Authors: Pallavi Subhraveti Peter D Karp Ingrid Keseler An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Anamika Kothari Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000526375Cyc: Aminiphilus circumscriptus DSM 16581 Cellular Overview Connections between pathways are omitted for legibility. Ron Caspi an amino an amino acid acid phosphate choline an amino an amino glycine betaine acid acid phosphate phosphate phosphate pro dCTP predicted predicted predicted ABC ABC ABC RS0108930 RS0102585 RS0100465 RS0101275 transporter transporter RS0100860 transporter RS0110770 RS0100925 of an of an of phosphate amino acid amino acid choline dCTP glycine betaine an amino an amino phosphate phosphate phosphate pro acid acid an amino an amino phosphate acid acid

Polyprenyl Biosynthesis Glycolysis Aminoacyl-tRNA Charging glutaminyl-tRNA gln UDP-N-acetyl- an O 4 - undecaprenyl- a [protein]- a [protein]- a DNA methyl a mature UDP-N-acetyl- (4R)-4-hydroxy- N 2 - a [protein]-L- biosynthesis via transamidation α a 5-formiminotetrahydrofolate a lipid II 5 NADH glycolysis I (from glucose 6-phosphate) -D-glucosamine diphospho-N- glu methylthymine peptidoglycan α-D-muramoyl- 2-oxoglutarate glutamate-O L-saccharopine Amine and Polyamine Biosynthesis di-trans,poly-cis L-cysteine L-cysteine phosphotriester (n) succinylglutamate ATP roseoflavin in DNA γ -undecaprenyl acetylmuramoyl- (meso-DAP L-alanyl- -D- -methyl-ester 5'-phosphate glu L-threonine degradation I Amino Acid Degradation γ phosphate biosynthesis L-histidine degradation I L-tryptophan degradation to 2-amino- L-alanyl- -D- containing) glutamyl-meso-2,6- penicillin-binding NAD(+) spermidine biosynthesis III D-glucopyranose 6-phosphate methylated-DNA-- methylated-DNA-- bifunctional succinylglutamate spermidine biosynthesis I (2E,6E)-farnesyl 3-carboxymuconate semialdehyde glutamyl-L-lysyl- glutamate diaminopimeloyl- protein 2: chemotaxis saccharopine diphosphatase: IPP [protein]-cysteine S- [protein]-cysteine S- 4-hydroxy-2- desuccinylase: diphosphate thr UDP-N- D-alanyl-D-alanine formimidoyltransferase: lytic D-alanyl-D-alanine K349_RS0111905 response regulator dehydrogenase: riboflavin K349_RS0115300 glucose-6-phosphate his methyltransferase: methyltransferase: oxoglutarate K349_RS0106410 SAM trp acetylglucosamine- K349_RS0114395 transglycosylase protein-glutamate K349_RS0104050 biosynthesis arg SAM isomerase: threonine/serine histidine K349_RS0105500 K349_RS0103760 aldolase/2- succinylglutamate protein RibF: gln an L-glutamyl- di-trans,poly-cis- -N-acetylmuramyl- glutamate domain-containing penicillin-binding a N- methylesterase: [+ 2 isozymes] β K349_RS0115725 dehydratase: ammonia-lyase: methylated-DNA-- dehydro-3-deoxy- desuccinylase: K349_RS0114840 reduced - Gln methylated-DNA-- protein 2: K349_RS0111335 [tRNA ] adenosylmethionine decaprenylcistransferase: glucose-6-phosphate K349_RS0101695 (pentapeptide) formimidoyltransferase: protein: D-ala acetylglucosamine- phosphogluconate K349_RS0106755 nicotinamide D- Asp-tRNA(Asn) adenosylmethionine K349_RS0114390 N-Formyl-L- [protein]-cysteine S- [protein]-cysteine S- K349_RS0111905 AMP decarboxylase: K349_RS0114265 isomerase: threonine/serine pyrophosphoryl- K349_RS0104460 K349_RS0108295 -N-acetylmuramyl- aldolase: