratase: lipA ASD06_RS16890 HAD family 2-nitropropane ASD06_RS07415 ArsB 2-carbonyl- semialdehyde dehydrogenase: selenophosphate an L-seryl-[tRNA sec ] O-acetyl-L-serine (S)-NADPHX ASD06_RS13280 2-enoyl-[acp] hydrogen sulfide ASD06_RS14170 hydrolase: dioxygenase: a nucleoside [RedO prolyl- ASD06_RS05340 methionine methionine (3E,5Z)-tetradeca- a [2-oxoglutarate N6-([prokaryotic RNA his homoserine ASD06_RS05810 ASD06_RS16260 γ-L-glutamyl- diphosphate enoyl-ACP 3-(4- synthase: synthase: NAD(P)H-hydrate 3,5-dienoyl-CoA 5'-deoxyadenosine an unsulfurated ubiquitin-like protein]- a tRNA carrier protein] dehydrogenase: met dehydrogenase a CDP-1-acyl- Fe 2+ protoporphyrin IX L-cystathionine D-alanine dehydratase: (S)-3-hydroxy-(5Z) [sulfur carrier] γ-L-glutamyl)- reductase L-threonine ASD06_RS01255 phe hydroxyphenyl) metH metH L-seryl-tRNA(Sec) bifunctional o- E2 protein] N 6 containing a 2-arachidonoyl- ASD06_RS03555 -tetradecenoyl-CoA RS13510 FabI: fabI malonyl-CoA biosynthesis pyruvate selenium acetylhomoserine/o- -lipoyl-L-lysine [protein]-L-lysine 3' CCA end a (2R)-2- glycerol methionine methionine 3-hydroxyacyl-CoA a halide anion acetaldehyde nitrite enoyl-ACP L-homoserine ammonia assimilation cycle III transferase: acetylserine sulfhydrylase: Aromatic Compound Degradation hydroxy fatty acid RS02880 a [RedX acyl- synthase: synthase: NADPH (3E,5Z)- dehydrogenase: reductase: L-homoserine ASD06_RS00775 ASD06_RS00775 ASD06_RS04420 ASD06_RS05220 carrier protein]- superpathway of L- tetradecadienoate ASD06_RS17310 ASD06_RS08065 ammonium cysteine synthase A: cysK α trans,octacis a [TusE sulfur DNA with adenine:7,8- (1H-pyrrole- asparagine biosynthesis homoserine kinase: L-glutamate 3-oxo-(5Z)- phenylacetate GDP- -D- an (R)-2- a glucosylated parathion degradation a uridine 34 in tRNA 37 2-carbonyl) ASD06_RS01245 biosynthesis III alanine tyr met an L-selenocysteinyl- degradation I (aerobic) mannose -decaprenyl carrier protein]-S DMAPP an adenosine dihydro-8- a tRNA precursor N-ethylglycine glycogenin sec tetradecenoyl-CoA ATP halocarboxylate a dodecanoyl-[acp] a malonyl-[RedN] O-phospho- racemization glu [tRNA ] in tRNA XTP ATP 1,4-alpha- RS14795 malonyl-CoA -L-cysteine 2-oxoglutarate glutamine phosphate -sulfanylcysteine ammonium hydrogencarbonate oxoguanine mismatch asp cys 3-ketoacyl- RdgB/HAM1 family non- L-homoserine L-alanine 2-oxoglutarate glutamate synthetase: coenzyme A phenylacetate parathion adenylyl cyclase: glucan RS07340 glutamate CoA thiolase: polyprenol HAD family canonical purine NTP glycine branching threonine biosynthesis III ala synthase large ASD06_RS00660 tRNA (adenosine(37)-N6) A/G-specific ASD06_RS07240 synthase large ASD06_RS00985 tRNA 2- hydrolase: ribonuclease D: pyrophosphatase: rdgB oxidase synthase: subunit: gltB monophosphomannose -dimethylallyltransferase protein asparagine asparagine alanine racemase: imidazole [+ 2 isozymes] phenylacetate-- phosphotriesterase: thiouridine(34) carbamate kinase: adenine ASD06_RS07290 adenylate/guanylate ThiO: thiO a dodecanoyl- a malonyl-[RedL a 3-oxo-3-(1H subunit: gltB (3Z)-dodec- synthase: ASD06_RS17950 MiaA: miaA nucleotide GlgB: glgB synthase synthase ASD06_RS01250 cys ASD06_RS08130 glycerol CoA ligase: paaF ASD06_RS03635 synthase ASD06_RS06520 glycosylase: cyclase domain- [RedQ acyl- polyketide -pyrrol-2-yl) glu 3-enoyl-CoA ASD06_RS05565 HAD family pyrophosphohydrolase: a glycogen RS11940 (glutamine- (glutamine- SufS family cysteine D-ala phosphate MnmA: mnmA ASD06_RS09355 containing protein: carrier protein] synthase] propanoyl-[RedN] thr hydrolase: 6 ASD06_RS11120 hydrolyzing) hydrolyzing) desulfurase: sufS ammonium synthase gln peptidoglycan biosynthesis I (meso-diaminopimelate containing) Cell Structure Biosynthesis trans,octacis- N -(3-methylbut- a nucleoside 5'- ASD06_RS02820 ethylamine glyoxylate RS03095 : asnB : asnB phenylacetyl-CoA diethylthiophosphate 4-nitrophenol ASD06_RS05810 a tRNA XMP cyclic-AMP cysteine desulfurase: decaprenylphospho- 34 carbamoyl 2-en-1-yl)- subunit HisF: hisF GDP a 2-thiouridine a [TusE sulfur carrier an apurinic site monophosphate ASD06_RS00795 UDP-N-acetyl-α-D-glucosamine (2E)-dodec- β phosphate adenosine 37 [+ 8 isozymes] phenylacetate- -D-mannose in tRNA protein]-L-cysteine adenine within DNA 4-hydroxy- ala 2-enoyl-CoA a (2R)-2- in tRNA UDP-N-acetylglucosamine CoA oxygenase/ a halide anion a 3-oxotetradecanoyl- 2,2'-bipyrrole- asn asn hydroxy fatty acid 1-carboxyvinyltransferase: enoyl-CoA reductase: RS04875 [RedL polyketide 5-methanol Polymeric Compound hydratase: paaA paaB RS11540 synthase] glu murA Degradation ASD06_RS14170 paaC paaJ paaK diethylphosphate UDP-N-acetylglucosamine a [DNA]-3'- + a 5'-phospho- Nα,Nε-diacetyl-lysyl- a 2-oxo α 2-(1,2-epoxy-1,2- cob(II)alamin NAD O-succinyl-L- a nucleoside O-ureido-L- -amylose 1-carboxyvinyltransferase: (S)-3- glycogen degradation II hydroxyl [DNA] cys D-alanyl-D-alanine carboxylate L-ornithine RNA asp sarcosine a protein 4-hydroxy-2,2'- dihydrophenyl) ATP homoserine triphosphate ITP 1,4-alpha- murA hydroxydodecanoyl-CoA homoserine ATP-dependent 5-undecyl-1,2- bipyrrole-5- acetyl-CoA RdgB/HAM1 family non- glucan 3-hydroxyacyl-CoA a glycogen Clp protease: RS10190 dihydropyrrol- carbaldehyde UDP-N-acetyl-α-D-glucosamine-enolpyruvate DNA ligase: D-alanyl-D-alanine canonical purine NTP branching dehydrogenase: cystathionine ornithine- DNA-directed ASD06_RS03920 3-one chlorpyrifos degradation cob(I)yrinic acid ASD06_RS09480 carboxypeptidase/ argininosuccinate pyrophosphatase: rdgB glycine oxidase protein RS13605 UDP-N-acetylmuramate ASD06_RS17310 paraoxon degradation gamma-synthase: -oxo-acid RNA polymerase: ASD06_RS03925 a,c-diamide [+ 5 isozymes] D-alanyl-D-alanine- synthase: argG ThiO: thiO dehydrogenase: ASD06_RS03455 transaminase: ASD06_RS08460 nucleotide GlgB: glgB 3-oxododecanoyl-CoA 2-oxepin-2(3H)- adenosyltransferase: endopeptidase: dacB clpX 4-methoxy- ASD06_RS08600 chlorpyrifos rocD rpoB pyrophosphohydrolase: amylopectin ylideneacetyl-CoA paraoxon α ASD06_RS01115 a peptide 2,2'-bipyrrole- ala phosphotriesterase: an -limit dextrin [+ 2 isozymes] ASD06_RS11120 2-undecylpyrrole glu UDP-N-acetyl-α-D-muramate 3-ketoacyl- [DNA] NMN [+ 2 isozymes] RS18070 5-carbaldehyde ASD06_RS03635 succinate canavaninosuccinate IMP glyoxylate methylamine CoA thiolase: phosphotriesterase: 4-alpha- adenosylcobalamin AMP L-cystathionine a proteinogenic L-glutamate-5- α ε RS15215 glutamate racemase: UDP-N-acetylmuramate- ASD06_RS06105 diethylthiophosphate ASD06_RS03635 glucanotransferase: triphosphate N ,N -diacetyl- amino acid semialdehyde 3-oxo-5,6- D-ala RNA ASD06_RS10645 -L-alanine ligase: malQ lysyl-D-alanine decanoyl-CoA didehydrosuberyl- ASD06_RS12485 a debranched CoA semialdehyde 4-nitrophenol undecylprodigiosin D-glt acyl-CoA diethylphosphate α-limit dextrin RS13180 UDP-N-acetyl-α-D-muramoyl-L-alanine dehydrogenase: adenine 2503 a pentaglycine cross- an N-formyl-L- a 2'- an N-terminal- methyl β-D-glucoside a (1->4)- a protein with an alkylated DNA a folate salicyl-CoA diethylphosphate in 23S rRNA methionylaminoacyl- deoxyribonucleoside L-methionyl-L- 6-phosphate thr α-D-glucan NhaA ASD06_RS10880 bridge of peptidoglycan LAXTG motif [DNA] UDP-N-acetylmuramoyl- 3-oxo-5,6- tRNA 5'-triphosphate cysteinyl-[protein] dihydrofolate bifunctional 1,4-alpha- [+ 12 isozymes] didehydrosuberyl- α reductase: threonine/serine glucan L-alanine--D-glutamate peptidoglycan maturation (meso-diaminopimelate containing) -D- salicylyl-CoA CoA D-glucopyranose 23S rRNA DNA-3- 6-phospho-beta- ASD06_RS14855 dehydratase: branching streptorubin B ligase: ASD06_RS12500 (2E)-dec-2-enoyl-CoA glucopyranose class E sortase: peptide DNA polymerase type I methionyl 5-hydroxylase/ 3-oxo-5,6- (adenine(2503)-C(2) methyladenine glucosidase: ASD06_RS15800 protein lipid II (meso 1-phosphate ASD06_RS16635 deformylase: III subunit aminopeptidase: dihydrofolate oxidoreductase: RS17905 α )-methyltransferase glycosylase: ASD06_RS14560 threonine meso-diaminopimelate UDP-N-acetyl- -D-muramoyl- diaminopimelate containing) enoyl-CoA dehydrosuberyl- ROK family def reductase: ASD06_RS05730 GlgB: glgB Carbohydrate Biosynthesis RlmN: rlmN gamma and tau: ASD06_RS12275 map RS14105 L-alanyl-D-glutamate hydratase: CoA thiolase: alpha-D-glucose glucokinase: ASD06_RS12900 ammonia-lyase: a protein with LAXT ASD06_RS15645 [+ 2 isozymes] gentisyl-CoA starch ASD06_RS14170 ASD06_RS14135 phosphate-specific ASD06_RS11440 a peptide with an β-D-glucose ASD06_RS03480 D-ala UDP-N-acetylmuramoyl- carboxyl end attached [+ 8 isozymes] a DNA containing MeOH a 7,8-dihydrofolate 2-oxobutanoate gluconeogenesis I (S)-3- phosphoglucomutase: 2503 N-terminal glycine a L-methionylaminoacyl- an alkylated 6-phosphate glycogen biosynthesis III (from α-maltose 1-phosphate) trans-2,3- ROK family a 2-methyladenine 5'-deoxyadenosine to a pentaglycine cross- formate trehalose biosynthesis II L-alanyl-D-glutamate-- a nascent peptidoglycan met tRNA an apurinic/ an N-terminal L- γ hydroxydecanoyl-CoA dehydroadipyl-coA ASD06_RS00910 glucokinase: in 23S rRNA nucleobase 2, 6-diaminopimelate with (L-alanyl- -D-glutamyl- bridge of peptidoglycan