An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000829395Cyc: Lactobacillus hokkaidonensis LOOC260 Cellular Overview Connections between pathways are omitted for legibility. 2-dehydro- ammonium ammonium xanthine an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino glycine betaine 3-deoxy-D- uracil (S)-lactate D-gluconate D-gluconate acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid pro gluconate uracil

predicted predicted predicted predicted ABC ABC ABC ABC RS01485 RS01520 RS08520 RS02070 RS10075 RS03575 RS07760 RS03120 RS07970 RS00910 RS10665 RS02525 RS02495 RS09490 RS09390 transporter transporter RS08675 RS06205 RS06390 RS03595 RS09485 RS03790 transporter transporter RS02960 of an of an of an of an amino acid amino acid amino acid amino acid ammonium ammonium glycine betaine 2-dehydro- uracil uracil an amino an amino (S)-lactate D-gluconate D-gluconate an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino RS10870 pro 3-deoxy-D- acid acid gluconate xanthine acid acid acid acid acid acid acid acid acid acid acid acid acid an amino an amino an amino an amino acid acid acid acid an amino an amino RS00960 acid acid

an amino an amino Metabolic Regulator Fermentation acid acid Biosynthesis RS10520 (Gro-P) -Gro-P- a glycopeptide- a [protein] N- a uracil 1939 Nucleoside and Nucleotide Degradation n UDP-α-D-glucose a 5,10- a uridine 34 D-mannosyl-N 4 a uracil in DNA terminal-formyl- a dicarboxylate a dicarboxylate ppGpp metabolism Polyprenyl Biosynthesis heterolactic fermentation gly ManNAc-GlcNAc- in 23S rRNA ATP methylenetetrahydrofolate in tRNA PP-undecaprenol -(N-acetyl-D- L-methionine 23S rRNA biotin superpathway of pyrimidine an amino an amino Aminoacyl-tRNA Charging glutaminyl-tRNA gln biosynthesis via transamidation glucosaminyl) (uracil(1939)-C(5)) trans, trans-farnesyl β-D-fructofuranose deoxyribonucleosides degradation pyrimidine S-methyl-5'-thioadenosine uracil-DNA acid acid pppGpp geranyl diphosphate -asparagine -methyltransferase RS10995 diphosphate biosynthesis ribonucleosides degradation IV tRNA uridine-5- poly(glycerol- 2 glycosylase: peptide deformylase: bifunctional (p)ppGpp biosynthesis 2'-deoxycytidine degradation carboxymethylaminomethyl(34) phosphate) alpha- LOOC260_RS01455 RlmD: biotin--[acetyl-CoA-a dicarboxylate a dicarboxylate glu S-methyl-5'- LOOC260_RS08045 LOOC260_RS10730 carboxylase] ligase: synthetase/guanosine- IPP cytidine synthesis enzyme MnmG: glucosyltransferase: mannosyl-glycoprotein peptide deformylase: IPP nucleoside deaminase: thioadenosine5'-methylthioadenosine/ uracil-DNA LOOC260_RS11345 biotin RS11275 biotin 3',5'-bis(diphosphate) 3'- guanosine 3'- type 2 isopentenyl- nucleoside deaminase: LOOC260_RS11005 LOOC260_RS10735 endo-beta-N- LOOC260_RS06535 23S rRNA pyrophosphohydrolase: LOOC260_RS08415 adenosylhomocysteine glycosylase: biotin--[acetyl-CoA- diphosphate 5'- diphosphate prenyltransferase: F6P D-glucopyranose LOOC260_RS08415 tRNA uridine-5- poly(glycerol- acetylglucosamidase: (uracil(1939)-C(5)) LOOC260_RS05710 cytidine deaminase: nucleosidase: LOOC260_RS00335 carboxylase] ligase: triphosphate 3'- Delta-isomerase: LOOC260_RS02995 thymidine cytidine deaminase: carboxymethylaminomethyl(34) phosphate) alpha- LOOC260_RS10615 -methyltransferase geranyl LOOC260_RS06635 an N-terminal L- LOOC260_RS09430 [+ 2 isozymes] diphosphatase: LOOC260_RS05145 LOOC260_RS09195 LOOC260_RS09195 formate RlmD: NAD(P) an L-glutamyl- pyrimidine- synthesis GTPase MnmE: glucosyltransferase: methionyl-[protein] H + H + Gln LOOC260_RS05710 diphosphate glucose-6- glucokinase: uridine MTR an apyrimidinic uracil LOOC260_RS03060 transhydrogenase [tRNA ] DMAPP nucleoside LOOC260_RS11010 LOOC260_RS10740 a glycopeptide- N-acetyl-D- a 5- phosphate LOOC260_RS04520 2'-deoxyuridine site in DNA pyrimidine-nucleoside D-mannosyl- glucosamine- methyluracil 1939 biotinyl-5'- Asp-tRNA(Asn) isomerase: phosphorylase: gln prenyltransferase: N 4 -N-acetyl- asparagine deoA phosphorylase: deoA 34 [(2-Glc)-Gro-P] -Gro- in 23S rRNA adenylate /Glu-tRNA(Gln) a 5-carboxymethylaminomethyluridine n UDP LOOC260_RS02995 pgi a 7,8-dihydrofolate D-glucosamine F0F1 ATP amidotransferase: GTP ppGpp uracil in tRNA P-ManNAc-GlcNAc- H + H + glutamine-hydrolyzing thymine synthase LOOC260_RS03040 geranyl pyrimidine- PP-undecaprenol GMP synthase: gatA nucleoside- diphosphate nucleoside LOOC260_RS09170 GTP D-glucopyranose LOOC260_RS03050 phosphorylase: 3 [+ 7 isozymes] diphosphate kinase: pyrophosphokinase: prenyltransferase: an N -methyladenine a ribonucleoside an L-cysteinyl- H + RS00920 H + a 5-phosphooxy- 6-phosphate deoA hydrogen selenide O-acetyl-L-serine H O LOOC260_RS01525 LOOC260_RS06785 LOOC260_RS02995 hypoxanthine in DNA formate triphosphate ATP 2 GTP [tRNA Cys ] L-glutamyl- bifunctional (p)ppGpp glucose-6-phosphate NaMN ammonium UDP kinase: GTP PRPP [tRNA Gln ] synthetase/guanosine- (2E,6E)-farnesyl dehydrogenase: LOOC260_RS05645 pyrophosphokinase: DNA-3-methyladenine 3',5'-bis(diphosphate) 3'- diphosphate LOOC260_RS10195 O-acetylhomoserine anaerobic predicted LOOC260_RS00825 glycosylase I: GTPase aminoacyl-tRNA Asp-tRNA(Asn) pyrophosphohydrolase: 6-phospho uracil 2-deoxy-α-D- aminocarboxypropyltransferase/ ribonucleoside- nicotinate-nucleotide ABC hypoxanthine hydrolase: phosphate phosphate /Glu-tRNA(Gln) LOOC260_RS05710 D-glucono- ribose 1-phosphate LOOC260_RS10335 adenylyltransferase: ObgE: obgE superpathway of purine deoxyribonucleosides degradation cysteine synthase: phosphoribosyltransferase: triphosphate LOOC260_RS01955 transporter amidotransferase: 1,5-lactone DNA-3-methyladenine [+ 6 isozymes] phosphopentomutase: LOOC260_RS06800 LOOC260_RS01990 reductase: nadD of phosphate LOOC260_RS03040 GDP glycosylase I: LOOC260_RS09215 O-acetylhomoserine xanthine LOOC260_RS03535 gatA LOOC260_RS03915 H + gln RS09350 gln aminocarboxypropyltransferase/ phosphoribosyltransferase: nicotinate adenine phosphate cys a tRNA Cys LOOC260_RS03050 2-deoxy-D-ribose 2'-deoxyguanosine GDP D-gluconate 5-phosphate cysteine synthase: LOOC260_RS03005 a 2'- dinucleotide 6-phosphate 2'-deoxyadenosine LOOC260_RS10850 an apurinic site deoxyribonucleoside an L-glutaminyl- 3-methyladenine predicted deoxyribose- within DNA 5'-triphosphate gln RS00905 gln [tRNA Gln ] purine-nucleoside ABC phosphate aldolase: phosphorylase: acetate L-selenocysteine IMP met transporter met LOOC260_RS09220 LOOC260_RS09210 of L- tRNA charging D-ribulose purine-nucleoside CO sulfate RS03350 sulfate methionine 2 5-phosphate D-glyceraldehyde acetaldehyde phosphorylase: 3-phosphate 2'-deoxyinosine N-acetyl-D- serine serine asp Thr ribulose-phosphate LOOC260_RS09210 7,8-dihydrofolate + an L-asparaginyl- an L-cysteinyl- RS02460 phe a tRNA Phe tRNA asp thr a tRNA methanethiol O-acetyl-L- NADPH H glu a (6S)-5- γ-L-glutamyl- gly galactosamine thr thr elongator 3-epimerase: acetaldehyde monoglutamate [tRNA Asn ] [tRNA Pro ] gly a tRNA Gly trp a tRNA Trp met initiator tRNA Met met asn tRNA Asn ile a tRNA Ile purine-nucleoside homoserine formyltetrahydrofolate D-alanine 6-phosphate tRNA Met LOOC260_RS04995 dehydrogenase: sulfate RS01365 sulfate tyr a tRNA Tyr lys a tRNA Lys cys a tRNA Cys leu a tRNA Leu his a tRNA His pro a tRNA Pro arg a tRNA Arg a tRNA Ala ala val a tRNA Val ser a tRNA ser phosphorylase: glu Gln D-xylulose LOOC260_RS09945 phenylalanine- aspartate--tRNA ligase: threonine--tRNA ligase: glu a tRNA gln a tRNA 2-deoxy-α-D- LOOC260_RS09210 dihydrofolate serine serine 5-phosphate O-acetylhomoserine bifunctional bifunctional glutamate- aminoacyl-tRNA N-acetylglucosamine- Cys-tRNA(Pro) RS02465 -tRNA ligase: glycine--tRNA ligase: tryptophan-- methionine-- methionine-- asparagine-- LOOC260_RS05680 isoleucine-- LOOC260_RS09470 acetyl-CoA ribose 1-phosphate reductase: thr thr aminocarboxypropyltransferase/ folylpolyglutamate -cysteine ligase hydrolase: 6-phosphate deacylase: a metal a metal LOOC260_RS04465 LOOC260_RS05625 tyrosine--tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: lysine--tRNA ligase: cysteine--tRNA ligase: leucine--tRNA ligase: tRNA ligase: aspartate--tRNA ligase: histidine--tRNA ligase: proline--tRNA ligase: arginine--tRNA ligase: tRNA ligase: alanine--tRNA ligase: valine--tRNA ligase: threonine--tRNA ligase: serine--tRNA ligase: LOOC260_RS05475 RS06015 phosphoketolase: phosphopentomutase: cysteine synthase: synthase/dihydrofolate GshA/glutathione LOOC260_RS01955 deacetylase: LOOC260_RS09725 cation cation LOOC260_RS04470 LOOC260_RS05630 LOOC260_RS01630 LOOC260_RS01740 LOOC260_RS01775 LOOC260_RS01775 LOOC260_RS02010 LOOC260_RS02210 LOOC260_RS03985 LOOC260_RS05175 LOOC260_RS10525 LOOC260_RS05685 LOOC260_RS05820 LOOC260_RS06155 LOOC260_RS06660 LOOC260_RS07410 LOOC260_RS07550 LOOC260_RS00975 LOOC260_RS10645 dihydrofolate LOOC260_RS09705 LOOC260_RS09215 LOOC260_RS06800 synthase: synthetase GshB: LOOC260_RS02080 inosine 5'-phosphate guanosine nucleotides reductase: met RS10820 met an L-methionyl- phosphoketolase: 2-deoxy-D-ribose degradation degradation III O-acetylhomoserine LOOC260_RS07545 LOOC260_RS09030 an L-phenylalanyl- an L-tyrosyl- an L-tryptophanyl- an L-methionyl- an L-lysyl- an L-cysteinyl- an L-leucyl- an L-asparaginyl- an L-aspartyl- an L-histidyl- an L-prolyl- an L-arginyl- an L-isoleucyl- an L-alanyl- an L-valyl- an L-threonyl- an L-seryl- an L-glutamyl- an L-glutaminyl- LOOC260_RS02260 a glycyl-[tRNA Gly ] [elongator LOOC260_RS05060 5-phosphate aminocarboxypropyltransferase/ asn tRNA Asn cys a tRNA Pro a metal a metal [tRNA Phe ] [tRNA Tyr ] [tRNA Trp ] [initiator tRNA Met ] [tRNA Lys ] [tRNA Cys ] [tRNA Leu ] [tRNA Asn ] [tRNA asp ] [tRNA His ] [tRNA Pro ] [tRNA Arg ] [tRNA Ile ] [tRNA Ala ] [tRNA Val ] [tRNA Thr ] [tRNA ser ] [tRNA Glu ] [tRNA Gln ] D-galactosamine RS08525 tRNA Met ] cysteine synthase: acetate cation cation a (6S)-5- 6-phosphate D-glyceraldehyde deoxyribose- IMP GMP LOOC260_RS10850 5,6,7,8- norophthalmate NADP + formyltetrahydrofolate predicted 3-phosphate acetyl phosphate phosphate aldolase: tetrahydrofolate ABC efflux 5'-nucleotidase: type I glyceraldehyde- LOOC260_RS09220 arsenite RS09145 arsenite thiol transporter thiol Secondary Metabolite Biosynthesis phosphate LOOC260_RS07240 acetate 3-phosphate met of a thiol acetyltransferase: XMP guanosine dehydrogenase: D-glyceraldehyde group Nucleoside and Nucleotide Biosynthesis LOOC260_RS08040 acetaldehyde autoinducer AI-2 biosynthesis I LOOC260_RS08135 3-phosphate purine-nucleoside arsenite RS11125 arsenite predicted acetyl-CoA acetaldehyde 5'-nucleotidase: an inactive superpathway of purine nucleotides de novo biosynthesis I phosphorylase: a reduced a DNA containing an phosphoenol a nucleoside O-phospho- NADH ABC superpathway of guanosine nucleotides de novo biosynthesis II superpathway of inosine-5'-phosphate biosynthesis I purine deoxyribonucleosides salvage 13-DPG dehydrogenase: LOOC260_RS07240 ribonucleoside SAM a ribonucleic acid formate cys SAM LOOC260_RS09210 flavodoxin apurinic/apyrimidinic site dGDP pyruvate triphosphate CTP L-homoserine D-ribose transporter D-ribose adenosine nucleotides guanine and acetaldehyde LOOC260_RS09945 triphosphate of D-ribose Cell Structure Biosynthesis PRPP de novo biosynthesis I guanosine salvage II phosphoglycerate dehydrogenase: reductase Cd 2+ RS00390 Cd 2+ AIR acetyl-CoA xanthosine guanine bifunctional DNA- anaerobic NAD(+) IMP 5-(carboxyamino)imidazole 2'-deoxyguanosine 2'-deoxyadenosine kinase: LOOC260_RS09945 DNA-directed cystathionine amidophosphoribosyltransferase: formamidopyrimidine ribonucleoside- diphosphatase: a purine RS00735 a purine SAH UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing) IMP ribonucleotide synthase: deoxynucleoside deoxynucleoside LOOC260_RS08130 RNA polymerase gamma-synthase: LOOC260_RS05245 asp guanosine acetaldehyde anaerobic glycosylase/ pyruvate kinase: triphosphate LOOC260_RS08845 kinase: kinase: 3-phospho- purine-nucleoside subunit delta: 2+ 2+ LOOC260_RS05220 guanine deaminase: ribonucleoside- DNA-(apurinic or LOOC260_RS05580 LOOC260_RS01810 Cd RS09115 Cd 5'-methylthioadenosine/ UDP-N-acetyl-α-D-glucosamine (R)-glycerate phosphorylase: reductase: 5-phospho-β-D-ribosylamine gly N5-CAIR LOOC260_RS04030 LOOC260_RS04030 LOOC260_RS03570 triphosphate reductase LOOC260_RS01875 β adenosylhomocysteine LOOC260_RS09210 apyrimidinic site) lyase: LOOC260_RS03535 reduced - sulfite RS05915 sulfite UDP-N-acetylglucosamine adenylosuccinate deoxynucleoside deoxynucleoside phosphoglyceromutase: activating protein: [+ 3 isozymes] nucleosidase: 5-(carboxyamino)imidazole xanthine LOOC260_RS04320 nicotinamide D- 1-carboxyvinyltransferase: synthase: guanine kinase: kinase: gpmA LOOC260_RS03540 L-cystathionine AMP LOOC260_RS06635 phosphoribosylamine- XMP ribonucleotide mutase: xanthine pyruvate ribonucleotide chloride RS05965 chloride LOOC260_RS01885 LOOC260_RS10880 LOOC260_RS02500 LOOC260_RS02500 ethanol dGTP dCTP -glycine ligase: LOOC260_RS05215 2-phospho- purine ribonucleosides degradation hypoxanthine dGMP dAMP C1 Compound Utilization a 3'-terminal a ribonucleic acid 2+ 2+ S-ribosyl-L-homocysteine UDP-N-acetylglucosamine an active a 5'-phospho-[DNA] Zn RS01450 Zn LOOC260_RS05265 glutamine-hydrolyzing D-glycerate and Assimilation a flavodoxin unsaturated sugar 1-carboxyvinyltransferase: CAIR phosphoribosyltransferase: 5'-deoxyadenosine met ribonucleoside GMP synthase: adenylo-succinate phosphopyruvate semiquinone S-ribosylhomocysteine LOOC260_RS07710 LOOC260_RS01990 urate triphosphate chloride RS07840 chloride LOOC260_RS09170 hydratase: adenosine formate assimilation into 5,10- GAR phosphoribosylaminoimidazolesuccinocarboxamide urate reductase lyase: UDP-N-acetyl-α-D- adenylosuccinate lyase: xanthine LOOC260_RS05390 methylenetetrahydrofolate LOOC260_RS08185 LOOC260_RS10875 synthase: LOOC260_RS05225 phosphoribosyltransferase: glucosamine-enolpyruvate phosphoribosylglycinamide GMP phosphopyruvate LOOC260_RS03005 2+ formate 34 a carboxy- Mg RS06740 Mg 2+ AI-2 UDP-N- formyltransferase 1: SAICAR dGDP dADP hydratase: a 5,10- a 2-thiouridine RNase III mRNA phosphoenol an L-glutamyl- acetylenolpyruvoylglucosamine formate--tetrahydrofolate adenylated- processing a cytidine 34 lys LOOC260_RS05255 guanylate kinase: AMP LOOC260_RS08085 methylenetetrahydrofolate in tRNA cys dADP pyruvate [tRNA Gln ] IMP GMP ligase: LOOC260_RS05285 [ThiS sulfur- in tRNA Ile2 reductase: LOOC260_RS08015 LOOC260_RS09380 adenylosuccinate lyase: nucleoside- nucleoside- phosphoenol substrate Asp-tRNA(Asn) ala 10 guanosine glu FGAR LOOC260_RS10875 xanthosine adenosine inosine guanosine an N -formyltetrahydrofolate carrier protein] UDP-N-acetyl-α-D-muramate guanylate kinase: diphosphate kinase: diphosphate kinase: pyruvate tRNA uridine-5- /Glu-tRNA(Gln) Mg 2+ RS04165 Mg 2+ adenylate kinase: tRNA lysidine(34) monophosphate (2R,4S)-2-methyl-2,4- phosphoribosylformylglycinamidine LOOC260_RS04950 LOOC260_RS01525 LOOC260_RS01525 carboxymethylaminomethyl(34) Mini-ribonuclease 3: amidotransferase: LOOC260_RS02730 AICAR pyruvate kinase: bifunctional 5,10- synthetase TilS: reductase: dihydroxydihydrofuran-3-one UDP-N-acetylmuramate- glutamate racemase: synthase: LOOC260_RS05230 UDP kinase: UDP kinase: synthesis enzyme MnmG: cysteine desulfurase: LOOC260_RS02215 pyruvate kinase: LOOC260_RS03040 LOOC260_RS05580 purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside methylene-tetrahydrofolate LOOC260_RS01985 LOOC260_RS01060 -L-alanine ligase: LOOC260_RS07360 LOOC260_RS05235 GDP bifunctional LOOC260_RS05645 LOOC260_RS05645 LOOC260_RS11005 LOOC260_RS07565 ribonuclease III: LOOC260_RS05580 gatA phosphorylase: phosphorylase: phosphorylase: phosphorylase: dehydrogenase/5,10- GMP reductase: Peptide RS03665 Peptide LOOC260_RS04305 LOOC260_RS05240 ADP pyruvate [+ 2 isozymes] LOOC260_RS05035 LOOC260_RS03050 phosphoribosylaminoimidazolecarboxamide methylene-tetrahydrofolate tRNA uridine-5- an L-glutaminyl- LOOC260_RS10885 LOOC260_RS09210 LOOC260_RS09210 LOOC260_RS09210 LOOC260_RS09210 34 D-glt formyltransferase/IMP cyclohydrolase dGTP dATP a lysidine Gln FGAM cyclohydrolase: carboxymethylaminomethyl(34) [tRNA ] GMP (2R,4S)-2-methyl-2,3,3,4- UDP-N-acetyl-α-D-muramoyl-L-alanine nucleoside- class 1b ribonucleoside- class 1b ribonucleoside- class 1b ribonucleoside- PurH: LOOC260_RS05260 RNase III pyruvate in tRNA Ile2 L-lactate D-lactate α-D-ribose- LOOC260_RS04890 synthesis GTPase MnmE: a thiocarboxy- tetrahydroxytetrahydrofuran diphosphate kinase: diphosphate reductase: diphosphate reductase: diphosphate reductase: ala an mRNA fragment processing dATP Peptide RS02040 Peptide phosphoribosylformylglycinamidine superpathway of pyrimidine deoxyribonucleoside salvage dehydrogenase: dehydrogenase: 1-phosphate LOOC260_RS11010 AMP [ThiS-Protein] UDP-N-acetylmuramoyl- LOOC260_RS01525 LOOC260_RS08430 LOOC260_RS08430 LOOC260_RS08430 FAICAR a 5,10-methenyltetrahydrofolate product mRNA cyclo-ligase: LOOC260_RS05250 LOOC260_RS08435 LOOC260_RS01950 LOOC260_RS05860 UTP and CTP dephosphorylation I L-alanine--D- UDP kinase: LOOC260_RS08435 LOOC260_RS08435 2'-deoxycytidine phosphopentomutase: bifunctional LOOC260_RS09215 bifunctional 5,10- a 5-aminomethyl-2- glutamate ligase: AIR LOOC260_RS05645 UTP a 7,8-dihydrofolate phosphoribosylaminoimidazolecarboxamide xanthine and 34 Peptide RS09530 Peptide LOOC260_RS06705 dADP (S)-lactate (R)-lactate D-ribose 5- methylene-tetrahydrofolate thiouridine in tRNA formyltransferase/IMP cyclohydrolase nucleoside deaminase: 2'-deoxycytidine xanthosine salvage phosphate dehydrogenase/5,10- α phosphoribosylaminoimidazole dGDP PurH: LOOC260_RS05260 LOOC260_RS08415 kinase: CTP synthase: nucleoside meso-diaminopimelate UDP-N-acetyl- -D-muramoyl- nucleoside- methylene-tetrahydrofolate carboxylase: LOOC260_RS03010 GTP superpathway of guanosine cytidine deaminase: LOOC260_RS04030 LOOC260_RS01880 triphosphate a ring-opened 7- a peptide with 2''-O-acetyl- L-alanyl-D-glutamate cyclohydrolase: + nucleotides de novo biosynthesis I diphosphate kinase: xanthosine methylguanine γ-L-glutamyl-(S)- gly NADPH NAD a RNA-DNA hybrid ADP-ribose formate a sugar RS11480 a sugar asp LOOC260_RS09195 hydrolase: LOOC260_RS04890 an N-terminal UTP CAIR LOOC260_RS01525 IMP dCMP CTP 2-aminobutanoate nucleoside- purine-nucleoside pyruvate fermentation LOOC260_RS03590 in DNA L-proline D-ala UDP-N-acetylmuramoyl- UDP kinase: 2'-deoxyuridine phosphorylase: pyruvate fermentation to (S)-acetoin pyrimidine deoxyribonucleotides L-alanyl-D- anaerobic diphosphate kinase: IMP (d)CMP kinase: nucleoside a 5,10-methylenetetrahydrofolate NAD(P) ribonuclease HI: O-acetyl-ADP- anaerobic phosphoribosylaminoimidazolesuccinocarboxamide LOOC260_RS05645 LOOC260_RS09210 to (R)-acetoin II dephosphorylation UDP bifunctional glutamate- prolyl aminopeptidase: ribose deacetylase: a sugar RS00255 a sugar D-alanine--D- glutamate--2, 6- ribonucleoside- LOOC260_RS01525 LOOC260_RS05525 xanthine triphosphate bifunctional DNA- transhydrogenase: LOOC260_RS05275 ribonucleoside- diaminopimelate ligase: synthase: LOOC260_RS05225 triphosphate thymidine kinase: pyruvate nucleotide hydrolase: formamidopyrimidine -cysteine ligase LOOC260_RS09435 LOOC260_RS00740 alanine ligase A: UDP kinase: dCDP pyruvate LOOC260_RS05070 [+ 2 isozymes] triphosphate dATP LOOC260_RS07805 acetolactate pyrophosphohydrolase: GshA/glutathione LOOC260_RS07620 LOOC260_RS10990 reductase: LOOC260_RS05645 xanthine acetolactate LOOC260_RS03590 glycosylase/ LOOC260_RS05075 proline iminopeptidase: reductase: LOOC260_RS03535 [+ 2 isozymes] thymidine nucleoside- phosphoribosyltransferase: synthase AlsS: LOOC260_RS06395 DNA-(apurinic or synthetase GshB: SAICAR synthase AlsS: dCTP dCMP UMP LOOC260_RS05080 LOOC260_RS00245 LOOC260_RS03535 a sugar RS02230 a sugar UDP-N-acetyl-α-D-muramoyl-L-alanyl- diphosphate kinase: LOOC260_RS04135 CDP LOOC260_RS09030 a nucleoside 5'- acetate ADP-D-ribose D-alanyl-D-alanine LOOC260_RS03005 LOOC260_RS04135 apyrimidinic site) lyase: DNA γ-D-glutamyl-meso-2,6-diaminopimelate adenine and dUMP LOOC260_RS01525 (S)-2-acetolactate 5'-nucleotidase: monophosphate adenylosuccinate lyase: XMP thymidine kinase: (S)-2-acetolactate LOOC260_RS04320 adenosine salvage I dUTP diphosphatase: LOOC260_RS07240 dUTP LOOC260_RS10875 LOOC260_RS07805 UDP kinase: NADH NADP + a peptide pro UDP-N-acetylmuramoyl- thymidylate synthase: XMP LOOC260_RS02190 glutamine-hydrolyzing [+ 2 isozymes] LOOC260_RS05645 acetolactate CMP uridine 2,6-diamino-4- ophthalmate a sugar RS09320 a sugar tripeptide--D-alanyl- LOOC260_RS05480 [+ 2 isozymes] a 5'-phospho- a 3'-phospho- AICAR GMP synthase: adenosine decarboxylase: hydroxy-5-(N-methyl) 4-oxo-2-pentenal D- alanine ligase: dCTP pyrimidine ribonucleosides salvage I dUTP dUMP 5'-nucleotidase: [DNA] [DNA] LOOC260_RS09170 purine-nucleoside LOOC260_RS04140 diacetyl formamidopyrimidine LOOC260_RS01920 bifunctional LOOC260_RS07240 phosphorylase: cytidine a sugar RS01380 a sugar phosphoribosylaminoimidazolecarboxamide (R)-acetoin α dGTP GMP LOOC260_RS09210 acetoin reductase: 5-hydroxy-CMP cytidine UDP-N-acetyl- -D-muramoyl-L- formyltransferase/IMP cyclohydrolase 5-hydroxy-CTP a peptidoglycan a nascent peptidoglycan a [DNA]-3'- a 5'-phospho- a 1-acyl-2- 3''-O-acetyl- γ adenine LOOC260_RS10860 + sn-glycerol alanyl- -D-glutamyl-meso-2,6- nucleoside deaminase: NAD ADP-ribose sec PurH: LOOC260_RS05260 dTMP pyrimidine deoxyribonucleotides de novo biosynthesis I with (L-alanyl-γ-D- with (L-alanyl-γ-D- hydroxyl [DNA] ATP arachidonoyl- 3-phosphate ser a tRNA diaminopimeloyl-D-alanyl-D-alanine guanylate kinase: LOOC260_RS08415 acetoin reductase: a tRNA precursor sn-glycerol CTP dTMP kinase: glutamyl-meso-2,6- glutamyl-meso-2,6- a sugar RS09930 a sugar FAICAR LOOC260_RS09380 adenine UDP CTP cytidine deaminase: CMP LOOC260_RS03945 CTP 3-phosphate CTP LOOC260_RS08390 diaminopimeloyl-D- diaminopimeloyl-D- O-acetyl-ADP- guanylate kinase: phosphoribosyltransferase: class 1b ribonucleoside- NAD- nucleoside LOOC260_RS09195 (S)-acetoin alanine) tetrapeptide alanine) tetrapeptide glycerol-3-phosphate ribose deacetylase: bifunctional LOOC260_RS04950 LOOC260_RS06355 dTDP diphosphate reductase: triphosphate Amino Acid Degradation dependent CCA tRNA cytidylyltransferase: serine--tRNA ligase: phosphoribosylaminoimidazolecarboxamide UMP biosynthesis II DNA ligase phosphatidate LOOC260_RS00740 LOOC260_RS10645 nucleoside- LOOC260_RS08430 hydrolase: uridine nucleotidyltransferase: cytidylyltransferase: LOOC260_RS03340 formyltransferase/IMP cyclohydrolase GDP AMP LOOC260_RS08435 LOOC260_RS03590 L,D-transpeptidase: LigA: ligA diphosphate kinase: uridine kinase: L-threonine degradation I LOOC260_RS05490 LOOC260_RS05830 PurH: LOOC260_RS05260 dUDP CDP L-leucine degradation IV (Stickland reaction) L-serine degradation LOOC260_RS06125 LOOC260_RS01525 acetate ADP-D-ribose gln hydrogencarbonate LOOC260_RS04480 an L-seryl- nucleoside- a tRNA CDP-glycerol UDP kinase: class 1b ribonucleoside- Respiration [DNA] NMN a CDP-1-acyl- sec Fatty Acid and Lipid Biosynthesis IMP UMP thr [tRNA ] nucleoside- class 1b ribonucleoside- LOOC260_RS05645 diphosphate kinase: diphosphate reductase: leu ser a nascent peptidoglycan AMP containing a 2-arachidonoyl- bifunctional threonine carbamoyl- diphosphate kinase: diphosphate reductase: LOOC260_RS01525 LOOC260_RS08430 bifunctional threonine with L,D cross links D-ala 3' CCA end glycerol dTTP 2-oxoisovalerate decarboxylation to isobutanoyl-CoA ammonia-lyase/L- palmitate biosynthesis II (bacteria and plant cytoplasm) phosphate synthase: LOOC260_RS01525 LOOC260_RS08430 UDP kinase: LOOC260_RS08435 ammonia-lyase/L- (meso-diaminopimelate serine ammonia- phosphatidylglycerol stearate biosynthesis LOOC260_RS00140 UDP kinase: LOOC260_RS08435 LOOC260_RS05645 an [apo BCAA serine ammonia- containing) dCDP lyase TdcB: biosynthesis I (plastidic) II (bacteria and plants) LOOC260_RS00145 LOOC260_RS05645 CMP phosphorylation dehydrogenase lyase TdcB: an acetoacetyl-[acp] dUTP 6 LOOC260_RS09495 4-methyl-2- nucleoside- E2 protein] N branched-chain (2Z)-2-aminobut- LOOC260_RS09495 [+ 2 isozymes] CMP 2-aminoprop- a 7,8-dihydro- a [ThiI sulfur- luteolin 7-O-[β-D- a dipetide with an N- DHAP a