chemotaxis-specific ribonucleotide /Glu-tRNA(Gln) Asp-tRNA(Asn) decarboxylase: histidine kynurenine methyltransferase: methyltransferase: allysine roseoflavin K349_RS0115575 K349_RS0113885 dehydratase: L-arginine degradation V undecaprenol N- [+ 3 isozymes] (tetrapeptide) K349_RS0103185 protein-glutamate glu amidotransferase: /Glu-tRNA(Gln) K349_RS0115575 di-trans,octa-cis ammonia-lyase: K349_RS0103760 K349_RS0105500 adenine K349_RS0103265 (arginine deiminase pathway) acetylglucosamine UDP-N- pyrophosphoryl- succinate methyltransferase K349_RS0107620 amidotransferase: dAdoMet agmatine -undecaprenyl (2Z)-2-aminobut- K349_RS0104420 N-formimino- glu dinucleotide putrescine dAdoMet F6P transferase: a tetrahydrofolate a mature GlcNAc-1,6- D-ala acetylmuramoyl- undecaprenol CheB: gatA K349_RS0107620 diphosphate 2-enoate urocanate L-glutamate arg ditrans,octacisK349_RS0114665- UDP a thymine in DNA a [protein]-S- [DNA] a [protein]-S- peptidoglycan anhMurNAc- L-alanyl-γ-D- glyoxylate pyruvate K349_RS0100785 gatA undecaprenyl- (n) K349_RS0107630 polyamine urocanate L-kynurenine undecaprenyldiphospho- methyl-L-cysteine methyl-L-cysteine (meso-DAP L-Ala-γ-D-Glu- glutamyl-meso-2,6- K349_RS0107630 polyamine diphosphate 6-phosphofructokinase: [+ 8 isozymes] aminopropyltransferase: class II fructose- hydratase: N-acetyl-(N-acetyl-β-D- containing) DAP-D-Ala diaminopimeloyl- a 5-phosphooxy- aminopropyltransferase: phosphatase: K349_RS0109655 arginine deiminase: a [protein]-α- K349_RS0114290 bisphosphatase: K349_RS0102435 glucosaminyl)muramoyl- D-alanine MeOH ammonium L-glutamyl- K349_RS0114290 K349_RS0110775 6-phosphofructokinase: 2-iminobutanoate K349_RS0114295 L-glutamate Gln γ [tRNA ] di-trans,octa-cis K349_RS0114495 urocanate L-alanyl- -D-glutamyl-L- 1 K349_RS0111640 N -(3-aminopropyl) -undecaprenyl hydratase: L-methionine degradation lysyl-D-alanyl-D-alanine 3-hydroxy- L-citrulline Asp-tRNA(Asn) agmatine spermidine phosphate K349_RS0104440 I (to L-homocysteine) β L-kynurenine /Glu-tRNA(Gln) DHAP -D-fructose 1,6-bisphosphate 6 met RS0105855 met 4-imidazolone- UDP-N-acetyl- undecaprenyldiphospho- an O - UDP-N-acetylmuramoyl- UDP-N-acetyl- L-alanyl-γ-D- UDP-N-acetyl- a [peptide] amidotransferase: a single a [protein]- a ribonucleoside 2-oxobutanoate 5-propanoate kynureninase: ornithine met α-D-glucosamine N-acetylmuramoyl-L- methylguanine L-alanyl-γ-D- KDGP α-D-muramoyl- D-glt formate glutamyl-meso-2,6- α-D-glucosamine with N-terminal ala UDP-N-acetyl- K349_RS0107620 class I fructose- stranded DNA L-cysteine triphosphate AMP GTP triose-phosphate imidazolonepropionase: K349_RS0105820 carbamoyltransferase: methionine alanyl-γ-D-glutamyl-meso in DNA glutamyl-meso-2,6- L-alanine diaminopimeloyl- UDP-N- β aspartate α-D-muramate gatA spermidine bisphosphate aldolase: 5'/3'-nucleotidase anaerobic isomerase: K349_RS0114400 K349_RS0114300 adenosyltransferase: -2,6-diaminopimeloyl- diaminopimeloyl- D-alanine acetylglucosamine ala RS0107745 ala K349_RS0107630 K349_RS0109925 3-hydroxyanthranilate exodeoxyribonuclease 2-epimerase (non- SurE: ribonucleoside- K349_RS0114575 imidazolonepropionase: K349_RS0112260 D-alanyl-D-alanine methylated-DNA-- D-alanine bifunctional anaerobic beta-aspartyl- VII small subunit: UDP-N- hydrolyzing): K349_RS0112645 