Authors: Pallavi Subhraveti Ron Caspi Quang Ong Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_002025645Cyc: Curtobacterium pusillum AA3 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari D-mannitol phosphate phosphate phosphate putrescine glycine betaine glycine betaine ammonium ammonium Fe 2+ D-gluconate ammonium H + spermidine gly gly enterobactin predicted predicted PEP-driven ABC RS16670 RS10785 RS04295 RS03485 RS01160 RS13465 RS13470 AtpD RS14785 RS17505 RS12115 transporter transporter of D-mannitol of phosphate

putrescine glycine betaine glycine betaine ammonium ammonium phosphate phosphate Fe 2+ D-gluconate ammonium H + spermidine gly gly enterobactin D-mannitol 1-phosphate phosphate

Amino Acid Degradation Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis Degradation/ Macromolecule Modification lipoprotein posttranslational Utilization/ ditrans,octacis- 1-stearoyl- DNA combined 3-oxo-2-(cis- a (7Z,10Z,13Z a [protein]-L- modification L-valine degradation I Assimilation - Other a 3-oxoglutaryl- (S)-1-pyrroline- [2Fe-2S] iron-sulfur cluster biosynthesis L-glutamine O-acetyl-L-serine hydrogen selenide a palmitoyl-[acp] sn-glycerol with exogenous 2'-pentenyl)- a protein H O diphosphate ,16Z,19Z)-3- met menaquinol-9 biosynthesis 1,4-dihydroxy-2- Aminoacyl-tRNA Charging L-methionine degradation L-serine degradation L-arginine degradation X (arginine a tRNA precursor CTP ATP undecaprenyldiphospho- acetyl-CoA 2 dITP ITP [acp] methyl ester 5-carboxylate methionine superpathway of tetrahydrofolate biosynthesis demethylmenaquinol- molybdenum cofactor biosynthesis di-trans,poly-cis-undecaprenyl lipoate biosynthesis a [prolipoprotein]- acrylonitrile peptide- I (to L-homocysteine) degradation I bifunctional o- N-acetyl-(N- 1-acyl-sn-glycerol-3-phosphate DNA to form a cyclopentane-1- ATP-dependent inorganic 3-oxoacyl-ACP oxodocosa- 1-pyrroline-5- bifunctional 9 biosynthesis naphthoate biosynthesis phosphate biosynthesis and incorporation I monooxygenase pathway) acetyl-CoA C- non-canonical purine non-canonical purine L-cysteine degradation I CCA tRNA recombinational hexanoyl-CoA pyrophosphatase: 7,10,13,16,19- carboxylate methionine tRNA charging val acetylhomoserine/o- acetylglucosaminyl) 3-phosphate crossover junction Clp protease reductase FabG: 3-oxoacyl-ACP glutamate N- predicted L-cysteine desulfurase all-trans- demethylmenaquinol-9 nucleotidyltransferase: acyltransferase: NTP pyrophosphatase, NTP pyrophosphatase, (S)-S-oxide chorismate cys (2E,6E)-farnesyl demethylmenaquinol- L-asparagine prolipoprotein ser acetylserine sulfhydrylase: muramoyl-L-alanyl- acyltransferase: junction proteolytic subunit: BUE88_RS12210 BUE88_RS02435 pentaenoyl-[acp] dehydrogenase: acetyltransferase/ ABC GTP 2-carboxy-1,4- demethylmenaquinone met arg gln acrylonitrile endodeoxyribonuclease BUE88_RS08345 RdgB/HAM1 family: rdgB RdgB/HAM1 family: rdgB reductase FabG: nonaprenyl an octanoyl-[acp] biosynthesis III diacylglyceryl BUE88_RS11360 γ BUE88_RS12075 reductase: cysteine naphthoquinol isochorismate ATP diphosphate 8 biosynthesis I branched-chain methionine L-serine CTP synthase: BUE88_RS03525 -D-isoglutaminyl- BUE88_RS04005 RuvC: BUE88_RS01990 BUE88_RS17195 inorganic 3-oxoacyl-ACP BUE88_RS02435 amino-acid met transporter met diphosphate methyltransferase: lipoate-protein arginine-- acetyl-CoA C- NTP NTP msrA 1,4-dihydroxy- synthase: cysteine arg (tRNA-dependent) transferase: ammonia-lyase: BUE88_RS08675 CCA tRNA N-(β-D-asparaginyl)peptidoglycan pyrophosphatase: 1-pyrroline-5- acetyltransferase of L- desulfurase: BUE88_RS05490 tRNA ligase: amino acid adenosyltransferase: O-acetylhomoserine [+ 2 isozymes]1-stearoyl- Holliday junction ATP-dependent Clp reductase: 3-oxoacyl-ACP GTP 2-naphthoate ligase B: 2-carboxy-1,4- BUE88_RS02710 nucleotidyltransferase: di-trans,octa-cis a peptidoglycan acyltransferase: pyrophosphohydrolase: pyrophosphohydrolase: BUE88_RS05875 BUE88_RS05495 desulfurase: GTP di-trans,octa-cis aminotransferase: BUE88_RS02805 2-aminoprop-BUE88_RS10735 [+ 5 isozymes] aminocarboxypropyltransferase/ -L-lysyl-D-alanineglycosyltransferase: protease proteolytic BUE88_RS15140 BUE88_RS14775 carboxylate ArgJ: peptide- methionine cyclohydrolase I: menaquinol-9 a [lipoyl-carrierBUE88_RS03925 naphthoquinol BUE88_RS03190 an L-arginyl- asp 4-guanidinobutyramide 2-palmitoyl- resolution ofresolvase RuvX: 3-oxo-2-(cis-BUE88_RS01125 BUE88_RS11945 BUE88_RS11945 a (3R)-3- a (3R,7Z,10reductase:Z polyprenyltransferase: isochorismate a [prolipoprotein]- acrylamide a tRNA BUE88_RS19420 -undecaprenyl dimer acyl-carrier protein + BUE88_RS05875 -undecaprenyl 6 1,4-dihydroxy- BUE88_RS04210 SAM 2-enoate Glu cysteine synthase: BUE88_RS18770 subunit: clpP phosphate H dehydrogenase: BUE88_RS08755 methionine cysteine BUE88_RS10485 protein] N - [tRNA Arg ] aspartate-- sn-glycerol recombinationalBUE88_RS02905 2'-pentenyl)- hydroxyglutaryl- ,13Z,16Z,19ZBUE88_RS14775)-3- met RS11125 met BUE88_RS05515 diphosphate 2-naphthoate (S-diacylglyceryl) containing a diphosphate (tetrapeptide) dIMP IMP BUE88_RS18480 (S)-S-oxide cysteine Arg 3-methyl-2- BUE88_RS03670 cyclopentane-1- desulfurase: 7,8- demethylmenaquinol-9 2-succinyl-5- GTP 3',8- octanoyl-L-lysine a tRNA tRNA(Asn) ligase: -L-cysteine amidase: amidase: 3-phosphate junction a peptide a peptide [acp] methyl ester hydroxydocosa- N-acetylglutamate desulfurase: a carboxy- undecaprenyl- polyprenyltransferase: 3' CCA end reductase: BUE88_RS03730 dihydroneopterin cyclase MoaA: lipoyl BUE88_RS05585 oxobutanoate BUE88_RS03345 BUE88_RS03345 acetate L-selenocysteine formation of two (3-oxooctanoyl) 7,10,13,16,19- Glu synthase: enolpyruvyl- adenylated diphosphate BUE88_RS05515 an L-aspartyl- msrA 3'-triphosphate BUE88_RS03730 BUE88_RS07215 synthase: intact strands -CoA pentaenoyl-[acp] BUE88_RS12310 6-hydroxy-3- Asn signal a protein-L- an S-sulfanyl-[L- an [L-cysteine [small subunit of (8S)-3',8-cyclo-7,8- phosphatase: demethylmenaquinol-8 [tRNA ] N-acetyl-L- asn RS04310 asn lipA peptidase 2-iminopropanoate 4-guanidinobutanoate acrylate methionine- cysteine desulfurase] cyclohexene- desulfurase]-S- molybdopterin BUE88_RS02280 a [lipoyl-carrier dihydroguanosine Asp-tRNA(Asn) SAH methionine 1-carboxylic- di-trans,octa-cis 6 II: lspA (S)-S-oxide sulfanyl-L-cysteine synthase] 5'-triphosphate protein]-N - cysteine-- -undecaprenyl cys /Glu-tRNA(Gln) isobutanoyl-CoA 7,8- acid synthase: lipoyl-L-lysine tRNA ligase: signal cyclic pyranopterin amidotransferase adenosylhomocysteinase: L-threonine dihydroneopterin menD phosphate BUE88_RS09305 peptidase predicted monophosphate an L-cysteinyl- BUE88_RS04500 degradation II 1-stearoyl- a peptide with 3-oxo-2-(cis- (5E)-3-oxo- a (9Z)-3-oxo- a (5Z)-3- (R)-4-hydroxy- an S-sulfanyl-[cysteine subunit GatC: O-acetyl-L- a 2,3,4-saturated a 2,3,4-saturated 2- (+)-7-epi-jasmonoyl-CoA acetyl-CoA an unsulfurated a 3-oxoicosanoyl- a phosphate ABC efflux 3'-phosphate 2-succinyl-5- [tRNA Cys ] II: lspA 4-aminobutanoate methanethiol a stearoyl-[acp] sn-glycerol an N-terminal 2'-pentenyl)- cys dodec-5- an acetoacetyl-[acp] octadec-9- oxododec- 4-methyl-2- synthase menaquinol-10 biosynthesis BUE88_RS16595 adenosylhomocysteinase: pyruvate acetyl-CoA XTP monoester desulfurase]-[disordered- enolpyruvoyl-6- a thiocarboxylated Cys homoserine fatty acyl-[acp] lysophosphatidate [sulfur carrier] [acp] thiol transporter thiol MoaC: moaC a tRNA O-acetyl-L- 1-acyl-sn-glycerol- acetyl-CoA C- 1-acyl-sn-glycerol-3-phosphate Xaa-L-prolineXaa-Pro cyclopentane- cysteine enoyl-CoA 3-oxoacyl-ACP 3-oxoacyl-ACP enoyl-[acp]3-oxoacyl-ACP 5-enoyl-[acp]3-oxoacyl-ACP alkaline oxoglutarate form scaffold chorismate flavin biosynthesis I (bacteria and plants) [+ 2 isozymes] an (S-diacyl- BUE88_RS08940 thr acetyl-CoA C- acetyl-CoA C- 4-carboxy-4- of a thiol hydroxy-3-cyclohexene- [small subunit of cyclic all-trans- a lipoprotein acyltransferase: 1-butanoyl-CoA non-canonical purine 2-carboxy-1,4- methylacrylyl-CoA L-threonine 3- homoserine 3-phosphate 3-phosphate aminopeptidase: desulfurase: acyltransferase: reductase FabG: reductase FabG: reductase: reductase: phosphatase: hydroxy-2- protein] complex 1-carboxylate molybdopterin pyranopterin an L-asparaginyl- sn-glyceryl) signal peptide acyltransferase: NTP pyrophosphatase, group decaprenyl L-homocysteine sulfhydrolase: acyltransferase: BUE88_RS08345 acyltransferase: BUE88_RS16395 BUE88_RS03730 BUE88_RS02435 BUE88_RS02435 BUE88_RS14775 BUE88_RS14775 BUE88_RS15185 cysteine 7,8- 4-amino-4- naphthoquinol Asn -L-cysteinyl- dehydrogenase: BUE88_RS08345 oxoadipate synthase] phosphate diphosphate [tRNA ] BUE88_RS08345 RdgB/HAM1 family: rdgB desulfurase: dihydroneopterin deoxychorismate 1,4-dihydroxy- BUE88_RS02795 BUE88_RS07265 BUE88_RS04005 acetyl-CoA C- BUE88_RS04005 leucyl cysteine 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP Peptide RS13020 Peptide GTP [apolipoprotein] L-2-amino-3- acetyl-CoA C- alkaline aldolase/ 2-naphthoate aminoacyl-tRNA L-glutamate acyltransferase: acetyl-CoA C- NTP BUE88_RS05875 synthase: tRNA processing O-acetylhomoserine [+a 22,3,4-saturated isozymes] [+ 21-stearoyl-2- isozymes] aminopeptidase: desulfurase: acyltransferase: reductase: reductase: reductase FabG: reductase FabG: phosphatase: oxaloacetate dihydroneopterin (1R,6R)-6-hydroxy-2- polyprenyltransferase: gln hydrolase: degradation II oxobutanoate acyltransferase: pyrophosphohydrolase: BUE88_RS02740 (S)-3-hydroxy- BUE88_RS01125 BUE88_RS01030 BUE88_RS05875 BUE88_RS14775 BUE88_RS14775 BUE88_RS02435 BUE88_RS02435 BUE88_RS01865 decarboxylase: cysteine aldolase: folB GTP glycine cleavage aminocarboxypropyltransferase/ 1,2-diacyl-sn 3-oxo-2-(cis-2'-pentenyl)- stearoyl-sn a peptide with 3-oxo-2-(cis-BUE88_RS01125 BUE88_RS01125 a (3R)-3- a (3R)-3- a (3R,9Z)-3- a (3R,5Z)-3- succinylcyclohexa-2,4- BUE88_RS05515 BUE88_RS15865 glycine C- acyl-carrier protein acyl-carrier protein a proteinogenic a sulfurated (3E)-dec-3- BUE88_RS11945 desulfurase: 4-amino-4- cyclohydrolase an L-glutaminyl- a peptide isobutanoyl-CoA cysteine synthase: -glycerol 3- -glycerol 3- an N-terminal 2'-pentenyl)- ala hydroxybutanoyl- hydroxyicosanoyl- hydroxy-octadec- hydroxydodec- an alcohol ligK 2+ 2+ diene-1-carboxylate L-cysteine biosynthesis DMKH2-10 a polycistronic an N-acyl-(S- cyclopentane-1-(3-oxobutanoyl)-CoA acetyl-CoA Co RS15415 Co 6-(hydroxymethyl) Gln Glu acetyltransferase: amino acid [sulfur carrier] enoyl-CoA XMP BUE88_RS03730 deoxychorismate II: ribA molybdopterin NAD phosphorylation [tRNA ] a [glycine-cleavage complex BUE88_RS03670 phosphate phosphate L-proline cyclopentane-1- [acp] [acp] 9-enoyl-[acp] 5-enoyl-[acp] pyruvate -7,8-dihydropterin O-succinylbenzoate VI (from L-methionine) Gln asn tRNA precursor diacyl-sn-glyceryl) a [cysteine desulfurase]- 2,5-diamino-6- a tRNA 6 aspartate BUE88_RS02790 4-amino-4- and dephosphorylation demethylmenaquinone H protein] N -lipoyl-L-lysine acetate met (3-oxohexanoyl) S-sulfanyl-[disordered- 2-amino-4-hydroxy-6- (5-phospho-D- synthase: -L-cysteinyl- aminotransferase: methyltransferase: glycine -CoA deoxychorismate BUE88_RS05535 [lipoprotein] gly arg arg form scaffold hydroxymethyldihydropteridine ribosylamino) met NAD + (S)-3-hydroxy- dehydrogenase BUE88_RS09570 lyase: BUE88_RS05490 gcv system: gcvP protein] complex diphosphokinase: folK pyrimidin- methionine isobutanoate (aminomethyl- [+ 3 isozymes] RS03415 cysteine BUE88_RS17470 2-succinylbenzoate molybdopterin dihydrolipoyl Inorganic Nutrient (7,8-dihydropterin- 4(3H)-one adenosyltransferase: menaquinol-10 asp L-alanine a (2R)-2-hydroxy N-acetyl-D- a 3- a (9Z)-3- a (9Z)-3- 4-hydroxy- adenine alkaline a tRNA precursor 3-hydroxyisobutyrate transferring): gcvP Metabolism undecaprenyl- 3-oxo-(6Z,9Z,12Z,15Z,18Z) a [glutamine- ornithine ornithine desulfurase: gln exoribonuclease: dehydrogenase: degradation IV a [ThiI sulfur-carrier butanoyl-CoA acetyl-CoA O-ureido-L- a 3-oxohexacosanoyl- a 3-oxopimeloyl- butan-1-ol 6-yl)methyl o-succinylbenzoate- BUE88_RS02805 Glu glutaminyl-tRNA with a 5' extension dehydrogenase: diphospho-N- even numbered -tetracosapentaenoyl-CoA galactosamine cys asp oxododecanoyl- oxohexadec- oxooctacos- 4-methyl-2- BUE88_RS05875 4-aminobenzoate diaminohydroxyphosphoribosylaminopyrimidine dinucleotide phosphatase: NAD kinase: BUE88_RS17585 lpdA protein]-L-cysteine synthetase]- ATP homoserine [acp] [acp] methyl ester predicted diphosphate SAM biosynthesis via aspartate straight chain acetyl-CoA C- 6-phosphate acetyl-CoA C- [acp] 9-enoyl-[acp] 9-enoyl-[acp] NAD(P)- oxoglutarate deaminase: ribD -CoA ligase: molybdopterin BUE88_RS15185 and a long 3' trailer a tRNA precursor with BUE88_RS14745 urea cycle acetylmuramoyl- UDP-N-acetyl- cysteine L-tyrosine argininosuccinate 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP ABC cysteine BUE88_RS08685 geranyl diphosphate an L-glutamyl- N-acetylglucosamine- bifunctional 4-carboxy-4- nitrate nitrate BUE88_RS05520 molybdenumtransferase transamidation a 5' extension and ammonia- ala L-alanyl-γ-D- α-D-glucosamine 2,3,4-saturated acyltransferase: desulfurase: acyltransferase: reductase FabG: reductase FabG: reductase FabG: reductase FabG: reductase FabG: dependent alcohol transporter 5-amino-6-(5- alkaline NAD(+) kinase: biosynthesis Glu (S)-methylmalonate- L-aspartate long-chain fatty 6-phosphate glutamine-synthetase synthase: hydroxy-2- desulfurase: [tRNA ] a [glycine-cleavage lyase: aspA glutamyl-L-lysyl- undecaprenyldiphospho- fatty acid BUE88_RS08345 BUE88_RS01125 dehydrogenase: phospho-D- 4-(2'-carboxyphenyl) MoeA: BUE88_RS14930 glu a short 3' extension semialdehyde a [glycine-cleavage alanine acid--CoA ligase: BUE88_RS03730 BUE88_RS08735 BUE88_RS02435 BUE88_RS02435 BUE88_RS02435 BUE88_RS02435 BUE88_RS02435 of nitrate BUE88_RS03730 phosphatase: BUE88_RS12285 a tRNA Glu ribonucleaseribonuclease D: D:ribonuclease PH: complex H protein] N 6 - degradation I deacetylase: nagA adenylyltransferase/ oxoadipate MoO - ribonuclease complex H protein] N 6 arg D-alanyl-D-alanine muramoylpentapeptide beta-N- acetyl-CoA C- acetyl-CoA C- BUE88_RS01710 an S-sulfanyl-[cysteine ribosylamino)uracil -4-oxobutyryl-CoA 2 BUE88_RS01865 IPP glutamyl-tRNA Gln BUE88_RS01130 fumarate dehydrogenase: ald ditrans,octacis- BUE88_RS18710a (R)-2-hydroxy N-acetylglucosamine- cysteine deadenyltransferase: argininosuccinate 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP aldolase/ 7,8- molybdopterin BUE88_RS01130 BUE88_RS16550 P protein aminomethyldihydrolipoyl- acetylglucosaminyltransferase: desulfurase]-S- 5-amino-6-(5- naphthoate 4-aminobutyrate methylmalonate- -dihydrolipoyl-L-lysine pyruvate ammonium [+ 2 isozymes] acyltransferase: desulfurase: acyltransferase: reductase: reductase: reductase: reductase: reductase: [+ 3 isozymes] oxaloacetate sulfate RS07830 sulfate D-ribulose prenyltransferase: synthetase: L-lysine asp undecaprenyldiphospho-murG even numbered 6-phosphate a [glutamineBUE88_RS00980 synthase: dihydropteroate cofactor SAH component: BUE88_RS01125 BUE88_RS08345 butan-1-al sulfanyl-[disordered- 5-phosphate phosphoribosylamino) synthase: pyridoxal 5'-phosphate biosynthesis I + BUE88_RS04185 aminotransferase, semialdehyde N-acetyl-(N-acetyl-β-D- diphosphate AMP straight chain deacetylase: nagA a [ThiIBUE88_RS05875 sulfur- synthetase]-O BUE88_RS09060 a (3R)-3-BUE88_RS14775 a (3R)-3-BUE88_RS14775 a (3R)-3-BUE88_RS14775 a (3R,9Z)-3-BUE88_RS14775 a cis-delta9-3-BUE88_RS14775 decarboxylase: NADP BUE88_RS13780 an L-glutamyl- rnpA aspartate UDP (4Z,7Z,10Z,13Z,16Z)- 3-oxohexanoyl- form scaffold bifunctional uracil reductase: BUE88_RS05525 mitochondrial: gabT dehydrogenase carbamoyl- acetyl-CoA D-galactosamine 4 ligK 3,4- geranyl Gln a tRNA precursor aminotransferase: glucosaminyl)muramoyl- 2,3,4-saturated docosapentaenoyl-CoA acetate ala carrier protein]-S- -(5'-adenylyl) CoA canavaninosuccinate hydroxyhexacosanoyl- hydroxydodecanoyl- hydroxypimeloyl- hydroxyhexadec- hydroxyC28:1- isoleucine-- [tRNA ] phosphate 6-phosphate protein] complex folylpolyglutamate BUE88_RS03370 1,4-dihydroxy-2- D-erythrose diphosphate ile a tRNA precursor with (CoA acylating) L-alanyl-γ-D-glutamyl-L- fatty acyl CoA sulfanyl-L-cysteine -L-tyrosine [acp] [acp] [acp] methyl ester 9-enoyl-[acp] [acp] pyruvate 2+ 2+ cysteine dihydroxy-2- 5-amino-6-(5- tRNA ligase: with a 5' extension BUE88_RS09570 Zn RS12455 Zn synthase/ 4-phosphate Asp-tRNA(Asn) a short 3' extension : mmsA synthase lysyl-D-alanyl-D-alanine desulfurase: butanone-4- naphthoyl-CoA (S)-3-amino-2- [+ 3 isozymes] dihydrofolate phospho-D- BUE88_RS17285 an L-isoleucyl- /Glu-tRNA(Gln) large BUE88_RS05875 phosphate methylpropanoate aminomethyltransferase: oxaloacetate ribitylamino)uracil S-ribosyl-L- [tRNA Ile ] ribonuclease: argininosuccinate subunit: carB synthase: amidotransferase gcvT synthase: Ile ribonuclease PH: ribonuclease D: hydrogencarbonate a 2-methyl a 1-acyl-sn 1518 a 3- a (7Z)-3- a 1-acyl-sn cysteine BUE88_RS17290 NAD biosynthesis homocysteine a tRNA subunit GatC: rnpA lyase: argH a nascent peptidoglycan ditrans,octacis- adenine / 5-cis, 7-trans-3-oxo- 3-oxo- 1-[18-hydroxyoleyl]- BUE88_RS16550 BUE88_RS01130 gcv system: gcvP carbamoyl- an acyl-[acyl- a 3-oxohexadecanoyl- a 3-oxohexanoyl- butan-1-ol desulfurase: ribB 4-phospho- with (L-alanyl-γ-D- undecaprenyldiphospho- branched 2,3,4- -glycerol 3- 1519 tetradecadienoyl-CoA palmitoyl-CoA 2-lyso-phosphatidate oxodocosanoyl- oxohexacos- -glycerol 3- 7,8-dihydrofolate I (from aspartate) 2-carboxy-1,4- BUE88_RS16595 L-arginino- phosphate lipid II (meso carrier protein] adenine in 16S rRNA [acp] [acp] dIDP BUE88_RS03730 1-deoxy-L- D-erythronate L-ornithine glutamyl-meso-2,6- N-acetyl-(N- saturated fatty acid phosphate 16S rRNA acetyl-CoA C- acetyl-CoA C- 1-acyl-sn-glycerol- 3-oxoacyl-ACP [acp] 3-oxoacyl-ACP 3-oxoacyl-ACP 7-enoyl-[acp]3-oxoacyl-ACP phosphate NAD(P)- a [cysteine monoglutamate naphthoquinol [+ 2 isozymes] succinate synthase diaminopimelate long-chain fatty 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- glycero-tetrulose acyltransferase: acyltransferase: 3-phosphate dependent alcohol nucleoside- desulfurase]-(S- ARP diaminopimeloyl- acetylglucosaminyl) acid--CoA ligase: 3-phosphate (adenine(1518)-N(6)/ reductase FabG: reductase FabG: reductase FabG: reductase FabG: 3-phosphate 4-phosphate asp an L-glutaminyl- argininosuccinate small subunit: containing) diphosphate D-alanyl-D-alanine) muramoyl-L-alanyl-γ- BUE88_RS18710 acyltransferase: adenine(1519)-N(6))- BUE88_RS08345 BUE88_RS01125 acyltransferase: BUE88_RS02435 BUE88_RS02435 BUE88_RS02435 BUE88_RS02435 dehydrogenase: sulfanyl) -[disordered- leucine-- Gln BUE88_RS02830 peptidoglycan acyltransferase: 2 L-aspartate L-homocysteine leu [tRNA ] an uncharged tRNA synthase: BUE88_RS04005 BUE88_RS01710 kinase: form scaffold pentapeptide glycosyltransferase: D-isoglutaminyl-N-(β- [+ 2 isozymes] BUE88_RS14730 dimethyltransferase acetyl-CoA C- acetyl-CoA C- 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP BUE88_RS04005 6,7-dimethyl-8- (3R)-3-hydroxy-2-oxo- tRNA ligase: Aromatic Compound Degradation BUE88_RS08735 a nascent peptidoglycan a 2-methyl BUE88_RS17300 oxidase: nadB carbamoyl D-asparaginyl)-L-lysyl-peptidoglycan RsmA: acyltransferase: acyltransferase: [+ 2 isozymes] [+ 3 isozymes] protein] complex 4 phosphooxybutanoate BUE88_RS00255 withBUE88_RS18770 (L-alanyl-γ-D- branched [+ 2 aisozymes] 1,2-diacyl- 1-[18-hydroxyoeoyl]-2- reductase: reductase: reductase: reductase: a 1-acyl-2-[+ 2 isozymes] a 7,8-dihydrofolate ribityllumazine 2-iminosuccinate cystathionine 10 an L-leucyl- argininosuccinate N -formyl-tetrahydrofolate biosynthesis phosphate di-trans,octa-cis di-trans,octa-cisD-alanyl-D-alanineglycosyltransferase: AMP diphosphate 6 BUE88_RS073201518 BUE88_RS01125 BUE88_RS08345 butan-1-al dITP Leu 5-oxo-L-proline metabolism glutamyl-meso-2,6- a peptidoglycan 2,3,4-saturated acyl-carrier protein sn-glycerol N -dimethyladenine [18-hydroxy-lioleoyl]-sn a (3R)-3-BUE88_RS14775 a (3R)-3-BUE88_RS14775 a (3R)-3-BUE88_RS14775 a (3R,7Z)-3-BUE88_RS14775 palmitoyl-sn synthase: phosphoserine beta-synthase: [tRNA ] protocatechuate synthase: ornithine -undecaprenyl (3Z,5E)-dodeca- Leu gentisate degradation I atrazine degradation I (aerobic) -undecaprenyl BUE88_RS18770 6 1519 acetyl-CoA myristoyl-CoA acetyl-CoA dihydrofolate BUE88_RS05735 quinolinate transaminase: BUE88_RS05265 a tRNA catechol catechol degradation to diaminopimeloyl- dimer (E. faeciums) fatty acyl-CoA 3-phosphate /N -dimethyladenine -glycerol 3-phosphate hydroxyhexadecanoyl- hydroxydocosanoyl- hydroxyhexanoyl- hydroxyhexacos- -glycerol 3- an N-terminal degradation II (ortho- BUE88_RS09060 carbamoyltransferase: diphosphate diphosphate 3,5-dienoyl-CoA reductase: synthase NadA: Amine and Polyamine degradation to 2- 2-oxopent-4-enoate I D-alanyl-D-alanine) in 16S rRNA a [cysteine desulfurase]- BUE88_RS09170 a tetrahydrofolate an N-terminal L- cleavage pathway) argF [acp] [acp] [acp] 7-enoyl-[acp] phosphate Biosynthesis L-glutaminyl- BUE88_RS12130 6,7-dimethyl-8-(1- BUE88_RS05890 L-cystathionine oxopent-4-enoate II gentisate atrazine pentapeptide [scaffold protein- 4-phosphooxy- Glycolysis [protein] glutamyl-[protein] [+ 3 isozymes] protocatechuate catechol (2Fe-2S)] complex D-ribityl)lumazine L-threonine catechol triazine hydrolase: quinolinate spermine biosynthesis catechol 2,3- L-citrulline D-glyceraldehyde catechol 2,3- BUE88_RS06830 a tetrahydrofolate riboflavin synthase pyruvate a [2-oxoglutarate dehydrogenase E2 a 7,8-dihydro-8- salicyl-6-hydroxy-2- 3-oxo- 4-trans-3-oxo- a [release factor]- a 3- a (7Z)-3-oxo- a (7Z)-3- a 1-acyl-sn 3-phosphate val glycolysis III (from glucose) dioxygenase: 1-myristoylglycerol octanoyl-CoA acetyl-CoA a 3-oxotetracosanoyl- phytol subunit alpha: nicotinate- valine--tRNA ligase: 3-carboxy-cis dioxygenase: 3-maleylpyruvate hydroxyatrazine 6 a myristoyl-[acp] (6Z,9Z,12Z,15Z,18Z,21Z) undecenoyl-CoA oxodocosanoyl- hexadec-7- oxotetradec- -glycerol 3- BUE88_RS08365 protein] N -dihydrolipoyl-L-lysine oxoguanine in DNA 3-phosphate cyclohexene-on-oyl L-glutamine [acp] IDP BUE88_RS05745 nucleotide 1-deoxy-D- BUE88_RS17240 an L-valyl- SAM a [protein] with ,cis-muconate BUE88_RS08365 multifunctional oxoglutarate bifunctional DNA- carboxylesterase/ -tetracosahexaenoyl-CoA acetyl-CoA C- acetyl-CoA C- peptide chain 3-oxoacyl-ACP [acp] 3-oxoacyl-ACP enoyl-[acp]3-oxoacyl-ACP 7-enoyl-[acp]3-oxoacyl-ACP phosphate NAD(P)- a [co-chaperone]- D-glucopyranose hydroxyatrazine HMS 1-acyl-sn-glycerol- acetyl-CoA C- 1-acyl-sn-glycerol- diphosphorylase (2S)-2-amino-3-oxo-4- cys Val an N-terminal 5- HMS maleylpyruvate decarboxylase/oxoglutarate formamidopyrimidine lipase family acyltransferase: acyltransferase: release factor dependent alcohol nucleoside- [scaffold protein- xylulose-5- [tRNA ] 3-phosphate acyltransferase: reductase FabG: reductase FabG: reductase: reductase: 3-phosphate riboflavin phosphooxybutanoate Val ethylaminohydrolase: diphosphate (carboxylating): phosphate a tRNA oxo-L-proline isomerase dehydrogenase thiamine glycosylase/ protein: BUE88_RS08345 BUE88_RS01125 N(5)-glutamine BUE88_RS02435 BUE88_RS02435 BUE88_RS14775 BUE88_RS14775 dehydrogenase: (2Fe-2S)] complex dihydrofolate reductase: glucokinase: γ-L-glutamyl BUE88_RS06830 acyltransferase: BUE88_RS08345 acyltransferase: BUE88_RS05880 superpathway of heme family mycothiol- pyrophosphate-binding DNA-(apurinic or BUE88_RS08135 methyltransferase: BUE88_RS01710 kinase: thiamine salvage II bifunctional synthase: BUE88_RS12130 spermidine dAdoMet BUE88_RS18715 5-phosphate glutathione Fatty Acid and BUE88_RS04005 acetyl-CoA C- acetyl-CoA C- 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP BUE88_RS14730 b biosynthesis from pyroglutamyl- (2-carboxy- dependent acetyl-CoA C- BUE88_RS17300 dxs N-isopropylammelide 2-oxopent- subunit/dihydrolipoyllysine- apyrimidinic site) lyase: [+ 4 isozymes] acyltransferase: acyltransferase: prmC [+ 3 isozymes] riboflavin kinase/ [+ 3 isozymes] D-glucopyranose 2,5-dihydro- formate Lipid Degradation [+ 2 isozymes] 6-hydroxy-2- 5 reductase: reductase: reductase FabG: reductase FabG: a 1,2-diacyl-[+ 2 isozymes] NaMN uroporphyrinogen-III spermine synthase: peptidase (2Z,4E)-2- enzyme: 4-enoate acyltransferase: a [release factor]-N 4-amino-2-methyl-5- FAD synthetase: 1-deoxy-D- 3-amino-1- serine residue succinyltransferase BUE88_RS03950 dimyristoyl BUE88_RS01125 BUE88_RS08345 BUE88_RS14775 BUE88_RS14775 BUE88_RS02435 BUE88_RS02435 phytenal ITP a [chaperone-ATP]- BUE88_RS10300 6-phosphate I: pcp 5-oxofuran- hydroxyhexa- BUE88_RS07405 an apurinic site 7,8-dihydro- acyl-carrier protein salicyl alcohol cyclohexen- BUE88_RS01125 2-trans- 3-oxodecanoyl- -methyl-L-glutamine a (3R)-3- a (3R)-3- a (3R,7Z)-3- a (3R,7Z)-3- sn-glycerol BUE88_RS02940 nicotinate-nucleotide uroporphyrinogen-III xylulose 5- hydroxyacetone a 7,8-dihydrofolate hydroxymethyltransferase:gcv system:a 5-methyltetrahydrofolate gcvP fatty acid β-oxidation I subunit: kgd phosphatidate docosahexaenoyl- acetyl-CoA [co-chaperone]- pyrimidinemethanol alanine-- 2-yl)-acetate 2,4-dienedioate one-carboxylate acetyl-CoA hydroxytetracosanoyl- hydroxydocosanoyl- hydroxy-hexadec- hydroxytetradec- 3-phosphate uroporphyrinogen 1-phosphate BUE88_RS09515 ala S-methyl-5'- glucose-6- a [2-oxoglutarate dehydrogenase E2 within DNA 8-oxoguanine nonenoyl-CoA CoA bifunctional adenylyltransferase: phosphate tRNA ligase: spermine carboxymuconolactone 3-fumarylpyruvate CoA [scaffold protein- FMN thioadenosine phosphate protein] N 6 -S-succinyldihydrolipoyl-L-lysine [acp] [acp] 7-enoyl-[acp] 7-enoyl-[acp] BUE88_RS17365 decarboxylase: 5-oxo-L-proline decarboxylase: cyanurate isopropylamine a (3Z)-alk-3- (2Fe-2S)] complex hydroxymethylpyrimidine thymidylate synthase: BUE88_RS02910 an L-alanyl- BUE88_RS11955 isomerase: enoyl-CoA kinase/ nicotinate adenine Ala BUE88_RS11015 bifunctional BUE88_RS19115 [tRNA ] BUE88_RS07650 coproporphyrinogen III Ala (4,5-dihydro- (3E)-2-oxohex- a 3,5,7,9,11,13,15- a (5Z)-3- phosphomethylpyrimidine riboflavin kinase/ dinucleotide a tRNA ∆ 3 -cis-∆ 2 -trans- 3-oxo-(5Z)- (2R,3S)-3- (S)-4-amino-5- a [protein]-L- thymidylate synthase: glucose-6- 5-oxofuran- seleno-L- 1-myristoylglycerol 1-palmitoylglycerol laurate a (6S)-5- a uracil in DNA a 3-oxotetradecanoyl- a 3-oxodecanoyl- kinase: thiD pyridoxine heme b biosynthesis 3-enedioate a palmitoleoyl-[acp] a myristoyl-[acp] Glu tetradecenoyl-CoA hepta-oxo- isopropylmalate oxotetracos- FAD synthetase: NAD+ synthetase, BUE88_RS17630 bifunctional fumarate pyruvate enoyl-CoA homocysteine 3-phosphate 3-phosphate formyltetrahydrofolate [acp] [acp] IMP oxopentanoate methionine I (aerobic) a (6S)-5-formyltetrahydrofolate Aromatic Compound phosphate 2-yl)-acetate long-chain fatty uracil-DNA acetyl-CoA C- hexadecanoyl-[PKS-acp] 3-isopropylmalate 5-enoyl-[acp] glutamate-1- peptide- a [chaperone- BUE88_RS02940 glutamine NAD(+) synthase: 5'-phosphate isomerase: 5-methyltetrahydropteroyltriglutamate- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- aldo/keto 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP an [2Fe-2S] methylenetetrahydrofolate Biosynthesis isomerase: bifunctional bifunctional ADP]-[disordered- HMP-P Glu - homocysteine S- acid--CoA ligase: glycosylase: acyltransferase: reductase: reductase FabG: dehydratase reductase FabG: reductase FabG: semialdehyde- methionine dependent: BUE88_RS09035 pyridoxine 5'- dehydrogenase/ 5-formyltetrahydrofolate BUE88_RS01120 3-phosphate 3-phosphate folylpolyglutamate cluster protein 5-(2-hydroxyethyl) FAD uroporphyrinogen-III BUE88_RS02515 BUE88_RS18710 BUE88_RS15120 BUE88_RS08345 large subunit: leuC metallophosphatase/ 2,1- (R)-S-oxide form scaffold BUE88_RS09035 phosphate oxidase: methyltransferase: BUE88_RS12425 acyltransferase: acyltransferase: BUE88_RS08260 BUE88_RS02435 BUE88_RS02435 BUE88_RS02435 bifunctional protoporphyrinogen IX uroporphyrinogen methenyltetrahydrofolate cyclo-ligase: chorismate biosynthesis I 2-oxopent- synthase/ 5'-nucleotidase: protein] complex -4-methylthiazole asn BUE88_RS04005 BUE88_RS04005 [+ 2 isozymes] uracil-DNA acetyl-CoA C- 3-isopropylmalate aminomutase: reductase: hydroxymethylpyrimidine BUE88_RS06880 cyclohydrolase: BUE88_RS08850 F6P 4-enoate 5-methyltetrahydropteroyltriglutamate- dihydrofolate 9-hydroxy-3,5,7,11,13,15-[+ 27 isozymes] 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP hydroxyethylthiazole NAD + decarboxylase: 3-oxoadipate BUE88_RS06935 hemL msrB BUE88_RS09510 D-erythrose - homocysteine methyltransferase: [+ 2 isozymes] [+ 2 isozymes] synthase: glycosylase: acyltransferase: reductase: dehydratase reductase: reductase: a protein-L- kinase/ BUE88_RS11955 an L-asparaginyl- a (2E)-2- 1-myristoyl-2- 1-palmitoyl- AMP diphosphate lauroyl-CoA hexaoxohexadecanoyl- kinase: PLP a 5,10-methylenetetrahydrofolate a 5,10-methenyltetrahydrofolate 4-phosphate 6-phosphofructokinase: long-chain fatty BUE88_RS15345 BUE88_RS03500 BUE88_RS01125 BUE88_RS14775 small subunit: leuD BUE88_RS14775 BUE88_RS14775 inosine 5-aminolevulinate phosphomethylpyrimidine coproporphyrinogen III [tRNA Asn ] enoyl-CoA enoyl-CoA acyl-carrier protein palmitoleoyl acyl-carrier protein 2-myristoyl BUE88_RS17290 [PKS-acp] a (3R)-3- a (3R)-3- a (3R,5Z)-3- methionine- BUE88_RS18600 6 37 an apyrimidinic (3Z)-dodec- (2S)-2- Asn BUE88_RS12030 N -L-threonylcarbamoyladenosine a 2,3,4-saturated acid--CoA ligase: a (6S)-5- uracil acetyl-CoA an [Fe-S cluster a [disordered- kinase: thiD heme b biosynthesis tRNA 3-deoxy-7- coenzyme A hydratase: 3-hydroxybutyryl- a 2,3,4- SeMet phosphatidate phosphatidate hydroxytetradecanoyl- hydroxydecanoyl- hydroxytetracos- (R)-S-oxide 4-methyl-5-(2- protoporphyrin IX bifunctional BUE88_RS07510 acyl-CoA formyltetrahydrofolate site in DNA 3-enoyl-CoA isopropylmalate phosphoheptulonate β-D-fructose 1,6- -modified tRNA biosynthesis fatty acid BUE88_RS01120 biosynthesis form [Fe-S] cluster phosphooxyethyl) II (anaerobic) CoA epimerase: saturated (3R)-3- [acp] [acp] 5-enoyl-[acp] HMP-PP methylenetetrahydrofolate [+ 2 isozymes] dehydrogenase: chaperone]-ATP scaffold protein] heme a biosynthesis synthase: bisphosphate BUE88_RS01120 hydroxyacyl-CoA thiazole deferrochelatase/ dehydrogenase/ BUE88_RS15605 uroporphyrinogen-III BUE88_RS18725 thr peroxidase EfeB: trans, trans-farnesyl methenyltetrahydrofolate a 2,3,4- 1-cis- 1402 2251 1-cis- a (3R,5Z)-3- an (11Z)-3- (3R,5S)-3- uroporphyrinogen protoporphyrinogen IX 3-deoxy- threonylcarbamoyl- [+ 6 isozymes] a ring-opened 7- 1-palmitoylglycerol 3-oxo-(7Z)- 3-oxo- a cytidine guanosine a [protein]- thiamine BUE88_RS06940 S-adenosyl-L-methionine cycle I aspartate-- fructose- a 2,3,4-saturated oleate decanoyl-CoA acetyl-CoA an alcohol ferroheme b diphosphate cyclohydrolase: saturated (3S)-3- methylguanine in DNA a palmitoleoyl-[acp] vaccenoylglycerol- a palmitoyl-[acp] hexadecenoyl-CoA myristoyl-CoA in 16S rRNA vaccenoylglycerol- hydroxy-tetradec- oxooctadec- L-histidine hydroxy-1- decarboxylase: asp D-arabino- bisphosphate AMP synthase: fatty acyl CoA 3-phosphate in 23S rRNA phosphate protoheme IX ferrochelatase: biosynthesis BUE88_RS09510 tRNA(Asn) ligase: hydroxyacyl-CoA bifunctional DNA- 3-phosphate long-chain fatty acetyl-CoA C- acetyl-CoA C- acetyl-CoA C- 16S rRNA 23S rRNA 3-phosphate 5-enoyl-[acp] 11-enoyl-[acp] NAD(P)- histidine kinase: pyrroline-5- BUE88_RS11955 heptulosonate BUE88_RS03140 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 3-oxoacyl-ACP 3-oxoacyl-ACP synthase: thiE BUE88_RS05585 aldolase: acid--CoA ligase: acyltransferase: acyltransferase: acyltransferase: BUE88_RS07985 farnesyltransferase: BUE88_RS11985 an L-aspartyl- L-threonylcarbamoyladenylate 3-hydroxyacyl-CoA formamidopyrimidine 3-phosphate 3-phosphate (cytidine(1402)-2'-O) (guanosine(2251) reductase: reductase FabG: dependent alcohol carboxylatepyrroline-5- coproporphyrinogen III IPP SAM an N 10 -formyltetrahydrofolate 7-phosphate BUE88_RS10730 Secondary Metabolite Degradation acetyl-CoA C- 3-phosphate BUE88_RS02500 [tRNA asp ] dehydrogenase: glycosylase/ BUE88_RS18710 BUE88_RS01125 BUE88_RS01125 BUE88_RS01125 -methyltransferase: -2'-O)- dehydrogenase: histidine kinase: carboxylate acyltransferase: acyltransferase: acyltransferase: acyltransferase: BUE88_RS14775 BUE88_RS02435 ferroheme o ferroheme b isopentenyl- asp 3-dehydroquinate 6 protoporphyrin IX tRNA class II fructose- N -L- BUE88_RS01120 DNA-(apurinic or BUE88_RS04005 BUE88_RS04005 [+ 2 isozymes] acetyl-CoA C- acetyl-CoA C- acetyl-CoA C- rsmI methyltransferase BUE88_RS12830 BUE88_RS03535 reductase: thiamine phosphate diphosphate synthase: BUE88_RS08345 a 2'-O- BUE88_RS04005 3-oxoacyl-ACP 3-oxoacyl-ACP a [protein]- bisphosphate threonylcarbamoyladenine anhydromuropeptides recycling I apyrimidinic site) lyase: acyltransferase: acyltransferase: acyltransferase: 1402 RlmB: [+ 3 isozymes] proC BUE88_RS02885 L-threitol degradation a 2,3,4-saturated a 2,3,4-saturated [+ 1-cis-vaccenoyl-2 isozymes] [+ 2 isozymes] methylcytidine 1,2-dicis-[+ 2 isozymes] reductase FabG: reductase: N-phospho- trans-4-hydroxy- heme A synthase: Delta-isomerase: deferrochelatase/ methionine aldolase: synthase: tsaD acetyl-CoA C- BUE88_RS03950 diphosphate AMP oleoyl-CoA thiamine- dipalmitoyl BUE88_RS08345 BUE88_RS08345 BUE88_RS08345 in 16S rRNA BUE88_RS09300 BUE88_RS02435 BUE88_RS14775 an aldehyde L-histidine BUE88_RS13750 adenosyltransferase: 6 GlcNAc-1,6- fatty acyl CoA acyltransferase: 3-oxoacyl-CoA 2,6-diamino-4- acyl-carrier protein 2-palmitoleoyl acyl-carrier protein 2-O- vaccenoyl- a (5Z)-3-oxo- a (3R,11Z)-3- L-proline protoporphyrinogen IX BUE88_RS02495 peroxidase EfeB: BUE88_RS16040 an N -L- an apurinic site phosphatidate (5Z)- 3-oxododecanoyl- phosphate 3-dehydroquinate hydroxy-5-(N-methyl) acetyl-CoA acetyl-CoA lauroyl-CoA methylguanosine 2251 DMAPP BUE88_RS06940 BUE88_RS02805 threonylcarbamoyladenine 37 anhMurNAc- L-threitol BUE88_RS01125 phosphatidate tetradecenoyl-CoA CoA phosphatidate tetradec-5- hydroxyoctadec- kinase: thiL menaquinol-11 biosynthesis within DNA ferroheme i tyrosine-- L-Ala-γ-D-Glu- erythritol/L-threitol formamidopyrimidine in 23S rRNA enoyl-[acp] 11-enoyl-[acp] ferrochelatase: tyr type II 3- in tRNA prenyltransferase: all-trans- tRNA ligase: triosephosphate DAP-D-Ala dehydrogenase: thiamine diphosphate BUE88_RS11985 2-carboxy-1,4- dehydroquinate heme A synthase: BUE88_RS13780 met SAH undecaprenyl BUE88_RS08720 an L-tyrosyl- isomerase: BUE88_RS06250 dehydratase: aroQ a 3-methyl- 1402 naphthoquinol Tyr a single 3-oxo-(9Z)- 3-oxo-(5Z)- 4-(cytidine 5'- a (6Z)-3- a [lipoyl-carrier 6-O-trans- BUE88_RS02495 ferroheme b diphosphate [tRNA ] BUE88_RS11770 L-erythrulose 1-palmitoylglycerol a nucleoside hexanoyl-CoA acetyl-CoA a cytidine 1-myristoylglycerol a 3-oxooctanoyl- protoporphyrin IX 1,4-dihydroxy- a palmitoleoyl-[acp] branched 2,3,4- a ribonucleic acid diphospho)-2-C- oxooctadec- protein]-N 6 -[(R) lys methoxy-mycolyl- geranyl a tRNA Tyr 3-dehydroshikimate acetyl-CoA stranded DNA 3-phosphate triphosphate octadecenoyl-CoA dodecenoyl-CoA in 16S rRNA 3-phosphate [acp] 2-naphthoate [+ 2 isozymes]D-glyceraldehyde saturated fatty acid acetyl-CoA C- acetyl-CoA C- acetyl-CoA C- hydroxyferroheme i diphosphate 5-methyltetrahydropteroyltriglutamate- DHAP L-erythrulose exodeoxyribonuclease 1-acyl-sn-glycerol- long-chain fatty DNA-directed 16S rRNA methyl-D-erythritol4-(cytidine 5'- 1-acyl-sn-glycerol- 3-oxoacyl-ACP 6-enoyl-[acp]3-oxoacyl-ACP -dihydrolipoyl]- trehalose 6- deferrochelatase/ polyprenyltransferase: Pentose Phosphate Pathways N-acetyl-β-D- L-alanyl-γ-D- L-lysine 6- - homocysteine S- 3-phosphate 4-kinase: VII small subunit: acyltransferase: acyltransferase: acyltransferase: (cytosine(1402)-N(4) L-lysine phosphate peroxidase EfeB: shikimate shikimate 5- glucosamine-1,6- glutamyl-meso-2,6- 3-phosphate acid--CoA ligase: RNA polymerase diphospho)- 3-phosphate reductase FabG: reductase FabG: dihydrolipoyl trehalose- folate polyglutamylation prenyltransferase: BUE88_RS05515 glyceraldehyde- BUE88_RS06260 BUE88_RS16010 BUE88_RS01125 BUE88_RS01125 BUE88_RS08345 )-methyltransferase: monooxygenase: methyltransferase: BUE88_RS12425 dehydrogenase: dehydrogenase: acyltransferase: BUE88_RS18710 subunit beta: 2-C-methyl-D- acyltransferase: BUE88_RS02435 BUE88_RS02435 dehydrogenase: phosphatase: BUE88_RS06940 thioredoxin BUE88_RS13780 DMKH2-11 anhydro-N-acetyl- diaminopimeloyl- BUE88_RS09740 3-phosphate pentose phosphate pathway (non-oxidative branch) acetyl-CoA C- acetyl-CoA C- acetyl-CoA C- 4 BUE88_RS18760 5-methyltetrahydropteroyltriglutamate- BUE88_RS10745 BUE88_RS10745 β-D-muramate D-alanine L-erythrulose exodeoxyribonuclease BUE88_RS04005 [+ 2 isozymes] BUE88_RS09430 an N - erythritol kinase: BUE88_RS04005 3-oxoacyl-ACP 3-oxoacyl-ACP lpdA otsB ferrochelatase: pathway tryptophan- a 3-methyl- a [lipoyl-carrier N 6 -hydroxy- trehalose- a tetrahydrofolate (2E,6E)-farnesyl - homocysteine methyltransferase: demethylmenaquinone a tRNA Trp dehydrogenase: 4-phosphate VII large subunit: acyltransferase: acyltransferase: acyltransferase: 1402 BUE88_RS07260 beta-N- [+ 21-palmitoyl-2- isozymes] branched [+ 4 isozymes] methylcytidine 2-phospho-4-(cytidine 1-myristoyl-2-[+ 2 isozymes] reductase: reductase: 6 BUE88_RS11985 ferroheme a S-ribosyl-L- -tRNA gap D-ribulose Detoxification diphosphate AMP protein]-N - L-lysine trans-methoxy- diphosphate BUE88_RS15345 L-homocysteine methyltransferase: shikimate BUE88_RS16020 BUE88_RS08345 BUE88_RS08345 BUE88_RS01125 in 16S rRNA BUE88_RS14775 BUE88_RS14775 an oxidized ligase: trpS 5-phosphate acetylhexosaminidase: acyl-carrier protein palmitoleoyl 2,3,4-saturated a ribonucleic acid (7Z)- 3-oxooctanoyl- (3Z)-dec-3- 5'-diphospho)-2-C- palmitoleoyl a (3R)-3- a (3R,6Z)-3- lipoyl-L-lysine mono-mycolate homocysteine BUE88_RS05490 an L-tryptophanyl- a single-stranded a ribonucleoside ferroheme b thioredoxin BUE88_RS14080 phosphatidate fatty acyl-CoA acetyl-CoA acetyl-CoA methyl-D-erythritol phosphatidate hydroxyoctanoyl- hydroxyoctadec- serine bifunctional geranylgeranyl [tRNA Trp ] shikimate kinase: 13-DPG L-alanyl-γ-D- arsenate oligodeoxyribonucleotide 5'-monophosphate hexadecenoyl-CoA CoA enoyl-CoA reactive oxygen species degradation oxidized GTP and [acp] 6-enoyl-[acp] hydroxymethyltransferase: folylpolyglutamate diphosphate menaquinol-11 trp BUE88_RS02890 ribulose- ribose-5-phosphate 1,6-anhydro-N- glutamyl-meso- D-erythrulose detoxification dGTP detoxification BUE88_RS09515 synthase/ 10 biosynthesis acetyl-β-muramate diaminopimelate 4-phosphate an N - thiamine diphosphate phosphoglycerate phosphate 3- isomerase: II (glutaredoxin) thioredoxin- menaquinol-7 biosynthesis shikimate 3- dihydrofolate formyltetrahydrofolate glutathione (2E,6E)-farnesyl epimerase: BUE88_RS06265 superoxide a DNA containing an odd numbered (9Z,12Z)-15,16- 527 1-cis- a 1-alkyl-sn biosynthesis II (Bacillus) kinase: pgk arsenate 3-oxo-(9Z)- a damaged a guanine a 5,10- synthase: disulfide diphosphate thiamine diphosphate demethylmenaquinol- phosphate a cis- 1-palmitoylglycerol an α L-rhamnoside a cis-delta15-3- D-mannitol biosynthesis rpe [+ 2 isozymes] dGTP GTP an apurinic/ straight chain hexadecenoyl-CoA a type IV prepilin epoxyoctadeca- vaccenoylglycerol- -glycerol 3- cys cys bifunctional reductase: 2-carboxy-1,4- geranylgeranyl 2-(2-carboxy-4- biosynthesis I (E. coli) 6 biosynthesis I 3-phospho- arsenate vaccenoyl-[acp] 3-phosphate DNA pyrimidine in 16S rRNA oxo-C34:1-[acp] methylenetetrahydrofolate BUE88_RS17290 3-phosphoshikimate 1- superoxide dismutase: apyrimidinic site 2,3,4-saturated alpha-L- acetyl-CoA C- 9,12-dienoate 16S rRNA 3-phosphate phosphate NAD(P)- folylpolyglutamate pyrophosphate HMP-PP methylthiazol-5- threonine-- D-glycerate N-acetyl-D- D-erythrose reductase ArsC: 1-acyl-sn-glycerol- prepilin peptidase: bifunctional DNA- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 3-oxoacyl-ACP trxB naphthoquinol 2-[(2R,5Z)-2-carboxy- all-trans- thr carboxyvinyltransferase: D-xylulose BUE88_RS05690 bifunctional DNA- long-chain fatty rhamnosidase: cystathionine cystathionine bifunctional cys Glu 1,4-dihydroxy- menaquinol-8 biosynthesis tRNA ligase: D-ribose 5- muramate 6- N-acetylglucosamine fatty acid acyltransferase: BUE88_RS10215 formamidopyrimidine epoxide hydrolase: (guanine(527)-N(7) reductase FabG: dependent alcohol synthase/ [+ 2 isozymes] synthase: yl)ethylthiamine phosphate 2-carboxy-1,4- phosphoglycerate 4-phosphate BUE88_RS15040 formamidopyrimidine 3-phosphate 3-phosphate 3-phosphate folylpolyglutamate 2-naphthoate HMP-PP 4-methylthiazol-5(2H)- hexaprenyl aroA 5-phosphate phosphate degradation I acid--CoA ligase: BUE88_RS06340 BUE88_RS01125 glycosylase/ )-methyltransferase dehydrogenase: beta-synthase: beta-synthase: a tetrahydrofolate dihydrofolate glutamate-- BUE88_RS13755 phosphate naphthoquinol BUE88_RS01965 an L-threonyl- phosphate 8-oxo-dGTP 8-oxo-GTP glycosylase/ acyltransferase: prepilin peptidase: BUE88_RS03725 acyltransferase: acyltransferase: BUE88_RS02435 ylidene]ethylthiamine phosphate phosphate diphosphate mutase: arsenate hydrogen peroxide BUE88_RS18710 a non BUE88_RS01710 BUE88_RS05265 BUE88_RS05265 arsenite RS15035 arsenite synthase/ cysteine ligase: polyprenyltransferase: 1,4-dihydroxy- Thr 3-phosphoshikimate 1- N-acetylmuramic acetyl-CoA C- DNA-(apurinic or RsmG: synthase: geranylgeranyl synthase: thiE demethylmenaquinol-8 [tRNA ] BUE88_RS09345 N-acetyl-D- reductase ArsC: DNA-(apurinic or an odd numbered BUE88_RS04005 rhamnosylated β-L- BUE88_RS19165 (9Z,12Z)-15,16- BUE88_RS04005 BUE88_RS14730 3-oxoacyl-ACP synthase: thiE Thr transketolase: dihydrofolate BUE88_RS03910 BUE88_RS05515 thiamine phosphate 2-naphthoate demethylmenaquinone carboxyvinyltransferase: acid 6- 8-oxo-dGTP [+ 2 isozymes] acyltransferase: a cleaved type apyrimidinic site) lyase: 7 BUE88_RS11415 [+ 3 isozymes] BUE88_RS17290 γ-L-glutamyl- a reduced pyrophosphate thiamine phosphate a tRNA glucosamine BUE88_RS15455 apyrimidinic site) lyase: straight chain [+ 21-palmitoyl-2- isozymes] rhamnosyl rhamnopyranose a peptide dihydroxyoctadeca- an N - 1-cis-vaccenoyl-[+ 2 isozymes] a 2-acyl-1-alkyl-[+ 2 isozymes] reductase: lanthionine ser synthase: demethylmenaquinol-7 polyprenyltransferase: aroA 2-phospho- BUE88_RS02505 diphosphatase: aldehydo- 10 methyltransferase: phosphate catalase: diphosphate AMP BUE88_RS08345 IV prepilin BUE88_RS03950 9,12-dienoate 527 an N - L-cysteine thioredoxin synthase: 6-phosphateN-acetylglucosamine- erythritol arsenite BUE88_RS03950 2,3,4-saturated acyl-carrier protein cis-vaccenoyl acceptor methylguanine 2-palmitoleoyl sn-glycerol a cis-delta15-3-BUE88_RS14775 D-mannose BUE88_RS17290 thiamine- BUE88_RS05515 5-enolpyruvoyl- D-glycerate etherase: murQ BUE88_RS17480 (7Z)- an