History of Cell Biology (PDF)

Date:

1. In bullet points, summarize how Antonie von Leeuwenhoek and Robert Hooke contributed to cell biology.

Antonie van Leeuwenhoek (1632 – 1723)

Antonie van Leeuwenhoek

Source: https://en.wikipedia.org/wiki/Antonie_ van_Leeuwenhoek#/media/File: Anthonie_van_Leeuwenhoek_(1632-1723). _Natuurkundige_te_Delft_Rijksmuseum_SK -A-957.jpeg

Robert Hooke (1635 – 1703)

Robert Hooke and Samuel Pepys

Source: https://commons.wikimedia.org/wiki/ File:7_Hooke_%26_Pepys.JPG

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2. As a scientist, Robert Brown not only made a name for himself by discovering Brownian motion, but he also played a part in developing cell biology. Check the correct box to indicate how he participated in gaining further knowledge on cells.

Robert Brown was the first to conduct microscopic observations.

Robert Brown was the first to draw sketches of the nucleus and cytoplasmic streaming.

Robert Brown was the first to describe the nucleus and cytoplasmic streaming.

Robert Brown (1773 – 1858) Robert Brown was the first to artificially produce a nucleus and cytoplasmic streaming. Source: https://commons.wikimedia.org/ wiki/File:Robert_Brown_(botanist).jpg

3. Write down the three tenets of cell theory.

Cell Theory: 1.

Matthias Schleiden (1804 – 1881) Theodor Schwann (1810 – 1882) Rudolf Virchow (1821 – 1902)

Source: https://commons.wikimedia.org/wiki/File: Source: https://commons.wikimedia.org/wiki/ Source: https://commons.wikimedia.org/wiki/ Matthias_Jacob_Schleiden.jpg File:TheodorSchwann.jpg File:Rudolf_Virchow_NLM3.jpg

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4. Many scientists contributed to the long process of developing today’s model of cell membranes. For the four major steps outlined below, give the names of the scientists most strongly associated with their achievement as well as the year in which they were made public.

• lipid molecules • proposal of a model • addition of protein • correction of tri- identified as major assuming the bi-layered layers to the bi-layered layered model and components of cell structure of cell model (tri-layered addition of membranes membranes model) integral proteins (fluid mosaic model)

© Jerome Walker Source: https://commons.wikimedia.org/wiki/File: Source: https://commons.wikimedia. Cell_membrane_detailed_diagram_en.svg#/ org/wiki/File: Fluid_Mosaic.svg#/ media/File:Cell_membrane_detailed_ media/File:Fluid_Mosaic.svg diagram_en.svg

5. Explain why the invention of electron microscopes was important for the development of cell biology.

6. In your own words, describe the contribution Lynn Margulis made to cell biology.

Lynn Margulis (1938 – 2011)

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