UDP-N- triphosphate K349_RS0104450 carbamoyl SAM [protein]-cysteine S- 4-hydroxy-2- ribonucleoside- LD- peptidase: propanoyl-CoA L-ornithine K349_RS0112710 acetylmuramoyl- K349_RS0114240 acetylmuramate-- reductase: an L-glutaminyl- phosphate UDP-N- methyltransferase: LD- oxoglutarate L-alanine--D- triphosphate carboxypeptidase: bifunctional K349_RS0107780 L-alanine ligase: Gln N-formimino- exodeoxyribonuclease K349_RS0108060 biotin RS0103450 biotin [tRNA ] D-glyceraldehyde 3-phosphate phosphate acetylglucosamine- K349_RS0105500 carboxypeptidase: aldolase/2- reductase: K349_RS0110325 UDP-N- metallophosphatase/ L-glutamate 2-amino-3- carbamate kinase: VII large subunit: glutamate ligase: [+ 2 isozymes] K349_RS0114660 propanoyltransferase: -N-acetylmuramyl- methylated-DNA-- K349_RS0110325 dehydro-3-deoxy- K349_RS0108060 acetylglucosamine 5'-nucleotidase: dGTP carboxymuconate- K349_RS0115520 K349_RS0115240 K349_RS0114675 K349_RS0102245 (pentapeptide) [protein]-cysteine S- phosphogluconate γ 2-epimerase (non- K349_RS0102450 tRNA charging glyceraldehyde-3- formimidoylglutamase: [+ 2 isozymes] L-alanyl- -D- UDP-N-acetyl- 6-semialdehyde pyrophosphoryl- 2+ 2+ asp asp phosphate dehydrogenase: K349_RS0102430 SAH methyltransferase: UDP-N-acetyl-α-D- aldolase: a 2'- D-ala glutamyl-meso- hydrolyzing): adenosine α Co RS0102390 Co propanoyl undecaprenol N- UDP-N-acetyl- asp a peptide -D-muramoyl- K349_RS0114585 carbamate a ribonucleoside a single-stranded K349_RS0103760 muramoyl-L-alanyl- K349_RS0103185 α deoxyribonucleoside diaminopimelate K349_RS0106950 RS0105190 phosphate acetylglucosamine D-ala -D-muramoyl-L- UDP-N-acetyl-α- L-alanine phe a tRNA Phe gln a tRNA Gln glu adenosylhomocysteinase: 5'-monophosphate oligodeoxyribonucleotide γ-D-glutamyl-meso- 5'-triphosphate ala ala elongator transferase: alanyl-D-glutamate D-mannosamine Gly Tyr Asn Arg asp His Met Thr Trp glu Ile Cys Ala acetate kinase: L-tryptophan K349_RS0115215 a [protein]-S- 2+ 2+ gly a tRNA tyr a tRNA asn tRNA arg a tRNA tRNA asp his a tRNA Met met initiator tRNA met thr a tRNA trp a tRNA glu a tRNA ile a tRNA cys a tRNA a tRNA ala 2,6-diaminopimelate D-glyceraldehyde Zn RS0101785 Zn tRNA 13-DPG K349_RS0113655 L-serine degradation K349_RS0114665 a guanine in DNA pyruvate lys a tRNA Lys pro a tRNA Pro leu a tRNA Leu val a tRNA Val ser a tRNA ser degradation I methyl-L-cysteine 3-phosphate phenylalanine- glutamine--tRNA (via anthranilate) CO L-homocysteine propanoate 2 lipid II (meso UDP -tRNA ligase: glycine--tRNA ligase: ligase/YqeY domain tyrosine-- asparagine-- arginine-- aspartate-- histidine-- methionine-- methionine-- threonine-- tryptophan-- glutamate-- isoleucine-- cysteine-- alanine-- phosphoglycerate ser K349_RS0115430 K349_RS0114005 fusion protein: tRNA ligase: tRNA ligase: lysine--tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: proline--tRNA ligase: tRNA ligase: tRNA ligase: leucine--tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: valine--tRNA ligase: tRNA ligase: serine--tRNA ligase: tRNA ligase: tRNA ligase: trp diaminopimelate containing) Zn 2+ RS0103695 Zn 2+ kinase: K349_RS0114580 L-threonine threonine/serine glycine degradation K349_RS0115435 K349_RS0114010 K349_RS0101810 K349_RS0107175 K349_RS0107495 K349_RS0107640 K349_RS0107995 