apyrimidinic a reduced BUE88_RS05490 6-phosphate BUE88_RS14475 a 3'-terminal a 5'-phospho- acetyl-CoA in 16S rRNA formyltetrahydrofolate demethylmenaquinone BUE88_RS18745 thiamine-phosphate demethylmenaquinol-6 shikimate 3- D-sedoheptulose D-glyceraldehyde degradation II fatty acyl CoA phosphatidate tetradecenoyl-CoA site in DNA phosphatidate 3-phosphate hydroxyC34:1- H O c-type phosphate menaquinol-8 phosphopyruvate N-acetyl-D- 8-oxo-GMP unsaturated sugar [DNA] 2 a 5,10- methyltransferase: GGPP kinase: thiL deacetylase: nagA catalase: kinase: thiL phosphate hydratase: 7-phosphate 3-phosphate glucosamine arsenite- H O hydroxyl radical 8-oxo-dGMP [acp] CoxB cytochrome methylenetetrahydrofolate menaquinol-6 biosynthesis BUE88_RS15440 2 an oxidized BUE88_RS05490 N-acetylglucosamine- erythritol ser chorismate BUE88_RS15135 6-phosphate erythritol/L-threitol translocating O c-type thiamine diphosphate 2 glutathione thiamine diphosphate serine--tRNA ligase: synthase: transaldolase: N-acetylglucosamine- 6-phosphate ATPase: an [amino group carrier protein]- a [2-oxoglutarate (9Z,15Z)-12,13- a reduced menaquinol-7 phosphopyruvate dehydrogenase: an oxidized 1-stearoyl- 1-cis- 4-hydroxybenzoyl- a guanine 966 a uracil 1498 cytochrome demethylmenaquinol-6 BUE88_RS07180 BUE88_RS16095 deacetylase: nagA O N 5 -methyltetrahydromethanopterin a cis- γ acetyl-CoA a 2-oxo 1-palmitoylglycerol a cis-delta13-3- a DNA segment L(or D)-O- an L-seryl- BUE88_RS02895 6-phosphate D-glucosamine BUE88_RS15035 2 an oleoyl-[acp] sn-glycerol vaccenoylglycerol- C-terminal- -(L-glutamate 5- dehydrogenase E2 protein] epoxy-octadeca- H O c-type hydratase: BUE88_RS06250 factor 420 CoA L-ornithine in 16S rRNA in 16S rRNA ala 2 demethylmenaquinone [tRNA ser ] transaldolase: tal vaccenoyl-[acp] carboxylate 6 3-phosphate oxo-C32:1-[acp] phosphoserine BUE88_RS15890 deacetylase: nagA 6-phosphate D-erythrulose 5,10-methylene 3-phosphate 3-phosphate semialdehyde-2-yl)-L-glutamate acetyl-CoA C- N -dihydrolipoyl-L-lysine 9,15-dienoate 16S rRNA 16S rRNA 3-oxoacyl-ACP recombinase: CtaD cytochrome methyltransferase: ser chorismate 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- N-acetyl-gamma- ornithine- 1-acyl-sn-glycerol- an oxidized a tRNA tetrahydromethanopterin acyltransferase: dihydrolipoyl BUE88_RS05380 phosphoserine alanine phosphoenol N-acetylglucosamine- 3-phosphate 3-phosphate glutamyl-phosphate -oxo-acid epoxide hydrolase: (guanine(966)-N(2) 3-phosphate (uracil(1498)-N(3))- reductase FabG: O c-type BUE88_RS05490 D-erythrose 2 D-erythrulose reductase: BUE88_RS06145 BUE88_RS08345 dehydrogenase: )-methyltransferase methyltransferase: recombinase phosphatase racemase: alr menaquinol-6 pyruvate F6P 6-phosphate acyltransferase: acyltransferase: reductase: transaminase: BUE88_RS03725 acyltransferase: BUE88_RS02435 cytochromea reduced 4-phosphate kinase: lpdA SerB: serB [+ 2 isozymes] deacetylase: nagA arsenite 5,10-methylene acetyl-CoA C- RsmD: 3 BUE88_RS00325 RecA: recA H O c-type α-D-glucosamine BUE88_RS04005 BUE88_RS04005 an [amino group carrierBUE88_RS08760 protein]- rocD a [2-oxoglutarate (9Z,15Z)-12,13- BUE88_RS04005 an N - 3-oxoacyl-ACP a DNA segment 2 pyruvate transketolase: BUE88_RS06260 BUE88_RS03980 D-glucosamine tetrahydromethanopterin γ acyltransferase: L-glutamate-5- a proteinogenic dehydrogenase E2 dihydroxyoctadeca- 2 1498 RS00190 cytochrome kinase: pyk 6-phosphate [+ 21-stearoyl-2- isozymes] [+ 2 isozymes]1,2-dicis- C-terminal- -(5-phospho- an N - 1-palmitoyl-2-[+ 2 isozymes] methyluracil reductase: in reverse serine D-ala an oxidized proline-- BUE88_RS02505 [+ 2 isozymes] reductase: BUE88_RS13460 BUE88_RS01125 semialdehyde amino acid 6 pro 6-phosphate acyl-carrier protein oleoyl-sn-glycerol acyl-carrier protein vaccenoyl- L-glutamyl)-L-glutamate protein] N -lipoyl-L-lysine 9,15-dienoate methylguanine 966 palmitoleoyl in 16S rRNA BUE88_RS14775 orientation O c-type Secondary glucosamine- D-erythrulose a reduced 5,10-methylene- 4-hydroxybenzoyl- a cis-delta13-3- 2 tRNA ligase: D-glyceraldehyde 3+ 3+ Metabolite pyruvate phosphoglucosamine 6-phosphate 3-phosphate phosphatidate in 16S rRNA phosphatidate hydroxyC32:1- Fe FecE Fe cytochrome BUE88_RS02990 NADH repair 4-phosphate factor 420 tetrahydromethanopterin acetyl-CoA L-histidine biosynthesis Amino Acid Biosynthesis an L-prolyl- 3-phosphate mutase: superpathway of branched chain amino acid biosynthesis L-arginine biosynthesis II (acetyl cycle) Biosynthesis deaminase: [acp] superpathway of L- L-lysine biosynthesis I superpathway of L- L-alanine [tRNA Pro ] BUE88_RS09935 nagB isoleucine biosynthesis I threonine biosynthesis biosynthesis III a tRNA Pro myo-inositol NADH D-glucosamine PRPP biosynthesis 1-stearoyl- 3D-(3,5/4)- 3-benzyl-3,6 - (12Z,15Z)-9,10- an [amino group carrier 6-O-cis-methoxy- a sugar RS12945 a sugar pyruvate N-acetylglutamyl-phosphate F6P 6 37 a CDP- sn-glycerol 6-trans-3-oxo- 5'-deoxy-5'- 1-palmitoylglycerol 5-deoxy-D- thr asp 1-phosphate D-erythrose N -dimethylallyladenosine a sulfurated an acyl-[acyl- γ (S)-dihydroorotate a cis-delta11-3- MEP oxaloacetate oxaloacetate cys D-glucopyranose sn-glycerol trihydroxycyclohexane- tridecenoyl-CoA bis(cysteinylglycine) fluoroadenosine epoxyoctadeca- protein]-C-terminal- - mycolyl-trehalose glucuronate ATP N-acetyl-gamma-glutamyl- 4-phosphate in tRNA [sulfur carrier] diacylglycerol 3-phosphate carrier protein] 3-phosphate oxo-C30:1-[acp] aspartate acetolactate aspartate kinase: aspartate UDP-N- 3-phosphate 1,2-dione acetyl-CoA C- - 6-(hydroxymethyl) purine-nucleoside 12,15-dienoate (L-glutamyl)-L-glutamate 1-deoxy-D-xylulose- 6-phosphate 5-deoxy- phosphoribosyltransferase: threonine cysteine desulfurase: 6-phosphate succinate CDP-diacylglycerol-- 1-acyl-sn-glycerol- 3D-(3,5/4)- 1-acyl-sn-glycerol- 3-oxoacyl-ACP synthase phosphate reductase: aminotransferase: acetylglucosamine acyltransferase: membrane phosphorylase: dihydroorotase: trehalose- aminotransferase: BUE88_RS05180 BUE88_RS05875 phenylalanine- dehydrogenase, glycerol-3-phosphate 3- 3-phosphate -diketopiperazine epoxide hydrolase: acetylglutamate 3-phosphate reductase FabG: 5-phosphate glucuronate BUE88_RS02755 ammonia-lyase: BUE88_RS08760 Carboxylate Degradation trihydroxycyclohexane- BUE88_RS02840 phosphatase: a sugar RS07630 a sugar BUE88_RS09570 small subunit: bifunctional glutamateacetylglutamate N- kinase: argB BUE88_RS09570 diphosphorylase/ BUE88_RS08345 dipeptidase: BUE88_RS04770 reductoisomerase: isomerase: BUE88_RS15950 L-aspartyl-4-phosphate cysteine desulfurase: -tRNA ligase hydrophobic phosphatidyltransferase: acyltransferase: 1,2-dione acylhydrolase 3-benzyl-3,6 - BUE88_RS03725 kinase: argB acyltransferase: BUE88_RS02435 1-(5-phospho- BUE88_RS04245 (R)-NADHX glucosamine-1- BUE88_RS06095 5-fluoro-5- otsB [+ 3 isozymes] acetyltransferase/amino- [+ 3 isozymes] BUE88_RS03730 subunit beta: Ins(3)P D-threitol membrane anchor pgsA BUE88_RS14730 acetyl-CoA C- (12Z,15Z)-9,10- an [amino group carrier BUE88_RS04005 BUE88_RS03015 trehalose- iolB β-D-ribosyl)-ATP (2Z)-2-aminobut- β 1-(3-sn- (decyclizing): iolD bis(cysteinyl)- 6- N-carbamoyl- 3-oxoacyl-ACP 1-deoxy-D- 5-dehydro- acid acetyltransferase NAD(P)H-hydrate phosphate N- degradation superpathway of -D- 5-deoxy-D- acyltransferase: gly deoxy-D-ribose adenine asp acetolactate asp ala BUE88_RS08765 pyruvate fermentation L-idonate degradation protein: sdhD 6 [+ 2 isozymes] (hydroxymethyl) dihydroxyoctadeca- protein]-C-terminal- [+ 2 isozymes] L-aspartate reductase: xylulose 5- cis-methoxy- 2-deoxy-D- phosphoribosyl- 2-enoate aspartate- acetyltransferase: glucuronosides degradation 2-methylsulfanyl-N - phosphatidyl) a 1-stearoyl 2- 1-phosphate 1-palmitoyl-2- + + synthase ArgJ: BUE88_RS08755 inositol epimerase: an unsulfurated CMP glucuronate BUE88_RS01125 12,15-dienoate γ mono-mycolate K KdpB K semialdehyde phenylalanine- to acetate IV met 5'-deoxyadenosine dimethylallyladenosine 37 -sn-glycerol acyl-carrier protein acyl-sn-glycerol -diketopiperazine -(5-phospho-L- cis-vaccenoyl a cis-delta11-3-BUE88_RS14775 phosphate gluconate ATP L-arginine biosynthesis I (via L-ornithine) monophosphatase: (S)-NADHX BUE88_RS09270 glmU D-threitol 4-trans- large subunit: N-acetylglutamate aspartate kinase: [sulfur carrier] acetyl-CoA glutamyl)-L-glutamate diphosphatase: aspartate kinase: dehydrogenase: -tRNA ligase D-threitol a β-D-glucuronoside L-idonate in tRNA 3-phosphate 3-phosphate undecenoyl-CoA phosphatidate hydroxyC30:1- BUE88_RS04250 synthase: BUE88_RS12310 phe BUE88_RS05455 N-acetyl-α-D- pyruvate BUE88_RS05180 BUE88_RS05175 BUE88_RS05180 subunit alpha: L-idonate 5- [acp] BUE88_RS02760 Glu N-acetyl-L-glutamate N-acetyl-L-glutamate 5-semialdehyde glucosamine dehydrogenase: BUE88_RS08770 β (S)-2-acetolactate 2-iminobutanoate Glu an L-phenylalanyl- myo-inositol BUE88_RS06245 dehydrogenase: predicted 1-(5-phospho- - L-aspartate- L-aspartyl- 1-phosphate L-aspartyl- acetylornithine [tRNA Phe ] D-glucopyranuronate BUE88_RS11275 ATP-driven D-ribosyl)-AMP semialdehyde D-erythrulose ditrans,octacis- 6-O-trans-keto- K + K + 4-phosphate 4-phosphate Phe UDP-N- 5-dehydro- ditrans,octacis- 6-cis, 3-oxo- a [protein]- all-trans- a double- ketol-acid aminotransferase: a tRNA NADH phytenate FAD a RNA-DNA hybrid 1-palmitoylglycerol pyridoxamine a cis-delta17-3- transporter phosphoribosyl- bifunctional acetylglucosamine D-gluconate a peptidoglycan with undecaprenyldiphospho- undecaprenyldiphospho- a purine tridecenoyl-CoA retinyl palmitate asp mycolyl-trehalose reductoisomerase: 4-hydroxy- BUE88_RS08745 D-erythrulose arsenate ATP H O L-threonine 3-phosphate 5'-phosphate oxo-C36:1-[acp] helix DNA of K+ glutamate N- aspartate- ribonucleoside 2 AMP aspartate- diphosphorylase/ (L-alanyl-γ-D-glutamyl- N-acetyl-(N-acetyl-β-D- N-acetyl-(N- long-chain fatty acetyl-CoA C- FAD:protein FMN ribonuclease HI: carboxylesterase/ 1-acyl-sn-glycerol- 3-oxoacyl-ACP 6-phosphate DNA BUE88_RS04240 tetrahydrodipicolinate kinase: acetyl-CoA formate 5-keto-D-gluconate purine-nucleoside ATPase: pyridoxine 5'- aspartate trehalose- semialdehyde acetyltransferase/ semialdehyde L-lysyl-D-alanyl-D- glucosaminyl)muramoyl- acid--CoA ligase: acyltransferase: transferase: BUE88_RS08575 lipase family helicase cyclohydrolase: (2R)-2,3- synthase: dapA glucosamine-1- BUE88_RS06260 5-reductase: acetylglucosaminyl) 3-phosphate reductase FabG: aminotransferase: 2-oxobutanoate amino-acid dehydrogenase: phosphorylase: BUE88_RS04420 phosphate oxidase: phosphatase: fluoride CrcB fluoride BUE88_RS02745 dehydrogenase: gln phosphate N- aldehydo-D-glucuronate phosphate alanine) pentapeptide L-alanyl-γ-D-glutamyl-L- muramoyl-L-alanyl-γ-D- BUE88_RS07510 BUE88_RS08345 BUE88_RS01515 ribonuclease HII: protein: acyltransferase: BUE88_RS02435 RecQ: dihydroxy-3- 4-hydroxy- [+ 2 isozymes] BUE88_RS11270 peptidoglycan BUE88_RS04770 BUE88_RS06880 BUE88_RS09570 otsB β BUE88_RS05175 acetyltransferase BUE88_RS05175 methionine-- lysyl-D-alanyl-D-alanine [+ 2 isozymes] [+ 6 isozymes] BUE88_RS08135 recQ 1-(5-phospho- -D-ribosyl)- methylbutanoate acetolactate met acetyltransferase: glucuronate acetyltransferase: a peptidoglycan with glycosyltransferase: isoglutaminyl-L-lysyl-peptidoglycan acetyl-CoA C- a [protein]-FMN- BUE88_RS03850 BUE88_RS04005 3-oxoacyl-ACP trehalose- an unwound ArgJ: tetrahydrodipicolinate D-erythrulose ribose-1-arsenate a purine base + AMP [+ 3 isozymes] 5-[(5-phosphoribosylamino) carbamoyl-phosphate L-aspartate- tRNA ligase: glmU BUE88_RS05215 D-gluconate di-trans,octa-cis (glycyl) -D-alanyl-D-alanine acyltransferase: H phosphate ADP a nucleoside 5'- [+ 4 isozymes] PLP trans-keto- L-aspartate- 2,3-dihydroxy- synthase synthase: dapA 4-phosphate isomerase: (L-alanyl-γ-D-glutamyl- BUE88_RS18770 5 di-trans,octa-cisglycosyltransferase: L-threonine DNA 1-palmitoyl-[+ 2 isozymes] reductase: oxaloacetate double- BUE88_RS08755 an L-methionyl- diphosphate AMP 2+ 2+ methylideneamino]imidazole- (2S,4S)-4- synthase large subunit: carB semialdehyde BUE88_RS07330 -undecaprenyl a peptidoglycan phytenoyl-CoA BUE88_RS01125 monophosphate palmitate a retinol mono-mycolate Cd CadA Cd semialdehyde isovalerate small subunit: N-acetyl-L-ornithine [elongator UDP-N- BUE88_RS15800 L-lysyl-D-alanyl-D- -undecaprenylBUE88_RS18770 2-myristoyl a cis-delta17-3-BUE88_RS14775 stranded DNA N-acetylglutamate acetyl phosphate diphosphate dimer (S. aureus) 4-cis- 4-carboxamide BUE88_RS04245 hydroxy-2,3,4,5- carbamoyl-phosphate bifunctional glutamate N- Met acetyl-CoA homoserine dehydratase: homoserine elongator tRNA ] acetylglucosamine alanine) pentapeptide diphosphate undecenoyl-CoA phosphatidate hydroxyC36:1- synthase: tetrahydrodipicolinate Met D-fructuronate bifunctional 1-(5- dehydrogenase: ilvD acetolactate synthase small subunit:acetyltransferase/amino- dehydrogenase: tRNA pyrophosphorylase: [acp] BUE88_RS12310 D-erythrose acetate kinase: pyruvate decarboxylation to acetyl CoA D-gluconate phosphoribosyl)-5-((5- synthase 4-hydroxy- BUE88_RS02830 acid acetyltransferase BUE88_RS03175 BUE88_RS16520 2+ 2+ BUE88_RS03175 3-methyl-2- D-mannonate 6-phosphate Cd RS15095 Cd phosphoribosylamino) tetrahydrodipicolinate ArgJ: BUE88_RS08755 4-phosphate BUE88_RS05210 oxobutanoate large subunit: N-acetyl-L- UDP-N-acetyl- oxidoreductase: L-ornithine a [pyruvate dehydrogenase 38- methylideneamino)imidazole- reductase: carbamoyl phosphate L-homoserine a very-long- an [amino group carrier protein]-C- 3-oxo-(11Z)- 5'-chloro-5'- a 1-phosphatidyl- a uridine 34 L-homoserine BUE88_RS04250 glutamate N-acetylglutamate α-D-glucosamine BUE88_RS15840 6 1-myristoylglycerol a cis-delta19-3- a nucleoside a cytidine acetate E2 protein] N -lipoyl-L-lysinepyruvate 16-hydroxypalmitate palmitate a purine 2'- enterobactin roseoflavin lys 4- carboxamide isomerase/ BUE88_RS17615 synthase: BUE88_RS12310 lysine- chain fatty acid terminal-γ-(L-ornithyl)-L-glutamate octadecenoyl-CoA deoxyadenosine 1D-myo-inositol 40 in tRNA 3-phosphate oxo-C38:1-[acp] diphosphate in tRNA Ile2 2-isopropylmalate branched-chain (S)-2-aceto-2- a tRNA Lys UDP-N-acetylglucosamine dehydrogenase long-chain fatty long-chain fatty long-chain fatty acetyl-CoA C- deoxyribonucleoside purine-nucleoside bifunctional phosphoribosylanthranilate acetylglutamate