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INCREASES SEROTONIN INHIBITS SEROTONIN INHIBITS SEROTONIN STIMULATES SEROTONIN SYNTHESIS TM RELEASE NUTRITIONAL SUPPLEMENTS AMPHETAMINES Introducing: MDMA ("ecstasy" or "mollie") Tru360Sibutramine 5-hydroxytryptophan MEDS, , OTHER SYMPATHOMIMETICS/ TruANESTHETICS Partnership. TruEletriptan Customization.* Tru Service.DextroamphetamineTM ACTIVATE SEROTONIN ANTIDEPRESSANTS, SSRI MDMA ("ecstasy" or "mollie") RECEPTORS * Escitaloprams ANTIDEPRESSANTS * ANXIOLYTICS * BuspironeTru360 is the most comprehensive, hospice-centered, AGENT Lysergic acid diethylamide (LSD) MAO INHIBITORSpatient-focused solution Sertralinein the market today. Tru360Levodopa MUSCLE RELAXANTS - drives sustained cost reduction while improving patient ANTIDEPRESSANTS, SNRI MIXED CENTRAL-ACTING Phenelzinesatisfaction and outcomes. Tru360 is built on fiveAGONIST-ANTAGONIST key Tedizolidcomponents that produceVenlafaxine excellent end-of-life care in a OPIOID / Alfentanil MAO-A INHIBITORScost-effective manner.ANTIDEPRESSANTS, ANTIMANIC AGENTS * * Meperidine OPIOID AGONISTS SEROTONIN/5HT2C MAO-B INHIBITORS * RECEPTOR Rasagiline Butorphano Codeine* Meperidine OTHER SEROTONIN EFFECTS MUSCLE RELAXANTS * PARTNERSHIP Metaxalone EFFICIENCYTrimipramine : SEROTONIN- Opium Real Collaboration. Powered by People. ,Intuitive SEROTONIN/5HT3 Workflow. Proactive Intervention. AGONISTS (SDAS) NUTRITIONAL SUPPLEMENTS Oxycodone* Driven by Data. Real Results. St. John's Wort () RECEPTOR ANTAGONISTS: Dihydrocodeine Hydrocodone RisperidoneWe build a custom service model to fit your Our technology provides proactive intervention, Hydromorphone workflow and your culture. Your Tru360 Team, streamlinesOndansetron* pharmacy interaction and Oxymorphonesaves up Iloperidoneincluding a dedicated pharmacist and account to $2,000 per nurse annually. HPS pharmacists Remifentanil manager, partner with you to manage saving’s are available 24/7 so you never wait for Sufentanilthe ANTIPSYCHOTICS:initiatives. MULTI-ACTING The result: sustained and ongoing ANTITUSSIVES,answers you NON-OPIOID need. We save you time, soTramadol you RECEPTOR - TARGETEDcost reduction (MARTA) to reinvest in growth – and canDextromethorphan focus on patient care. Clozapinewe’ll be there for you every step of the way. MUSCLE RELAXANTS, CENTRALLY-ACTING Cyclobenzaprine Asenaptine EDUCATION COMPLIANCEOPIOID AGONISTS Empowered Nurses. Seamless Onboarding. Compliant. Actionable. Ethical. Rapid Results. Meperidine HPS Methadoneis the Gold Standard for We provide industry news and resources reviews. Our CoPs-Compliant med reviews that affect you. Through CE Courses, our provideTapentadol a complete evaluation of medication webinar series, news articles, blog posts, history, detailed clinical insights with custom live presentations and our actionable recommendations, and much extensive resource library we empower more to ensure that you provide the right *Serotonin toxicity possible but may be less likely to occur your team to make the best decisions at medication to the right patient in the right the point of prescribing. form and dosage at the right time. BLUE FONTS ARE FREQUENTLY USED IN HOSPICE

Adapted from TOXEDNETWORK The Clinican’s Toxicology Resource http://toxed-ip.com/ToxEdView.aspx?id=596602, Clinical pharmacology of atypical antipsychotics: an update, Mauri, M.C. et.A al.; Custom EXCLI Journal Network. 2014 accessed Built for at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464358/#:~:text=Atypical%20antipsychotics%20with%20a%20 Hospice. Built forhigh,ziprasidone%%20iloperidone%2C%20lurasidone) You. ; Essential Psychopharmacology, second edition; Stahl, Stephen *Foong, A. et. al., Canadian Family Physician, October 2018 Volume 64: Demystifying (or serotonin toxicity) With 65,000 plus pharmacies in our network, we don’t force you into a one-size fits-all solution. HPS connects your hospice to a nationwide network of thousands of local delivery providers to ensure patients receive access to medications when they need them.

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