K349_RS0108350 K349_RS0108355 K349_RS0109560 K349_RS0111960 K349_RS0111960 K349_RS0112525 K349_RS0113265 K349_RS0113545 K349_RS0114135 K349_RS0114195 K349_RS0114820 K349_RS0114980 K349_RS0115010 K349_RS0115200 degradation II dehydratase: (Stickland reaction) an inactive a carboxy- DNA with adenine:7,8- an N-terminal- K349_RS0101695 + phosphoenol (S)-1-pyrroline- an L-asparaginyl- an L-methionyl- N-Formyl-L- a reduced diphosphate H O menadione NADH H dihydro-8- MoO - L-methionyl-L- an L-phenylalanyl- an L-glutaminyl- an L-tyrosyl- an L-asparaginyl- an L-lysyl- an L-arginyl- an L-aspartyl- an L-histidyl- an L-prolyl- an L-methionyl- an L-leucyl- an L-threonyl- an L-tryptophanyl- an L-glutamyl- an L-valyl- an L-isoleucyl- an L-seryl- an L-cysteinyl- an L-alanyl- 3-phospho-(R)-glycerate L-asparagine ribonucleoside SAM DL-allothreonine 2 adenylated- cys pyruvate 2 5-carboxylate Asn Gly 2-aminoprop-[+ 2 isozymes] L-glutamine kynurenine gly flavodoxin dGDP ATP [tRNA ] IMP ATP sulfite RS0110080 sulfite Phe a glycyl-[tRNA ] Gln Tyr Asn Lys Arg asp His Pro [elongator Met Leu Thr Trp Glu Val Ile ser Cys Ala thr oxoguanine mismatch molybdopterin alanyl-[protein] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [initiator tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] [tRNA ] degradation I degradation I triphosphate [ThiS sulfur- L-glutamate gamma- tRNA Met ] threonine 2-enoate glycine reductase: reductase carrier protein] cofactor semialdehyde 5'/3'-nucleotidase anaerobic 2,3-diphosphoglycerate- dehydrogenase: K349_RS0107750 RdgB/HAM1 family NADH-quinone dehydrogenase: SurE: ribonucleoside- dependent asn serine A/G-specific aminoacyl-tRNA type I methionyl K349_RS0106475 gln [+ 2 isozymes] non-canonical purine oxidoreductase molybdenum cofactor K349_RS0103350 K349_RS0112645 triphosphate sulfite RS0100260 sulfite phosphoglycerate asparaginase: L-2-amino-3- acetyl phosphate anaerobic hydroxymethyltransferase: cysteine pyruvate kinase: adenine hydrolase: aminopeptidase: Asp-tRNA(Asn) L-kynurenine NTP pyrophosphatase: subunit NuoE: guanylyltransferase: bifunctional reductase: mutase: gpmA K349_RS16820 oxobutanoate ribonucleoside- K349_RS0108145 desulfurase NifS: K349_RS0113855 glycosylase: L-glutamate gamma- K349_RS0113940 K349_RS0112140 2-iminopropanoate /Glu-tRNA(Gln) K349_RS0109480 K349_RS0115745 K349_RS0108630 metallophosphatase/ K349_RS0108060 Metabolic Regulator glycine C- triphosphate serine K349_RS0111070 K349_RS0109870 semialdehyde asparaginase: amidotransferase: acetate kinase: NADH-quinone 5'-nucleotidase: dATP Biosynthesis acetyltransferase: kynureninase: reductase hydroxymethyltransferase: glyA sodium-translocating dehydrogenase: a metal a metal 2-phospho-D-glycerate K349_RS0114130 K349_RS0107620 K349_RS0113655 oxidoreductase: an N-terminal L- K349_RS0102450 RS0102620 asp K349_RS0106480 K349_RS0105820 activating protein: pyrophosphatase: adenylyl K349_RS0106300 asn tRNA Asn met cation cation ppGpp metabolism gatA a thiocarboxy- K349_RS0108665 pyruvate an apurinic site alanyl-[protein] acetate K349_RS0108055 K349_RS0111810 ala dGTP molybdenum inosine phosphopyruvate K349_RS0107630 anthranilate AMP [ThiS-Protein] K349_RS0108705 adenine within DNA cofactor glu gly pyruvate acetaldehyde hydratase: [+ 8 isozymes] gly