palmitoyl-[acp] dUTP diphosphatase: diphosphate kinase: -lipoyl-L-lysine oxopentanoate an L-aspartyl- dGDP alpha-keto acid 2-enoate 8-oxoguanine carrier protein]- cys glucosyluronate-(1,2)-β- methylsalicylate glu ala acetoacetyl- NAD(P)H-dependent LOOC260_RS01525 (d)CMP kinase: branched-chain D-2- 2-enoate terminal L-aspartate [tRNA Asn ] beta-ketoacyl-[acyl- carbamoyl GTP LOOC260_RS02190 dehydrogenase: in DNA [acp] reductase: glycerol-3-phosphate asp LOOC260_RS05525 alpha-keto acid L-cysteine D-glucosiduronate]-4'- Asp-tRNA(Asn) carrier-protein] nucleoside- [+ 2 isozymes] UDP kinase: LOOC260_RS06520 hydroxyisocaproate β LOOC260_RS11305 dehydrogenase: phosphate CDP O- -D-glucosiduronate /Glu-tRNA(Gln) synthase II: XMP diphosphate kinase: LOOC260_RS05645 dehydrogenase LOOC260_RS06525 dehydrogenase: dipeptidase: a (3R)-3- LOOC260_RS08225 superpathway of adenosine nucleotides de novo biosynthesis II dUMP carboxylesterase: glutamate-- LOOC260_RS11310 LOOC260_RS01525 nucleoside- subunit E2: LOOC260_RS09255 bifunctional DNA- cysteine desulfurase: LOOC260_RS09815 amidotransferase: hydroxybutanoyl- sn-glycerol a 3-oxooctadecanoyl- aspartate dCTP 2-iminobutanoate LOOC260_RS08065 cysteine ligase: thymidylate synthase: diphosphate kinase: LOOC260_RS06520 (R)-2-hydroxy-4- 2-iminopropanoate formamidopyrimidine LOOC260_RS07565 beta-glucuronidase: LOOC260_RS03040 [acp] 3-phosphate [acp] glutamine-hydrolyzing carbamoyltransferase UDP kinase: dipeptidase PepV: LOOC260_RS09655 LOOC260_RS05480 LOOC260_RS01525 dihydrolipoyl methylpentanoate glycosylase/ [+ 2 isozymes] LOOC260_RS10140 gatA beta-hydroxyacyl- glycerol-3-phosphate GMP synthase: catalytic subunit: LOOC260_RS05645 IMP LOOC260_RS04005 (R)-3-hydroxystearoyl- asp dTMP UDP kinase: dehydrogenase:an [apo BCAA an [apo BCAA dehydrogenase DNA-(apurinic or LOOC260_RS03050 ACP dehydratase: acyltransferase: LOOC260_RS09170 LOOC260_RS10780 an L-asparaginyl- salicylate MeOH [acp] reductase: LOOC260_RS05645 LOOC260_RS06515dehydrogenase E2 protein] N 6 -S-[2- apyrimidinic site) lyase: a [ThiI sulfur- γ-L-glutamyl- LOOC260_RS11320 LOOC260_RS05415 dGTP dTMP kinase: [tRNA Asn ] LOOC260_RS11305 asp 6 LOOC260_RS04320 ala carrier protein]- luteolin 7-O-β- a 1-acyl-sn GMP E2 protein] N - methylpropanoyl]dihydrolipoyl- 2-oxobutanoate 4-methylpentanoyl- β-D-glucuronate a proteinogenic asp D-alanine 3-hydroxyacyl-[acyl- a (3R)-3- adenylosuccinate synthase: LOOC260_RS08390 CTP pyruvate L-tryptophan D-diglucuronide N-carbamoyl- dihydrolipoyl-L-lysine L-lysine CoA S-sulfanyl- amino acid carrier-protein] -glycerol 3- hydroxyoctadecanoyl- adenylosuccinate LOOC260_RS10880 degradation IV (via guanylate kinase: L-aspartate dTDP a 5'-phospho- a 3'-phospho- 7,8-dihydro- L-cysteine dehydratase FabZ: phosphate [acp] synthase: enoyl-[acyl- indole-3-lactate) 4-oxo-2-pentenal 1-acyl-sn-glycerol- beta-hydroxyacyl- LOOC260_RS09380 nucleoside- [DNA] [DNA] 8-oxoguanine LOOC260_RS11280 LOOC260_RS10880 dihydroorotase: adenylo-succinate carrier-protein] 3-phosphate ACP dehydratase: diphosphate kinase: trp guanylate kinase: LOOC260_RS10775 superpathway of pyrimidine propanoyl-CoA reductase FabV: a (2E)-but- acyltransferase: LOOC260_RS11320 LOOC260_RS04950 adenylo-succinate LOOC260_RS01525 superpathway of 5-aminoimidazole branched-chain aromatic amino acid amidohydrolase/ nucleobases salvage adenylosuccinate lyase: LOOC260_RS09850 (R)-2-hydroxy-4- a mature peptidoglycan an N-formyl-L- 2-enoyl-[acp] LOOC260_RS05875 ribonucleotide biosynthesis alpha-keto acid aminotransferase: a Xaa-Pro dipeptidyl- an N-modified acibenzolar- all-trans- 3-hydroxyacyl-[acyl- deacetylase family UDP kinase: 4-methylpent- methylpentanoyl- (meso-diaminopimelate methionylaminoacyl- a protein LOOC260_RS10875 peptidase substrate aminoacyl-[tRNA] S-methyl retinyl palmitate enoyl-[acyl- 1-acyl-sn-glycerol- GDP adenylosuccinate lyase: uracil LOOC260_RS05645 dehydrogenase 2-enoyl-CoA LOOC260_RS09360 containing) carrier-protein] metallohydrolase: PRPP CoA tRNA ATP-dependent carrier-protein] LOOC260_RS10875 uracil subunit E2: [+ 2 isozymes] 3-phosphate dehydratase FabZ: LOOC260_RS02825 dTTP (indol-3- Clp protease reductase FabI: phosphoribosyltransferase: AMP amidophosphoribosyltransferase: LOOC260_RS06520 propanoyl acyltransferase: LOOC260_RS11280 yl)pyruvate endolytic Xaa-Pro dipeptidyl- aminoacyl-tRNA carboxylesterase: carboxylesterase: proteolytic subunit: LOOC260_RS11340 (S)-dihydroorotate LOOC260_RS07780 LOOC260_RS05245 phosphate peptide deformylase: LOOC260_RS02290 β transglycosylase MltG: hydrolase: LOOC260_RS08065 LOOC260_RS08065 a 1,2-diacyl- a (2E)-octadec- AMP 5-phospho- - LOOC260_RS01455 peptidase: LOOC260_RS08150 bifunctional pyr operon acetate kinase: L-threonine LOOC260_RS04475 LOOC260_RS01955 a butanoyl-[acp] sn-glycerol 2-enoyl-[acp] dihydroorotate adenylate kinase: D-ribosylamine L-glutamine peptide deformylase: LOOC260_RS09420 Clp protease ClpP: transcriptional regulator/uracil Macromolecule Modification LOOC260_RS07250 degradation II 3-phosphate class 1b ribonucleoside- dehydrogenase: LOOC260_RS02730 phosphoribosylamine- degradation I LOOC260_RS06535 LOOC260_RS04740 enoyl-[acyl- adenylate kinase: phosphoribosyltransferase guanine and (R)-3-(indol- acibenzolar MeOH palmitate a retinol beta-ketoacyl-[acyl- phosphatidate diphosphate reductase: LOOC260_RS10760 -glycine ligase: a mature peptidoglycan a mature peptidoglycan a dipeptide with a a peptide carrier-protein] nucleoside- LOOC260_RS02730 PyrR: LOOC260_RS10785 guanosine salvage propanoate thr 3-yl)lactate an N-modified an uncharged carrier-protein] cytidylyltransferase: LOOC260_RS08430 PRPP LOOC260_RS05265 tRNA-uridine 2-thiolation with (L-alanyl-γ-D- strand (non- C-terminal L-proline a peptide reductase FabI: diphosphate kinase: orotate UMP ADP L-threonine 3- gln a L-methionylaminoacyl- amino acid tRNA synthase II: LOOC260_RS05830 LOOC260_RS08435 and selenation (bacteria) L-alanine glutamyl-meso-2,6- reducing terminus) formate LOOC260_RS11340 LOOC260_RS01525 (d)CMP kinase: GAR dehydrogenase: glutamine-hydrolyzing tRNA LOOC260_RS11310 ADP guanosine degradation IV diaminopimeloyl-D- a CDP- UDP kinase: orotate LOOC260_RS05525 class 1b ribonucleoside- class 1b ribonucleoside- LOOC260_RS09475 GMP synthase: a stearoyl-[acp] purine-nucleoside phosphoribosylglycinamide phosphoribosylglycinamide L-2-amino-3- alanine) tetrapeptide a 3-oxohexanoyl- diacylglycerol LOOC260_RS05645 phosphoribosyltransferase: diphosphate reductase: diphosphate reductase: cys LOOC260_RS09170 class 1b ribonucleoside- UMP kinase: phosphorylase: formyltransferase 1: L-asparagine oxobutanoate [acp] CDP-diacylglycerol-- LOOC260_RS10750 LOOC260_RS08430 LOOC260_RS08430 formyltransferase 2: [+ 7 isozymes] ala diphosphate reductase: LOOC260_RS05845 LOOC260_RS09210 LOOC260_RS05220 LOOC260_RS05255 cysteine desulfurase: degradation I glycine C- glu glycerol-3-phosphate 3- LOOC260_RS08435 LOOC260_RS08435 alanine a 2-deoxy-D- luteolin 7-O-β- 3-oxotehexanoyl- LOOC260_RS08430 UDP guanine LOOC260_RS06625 a nucleobase H O a ferricytochrome a carboxylic ester phosphatidyltransferase: acetyltransferase: dehydrogenase: diphosphate 2 a type IV prepilin [acyl-carrier dGDP LOOC260_RS08435 orotidine 5'- FGAR ribosyl-base b formate D-glucuronide dITP [+ 2 isozymes] LOOC260_RS09480 L-aspartate 1 LOOC260_RS07480 phosphate nucleoside-diphosphate dADP asn LOOC260_RS09500 protein] reductase: stearate hypoxanthine an [L-cysteine degradation I non-canonical 1-(3-sn- kinase: LOOC260_RS01525 phosphoribosylformylglycinamidine asparaginase: pyruvate LOOC260_RS11305 dADP ATP phosphoribosyltransferase: desulfurase]-S- gly nucleoside 2- purine NTP a (3R)-3- phosphatidyl) orotidine-5'-phosphate UDP kinase: synthase: LOOC260_RS05230 LOOC260_RS03910 manganese- formate carboxylesterase: beta-glucuronidase: acyl-CoA synthetase: nucleoside- LOOC260_RS01990 sulfanyl-L-cysteine deoxyribosyltransferase: prepilin peptidase: pyrophosphatase: -sn-glycerol GTP decarboxylase: LOOC260_RS05235 asp dependent inorganic LOOC260_RS08065 LOOC260_RS10140 hydroxyhexanoyl- LOOC260_RS01720 diphosphate kinase: LOOC260_RS05645 nucleoside-diphosphate asp dehydrogenase: LOOC260_RS11810 3-phosphate nucleoside- LOOC260_RS10755 xanthine LOOC260_RS05240 aspartate LOOC260_RS06350 pyrophosphatase: LOOC260_RS06245 [acp] LOOC260_RS01525 LOOC260_RS00575 phosphatidylglycerophosphatase acyl-CoA synthetase: diphosphate kinase: UTP kinase: LOOC260_RS01525 anaerobic ribonucleoside- phosphoribosyltransferase: nucleoside 2- LOOC260_RS05395 [+ 2 isozymes] beta-hydroxyacyl- UMP aminotransferase: LOOC260_RS01695 UDP kinase: LOOC260_RS01525 UDP kinase: triphosphate reductase: LOOC260_RS03005 FGAM β ACP dehydratase: A: LOOC260_RS07215 CTP synthase: a [TusA sulfur- LOOC260_RS09260 deoxyribosyltransferase: an alcohol a carboxylate luteolin -D-glucuronate dIMP LOOC260_RS05645 LOOC260_RS05645 LOOC260_RS03535 a cleaved type LOOC260_RS11320 phosphatidylglycerophosphatase stearoyl-CoA UDP kinase: LOOC260_RS01880 carrier protein]-S- oxaloacetate LOOC260_RS01620 a ferrocytochrome a peptide GMP phosphoribosylformylglycinamidine + IV prepilin A: LOOC260_RS10495 LOOC260_RS05645 sulfanyl-L-cysteine phosphate H b 3-hydroxyacyl-[acyl- an L-1- CTP cyclo-ligase: LOOC260_RS05250 1 carrier-protein] long-chain fatty a 2-deoxy-D- phosphatidyl- dGTP a nucleobase dATP dATP ribosyl-base dehydratase FabZ: sn-glycerol acid activation AIR LOOC260_RS11280 a [TusD sulfur- a long-chain carrier protein]-S- Carboxylate Degradation a (2E)-hex- fatty acid a purine base a [lipoyl-carrier a cytidine 1402 acyl-CoA synthetase: sulfanyl-L-cysteine H O O-succinyl-L- (R)-lipoate 2-enoyl-[acp] 2 met LOOC260_RS01695 lesion in DNA ATP homoserine protein]-L-lysine in 16S rRNA XTP cis-vaccenate biosynthesis superpathway of β-D- 16S rRNA enoyl-[acyl- pyruvate decarboxylation to acetyl CoA bifunctional glutamate acyl-CoA synthetase: glucuronosides degradation (cytosine(1402)-N(4) non-canonical carrier-protein] bifunctional DNA- N-acetyltransferase/ a long-chainLOOC260_RS01720 a [TusE sulfur lipoate--protein ligase: )-methyltransferase purine NTP reductase FabI: β a [pyruvate cystathionine amino-acid a palmitoleoyl-[acp] 34 carrier protein]-S a -D-glucuronoside formamidopyrimidine ATPase: LOOC260_RS02965 pyrophosphatase: fatty acyl-CoA Aromatic Compound Biosynthesis a uridine in tRNA dehydrogenase gamma-synthase: RsmH: acetyltransferase ArgJ: LOOC260_RS11340 beta-ketoacyl-[acyl- -sulfanylcysteine glycosylase/ LOOC260_RS11225 [+ 2 isozymes] 6 LOOC260_RS06725 LOOC260_RS06245 beta-glucuronidase: E2 protein] N pyruvate LOOC260_RS01810 an N 4 - LOOC260_RS00155 carrier-protein] Carbohydrate Biosynthesis DNA-(apurinic or [+ 3 isozymes] [+ 2 isozymes] chorismate biosynthesis I -lipoyl-L-lysine dehydrogenase 1402 N-acetyl-L- a hexanoyl-[acp] synthase II: tRNA 2-thiouridine(34) LOOC260_RS10140 apyrimidinic site) lyase: a [lipoyl-carrier methylcytidine dipicolinate biosynthesis (acetyl-transferring) methionine XMP synthase MnmA: 6 in 16S rRNA an (11Z)-3-LOOC260_RS11310 LOOC260_RS04320 + protein]-N - beta-ketoacyl-[acyl- UDP-N-acetyl-D- D-erythrose D-glucopyranuronate dihydrolipoyl E1 component phosphate H succinate oxooctadec- UDP-α-D-glucose PRPP biosynthesis LOOC260_RS06620 ADP L-homocysteine lipoyl-L-lysine carrier-protein] glucosamine biosynthesis I 4-phosphate dehydrogenase: subunit alpha: 11-enoyl-[acp] biosynthesis I 3-deoxy-7- asp LOOC260_RS06515 LOOC260_RS06530 a 5'-phospho- a 3'-phospho- a modified synthase II: 3-oxo-cis-vaccenoyl- D-glucopyranose D-ribose 5- phosphoheptulonate a 2-thiouridine 34 4-oxo-2-pentenal D-glucopyranose aspartate kinase: [DNA] [DNA] nucleobase LOOC260_RS11310 [acp] reductase: 6-phosphate phosphate in tRNA 6-phosphate ribose-phosphate synthase: LOOC260_RS07500 a [pyruvate a [pyruvate L-malate LOOC260_RS11305 glucose-6- phospho- aldehydo-D-glucuronate a 3-oxooctanoyl- pyrophosphokinase: 3-deoxy- LOOC260_RS09770 L-aspartyl- tRNA uridine-5- dehydrogenase degradation II a (3R,11Z)-3- phosphate sugar mutase: dehydrogenase [acp] D-arabino- carboxymethylaminomethyl(34) 