apyrimidinic site met cysteinyl-[protein] RS12825 (S)-malate D-glucopyranose glycogen biosynthesis I (from ADP-D-Glucose) D-alanine--D-alanine 3-hydroxyacyl-CoA enoyl-CoA [+ 2 isozymes] ASD06_RS11445 [DNA] α D-glucopyranose ligase: ASD06_RS18930 meso-2,6-diaminopimeloyl-D- 6-phosphate ADP- -D-glucose ADP-α-D-glucose ligase: ASD06_RS00465 dehydrogenase: hydratase: RS06395 D-glucopyranose 6-phosphate alanyl-D-alanine) pentapeptide UDP-N-acetyl-α-D-muramoyl-L-alanyl- ASD06_RS17310 ASD06_RS14170 malate 6-phosphate D-alanyl-D-alanine (3S)- trehalose-6- γ-D-glutamyl-meso-2,6-diaminopimelate D-alanyl-D-alanine penicillin-binding a 2-oxo a methylated 34 a thiocarboxylated a 2'- (2S)- hydrogen 6-O-trans- dehydrogenase: 3-oxodecanoyl-CoA a uridine a peptide with a a ribonucleoside [DNA] A(H2) alpha-D-glucose protein 2: hydroxyadipyl- 2-oxoglutarate nucleobase [SAMP] C- deoxyribonucleoside peroxide methoxy-mycolyl- a protein ASD06_RS07630 phosphate carboxypeptidase/ methyl parathion degradation carboxylate in tRNA [DNA] leader sequence 5'-monophosphate ethylmalonyl-CoA phosphate-specific UDP-N-acetylmuramoyl- CoA within DNA terminal glycine 5'-triphosphate DNA polymerase methylmalonyl- trehalose 6- RS12480 trehalose-6- synthase: D-alanyl-D-alanine- ASD06_RS16615 a mature peptidoglycan with 3-ketoacyl- bifunctional ATP- phosphoglucomutase: tripeptide--D-alanyl- γ 3-hydroxyacyl-CoA III subunit CoA epimerase: phosphate pyruvate ASD06_RS14895 endopeptidase: dacB [+ 3 isozymes] (L-alanyl- -D-glutamyl-meso- CoA thiolase: metallophosphatase/ trehalose- dependent zinc oxaloacetate phosphate ASD06_RS00910 dehydrogenase: 2-oxoacid:ferredoxin catalase/ D- alanine ligase: [+ 2 isozymes] 2,6-diaminopimeloyl-D-alanyl- ASD06_RS06105 methyl parathion alpha-ketoglutarate- tRNA 2- DNA polymerase gamma and tau: ASD06_RS10995 synthase: ASD06_RS17310 D-glucopyranose oxidoreductase signal 5'-nucleotidase: peroxidase phosphatase: metalloprotease [+ 2 isozymes] α,α-trehalose ASD06_RS12510 a nascent peptidoglycan D-alanine) pentapeptide dependent thiouridine(34) III subunit ASD06_RS15645 methylmalonyl- ASD06_RS14895 UDP-N-acetyl-D- α subunit beta: peptidase I: lepB ASD06_RS15155 HPI: katG otsB FtsH: hflB phosphoenolpyruvate -D- 6-phosphate a nascent peptidoglycan with D,D cross-links (meso- octanoyl-CoA 6-phosphate dioxygenase AlkB: synthase [+ 3 isozymes] CoA trehalose- alpha-D-glucose glucosamine biosynthesis I α 3-oxoadipyl-CoA phosphotriesterase: ASD06_RS08890 gamma and tau: [+ 2 isozymes] bifunctional a 2'- a peptide synthase: ppsA glucopyranose UDP-N-acetyl- -D-muramoyl-L- with (L-alanyl-γ-D-glutamyl- diaminopimelate containing) ASD06_RS14485 MnmA: mnmA epimerase: mce trans-methoxy- phosphate-specific trehalose- acyl-CoA ASD06_RS03635 ASD06_RS15645 metallophosphatase/ deoxyribonucleoside RS00055 D-glucopyranose 1-phosphate alanyl-γ-D-glutamyl-meso-2,6- di-trans,octa-cis-undecaprenyl phosphate meso-2,6-diaminopimeloyl- β (2R)- mono-mycolate phosphatase: -ketoadipyl- [+ 9 isozymes] 5'-monophosphate A H O phosphoenol phosphoglucomutase: diaminopimeloyl-D-alanyl-D-alanine dehydrogenase: 5'-nucleotidase: 2 6-phosphate glucose-1-phosphate D-alanine) tetrapeptide CoA thiolase: a reduced a nucleobase a [SAMP] C- a 2-thiouridine 34 ethylmalonyl-CoA pyruvate ASD06_RS00910 glucose-6- otsB ASD06_RS10880 an acyl-CoA CO H + formaldehyde succinate a leader sequence a peptide ASD06_RS10615 α,α-trehalose adenylyltransferase: ASD06_RS14135 dimethylthiophosphate 4-nitrophenol 2 ferredoxin [iron- within DNA terminal glycine in tRNA phosphate phospho-N-acetylmuramoyl- a mature peptidoglycan phosphopyruvate [+ 2 isozymes] 6-phosphate glgC α,α-trehalose LD-carboxypeptidase: [+ 12 isozymes] sulfur] cluster a ribonucleoside isomerase: pentapeptide- transferase: with D,D cross-links (meso- [DNA] hydratase: eno trehalose- a (1->4)- ASD06_RS14320 succinyl-CoA ASD06_RS06220 ADP-α-D-glucose diaminopimelate containing) (2E)-oct-2-enoyl-CoA Detoxification α-D-glucan ASD06_RS18265 a nascent peptidoglycan a nascent peptidoglycan a mature peptidoglycan RS09935 2-phospho- phosphatase: F6P a nascent peptidoglycan with otsB glycogen phospho-N-acetylmuramoyl- with L,D cross links (meso- with (L-alanyl-γ-D-glutamyl- with (L-alanyl-γ-D-glutamyl- enoyl-CoA D-glycerate (L-alanyl-γ-D-glutamyl-meso- 34 a peptidoglycan guanosine 2251 3''-O-acetyl- pentapeptide- transferase: meso-2,6-diaminopimeloyl- hydratase: reactive oxygen species degradation an N-terminal an L-phenylalanyl- a [protein]-S- a uridine a D-aminoacyl- NaMN carbonic acid glutamine-- synthase: α diaminopimelate containing) meso-2,6-diaminopimeloyl- 3-methylbutanoate dimer (S. aureus) ADP-ribose cys α α UDP- -D-glucose 2,6-diaminopimelate) tripeptide arsenate arginyl-[protein] Phe sulfanyl-L-cysteine in tRNA in 23S rRNA , -trehalose fructose-6- glgA ASD06_RS12505 glycine) tetrapeptide D-alanine) tetrapeptide ASD06_RS14170 [tRNA ] [tRNA] GTP biosynthesis detoxification bifunctional 23S rRNA phosphate a (1->4)- trehalose biosynthesis V (S)-3- superoxide diguanylate cystathionine maltose alpha-D- undecaprenyldiphospho-N-acetylmuramoyl- II (glutaredoxin) D-alanyl-D-alanine metallophosphatase/ (guanosine(2251) O-acetyl-ADP- transaminase α-D-glucan D-glucopyranose hydroxyoctanoyl-CoA tRNA 2- carbonic beta-synthase: 3-phospho- glucosyltransferase: γ a mature peptidoglycan leucyl/phenylalanyl- acetate--CoA ligase: acs D-tyrosyl-tRNA(Tyr) 5'-nucleotidase: -2'-O)- ribose deacetylase: cyclase: RS05145 α-D- (isomerizing) 6-phosphate L-alanyl- -D-glutamyl-meso-2,6- a mature peptidoglycan with superoxide arsenate thiouridine(34) carboxypeptidase/ anhydrase: ASD06_RS03375 D-glycerate treS 1,4-alpha- a glycogen alpha-D-glucose with L,D cross-links (meso- a mature peptidoglycan 3-hydroxyacyl-CoA tRNA--protein acetate--CoA ligase: acsA ASD06_RS15155 methyltransferase ASD06_RS12365 ASD06_RS14940 glucopyranose diaminopimeloyl-D-alanyl-D-alanine γ dismutase, arsenate synthase D-alanyl-D-alanine- deacylase: ASD06_RS03695 phosphoglycerate α : glmS glucan glycogen debranching phosphate-specific diaminopimelate containing) (L-alanyl- -D-glutamyl-meso- with (L-alanyl-γ-D-glutamyl- dehydrogenase: transferase: RlmB: rlmB ADP- -D-glucose α undecaprenyldiphospho- Fatty Acid and Lipid Biosynthesis Ni: sodN reductase ArsC: endopeptidase: dacB ASD06_RS15050 bifunctional 2-O- [+ 13 isozymes] ser kinase: 1-phosphate -maltose D-glucosamine branching 2,6-diaminopimelate) tripeptide ASD06_RS17310 MnmA: mnmA protein GlgX: glgX phosphoglucomutase: meso-2,6-diaminopimeloyl- ASD06_RS11590 metallophosphatase/ 2251 c-di-GMP muramoylpentapeptide beta-N- hydrogen ASD06_RS14835 [+ 2 isozymes] methylguanosine ASD06_RS06260 6-phosphate protein glycogen debranching ASD06_RS00910 glycine) tetrapeptide ADP-D-ribose acetylglucosaminyltransferase: palmitate biosynthesis 3-oxooctanoyl-CoA arsenite 3-methylbutanoyl-CoA diphosphate 5'-nucleotidase: in 23S rRNA acetate CO H O GlgB: glgB peroxide AMP a [protein]- a 2-thiouridine 34 an uncharged 2 2 phosphoglucosamine protein GlgX: glgX [+ 2 isozymes] murG (type II fatty acid synthase) fatty acid elongation -- saturated L-phenylalanyl-L- a D-amino acid ASD06_RS10615 α-D-glucopyranose Phe a peptidoglycan RS17250 13-DPG mutase: a maltodextrin 3-ketoacyl- arginyl-[protein] a tRNA L-cysteine in tRNA tRNA β-D- a glycogen 1-phosphate catalase/ with D,D cross- α-maltose 1- ASD06_RS08165 lipid II (meso diaminopimelate containing) CoA thiolase: D-ala ribosylnicotinate type I malto-oligosyltrehalose an acetoacetyl-[acp] an acetoacetyl-[acp] peroxidase link (S. aureus) phosphate α-D-glucosamine UTP--glucose- ASD06_RS06105 synthase: treY HPI: katG glyceraldehyde- 1-phosphate arsenite alpha-1,4-glucan-- 1-phosphate 3-oxoacyl- H O hydroxyl radical 3-phosphate uridylyltransferase hexanoyl-CoA 2 N-acetyl-D-glucosaminyl-N- an [amino-group carrier 2''-O-acetyl- maltose-1-phosphate bifunctional UDP-N- an N-terminal (S)-5-amino-3- (1S,2R)-1- a siderophore- triose-phosphate dehydrogenase: a maltooligosyl-trehalose GalU: galU [acyl-carrier- an L-phenylalanyl- acetyl-CoA carbamoyl protein]-C-terminal-γ- RS16910 O Phe acetylmuramoyl-L-alanyl-D-glutamyl- ser C-(indol-3- L-ornithine a PII protein ADP-ribose cys a protein maltosyltransferase: acetylglucosamine 2 L-lysyl-[protein] oxohexanoate bound Fe(III) isomerase: gap dTDP-β-L-rhamnose protein] acyl-CoA [tRNA ] phosphate UTP (L-glutamyl)-L-glutamate diphosphorylase/ UDP-α-D-glucose 6-carboxy-L-lysyl-D-alanine yl)glycerol ASD06_RS06255 ASD06_RS00890 malto-oligosyltrehalose reductase: dehydrogenase: cystathionine D-glyceraldehyde biosynthesis 3-phosphate acetylglutamate DHAP a (1->4)- glucosamine-1- trehalohydrolase: treZ fabG a 3-oxoacyl-[acp] ASD06_RS10880 3-keto-5- O-acetyl-ADP- beta-synthase: proteasome 3-phosphate α-D-glucopyranose leucyl/phenylalanyl- ornithine kinase: argB ferric reductase: α-D-glucan phosphate N- [+ 12 isozymes] LD-carboxypeptidase: aminohexanoate [protein-PII] ribose deacetylase: ASD06_RS03375 ATPase: arc α,α-trehalose a (3R)-3- tRNA--protein tryptophan ASD06_RS19025 acetyltransferase 1-phosphate ASD06_RS14320 cleavage protein: carbamoyltransferase: uridylyltransferase: an [amino-group carrier ASD06_RS12365 GDP-mannose biosynthesis 1,4-alpha- glucose-1-phosphate hydroxybutanoyl-[acp] transferase: synthase: an unfolded GlmU: glmU 3-oxoacyl- (2E)-hexenoyl-CoA argF ASD06_RS00355 protein]-C-terminal- lanthionine RS05640 glucan thymidylyltransferase ASD06_RS15115 ASD06_RS06445 protein fructose- α ASD06_RS11590 γ-(5-phospho-L- D-glucopyranose branching N-acetyl- -D- [acyl-carrier- RfbA: rfbA enoyl-CoA N-acetyl-D-glucosaminyl-N- trpB acetate ADP-D-ribose Fe 2+ a siderophore bisphosphate glucosamine dTDP-α-D-glucose beta- protein] glutamyl)-L-glutamate 6-phosphate protein hydratase: acetylmuramoyl-L-alanyl-D- a uridylylated aldolase: glucose-6- 1-phosphate ketoacyl- reductase: L-phenylalanyl- D-ala acetoacetate (S)-3- L-citrulline GlgB: glgB ASD06_RS14170 a tRNA Phe D-glyceraldehyde phosphate dTDP-glucose 4,6- trehalose biosynthesis I L-lysyl-[protein] glutamyl-6-carboxy-L-lysine aminobutanoyl-CoA PII protein ASD06_RS17155 bifunctional UDP-N- a (2E)-but-2-enoyl-[acp] ACP fabG 3-phosphate trp isomerase: a GlgE-glycogen dehydratase: rfbB (S)-3- class II fructose- acetylglucosamine D-glucopyranose synthase a (3R)-3- RS04450 ASD06_RS06220 dTDP-4-dehydro-6- α hydroxyhexanoyl-CoA bisphosphate diphosphorylase/ UDP- -D-glucose 6-phosphate enoyl-ACP a 2,3,4-saturatedII: fabF deoxy-α-D-glucopyranose hydroxyacyl-[acyl- 3-hydroxyacyl-CoA aldolase: fbaA F6P glucosamine-1- reductase fatty acyl-[acp] Nucleoside and Nucleotide Degradation carrier protein] dehydrogenase: 5-methoxy-6- a Chi-site containing a RecA DNA a peptide with a [lipoyl-carrier phosphate N- FabI: fabI NaMN isobutanoate H O a D-tyrosyl- 6 L(or D)-O- mannose-6- trehalose-6- double stranded recombination diphosphate 2 an N-terminal ethylphosphate protein]-N -[(R) ASD06_RS17310 methylbenzimidazole Tyr GTP a protein acetyltransferase enoyl-ACP purine nucleotides degradation II (aerobic) [tRNA ] phosphoserine phosphate dTDP-4-dehydro- phosphate DNA with a blunt end and repair protein Xaa-L-proline alkaline -dihydrolipoyl]- PRPP biosynthesis GlmU: glmU superpathway of pyrimidine phosphoserine β-D-fructose 1,6- isomerase: β synthase: reductase: 3-oxohexanoyl-CoA adenylate/guanylate L-lysine CrcB -L-rhamnose deoxyribonucleosides degradation nicotinate-nucleotide-- phosphatase: phoA dihydrolipoyl phosphatase proteasome: bisphosphate ASD06_RS17400 D-ribose 5- UDP-N-acetyl- ASD06_RS14895 ASD06_RS08065 acetate--CoA ligase: acs inorganic cyclase domain- dTDP-4- dimethylbenzimidazole leucyl D-tyrosyl-tRNA(Tyr) bifunctional RNase dehydrogenase: prcA prcB α-D-glucosamine UDP-α-D- acetyl-CoA C- AMP 2'-deoxycytidine exodeoxyribonuclease acetate--CoA ligase: acsA diphosphatase: containing protein: SerB: serB class II fructose- D-mannopyranose phosphate dehydrorhamnose aminopeptidase: deacylase: H/acid phosphatase: lpdA ribose-phosphate α,α-trehalose a butanoyl-[acp] acetyltransferase: phosphoribosyltransferase: V: recD recC ASD06_RS02820 a [lipoyl-carrier bisphosphatase: 6-phosphate galactose enoyl-ACP ASD06_RS09650 ASD06_RS11745 ASD06_RS15050 ASD06_RS04780 serine a peptide pyrophosphokinase: reductase: rfbD ASD06_RS00985 cobT protein]-N 6 -[(R glpX 6-phosphate biosynthesis reductase: bifunctional nucleoside [+ 2 isozymes] cyclic-GMP phosphomannomutase/ ASD06_RS15995 a trans-2- ethanol + + dTDP-β-L-rhamnose beta-ketoacyl- [+ 3 isozymes] )-lipoyl]-L-lysine Na RS15340 Na phosphoglucomutase: trehalose- UDP-α-D-glucose a 2,3,4-saturated ASD06_RS08065 metallophosphatase/ deaminase: a double stranded DNA isobutanoyl-CoA diphosphate ribose-phosphate trehalose ACP synthase enoyl-[acyl- 5-methoxy-6- a peptide with F6P phosphatase: fatty acyl-[acp] 5'-nucleotidase: ASD06_RS15720 AMP a proteinogenic Tyr ASD06_RS02505 UDP-glucose enoyl-ACP carrier protein] butanoyl-CoA thymidine nicotinate with a RecA protein an N-terminal D-tyrosine a tRNA diphosphokinase: biosynthesis IV II: fabF methylbenzimidazole + α-D-mannose otsB 4-epimerase ASD06_RS10615 cytidine loaded 3' overhang phosphate H amino acid glucose-6- ASD06_RS14640 reductase thymidine ribotide phosphate L-proline GalE: galE acyl-CoA bifunctional deaminase: phosphate 1-phosphate α-maltose α,α-trehalose a 3-oxohexanoyl-[acp] FabI: fabI phosphorylase: PRPP UDP-α-D-galactose dehydrogenase: IMP ASD06_RS03090 TatC isomerase: maltose alpha-D- metallophosphatase/ ASD06_RS10880 ASD06_RS03085 ASD06_RS06220 glucosyltransferase: 3-oxoacyl- 5'-nucleotidase: RNase III mRNA an all-trans- an [RNA]-3'- 4-(2'- enoyl-ACP GMP NaMN lysine within a D-tryptophanyl- (S)-2- an L-aspartyl- histidinol treS [acyl-carrier- [+ 12 isozymes] ASD06_RS15155 2'-deoxyuridine thymine 5-methoxybenzimidazole an octanoyl-[acp] processing 1,4-dihydroxy- polyisoprenyl glu ribonucleoside- carboxyphenyl)- repressor LexA D-glucopyranose GDP-α-D- IMP dehydrogenase: gcv protein H [tRNA Trp ] [tRNA Asn ] α α reductase: 2-naphthoate aminobutanoate 6-phosphate , -trehalose protein] guaB substrate diphosphate 2',3'- Asp-tRNA(Asn) 4-oxobutyryl-CoA histidinol mannose ASD06_RS08065 crotonyl-CoA bifunctional 1,4-dihydroxy- transcriptional reductase: adenosine cyclophosphate /Glu-tRNA(Gln) dehydrogenase: enoyl-ACP metallophosphatase/ nicotinate-nucleotide-- lipoyl(octanoyl) RNA 2',3'-cyclic 2-naphthoyl- repressor fabG enoyl-CoA 1,4-dihydroxy- D-tyrosyl-tRNA(Tyr) glutamate-- amidotransferase: hisD CrgA reductase 5'-nucleotidase: dimethylbenzimidazole transferase ribonuclease III: phosphodiesterase: CoA synthase: LexA: lexA hydratase: adenosine deaminase: XMP 2-naphthoate deacylase: cysteine ligase: gatB gatA gatC a (3R)-3- FabI: fabI ASD06_RS10615 phosphoribosyltransferase: LipB: lipB ASD06_RS00410 an [RNA]-3'-thpR ASD06_RS09010 ASD06_RS14170 ASD06_RS08565 polyprenyltransferase: ASD06_RS15050 ASD06_RS05440 an L-asparaginyl- 1,4-dihydroxy-2- cleaved his nickel cofactor Cofactor, Carrier, and Vitamin Biosynthesis hydroxyhexanoyl-[acp] cobT Asn [2Fe-2S] iron-sulfur thioredoxin adenosine deaminase: bifunctional bifunctional ASD06_RS09045 ribunucleoside- [tRNA ] naphthoyl-CoA repressor LexA superpathway of tetrahydrofolate biosynthesis superpathway of coenzyme A biosynthesis I (bacteria) flavin biosynthesis I (bacteria and plants) mycothiol biosynthesis adenosylcobalamin biosynthesis (S)-3- a [glycine-cleavage biosynthesis cluster biosynthesis pathway metallophosphatase/ metallophosphatase/ uracil 2-deoxy-α-D- RNase III 2'-phosphate from adenosylcobinamide-GDP I hydroxybutanoyl-CoA ASD06_RS03070 γ 5'-nucleotidase: 5'-nucleotidase: ribose 1-phosphate acyl-carrier protein complex H protein] an mRNA fragment -L-glutamyl-(S)- nicotinate adenine 3-methyl-2- a 5,10- D-glucopyranose 5-methoxybenzimidazole processing Trp 3-hydroxyacyl-CoA nicotinate 6 D-tryptophan a tRNA 2-aminobutanoate an oxidized CDP-diacylglycerol CDP-diacylglycerol ASD06_RS15155 ASD06_RS10615 N -octanoyl-L-lysine product mRNA RS01765 dinucleotide L-cysteine desulfurase GTP oxobutanoate methylenetetrahydrofolate GTP 6-phosphate 5,6-dimethylbenzimidazole dehydrogenase: inosine ribotide phosphate DMKH thioredoxin biosynthesis III biosynthesis I 2 nicotinate-nucleotide-- a (2E)-hex-2-enoyl-[acp] bifunctional inositol-3- ASD06_RS17310 guanosine pyridin-1-ium- cysteine 3-methyl-2-oxobutanoate dimethylbenzimidazole purine-nucleoside metallophosphatase/ GTP GTP cyclohydrolase phosphate thiazole component of thiamine diphosphate biosynthesis II an acyl-[acyl- DHAP 2-deoxy-D-ribose 3,5-dicarboxylate hydroxymethyltransferase: phosphoribosyltransferase: enoyl-ACP acetoacetyl-CoA phosphorylase: 5'-nucleotidase: a [protein] N- 527 desulfurase: cyclohydrolase synthase: DHAP carrier protein] 5-phosphate a single a [DNA]-3'- a guanine an L-glutamyl- pyridoxamine mononucleotide panB II: ribA thioredoxin- purine-nucleoside 5-hydroxybenzimidazole NaMN methanethiol O-succinyl-L- terminal-formyl- roseoflavin ASD06_RS00795 ASD06_RS17030 cobT reductase ASD06_RS02970 ASD06_RS15155 stranded DNA hydroxyl a type IV prepilin in 16S rRNA Gln a protein I FolE: folE GTP cyclohydrolase α-ribazole disulfide acetyl-CoA C- phosphorylase: homoserine [tRNA ] bifunctional 5'-phosphate RS09570 ATP- cys FabI: fabI L-methionine 16S rRNA Asp-tRNA(Asn) an S-sulfanyl-[L- GTP asp II: ribA 5'-phosphate reductase: sn-glycerol acetyltransferase: ASD06_RS02970 deoxyribose- pyridoxamine dependent Ins(3)P UDP-N-acetyl- enoyl-ACP hypoxanthine xanthosine (guanine(527)-N(7) /Glu-tRNA(Gln) riboflavin kinase/ bacillolysin: cysteine desulfurase] cyclohydrolase 2-dehydropantoate trxB 3-phosphate ASD06_RS03360 phosphate nicotinate-nucleotide-- exodeoxyribonuclease exodeoxyribonuclease 5'-phosphate sacrificial 2,5-diamino-6-(5-phospho-D- α-D-glucosamine SufS family adenosylcobinamide- reductase: cystathionine peptide )-methyltransferase amidotransferase: FAD synthetase: ASD06_RS12150 I FolE: folE aspartate 1- aldolase: dimethylbenzimidazole VII: ASD06_RS03750 III: xth prepilin peptidase: oxidase: pdxH sulfur 2-dehydropantoate ribosylamino)pyrimidin-4(3H)-one GDP sn-glycerol glycerol-3- [+ 2 isozymes] guanine gamma-synthase: RsmG: rsmG ASD06_RS12980 7,8- cysteine a [ThiS sulfur- ASD06_RS08065 an acyl