a metal a metal pppGpp an active RS0103880 glu + K349_RS0111830 L-alanine 5'-deoxyadenosine a flavodoxin phosphate H cation cation met ribonucleoside NAD + menadiol Cell Structure Biosynthesis peptidoglycan maturation (meso-diaminopimelate containing) bifunctional (p)ppGpp degradation IV semiquinone synthetase/guanosine- triphosphate guanosine 3'- phosphoenolpyruvate reductase lipid II (meso 3',5'-bis(diphosphate) 3'- diphosphate 5'- ala a metal RS0105345 a metal pyrophosphohydrolase: cation cation diaminopimelate containing) triphosphate 3'- NADH repair alanine K349_RS0111870 (1S,2R)-1- a 2'- N-acetyl-D- an N-terminal- peptidoglycan diphosphatase: pyruvate kinase: dehydrogenase: a peptidoglycan phosphoenol (indol-3- 34 cob(II)alamin coenzyme A D-threo-isocitrate 4-hydroxy- ethylene glycol glycosyltransferase: K349_RS0111870 K349_RS0113855 a 5,10-gly a uridine ATP ser C-(indol-3- deoxyribonucleoside [DNA] dimer (generic) pyruvate yl)pyruvate galactosamine L-methionyl-L- NADH K349_RS0107735 Inorganic Nutrient dADP L-threonine ATP a metal a metal K349_RS0114030 pyruvate methylenetetrahydrofolate in tRNA yl)glycerol 5'-triphosphate 6-phosphate seryl-[protein] biotin propanediol/ RS0114060 Metabolism 3-phosphate glycerol family cation cation a nascent peptidoglycan lytic pyruvate indolepyruvate isocitrate lyase/ dehydratase with (L-alanyl-γ-D- GTP ppGpp urea cycle tRNA uridine-5- cob(I)yrinic acid bifunctional 3'- transglycosylase N-acetylglucosamine- low-specificity L- type I methionyl tryptophan synthase: ferredoxin PEP mutase biotin--[acetyl-CoA- medium: pduC glutamyl-meso-2,6- carboxymethylaminomethyl(34) a,c-diamide 5' exonuclease/ domain-containing pyruvate kinase: 6-phosphate family protein: threonine aldolase: aminopeptidase: K349_RS0103705 oxidoreductase: carboxylase] ligase: pduD pduE + + diaminopimeloyl-D-alanyl- NADHX epimerase: Nucleoside and Nucleotide Degradation synthesis GTPase adenosyltransferase: DNA polymerase: protein: K349_RS0113855 deacetylase: K349_RS0109505 K349_RS0112140 Na RS0111810 Na (R)-NADHX inosine 5'-phosphate superpathway of K349_RS0103710 K349_RS0111100 K349_RS0103025 K349_RS0114425 D-alanine) pentapeptide GDP kinase: K349_RS0112905 degradation guanosine nucleotides arg MnmE: K349_RS0107600 K349_RS0114505 K349_RS0104025 K349_RS0108295 K349_RS0105735 acetaldehyde GDP degradation III pyrimidine ribonucleosides tryptophan synthase [+ 2 isozymes] K349_RS0112135 tRNA uridine-5- [+ 2 isozymes] [+ 3 isozymes] [+ 3 isozymes] an N-terminal penicillin-binding penicillin-binding pyrophosphokinase: bifunctional (p)ppGpp (S)-NADHX degradation ammonium subunit beta: glycolaldehyde carboxymethylaminomethyl(34) pyruvate D-galactosamine glyoxylate succinate gly met L-seryl-[protein] biotinyl-5'- Na + RS0101475 Na + protein 2: protein 2: K349_RS0111870 synthetase/guanosine- IMP cytidine argininosuccinate K349_RS0100705 (indol-3 yl) acetate NAD(P)H-hydrate synthesis enzyme adenosylcobalamin GlcNAc-1,6- dATP 6-phosphate adenylate K349_RS0111905 K349_RS0111905 a mature peptidoglycan with 3',5'-bis(diphosphate) 3'- GMP cytidine deaminase: lyase: glutamine- [DNA] acetyl-CoA dehydratase: IMP dehydrogenase: MnmG: K349_RS0102835 triphosphate anhydro-MurNAc- a lipid II (L-alanyl-γ-D-glutamyl-meso- pyrophosphohydrolase: 