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HIGHLIGHTS

50TH ANNIVERSARY inspirational people after their ideas more than three people, so would and dedication made 1953 a water- she have been honoured even had shed year in science? she been alive? Regardless, Franklin Francis Harry Compton Crick, the did become something of a feminist Whatever happened to... man who, at the age of 30, in his own icon after Watson was rather dismis- words “essentially knew nothing”,has sive of her in his bestseller of the late continued to address ‘big’ questions 1960s, . Her last since he and answered working years produced what one of the biggest. Collaborations Watson describes as “very beautiful with the 2002 Nobel laureate Sydney work” on the structure of tobacco Brenner produced ideas on mosaic virus. synthesis and the genetic code. Crick James Dewey Watson has joined the Salk Institute in California retained the high profile that he in 1976, and this has remained his gained after widespread recognition affiliation up to the present, where he followed on the heels of the 1953 has focused on the problem of con- breakthrough. After brief stints sciousness. Most recently, he has been working with Alexander Rich, and considering the neural correlates of Crick again, Watson went on to consciousness: the minimal set of Harvard where he collaborated with neuronal events that give rise to a Walter Gilbert. In 1968, he took over specific aspect of a conscious precept. as Director of Cold Spring Harbor Rosalind Elsie Franklin, often Laboratory, which he revitalized by characterized as the wronged hero- focusing on tumour biology, even- ine of the double helix story, died tually becoming its President in four years before Watson, Crick and 1994. In this role, as well as during a Winners of the 1962 Nobel Prizes display their diplomas. Maurice Watson and Crick are among the Wilkins received their stint at the National Institutes of Wilkins is on the far left, Francis most recognizable names in biology, in 1962. The Nobel rules preclude Health as Associate Director for Crick is third from the left and James Watson is second from the right. Wilkins and Franklin perhaps less posthumous awards, but they also Human Genome Research and © Bettmann/CORBIS. so, but what happened to these preclude prizes being shared by subsequently as Director of the

50TH ANNIVERSARY Watson had put together a model of the double helix. Consequently, DNA models feature in several celebratory events including the Watson-adorned DNA50 Twisting the night away events at the International Centre for Life (14–17 April, Newcastle, UK). Maurice Wilkins is also a man in demand DNA’s big anniversary has not been allowed in a historical and social context in this anniversary year, with appearances at to slip away with only a few geneticists (New York Public Library, 25 February– public events in Cambridge (‘Who Twists the raising a cheer: the public are also being 29 August). Helix?’,The University Centre, 17–19 March) involved. Some events are considerably less public: and London (‘DNA Past, Present and Future’, Celebrations got off to a serious start in the DNA gala dinner at the Waldorf Astoria King’s College, 22 April). the UK with a public forum on ‘ (28 February, New York) was an invite-only Anyone not able to attend these events and the Search for Safer Drugs’ (6 February, affair. Similarly, the flagship celebratory will still be able to get into the spirit of the Royal College of Physicians, London). dinner in the UK (23 April, Guildhall, celebration:‘National DNA Day’ (25 April) Science festivals in March (24–30, London) will have a restricted guest list, will be celebrated by high schools through- Wrexham) and April (17–22, Edinburgh, probably featuring the prime minister, out the USA, and in the UK a special DNA Scotland) promise to be more light-hearted, members of the royal family, Nobel laureates £2 coin will be a nice souvenir for any with DNA-based public lectures, discussion and, if guest of honour James Watson has his double helix buff. forums and interactive workshops. way, Michael Caine, Sean Connery and So, there is no excuse for the public not to Interaction is also a big part of Kew Garden’s soccer-star David Beckham! be involved in the party this year, and let us celebratory event ‘DNA in the Garden’ Watson, surely the busiest man in the hope that they do get involved because, as (29 March–11 May, London). world this year, has also been invited to Watson says,“DNA is for the world, not Double helix fever is also gripping the US, unveil a plaque at the Eagle public house just science”. particularly in New York, where numerous where famously declared to Nick Campbell organizations are taking part in a host of puzzled drinkers on 28 February 1953 activities under the DNA festival banner. ‘We have uncovered the secret of life’ References and links WEB SITE One exhibition promises to tell the story of (25 April, Cambridge, UK). Of course, Cold Spring Harbor Laboratory DNA anniversary site: New York and DNA, placing the discovery Crick’s exclamation came after he and http://www.dna50.org/main.htm

244 | APRIL 2003 | VOLUME 4 www.nature.com/reviews/genetics

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