D-mannonate acetylornithine phosphatidylinositol tRNA 1-acyl-sn-glycerol- enterochelin 3-oxoacyl-ACP nucleoside- allantoin RS03005 allantoin homoserine kinase: synthase: leuA amino acid (S)-2,3,4,5- homoserine kinase: -tRNA 1-carboxyvinyltransferase: purine-nucleoside tRNA(Ile) hydroxybutanoate (acetyl-transferring) superpathway of acetate acid--CoA ligase: acid--CoA ligase: acid--CoA ligase: acyltransferase: phosphorylase: pseudouridine(38- riboflavin kinase/ isomerase PriA: kinase: argB tetrahydrodipicolinate BUE88_RS03165 ligase: lysS an L-lysyl- dihydrolipoyl aminotransferase: kinase: 3-phosphate esterase: reductase FabG: diphosphate -lysidine BUE88_RS03165 aminotransferase: ketol-acid BUE88_RS01575 bifunctional E1 component pyruvate BUE88_RS18710 BUE88_RS07510 BUE88_RS18710 BUE88_RS01125 phosphorylase: BUE88_RS04770 FAD synthetase: Lys mannitol utilization and formation 40) synthase TruA: BUE88_RS02435 kinase: BUE88_RS17735 (2S)-2- [tRNA ] dehydrogenase: BUE88_RS08745 BUE88_RS04770 BUE88_RS07050 acyltransferase: BUE88_RS02655 synthetase: BUE88_RS04210 reductoisomerase: N-acetylglutamyl- 2,3,4,5- UDP-N-acetylglucosamine degradation I D-altronate/D- subunit alpha: an [amino group carrier protein]- 2-deoxy-α- 5-chloro-5- a 1-phosphatidyl- BUE88_RS09960 N-(2,3- BUE88_RS02940 O-phospho- O-phospho- lpdA [+ 2 isozymes] [+ 2 isozymes] [+ 2 isozymes] acetyl-CoA C- BUE88_RS04005 3-oxoacyl-ACP BUE88_RS17300 tilS phosphoribulosylformimino- isopropylmalate phosphate tetrahydropyridine- lys 34 allantoin RS12795 allantoin BUE88_RS04240 ornithine L-homoserine 1-carboxyvinyltransferase: mannonate BUE88_RS13315 acetate C-terminal-γ-(L-glutamate 5- acyltransferase: D-ribose 1- a purine base adenine deoxyribose 1D-myo-inositol [+ 2 isozymes] dihydroxybenzoyl) roseoflavin a nucleoside a lysidine L-homoserine D-mannitol 16-hydroxypalmitoyl- a very-long-chain 38- reductase: AICAR-phosphate 2,6-dicarboxylate N- acetate--CoA [+ 2 isozymes] Ile2 3-isopropylmalate (R)-2,3-dihydroxy- N-acetyl-gamma- carbamoyltransferase: argF murA dehydratase: AMP diphosphate AMP diphosphate AMP diphosphate palmitoyl-CoA semialdehyde-2-yl)-L-glutamate BUE88_RS08345 phosphate 1-phosphate 4-phosphate a pseudouridine dimyristoyl -L-serine 5'-phosphate triphosphate in tRNA val threonine 1-phosphate ligase: acs CoA fatty acyl-CoA BUE88_RS14775 threonine dehydratase succinyltransferase: mannitol-1- BUE88_RS15845 40 in tRNA a cis-delta19-3- 3-methylpentanoate glutamyl-phosphate UDP-N-acetyl-α- acetate kinase: palmitoleoyl-CoA acetyl-CoA phosphatidate synthase: dapD synthase: hydroxyC38:1- imidazole glycerol small subunit: leuD reductase: D-glucosamine- phosphate 5- 2-dehydro-3- BUE88_RS05210 glycine glycine 2,3-dihydroxy-3- BUE88_RS03170 a [pyruvate dehydrogenase a [pyruvate dehydrogenase RS01715 BUE88_RS03170 N-succinyl-2-amino- histidine-- dehydrogenase: [acp] betaine betaine phosphate 3-isopropylmalate methylvalerate hydrogencarbonate BUE88_RS08760 his enolpyruvate deoxy-D-gluconate E2 protein] N 6 - E2 protein] N 6 -S- synthase dehydratase N-acetyl-L- 6-ketopimelate L-tryptophan biosynthesis tRNA ligase: BUE88_RS04955 thr hydro-lyase: ilvD thr UDP-N- dihydrolipoyl-L-lysine acetyldihydrolipoyl-L-lysine acetyl phosphate acetyl-CoA subunit HisF: large subunit: leuC carbamoyl- glutamate 5- BUE88_RS15885 an L-histidyl- acetylenolpyruvoylglucosamine a 2'- (1S,2R)-1- (S)-3-methyl-2- succinyldiaminopimelate mannitol-1- 3-oxo-(7Z)- a cis-delta21-3- BUE88_RS02750 phosphate semialdehyde L-citrulline [tRNA His ] 18-hydroxystearate 7-hydroxylaurate decanoate methyl (indol-3-yl)acetate deoxyribonucleoside [DNA] ethylphosphate vernolate L-arabinitol 3-methylcatechol a dipeptide phosphoenol phosphoenol threonine transaminase: dapC chorismate reductase: BUE88_RS05420 phosphate 5- tetradecenoyl-CoA C-(indol-3- predicted 2-isopropylmaleate oxopentanoate His ser oxo-C40:1-[acp] dGDP dADP synthase acetylornithine L-proline a tRNA long-chain fatty long-chain fatty long-chain fatty carboxylesterase/ acetyl-CoA C- 5'-triphosphate NAD(P)- yl)glycerol pyruvate pyruvate imidazole glycerol ammonia-lyase: UDP-N-acetyl- dehydrogenase: KDGP phosphate DNA polymerase alkaline phosphatase: catechol 2,3- 3-oxoacyl-ACP membrane ABC branched-chain large aminotransferase: N-succinyl-L,L-2,6- argininosuccinate biosynthesis I acid--CoA ligase: acid--CoA ligase: acid--CoA ligase: lipase family protein: acyltransferase: epoxide hydrolase: dependent alcohol glycine glycine phosphate BUE88_RS15950 3-isopropylmalate anthranilate synthase: α-D-muramate BUE88_RS04235 lipoate acetyltransferase: III subunit delta': BUE88_RS01865 3-phosphate tryptophan dioxygenase: reductase FabG: dipeptidase: pyruvate pyruvate transporter amino acid subunit: carB BUE88_RS08745 diaminopimelate synthase: BUE88_RS08735 BUE88_RS03725 dehydrogenase: betaine betaine synthase dehydratase BUE88_RS02740 F6P acetyl-CoA acetyltransferase: BUE88_RS18710 BUE88_RS18710 BUE88_RS18710 BUE88_RS08135 BUE88_RS01125 BUE88_RS05070 synthase BUE88_RS08365 BUE88_RS02435 BUE88_RS06095 kinase: pyk kinase: pyk of glycine (2Z)-2-aminobut- aminotransferase: BUE88_RS05215 alkaline phosphatase: succinyl- argininosuccinate lpdA [+ 2 isozymes] [+ 2 isozymes] [+ 2 isozymes] [+ 4 isozymes] (9Z)-12,13- BUE88_RS01710 subunit subunit HisH: small subunit: leuD carbamoyl- N-acetyl-L- Glu acetyl-CoA C- [+ 10 isozymes] BUE88_RS15185 cis,cis-2-hydroxy- 3-oxoacyl-ACP betaine 2-enoate BUE88_RS04210 diaminopimelate synthase: BUE88_RS09060 a proteinogenic dGTP pyruvate dATP pyruvate BUE88_RS17730 phosphate ornithine anthranilate glycine-- D-glyceraldehyde MeOH (indol-3-yl)acetate acyltransferase: dihydroxyoctadeca- [+ 3 isozymes] beta: trpB 6-oxohepta- 3-isopropylmalate glutamate 5- gly pyruvate 18-hydroxystearoyl- 7-hydroxylauroyl- [DNA] ethanol D-glyceraldehyde reductase: amino acid desuccinylase: UDP-N-acetyl- AMP diphosphate AMP diphosphate diphosphate AMP decanoyl-CoA 9-enoate trp dehydratase synthase L-arginino-succinate kinase: proB tRNA ligase: 3-phosphate CoA CoA BUE88_RS08345 L-arabinopyranose 3-phosphate 2,4-dienoate BUE88_RS14775 a cation RS10325 a cation ile BUE88_RS16325 anthranilate γ α-D-muramoyl- (5Z)- a cis-delta21-3- D-erythro- large subunit: leuC small subunit: -L-glutamyl BUE88_RS00390 acetyl-CoA AICAR phosphoribosyltransferase: trpD a glycyl-[tRNA Gly ] L-alanyl-γ-D- dodecenoyl-CoA hydroxyC40:1- imidazole-glycerol- BUE88_RS02830 argininosuccinate 5-phosphate 2-iminobutanoate (2R,3S)-3- L,L-diaminopimelate glutamyl-meso-2,6- [acp] phosphate lyase: argH a tRNA Gly isopropylmalate carbamoyl N-(5-phosphoribosyl)-anthranilate glutamate-5- imidazoleglycerol- L-ornithine diaminopimelate a cation RS05640 a cation phosphate diaminopimelate semialdehyde Amine and Polyamine Degradation 3-isopropylmalate (R)-4'- 747 3-oxo-4- phosphate phosphoribosylanthranilate dehydrogenase: α,ω-9Z- a [protein] N-terminal- (+)-7-epi- a uracil (7Z)- a negatively dehydrogenase: L-proline biosynthesis III epimerase: arg α-linolenate all-trans-retinyl palmitate NADH H O a quinone histidinol dehydratase HisB: phosphopantothenoyl- octadecenedioate formyl-L-methionine 3'-dephospho- jasmonoyl-CoA 2 roseoflavin tetradecenoyl-CoA pregnene-20- supercoiled DNA BUE88_RS17695 isomerase: BUE88_RS14105 BUE88_RS17355 ATP ATP in 23S rRNA BUE88_RS04215 ornithine 4-aminobutanoate L-cysteine long-chain fatty long-chain fatty carboxylesterase/ peptide CoA NADH acyl-CoA 5'-phosphate 23S rRNA acyl-CoA carboxyl-CoA NADPH:quinone DNA BUE88_RS17725 2-oxobutanoate allantoin degradation bifunctional histidinol a cation RS17280 a cation carbamoyltransferase: bifunctional 1-(5- L-glutamate-5- methionine-- creatinine 4-aminobutanoate urea degradation I dephospho- acetyl-CoA C- (2S)-2-isopropyl- met degradation I acid--CoA ligase: acid--CoA ligase: lipase family protein: deformylase: pyrophosphatase: thioesterase: bifunctional (uracil(747)-C(5))- dehydrogenase: reductase: topoisomerase dehydrogenase: imidazole acetol- Glu meso-diaminopimelate tRNA ligase: to ureidoglycolate II phosphopantothenoylcysteine CoA kinase: acyltransferase: 3-oxosuccinate argF L-methionine biosynthesis III phosphoribosyl)-5-((5- semialdehyde degradation I degradation III BUE88_RS07510 BUE88_RS07510 BUE88_RS17870 BUE88_RS18705 BUE88_RS16440 BUE88_RS14115 riboflavin kinase/ methyltransferase BUE88_RS15605 BUE88_RS17890 I: topA phosphate acetolactate (ammonia producing) decarboxylase/ hisD phosphoribosylamino) BUE88_RS07330 an L-methionyl- 4-aminobutanoate BUE88_RS02610 reduced β- BUE88_RS08345 synthase urea [+ 2 isozymes] [+ 2 isozymes] [+ 4 isozymes] peptide [+ 3 isozymes] FAD synthetase: RlmC: [+ 6 isozymes] [+ 2 isozymes] [+ 2 isozymes] diaminopimelate Met creatinine 4-aminobutanoate phosphopantothenate-- + histidinol- glutamate 5- methylideneamino)imidazole- [initiator tRNA ] 4-aminobutyrate- (S)-(+)-allantoin ω-carboxy- ADP coenzyme A H nicotinamide D- AMP (+)-7-epi- BUE88_RS02940 BUE88_RS12720 (2E,7Z)- acetyl-CoA C- his a cation RS15115 a cation small subunit: Met cysteine ligase CoaBC: coaBC palmitate all-trans-retinol deformylase: def roseoflavin adenine a semiquinone a relaxed DNA phosphate kinase: proB L-citrulline decarboxylase: lysA L-homoserine 4- carboxamide isomerase/ initiator tRNA -2-oxoglutarate creatininase: 4-aminobutyrate- putrescine degradation IV α an N-terminal L- ribonucleotide jasmonate a 5-methyluracil 747 tetradecenoyl-CoA acyltransferase: BUE88_RS04245 allantoinase AMP diphosphate -linolenoyl-CoA AMP diphosphate (9Z)-octadec- -2-oxoglutarate 4'-phosphopantetheine formate dinucleotide transaminase: 4-methyl-2- homoserine O- phosphoribosylanthranilate (S)-1-pyrroline- transaminase: BUE88_RS06875 AllB: allB 9-enoyl-CoA methionyl-[protein] in 23S rRNA BUE88_RS01125 γ-L-glutamyl urea-1-carboxylate 3,22-dioxochol- BUE88_RS13310 acetolactate oxopentanoate L-ornithine argininosuccinate lys acetyltransferase: isomerase PriA: 5-carboxylate gabT transaminase: 5-phosphate succinate creatine allantoate putrescine 4-en-24-oyl-CoA a cation RS01395 a cation synthase synthase: BUE88_RS03530 BUE88_RS17735 gabT histidinol- branched-chain pyrroline-5- semialdehyde succinate allophanate large subunit: BUE88_RS08735 hydrogen sulfide O-acetyl-L-homoserine phosphate amino acid 1-(o-carboxyphenylamino)-1'- carboxylate allantoate semialdehyde hydrolase subunit putrescine oxidase: BUE88_RS04250 ornithine- glutamate-5- NAD-dependent a [protein]- transaminase: aminotransferase: argininosuccinate deoxyribulose 5'-phosphate reductase: amidohydrolase: 1: BUE88_RS03440 BUE88_RS11590 (15Z)- dihomo γ- succinate- pristanate linoleate a carboxylic ester carbamoyl hexulose 6- a ribonucleoside H O xylitol oleoyl-CoA MeOH π (S)-2-aceto-2- -oxo-acid semialdehyde O-acetyl-L-homoserine succinate- 2 NMN [DNA] N -phospho- (S)-malate BUE88_RS17720 BUE88_RS04210 synthase: proC BUE88_RS06115 tetracosenoate asp linolenoyl-CoA a cation RS13270 a cation sulfhydrolase: indole-3-glycerol semialdehyde allophanate phosphate phosphate 5'-monophosphate hydroxybutanoate transaminase: dehydrogenase: BUE88_RS09060 superpathway of L-serine semialdehyde 4-aminobutanal long-chain fatty long-chain fatty long-chain fatty carboxylesterase/ acyl-CoA bifunctional NAD(P)- acyl-CoA bifunctional 3'- catalase: L-histidine class II phosphate synthase dehydrogenase: hydrolase: aspartate 3-hexulose- bifunctional L-histidinol- rocD BUE88_RS17355 and glycine biosynthesis I BUE88_RS07265 dehydrogenase: sarcosine (S)-ureidoglycine acid--CoA ligase: acid--CoA ligase: acid--CoA ligase: lipase family protein: thioesterase: dependent alcohol dehydrogenase: BUE88_RS14475 histidine ketol-acid leu L-arginino- pro carbamoyltransferase 6-phosphate metallophosphatase/ metallophosphatase/ 5' exonuclease/ fumarate phosphate TrpC: BUE88_RS02725 BUE88_RS05025 BUE88_RS11585 BUE88_RS03445 dehydrogenase: phosphatase: reductoisomerase: O-acetylhomoserine BUE88_RS18710 BUE88_RS18710 BUE88_RS18710 BUE88_RS08135 synthase: 5'-nucleotidase: BUE88_RS14115 5'-nucleotidase: BUE88_RS15605 DNA polymerase: catalase: hydratase: succinate aminobutyraldehyde catalytic subunit: BUE88_RS07060 a cation RS10855 a cation histidinol BUE88_RS04240 3-phospho-D-glycerate aminocarboxypropyltransferase/ (1S,2R)-1-C-(indol-3- [+ 2 isozymes] [+ 2 isozymes] [+ 2 isozymes] [+ 4 isozymes] [+ 3 isozymes] BUE88_RS06935 BUE88_RS01710 [+ 6 isozymes] BUE88_RS10665 BUE88_RS15440 aspA L-glutamate-5- NAD-dependent succinate ammonium BUE88_RS02845 BUE88_RS00635 BUE88_RS06935 1-(β-D argininosuccinate phosphoglycerate dehydrogenase: D-ribulose di-homo-γ- (2E,9Z)- a [protein]- phosphatase: (R)-2,3-dihydroxy- semialdehyde cysteine synthase: yl)glycerol 3-phosphate succinate- a carboxylate an alcohol N-carbamoyl- [+ 3 isozymes] [+ 4 isozymes] formaldehyde fumarate Cell Structure Biosynthesis BUE88_RS11670 (Z)-15- formaldehyde a ribonucleoside ribofuranosyl) L-histidine BUE88_RS03640 lyase: argH dehydrogenase: BUE88_RS03670 AMP diphosphate AMP diphosphate pristanoyl-CoA AMP diphosphate linoleoyl-CoA L-aspartate 5-phosphate linolenate octadecenoyl-CoA a nucleoside 5'- 3-methylpentanoate tryptophan synthase semialdehyde (S)-ureidoglycolate 1-pyrroline tetracosenoyl-CoA nicotinamide D-xylopyranose BUE88_RS04220 gly monophosphate 2,3-dihydroxy-3- subunit alpha: dehydrogenase: a cation RS09785 a cation histidinol arg 3-phosphooxypyruvate L-homocysteine peptidoglycan biosynthesis I (meso-diaminopimelate containing) methylvalerate BUE88_RS17475 BUE88_RS11585 4-aminobutanoate putrescine degradation I histidinol hydro-lyase: ilvD (S)-1-pyrroline- phosphoserine [+ 2 isozymes] 5-methyltetrahydropteroyltriglutamate- UDP-N-acetyl-α-D-glucosamine succinate 3E,5Z- a long-chain a [protein]-L- a [protein]- dehydrogenase: 5-carboxylate transaminase: 18-hydroxyoleate octanoate an alkylated DNA a nucleoside scyllo-inosose H O a [protein] Ser/Thr lauroyl-CoA H O ethanol ethanol τ (S)-3-methyl-2- - homocysteine S- ser stearoyl-CoA a ferrocytochrome b 2 2 ω N -phospho- L-dopa citrate RS07980 citrate indole 5 tetradecadienoyl-CoA fatty acyl-CoA proline ( = 180) hisD pyrroline-5- BUE88_RS09170 UDP-N-acetylglucosamine putrescine triphosphate oxopentanoate methyltransferase: BUE88_RS12425 long-chain fatty acyl-CoA