phosphate deoC deformylase: an N 7 - gatB gatA gatC transferase decarboxylase: D-inositol-3-phosphate 3-phosphate phosphate phosphoribosyltransferase: ASD06_RS03765 ASD06_RS03455 exodeoxyribonuclease ASD06_RS06845 roseoflavin 2-reductase: bifunctional ribazoletransferase: 527 an L-glutaminyl- PLP dihydroneopterin ASD06_RS05140 desulfurase: carrier protein] acetyl-CoA hypoxanthine purine-nucleoside def methylguanine a peptide LarE: larE glycosyltransferase: a reduced acyltransferase: cobT III: xth [tRNA Gln ] 5'-phosphate an S-sulfanyl-[cysteine ASD06_RS16010 diaminohydroxyphosphoribosylaminopyrimidine sufS ASD06_RS11720 a hexanoyl-[acp] hydroxylase: phosphorylase: D-glyceraldehyde in 16S rRNA RS13185 5-carboxy-1-(5- 3'-triphosphate mshA thioredoxin ASD06_RS04175 acetaldehyde desulfurase]-[disordered- β deaminase/5-amino-6-(5-phosphoribosylamino) cysteine adenosylcobalamin acyl-phosphate ASD06_RS06565 ASD06_RS02970 3-phosphate a ribonucleoside a single-stranded O-phospho-β- -alanine (R)-pantoate a 1-acyl-sn met succinate a 2'- a cleaved type an N-terminal L- form scaffold uracil reductase RibD: ribD desulfurase: 5'-phosphate beta-ketoacyl- glycerol 3- 5-hydroxybenzimidazole 5'-monophosphate oligodeoxyribonucleotide a [DNA]-3'- a peptide formate D-ribofuranosyl) 1-O-(2-acetamido- -glycerol 3- bifunctional nicotinate deoxyribonucleoside IV prepilin methionyl-[protein] protein] complex 5-amino-6-(5-phospho- a carboxy- ACP synthase phosphate ribotide phosphate hydroxyl pyridin-1-ium-3- 2-deoxy-α-D- ASD06_RS00795 phosphate acetaldehyde- 7,8- an [L-cysteine II: fabF acyltransferase: xanthine 5'-monophosphate pantoate--beta- D-ribosylamino)uracil adenylated- D-glyceraldehyde 1-acyl-sn-glycerol- carbonyl adenylate dihydroneopterin glucopyranosyl)-1D-myo ASD06_RS18185 CoA/alcohol ATP- chorismate alanine ligase: bifunctional desulfurase]-S- [ThiS sulfur- factor 420 xanthine:NAD+ 3'-phosphate -inositol 3-phosphate 3-phosphate a 3-oxooctanoyl-[acp] 3-phosphate pseudouridine dehydrogenase: RS11930 dependent ASD06_RS09520 sulfanyl-L-cysteine carrier protein] a 2,3,4-saturated all-trans- D-glycero-D- a guanine 966 a uracil 1498 a supercoiled 6-O-cis-methoxy- a [cysteine desulfurase]- diaminohydroxyphosphoribosylaminopyrimidine adenosylcobalamin polyglutamylation acyltransferase: degradation oxidoreductase: adhE ARP an apo-[aryl- a ribonucleoside a single aminodeoxychorismate/ 1-deoxy-D- a 1-acyl-sn tyr SAM coenzyme A 1,2-diacyl-sn- dodecaprenyl 1,4-dihydroxy- manno-heptose mycolyl-trehalose a DNA segment sacrificial S-sulfanyl-[disordered- deaminase/5-amino-6-(5-phosphoribosylamino) gly ASD06_RS15740 ASD06_RS06565 triphosphate in 16S rRNA in 16S rRNA duplex DNA anthranilate synthase D-ribulose 5-phosphate cysteine xylulose-5- oxidized 3-oxoacyl- -glycerol 3- carrier protein] CTP diphosphate 2-naphthoate stranded DNA 7-phosphate 16S rRNA replicative 6-phosphate sulfur uracil reductase RibD: ribD [+ 5 isozymes] pseudouridine acetyl-CoA glycerol 3-phosphate bifunctional heptose 16S rRNA form scaffold component II: (R)-pantothenate 1-(2-acetamido- desulfurase: phosphate factor 420-0 [acyl-carrier- phosphate urate trehalose- recombinase transferase D-erythro-7,8- glycine coenzyme a 1,2-diacyl- (guanine(966)-N(2) (uracil(1498)-N(3))- DNA helicase: protein] complex ASD06_RS16630 3,4-dihydroxy- 5-amino-6-(5-phospho- α synthase: protein] 1-acyl-sn-glycerol- 7-phosphate phosphatase: LarE: larE cysteine 2-deoxy- -D- ASD06_RS00795 sn-glycerol )-methyltransferase methyltransferase: ASD06_RS17075 RecA: recA a [LarE]-S-[5-carboxy- dihydroneopterin type I pantothenate 2-butanone- D-ribitylamino)uracil oxidase F420-0:L- 3-phosphate bifunctional FO holo-ACP synthase: phosphatidate 1,4-dihydroxy- DNA primase: kinase/heptose aminodeoxychorismate/ glucopyranosyl)- dxs reductase: RsmD: rsmD ASD06_RS04270 [+ 5 isozymes] otsB a DNA segment 1-(5-O-phosphono- desulfurase: kinase: ThiO: thiO glutamate 3-phosphate pseudouridine biosynthesis protein ASD06_RS08140 cytidylyltransferase: 2-naphthoate 1-phosphate 2 an N 3 - trehalose- FliP dihydroneopterin 4-phosphate 1D-myo-inositol a thiocarboxylated- 1-deoxy-D- fabG acyltransferase: ASD06_RS00225 an N - a single β ASD06_RS00795 anthranilate synthase phosphatidate 966 1498 in reverse -D-ribofuranosyl) aldolase: folB ASD06_RS08150 synthase: ribA ligase: cofE ASD06_RS15740 5'-phosphate CofGH: ASD06_RS01875 ASD06_RS13280 polyprenyltransferase: adenyltransferase: methylguanine methyluracil cis-methoxy- an S-sulfanyl-[cysteine component II: N-acetyl-1-D-myo- [ThiS sulfur- 2-iminoacetate xylulose 5- oxidized a (3R)-3- superpathway of purine deoxyribonucleosides degradation stranded DNA orientation pyridin-1-ium-3- (R)-4'- cytidylyltransferase: ASD06_RS09045 D-glycero-β-D-ASD06_RS13810 in 16S rRNA in 16S rRNA mono-mycolate desulfurase]-S- 6-(hydroxymethyl) ASD06_RS12040 1-deoxy-L-glycero- inositol-2-amino- carrier protein] phosphate factor 420-1 hydroxyoctanoyl-[acp] [+ 5 isozymes] pseudouridine- carbonyl]-L-cysteine phosphopantothenate a 1,2-diacyl- ASD06_RS13280 3',5'-ADP a holo-[aryl- ssDNA/pppN(pN) sulfanyl-[disordered- ARP adenosylcobalamin 2-deoxy-alpha- D- 5'-phosphate 5-amino-5-(4-hydroxybenzyl)-6- a CDP-2,3,4-saturated- manno-heptose ATP- -7,8-dihydropterin 4-amino-4- tetrulose 4-phosphate a CDP- 5'-deoxyadenosine 2-iminoacetate carrier protein] hybrid bifunctional salvage from cobalamin thiazole synthase: sn-glycerol (D-ribitylimino)-5,6-dihydrouracil met diacylglycerol n -1 1,7-bisphosphate dependent form scaffold 2-amino-4-hydroxy-6- deoxychorismate glucopyranoside glycosidase: 2'-deoxyguanosine DMK-12 phosphopantothenoylcysteine ASD06_RS04045 3-phosphate diacylglycerol RS00090 sacrificial protein] complex hydroxymethyldihydropteridine 6,7-dimethyl-8- deacetylase: mshB ASD06_RS14255 aminodeoxychorismate decarboxylase/ cob(I)alamin oxidized phosphatidate 2'-deoxyadenosine sulfur diphosphokinase: folK ribityllumazine N-acetyl-1-D-myo- lipoate biosynthesis uracil lyase: ASD06_RS07120 phosphopantothenate-- 2-[(2R,5Z)- factor 420-2 cytidylyltransferase: (7,8-dihydropterin- and incorporation I a (2E)-oct-2-enoyl-[acp] transferase synthase: inositol-2-amino- 2-carboxy-4- ASD06_RS13280 purine-nucleoside UDP-N-acetyl- decaprenyl-diphospho-N- 3-aci- all-trans- a dipetide with an N- 6-O-trans-keto- a supercoiled cysteine ligase CoaBC: coaBC α coenzyme A AsbD acyl- hydroxypyruvate N-formimino- DNA with lesion propionamide LarE: larE a [cysteine 6-yl)methyl 4-aminobenzoate ASD06_RS06640 2-deoxy-alpha- D- methylthiazol-5(2H pyridoxal 5'-phosphate biosynthesis I phosphorylase: -D-glucosamine acetylmuramoyl-pentapeptide nitropropanoate tridecaprenyl 1,4-dihydroxy- terminal L-aspartate mycolyl-trehalose duplex DNA pyridin-1-ium-3- (R)-4'- cob(II)alamin enoyl-ACP a CDP- adenosine carrier protein L-glutamate desulfurase]-(S- diphosphate glucopyranoside an octanoyl-[acp] )-ylidene]ethyl biotin-carboxyl carrier ASD06_RS02970 diphosphate 2-naphthoate excinuclease amidase: 6-phosphate DNA carboxylate-5- phosphopantothenoyl- reductase diacylglycerol deaminase: formimidoylglutamate trehalose- RS06390 sulfanyl) -[disordered- deacetylase: mshB lipoyl(octanoyl) phosphate D-erythrose protein assembly purine-nucleoside undecaprenyldiphospho- ABC subunit UvrA: ASD06_RS15305 helicase thiocarboxylate 2 dihydropteroate L-cysteine 6,7-dimethyl-8-(1-D-ribityl)lumazine cob(I)yrinic acid demethylmenaquinol- FabI: fabI ASD06_RS08565 nitronate pyruvate deiminase: phosphatase: form scaffold transferase 4-phosphate phosphorylase: muramoylpentapeptide beta-N- 1,4-dihydroxy- peptidase E: ASD06_RS09210 amidase: PcrA: pcrA mononucleotide bifunctional a,c-diamide adenosine holo-ACP synthase: monooxygenase: dehydrogenase: otsB protein] complex synthase: folP GlcN-Ins 9 biosynthesis enoyl-ACP a [biotin carboxyl- ASD06_RS02970 acetylglucosaminyltransferase: ASD06_RS11785 ASD06_RS17630 [+ 2 isozymes] ASD06_RS00630 [+ 3 isozymes] ATP- phosphopantothenoylcysteine riboflavin synthase: adenosyltransferase: a [lipoyl-carrier protein]LipB: lipB ASD06_RS08140 ASD06_RS07805 2-naphthoate ASD06_RS10575 trehalose- dihydropteroate all-trans- reductase: carrier protein]-L-lysine deaminase: murG N-formyl- DNA without a single dependent ASD06_RS06655 ASD06_RS01115 6 UTP and CTP dephosphorylation I polyprenyltransferase: propanoate trans-keto- decarboxylase/ cysteine--1-D-myo- N -octanoyl-L-lysine 2-(2-carboxy-4- 1,4-dihydroxy- biotin--[acetyl-CoA- purine-nucleoside ASD06_RS03070 lesion stranded DNA sacrificial synthase: folP nonaprenyl ASD06_RS08065 ASD06_RS09045 L-glutamate mono-mycolate phosphopantothenate-- cob(II)alamin- inosityl 2-amino- methylthiazol-5- 4-phospho- 2-naphthoate carboxylase] ligase: phosphorylase: [unspecified sulfur lipoyl diphosphate UTP a holo-[AsbD acyl- a proteinogenic RS14920 a [cysteine desulfurase]- cysteine ligase CoaBC: coaBC riboflavin [corrinoid 2-deoxy-alpha-D- yl)ethyl phosphate D-erythronate 2-deoxy-α-D- decaprenyl-pyrophosphoryl- UDP 3',5'-ADP 3-oxopropanoate nitrite degradation CO glycolyl-CoA NADH asp 7,8- synthase: lipA an octanoyl-[acp] ASD06_RS02830 ASD06_RS02970 carrier protein] 2 amino