PSYCHOTROPIC DRUG INDICATIONS (Part 1 of 2) Bipolar Disorder Mixed Generic Brand Form Mania Depression Episodes Maintenance MDD TRD PMDD Schizophrenia Others4 ATYPICAL ANTIPSYCHOTICS aripiprazole — tabs, ODT, oral soln √ √ √ √1 √ √ Abilify tabs √ √ √ √1 √ √ Abilify Maintena ext-rel IM inj √ √ Abilify Mycite tabs with sensor √ √ √ √1 √ aripiprazole lauroxil Aristada ext-rel IM inj √ Aristada Initio ext-rel IM inj √ asenapine Saphris sublingual tabs √ √ √ √ Secuado transdermal system √ brexpiprazole Rexulti tabs √1 √ cariprazine Vraylar caps √ √ √ √ clozapine Clozaril tabs √ √ Versacloz oral susp √ √ iloperidone Fanapt tabs √ lumateperone Caplyta caps √ lurasidone Latuda tabs √ √ olanzapine Zyprexa tabs √ √2 √ √ √2 √ IM inj √ Zyprexa Relprevv ext-rel IM inj √ Zyprexa Zydis ODT √ √2 √ √ √2 √ paliperidone Invega ext-rel tabs √ √ Invega Sustenna ext-rel IM inj √ √ Invega Trinza ext-rel IM inj √ pimavanserin Nuplazid tabs, caps √ quetiapine Seroquel tabs √ √ √1 √ Seroquel XR ext-rel tabs √ √ √ √1 √1 √ risperidone Perseris ext-rel SC inj √ Risperdal tabs, oral soln √ √ √ √ Risperdal Consta ext-rel IM inj √ √ Risperdal M-tabs ODT √ √ √ √ ziprasidone Geodon caps √ √ √1 √ IM inj √ COMBINATION ATYPICAL & SELECTIVE SEROTONIN REUPTAKE INHIBITOR olanzapine + fluoxetine Symbyax caps √ √ MONOAMINE OXIDASE INHIBITORS (MAOIs) phenelzine Nardil tabs √ selegiline EMSAM transdermal system √ tranylcypromine Parnate tabs √ SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITORS (SNRIs) desvenlafaxine — ext-rel tabs √ Pristiq ext-rel tabs √ duloxetine Cymbalta caps √ √ Drizalma Sprinkle del-rel caps √ √ levomilnacipran Fetzima ext-rel caps √ venlafaxine — scored tabs √ Effexor XR ext-rel caps √ √ SELECTIVE SEROTONIN REUPTAKE INHIBITORS (SSRIs) citalopram Celexa scored tabs √ escitalopram Lexapro scored tabs √ √ fluoxetine — tabs, oral soln √3 √ √3 √7 √ Prozac caps √3 √ √3 √ (continued) PSYCHOTROPIC DRUG INDICATIONS (Part 2 of 2) Bipolar Disorder Mixed Generic Brand Form Mania Depression Episodes Maintenance MDD TRD PMDD Schizophrenia Others4 SELECTIVE SEROTONIN REUPTAKE INHIBITORS (SSRIs) (continued) paroxetine Paxil scored tabs, oral susp √ √ Paxil CR controlled-rel tabs √ √ √ sertraline Zoloft scored tabs, oral conc √ √ √
SSRI AND 5-HT1A RECEPTOR PARTIAL AGONIST vilazodone Viibryd tabs √ SEROTONERGIC ANTIDEPRESSANT vortioxetine Trintellix tabs √ TETRACYCLIC ANTIDEPRESSANTS maprotiline HCl — tabs √ √ mirtazapine Remeron scored tabs √ Remeron Soltab ODT √ TRICYCLIC ANTIDEPRESSANTS (TCAs) amitriptyline — tabs √ amoxapine — tabs √ √ desipramine Norpramin tabs √ doxepin — caps, oral conc √ √ imipramine Tofranil tabs √ nortriptyline Pamelor caps √ protriptyline — tabs √ trimipramine — caps √ OTHER CLASSES brexanolone Zulresso IV infusion √ bupropion HBr Aplenzin ext-rel tabs √ √ bupropion HCl — tabs √ Forfivo XL ext-rel tabs √ Wellbutrin SR sust-rel tabs √ Wellbutrin XL ext-rel tabs √ √ carbamazepine Equetro ext-rel caps √ √ divalproex sodium Depakote del-rel tabs √ Depakote ER ext-rel tabs √ √ esketamine Spravato nasal spray √5,6 √5 haloperidol Haldol IM inj √ √ lamotrigine Lamictal scored tabs, chewable √ dispersible tabs ODT √ lithium carbonate — caps, tabs √ √ √ Lithobid ext-rel tabs √ √ lithium ion — oral soln √ √ √ nefazodone — scored tabs √ trazodone — scored tabs √ NOTES Key: conc = concentrate; del-rel = delayed release; ext-rel = extended-release; MDD = major depressive disorder; ODT = orally-disintegrating tabs; PMDD = premenstrual dysphoric disorder; susp = suspension; TRD = treatment resistant depression. 1For adjunctive treatment. 2 Use in combination with fluoxetine. 3Use in combination with olanzapine. 4Others include agitation due to bipolar/schizophrenia, anxiety, seasonal affective disorder, tourette’s, postpartum depression, schizoaffective disorder, Parkinson’s disease psychosis, others; see drug monograph or full labeling. 5Use in conjunction with an oral antidepressant. 6MDD with acute suicidal ideation or behavior 7Fluoxetine 10mg and 20mg tabs have indication for PMDD (formerly brand Sarafem). Not an inclusive list of medications and/or official indications. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling. (Rev. 7/2021)