desaturase: long-chain fatty acyl-CoA DNA-3- acyl-CoA serine/threonine acyl-CoA peptidylprolyl NAD(P)- catalase: L-histidine 1-carboxyvinyltransferase: NTP 2-keto-myo-inositol carboxylate acid--CoA ligase: acid--CoA ligase: thioesterase: methyladenine thioesterase: protein kinase: thioesterase: isomerase: dependent alcohol BUE88_RS14475 histidine aromatic acid histidinal branched-chain 5-methyltetrahydropteroyltriglutamate- BUE88_RS17880 dehydratase: reductase: 3-phospho-L-serine BUE88_RS01575 pyrophosphohydrolase: phosphatase: decarboxylase: amino acid tryptophan synthase BUE88_RS18710 BUE88_RS18710 BUE88_RS14115 glycosylase: BUE88_RS18490 BUE88_RS10655 BUE88_RS18490 BUE88_RS11500 dehydrogenase: catalase: - homocysteine methyltransferase: acyl-CoA desaturase: BUE88_RS11945 BUE88_RS16080 biotin RS02460 biotin histidinol proC subunit beta: trpB UDP-N-acetylglucosamine 4-aminobutanal BUE88_RS10455 3D-(3,5/4)- BUE88_RS01710 BUE88_RS07060 BUE88_RS15320 aminotransferase: BUE88_RS15345 [+ 2 isozymes] BUE88_RS01775 [+ 2 isozymes] [+ 3 isozymes] a DNA containing [+ 3 isozymes] [+ 5 isozymes] [+ 3 isozymes] [+ 2 isozymes] BUE88_RS15440 S-adenosyl-L-methionine cycle II 1-carboxyvinyltransferase: (3E,5Z)- a nucleoside 5'- a long-chain a [protein]-L- a [protein]- dehydrogenase: BUE88_RS04210 phosphoserine coenzyme A an alkylated trihydroxycyclohexane- a [protein] (L-serine/L- laurate [+ 3 isozymes] acetaldehyde dopamine aminobutyraldehyde Alcohol Degradation 18-hydroxyoleoyl- a ferricytochrome b oleoyl-CoA an apurinic/ ω L-histidine pro phosphatase SerB: serB murA AMP diphosphate 5 diphosphate AMP octanoyl-CoA tetradecadienoate monophosphate fatty acid proline ( = 0) hisD met nucleobase 1,2-dione threonine) phosphate acetaldehyde trp dehydrogenase: CoA apyrimidinic site ile UDP-N-acetyl-α-D- sulfite RS11110 sulfite met BUE88_RS11670 his ser glucosamine-enolpyruvate glycerol and glycerophosphodiester degradation UDP-N- 4-aminobutanoate serine a DNA containing decaprenyl- an N 3 -methyladenine 6-methoxy-2-all- 1-oleyl-2-lyso- 5-methyltetrahydropteroyltriglutamate- acetylenolpyruvoylglucosamine glycerol a glycerophosphodiester a [protein]- (-)-methyl jasmonate (R)-mevalonate NaMN oleoyl-CoA H O D-threo-isocitrate cerotoyl-CoA 5-hydroxy- palmitoyl-CoA a ferrocytochrome b S methyl pyrophosphoryl-(N trans-octaprenyl- 2 phosphatidate ser sulfite RS12880 sulfite - homocysteine S- hydroxymethyltransferase: reductase: BUE88_RS05420 C1 Compound Utilization and Assimilation 5 p L-cysteine in DNA diphosphate GTP H O L-tryptophan BUE88_RS09515 acyl-CoA desaturase: phosphotriester methylated-DNA-- -acetylglucosamine) DNA-3- 1,4-benzoquinone carboxylesterase/ bifunctional 2 acyl-CoA isocitrate 1-acyl-sn-glycerol- acetyl-/propionyl- methyltransferase: BUE88_RS12425 methionine Glu demethylmenaquinone GTPase aromatic acid L-serine glycerol glycerophosphodiester BUE88_RS17880 [protein]-cysteine S- -N-acetylmuramyl- methyladenine lipase family protein: diphosphomevalonate metallophosphatase/ thioesterase: dehydrogenase 3-phosphate CoA carboxylase peptidoglycan L-cysteine 5-methyltetrahydropteroyltriglutamate- adenosyltransferase: ala UDP-N-acetyl-α-D-muramate formaldehyde oxidation glycosylase I: methyltransferase: BUE88_RS08135 5'-nucleotidase: ObgE: obgE BUE88_RS18490 (NADP(+)): acyltransferase: subunit alpha: decarboxylase: ammonia-lyase: gly formate assimilation into 5,10- formaldehyde oxidation kinase: phosphodiesterase: acyl-CoA desaturase: methyltransferase: (pentapeptide) decarboxylase: mvaD - homocysteine methyltransferase: BUE88_RS02805 glutamate racemase: VII (THF pathway) glycosyltransferase: BUE88_RS05490 [+ 3 isozymes] BUE88_RS15320 BUE88_RS10735 sulfite RS12850 sulfite biosynthesis I glpK BUE88_RS09755 BUE88_RS10450 ω, mono- BUE88_RS05825 [+ 4 isozymes] BUE88_RS06935 [+ 3 isozymes] BUE88_RS10845 BUE88_RS04005 BUE88_RS04750 methylenetetrahydrofolate II (glutathione-dependent) BUE88_RS01775 a DNA without a peptidoglycanBUE88_RS18770 3-methyl-6-methoxy- BUE88_RS15345 BUE88_RS16545 a [protein]-S- an apurinic site β-D- phosphate GDP H + 2-carboxy- UDP-N-acetylmuramate- S methyl trans,octa-cis 3-methyladenine 2-octaprenyl-1,4- MeOH (-)-jasmonate IPP oleate 2-oxoglutarate [+ 2 isozymes] serotonin pyruvate formaldehyde a ferricytochrome b palmitoleoyl-CoA p dimer within DNA ribosylnicotinate dioleoyl cerotoyl-CoA ser -L-alanine ligase: murC formate formaldehyde 5 methyl-L-cysteine -decaprenyl benzoquinone L-homocysteine SAM sn-glycerol phosphotriester (mycobacteria) D-glt phosphatidate 2+ 2+ serine 3-phosphate diphosphate Mg RS16380 Mg UDP-N-acetyl-α-D-muramoyl-L-alanine acetyltransferase: a 5,10- 10 glycerol-3- BUE88_RS06080 an N - S-(hydroxymethyl) a [2-oxoglutarate- a [protein]- 6-O-α-mycolyl- UDP-N-acetylmuramoyl- methylenetetrahydrofolate phosphate 2-hydroxy-4-oxobutane- + 3-[(6'-methylthio) O-acetyl-L-serine formyltetrahydrofolate glutathione 2-methylbutanoate [DNA] FMNH NADP methylsalicylate preuroporphyrinogen (R)-mevalonate palmitoleoyl-CoA dehydrogenase a sulfurated a purine 2 phe thr N-phospho- trehalose 6- L-alanine--D-glutamate bifunctional dehydrogenase: SAM 1,2,4-tricarboxylate 5-phosphate hexyl]malate chloride RS06170 chloride bifunctional glutathione- E2 protein] N 6 - [sulfur carrier] acetate- exodeoxyribonuclease 4-carboxy-4-hydroxy- ribonucleoside NADPH-dependent carboxylesterase/ acyl-CoA L-histidine phosphate ligase: BUE88_RS18790 methylenetetrahydrofolate BUE88_RS09805 uroporphyrinogen- 3-isopropylmalate aspartate cysteine adenosylhomocysteinase: dependent lipoyl purine-nucleoside phosphomevalonate threonine histidine trehalose- methylenetetrahydrofolate octanoyl-L-lysine -CoA III: BUE88_RS04985 2-oxoadipate FMN reductase: lipase family protein: III synthase: dehydrogenase: dehydrogenase: synthase A: cysK dehydrogenase/ synthase: phosphorylase: kinase: aminotransferase: phosphatase: phosphatase: BUE88_RS04500 meso-diaminopimelate α dehydrogenase/ formaldehyde DHAP ligase: acs aldolase/oxaloacetate BUE88_RS17570 BUE88_RS08135 BUE88_RS15605 ammonia-lyase: UDP-N-acetyl- -D-muramoyl- methenyltetrahydrofolate a [2-oxoglutarate exodeoxyribonuclease BUE88_RS11995 BUE88_RS04215 BUE88_RS09570 [+ 2 isozymes] dehydrogenase: lipA BUE88_RS04770 BUE88_RS07600 BUE88_RS15950 BUE88_RS07060 otsB adenosylhomocysteinase: D-ala L-alanyl-D-glutamate methenyltetrahydrofolate III: xth decarboxylase: ligK α-D-ribose- [+ 2 isozymes] [+ 4 isozymes] [+ 6 isozymes] cyclohydrolase: an unsulfurated dehydrogenase 2-methylbutanoyl- a 2'- (R)-mevalonate 9-(methylthio)- [+ 3 isozymes] a [protein]- α, α'-trehalose BUE88_RS08940 cyclohydrolase: BUE88_RS12900 5'-deoxyadenosine met AMP diphosphate a purine base + uroporphyrinogen-III (2E,9Z)- cys BUE88_RS09510 [sulfur carrier] E2 protein] N 6 CoA oxaloacetate pyruvate 1-phosphate H NADPH FMN MeOH salicylate 2-oxononanoate keto- 2-oxobutanoate deoxyribonucleoside [DNA] diphosphate hexadecenoyl-CoA L-histidine 6-α-mycolate SAH D-alanine--D-alanine UDP-N-acetylmuramoyl- BUE88_RS09510 phenylpyruvate Carbohydrate Biosynthesis a 5,10- S-formylglutathione -lipoyl-L-lysine 5'-monophosphate ligase: BUE88_RS11385 L-alanyl-D-glutamate-- a 5,10- 2, 6-diaminopimelate methenyltetrahydrofolate D-alanine--D-alanine methenyltetrahydrofolate UDP-N-acetyl-D- 6 ligase: BUE88_RS18775 bifunctional a [pyruvate an O - D-xylulose 6-phospho an (S)-2- β-D-fructofuranose (7Z)- 6-O-cis-keto- ligase: BUE88_RS03995 dTDP-L-rhamnose bifunctional a [protein]- an insertion sequence 3-[(3'-methylthio) glucosamine biosynthesis I dehydrogenase a sulfurated methylguanine D-glucono- uroporphyrinogen-I β-alanine thr mycolyl-trehalose (R)-mevalonate biosynthesis I methylenetetrahydrofolate 5-phosphate oxaloacetate ITP halocarboxylate 1-phosphate element IS30 hexadecenoyl-CoA propyl]malate α methylenetetrahydrofolate SAM 6 L-cysteine Fatty Acid and Lipid Biosynthesis D-alanyl-D-alanine UDP-N-acetyl- -D-muramoyl-L-alanyl- D-glucopyranose dehydrogenase/ E2 protein] N - [sulfur carrier] in DNA phosphoketolase: 1,5-lactone haloacid fructose- acyl-CoA 6-phosphate α dehydrogenase/ formate methylated-DNA-- phosphoenolpyruvate uroporphyrinogen 3-isopropylmalate 4-aminobutyrate- γ-D-glutamyl-meso-2,6-diaminopimelate -D-glucopyranose octanoyl-L-lysinelipoyl BUE88_RS13155 dehalogenase: bisphosphate transposase: dehydrogenase: L-threonine 3- trehalose- mevalonate 6-phosphate methenyltetrahydrofolate [protein]-cysteine S- 6-phosphogluconolactonase: decarboxylase: dehydrogenase: -2-oxoglutarate glucose-6- 1-phosphate methenyltetrahydrofolate synthase: carboxykinase (GTP) BUE88_RS07175 BUE88_RS15005 BUE88_RS15605 dehydrogenase: phosphatase: kinase: mvk stearate biosynthesis cyclohydrolase: phosphoketolase: pgl aldolase: BUE88_RS11955 BUE88_RS04215 fatty acid elongation -- saturated UDP-N-acetylmuramoyl- phosphate glucose-1-phosphate cyclohydrolase: lipA a [pyruvate methyltransferase: : BUE88_RS08250 transaminase: BUE88_RS02795 otsB gondoate biosynthesis biotin-carboxyl carrier fatty acid BUE88_RS09510 Nucleoside and Nucleotide Degradation BUE88_RS01475 [+ 7 isozymes] BUE88_RS10730 an insertion [+ 6 isozymes] II (bacteria and plants) thymidylyltransferase: an unsulfurated dehydrogenase BUE88_RS10450 D-gluconate phosphoenol 6-(methylthio)- gabT (R)-mevalonate (anaerobic) protein assembly biosynthesis initiation I tripeptide--D-alanyl- isomerase: BUE88_RS09510 5'-deoxyadenosine met D-glyceraldehyde IDP an (R)-2- coproporphyrinogen I (2E,7Z)- trehalose-cis-keto- an N 10 - 6 a [protein]-S- pyruvate a halide anion D-glyceraldehyde DHAP sequence IS30 with 2-oxohexanoate aminoacetone D- alanine ligase: BUE88_RS07650 rfbA [sulfur carrier] E2 protein] N a guanine in DNA acetyl phosphate 6-phosphate hydroxyacid hexadecenoyl-CoA 3-oxopropanoate mono-mycolate 5-phosphate dTDP-α-D-glucose a 5,10- methyl-L-cysteine 3-phosphate integrated transposon an acetoacetyl-[acp] a [biotin carboxyl- formyltetrahydrofolate superpathway of purine deoxyribonucleosides degradation -lipoyl-L-lysine a palmitoyl-[acp] acetyl-CoA BUE88_RS18780 methylenetetrahydrofolate purine nucleotides degradation II (aerobic) a malonyl-[acp] an oleoyl-[acp] carrier protein]-L-lysine glucose-6- 3-oxo-stearoyl- acetyl-/propionyl- dTDP-glucose 4,6- formyltetrahydrofolate (11Z)-3-oxo- α phosphate [acp] synthase: biotin--[acetyl-CoA- UDP-N-acetyl- -D-muramoyl-L- dehydratase: rfbB deformylase: purU 4 a [protein]- CoA carboxylase isomerase: undecaprenyl-diphospho-N an O - a dimer of non-adjacent icosapentaenoyl- an (R)-2- 3-[(7'-methylthio) BUE88_RS00495 icos-11-enoyl- carboxylase] ligase: alanyl-γ-D-glutamyl-meso-2,6- 2'-deoxyguanosine a [protein]- nicotinate PRPP porphobilinogen 2-hydroxyisobutyramide palmitoyl-CoA H O a folate NAD + prephenate subunit alpha: di-trans,octa-cis-undecaprenyl phosphate dTDP-4-dehydro-6- -acetylmuramoyl-L-alanyl-γ- UDP-N-acetyl-α-D-glucosamine methylthymine 2 L-tyrosine his a 3-oxooctadecanoyl- [acp] synthase: BUE88_RS02515 AMP L-cysteine 2'-deoxycytidines in DNA CoA halocarboxylate heptyl]malate BUE88_RS04710 BUE88_RS04750 diaminopimeloyl-D-alanyl-D-alanine deoxy-α-D-glucopyranose formate 2'-deoxyadenosine D-glutamyl-L-lysyl- D-alanine in DNA nicotinate acyl-CoA HAD family acyl-CoA dihydrofolate NADH phosphate [acp] an (11Z)-3-BUE88_RS00495 a [biotin carboxyl- F6P undecaprenyldiphospho- methylated-DNA-- deoxyribodipyrimidine hydroxymethylbilane 3-isopropylmalate prephenate malonyl-CoA dTDP-4- phosphoribosyltransferase: thioesterase: hydrolase: amidase: thioesterase: reductase: pyrophosphatase: protein-tyrosine- histidine oxo-icos-11- a 3-oxoacyl-[acp] bifunctional muramoylpentapeptide beta-N- photo-lyase: synthase: dehydrogenase: dehydratase: 3-oxoacyl-ACP carrier protein]-N [protein]-cysteine S- phosphatase: ammonia- 3-oxoacyl-ACP glutamine-- dehydrorhamnose purine-nucleoside IMP BUE88_RS09720 BUE88_RS14115 BUE88_RS09080 BUE88_RS03345 BUE88_RS18490 BUE88_RS12130 BUE88_RS16440 reductase FabG: enoyl-[acp] 6 -biotinyl-L-lysine ACP S- metallophosphatase/ acetylglucosaminyltransferase: methyltransferase: BUE88_RS05670 BUE88_RS11990 BUE88_RS04215 BUE88_RS07190 reductase: fructose-6- 3,5-epimerase: BUE88_RS12080 lyase: hutH 3-oxoacyl-ACP adenosine phosphorylase: 5'-nucleotidase: murG BUE88_RS10450 [+ 2 isozymes] [+ 3 isozymes] [+ 4 isozymes] 2-hydroxy-2- [+ 3 isozymes] [+ 3 isozymes] 10-(methylthio)- keto- BUE88_RS02435 malonyltransferase: undecaprenyldiphospho- ditrans,octacis-undecaprenyldiphospho- a cytosine in DNA an (R)-2- preuroporphyrinogen NMN AMP a [protein]- reductase: BUE88_RS14775 phosphate BUE88_RS04620 deaminase: BUE88_RS04770 IMP a [protein]-S- NaMN coenzyme A icosapentaenoate a halide anion palmitate a 7,8-dihydrofolate urocanate BUE88_RS00510 N-acetylmuramoyl-L-alanyl- BUE88_RS06935 UDP N-acetyl-(N-acetylglucosaminyl)muramoyl- a thymine in DNA methylpropanoate 2-oxodecanoate phenylpyruvate L-tyrosine 3-oxoacyl-ACP transaminase dTDP-4-dehydro- purine-nucleoside methyl-L-cysteine hydroxyacid BUE88_RS14775 3-oxoacyl-ACP γ BUE88_RS04785 dehydrogenase: L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine reductase: a [biotin carboxyl- -D-glutamyl-meso-2,6- β-L-rhamnose phosphorylase: reductase FabG: (isomerizing) adenosine BUE88_RS09840 BUE88_RS14775 3-oxoacyl-ACP β-ketoacyl- a malonyl-[acp] diaminopimeloyl-D-alanyl-D-alanine carrier-protein dimer]- : glmS dTDP-4- BUE88_RS04770 purine-nucleoside GMP reductase FabG: ACP synthase: BUE88_RS02435 IMP a (3R)-3- N 6 -biotinyl-L-lysine undecaprenyldiphospho- phosphorylase: decaprenyl-diphospho-N- UDP-N-acetyl- all-trans- a (3R)-3- dehydrorhamnose an (R)-2- + 3-[(4'-methylthio) orotidine 5'- hydroxyoctadecanoyl- BUE88_RS02435 a 2,3,4-saturatedBUE88_RS00495 3-oxoacyl-ACP glutamine-- 2'-deoxyinosine adenosine dehydrogenase: 2-carboxy-1,4- glycerophosphoserine icosapentaenoate coenzyme A FMNH NAD oxaloacetate stearoyl-CoA H O DNA with lesion 3-methylcatechol 3-ethylmalate a D-hexose acetyl-/propionyl- muramoylpentapeptide beta-N- BUE88_RS04770 acetylmuramoyl-pentapeptide α-D-glucosamine dodecaprenyl 2 L-allo-threonine 2 a (3R,11Z)-3- hydroxyacyl-[acyl- reductase: rfbD bifunctional naphthoquinol halocarboxylate butyl]malate phosphate [acp] fatty acyl-[acp] synthase III: fructose-6- deaminase: BUE88_RS16660 undecaprenyldiphospho- HAD family glycerophosphodiester NADPH-dependent acyl-CoA excinuclease carrier protein] CoA carboxylase biotin carboxylase: acetylglucosaminyltransferase: diphosphate long-chain fatty low specificity L- phosphoenolpyruvate 3-isopropylmalate catechol 2,3- 3-isopropylmalate hydroxy-icos- BUE88_RS07750 Metabolic Regulator Biosynthesis phosphate dTDP-β-L-rhamnose 2-deoxy-α-D- BUE88_RS04785 metallophosphatase/ 1,4-dihydroxy- glucokinase: orotidine-5'- subunit alpha: BUE88_RS04750 murG muramoylpentapeptide beta-N- hydrolase: phosphodiesterase: acid--CoA ligase: FMN reductase: thioesterase: ABC subunit UvrA: 11-enoyl-[acp] transaminase ribose 1-phosphate 5'-nucleotidase: 2-naphthoate threonine aldolase: carboxykinase (GTP) dehydrogenase: dioxygenase: dehydrogenase: BUE88_RS18715 phosphate BUE88_RS04750 XMP acetylglucosaminyltransferase: BUE88_RS09080 BUE88_RS09755 BUE88_RS07510 BUE88_RS17570 BUE88_RS18490 BUE88_RS00665 an acetoacetyl-[acp] BUE88_RS06935 polyprenyltransferase: BUE88_RS04060 : BUE88_RS08250 BUE88_RS04215 BUE88_RS08365 BUE88_RS04215 decarboxylase: ppGpp biosynthesis lipid II (meso diaminopimelate containing) (isomerizing) inosine murG sn-glycerol a [carboxyl-carrier [+ 4 isozymes] ser [+ 2 isozymes] [+ 2 isozymes] phosphoenol [+ 3 isozymes] [+ 3 isozymes] 7-(methylthio)-2- 2-hydroxy- D-hexose 6- a (2E)-octadec- trehalose trehalose biosynthesis I : glmS decaprenyl-pyrophosphoryl- BUE88_RS05515 an (S)-2- icosapentaenoyl- acetaldehyde gly DNA without pyrF 6 bifunctional 3-phosphate + 6-oxohepta- 2-oxovalerate protein dimer]-N - guanosine a halide anion H NADH FMN pyruvate stearate oxoheptanoate phosphate UMP 2-enoyl-[acp] biosynthesis V D-glucosamine purine-nucleoside metallophosphatase/ UDP (N-acetylglucosamine)-N- DMK-12 hydroxycarboxylate CoA lesion a (2E,11Z)-icosa- carboxybiotinyl-L-lysine pppGpp 2-deoxy-D-ribose 2,4-dienoate α 6-phosphate UDP-α-D-glucose phosphorylase: 5'-nucleotidase: acetylmuramyl-(pentapeptide) 2,11-dienoyl-[acp] a trans-2- a glycogen D-glucopyranose 6-phosphate UDP- -D-glucose 5-phosphate a 2,3,4-saturated BUE88_RS04770 purine-nucleoside enoyl-[acyl- bifunctional (p)ppGpp alpha,alpha-trehalose- phosphoglucosamine biosynthesis I BUE88_RS06935 fatty acyl-[acp] isoamylase: phosphorylase: an all-trans- a dimer of carrier protein] synthetase/guanosine- phosphate synthase mutase: an (S)-2- D-firefly (5Z)- 3-[(5'-methylthio) an organic guanosine 3'- glgX D-glucopyranose deoxyribose- BUE88_RS04770 2-carboxy-1,4- glycerophosphoglycerol methyl red leukotriene-D4 H O L-cysteate pyrazinamide citrate 3',5'-bis(diphosphate) 3'- hypoxanthine xanthosine polyisoprenyl halocarboxylate non-adjacent L-cystathionine luciferyl-CoA 2 tetradecenoyl-CoA diphosphate 5'- (UDP-forming): otsA BUE88_RS09935 6-phosphate phosphate dGTP naphthoquinol pentyl]malate hydroperoxide a stearoyl-[acp] a maltodextrin alpha-D-glucose diphosphate HAD family glycerophosphodiester FMN-dependent thymidines in DNA membrane acyl-CoA acyl-CoA aspartate pyrophosphohydrolase: α,α-trehalose 6-phosphate D-glucosamine 1,4-dihydroxy- cystathionine 3-isopropylmalate peroxiredoxin: aconitate triphosphate 3'- aldolase: guanine deoxyguanosinetriphosphate deoxyribodipyrimidine amidase: BUE88_RS02025 phosphate-specific hydrolase: phosphodiesterase: NADH- dipeptidase: thioesterase: dehydrogenase: aminotransferase: a gondoyl-[acp] diphosphatase: malto- 1-phosphate BUE88_RS16060 triphosphohydrolase: 2-naphthoate beta-lyase: dehydrogenase: BUE88_RS12825 hydratase trehalose- phosphoglucomutase: BUE88_RS09080 BUE88_RS09755 azoreductase: photo-lyase: BUE88_RS06095 BUE88_RS14115 BUE88_RS15605 BUE88_RS09570 BUE88_RS03345 BUE88_RS02025 oligosyltrehalose UDP-N- hypoxanthine purine-nucleoside BUE88_RS00410 polyprenyltransferase: BUE88_RS02080 BUE88_RS04215 [+ 3 isozymes] AcnA: acnA acyl-CoA hydrolysis phosphatase: otsB BUE88_RS14865 deoxyribose- sn-glycerol BUE88_RS18455 BUE88_RS05670 long-chain fatty synthase: treY α-D-glucopyranose hydroxylase: phosphorylase: BUE88_RS05515 [+ 4 isozymes] glycerol leukotriene-E4 gly [+ 3 isozymes] [+ 6 isozymes] 8-(methylthio)- [+ 3 isozymes] pyrazine-2- acetylglucosamine phosphate 2'-deoxyguanosine PPP an (S)-2- 3-phosphate N,N'-dimethyl-p- L-homocysteine pyruvate (2E,5Z)- an alcohol D-threo-isocitrate i a thymine in DNA acid activation α α 1-phosphate BUE88_RS06820 BUE88_RS04770 DMKH a halide anion anthranilate D-firefly luciferin 2-oxooctanoate 3-sulfopyruvate carboxylate stearate a 2,3,4-saturated a maltooligosyl- , -trehalose diphosphorylase/ aldolase: deoC 2 hydroxycarboxylate phenylenediamine tetradecenoyl-CoA GTP ppGpp a long-chain fatty acyl CoA trehalose glucosamine-1- UTP--glucose- acyl-CoA long-chain fatty fatty acid malto- phosphate N- 1-phosphate xanthine long-chain fatty thioesterase: acetaldehyde D-glyceraldehyde 3-phosphate acid--CoA ligase: oligosyltrehalose acetyltransferase: uridylyltransferase: 2-amino-6-[1-hydroxyethyl]- all-trans- an apo-[LYS2 L- 2,3-bis-O- D-gluconate (5Z)- a supercoiled acid--CoA ligase: BUE88_RS18490 nucleoside- superpathway of pyrimidine deoxyribonucleosides degradation xanthine:NAD+ 2-carboxy-1,4- an all-trans-retinyl ester D-threo-isocitrate an acyl-CoA H O cis-vaccenoyl-CoA reduced riboflavin acetoacetate deacetylmycothiol BUE88_RS18710 trehalohydrolase: trehalose biosynthesis IV glmU galU 7-methyl-7,8-dihydropterin tridecaprenyl 2-aminoadipyl- coenzyme A (geranylgeranyl) cys L-homocysteine 6-phosphate 2 dodecenoyl-CoA duplex DNA BUE88_RS07510 [+ 3 isozymes] diphosphate GDP oxidoreductase: naphthoquinol CTP [+ 2 isozymes] a 2,3,4-saturated treZ N-acetyl-α-D- diphosphate carboxylesterase/ carrier-protein] isocitrate lyase/ -sn-glycerol cystathionine 6-phosphogluconate acyl-CoA acyl-CoA flavin reductase: acyl-CoA helicase: acetoacetate mycothiol kinase: pyrophosphokinase: bifunctional (p)ppGpp α 2'-deoxycytidine 2-amino-4-hydroxy-6- 1,4-dihydroxy- holo-ACP synthase: [+ 2 isozymes] UDP- -D-glucose BUE88_RS06820 lipase family protein: phosphoenolpyruvate 1-phosphate thioesterase: dehydrogenase: dehydrogenase: a long-chain fatty acid synthetase/guanosine- α glucosamine hydroxymethyldihydropteridine 2-naphthoate CDP-archaeol beta-synthase: dehydrogenase BUE88_RS05695 BUE88_RS09195 decarboxylase: synthase: stearoyl-CoA BUE88_RS17300 BUE88_RS02025 α,α-trehalose -maltose BUE88_RS09915 fatty acyl-CoA 1-phosphate BUE88_RS08135 a holo-[LYS2 L- mutase family protein: synthase: BUE88_RS05265 (decarboxylating): gnd BUE88_RS14115 BUE88_RS15605 BUE88_RS15605 BUE88_RS03390 mshD 3',5'-bis(diphosphate) 3'- maltose alpha-D- acetyl-CoA cytidine deaminase: urate diphosphokinase: folK polyprenyltransferase: [+ 3 isozymes] [+ 6 isozymes] [1-(2-amino-7-methyl-4-oxo- [+ 4 isozymes] 2-aminoadipyl- 3',5'-ADP BUE88_RS16175 [+ 3 isozymes] [+ 6 isozymes] [+ 6 isozymes] pyrophosphohydrolase: glucosyltransferase: treS UDP-N- BUE88_RS05515 unsaturatedBUE88_RS03785 L-cystathionine D-ribulose a single BUE88_RS04795 (2E,11Z)- riboflavin (2E,5Z)- acetone mycothiol PRPP biosynthesis I 7,8-dihydro-3H-pteridin- a fatty acid all-trans-retinol carrier-protein] succinate glyoxylate 5-phosphate a carboxylate BUE88_RS02025 maltose alpha-D- acetylglucosamine DMKH2-13 CDP-archaeol stranded DNA thymidine 6-yl)]ethyl diphosphate octadecenoyl-CoA dodecenoyl-CoA glucosyltransferase: treS diphosphorylase/ 2'-deoxyuridine GDP D-ribose 5- α,α-trehalose glucosamine-1- thymidine phosphate phosphate N- ribose-phosphate phosphorylase: 4-hydroxy-2- a β-D-mannoside a peptidoglycan a lipid II an acyl- a peptide with a L-threo-3- a dipetide with an N- (indol-3-yl) phosphoenol acetyltransferase: UDP-α-D- pyrophosphokinase: BUE88_RS04790 3,4-dihydroxyphenylacetate coenzyme A nonenal-[Cys- oxaloacetate a uridine in tRNA Ins(2)P ferroheme o (S)-malate uracil phosphorylase: terminal L-aspartate acetamide pyruvate UTP and CTP dephosphorylation I beta-mannosidase: peptidoglycan carrier protein leader sequence phenylserine glmU galactose BUE88_RS15745 signal peptidase I: low specificity L- peptidase E: Gly] conjugate 4-carboxy-4-hydroxy- tRNA malate:quinone BUE88_RS04790 thymine 3,4-dihydroxyphenylacetate BUE88_RS13985 glycosyltransferase: holo-ACP synthase: aminopeptidase amidase: inositol heme A synthase: pyruvate biosynthesis PRPP BUE88_RS06445 BUE88_RS12955 2-oxoadipate dihydrouridine UDP-N- BUE88_RS09915 threonine aldolase: N: pepN monophosphatase: oxidoreductase: UTP 2,3-dioxygenase: hpaD beta-mannosidase: BUE88_RS18770 [+ 2 isozymes] 4-hydroxy-2- aldolase/oxaloacetate synthase DusB: BUE88_RS03345 BUE88_RS02495 kinase: pyk acetylglucosamine UDP-α-D-glucose di-trans,octa-cis [+ 3 isozymes] BUE88_RS04060 BUE88_RS05455 BUE88_RS05170 Nucleoside and Nucleotide Biosynthesis 2-hydroxy-5- BUE88_RS18115 acyl-carrier protein 3',5'-ADP a proteinogenic gly nonenal-[L- decarboxylase: ligK BUE88_RS00405 pyrophosphorylase: UDP-glucose -undecaprenyl a peptidoglycan a leader sequence a peptide gly benzaldehyde asp CTP synthase: uracil carboxymethylmuconate a non glycosylated β-D- amino acid Cys] conjugate a 5,6-dihydrouridine (indol-3-yl)acetate myo-inositol ferroheme a oxaloacetate pyruvate BUE88_RS16520 4-epimerase 2-deoxy-α-D-ribose 1-phosphate diphosphate pyruvate BUE88_RS08675 semialdehyde sugar acceptor mannopyranose in tRNA superpathway of guanosine UDP-N-acetyl- GalE: galE superpathway of pyrimidine deoxyribonucleoside salvage superpathway of 5-aminoimidazole adenine and adenosine salvage III superpathway of pyrimidine nucleotides de novo biosynthesis I inosine-5'-phosphate biosynthesis I superpathway of adenosine pyrimidine deoxyribonucleotides α-D-glucosamine UDP-α-D-galactose UMP ribonucleotide biosynthesis CTP nucleotides de novo biosynthesis I de novo biosynthesis I nucleobases salvage bifunctional an α(1,5)- a double-stranded cytidine 2'-deoxycytidine quinoxaline-2- ethylnitronate [EntF L-seryl- a colanic acid lipid A-core uracil methylmalonate semialdehyde acyl-carrier protein coenzyme A thr DMK-12 L-arabinan propanoyl-CoA wound RNA Ins(1)P propionamide oxaloacetate AIR UDP CTP PRPP metallophosphatase/ oligonucleotide cytidine IMP adenine 2-deoxy-D-ribose 5-phosphate carboxyl adenylate 2-nitropropane carrier protein] O-antigen uracil 5'-nucleotidase: methylmalonate- demethylmenaquinone alpha-L- acetyl-/propionyl- IMP asp cytidine deaminase: amidophosphoribosyltransferase: purine-nucleoside acyl carrier protein: holo-ACP synthase: low specificity L- inositol deaminase: 5-(carboxyamino)imidazole phosphoribosyltransferase: semialdehyde dioxygenase: ligase domain- arabinofuranosidase: oligoribonuclease: CoA carboxylase RNA helicase: amidase: citrate synthase: CMP BUE88_RS06935 BUE88_RS00500 threonine aldolase: methyltransferase: monophosphatase: BUE88_RS04795 IMP ribonucleotide synthase: BUE88_RS04795 BUE88_RS14575 phosphorylase: BUE88_RS07655 BUE88_RS09915 containing protein: BUE88_RS16910 BUE88_RS02235 BUE88_RS03345 BUE88_RS16315 dUDP CDP 5-phospho-β- BUE88_RS05655 deoxyribose- dehydrogenase (CoA a quinoxaline-2- a holo-[EntF BUE88_RS05490 BUE88_RS06675 subunit alpha: BUE88_RS04770 bifunctional uridine [unspecified BUE88_RS04060 BUE88_RS05455 dehydrogenase: BUE88_RS04685 adenylosuccinate dCMP acylating): mmsA 3',5'-ADP L-seryl-carrier BUE88_RS04540 α-L- BUE88_RS04750 uridine 2'-deoxyuridine nucleoside- D-ribosylamine bifunctional pyr operon phosphate aldolase: AMP carboxyl-[aryl- degradation nitrite acetaldehyde gly acetaldehyde a nucleoside 5'- BUE88_RS09840 adenosine metallophosphatase/ menaquinol-12 (S)-methylmalonyl- an unwound RNA propanoate citrate synthase: BUE88_RS16060 H + NADH hydrogencarbonate propanoyl-CoA carrier protein] protein] E. coli M arabinofuranose myo-inositol N5-CAIR cytidylate kinase: cmk diphosphate kinase: phosphoribosylamine- transcriptional regulator/uracil 5'-nucleotidase: products] LPS monophosphate IMP BUE88_RS14350 purine ribonucleosides degradation CoA thymidine kinase: BUE88_RS17300 -glycine ligase: phosphoribosyltransferase deoxyribose-phosphate dehydrogenase: dCDP adenosine BUE88_RS06935 5-(carboxyamino)imidazole BUE88_RS05145 dCDP BUE88_RS14555 deaminase: PyrR: BUE88_RS02850 aldolase: deoC BUE88_RS16660 adenylo-succinate dUTP nucleoside- cytidine ribonucleotide mutase: purE UMP UDP-N-acetyl-α-D-muramoyl- a double thymidine kinase: thymidine BUE88_RS04785 [EntB aryl- an N-modified (S)-4-amino-5- a (1->4)-α-D-glucan a [protein] (L-serine/L- nucleoside-diphosphate dUTP diphosphatase: diphosphate kinase: GAR adenosine D-alanyl-D-alanine isovalerate coenzyme A a tRNA glu DMKH2-13 5-aminolevulinate (R)-NADPHX pyruvate adenylosuccinate BUE88_RS21005 cytidylate kinase: cmk L-alanyl-γ-D-glutamyl-L-lysine 4'-phosphopantetheine ATP threonine) phosphate biotin stranded DNA XMP asp kinase: BUE88_RS17300 BUE88_RS17300 acetaldehyde D-glyceraldehyde 3-phosphate carrier protein] aminoacyl-[tRNA] oxopentanoate ATP CAIR lyase: BUE88_RS21135 UDP-N-acetylmuramoyl- acetate--CoA aminoacyl-tRNA glutamyl-tRNA demethylmenaquinone 1,4-alpha-glucan porphobilinogen DNA gyrase NAD(P)H-hydrate pyruvate inosine UMP kinase: holo-ACP synthase: protein BUE88_RS13295 thymidine kinase: dCTP [+ 2 isozymes] dCTP adenosine tripeptide--D-alanyl- pantetheine-phosphate ligase: acs hydrolase: reductase: methyltransferase: branching enzyme: biotin--[acetyl-CoA- synthase: subunit A: epimerase: carboxylase: dUMP BUE88_RS03795 BUE88_RS09915 phosphatase: xanthosine-5'- BUE88_RS05145 pyrimidine deoxyribonucleotides deaminase: D- alanine ligase: adenylyltransferase: BUE88_RS03745 carboxylase] ligase: phosphoribosylaminoimidazolesuccinocarboxamide dUMP purine-nucleoside a holo-[EntB aryl- BUE88_RS15865 BUE88_RS11950 BUE88_RS05490 BUE88_RS03070 BUE88_RS12000 BUE88_RS11475 BUE88_RS09270 BUE88_RS18700 UDP BUE88_RS03970 3',5'-ADP an uncharged an L-glutamyl- a (1,6)-α-D-glucosyl- BUE88_RS04710 phosphate:L- thymidine kinase: dephosphorylation BUE88_RS04785 BUE88_RS18780 isovaleryl-CoA AMP diphosphate an N-modified biotinyl-5'- a negatively synthase: BUE88_RS14550 AMP thymidylate synthase: FGAR phosphorylase: UDP-N-acetyl-α-D-muramoyl-L-alanyl- carrier protein] Glu glutamine thymidylate synthase: NTP 3'-dephospho-CoA amino acid tRNA [tRNA ] menaquinol-13 (1,4)-α-glucan a [protein] Ser/Thr