acid transferase adenosyltranferase] (N-acetylglucosamine)-N- [scaffold protein- dihydropteroate glucopyranoside a [lipoyl-carrier 1,4-dihydroxy- a [biotin carboxyl- ribose 1-phosphate 2'-deoxyinosine products] LarE: larE 4'-phosphopantetheine bifunctional CTP synthase: DMKH2-13 (2Fe-2S)] complex ligase: 6 2-naphthoate beta-ketoacyl- carrier protein]-N acetylmuramyl-(pentapeptide) 1-(5-O-phospho-β- bifunctional riboflavin kinase/ protein]-N -[(R)- ASD06_RS07505 D-ribofuranosyl)-5- ASD06_RS05815 dihydrolipoyl]-L-lysine polyprenyltransferase: ACP synthase 6 -biotinyl-L-lysine folylpolyglutamate pantetheine- FAD synthetase: (3R)-3-hydroxy-2-oxo- UDP (sulfanylcarbonyl) phosphate ASD06_RS12980 cob(I)alamin- ASD06_RS09045 II: fabF synthase/ D-glyceraldehyde 4 phosphooxybutanoate 2-deoxy-D-ribose CTP 10 37 β deacetylmycothiol pyruvate an N - + guanine a monocarboxylic -D-glucose pyridin-1-ium-3- adenylyltransferase: [corrinoid an L-methionyl- coenzyme A [EntB aryl- coenzyme A 1,4-dihydroxy- pyruvate malonyl-CoA H a uridine in tRNA CAIR RS13065 a [co-chaperone]- dihydrofolate 3-phosphate phosphoserine 5-phosphate VibB GGPP Phe FMN adenosyltranferase] a 3-oxodecanoyl-[acp] [initiator tRNA Met ] formyltetrahydrofolate in tRNA acid amide 6-phosphate carbonyl adenylate [scaffold protein- synthase: coaD mycothiol a [biotin carboxyl- carrier protein] 2-naphthoate tRNA amidase: ATP- cob(I)yrinic acid transaminase: demethylmenaquinol-9 tRNA inositol-3- 5-(carboxyamino) (2Fe-2S)] complex synthase: carrier-protein dimer]- UMP dependent ASD06_RS03970 3'-dephospho- bifunctional 1-deoxy-D- ASD06_RS13980 3-oxoacyl- deoxyribose- (guanosine(37)-N1) ASD06_RS15305 dihydrouridine phosphate imidazole a,c-diamide 6 CDP pyruvate type III polyketide CoA mshD xylulose-5- N -biotinyl-L-lysine 1,4-dihydroxy- -methyltransferase synthase synthase: sacrificial 7,8-dihydrofolate riboflavin kinase/ adenosyltransferase: 4-phosphooxy- [acyl-carrier- phosphate bifunctional methionyl-tRNA holo-ACP synthase: holo-ACP synthase: amidase: ribonucleotide acetyl-CoA dehydrogenase: synthase: monoglutamate dephospho- phosphate aldolase: deoC 2-naphthoate 1 TrmD: trmD ASD06_RS00630 DusB: dusB ASD06_RS17030 mutase: purE sulfur FAD synthetase: ASD06_RS01115 mycothiol L-threonine protein] acetyl-CoA metallophosphatase/ formyltransferase: ASD06_RS08140 ASD06_RS08140 ASD06_RS10575 ASD06_RS02940 an N - CoA kinase: synthase: carboxylase polyprenyltransferase: a 5,6-dihydrouridine RS18030 transferase a [chaperone-ATP]- ASD06_RS12980 adenosylcob(III) reductase: carboxyl 5'-nucleotidase: ASD06_RS06705 methylguanine 37 a monocarboxylate Ins(3)P AIR ASD06_RS06325 dxs biotin carboxylase ASD06_RS09045 in tRNA LarE: larE [co-chaperone]- alamin-[corrinoid fabG D-glyceraldehyde 3-phosphate CMP ASD06_RS10615 in tRNA Phe a [LarE]-S-[1-(5-O FAD transferase: acetaldehyde [scaffold protein- adenosyltranferase] folate transformations III (E. coli) subunit: a holo-[EntB aryl- a holo-[VibB aryl- -phosphono-β-D- NAD de novo biosynthesis a (3R)-3- ASD06_RS06525 bifunctional an N-formyl- 3',5'-ADP 3',5'-ADP acetyl-CoA CO NADH octoketide coenzyme A 1-deoxy-D- 3-amino-1- ASD06_RS08750 bifunctional carrier protein] carrier protein] 2 (2Fe-2S)] complex a 7,8-dihydrofolate I (from aspartate) cob(I)yrinic acid bifunctional L-methionyl- a tetrahydrofolate ribofuranosyl)-5- xylulose 5- hydroxyacetone hydroxydecanoyl-[acp] a [carboxyl-carrier metallophosphatase/ metallophosphatase/ demethylmenaquinol-4 a,c-diamide acetaldehyde- [initiator tRNA met ] (sulfanylcarbonyl) a tetrahydrofolate 1-phosphate 6 5'-nucleotidase: 5'-nucleotidase: dihydrofolate thiamine diphosphate salvage II phosphate protein dimer]-N - CoA/alcohol pyridin-1-ium-3- asp adenosyltransferase: ASD06_RS15155 RS07935 reductase: carboxybiotinyl-L-lysine dehydrogenase: ASD06_RS10615 carbonyl]-L-cysteine L-aspartate ASD06_RS01115 a [glycine-cleavage α 37 (2Z,4E)-2- a [chaperone- ASD06_RS14855 4-amino-2-methyl-5- methionine adhE bifunctional uridine an -D- a [protein]- a guanine (indol-3-yl) a [protein]- α-D-glucosamine ATP- an [2Fe-2S] oxidase: complex H protein] coenzyme A [EntF L-seryl- FAD FMN NAD(P)H H + canavaninosuccinate hydroxyhexa- ADP]-[disordered- dihydrofolate pyrimidinemethanol adenosylcobalamin synthase: metH metallophosphatase/ a sulfurated [sulfur carrier] SAM galactoside L-threonine in tRNA acetamide L-histidine 6-phosphate dependent cluster protein ASD06_RS09515 a (2E)-dec-2-enoyl-[acp] 6 carrier protein] form scaffold dihydrofolate pyridoxine bis(guanylyl molybdopterin) acetyl-CoA 5'-nucleotidase: N -octanoyl-L-lysine tRNA amidase: 2,4-dienedioate glucosamine- sacrificial reductase: 2-iminosuccinate bifunctional methionine synthase: 4-oxalocrotonate protein] complex reductase: 5'-phosphate cofactor sulfurylation purine ribonucleosides degradation ASD06_RS15155 alpha- (guanosine(37)-N1) ASD06_RS15305 histidine kinase: 6-phosphate sulfur ASD06_RS12900 hydroxymethylpyrimidine ASD06_RS00775 enoyl-ACP FAD:protein FMN tautomerase: quinolinate ASD06_RS14855 galactosidase: flavin reductase: argininosuccinate -methyltransferase amidase: ASD06_RS08685 deaminase: RS00600 kinase/ pyridoxamine reductase fatty acid biosynthesis cytidine 5'-deoxyadenosine lipoyl holo-ACP synthase: transferase: ASD06_RS17095 transferase a tetrahydrofolate cys ASD06_RS09980 lyase: argH TrmD: trmD ASD06_RS00630 a [protein]- nagB synthase phosphomethylpyrimidine dihydrofolate 5'-phosphate initiation (type II) ASD06_RS08140 ASD06_RS03190 an N 1 - LarE: larE NAD salvage serine FabI: fabI degradation I synthase: lipA ASD06_RS17945 (3E)-2-oxohex- NadA: nadA adenosine 37 N-phospho- F6P pyridin-1-ium-3,5- an [Fe-S cluster kinase: thiD reductase: glycine cleavage oxidase: pdxH methylguanine (indol-3-yl)acetate 3-enedioate pathway III (to hydroxymethyltransferase: enoyl-ACP L-histidine bisthiocarboxylate ASD06_RS12900 system protein SufS family acetyl-CoA 5'-deoxyadenosine α-D- a non in tRNA biosynthesis quinolinate nicotinamide riboside) a 7,8-dihydrofolate ASD06_RS16480 a 5-methyltetrahydrofolate reductase: a holo-[EntF HMP-P PLP cysteine acetyl-CoA carboxyl adenosine deaminase: a [glycine-cleavage a [protein]-FMN- FMNH NAD(P) + L-canavanine fumarate mononucleotide GcvH: gcvH 3',5'-ADP galactopyranose galactosylated 2 chaperone]-ATP ASD06_RS08065 6 an unsulfurated L-seryl-carrier + serine desulfurase: transferase: ASD06_RS08565 5'-deoxyadenosine complex H protein] N AMP L-threonine carboxylating NADP [+ 4 isozymes] S-methyl-5'- met protein] galactose acceptor FlhA bifunctional 5-(2-hydroxyethyl) hydroxymethyltransferase: sufS a decanoyl-[acyl- ASD06_RS06525 adenosine deaminase: -[(R)-lipoyl]-L-lysine [sulfur carrier] nicotinate- thymidylate thioadenosine hydroxymethylpyrimidine -4-methylthiazole ASD06_RS01195 carrier protein] malonyl-CoA synthase: cysteine ASD06_RS03070 phosphorylase: pyridin-1-ium- nucleotide kinase/ + ASD06_RS12895 desulfurase: beta-ketoacyl- ASD06_RS14310 3-thioamide-5- molybdopterin biosynthesis diphosphorylase: phosphomethylpyrimidine NAD a (6S)-5-formyltetrahydrofolate [acyl-carrier-protein] S ASD06_RS00795 xanthosine adenosine inosine guanosine a [pyruvate dehydrogenase E2 a [mycoredoxin]- mycothiol- a [protein]-α- a double nadC ACP synthase -malonyltransferase: 5-deoxy-α-D- 2-oxoglutarate phytanoyl-CoA succinate NADP + FMNH 3'-ketolactose Ins(2)P pyrazinamide thiocarboxylate kinase: thiD an [L-cysteine a sulfurated [sulfur carrier] SAM 6 2 stranded DNA ser 4-methyl-5-(2- NAD(+) 5-formyltetrahydrofolate II: fabF protein] N -octanoyl-L-lysine L-cysteine arsenate conjugate L-glutamate mononucleotide desulfurase]-S- ASD06_RS04840 ribose 1-phosphate protein-glutamate O- topoisomerase II: amidase: RS09305 cys NaMN HMP-PP phosphooxyethyl) diphosphatase: methylenetetrahydrofolate methylenetetrahydrofolatecyclo-ligase: inositol threonine/serine Ni pincer complex sulfanyl-L-cysteine methyltransferase ASD06_RS16345 ASD06_RS15305 thiazole nudC reductase [NAD(P)H]: metF dehydrogenase:ASD06_RS14395 bis(guanylyl a 3-oxododecanoyl-[acp] purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside phytanoyl-CoA ADP-forming beta-glucosidase: monophosphatase: ATP nicotinate-nucleotide cysteine a malonyl-[acp] mycoredoxin: flavin reductase: CheR: DNA: amidase: dehydratase: SufS family ASD06_RS07640 molybdopterin) phosphorylase: phosphorylase: phosphorylase: phosphorylase: dioxygenase: succinate--CoA ASD06_RS09435 ASD06_RS07410 ASD06_RS15800 adenylyltransferase: thiamine NMN a 5,10-methylenetetrahydrofolate a 5,10-methenyltetrahydrofolate desulfurase: lipoyl synthase: lipA ASD06_RS02150 ASD06_RS09980 a [protein]-L-ASD06_RS12250 gyrA gyrB ASD06_RS00630 molybdopterin- cysteine GTP cofactor 3-oxoacyl- ASD06_RS02970 ASD06_RS02970 ASD06_RS02970 ASD06_RS02970 ASD06_RS02000 ligase: sucD sucC a negatively pyrazine-2- ASD06_RS00795 ketoacyl-ACP synthase 5-deoxy-D-ribulose 5 myo-inositol pyruvate desulfurase: ASD06_RS04110 phosphate [acyl-carrier- glutamate-O synthase bifunctional bifunctional a [bis(guanylyl III: ASD06_RS04845 1-phosphate β supercoiled DNA carboxylate sufS nicotinate adenine synthase: protein] a [mycoredoxin] 