6 6 a 2'- 527 an insertion hydroxyoctadec- isomerase: pgi LOOC260_RS01845 4-phosphate glucuronate isomerase: E2 protein] N lipoate E2 protein] N -S- a pentaglycine cross- a protein with an (S)-2- a guanine α-D-glucopyranoseLOOC260_RS08205 heptulosonate synthesis enzyme MnmG: (S)-malate deoxyribonucleoside asp O-ureido-L- sequence 3-oxooctanoyl- 11-enoyl-[acp] F6P ribose-phosphate LOOC260_RS10155 -dihydrolipoyl- acetyltransferase: acetyldihydrolipoyl- bridge of peptidoglycan LPXTG motif [DNA] halocarboxylate in 16S rRNA ITP 1-phosphate aspartate- LOOC260_RS11005 NAD-dependent 5'-triphosphate homoserine 16S rRNA element IS30 [acyl-carrier beta-hydroxyacyl- pyrophosphokinase: 7-phosphate glucuronate isomerase: L-lysine LOOC260_RS06515 L-lysine transposase: glutamine--fructose- semialdehyde malic enzyme: (guanine(527)-N(7) non-canonical protein] reductase: ACP dehydratase: UTP--glucose- LOOC260_RS06600 3-dehydroquinate tRNA uridine-5- LOOC260_RS00860 LOOC260_RS11695 6-phosphate dehydrogenase: LOOC260_RS00450 class A sortase: haloacid )-methyltransferase purine NTP LOOC260_RS11305 LOOC260_RS11320 1-phosphate PRPP synthase: carboxymethylaminomethyl(34) DNA polymerase argininosuccinate transposase: fatty acid elongation -- saturated transaminase LOOC260_RS00965 pyruvate LOOC260_RS11790 dehalogenase: RsmG: pyrophosphatase: a (3R)-3- uridylyltransferase: LOOC260_RS09765 synthesis GTPase MnmE: D-fructuronate III subunit delta: synthase: an insertionLOOC260_RS11395 3-hydroxyacyl-[acyl- (isomerizing): LOOC260_RS09440 LOOC260_RS01010 LOOC260_RS06245 hydroxyoctanoyl- aspartate- LOOC260_RS11010 acetyl-CoA class A sortase: LOOC260_RS06445 LOOC260_RS08180 an N 7 - carrier-protein] LOOC260_RS08220 3-dehydroquinate D-mannonate D-gluconate [+ 2 isozymes] sequence IS30 LOOC260_RS07985 LOOC260_RS01900 527 [+ 2 isozymes] [acp] an acetoacetyl-[acp] semialdehyde a 5-carboxymethylaminomethyl- [+ 6 isozymes] methylguanine with integrated dehydratase FabZ: UDP-α-D-glucose oxidoreductase: degradation beta-hydroxyacyl- D-glucosamine dehydrogenase: 34 IMP type I 3- 2-thiouridine in tRNA LOOC260_RS10110 in 16S rRNA transposon ACP dehydratase: LOOC260_RS11280 6-phosphate a protein with LPXT a (2R)-2- canavaninosuccinate a (2E,11Z)- dehydroquinate LOOC260_RS09585 D-gluconate a peptide with an a halide anion carboxyl end attached [DNA] LOOC260_RS11320 phosphoglucosamine D-mannonate gluconokinase: hydroxy fatty acid octadeca-2,11- dehydratase: L-aspartate 4- pyruvate fermentation to acetate IV to a pentaglycine cross- N-terminal glycine 3-hydroxyacyl-[acyl- mutase: LOOC260_RS10120 dienoyl-[acp] LOOC260_RS09780 semialdehyde mannonate bridge of peptidoglycan carrier-protein] enoyl-[acyl- LOOC260_RS07990 a 5-aminomethyl-2- lipoprotein posttranslational gluconokinase: a 3-oxoacyl-[acp] α 4-hydroxy- 34 dehydratase: dehydratase FabZ: carrier-protein] α-D-glucosamine UDP- -D-galactofuranose 3-dehydroshikimate thiouridine in tRNA pyruvate tetrahydrodipicolinate modification LOOC260_RS03715 LOOC260_RS03125 LOOC260_RS11280 1-phosphate biosynthesis D-gluconate UDP-N-acetyl- undecaprenyldiphospho- a 2'- 966 an [amino group carrier reductase FabI: a peptide with a a guanine shikimate synthase: a [prolipoprotein]- 2-dehydro-3- 6-phosphate α-D-glucosamine N-acetylmuramoyl-L- deoxyribonucleoside an alkylated DNA protein]-C-terminal-γ- acetyl-CoA a (2E)-oct- LOOC260_RS11340 bifunctional UDP-N- α [DNA] leader sequence in 16S rRNA UDP- -D-glucose dehydrogenase: LOOC260_RS06430 L-cysteine deoxy-D-gluconate alanyl-γ-D-glutamyl-meso 5'-triphosphate 16S rRNA (L-ornithyl)-L-glutamate acetyl-CoA 2-enoyl-[acp] a cis- acetylglucosamine LOOC260_RS09775 (2S,4S)-4- acetylornithine UDP-glucose 4-epimerase a 5-methylaminomethyl- prolipoprotein 2-dehydro-3- -2,6-diaminopimeloyl- (guanine(966)-N(2) carboxylase biotin vaccenoyl-[acp] diphosphorylase/ hydroxy-2,3,4,5- 34 DNA-3-methyladenine enoyl-[acyl- 3-oxoacyl-[ACP] GalE: LOOC260_RS08360 2-thiouridine in tRNA diacylglyceryl D-alanyl-D-alanine )-methyltransferase transaminase: carboxyl carrier glucosamine-1- shikimate tetrahydrodipicolinate deoxygluconokinase: acetyl-CoA formate DNA polymerase glycosylase: carrier-protein] reductase: UDP-glucose 4-epimerase: signal peptidase I: RsmD: argD protein subunit: beta-ketoacyl-[acyl- transferase: LOOC260_RS10070 III subunit delta: LOOC260_RS00695 an [amino group carrier phosphate N- phosphate undecaprenyldiphospho- LOOC260_RS10980 reductase FabI: carrier-protein] LOOC260_RS11305 LOOC260_RS08695 LOOC260_RS08230 2 LOOC260_RS06475 γ LOOC260_RS11315 acetyltransferase α shikimate kinase: LOOC260_RS06445 an N - protein]-C-terminal- -(L- LOOC260_RS11340 UDP- -D-galactose KDGP acetyltransferase: muramoylpentapeptide beta-N- synthase II: LOOC260_RS09745 a 5-methylaminomethyl- [+ 6 isozymes] 966 glutamate 5-semialdehyde- [+ 6 isozymes] GlmU: prolipoprotein acetylglucosaminyltransferase: a DNA containing methylguanine cis-vaccenate LOOC260_RS11310 a (3R)-3- UDP-galactopyranose dipicolinate 2-(S-geranyl) LOOC260_RS08040 an alkylated 2-yl)-L-glutamate malonyl-CoA a 2,3,4-saturated LOOC260_RS01840 shikimate 3- diacylglyceryl LOOC260_RS06700 an apurinic/ in 16S rRNA an octanoyl-[acp] hydroxyacyl-[acyl- 34 nucleobase fatty acyl-[acp] α mutase: LOOC260_RS03295 4-hydroxyphenylpyruvate thiouridine in tRNA transferase: a leader sequence a peptide carrier protein] N-acetyl- -D- phosphate bifunctional 2-keto- acetyl phosphate apyrimidinic site glucosamine UDP-Galf biosynthesis LOOC260_RS09065 [DNA] beta-ketoacyl-[acyl- 3-hydroxyacyl-[acyl- 3-phosphoshikimate 1- 4-hydroxyglutarate lipid II (meso UDP 1-phosphate a [prolipoprotein]- carrier-protein] carrier-protein] carboxyvinyltransferase: aldolase/2- acetate kinase: mevalonate degradation diaminopimelate containing) tyr S-1,2-diacyl-sn- synthase II: dehydratase FabZ: bifunctional UDP-N- LOOC260_RS09755 a 5-methylaminomethyl- keto-3-deoxy-6- LOOC260_RS07250 LOOC260_RS11280 aspartate 2-(Se-phospho) glyceryl-L-cysteine LOOC260_RS11310 acetylglucosamine 5-enolpyruvoyl- phosphogluconate 1518 38- 34 (R)-mevalonate a nascent peptidoglycan an [HPr]- phosphoenol adenine / a uridine (3R,5S)-3- beta-hydroxyacyl- shikimate 3- aminotransferase: selenouridine in tRNA acetate a peptide with a diphosphorylase/ aldolase: with (L-alanyl-γ-D-glutamyl- 1519 hydroxy-1- a 3-oxodecanoyl- LOOC260_RS09260 signal peptidase II: gly L-histidine pyruvate adenine in 16S rRNA 40 in tRNA AMP ACP dehydratase: glucosamine-1- phosphate LOOC260_RS10065 hydroxymethylglutaryl- meso-2,6-diaminopimeloyl- penultimate glycine 16S rRNA RluA family pyrroline-5- [acp] 3-(4- [+ 3 isozymes] LOOC260_RS05290 LOOC260_RS11320 phosphate N- chorismate synthase: CoA reductase, D-alanine) tetrapeptide (adenine(1518)-N(6)/ pseudouridine carboxylate 3-oxodecanoyl- hydroxyphenyl) bifunctional 2-keto- pyrroline-5- a trans-2- acetyltransferase LOOC260_RS09760 a 5-methylaminomethyl- an (S-diacyl- degradative: phosphoenolpyruvate- adenine(1519)-N(6))- synthase: 5'-nucleotidase: a 2,3,4-saturated enoyl-[acyl-carrier- pyruvate a lipoprotein 4-hydroxyglutarate [acyl-carrier 2-selenouridine 34 -protein carboxypeptidase: carboxylate reductase: LOOC260_RS07240 protein] reductase: enoyl-[acyl- GlmU: sn-glyceryl) signal peptide aldolase/2- LOOC260_RS01750 L,D-transpeptidase: dimethyltransferase LOOC260_RS06775 protein] reductase: fatty acyl-[acp] in tRNA phosphotransferase: LOOC260_RS05185 LOOC260_RS02075 LOOC260_RS11340 carrier protein] LOOC260_RS01840 chorismate -L-cysteinyl- keto-3-deoxy-6- LOOC260_RS06125 RsmA: [+ 4 isozymes] LOOC260_RS11305 HMG-CoA LOOC260_RS03420 38- UDP-N-acetyl- [apolipoprotein] LOOC260_RS01790 a pseudouridine Hyp adenosine a (3R)-3- phosphogluconate N 6 -dimethyladenine 1518 α-D-glucosamine 40 in tRNA aldolase: 6 1519 hydroxydecanoyl- enoyl-[acyl- a nascent peptidoglycan an [HPr protein]- a peptide with a /N -dimethyladenine LOOC260_RS03755 γ π an amino acid [acp] carrier-protein] a peptide with (L-alanyl- -D-glutamyl- D-ala N -phospho- pyruvate C-terminal glycine in 16S rRNA beta-hydroxyacyl- an N-acyl-(S- reductase FabI: meso-2,6-diaminopimeloyl- L-histidine ACP dehydratase: diacyl-sn-glyceryl) D-glyceraldehyde LOOC260_RS11340 pyruvate acetyl-CoA glycine) tetrapeptide LOOC260_RS11320 -L-cysteinyl- 3-phosphate acetoacetate [lipoprotein] 3-hydroxyacyl-[acyl- Amino Acid Biosynthesis 1402 a [lipoyl-carrier 3-phenyl-2- an unsulfurated a cytidine carrier-protein] tyr cys a tRNA precursor a [protein] Ser/Thr protein]-N 6 -[(R) oxopropanoate [sulfur carrier] in 16S rRNA IMP dehydratase FabZ: superpathway of L- HPr kinase/ 16S rRNA -dihydrolipoyl]- L-lysine biosynthesis II LOOC260_RS11280 isoleucine biosynthesis I L-histidine biosynthesis superpathway of L-methionine biosynthesis (transsulfuration) L-arginine biosynthesis I (via L-ornithine) superpathway of L-homoserine and L-methionine biosynthesis L-arginine biosynthesis II (acetyl cycle) phosphorylase: (cytidine(1402)-2'-O) L-lysine biotin-carboxyl carrier protein assembly tRNA processing Detoxification dihydrolipoyl aromatic amino acid LOOC260_RS08235 -methyltransferase: 5'-nucleotidase: a (2E)-dec- cysteine desulfurase: ribonuclease Z: dehydrogenase: a [biotin carboxyl- oxaloacetate PRPP oxaloacetate N-acetylglutamyl- aminotransferase: serine/threonine LOOC260_RS08370 LOOC260_RS07240 2-enoyl-[acp] asp glu asp a polycistronic LOOC260_RS07565 LOOC260_RS06370 a 2'-O- LOOC260_RS06515 carrier protein]-L-lysine aspartate phosphate arsenate LOOC260_RS09360 a [lipoyl-carrier N-acetyl-gamma- arsenate arsenate detoxification V [+ 2 isozymes] protein kinase: methylcytidine 1402 enoyl-[acyl- aminotransferase: ATP aspartate kinase: tRNA precursor detoxification phenylmercury acetate degradation protein]-N 6 - biotin--[acetyl-CoA- aspartate aminotransferase: bifunctional glutamate glutamyl-phosphate detoxification [+ 2 isozymes] LOOC260_RS04985 inosine carrier-protein] LOOC260_RS09260 phosphoribosyltransferase: LOOC260_RS07500 aspartate kinase: III (thioredoxin) in 16S rRNA lipoyl-L-lysine carboxylase] ligase: LOOC260_RS09260 N-acetyltransferase/ reductase: II (glutaredoxin) a [protein] (L-serine/L- reductase FabI: LOOC260_RS10455 L-aspartyl- LOOC260_RS07500 acetylglutamate kinase: mercuriphenyl arsenate a single-stranded asp LOOC260_RS00150 3-(4- mature tRNA threonine) phosphate LOOC260_RS11345 amino-acid bifunctional glutamateLOOC260_RS00160 arsenate acetate type I glyceraldehyde- ala a sulfurated oligoribonucleotide LOOC260_RS11340 ATP 4-phosphate asp arsenate hydroxyphenyl) phe biotin--[acetyl-CoA- acetyltransferase ArgJ: N-acetyltransferase/ arsenate reductase 3-phosphate [sulfur carrier] phosphoribosyltransferase L-aspartyl-4-phosphate a tRNA precursor a tRNA precursor arsenate reductase: pyruvate a decanoyl-[acp] carboxylase] ligase: aspartate kinase: aspartate- LOOC260_RS00155 amino-acid (thioredoxin): dehydrogenase: regulatory subunit: with a 5' with a 5' LOOC260_RS06585 LOOC260_RS09430 LOOC260_RS07500 semialdehyde aspartate kinase: acetyltransferase ArgJ: LOOC260_RS11140 LOOC260_RS08135 LOOC260_RS10460 LOOC260_RS07500 N-acetyl-L- extension and extension and a arsenite 1-arseno-3- beta-ketoacyl-[acyl- a [biotin carboxyl- dehydrogenase: aspartate-semialdehyde LOOC260_RS00155 N-acetyl-L-glutamate arsenate reductase quinoxaline-2- (1S,2R)-1- lysine within salicin 6- UDP-N-acetyl- glutamate a long 3' trailer 2+ carrier protein]-N L-aspartyl- 1-(5-phospho- LOOC260_RS00965 dehydrogenase: glu N-acetyl-L-glutamate short 3' extension (thioredoxin): acetate benzene Hg phosphoglycerate aryl-carrier protein C-(indol-3- (R)-lipoate D-alanyl-D-alanine α-D-glucosamine asp carrier-protein] 5-semialdehyde ribonuclease P arsenical pump- carboxyl adenylate ser gcv protein H phosphate 6 4-phosphate β-D-ribosyl)-ATP LOOC260_RS00965 UDP-N- synthase II: -biotinyl-L-lysine aspartate- L-aspartyl-4-phosphate acetylglutamate kinase: acetylornithine LOOC260_RS09785 driving ATPase: yl)glycerol D-alanyl-D-alanine aspartate racemase: protein component: mercury(II) reductase: acetylglucosamine