porphobilinogen (S)-NADPHX oxaloacetate BUE88_RS21005 nucleoside-diphosphate acetyl-CoA adenylate supercoiled DNA BUE88_RS19115 BUE88_RS19115 BUE88_RS04770 γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine amido-ligase phosphoribosylformylglycinamidine pyrophosphohydrolase: xanthosine adenosine inosine guanosine thymidylate synthase: kinase: BUE88_RS17300 (AMP-forming): SAICAR adenylate kinase: thymidylate synthase: synthase subunit PurL: BUE88_RS11945 BUE88_RS17630 xanthine and hypoxanthine UTP BUE88_RS09770 BUE88_RS17630 dCTP dCMP BUE88_RS10035 xanthosine salvage BUE88_RS14435 a single- α-D- (2R,3S)-3- an N-acylated- 3-sulfocatechol sec 4-methylcatechol DMKH chorismate methylglyoxal nicotinamide adenylosuccinate CTP synthase: an N-formyl-L-methionylaminoacyl-tRNA DL-allothreonine VibB coenzyme A a tRNA ser 2 dTMP [+ 2 isozymes] purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside stranded RNA glucopyranose ATP isopropylmalate lyase: BUE88_RS13295 polyribonucleotide D-amino acid catechol 2,3- GMP hypoxanthine BUE88_RS08675 dUTP diphosphatase: serine N-acyl-D-amino- catechol 2,3- demethylmenaquinone 3-isopropylmalate glyoxalase: ADP phosphorylase: phosphorylase: phosphorylase: phosphorylase: peptide deformylase: holo-ACP synthase: 1-phosphate serine--tRNA ligase: dTMP kinase: xanthosine FGAM phosphoribosyltransferase: hpt nucleotidyltransferase: glucose-1-phosphate dioxygenase: chorismate mutase: nicotinamidase: CTP BUE88_RS21135 BUE88_RS04770 BUE88_RS04770 BUE88_RS04770 BUE88_RS04770 BUE88_RS18705 hydroxymethyltransferase: BUE88_RS09915 acid deacylase: BUE88_RS07180 dioxygenase: methyltransferase: dehydrogenase: BUE88_RS05830 AICAR pyrimidine BUE88_RS05075 S-methyl-5'-thioadenosine BUE88_RS17585 BUE88_RS08365 BUE88_RS14415 BUE88_RS05030 purine-nucleoside [+ 2 isozymes] BUE88_RS09515 BUE88_RS02350 adenylyltransferase: (2Z,4E)-2- an L-seryl- BUE88_RS08365 BUE88_RS05490 BUE88_RS04215 [+ 9 isozymes] guanylate kinase: peptide deformylase: def a nucleoside a single- a holo-[VibB aryl- nucleobases salvage II dTMP kinase: tmk phosphoribosylformylglycinamidine dUTP dUMP degradation II α-D-ribose- 3',5'-ADP BUE88_RS02425 sec BUE88_RS02815 bifunctional dTMP phosphorylase: IMP formate a L-methionylaminoacyl-tRNA gly acetaldehyde carrier protein] a carboxylate a D-amino acid sulfite hydroxyhexa- [tRNA ] 2-hydroxy-5-methyl-6- 4-methyl-2- F0F1 ATP ADP reductase: cyclo-ligase: BUE88_RS14580 diphosphate stranded RNA ADP-α-D-glucose MQH prephenate (R)-lactate nicotinate phosphoribosylaminoimidazolecarboxamide cytosine dTDP BUE88_RS04770 S-methyl-5'- 1-phosphate 2,4-dienedioate oxohexa-2,4-dienoate 2 oxopentanoate synthase BUE88_RS19100 dTMP kinase: xanthine formyltransferase/IMP cytosine deaminase: thioadenosine α-D-ribose 1,5- nucleoside- AIR guanine and guanosine salvage 5-hydroxy-CTP 5-hydroxy-CMP 5'-methylthioadenosine GDP subunit BUE88_RS05075 cyclohydrolase PurH: purH BUE88_RS06850 diphosphate kinase: adenine and phosphomutase: epsilon: dTMP kinase: tmk phosphorylase: a [glycine-cleavage lipid II (meso 5-dehydro-2- a 2'- methyl β-D-glucoside [+ 2 isozymes] adenosine salvage I BUE88_RS04765 orotidine 5'- coenzyme A NADP + FMN NAD(P)H H + a kanamycin an L-cysteinyl- D-glucopyranose 5-methylcytosine α-amylose acetamide BUE88_RS17300 BUE88_RS14925 SAM complex H protein] a sulfurated [sulfur carrier] diaminopimelate deoxy-D-gluconate deoxyribonucleoside [DNA] 6-phosphate FAICAR atpC dADP uracil phosphate [tRNA Cys ] dTDP D-ribose 5- 6 6-phospho-beta- dTTP guanosine 5-MTR-1-P N -octanoyl-L-lysine containing) peptidoglycan orotate CoA-disulfide 5-dehydro-2- 5'-triphosphate flavin reductase: aminoglycoside aminoacyl-tRNA cytosine 1,4-alpha-glucan nucleoside- GDP reductase: [+ 7 isozymes] lipoyl RNA-directed xylose isomerase: bifunctional nucleoside-diphosphate uracil purine-nucleoside phosphate reductase: deoxygluconokinase: BUE88_RS05695 glucosidase: phosphotransferase: branching enzyme: amidase: nucleoside- adenosine glycosyltransferase: phosphoribosyltransferase: DNA polymerase: hydrolase: deaminase: diphosphate BUE88_RS19100 XMP synthase: lipA BUE88_RS16635 BUE88_RS15700 BUE88_RS03345 phosphoribosylaminoimidazolecarboxamide kinase: BUE88_RS17300 phosphoribosyltransferase: CMP phosphorylase: a [glycine-cleavage BUE88_RS18770 BUE88_RS14185 BUE88_RS15030 iolC [+ 2 isozymes] BUE88_RS08065 BUE88_RS15865 BUE88_RS06850 BUE88_RS03745 kinase: diphosphate purine-nucleoside an unsulfurated lipid II (meso di-trans,octa-cis BUE88_RS00785 β-D-glucose 5'-deoxyadenosine met complex H protein] + + formyltransferase/IMP BUE88_RS05655 phosphorylation BUE88_RS04770 H NADPH CoA-disulfide 5-dehydro-2-deoxy-D- NAD(P) FMNH MeOH a kanamycin Cys [+ 2 isozymes] ATP kinase: dTTP phosphorylase: [sulfur carrier] diaminopimelate -undecaprenyl orotate PRPP [DNA] 2 a tRNA cys keto-D-fructose amylopectin BUE88_RS17300 guanine N 6 -lipoyl-L-lysine 6-phosphate acetate cyclohydrolase PurH: purH BUE88_RS17300 bifunctional pyr operon gluconate 6-phosphate 3'-phosphate thymine dGDP CMP BUE88_RS04770 containing) diphosphate transcriptional regulator/uracil cytidylate adenine Carbohydrate Degradation phosphoribosyltransferase IMP dATP kinase: cmk hypoxanthine α GTP nucleoside- 10 phosphoenol an [HPr]- RNase III mRNA p-nitrophenyl- -L- a [protein]- an organic N-acetyl-D- a monocarboxylic a glucosylated aldehydo-D- PyrR: BUE88_RS02850 CDP adenine phosphoribosyltransferase: hpt an N - an L-methionyl- hesperidin H + malonyl-CoA 5-fluorocytosine (R)-lactate diphosphate D-galactose degradation I (Leloir pathway) Met pyruvate L-histidine processing rhamnopyranoside L-cysteine hydroperoxide a tRNA precursor mannosamine acid amide glycogenin galacturonate phosphoribosyltransferase: chitin degradation II (Vibrio) formyltetrahydrofolate [initiator tRNA ] alpha-L- kinase: UMP nucleoside- L-rhamnose degradation I L-arabinose phosphoenolpyruvate- substrate alpha-L- peroxiredoxin: type III polyketide N-acetylneuraminate 1,4-alpha-glucan cytosine glucuronate BUE88_RS01960 methionyl-tRNA ribonuclease III: ribonuclease D: D-2-hydroxyacid BUE88_RS17300 diphosphate degradation I -protein rhamnosidase: rhamnosidase: BUE88_RS12825 synthase: synthase: amidase: branching enzyme: isomerase: GMP β formyltransferase: fmt BUE88_RS01130 deaminase: dehydrogenase: -D-galactose α-L- an N-formyl- phosphotransferase: ptsP BUE88_RS03955 BUE88_RS06340 BUE88_RS06340 BUE88_RS03345 kinase: chitin RNase III [+ 2 isozymes] BUE88_RS16610 BUE88_RS16940 BUE88_RS03745 BUE88_RS06850 BUE88_RS15800 BUE88_RS11330 AMP rhamnopyranose L-arabinopyranose an [HPr protein]- β-L- hesperitin-7-O- β-L- an intra- a nucleoside 5'- dGTP BUE88_RS17300 galactose L-methionyl- a tetrahydrofolate π an mRNA fragment processing a tRNA N-acetyl-β- L-rhamnose N -phospho- pyruvate β 4-nitrophenol an alcohol monophosphate octoketide a glycogen [+ 2 isozymes] D-tagaturonate chitinase: L-arabinose [initiator tRNA met ] rhamnopyranose -D-glucoside rhamnopyranose protein disulfide a monocarboxylate pyruvate mutarotase: mutarotase: product mRNA neuraminate 5-fluorouracil CTP BUE88_RS17165 isomerase: L-histidine BUE88_RS17385 BUE88_RS06305 BUE88_RS06545 α L-rhamnose a chitodextrin L-ribulose -D-galactose an N-acetyl-β- salicin 6- a (1->4)- a (1->4)- 5-amino-4- 2+ an (L-cysteinylglycine) mutarotase: PRPP isobutanoate a ribonucleic acid rutin protoporphyrin IX Mg Asx glycerol 2-deoxy-D-ribose L-idonate imidazolecarboxyamide D-hexosaminide phosphate -S-conjugate α-D-glucan a tRNA asp α-D-glucan galactokinase: BUE88_RS08980 beta-N- 6-phospho-beta- β-L- adenine acetate--CoA ribonuclease PH: alpha-L- magnesium aminopeptidase 1,4-alpha-glucan aspartate-- glycerol 1,4-alpha-glucan L-idonate 5- galK acetylhexosaminidase: glucosidase: ribokinase: rhamnopyranose phosphoribosyltransferase: ligase: acs BUE88_RS16550 rhamnosidase: chelatase: N: pepN branching enzyme: tRNA(Asn) ligase: dehydrogenase: branching enzyme: dehydrogenase: L-ribulose 5- BUE88_RS14080 BUE88_RS16635 BUE88_RS13080 L-rhamnose a chitodextrin BUE88_RS01960 a nucleoside BUE88_RS06340 BUE88_RS07040 an L-cysteine- BUE88_RS03745 BUE88_RS05585 BUE88_RS09275 BUE88_RS03745 BUE88_RS11275 α-D-galactose phosphate an N-acetyl-β- a ribonucleic acid β-L- quercetin- β-D-glucose Mg- gly UDP-α-D-glucose isomerase: isobutanoyl-CoA AMP diphosphate diphosphate S-conjugate an L-aspartyl- 2-deoxy-D-ribose 1-phosphate AICAR an alcohol salicyl alcohol a GlgE-glycogen dihydroxyacetone a glycogen 5-dehydro- D-hexosamine rhamnopyranose 3-glucoside 6-phosphate protoporphyrin [tRNA Asx ] rhaI L-ribulose-5- 5-phosphate D-gluconate phosphate 4- keto-L-rhamnulose epimerase: BUE88_RS06550 sn-glycero-3- arbutin-6- a (1->4)- beta-N- a dimer of non-adjacent 2'- a single a ribonucleoside chitin naringin a chitodextrin α-D-ribofuranose L-idonate 2-succinylbenzoate coenzyme A asp fumarate a steryl-ester ergosteryl oleate α acetylhexosaminidase: D-xylulose deoxycytidine and thymidine in DNA phosphoethanolamine stranded DNA triphosphate phosphate -D-glucan deoxyribodipyrimidine glycerophosphodiester o-succinylbenzoate- beta-N- 6-phospho-beta- alpha-L- cholesterol cholesterol 1,4-alpha-glucan L-idonate 5- N,N'- BUE88_RS14080 N,N',N''- 5-phosphate DNA primase: L-aspartate chitinase: ribokinase: photo-lyase: phosphodiesterase: -CoA ligase: acetylhexosaminidase: glucosidase: rhamnosidase: esterase: esterase: branching enzyme: dehydrogenase: L-rhamnulofuranose diacetylchitobiose triacetylchitotriose BUE88_RS00415 oxidase: nadB BUE88_RS17165 BUE88_RS13080 BUE88_RS05670 BUE88_RS09755 BUE88_RS05520 ssDNA/pppN(pN) BUE88_RS14080 BUE88_RS16635 BUE88_RS06340 BUE88_RS04355 BUE88_RS04355 BUE88_RS03745 BUE88_RS11275 beta-N- sn-glycerol 4-(2'-carboxyphenyl) N-acetyl-D- β-D-glucose β-L- succinate 2-iminosuccinate a thymine in DNA a cytosine in DNA ethanolamine hybrid chitin hydroquinone prunin a sterol a fatty acid oleate ergosterol N,N'- α-D-ribose 5-dehydro- acetylhexosaminidase: 3-phosphate -4-oxobutyryl-CoA n -1 glucosamine 6-phosphate rhamnopyranose starch diacetylchitobiose 5-phosphate D-gluconate BUE88_RS14080 L-rhamnulose N-acetyl-D- chitobiose degradation 1-phosphate glucosamine D-cellobiose 7,8- a 5'-phospho- UTP a peptide with L-gulono- acetoacetyl-CoA H O acetyl-CoA dioscin an [RNA]- quercitrin canavaninosuccinate O chloride lanosteryl oleate acetylxylan xylitol bifunctional N,N'- 2 ribonucleoside- 2 an N-terminal UDP-glucose:α- 6'-phosphate dihydromonapterin 3'-hydroxyl NTP 1,4-lactone rhamnulose- diacetylchitobiose hydroxymethylglutaryl-CoA alpha-L- 6-phospho-beta- dihydroneopterin [RNA] alpha-L- argininosuccinate chlorite dismutase: cholesterol L-alanine acetylxylan erythritol/L-threitol D-galactose- UDP-glucose RNA ligase (ATP) pyrophosphohydrolase: aminopeptidase 1-phosphate 6'-phosphate synthase: BUE88_RS07590 rhamnosidase: glucosidase: aldolase: folB rhamnosidase: lyase: argH BUE88_RS11980 esterase: esterase: dehydrogenase: gluconolactonase: 1-phosphate 4-epimerase : BUE88_RS20505 BUE88_RS11945 N: pepN aldolase/ xylose degradation I BUE88_RS06340 BUE88_RS16635 6-(hydroxymethyl) BUE88_RS06340 BUE88_RS04355 BUE88_RS15690 BUE88_RS06250 BUE88_RS12700 uridylyltransferase: GalE: galE N-monoacetylchitobiose HMG-CoA β glycolaldehyde β fumarate L-canavanine chlorite short-chain 3-O- -D-glucosyl- D-glucopyranose -7,8-dihydropterin a ribonucleic acid -L- UMP a peptide ala galT L-rhamnopyranose D-glucopyranose quercetin oleate lanosterol acetate xylan D-xylulose α-D-glucopyranose dehydrogenase: 6'-phosphate diosgenin 6-phosphate rhamnopyranose L-gulonate UDP-α-D-galactose D-xylopyranose 1-phosphate BUE88_RS06350 6-phospho-beta- xylose isomerase: glucosidase: BUE88_RS15700 alpha-D-glucose (S)-lactaldehyde DHAP BUE88_RS16635 phosphate-specific D-xylulose N-acetyl-D- D-mannose phosphoglucomutase: glucosamine D-glucosamine degradation xylulose kinase: BUE88_RS14865 6-phosphate BUE88_RS15695 D-mannopyranose D-glucopyranose D-xylulose 6-phosphate fructose degradation 6-phosphate mannose-6- 5-phosphate phosphate β-D-fructofuranose isomerase, 1-phosphate 1-phosphofructokinase: class I: manA BUE88_RS10725 F6P 1-phosphofructokinase: BUE88_RS14070 β-D-fructose 1,6- bisphosphate a branched- chain an amino L-ascorbate amino acid (2-aminoethyl) acid 6-phosphate molybdate N-acetyl-α-D- 1-(β-D phosphonate an amino an amino an amino an amino an amino a carbohydrate a carbohydrate an inorganic D-glucose 6- 3,5- glycine betaine glucosamine lactose 6'- a C4- a sugar 6- a sugar 6- sn-glycerol ribofuranosyl) a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a nucleotide a polysaccharide anion phosphate D-galactose dimethoxytoluene L-proline betaine phosphate dicarboxylate phosphate phosphate acid acid acid acid acid a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate 3-phosphate cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA 6-phosphate predicted nicotinamide predicted ABC predicted predicted predicted ABC PEP-driven transporter ABC predicted ABC predicted ABC ABC transporter of RS07440 GrpE transporter RS05565 RS13375 RS05840 RS00465 RS17245 RS13385 RS14075 RS15125 of a RS13380 RS02115 RS05285 RS10420 RS18370 RS10425 transporter RS00855 RS06335 RS11185 RS08275 RS14060 RS16640 RS05350 RS12950 transporter of RS15395 RS12505 RS06580 RS07435 RS08045 RS09620 transporter of RS05725 RS13825 RS17150 RS17950 RS08175 RS07125 RS06690 RS08990 RS15570 RS00745 RS03335 RS09290 RS06425 RS16745 RS07510 RS18710 transporter (2-aminoethyl) of L- branched- of an a carbohydrate a carbohydrate of molybdate phosphonate ascorbate α chain amino acid an inorganic 3,5- glycine betaine N-acetyl- -D- a C4- 1-(β-D a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a polysaccharide a nucleotide D-glucose D-galactose lactose amino acid a sugar a sugar an amino an amino an amino an amino an amino a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate sn-glycerol glucosamine ribofuranosyl) anion dimethoxytoluene L-proline betaine dicarboxylate 3-phosphate cis-vaccenate cis-vaccenate cis-vaccenate (2-aminoethyl) acid acid acid acid acid a carbohydrate a carbohydrate molybdate nicotinamide an amino L-ascorbate phosphonate a branched- acid chain amino acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.