3-keto- -D- -methyl-ester RS00865 adenylyltransferase GTP 3',8- metallophosphatase/ methylenetetrahydrofolate molybdopterin) α-D-ribose-1-phosphate 2-hydroxyphytanoyl- + D-glucopyranose dinucleotide ASD06_RS04060 reductase: a [pyruvate dehydrogenase arsenite mycothiolyl-S-S- succinate succinyl-CoA FMN NADPH H galactose MoeB: moeB cysteine cyclase 5'-nucleotidase: cofactor [bis-MGD cofactor 5'-deoxyadenosine CoA phosphate dehydrogenase/ an acetoacetyl-[acp] met 6 an unsulfurated [sulfur carrier] L-cysteine disulfide ADP a carboxy- desulfurase: NAD+ synthase: NAD+ synthase: ASD06_RS15155 fabG E2 protein] N -lipoyl-L-lysine MoaA: adeninyl adenosylcobamide 2-methyladeninyl methenyltetrahydrofolate chaperone]-S- chaperone]- S-methyl-5'- pyrimidine deoxyribonucleotides adenylated ASD06_RS00795 ASD06_RS12140 ASD06_RS12140 thiamine moaA bifunctional biosynthesis from adenosylcobamide biosynthesis cyclohydrolase: sulfanyl-L-cysteine bis-MGD a (3R)-3- thioadenosine dephosphorylation [small subunit of an [L-cysteine (8S)-3',8-cyclo-7,8- phosphate hydroxydodecanoyl-[acp] acetaldehyde DHAP + metallophosphatase/ adenosylcobinamide-GDP from adenosylcobinamide-GDP ASD06_RS07640 degradation II nucleotide molybdopterin desulfurase]-S- NAD D-ribose 5-phosphate α dihydroguanosine thiamine- S-methyl-5'- pyrophosphohydrolase: undecaprenyl-diphospho-N 3 α-D-glucopyranose 6-O- -mycolyl- 5'-nucleotidase: UDP-N-acetyl-α-D-glucosamine 5-amino-4- + an N -methyladenine + a [protein]-L- RS03490 synthase] sulfanyl-L-cysteine 10 a plastoquinone H H a [protein] Ser/Thr acetamide 5'-triphosphate phosphate kinase: 2-methyladenine an N -formyltetrahydrofolate thioadenosine -acetylmuramoyl-L-alanyl-γ- PRPP NAD(P)H FMN NADH CTP 1-phosphate ω Ins(1)P trehalose 6- ASD06_RS10615 adenine S-methyl-5'- ASD06_RS11120 imidazolecarboxyamide in DNA proline ( = 180) cyclic pyranopterin 5-methylbenzimidazolyl ASD06_RS00450 β nicotinate-nucleotide-- sulfo-bis(guanylyl dCTP dCMP serine/threonine peptidylprolyl amidase: phosphate 1-( -D nicotinate-nucleotide-- D-glutamyl-L-lysyl- D-alanine inositol monophosphate adenosylcobamide biosynthesis dimethylbenzimidazole long-chain fatty thioadenosine protein kinase: ASD06_RS15305 trehalose- thiamine ribofuranosyl) molybdopterin) a (2E)-dodec- undecaprenyldiphospho- isomerase: from adenosylcobinamide-GDP dimethylbenzimidazole phosphoribosyltransferase: acid activation phosphorylase: adenine NAD(P)H-quinone DNA-3- glucose-1-phosphate monophosphatase: phosphatase: synthase diphosphate nicotinamide cofactor dUTP diphosphatase: dut flavin reductase: ASD06_RS14885 ASD06_RS16655 amidase: a thiocarboxylated phosphoribosyltransferase: cobT 2-enoyl-[acp] ASD06_RS14310 muramoylpentapeptide beta-N- phosphoribosyltransferase: dehydrogenase: methyladenine cytidylyltransferase: ASD06_RS07410 otsB MoaC: moaC 5-methylbenzimidazole ASD06_RS09980 [+ 4 isozymes] [+ 3 isozymes] ASD06_RS00630 [small subunit of cyclic cobT NAD salvage pathway I (PNC VI cycle) a long-chain 5-MTR-1-P nucleotide acetylglucosaminyltransferase: ASD06_RS06985 ASD06_RS02920 glycosylase I: ASD06_RS14725 α, α'-trehalose RS13715 nicotinate-nucleotide-- adenine ribotide 2-methyladenine enoyl-ACP a [protein] (L-serine/L- a [protein]-L- myo-inositol fatty acid pyrophosphohydrolase: murG acetate α molybdopterin pyranopterin reductase long-chain fatty ASD06_RS10050 threonine) phosphate proline (ω = 0) 6- -mycolate dimethylbenzimidazole phosphate ribotide phosphate ASD06_RS11120 synthase] phosphate + FabI: fabI acid--CoA ligase: phosphoribosyltransferase: NAD dUTP dUMP + CDP-α-D-glucose benzimidazolyl adenosylcobamide ditrans,octacis-undecaprenyldiphospho- UDP + FMNH NAD thiamine diphosphate adenosylcobinamide- adenosylcobinamide- ASD06_RS15230 AICAR a plastoquinol NAD(P) 2 cobT biosynthesis from enoyl-ACP N-acetyl-(N-acetylglucosaminyl)muramoyl- an apurinic site 5-methylbenzimidazole biosynthesis I (E. coli) GDP GDP [+ 5 isozymes] 3-methyladenine dipyrromethane NAD(+) adenosylcobinamide-GDP reductase: a long-chain Carbohydrate Degradation L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine within DNA ribotide phosphate ribazoletransferase: ribazoletransferase: NAD+ synthase: 5-hydroxy-CTP 5-hydroxy-CMP cofactor biosynthesis 2-[(2R,5Z)- diphosphatase: ASD06_RS08065 fatty acyl-CoA RS03560 ASD06_RS11720 ASD06_RS12140 benzimidazole molybdopterin adenosylcobinamide- 2-carboxy-4- α α α α ASD06_RS11720 NAD+ synthase: Co -[ -(adenin- Co -[ -(2- nudC nicotinate-nucleotide-- Entner-Doudoroff pathway I α undecaprenyl-diphospho-N-acetylmuramoyl-L- GDP an apo-[hydroxymethylbilane methylthiazol-5(2H ASD06_RS12140 a dodecanoyl-[acp] D-mannose degradation UDP-N-acetyl- -D-glucosamine + + 3,4-dihydroxyphenylacetyl- 4-fumaryl- a [release factor]- (2R,3S)-3- 9-yl)]-Coβ- methyladenin-9-yl)]-Co γ H hydrogencarbonate phylloquinone NAD(P)H H trans-aconitate acetyl-CoA acryloyl-CoA synthase]-L-cysteine dimethylbenzimidazole alanyl- -D-glutamyl-L-lysyl- D-alanyl-D-alanine CoA acetoacetate isopropylmalate gly ribazoletransferase: )-ylidene]ethyl adenosylcobamide β nicotinate adenine NMN D-glucopyranose L-glutamine HMP-PP -adenosylcobamide phosphoribosyltransferase: D-mannopyranose peptide chain acetyl-CoA crotonyl-CoA ASD06_RS11720 phosphate 5'-phosphate dinucleotide 6-phosphate undecaprenyldiphospho- trans-aconitate 2- 3-isopropylmalate glycine α α 5'-phosphate cobT beta-ketoacyl- 6-phosphate release factor carboxylase biotin carboxylase/ Co -[ -(5- a [hydroxymethylbilane mannose-6- muramoylpentapeptide beta-N- carbonic NAD(P)H-quinone hydroxyphenylacetyl- methyltransferase: dehydratase: nicotinate-nucleotide benzimidazole ACP synthase glucose-6- fumarylacetoacetase: N(5)-glutamine carboxylase subunit: reductase: oxidase RS14915 folate polyglutamylation methylbenzimidazolyl)]- synthase] ES intermediate thiamine phosphate acetylglucosaminyltransferase: anhydrase: dehydrogenase: CoA thioesterase ASD06_RS14620 leuD leuC 2 adenylyltransferase: ribotide phosphate phosphate ThiO: thiO Coβ-adenosylcobamide phosphate II: fabF fahA methyltransferase: (E)-3- ASD06_RS08750 (2S)-2- ccrA α α α α laurate isomerase: murG ASD06_RS03695 ASD06_RS02920 PaaI: paaI (R)-methylmalonyl- 5'-phosphate hydroxymethylbilane Co -[ -(adenin- Co -[ -(2- ASD06_RS04110 adenosylcobinamide- dehydrogenase: D-xylose prmC (methoxycarbonyl) malonyl-CoA isopropylmalate glyoxylate a tetrahydrofolate synthase: ASD06_RS17400 5 synthase: hemC 7-yl)]-Coβ- methyladenin-7-yl)]-Co GDP S-adenosyl-L- ASD06_RS06225 degradation I a [release factor]-N pent-2-enedioate CoA ASD06_RS04060 a 3-oxotetradecanoyl- long-chain fatty F6P (3,4- adenosylcobamide β-adenosylcobamide NaMN nicotinamide ribazoletransferase: methionine salvage II 6-phospho C1 Compound Utilization and Assimilation ditrans,octacis-undecaprenyldiphospho-N- UDP -methyl-L-glutamine a [hydroxymethylbilane [acp] acid--CoA ligase: CO H O NAD(P) + phylloquinol coenzyme A acetoacetate fumarate nicotinamidase: D-glucono- D-xylose acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L- 2 2 dihydroxyphenyl) bifunctional serine α α synthase] ES intermediate ASD06_RS11720 MscL Co -[ -(5- 3 thiamine ASD06_RS10620 Coα-[α-(benzimidazolyl) 3-oxoacyl- ASD06_RS01820 1,5-lactone xylose isomerase: alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine acetate folylpolyglutamate hydroxymethyltransferase: SAH formaldehyde oxidation methylbenzimidazolyl)]- hydroxymethylbilane phosphate ]-Coβ-adenosylcobamide [acyl-carrier- [+ 5 isozymes] ASD06_RS07325 formaldehyde formaldehyde 10 6-phosphogluconolactonase: synthase/ ASD06_RS16480 an N - Coβ-adenosylcobamide nicotinate adenosylhomocysteinase: II (glutathione-dependent) synthase: hemC thiamine- thiamine diphosphate 5'-phosphate protein] D-xylulose oxidation III oxidation V dihydrofolate serine formyltetrahydrofolate molybdenum cofactor biosynthesis lauroyl-CoA pgl D-cellobiose a 3,5,7,9,11,13,15- phosphoribosyltransferase: ASD06_RS02480 reductase: (mycothiol-dependent) (bacillithiol-dependent) UDP-N-acetyl-α-D-muramoyl- a β-D-galactoside a single- melibionate (S)-2- synthase: a [hydroxymethylbilane phosphate kinase: biosynthesis II (Bacillus) formaldehyde D-alanyl-D-alanine 6'-phosphate hepta-oxo- 4-guanidinobutyramide cerotoyl-CoA wound RNA D-ala hydroxymethyltransferase: bifunctional ASD06_RS10625 D-gluconate xylulokinase: L-alanyl-γ-D-glutamyl-L-lysine stranded RNA hydroxyglutarate synthase] ES intermediate ASD06_RS00450 2-(2-carboxy-4- L-homocysteine fabG amidase: ASD06_RS03970 ASD06_RS01195 4 molybdopterin nicotinate 6-phosphate xylB formaldehyde formaldehyde hexadecanoyl-[PKS-acp]aldo/keto propionyl-CoA L-2- ATP- folylpolyglutamate a (3R)-3- ASD06_RS15305 glycine hydroxymethylbilane thiamine methylthiazol-5- Coα-[α-(benzimidazolyl) phosphogluconate alpha- reductase: carboxylase hydroxyglutarate dependent synthase/ bis(guanylyl molybdenum HMP-PP molybdate methionine synthase: metH hydroxytetradecanoyl- D-xylulose UDP-N-acetylmuramoyl- beta-glucosidase: 6-phospho-beta- polyribonucleotide oxidase synthase: hemC diphosphate yl)ethyl phosphate molybdopterin ]-Coβ-adenosylcobamide S-(hydroxymethyl) ASD06_RS16335 amidase: subunit beta: RNA helicase a tetrahydrofolate a 5,10- dihydrofolate cofactor) biosynthesis methionine synthase: [acp] dehydratase: 5-phosphate glucosidase: nucleotidyltransferase: galactosidase: oxidase: lhgO adenylyltransferase: glutathione S-(hydroxymethyl) S-(hydroxymethyl) tripeptide--D-alanyl- ASD06_RS09435 ASD06_RS00630 ASD06_RS04860 HrpA: hrpA ThiO: thiO methylenetetrahydrofolate synthase: MoO - a holo-[hydroxymethylbilane menaquinol-7 biosynthesis ASD06_RS00775 ASD06_RS14005 ASD06_RS14560 ASD06_RS12970 ASD06_RS03190 9-hydroxy-3,5,7,11,13,15-[+ 7 isozymes] 2 D- alanine ligase: 2-carboxycerotoyl- 2-oxoglutarate thiamine ASD06_RS14420 glutathione- mycothiol bacillithiol 4-guanidinobutanoate an unwound RNA pyruvate bifunctional ASD06_RS03970 molybdopterin synthase] stearate biosynthesis ASD06_RS12510 hexaoxohexadecanoyl- CoA molybdopterin phosphate molybdopterin all-trans- menaquinol-11 biosynthesis met dependent S-(hydroxymethyl) S-(hydroxymethyl) folylpolyglutamate 10 II (bacteria and plants) KDGP a non galactosylated α-D- [PKS-acp] an N - cofactor synthase: adenine 1,4-dihydroxy- D-galactopyranose D-glucopyranose menaquinol-10 biosynthesis molybdate heptaprenyl formaldehyde mycothiol mycothiol D-glucopyranose a nucleoside a single- D-gluconate synthase/ formyltetrahydrofolate all-trans- glutathione a (2E)-tetradec- α galactose acceptor galactopyranose ASD06_RS04060 dinucleotide diphosphate 2-naphthoate methionine melibiose degradation dehydrogenase: dehydrogenase: dehydrogenase: UDP-N-acetyl- -D-muramoyl-L-alanyl- 6-phosphate diphosphate stranded RNA NAD dihydrofolate molybdenum cofactor undecaprenyl 1,4-dihydroxy- 2-enoyl-[acp] a palmitoyl-[acp] all-trans- biosynthesis adenosyltransferase: bifunctional ASD06_RS14815 ASD06_RS14955 ASD06_RS14955 γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine synthase: guanylyltransferase: 2-naphthoate phosphorylation and tetrahydrofolate salvage from 1,4-dihydroxy- diphosphate enoyl-ACP beta-ketoacyl- ASD06_RS16160 decaprenyl thiamine molybdopterin 1,4-dihydroxy- ASD06_RS06725 4-hydroxy-2- melibiose transhydrogenation ASD06_RS03970 5,10-methenyltetrahydrofolate reductase ACP synthase S-formylglutathione S-formylmycothiol S-formylbacillithiol diphosphate 2-naphthoate phosphate molybdotransferase 2-naphthoate cys glu oxoglutarate a 3-methyl-branched DNA combined with an N-terminal L- a double-stranded (S)-3- + a 5,10- 1,4-dihydroxy- FabI: fabI II: fabF D-glucopyranose maltopentaose fumarate stachyose a phosphate NAD cytidylyl molybdenum a 5,10- MoeA: polyprenyltransferase: SAM a 3-oxooctadecanoyl- aldolase/2- 2-oxoglutarate 2,3,4-saturated exogenous DNA to form asp alanyl-[S18 protein oligonucleotide aminobutanoyl- oxaloacetate crotonyl-CoA methylenetetrahydrofolate bis(molybdenum thiamine- 2-naphthoate alpha-galactosidase: monoester NAD kinase: cofactor sulfurylation methenyltetrahydrofolate 1,4-dihydroxy- ASD06_RS14410 ASD06_RS09045 enoyl-ACP [acp] dehydro-3-deoxy- fatty acyl-CoA a recombinational junction of 30S ribosome] CoA crotonyl-CoA cofactor) bifunctional phosphate kinase: polyprenyltransferase: Holliday junction ribosomal protein alkaline ASD06_RS07540 2-naphthoate glutamate-- demethylmenaquinol- reductase: phosphogluconate ASD06_RS03190 oligoribonuclease: 3-aminobutyryl-CoA citrate synthase 2: carboxylase/ cytidylyl molybdenum molybdenum cofactor methylenetetrahydrofolate ASD06_RS00450 MoO - ASD06_RS09045 cysteine ligase: 3-oxoacyl- 4-alpha- resolvase RuvX: ruvX alpha- S18-alanine N- phosphatase: NADP + polyprenyltransferase: 2 8 biosynthesis I ASD06_RS08065 aldolase: phytanoyl-CoA L-aspartate orn ammonia-lyase: ASD06_RS13985 reductase: cofactor (trioxo) guanylyltransferase: dehydrogenase/ molybdopterin demethylmenaquinol-7 [acyl-carrier- formate formate formate glucanotransferase: crossover junction galactosidase: acetyltransferase: phoA ASD06_RS09045 thiamine ASD06_RS05440 all-trans- ASD06_RS04440 D-galactopyranose D-glucopyranose dioxygenase: oxidase: ASD06_RS05575 ccrA ASD06_RS16160 methenyltetrahydrofolate diphosphate cofactor protein] malQ endodeoxyribonuclease ASD06_RS03190 an N-terminal N-acetyl-rimI a nucleoside 5'- (2S,3S)-2- NAD(P) demethylmenaquinol- demethylmenaquinone DMKH2-11 1,4-dihydroxy- octaprenyl a myristoyl-[acp] ASD06_RS02000 ASD06_RS09515 crotonyl-CoA (2S)- an alcohol an [MCD cofactor bis(guanylyl cyclohydrolase: γ reductase: bifunctional resolution of recombinationalRuvC: ruvC L-alanyl-[S18 protein monophosphate methylcitrate transhydrogenase 6 biosynthesis I -L-glutamyl- 2-naphthoate diphosphate ethylmalonyl-CoA molybdopterin) DMKH2-10 methyltransferase: fabG α of 30S ribosome] chaperone]-MCD 10 ASD06_RS07640 demethylmenaquinone L-cysteine beta-ketoacyl- 4-hydroxy-2- junction formation -D- subunit alpha: all-trans- an N - ASD06_RS08985 a (3R)-3- a 2-hydroxy-3-methyl- maltose maltotetraose raffinose cysteine cofactor methyltransferase: ACP synthase oxoglutarate succinate of two intact strands 2-iminosuccinate succinate galactopyranose ASD06_RS15755 hexaprenyl 1,4-dihydroxy- formyltetrahydrofolate demethylmenaquinone 1,4-dihydroxy- hydroxyoctadecanoyl- branched 2,3,4- desulfurase: pyridoxal 5'-phosphate biosynthesis II menaquinol-7 ASD06_RS08985 II: fabF aldolase/2- Alcohol Degradation diphosphate 2-naphthoate methyltransferase: 2-naphthoate [acp] saturated fatty acyl-CoA NADPH ASD06_RS00795 phosphoribosylglycinamide dehydro-3-deoxy- ASD06_RS08985 polyprenyltransferase: formyltransferase: menaquinol-11 a 3-oxohexadecanoyl- phosphogluconate a [cytidylyl molybdenum glutathione ASD06_RS09045 ethanol 1,4-dihydroxy- ASD06_RS07655 [acp] ethanol 1402 6-O-cis-keto- cofactor chaperone]- bis(guanylyl tungstenpterin) menaquinol-10 aldehydo-D-ribose D-glyceraldehyde gln aldolase: eda glycerol and glycerophosphodiester degradation a cytidine sn-glycerol γ-glutamyl- 2-naphthoate degradation II coenzyme A an apo [peptidyl- D-glucopyranose maltohexaose maltotriose a glucan HMG-CoA raffinose acetate mycolyl-trehalose citrate cytidylyl molybdenum cofactor biosynthesis 5-phosphate 3-phosphate 3-oxoacyl- degradation I in 16S rRNA 3-phosphate isopropylamide polyprenyltransferase: a tetrahydrofolate a (2E)-octadec- carrier protein] 16S rRNA 6-phosphate cofactor (sulfo-dioxo) demethylmenaquinol-8 [acyl-carrier- acetate/propionate L-glyceraldehyde aconitate ASD06_RS09045 acyl carrier guanylyl molybdenum NADP 2-enoyl-[acp] D-glyceraldehyde ethanol glycerol ferredoxin: trehalose- pyridoxal 5'- protein] pyruvate ethanol 4-alpha- 4-alpha- alpha- (cytidine(1402)-2'-O) family kinase: hydratase protein activation cofactor biosynthesis biosynthesis 3-phosphate bifunctional a glycerophosphodiester hydroxymethylglutaryl- 3-phosphate ASD06_RS17700 phosphatase: bis(tungstenpterin) GTP phosphate menaquinol-8 biosynthesis enoyl-ACP bifunctional glucanotransferase: glucanotransferase: galactosidase: -methyltransferase: ASD06_RS13840 AcnA: acnA MoO - menaquinol-9 biosynthesis reductase: type I acetaldehyde- holo-ACP synthase: CoA lyase: reductase: mgrA otsB cofactor 2 acetaldehyde- rsmI demethylmenaquinol-6 menaquinol-6 biosynthesis synthase: + fabG reductase ASD06_RS08140 malQ malQ ASD06_RS03190 a 2'-O- L-glyceraldehyde N-(γ-L-glutamyl) an apo acyl- molybdopterin NAD glyceraldehyde- CoA/alcohol ASD06_RS05125 acetyl phosphate trehalose-cis-keto- D-threo-isocitrate pdxT pdxS a (3R)-3- FabI: fabI glycerophosphodiester CoA/alcohol 1402 3-phosphate -L-alaninol carrier protein cofactor molybdenum cofactor demethylmenaquinol-8 NAD kinase: 3-phosphate dehydrogenase: methylcytidine mono-mycolate molybdenum cofactor demethylmenaquinol-9 hydroxyhexadecanoyl- glycerol phosphodiesterase: dehydrogenase: α demethylmenaquinol-6 holo-ACP synthase: guanylyltransferase: demethylmenaquinone ASD06_RS07540 enoyl-ACP dehydrogenase: adhE -D- in 16S rRNA guanylyltransferase: ASD06_RS08140 demethylmenaquinone [acp] ASD06_RS16355 adhE a holo [peptidyl- maltopentaose maltose a glucan D-glucopyranose sucrose demethylmenaquinone guanylyl ASD06_RS16160 methyltransferase: + reductase: chitobiose degradation acetaldehyde 3',5'-ADP acetoacetate acetyl-CoA galactopyranose ASD06_RS16160 a holo acyl- PLP methyltransferase: NADP gap acetaldehyde carrier protein] methyltransferase: molybdenum ASD06_RS08985 ASD06_RS08065 glycerol kinase glycerophosphodiester carrier protein ASD06_RS08985 ASD06_RS08985 cofactor menaquinol-8 N,N'- GlpK: glpK phosphodiesterase: bis(guanylyl menaquinol-9 13-DPG bifunctional menaquinol-6 a stearoyl-[acp] diacetylchitobiose [+ 2 isozymes] ASD06_RS05545 acetaldehyde- a long-linear p-nitrophenyl-α-D- 1518 1402 tungstenpterin) cofactor a (2E)-hexadec- an apo-[LYS2 L- α adenine / a cytidine adenosyl-cob(III) phosphoglycerate 6'-phosphate CoA/alcohol coenzyme A D-glucopyranose a maltodextrin -D-glucopyranose α an acyl phosphate homogentisate ethanol 2-aminoadipyl- -D-glucan galactopyranoside adenine 1519 in 16S rRNA in 16S rRNA yrinate a,c-diamide D-cysteine 2-enoyl-[acp] kinase: acetate sn-glycerol 3-phosphate dehydrogenase: carrier-protein] 16S rRNA 16S rRNA cobyric acid homogentisate catalase/ enoyl-ACP ASD06_RS06260 D-cysteine acetate--CoA