LOOC260_RS11310 semialdehyde LOOC260_RS00160 aspartate-semialdehyde transaminase: arsenite LOOC260_RS11125 3-phosphate dipeptidase: LOOC260_RS10530 aspartate- LOOC260_RS11025 LOOC260_RS09020 lipoate--protein ligase: aryl-phospho-beta- 2-epimerase (non- a 3- dehydrogenase: dehydrogenase: argD LOOC260_RS00610 semialdehyde aspartate-semialdehyde N-acetylglutamyl- a tRNA a tRNA precursor arsenical pump- arsenical pump- 1-arseno-3- acyl carrier protein: LOOC260_RS02965 D-glucosidase: aspartate racemase: oxododecanoyl- LOOC260_RS09585 LOOC260_RS09585 tryptophan synthase: hydrolyzing): a [biotin carboxyl- 0 LOOC260_RS10975 dehydrogenase: 1-(5-phospho-β- dehydrogenase: phosphate precursor with with a short driving ATPase: driving ATPase: Hg phosphoglycerate LOOC260_RS05030 [+ 2 isozymes] LOOC260_RS09295 LOOC260_RS03175 [acp] gln LOOC260_RS10340 D-ala carrier-protein dimer]- LOOC260_RS00965 D-ribosyl)-AMP L-aspartate 4- LOOC260_RS00965 a 5' extension 3' extension LOOC260_RS11125 LOOC260_RS09145 UDP-N-acetyl-α- D-aspartate 3-oxododecanoyl- 6 N-acetyl-gamma- L-aspartate 4-semialdehyde LOOC260_RS10345 N -biotinyl-L-lysine semialdehyde aspartate-semialdehyde D-mannosamine [acyl-carrier aspartate- glutamyl-phosphate arsenical pump- a [glycine-cleavage β-D-glucose acetyl-CoA carbamoyl- ribonuclease P arsenite a quinoxaline-2- salicyl alcohol protein] reductase: semialdehyde 4-hydroxy- dehydrogenase: homoserine driving ATPase: D-glyceraldehyde complex H protein] 6-phosphate acetyl-CoA reductase: phosphate synthase: protein component: carboxyl-[aryl- carboxylase dehydrogenase: LOOC260_RS09585 dehydrogenase: N-acetyl-L-ornithine AMP 3-phosphate trp 6 LOOC260_RS11305 carboxylase biotin 1-(5-phospho-β-D-ribosyl)- tetrahydrodipicolinate LOOC260_RS00150 bifunctional glutamate LOOC260_RS09145 N -lipoyl-L-lysine a (3R)-3- subunit beta: LOOC260_RS00140 LOOC260_RS11025 carrier protein] carboxylase subunit: LOOC260_RS09585 5-[(5-phosphoribosylamino) synthase: N-acetyl-L- LOOC260_RS09460 LOOC260_RS11330 L-aspartate 4-semialdehyde LOOC260_RS00145 N-acetyltransferase/ hydroxydodecanoyl- LOOC260_RS06430 glutamate 5- arsenite LOOC260_RS11325 L-aspartate 4- methylideneamino]imidazole- [+ 2 isozymes] amino-acid [acp] [+ 3 isozymes] (2S,4S)-4- semialdehyde L-homoserine an uncharged semialdehyde 4-carboxamide acetyltransferase ArgJ: 37 beta-hydroxyacyl- a [carboxyl-carrier homoserine a nascent peptidoglycan (R)-mevalonate adenine hydroxy-2,3,4,5- acetylornithine carbamoyl phosphate L-ornithine tRNA an acyl-[acyl- (S)-2- canavaninosuccinate an unfolded protein dimer]-N 6 - homoserine 1-(5-phosphoribosyl)-5- dehydrogenase: LOOC260_RS00155 (meso-DAP containing) glu in tRNA val ACP dehydratase: tetrahydrodipicolinate transaminase: carrier protein] aminobutanoate diphosphate 1 [(5- phosphoribosylamino) tRNA1(Val) protein LOOC260_RS11320 carboxybiotinyl-L-lysine dehydrogenase: 4-hydroxy- LOOC260_RS09460 hydrogencarbonate argD homoserine O- Fatty Acid and Lipid Degradation diphosphomevalonate methylideneamino]imidazole- succinyltransferase: Aromatic Compound endolytic (adenine(37)-N6)- chaperonin GroEL: 3-hydroxyacyl-[acyl- LOOC260_RS09460 tetrahydrodipicolinate argininosuccinate decarboxylase: 4- carboxamide isomerase: L-homoserine carbamoyl- N-acetyl-L- LOOC260_RS06805 Degradation transglycosylase MltG: phosphate glutamate-- methyltransferase: LOOC260_RS08325 reductase: 6 37 oleate β-oxidation lyase: LOOC260_RS05155 carrier-protein] L-homoserine LOOC260_RS10435 phosphate synthase: ornithine N -L-threonylcarbamoyladenosine glycerol degradation I LOOC260_RS05870 LOOC260_RS05495 cys LOOC260_RS04475 acyltransferase PlsX: cysteine ligase: LOOC260_RS08175 an N 6 - dehydratase FabZ: LOOC260_RS00140 -modified tRNA biosynthesis protocatechuate phosphoribulosylformimino- ornithine LOOC260_RS05025 LOOC260_RS09655 IPP methyladenine 37 a protein LOOC260_RS11280 (S)-2,3,4,5- homoserine O- LOOC260_RS00145 degradation II (ortho- oleate homoserine kinase: O-succinyl-L-homoserine carbamoyltransferase: val AICAR-phosphate tetrahydrodipicolinate glycerol a mature peptidoglycan a nascent peptidoglycan in tRNA a (2E)-dodec- succinyltransferase: [+ 2 isozymes] LOOC260_RS00170 cleavage pathway) 1 fatty acid biosynthesis LOOC260_RS09465 ATP acyl-CoA synthetase: with (L-alanyl-γ-D-glutamyl- (meso-DAP containing) γ-L-glutamyl-(S)- L-canavanine fumarate 2-enoyl-[acp] 2,3,4,5- LOOC260_RS06805 L-tryptophan biosynthesis thr initiation (bacteria and plants) carbamoyl ornithine protocatechuate LOOC260_RS01720 meso-2,6-diaminopimeloyl- with GlcNAc terminus acyl-carrier protein an acyl phosphate O-phospho- imidazole glycerol tetrahydropyridine- cys L-ornithine cystathionine 2-aminobutanoate enoyl-[acyl- phosphate carbamoyltransferase: glycerol D-alanine) tetrapeptide L-homoserine phosphate synthase: 2,6-dicarboxylate N- gamma-synthase: acyl-CoA synthetase: carrier-protein] acetyl-CoA LOOC260_RS10430 O-succinyl-L-homoserine LOOC260_RS10780 chorismate threonylcarbamoyl- LOOC260_RS01695 acetyltransferase: LOOC260_RS01810 3-carboxy-cis glycerol kinase: reductase FabI: acetyl-CoA carboxylase LOOC260_RS10440 AMP synthase: 4 threonine synthase: LOOC260_RS07340 ornithine an O - 1498 ,cis-muconate oleoyl-CoA LOOC260_RS05125 a pentaglycine cross- a [protein]- arbutin 6- a uracil LOOC260_RS11340 subunit beta: LOOC260_RS09455 carbamoyltransferase: anthranilate synthase: LOOC260_RS07790 a protein with a ribonucleoside a single acetoacetyl-CoA methylthymine phosphate in 16S rRNA asp LOOC260_RS11330 D-erythro-1- L-2-acetamido-6- cystathionine LOOC260_RS10370 glycerol kinase: bridge of peptidoglycan NPXTN motif L-cysteine triphosphate stranded DNA LOOC260_RS00170 L-cystathionine acyl-CoA in DNA 16S rRNA a dodecanoyl-[acp] AICAR (imidazol-4- LOOC260_RS10185 3-hydroxybutyryl- [+ 3 isozymes] thr oxoheptanedioate gamma-synthase: (L-threonylcarbamoyl) (uracil(1498)-N(3))- aspartate 4- ornithine anthranilate dehydrogenase: CoA dehydrogenase: malonyl-CoA yl)-glycerol LOOC260_RS01810 L-citrulline adenylate (2-carboxy- sn-glycerol aryl-phospho-beta- decarboxylase: carbamoyltransferase: LOOC260_RS10630 SrtB family sortase: methylated-DNA-- LOOC260_RS09335 methyltransferase: 3-phosphate L-cystathione β-lyase: 2,5-dihydro- 3-phosphate DNA primase: D-glucosidase: LOOC260_RS10540 ACP S- bifunctional threonine LOOC260_RS10780 anthranilate tRNA (adenosine(37)-N6)- (2E,9Z)- LOOC260_RS00280 [protein]-cysteine S- (S)-3- 3 LOOC260_RS05720 beta-ketoacyl-[acyl- imidazoleglycerol- LOOC260_RS01810 argininosuccinate 5-oxofuran- LOOC260_RS05620 LOOC260_RS09295 an N - ammonia-lyase/L- phosphoribosyltransferase: threonylcarbamoyltransferase methyltransferase: hydroxybutanoyl- 1498 carrier-protein] malonyltransferase: phosphate N-acetyl-L,L-2,6- L-cystathionine octadecenoyl-CoA methyluracil ala serine ammonia- synthase: LOOC260_RS10360 complex ATPase subunit type 2-yl)-acetate LOOC260_RS00615 CoA synthase II: LOOC260_RS11300 dehydratase carboxymuconolactone a protein with NPXT in 16S rRNA diaminopimelate asp L-citrulline LOOC260_RS08180 N-(5- 1 TsaE: LOOC260_RS08035 enoyl-CoA hydratase: β-D-glucose LOOC260_RS11310 laurate lyase TdcB: 2-aminoprop-2-enoate a peptide with an N- ssDNA/pppN(pN) HisB: hisB N-acetyl- L-homocysteine decarboxylase: LOOC260_RS09865 carboxyl end attached 6-phosphate hydroquinone a malonyl-[acp] LOOC260_RS09495 3-(imidazol-4- L-cystathione β-lyase: phosphoribosyl) tRNA (adenosine(37)-N6)- DHAP terminal L-asparagine a [protein]-S- hybrid acyl-CoA synthetase: diaminopimelate L-arginino-succinate LOOC260_RS08745 to a pentaglycine cross- a thymine in DNA n -1 (2Z)-2-aminobut- yl)-2-oxopropyl LOOC260_RS01810 -anthranilate threonylcarbamoyltransferase (4,5-dihydro- (S)-3-hydroxy-(9Z) methyl-L-cysteine a 3-oxotetradecanoyl- LOOC260_RS01720 deacetylase: argininosuccinate 5-methyltetrahydropteroyltriglutamate- bridge of peptidoglycan ketoacyl-ACP synthase 2-enoate phosphate argininosuccinate phosphoribosylanthranilate complex: LOOC260_RS08345 -octadecenoyl-CoA synthase: - homocysteine S-methyltransferase: methionine synthase: 5-oxofuran- [acp] acyl-CoA synthetase: III: LOOC260_RS11290 histidinol-phosphate LOOC260_RS07335 lyase: isomerase: LOOC260_RS10625 LOOC260_RS08355 2-yl)-acetate 6 2-aminoprop-2-enoate LOOC260_RS08180 LOOC260_RS00480 UDP-N-acetyl- decaprenyl-diphospho-N- an O - 34 3-oxotetradecanoyl- LOOC260_RS01695 ketoacyl-ACP synthase transaminase: L-homocysteine 2-iminopropanoate LOOC260_RS08175 LOOC260_RS10350 an N 6 -L- a [protein]- an all-trans a cytidine a protein L,L- α nicotinate PRPP a nucleoside 5-methyltetrahydropteroyltriglutamate- 37 -D-glucosamine acetylmuramoyl-pentapeptide methylguanine with incorrect [acyl-carrier III: LOOC260_RS02120 LOOC260_RS10415 diaminopimelate tryptophan synthase threonylcarbamoyladenine L-cysteine -retinyl ester in tRNA triphosphate lauroyl-CoA L-arginino- 3-oxo-(9Z)- in DNA protein] reductase: 5-methyltetrahydropteroyltriglutamate- - homocysteine S-methyltransferase: arg subunit beta: in tRNA tRNA (cytidine(34)-2'- disulfide bonds nucleoside 2-iminobutanoate L-histidinol diaminopimelate succinate LOOC260_RS10625 octadecenoyl-CoA dithiol-disulfide LOOC260_RS11305 an acetoacetyl-[acp] - homocysteine S-methyltransferase: methionine synthase: LOOC260_RS10345 3-oxoadipate undecaprenyldiphospho- nicotinate O)-methyltransferase: triphosphate phosphate epimerase: argininosuccinate methylated-DNA-- carboxylesterase: isomerase: a (3R)-3- LOOC260_RS00480 LOOC260_RS10625 1-(2- muramoylpentapeptide beta-N- phosphoribosyltransferase: LOOC260_RS06750 hydrolase: LOOC260_RS06655 2-iminopropanoate lyase: met pyruvate [protein]-cysteine S- LOOC260_RS08065 a 2'-O- LOOC260_RS06790 hydroxytetradecanoyl- histidinol-phosphatase: 5-methyltetrahydropteroyltriglutamate- carboxyphenylamino) acetylglucosaminyltransferase: LOOC260_RS02090 a protein LOOC260_RS03590 LOOC260_RS08175 methyltransferase: methylcytidine 34 a nucleoside [acp] LOOC260_RS10465 meso- - homocysteine S-methyltransferase: -1-deoxy-D-ribulose queuosine biosynthesis I (de novo) LOOC260_RS06700 with correct superpathway of L- LOOC260_RS00615 in tRNA diphosphate beta-hydroxyacyl- 2-oxobutanoate diaminopimelate 5-phosphate (7Z)-hexadecenoyl-CoA disulfide bonds LOOC260_RS10625 threonine biosynthesis indole-3-glycerol ACP dehydratase: histidinol arg decaprenyl-pyrophosphoryl- all-trans-retinol a fatty acid diaminopimelate preQ acyl-CoA UDP NaMN LOOC260_RS11320 acyl-CoA hydrolysis acetolactate phosphate 0 decarboxylase: pyruvate (N-acetylglucosamine)-N- a [protein]-S- synthase AlsS: histidinol met oxaloacetate L-cysteine biosynthesis I L-glutamine synthase TrpC: dehydrogenase: a guanine in DNA 3-hydroxyacyl-[acyl- LOOC260_RS05120 acetylmuramyl-(pentapeptide) methyl-L-cysteine a 2,3,4-saturated LOOC260_RS04135 dehydrogenase: aspartate biosynthesis I LOOC260_RS10355 LOOC260_RS10630 carrier-protein] (1S,2R)-1- fatty acyl CoA LOOC260_RS10450 aminotransferase: preQ (2E,7Z)- dehydratase FabZ: acyl-CoA thioesterase: (S)-2-aceto-2- lys 1 LOOC260_RS09260 ser C-(indol-3- 10 hydroxybutanoate glu hexadecenoyl-CoA an L-methionyl- an N - a [protein]- a DNA methyl D-threo-7,8- all-trans- 5-dehydro-4-deoxy- LOOC260_RS11280 LOOC260_RS11715 histidinal yl)glycerol tRNA-guanine(34) [DNA] an aromatic glycine biosynthesis II asp serine O-acetyltransferase: type I glutamate-- Met formyltetrahydrofolate L-cysteine phosphotriester dihydroneopterin retinyl palmitate D-glucuronate acyl-CoA thioesterase: 3-phosphate enoyl-CoA hydratase: [initiator tRNA ] 5-dehydro-4-deoxy- amino acid a (2E)-tetradec- L-tyrosine biosynthesis I LOOC260_RS01815 ammonia ligase: transglycosylase: DNA polymerase histidinol tryptophan synthase: LOOC260_RS09865 aromatic amino acid 2-enoyl-[acp] a 2,3,4-saturatedLOOC260_RS03585 a [glycine-cleavage LOOC260_RS07435 D-glucuronate III subunit delta: L-proline biosynthesis dehydrogenase: aspartate kinase: O-acetyl-L-serine LOOC260_RS04545 methylated-DNA-- dihydroneopterin aminotransferase: complex H protein] N 6 - LOOC260_RS10340 a 7-aminomethyl-7- carboxylesterase: isomerase: LOOC260_RS06445 enoyl-[acyl- fatty acid (R)-2,3-dihydroxy- I (from L-glutamate) LOOC260_RS10450 chorismate LOOC260_RS07500 gln (S)-3-hydroxy-(7Z) methionyl-tRNA LOOC260_RS09360 LOOC260_RS10345 deazaguanosine 34 [protein]-cysteine S- aldolase: LOOC260_RS10085 phosphatidylglycerol 3-methylpentanoate aminomethyldihydrolipoyl- glycine cleavage -hexadecenoyl-CoA formyltransferase: LOOC260_RS08065 [+ 4 isozymes] carrier-protein] glycine cleavage O-acetylhomoserine methyltransferase: LOOC260_RS06265 3-deoxy-D-glycero- [+ 2 isozymes] biosynthesis II (non-plastidic) L-lysine ser in tRNA LOOC260_RS04970 a nucleoside 5'- an aromatic reductase FabI: glu his system protein H: system protein H: L-aspartyl- aminocarboxypropyltransferase/ indole LOOC260_RS00615 glycine biosynthesis I S-adenosylmethionine:tRNA 2,5-hexodiulosonate monophosphate 2-oxo-acid LOOC260_RS11340 prephenate LOOC260_RS07685 4-phosphate cysteine synthase: DHAP glutamate 5-kinase: LOOC260_RS07685 ribosyltransferase-isomerase: 6-(hydroxymethyl) gly LOOC260_RS06800 an N-formyl- glycolaldehyde all-trans-retinol palmitate NAD(P)H-dependent (S)-3-methyl-2- LOOC260_RS10000 aspartate- tryptophan synthase: LOOC260_RS07440 3-oxo-(7Z)- a tetrahydrofolate a [protein]-S- -7,8-dihydropterin a myristoyl-[acp] γ-L-glutamyl prephenate O-acetylhomoserine L-methionyl- [DNA] glycerol-3-phosphate oxopentanoate semialdehyde ser LOOC260_RS10340 an epoxyqueuosine 34 hexadecenoyl-CoA methyl-L-cysteine dehydrogenase/ a [glycine- [initiator tRNA met ] 5-phosphate a [glycine- dehydrogenase: aminocarboxypropyltransferase/ LOOC260_RS10345 beta-ketoacyl-[acyl- dehydrogenase: arogenate cleavage complex serine in tRNA glutamate-5- L-homocysteine biosynthesis cleavage complex LOOC260_RS00965 cysteine synthase: carrier-protein] LOOC260_RS08225 dehydrogenase H protein] N 6 - hydroxymethyltransferase: glyA sn-glycerol semialdehyde H protein] N 6 - LOOC260_RS10850 UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N methyl (indol- (-)-methyl a negatively synthase II: family protein: dihydrolipoyl- aspartate- gly DHAP histidinol 3-phosphate lipoyl-L-lysine trp (5Z)-tetradecenoyl-CoA -acetylmuramoyl-L-alanyl-γ- DL-allothreonine supercoiled DNA LOOC260_RS11310 dehydrogenase: L-homoserine LOOC260_RS09750 L-lysine semialdehyde 3-yl)acetate jasmonate ile cys a queuosine 34 DNA topoisomerase NAD(P)H-dependent glycerol-3-phosphate LOOC260_RS09995 3-(4- dehydrogenase: D-glutamyl-L-lysyl- D-alanine histidinol a 3-oxohexadecanoyl- in tRNA acyl-CoA IV subunit A: glycerol-3-phosphate dehydrogenase: acyltransferase: L-glutamate-5- homoserine O- hydroxyphenyl) L-phenylalanine LOOC260_RS09585 undecaprenyldiphospho- [acp] dehydrogenase: carboxylesterase: carboxylesterase: LOOC260_RS05405 dehydrogenase: LOOC260_RS05415 acetyltransferase: pyruvate glycine cleavage biosynthesis I muramoylpentapeptide beta-N- LOOC260_RS10450 semialdehyde L-aspartate 4- LOOC260_RS10630 serine LOOC260_RS08065 LOOC260_RS08065 (R)-3-hydroxypalmitoyl- a 1-acyl-sn aspartate system protein H: acetylglucosaminyltransferase: [+ 2 isozymes] LOOC260_RS08225 LOOC260_RS06805 semialdehyde hydroxymethyltransferase: glyA -glycerol 3- LOOC260_RS07685 chorismate alanine racemization (2E,5Z)- a relaxed DNA sn-glycerol his [acp] reductase: aminotransferase: Pentose Phosphate Pathways LOOC260_RS06700 phosphate O-acetyl-L- homoserine superpathway of L-asparagine biosynthesis tetradecenoyl-CoA 3-phosphate LOOC260_RS11305 hydrogen sulfide LOOC260_RS09260 dihydrolipoyl a (3R)-3- 1-acyl-sn-glycerol- homoserine dehydrogenase: ditrans,octacis-undecaprenyldiphospho- (indol-3-yl)acetate MeOH (-)-jasmonate MeOH (S)-1-pyrroline- [+ 3 isozymes] dehydrogenase: UDP hydroxyhexadecanoyl- 3-phosphate LOOC260_RS09460 ala pentose phosphate pathway enoyl-CoA hydratase: N-acetyl-(N-acetylglucosaminyl)muramoyl- acetaldehyde gly 5-carboxylate LOOC260_RS06515 prephenate [acp] acyltransferase: O-acetylhomoserine tyr asp alanine racemase: LOOC260_RS09865 L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine pyrroline-5- D-glucopyranose beta-hydroxyacyl- LOOC260_RS05875 aminocarboxypropyltransferase/ L-homoserine LOOC260_RS01935 (3E,5Z)-tetradeca- carboxylate reductase: 6-phosphate ACP dehydratase: 1-acyl-sn-glycerol- cysteine synthase: D-ala 3,5-dienoyl-CoA (S)-3-hydroxy-(5Z) LOOC260_RS02075 L-glutamate asparagine synthase asparagine synthase UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N-acetylmuramoyl-L- p-nitrophenyl-α-D- a (1->4)- a [protein]-L- a [protein]- LOOC260_RS11320 3-phosphate LOOC260_RS06800 homoserine kinase: glucose-6-phosphate -tetradecenoyl-CoA γ methanethiol O-succinyl-L- biosynthesis III L-alanine 3-phenyl-2- (glutamine-hydrolyzing) (glutamine-hydrolyzing) acyl-CoA thioesterase: alanyl- -D-glutamyl-L-lysyl- D-alanyl-D-alanine galactopyranoside α-D-glucan proline (ω = 180) ser L-histidine 3-hydroxyacyl-[acyl- acyltransferase: LOOC260_RS09465 dehydrogenase: homoserine pro O-acetylhomoserine biosynthesis III oxopropanoate : LOOC260_RS10985 : LOOC260_RS10985 LOOC260_RS11715 peptidylprolyl bifunctional threonine carrier-protein] LOOC260_RS02290 LOOC260_RS10195 undecaprenyldiphospho- histidine kinase: aminocarboxypropyltransferase/ 2-oxoglutarate aspartate O-phospho- 6-phospho acyl-CoA thioesterase: alpha-glucosidase: isomerase: ammonia-lyase/L-serine dehydratase FabZ: a 1,2-diacyl- muramoylpentapeptide beta-N- cystathionine alpha-galactosidase: LOOC260_RS07575 cysteine synthase: NADP-specific cys aminotransferase: L-homoserine D-glucono- LOOC260_RS03585 3-oxo-(5Z)- LOOC260_RS09330 LOOC260_RS08560 ammonia-lyase TdcB: LOOC260_RS11280 sn-glycerol acetylglucosaminyltransferase: gamma-synthase: LOOC260_RS06045 LOOC260_RS10850 glutamate LOOC260_RS09260 asn asn (3E,5Z)- tetradecenoyl-CoA [+ 2 isozymes] LOOC260_RS09495 a [protein]- 3-phosphate cysteine desulfurase: 1,5-lactone LOOC260_RS06700 [+ 3 isozymes] a [protein]-L- a (2E)-hexadec- dehydrogenase: threonine synthase: LOOC260_RS01810 N-phospho- phosphatidate LOOC260_RS06625 [+ 3 isozymes] tetradecadienoate ω pyruvate LOOC260_RS00380 LOOC260_RS09455 proline ( = 0) L-histidine 2-enoyl-[acp] cytidylyltransferase: [+ 2 isozymes] a (1->4)- L-homocysteine ditrans,octacis-undecaprenyldiphospho-N- UDP D-galactopyranose 4-nitrophenol D-glucopyranose enoyl-[acyl- LOOC260_RS05830 glu ala phe succinate α-D-glucan thr D-gluconate (3Z)-dodec- acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L- met carrier-protein] a CDP- 6-phosphate 3-enoyl-CoA alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine reductase FabI: diacylglycerol 6-phosphogluconate LOOC260_RS11340 CDP-diacylglycerol-- dehydrogenase a [ThiI sulfur- a 2,3,4-saturated DNA combined with guanosine 2251 3-octaprenyl-4- glycerol-3-phosphate 3- a uracil in tRNA carrier protein]-S- 1,2-diacyl-sn- exogenous DNA to form aminomalonate thr a palmitoyl-[acp] (decarboxylating): (2E)-dodec- in 23S rRNA hydroxybenzoate phosphatidyltransferase: sulfanyl-L-cysteine glycerol 3-phosphate CTP a recombinational junction 23S rRNA 3-octaprenyl-4- LOOC260_RS10050 2-enoyl-CoA Holliday junction aspartate 4- LOOC260_RS07480 Cofactor, Carrier, and Vitamin Biosynthesis (guanosine(2251)-2'- L-threonine 3- phosphogluconate resolvase RuvX: hydroxybenzoate decarboxylase: 1-(3-sn- crotonase: tRNA 4-thiouridine(8) dehydrogenase: phosphatidate LOOC260_RS07400 O)-methyltransferase carboxy-lyase: LOOC260_RS10540 phosphatidyl) dehydrogenase LOOC260_RS09865 LOOC260_RS09475 [2Fe-2S] iron-sulfur cluster biosynthesis synthase ThiI: cytidylyltransferase: RlmB: LOOC260_RS03105 -sn-glycerol thiamine phosphate formation from thiamine diphosphate salvage II folate transformations III (E. coli) lipoate biosynthesis coenzyme A biosynthesis phosphopantothenate biosynthesis I NAD salvage (NADP(+)-dependent, Holliday junction (S)-3- LOOC260_RS07560 LOOC260_RS05830 LOOC260_RS02220 2-octaprenylphenol gly aminoacetone palmitate 3-phosphate pyrithiamine and oxythiamine (yeast) and incorporation II I (prokaryotic) thiamine diphosphate pathway III (to decarboxylating): resolution of recombinationalresolvase RecU: recU 2-O- hydroxydodecanoyl-CoA 2251 phosphatidylglycerophosphatase L-cysteine desulfurase 4-amino-2-methyl-5- 3-methyl-2- a 5,10- biosynthesis III LOOC260_RS10200 junction formation methylguanosine acyl-CoA synthetase: a tetrahydrofolate (R)-4'- nicotinamide riboside) A: LOOC260_RS07215 pyrithiamine pyrimidinemethanol octanoate oxobutanoate methylenetetrahydrofolate (Staphylococcus) D-ribulose a [ThiI sulfur-carrier a 4-thiouracil in tRNA a CDP-2,3,4-saturated- of two intact strands in 23S rRNA LOOC260_RS01720 phosphopantothenate 2-(2-carboxy-4- NADP + phosphatidylglycerophosphatase cysteine desulfurase: bifunctional lipoate--protein ligase: bifunctional 5-phosphate protein]-L-cysteine diacylglycerol acyl-CoA synthetase: thiaminase II: methylthiazol-5- A: LOOC260_RS10495 LOOC260_RS06625 hydroxymethylpyrimidine LOOC260_RS09695 phosphopantothenoylcysteine HMP-PP LOOC260_RS01695 an L-1- LOOC260_RS10710 kinase/ yl)ethyl phosphate 3-oxododecanoyl-CoA [+ 2 isozymes] methionine synthase: a [lipoyl-carrier [+protein] 2 isozymes] decarboxylase/ ribulose-phosphate ribose-5-phosphate phosphatidyl- NAD + 967 4-amino-2-methyl-5- phosphomethylpyrimidine LOOC260_RS10625 6 phosphopantothenate-- 3-epimerase: isomerase RpiA: UDP-N-acetyl-α-D-muramoyl- 37 a cytosine a (2R)-2- a [protein]-L- palmitoyl-CoA an S-sulfanyl-[L- N -octanoyl-L-lysine thiamine phosphate D-alanyl-D-alanine DMAPP an adenosine maltohexaose asp sn-glycerol pyrimidinemethanol kinase: LOOC260_RS06195 cysteine ligase CoaBC: 2-dehydropantoate LOOC260_RS04995 LOOC260_RS11405 L-alanyl-γ-D-glutamyl-L-lysine in 16S rRNA hydroxy fatty acid methionine cysteine desulfurase] synthase: NAD(+) in tRNA 16S rRNA D-2- bifunctional (R)-4'- LOOC260_RS04960 peptide-methionine bifunctional dihydrofolate reductase: 2-dehydropantoate LOOC260_RS10695 diphosphatase: ribose-5-phosphate (cytosine(967)-C(5) hydroxyisocaproate aspartate hydroxymethylpyrimidine hydroxymethylpyrimidine phosphopantothenoyl- D-xylulose isomerase RpiA: alpha-glucosidase: (S)-S-oxide reductase: LOOC260_RS02260 a [lipoyl-carrier 2-reductase: LOOC260_RS08845 decanoyl-CoA UDP-N-acetylmuramoyl- tRNA (adenosine(37)-N6) )-methyltransferase dehydrogenase: aminotransferase: kinase/ kinase/ L-cysteine 5-phosphate LOOC260_RS02180 LOOC260_RS09330 LOOC260_RS05350 dihydrofolate reductase: protein]-N 6 -[(R)- LOOC260_RS09510 thiamine tripeptide--D-alanyl- -dimethylallyltransferase RsmB: LOOC260_RS09255 a protein-L- LOOC260_RS09260 an S-sulfanyl-[cysteine phosphomethylpyrimidine NMN [+ 3 isozymes] phosphomethylpyrimidine bifunctional β phosphate acyl-CoA D- alanine ligase: MiaA: LOOC260_RS04535 LOOC260_RS04975 a 2-oxo methionine- LOOC260_RS05475 dihydrolipoyl]-L-lysine -alanine (R)-pantoate oxaloacetate desulfurase]-[disordered- kinase: LOOC260_RS06195 kinase: LOOC260_RS10700 glycine cleavage phosphopantothenoylcysteine D-ribose 5- dehydrogenase: LOOC260_RS01920 a 5-methylcytosine 967 carboxylate serine 5'-nucleotidase: (S)-S-oxide form scaffold a 7,8-dihydrofolate system proteina 5-methyltetrahydrofolate H: decarboxylase/ phosphate LOOC260_RS10630 in 16S rRNA bifunctional hydroxymethyltransferase: glyA 6 37 D-glucopyranose maltopentaose protein] complex HMP-P LOOC260_RS07685 phosphopantothenate-- LOOC260_RS07240 α N -dimethylallyladenosine [cysteine desulfurase]-S- hydroxymethylpyrimidine transketolase: (2E)-dec-2-enoyl-CoA UDP-N-acetyl- -D-muramoyl-L-alanyl- cysteine ligase CoaBC: 1-(β-D γ in tRNA sulfanylcysteine:[acceptor kinase/ bifunctional LOOC260_RS03705 -D-glutamyl-L-lysyl-D-alanyl-D-alanine LOOC260_RS04960 thiamine ribofuranosyl) protein]-cysteine phosphomethylpyrimidine hydroxymethylpyrimidine thymidylate synthase: trans-∆ 2 -decenoyl- (R)-pantothenate nicotinamide D-sedoheptulose D-glyceraldehyde sulfurtransferase: kinase: LOOC260_RS10700 kinase/ LOOC260_RS05480 thiamine CoA hydratase: a 3,5,7,9,11,13,15- a protein-L- a [protein]- 4'-phosphopantetheine 7-phosphate 3-phosphate seleno-L- maltotriose DNA with lesion LOOC260_RS06630 phosphomethylpyrimidine diphosphokinase: LOOC260_RS09865 coenzyme A VibB hepta-oxo- methionine- L-tyrosine HMP-P type I pantothenate homocysteine a [cysteine desulfurase]- kinase: LOOC260_RS06195 bifunctional 5,10- pantetheine- LOOC260_RS05000 (S)-3- hexadecanoyl-[PKS-acp] (R)-S-oxide excinuclease ABC phosphate a (6S)-5-formyltetrahydrofolate kinase: transaldolase: 5-methyltetrahydropteroyltriglutamate- S-sulfanyl-[disordered- methylene-tetrahydrofolate phosphate hydroxydecanoyl-CoA aldo/keto reductase: peptide-methionine subunit UvrC: protein-tyrosine- bifunctional bifunctional 5-(2-hydroxyethyl) LOOC260_RS09175 thiamine LOOC260_RS10315 - homocysteine S-methyltransferase: alpha-glucosidase: form scaffold oxythiamine methylenetetrahydrofolate dehydrogenase/5,10- 5-formyltetrahydrofolate adenylyltransferase: LOOC260_RS08865 (R)-S-oxide reductase: LOOC260_RS06385 phosphatase: hydroxymethylpyrimidine hydroxymethylpyrimidine -4-methylthiazole (R)-4'- diphosphate LOOC260_RS00480 holo-ACP synthase: LOOC260_RS09330 protein] complex reductase [NAD(P)H]: methylene-tetrahydrofolate cyclo-ligase: transaldolase: [+ 10 isozymes] LOOC260_RS05365 LOOC260_RS10300 kinase/ LOOC260_RS06470 [+ 3 isozymes] cysteine desulfurase: thiaminase II: kinase/ hydroxyethylthiazole LOOC260_RS10620 cyclohydrolase: phosphopantothenate LOOC260_RS05585 5-methyltetrahydropteroyltriglutamate- LOOC260_RS01930 [+ 3 isozymes] 9-hydroxy-3,5,7,11,13,15- a [protein]-L- DNA without a [protein]- LOOC260_RS04505 3'-dephospho- thiamine diphosphate LOOC260_RS06625 phosphomethylpyrimidine phosphomethylpyrimidine kinase: - homocysteine S-methyltransferase: hexaoxohexadecanoyl- methionine L-tyrosine LOOC260_RS10710 LOOC260_RS04890 biosynthesis I (E. coli) lesion [+ 2 isozymes] kinase: LOOC260_RS06195 kinase: LOOC260_RS10700 LOOC260_RS10705 a 5,10-methylenetetrahydrofolate a 5,10-methenyltetrahydrofolate CoA D-erythrose 3-oxodecanoyl-CoA LOOC260_RS10625 [PKS-acp] an S-sulfanyl-[cysteine 5-(2-hydroxyethyl) dephospho- F6P a holo-[VibB aryl- D-glucopyranose maltose bifunctional 4-methyl-5-(2- 2-[(2R,5Z)- 4-phosphate SeMet 3',5'-ADP desulfurase]-S- -4-methylthiazole HMP-PP bifunctional 5,10- CoA kinase: 2-carboxy-4- carrier protein] hydroxymethylpyrimidine phosphooxyethyl)thiazole transketolase: sulfanyl-[disordered- hydroxyethylthiazole methylene-tetrahydrofolate LOOC260_RS04325 menaquinol-6 biosynthesis methylthiazol-5(2H kinase/ LOOC260_RS03705 form scaffold kinase: dehydrogenase/5,10- )-ylidene]ethyl phosphomethylpyrimidine thiamine phosphate coenzyme A HMP-PP octanoyl-CoA protein] complex LOOC260_RS10705 methylene-tetrahydrofolate demethylmenaquinol-6 phosphate D-glyceraldehyde D-arabinofuranose (2Z)-2- [cysteine desulfurase]-S- kinase: LOOC260_RS10700 synthase: a homogalacturonan [DNA] maltopentaose a ribonucleoside a D-hexose 4-methyl-5-(2- cyclohydrolase: demethylmenaquinone 3-phosphate 5-phosphate hydroxypenta- sulfanylcysteine:[acceptor LOOC260_RS10695 Glycolysis acyl-CoA 5'-monophosphate phosphooxyethyl) methyltransferase: thiamine phosphate 2-dehydro-3- 2,4-dienoate protein]-cysteine HMP-PP L-cysteine biosynthesis LOOC260_RS04890 dehydrogenase: 2-keto-4-pentenoate glucokinase: thiazole LOOC260_RS00725 synthase: polygalacturonase: alpha-glucosidase: deoxyphosphooctonate 5'-nucleotidase: sulfurtransferase: VI (from L-methionine) 10 LOOC260_RS10630 hydratase: LOOC260_RS04520 an N -formyltetrahydrofolate glycolysis III (from glucose) exodeoxyribonuclease aldolase: LOOC260_RS07240 LOOC260_RS06630 thiamine phosphate menaquinol-6 LOOC260_RS10695 LOOC260_RS10130 LOOC260_RS09330 a [cysteine thiamine phosphate III: LOOC260_RS08020 LOOC260_RS02835 LOOC260_RS06575 lipoate salvage II (2E)-oct-2-enoyl-CoA polygalacturonase: [+ 3 isozymes] D-hexose 6- desulfurase]-(S- synthase: met a ribonucleoside (S)-4-hydroxy- thiamine diphosphate salvage IV (yeast) thiamine D-glucopyranose LOOC260_RS02845 KDO-8P phosphate sulfanyl) -[disordered- LOOC260_RS10695 methionine a [lipoyl-carrier 2-oxopentanoate 2 phosphate crotonase: a 2'- form scaffold adenosyltransferase: protein]-N 6 - glucokinase: LOOC260_RS09865 deoxyribonucleoside [DNA] D-glucopyranose maltotetraose protein] complex thiamine LOOC260_RS03965 thiamine lipoyl-L-lysine LOOC260_RS04520 thiamine diphosphate (S)-3- a homogalacturonan a homogalacturonan 5'-monophosphate phosphate SAM tetrahydrofolate biosynthesis D-glucopyranose hydroxyoctanoyl-CoA 6-hydroxymethyl-dihydropterin S-adenosyl-L-methionine cycle I thiaminase II: (R)-lipoate thiamine 6-phosphate diphosphate biosynthesis I (7,8-dihydropterin- (2Z)-2- a [cysteine desulfurase]- LOOC260_RS10710 diphosphate a single RNase R degradation maltoheptaose a double-stranded α 6-yl)methyl lipoate--protein ligase: glucose-6- -D-lyxopyranose hydroxyhexa- a quinone 4-aminobenzoate SAM stranded DNA substrate RNA oligonucleotide [scaffold protein- diphosphate LOOC260_RS09695 phosphate bifunctional D-lyxose/D- 4-amino-2-methyl-5- 5-(2-hydroxyethyl) 2,5-dienoate NADPH:quinone (2Fe-2S)] complex GTP isomerase: pgi 3-oxooctanoyl-CoA mannose family 2-keto-4-pentenoate glutathione biosynthesis SAH pyrimidinemethanol -4-methylthiazole [+ 2 isozymes] oligoribonuclease/PAP dihydropteroate exodeoxyribonuclease alpha-glucosidase: hydratase: reductase: GTP cyclohydrolase F6P ribonuclease R: phosphatase NrnA: sugar isomerase: bifunctional hydroxyethylthiazole methionine VII: LOOC260_RS04895 LOOC260_RS09330 LOOC260_RS06090 I FolE: 5'-methylthioadenosine/ synthase: (lipoyl)adenylate LOOC260_RS08060 LOOC260_RS07420 LOOC260_RS09875 LOOC260_RS06575 7,8- hydroxymethylpyrimidine kinase: adenosyltransferase: LOOC260_RS04900 [+ 3 isozymes] (S)-4-hydroxy- a [co-chaperone]- LOOC260_RS06255 cys glu adenosylhomocysteine LOOC260_RS06240 a nucleoside 5'- D-xylulose a semiquinone dihydroneopterin kinase/ LOOC260_RS10705 lipoate--protein ligase: LOOC260_RS03965 2-oxohexanoate [scaffold protein- nucleosidase: monophosphate 3'-triphosphate phosphomethylpyrimidine 4-methyl-5-(2- LOOC260_RS02965 hexanoyl-CoA (2Fe-2S)] complex LOOC260_RS06635 7,8- a single-stranded a nucleoside 5'- kinase: LOOC260_RS06195 phosphooxyethyl) [+ 2 isozymes] β-D-fructose 1,6- a ribonucleoside a diribonucleotide D-glucopyranose maltohexaose bifunctional glutamate- dihydropteroate oligodeoxyribonucleotide monophosphate SSQ1 chaperone: S-ribosyl-L- thiazole a [glycine- met SAH bisphosphate acyl-CoA 5'-monophosphate -cysteine ligase bifunctional LOOC260_RS05750 homocysteine thiamine phosphate bifunctional cleavage complex dehydrogenase: 7,8- GshA/glutathione hydroxymethylpyrimidine a [chaperone-ATP]- synthase: folylpolyglutamate H protein] N 6 - LOOC260_RS10630 dihydroneopterin synthetase GshB: S-ribosylhomocysteine kinase/ [co-chaperone]- LOOC260_RS10695 synthase/dihydrofolate lipoyl-L-lysine 5-methyltetrahydropteroyltriglutamate- 5'-methylthioadenosine/ a pseudouridine 1915 (2Z,4E)-2- a supercoiled 3'-phosphate LOOC260_RS09030 lyase: trans-hex-2-enoyl-CoA coenzyme A an apo [peptidyl- acetoacetate succinyl-CoA an mRNA [scaffold protein- phosphomethylpyrimidine synthase: - homocysteine S-methyltransferase: adenosylhomocysteine in 23S rRNA thr hydroxyhexa- duplex DNA glutamate-- LOOC260_RS08185 kinase: LOOC260_RS10700 thiamine nucleosidase: carrier protein] 2,4-dienedioate (2Fe-2S)] complex LOOC260_RS07545 LOOC260_RS00480 triose-phosphate 23S rRNA bifunctional threonine mRNA helicase SNF2: cysteine ligase: phosphate LOOC260_RS06635 crotonase: 4-oxalocrotonate 7,8-dihydrofolate 5-methyltetrahydropteroyltriglutamate- isomerase: (pseudouridine(1915)- ammonia-lyase/L-serine interferase PemK: LOOC260_RS05985 LOOC260_RS09655 L-homocysteine HMP-P a [lipoyl-carrier LOOC260_RS09865 3-oxoacid CoA- tautomerase: SSQ1 chaperone 6 N(3))-methyltransferase LOOC260_RS11245 D-erythro-7,8- monoglutamate protein]-N - - homocysteine S-methyltransferase: LOOC260_RS08090D-glyceraldehyde holo-ACP synthase: transferase: ammonia-lyase TdcB: LOOC260_RS05115 [+ 4 isozymes] DHAP (S)-3- RlmH: ATPase: dihydroneopterin bifunctional LOOC260_RS10625 L-homocysteine S-ribosyl-L-homocysteine 3-phosphate LOOC260_RS01930 LOOC260_RS09495 a single γ lipoyl-L-lysine LOOC260_RS09845 an mRNA fragment (3E)-2-oxohex- LOOC260_RS05750 -L-glutamyl- hydroxyhexanoyl-CoA 3 LOOC260_RS00175 dihydroneopterin hydroxymethylpyrimidine an N - 2-oxobutanoate 3-enedioate stranded DNA L-cysteine thiamine type I glyceraldehyde- aldolase: kinase/ methylpseudouridine 1915 a [chaperone- 3-phosphate a holo [peptidyl- bifunctional glutamate- phosphomethylpyrimidine 3',5'-ADP acetoacetyl-CoA succinate an [2Fe-2S] LOOC260_RS06265 L-cystathionine thiamine a 7,8-dihydrofolate dehydrogenase: in 23S rRNA ADP]-[disordered- -cysteine ligase kinase: LOOC260_RS06195 carrier protein] cluster protein 6-(hydroxymethyl) diphosphokinase: LOOC260_RS08135 form scaffold dihydrofolate S-ribosylhomocysteine 3-oxohexanoyl-CoA GshA/glutathione cystathionine bifunctional LOOC260_RS05000 folate polyglutamylation thiamine diphosphate protein] complex -7,8-dihydropterin reductase: lyase: LOOC260_RS08185 synthetase GshB: gamma-synthase: hydroxymethylpyrimidine biosynthesis II (Bacillus) 13-DPG non-chaperonin 2-amino-4-hydroxy-6- thiamine LOOC260_RS02260 an apo-[LYS2 L- (3E)-5-chloro-2- LOOC260_RS09030 LOOC260_RS01810 kinase/ coenzyme A a 3-oxo acid succinyl-CoA stachyose a nucleoside trans-caffeate methylglyoxal molecular hydroxymethyldihydropteridine diphosphate a tetrahydrofolate 2-(2-carboxy-4- 2-aminoadipyl- oxopent-3-enoate phosphomethylpyrimidine dihydrofolate phosphoglycerate triphosphate chaperone ATPase: diphosphokinase: glutathione methylthiazol-5- carrier-protein] glyoxalase: cys reductase: HMP-PP kinase: nucleotide 2-keto-4-pentenoate phenolic acid LOOC260_RS05750 LOOC260_RS06260 kinase: LOOC260_RS10700 yl)ethyl phosphate LOOC260_RS05475 formate-- bifunctional serine butanoyl-CoA 3-oxoacid CoA- pyrophosphohydrolase: hydratase: decarboxylase: LOOC260_RS06190 an [Fe-S cluster (7,8-dihydropterin- LOOC260_RS08130 alpha-galactosidase: HMP-PP tetrahydrofolate ligase: folylpolyglutamate hydroxymethyltransferase: glyA holo-ACP synthase: transferase: LOOC260_RS06395 LOOC260_RS06575 LOOC260_RS00370 [+ 3 isozymes] 6-yl)methyl thiamine phosphate acyl-CoA LOOC260_RS06045 biosynthesis a tetrahydrofolate LOOC260_RS05285 3-phospho-(R)-glycerate LOOC260_RS01930 5-chloro-4-hydroxy- 3,4- di-trans,poly-cis synthase/dihydrofolate synthase: dehydrogenase: LOOC260_RS09845 a nucleoside 5'- (R)-lactate chaperone]-ATP diphosphate a 5,10- 2-oxopentanoate dihydroxystyrene -undecaprenyl synthase: LOOC260_RS10695 LOOC260_RS10630 monophosphate NAD menaquinol-7 biosynthesis 10 phosphoglyceromutase: α-D- phosphate biosynthesis an N - LOOC260_RS07545 methylenetetrahydrofolate NADH repair a holo-[LYS2 L- raffinose phosphorylation and gpmA 3',5'-ADP a 2,3,4-saturated galactopyranose all-trans- (2E,6E)-farnesyl formyltetrahydrofolate bifunctional crotonyl-CoA 2-aminoadipyl- succinate IPP thiamine 3-oxoacyl-CoA transhydrogenation pyridoxal 5'-phosphate salvage I bifunctional folylpolyglutamate carrier-protein] heptaprenyl 1,4-dihydroxy- diphosphate a tetrahydrofolate phosphate NADH 2-phospho-D-glycerate + enoyl-CoA hydratase: thioredoxin pathway NAD diphosphate 2-naphthoate folylpolyglutamate synthase/dihydrofolate lipoate salvage I synthase/dihydrofolate synthase: LOOC260_RS09865 NAD kinase: pyridoxine pyridoxamine isoprenyl transferase: phosphopyruvate a [release factor]- (R)-10- phosphoenol LOOC260_RS07545 coenzyme A an apo-[aryl- NADP + coenzyme A raffinose a DNA segment an oxidized LOOC260_RS06780 LOOC260_RS05835 synthase: hydratase: (S)-3- base-degraded (R)-lipoate carrier protein] L-glutamine Hydroxystearate pyruvate thioredoxin NADP + pyridoxal kinase: pyridoxal kinase: LOOC260_RS07545 a 5,10- NAD(P)H-hydrate LOOC260_RS05390 hydroxybutanoyl-CoA peptide chain release thiamine salvage thiamine lipoate--protein ligase: LOOC260_RS00745 LOOC260_RS00745 di-trans,octa-cis 10 recombinase RecA: oleate hydratase: pyruvate kinase: an N - methylenetetrahydrofolate