adhE 4-alpha- 4-alpha- alpha- (adenine(1518)-N(6)/ (cytosine(1402)-N(4) acylphosphatase: synthase: 1,2-dioxygenase: peroxidase reductase 3-phospho- N-monoacetylchitobiose adenine(1519)-N(6))- )-methyltransferase ASD06_RS00385 desulfhydrase: stearate ligase: acs acetyl-CoA holo-ACP synthase: glucanotransferase: glucanotransferase: galactosidase: ASD06_RS12050 ASD06_RS10610 HPI: katG FabI: fabI D-glycerate 6'-phosphate dimethyltransferase RsmH: rsmH ASD06_RS00605 acetate--CoA ASD06_RS08140 malQ malQ ASD06_RS03190 an N 4 - 4-maleyl- enoyl-ACP RsmA: rsmA a carboxylate adenosylcobyrate acetaldehyde long-chain fatty phosphoglyceromutase: ligase: acsA 6 1518 methylcytidine 1402 acetoacetate pyruvate reductase: N -dimethyladenine 6-phospho-beta- DHAP 6 1519 acid--CoA ligase: ASD06_RS15015 a holo-[LYS2 L- a short 1,4- /N -dimethyladenine in 16S rRNA ASD06_RS08065 ASD06_RS01820 glucosidase: acetyl-CoA a maltodextrin maltose D-galactopyranose 4-nitrophenol 2-phospho- 3',5'-ADP 2-aminoadipyl- α-D-glucan in 16S rRNA [+ 5 isozymes] ASD06_RS14560 a palmitoyl-[acp] D-glycerate carrier-protein] phosphopyruvate N-acetyl-D- stearoyl-CoA D-glucosamine hydratase: eno glucosamine an (S-diacyl-sn- a plant soluble XLLG xyloglucan a [2-oxoglutarate an L-1- D-glucopyranose D-threo-7,8- a nucleoside (3Z)-hex- 6-phosphate glyceryl)-L-cysteinyl- heteroglycan dehydrogenase E2 protein] oxaloacetate (S)-mandelate pyruvate MeOH phosphoenol phosphatidylethanolamine oligosaccharide dihydroneopterin triphosphate 3-en-1-ol [apolipoprotein] N 6 -dihydrolipoyl-L-lysine pyruvate Inorganic Nutrient Metabolism nucleotide phosphoenolpyruvate CHAT domain- mandelate pyruvate catalase/ palmitate dihydrolipoyl 4-alpha- pyrophosphohydrolase: carboxykinase (GTP) containing protein: racemase: carboxylase: peroxidase pyruvate beta-glucosidase: dihydroneopterin dehydrogenase: apolipoprotein N- glucanotransferase: ASD06_RS11120 : ASD06_RS15865 ASD06_RS06075 ASD06_RS13880 ASD06_RS10335 HPI: katG long-chain fatty kinase: pyk selenate reduction ASD06_RS09435 lpdA assimilatory assimilatory sulfur acyltransferase: lnt malQ aldolase: folB a [2-oxoglutarate phosphoenol (3Z)-hex-3- acid--CoA ligase: nitrate reduction V (assimilatory) a nucleoside 5'- (R)-mandelate oxaloacetate formaldehyde sulfate reduction IV sulfate reduction III reduction II (via en-1-yl acetate ASD06_RS01820 pyruvate monophosphate dehydrogenase E2 pyruvate selenate polysulfide) XXXG xyloglucan protein] N 6 -lipoyl-L-lysine [+ 5 isozymes] a 2-acyl-1-lyso- an N-acyl-(S-diacyl- a plant soluble D-galactopyranose 6-(hydroxymethyl) sulfate sulfate nitrate sulfate maltose oligosaccharide glycolaldehyde S 0 phosphatidylethanolamine sn-glyceryl)-L- heteroglycan -7,8-dihydropterin adenylyltransferase: sulfate palmitoyl-CoA respiratory sulfate cysteinyl-[lipoprotein] ASD06_RS15850 adenylyltransferase: nitrate reductase: adenylyltransferase: sulfate ASD06_RS15850 ASD06_RS15850 narI narH p-nitrophenyl- 55 a polysulfide pyridin-1-ium-3-carboxylate-5- D-glucopyranose maltotetraose XLXG xyloglucan a uridine (S)-4- phosphoenol adenylyltransferase sulfate ASD06_RS09705 sulfate a [LarE]-L-cysteine protoporphyrinogen IX 2-hydroxyisobutyramide ferroheme o (S)-lactate thiocarboxylate mononucleotide oligosaccharide β-D-galactoside in tRNA hydroxymandelate pyruvate subunit CysD: cysD adenylyltransferase adenylyltransferase polysulfide protoporphyrinogen amidase: adenosine 5'- tRNA mandelate lactate 2- subunit CysD: cysD nitrite subunit CysD: cysD reductase oxidase: hemG ASD06_RS15305 heme A synthase: pyruvate phosphoselenate 4-alpha- pseudouridine(55) racemase: monooxygenase: APS APS NrfD: nrfD ATP-dependent beta-glucosidase: beta-glucosidase: ASD06_RS06200 kinase: pyk glucanotransferase: protoporphyrinogen amidase: synthase TruB: truB ASD06_RS08810 sacrificial sulfur ASD06_RS09435 ASD06_RS09435 ASD06_RS13880 phosphoadenylyl- polysulfide malQ oxidase: hemG ASD06_RS00630 a pseudouridine 55 (R)-4- transferase LarE: larE 2-hydroxy-2- ferroheme a acetate pyruvate reductase protoporphyrin IX in tRNA hydroxymandelate sulfate reductase: methylpropanoate selenite ammonium ASD06_RS18195 NrfD: nrfD XXXG xyloglucan pyridin-1-ium-3,5- maltose maltotriose D-galactopyranose D-galactopyranose 4-nitrophenol PAPS a [LarE]-dehydroalanine oligosaccharide sulfite a polysulfide bisthiocarboxylate mononucleotide phosphoadenylyl- glutamine glutamate sulfate reductase: synthetase: synthase assimilatory sulfite an [amino-group carrier protein]- 3-(4- (1R,6R)-6-hydroxy-2- ASD06_RS18195 ASD06_RS00660 large reductase (NADPH) pyridin-1-ium-3,5- 2-amino-6-[1-hydroxyethyl]- XXLG xyloglucan selenodiglutathione a [LarE]-L-cysteine C-terminal-γ-(L-glutamate 5- hydroxyphenyl) succinylcyclohexa-2,4- oxaloacetate reduced riboflavin chorismate (R)-lactate [+ 2 isozymes] subunit: gltB : ASD06_RS18190 dicarboxylate mononucleotide 7-methyl-7,8-dihydropterin oligosaccharide sulfite 2-amino-4-hydroxy-6- semialdehyde-2-yl)-L-glutamateN-acetyl-gamma- pyruvate diene-1-carboxylate isochorismate D-2-hydroxyacid hydrogen sulfide o-succinylbenzoate citrate synthase: flavin reductase: hydroxymethyldihydropteridine glutamyl-phosphate 4-hydroxyphenylpyruvate synthase: dehydrogenase: ATP-dependent beta-glucosidase: synthase: ASD06_RS10005 ASD06_RS09980 gln glu diphosphokinase: folK reductase: dioxygenase: hppD ASD06_RS08990 ASD06_RS10290 sacrificial sulfur [1-(2-amino-7-methyl-4-oxo- ASD06_RS09435 ASD06_RS09005 glutathioselenol an [amino-group carrierASD06_RS12320 protein]- 1,2-dihydroxypropane- transferase LarE: larE 7,8-dihydro-3H-pteridin- riboflavin isochorismate pyruvate C-terminal-γ-(5-phospho- homogentisate 2-succinylbenzoate 1,2,3-tricarboxylate hydrogen sulfide 6-yl)]ethyl diphosphate urea cycle XXXG xyloglucan L-glutamyl)-L-glutamate pyridin-1-ium-3-carboxylate-5- D-galactopyranose a [LarE]-dehydroalanine oligosaccharide thiocarboxylate mononucleotide hydrogen selenide arg polyphosphate 3-methyl-2- 5,10-methylene- a 2-O-(α-D-mannosyl)-1- an [amino-group carrier protein]-C- (2R,3S)-3- CTP a uridine 38-40 in tRNA uroporphyrinogen-III an α-limit dextrin a cytosine in DNA methylglyoxal metabolism ammonium oxobutanoate tetrahydromethanopterin phosphatidyl-1D-myo-inositol terminal-γ-(L-ornithyl)-L-glutamate isopropylmalate argininosuccinate phosphatidylinositol RluA family pseudouridine acetylornithine 4-alpha- cytosine 3-isopropylmalate glyoxalase: dCTP deaminase: long chain lyase: argH glutamine- mannoside uroporphyrinogen 3-methyl-2-oxobutanoate synthase: ASD06_RS12435 transaminase: glucanotransferase: methyltransferase: dehydrogenase: ASD06_RS09115 ASD06_RS17575 polyphosphate hydrolyzing acyltransferase: decarboxylase: hemE hydroxymethyltransferase: tRNA pseudouridine(38- ASD06_RS12305 malQ ASD06_RS07915 ASD06_RS00685 [+ 7 isozymes] carbamoyl- 40) synthase TruA: truA ASD06_RS07055 an [amino-group carrier protein]- a α-limit dextrin UTP L-arginino- panB a 2-O-(6-O-acyl-α-D-mannosyl)- a 5-methylcytosine 4-methyl-2- L-ornithine phosphate 38-40 C-terminal-γ-(L-glutamate 5- coproporphyrinogen III with short branches (R)-lactate RNA degradosome succinate a pseudouridine in tRNA 1-phosphatidyl-1D-myo-inositol in DNA oxopentanoate glyphosate synthase: semialdehyde-2-yl)-L-glutamate polyphosphate degradation II carB carA kinase: 2-dehydropantoate THMPT ASD06_RS15165 glyphosate carbamoyl phosphate ornithine argininosuccinate 2,5-diamino-6-(5- carbamoyltransferase: 10 a double UTP dCTP glycine 4a-hydroxy-N - 3-phenyl-2- uroporphyrinogen-I cytidine D-glucopyranose D-ribofuranose long chain synthase: argG argF phospho-D-ribitylamino) oxidase formyltetrahydrofolate stranded DNA oxopropanoate nucleotide nucleoside deaminase: polyphosphate L-citrulline pyrimidin-4(3H)-one dCTP deaminase: ThiO: thiO bifunctional 4a-hydroxytetrahydrobiopterin pyrophosphohydrolase: ASD06_RS15720 exodeoxyribonuclease 4-hydroxyphenylpyruvate uroporphyrinogen xylose isomerase: ribokinase: ASD06_RS17575 phosphate diaminohydroxyphosphoribosylaminopyrimidine dehydratase: V: recD recC dioxygenase: hppD decarboxylase: hemE ASD06_RS11120 cytidine deaminase: ASD06_RS07325 ASD06_RS03575 acquisition ASD06_RS08595 (aminomethyl) deaminase/5-amino-6-(5-phosphoribosylamino) UMP ASD06_RS03090 dUTP glyoxylate 10 D-ribofuranose phosphonate uracil reductase RibD: ribD an N -formyl- (2-hydroxyphenyl) keto-D-fructose a phosphate 5-amino-6-(5-phospho- a 5'-phosphooligonucleotide coproporphyrinogen I uridine 5-phosphate monoester 7,8-dihydrofolate acetate bifunctional D-ribitylamino)uracil RNase H/acid phosphatase: ASD06_RS04780 phosphate

a reduced plastocyanin an oxidized lipid II (meso queuosine queuosine plastocyanin ammonium phosphate diaminopimelate containing)

cytochrome FtsW RS06090 RS08220 RS03200 RS16440 RS07375 ModB RS18055 RS12945 RS02225 RS18115 RS01920 RS10245 RS12185 RS01625 RS08510 RS04345 RS06115 RS17655 RS17475 RS06930 SecE RS16515 SecF MurJ RS17365 RS00045 RS12225 FtsY RS08695 RS10310 RS00365 RS15190 RS03580 RS09580 c oxidase

lipid II (meso queuosine queuosine ammonium phosphate diaminopimelate O containing) 2 H O 2 This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.