diphosphate LOOC260_RS09695 epimerase: (R)-NADHX phosphopyruvate factor N(5)-glutamine NAD(P) demethylmenaquinol-7 -undecaprenyl CoA-disulfide alpha-galactosidase: LOOC260_RS07470 LOOC260_RS00470 LOOC260_RS05580 formylaminopyrimidine pyridoxal pyridoxine pyridoxamine formyltetrahydrofolate [+ 2 isozymes] LOOC260_RS00660 hydratase: holo-ACP synthase: methyltransferase: transhydrogenase: diphosphate reductase: LOOC260_RS06045 thioredoxin- demethylmenaquinone 5'-phosphate 5'-phosphate acyl carrier (lipoyl)adenylate LOOC260_RS08085 LOOC260_RS01930 LOOC260_RS07795 a DNA segment in LOOC260_RS05070 LOOC260_RS09125 a [release factor]-N 5 oleate pyruvate disulfide reductase: methyltransferase: protein activation (S)-NADHX acetoacetyl-CoA reverse orientation LOOC260_RS05075 aminomethylpyrimidine phosphoenolpyruvate -methyl-L-glutamine LOOC260_RS08210 LOOC260_RS00725 pyridoxal kinase: menaquinol-9 biosynthesis lipoate--protein ligase: fatty acid β-oxidation I (generic) α-D- sucrose LOOC260_RS05080 thiaminase II: LOOC260_RS00745 di-trans,octa-cis an apo acyl- LOOC260_RS09695 NAD(P)H-hydrate a holo-[aryl- menaquinol-8 biosynthesis 3',5'-ADP CoA-disulfide NADPH H + galactopyranose LOOC260_RS10710 menaquinol-7 -undecaprenyl carrier protein [+ 2 isozymes] dehydratase: pyruvate kinase: a (3Z)-alk-3- carrier protein] NADPH holo-ACP synthase: demethylmenaquinol-9 a reduced thiamine diphosphate phosphate a [lipoyl-carrier LOOC260_RS04000 LOOC260_RS05580 enoyl-CoA 4-amino-2-methyl-5- PLP demethylmenaquinone 6 salvage III LOOC260_RS01930 demethylmenaquinol-8 protein]-N - acetyl-CoA thioredoxin pyrimidinemethanol a holo acyl- methyltransferase: pyruvate demethylmenaquinone lipoyl-L-lysine NADH an α-D- (R)-5- 2,3- carrier protein LOOC260_RS00725 coenzyme A AsbD acyl- melibionate pyruvate 4-coumarate thiamine methyltransferase: galactoside phosphomevalonate dihydroxybenzoate menaquinol-9 carrier protein thiamine LOOC260_RS00725 a (2E)-2- phosphomevalonate o-pyrocatechuate phenolic acid pyruvate carboxylase: diphosphokinase: menaquinol-8 enoyl-CoA enoyl-CoA hydratase: kinase: decarboxylase: decarboxylase: a 2,3,4-saturated alpha-galactosidase: alpha-galactosidase: LOOC260_RS06485 LOOC260_RS05000 acyl-CoA synthetase: LOOC260_RS09865 LOOC260_RS05150 LOOC260_RS00305 LOOC260_RS00370 thiamine fatty acid acyl-CoA holo-ACP synthase: LOOC260_RS06045 LOOC260_RS06045 LOOC260_RS01695 a 2,3,4- diphosphate dehydrogenase: saturated (3R)-3- LOOC260_RS01930 (R)-mevalonate acyl-CoA synthetase: catechol oxaloacetate 4-vinylphenol LOOC260_RS10630 a 2,3,4- hydroxyacyl-CoA diphosphate LOOC260_RS01720 α-D- a non α-D- a 2,3,4-saturated saturated (3S)-3- D-gluconate a holo-[AsbD acyl- galactopyranose galactosylated galactopyranose fatty acyl CoA hydroxyacyl-CoA 3',5'-ADP carrier protein] galactose acceptor

coenzyme A (2-hydroxyphenyl)methyl 1-hydroxy- an [amino group carrier protein]- aldehydo-D- a 2,3,4-saturated a 2,3,4-saturated coenzyme A [EntB aryl- γ a cytosine in DNA NaMN (R)-NADPHX 6-oxocyclohex-2-ene-1-carboxylate C-terminal- -(L-glutamate 5- galacturonate fatty acyl CoA 3-oxoacyl-CoA carrier protein] glucuronate isomerase: semialdehyde-2-yl)-L-glutamateN-acetyl-gamma- DNA (cytosine-5-)- NAD(P)H-hydrate LOOC260_RS10155 5'-nucleotidase: glutamyl-phosphate methyltransferase: epimerase: carboxylesterase: glucuronate isomerase: LOOC260_RS07240 holo-ACP synthase: reductase: LOOC260_RS08955 LOOC260_RS00660 LOOC260_RS08065 LOOC260_RS00860 LOOC260_RS01930 an [amino group carrierLOOC260_RS00150 protein]- a 5-methylcytosine β-D- Inorganic Nutrient (S)-NADPHX C-terminal-γ-(5-phospho- D-tagaturonate in DNA ribosylnicotinate acetyl-CoA Metabolism 1-hydroxy-6-oxocyclohex- L-glutamyl)-L-glutamate Amine and Polyamine Degradation 3',5'-ADP a holo-[EntB aryl- salicyl alcohol urea cycle carrier protein] 2-ene-1-carboxylate

4-aminobutanoate degradation I N-acetylglucosamine 4-aminobutanoate arg a 5S rRNA a secondary degradation I degradation III coenzyme A [EntF L-seryl- a ribonucleoside sn-glycerol 7,8-dihydropterin L-cysteate carrier protein] precursor diphosphate 3-phosphate alcohol 4-aminobutanoate N-acetyl-D- class 1b ribonucleoside- 4-aminobutanoate glyceraldehyde 3- aspartate aspartate glucosamine diphosphate reductase: guanine deaminase: carbonyl reductase: aspartate phosphate reductase: aminotransferase: aminotransferase 6-phosphateN-acetylglucosamine- ribonuclease M5: LOOC260_RS08430 LOOC260_RS03570 LOOC260_RS00100 aminotransferase holo-ACP synthase: LOOC260_RS09900 LOOC260_RS09260 family protein: 6-phosphate LOOC260_RS01785 LOOC260_RS08435 family protein: LOOC260_RS01930 a 2'- L-glyceraldehyde 7,8- LOOC260_RS04150 deacetylase: 3-sulfopyruvate a ketone LOOC260_RS04150 argininosuccinate ammonium deoxyribonucleoside 3-phosphate dihydrolumazine aspartate D-glucosamineLOOC260_RS02080 lyase: aspartate a holo-[EntF a double-stranded 5'-diphosphate aminotransferase 6-phosphate LOOC260_RS08175 carbamoyl- a mature 5S-rRNA aminotransferase 3',5'-ADP L-seryl-carrier oligonucleotide family protein: L-arginino- phosphate synthase: family protein: L-ornithine protein] LOOC260_RS10925 succinate LOOC260_RS00140 succinate LOOC260_RS10925 succinate LOOC260_RS00145 semialdehyde α -D-glucosamine semialdehyde argininosuccinate 5-amino-4- a peptidoglycan 4-(cytidine 5'- 3-phospho- a supercoiled NAD-dependent [+ 2 isozymes] PRPP wound RNA (S)-NADPHX 6-phosphate synthase: imidazolecarboxyamide dimer (generic) diphospho)-2-C- (R)-glycerate duplex DNA succinate- glucosamine-6- LOOC260_RS08180 ornithine carbamoyl methyl-D-erythritol4-(cytidine 5'- 3-phosphoglycerate ATP-dependent NAD(P)H-hydrate semialdehyde DNA/RNA helicase: phosphate deaminase: carbamoyltransferase: phosphate endolytic diphospho)-2-C-methyl- dehydrogenase: DNA helicase RecQ: dehydratase: dehydrogenase: adenine LOOC260_RS08310 LOOC260_RS07965 LOOC260_RS00170 transglycosylase MltG: D-erythritol kinase: LOOC260_RS09520 LOOC260_RS05535 LOOC260_RS04000 LOOC260_RS05895 succinate phosphoribosyltransferase: LOOC260_RS04475 LOOC260_RS01800 a single F6P ornithine LOOC260_RS06355 2-phospho-4-(cytidine 3-phosphooxypyruvate an unwound RNA NADPH succinate carbamoyltransferase: 5'-diphospho)-2-C- stranded DNA LOOC260_RS10780 GlcNAc-1,6-anhydro- methyl-D-erythritol L-citrulline a lipid II AICAR MurNAc-pentapeptide

Carbohydrate Degradation a [2-oxoglutarate a double acetoacetyl-CoA acetyl-CoA H O isoprimeverose xylan ferulate (S)-malate D-galactose degradation I (Leloir pathway) 2 dehydrogenase E2 protein] 2-deoxy-D-glucose 6- stranded DNA N 6 -dihydrolipoyl-L-lysine phenolic acid class II fumarate phosphate degradation dihydrolipoyl DNA gyrase subunit A: alpha-xylosidase: β-D-galactopyranose decarboxylase: hydratase: 2-deoxy-D- hydroxymethylglutaryl- alpha-xylosidase: dehydrogenase: LOOC260_RS00030 LOOC260_RS09310 CoA synthase: LOOC260_RS00370 LOOC260_RS06085 galactose mutarotase: glucose 6- LOOC260_RS09310 LOOC260_RS06515 LOOC260_RS05900 a [2-oxoglutarate a negatively α-D-xylopyranose LOOC260_RS09325 phosphate 4-vinylguaiacol fumarate dehydrogenase E2 supercoiled DNA [+ 2 isozymes] 2-deoxy- L-arabinose degradation I protein] N 6 -lipoyl-L-lysine D-glucopyranose α-D-xylopyranose α-D-galactopyranose D-glucose HMG-CoA L-arabinopyranose galactokinase: L-arabinose isomerase: LOOC260_RS03730 2-deoxy- a mature peptidoglycan an [amino group carrier protein]-C- dCDP LOOC260_RS09910 (n) a 2'-deoxyribonucleoside a uridine in tRNA maltose a kanamycin α D-glucono- (meso-DAP containing) terminal-γ-(L-glutamyl)-L-glutamate -D-galactose α L-ribulose class 1b ribonucleoside- UDP- -D-glucose 1,5-lactone deoxynucleoside kinase: tRNA dihydrouridine alpha-glucosidase: aminoglycoside 1-phosphate acetylglutamate kinase: diphosphate reductase: LOOC260_RS02500 synthase DusB: LOOC260_RS09330 phosphotransferase: endolytic transglycosylase LOOC260_RS00160 LOOC260_RS08430 deoxynucleoside kinase: LOOC260_RS02005 LOOC260_RS08435 [+ 3 isozymes] LOOC260_RS05695 MltG: LOOC260_RS04475 an [amino group carrier protein]- LOOC260_RS04030 a kanamycin L-ribulose 5- a 5,6-dihydrouridine CDP D-glucopyranose 2-deoxy-D- C-terminal-γ-(5-phospho- a 2'-deoxyribonucleoside 3'-phosphate gluconate phosphate in tRNA a mature peptidoglycan GlcNAc-1,6-anhMurNAc- L-glutamyl)-L-glutamate 5'-monophosphate (n) 2-deoxy-D-gluconate L-ribulose-5- (meso-DAP containing) L-Ala-γ-D-Glu-DAP-D-Ala 3-dehydrogenase: phosphate LOOC260_RS03750 4-epimerase 2-amino-6-[1-hydroxyethyl]- 4-phosphooxy- UDP uridine [+ 2 isozymes] AraD: araD a folate (R)-mevalonate D-glucopyranose 3-dehydro- D-xylulose 7-methyl-7,8-dihydropterin L-threonine class 1b ribonucleoside- 2-amino-4-hydroxy-6- 3-phosphoserine/ dihydrofolate reductase: uridine kinase: 2-deoxy-D- 5-phosphate diphosphate reductase: phosphohydroxythreonine LOOC260_RS02260 mevalonate kinase: xylose isomerase: gluconate hydroxymethyldihydropteridine LOOC260_RS08430 LOOC260_RS04480 transaminase: LOOC260_RS05160 LOOC260_RS09275 diphosphokinase: dihydrofolate reductase: LOOC260_RS08435 LOOC260_RS06260 LOOC260_RS09525 LOOC260_RS05475 UMP [1-(2-amino-7-methyl-4-oxo- (3R)-3-hydroxy-2-oxo- (R)-5- dUDP keto-D-fructose 7,8-dihydro-3H-pteridin- a 7,8-dihydrofolate phosphomevalonate UDP-glucose 4- maltose degradation 4 phosphooxybutanoate 6-yl)]ethyl diphosphate epimerase GalE: galactose-1-phosphate LOOC260_RS08360 maltose uridylyltransferase: maltose 34 UTP UDP-glucose phosphatidylglycerolphosphate a 5-carboxymethylaminomethyluridine a single 2'-deoxycytidine β-D-allopyranose phosphorylase: Leu LOOC260_RS03735 4-epimerase: (1-oleoyl, 2-palmitoyl) in tRNA stranded DNA deoxynucleoside kinase: nucleotide LOOC260_RS08695 LOOC260_RS10935 phosphatidylglycerophosphatase tRNA (cytidine(34)-2'- α-D-glucopyranose β-D-glucopyranose deoxyribonuclease IV: LOOC260_RS04030 pyrophosphohydrolase: D-ribose pyranase: UDP-α-D-galactose A: LOOC260_RS10495 O)-methyltransferase: 1-phosphate 1-phosphate LOOC260_RS05670 deoxynucleoside kinase: LOOC260_RS06395 LOOC260_RS02225 LOOC260_RS06750 beta- phosphatidylglycerophosphatase LOOC260_RS02500 UMP phospho- A: LOOC260_RS07215 a 5-carboxymethylaminomethyl- β-D-allofuranose phosphoglucomutase: 1-oleoyl-2-palmitoyl- 34 Leu a 5'-phosphooligonucleotide dCMP sugar mutase: 2'-O-methyluridine in tRNA LOOC260_RS10930 phosphatidylglycerol LOOC260_RS08205 ribose phosphorylation beta- D-glucopyranose phosphoglucomutase: β 6-phosphate -D-ribopyranose LOOC260_RS04080 D-ribose pyranase: β-D-glucose LOOC260_RS02225 6-phosphate β-D-ribofuranose D-xylose degradation I

melibiose degradation D-xylose D-ribofuranose xylose isomerase: LOOC260_RS09275 ribokinase: melibiose D-xylulose LOOC260_RS04230 D-ribofuranose alpha-galactosidase: xylulokinase: 5-phosphate LOOC260_RS06045 LOOC260_RS09270 D-xylulose D-galactopyranose D-glucopyranose 5-phosphate a branched- chain glycine betaine amino acid gly N-acetyl-α-D- a branched- a carbohydrate an L-sorbose 1-phosphate glycine betaine glycine betaine glycine betaine putrescine a sugar 6- a sugar 6- D-fructose an aliphatic D-mannose a nucleotide glutamate chain D-fructose 1-phosphate glucosamine a nucleoside (RS)-malate a sulfonate ammonium a carbohydrate 6-phosphate D-glucose gly gly gly spermidine phosphate phosphate 1-phosphate sulfonate predicted amino acid D-mannose 6-phosphate 6-phosphate predicted ABC ABC transporter predicted ABC transporter RS01650 RS04925 RS10560 RS09400 RS05755 RS02520 RS04190 RS10020 RS04200 RS01725 of a RS06210 transporter of RS00260 RS04205 RS04195 RS02955 RS07885 RS01000 RS02145 RS01715 RS10580 of glycine/ branched- a carbohydrate glycine chain betaine amino acid ammonium

α glycine betaine glycine betaine glycine betaine putrescine an aliphatic a branched- a branched- L-sorbose N-acetyl- -D- glycine betaine a nucleotide a sugar a sugar D-fructose a carbohydrate a carbohydrate D-mannose D-glucose a nucleoside (RS)-malate a sulfonate gly gly gly gly spermidine glutamate sulfonate chain chain D-fructose glucosamine amino acid amino acid D-mannose This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.