5'/3'-nucleotidase K349_RS0107245 K349_RS0112650 hydrolyzing D-glyceraldehyde K349_RS0112905 K349_RS0114890 trp pentapeptide a nascent peptidoglycan a nascent peptidoglycan 2,6-diaminopimeloyl-D-alanyl- K349_RS0111870 SurE: [+ 3 isozymes] carbamoyl- 3-phosphate Na + RS0112675 Na + with (L-alanyl-γ-D-glutamyl- with D,D cross-links (meso- K349_RS0112645 uridine L-arginino- phosphate synthase: 34 D-alanine) pentapeptide GDP NADH XMP L-ornithine a 5-carboxymethylaminomethyluridine a 7,8-dihydrofolate meso-2,6-diaminopimeloyl- diaminopimelate containing) bifunctional pyrimidine/purine succinate K349_RS0101760 in tRNA D-alanine) tetrapeptide 5'/3'-nucleotidase metallophosphatase/ nucleoside K349_RS0101765 Na + RS0107795 Na + SurE: 5'-nucleotidase: phosphorylase: carbamoyl a 2'- 3-benzyl-3,6 - a peptidoglycan an N-terminal- a peptide with L,D- LD- L,D- a 2-oxo a (6S)-5- an L-cysteinyl- a mature peptidoglycan K349_RS0112645 K349_RS0102450 K349_RS0101215 ornithine phosphate 2-oxoglutarate deoxyribonucleoside bis(cysteinylglycine) dimer (E. faeciums) (S)-mandelate L-methionyl-L- a reduced formate an N-terminal transpeptidase: carboxypeptidase: transpeptidase: carboxylate glu formyltetrahydrofolate [DNA] CTP Cys a protein with D,D cross-links (meso- bifunctional guanosine argininosuccinate rubredoxin superoxide [tRNA ] K349_RS17820 K349_RS0110325 K349_RS17820 Respiration uracil carbamoyltransferase: 5'-triphosphate - 6-(hydroxymethyl) mandelate racemase/ threonyl-[protein] L-methionine a mature peptidoglycan diaminopimelate containing) metallophosphatase/ synthase: ATP-dependent predicted γ K349_RS0114300 -diketopiperazine penicillin-binding muconate lactonizing with (L-alanyl- -D-glutamyl- 5'-nucleotidase: pyrimidine/purine K349_RS0113070 2-oxoglutarate 2-oxoacid anaerobic protease ABC a nascent peptidoglycan a nascent peptidoglycan a nascent peptidoglycan glutamate bifunctional 3'- protein 2: enzyme family protein: type I methionyl aminoacyl-tRNA type I methionyl a sugar a sugar meso-2,6-diaminopimeloyl- 2-oxoisovalerate decarboxylation to isobutanoyl-CoA K349_RS0102450 nucleoside L-citrulline oxidoreductase: ferredoxin Neelaredoxin: ribonucleoside- subunit HslV: transporter with L,D cross links (meso- with (L-alanyl-γ-D- with (L-alanyl-γ-D-glutamyl- formimidoyltransferase: 5' exonuclease/ membrane K349_RS0111905 K349_RS0101405 aminopeptidase: hydrolase: aminopeptidase: D-alanine) tetrapeptide phosphorylase: K349_RS0115120 oxidoreductase: K349_RS0102685 triphosphate K349_RS0111170 of a sugar diaminopimelate containing) glutamyl-meso-2,6- meso-2,6-diaminopimeloyl- an [apo BCAA K349_RS0114395 DNA polymerase: dipeptidase: mandelate racemase/ K349_RS0112140 K349_RS0113940 K349_RS0112140 K349_RS0101215 5,6-dihydrouracil purine ribonucleosides degradation K349_RS0111000 reductase: a peptide diaminopimelate) tripeptide glycine) tetrapeptide dehydrogenase xanthosine 2-oxoglutarate K349_RS0104025 K349_RS0104675 muconate lactonizing purine-nucleoside glutamate a peptidoglycan K349_RS0108060 a sugar RS0103970 a sugar Cofactor, Carrier, and Vitamin Biosynthesis E2 protein] N 6 3-methyl-2- hydantoinase/ ferredoxin [+ 2 isozymes] enzyme family protein: phosphorylase: formimidoyltransferase: [+ 3 isozymes] tetramer with a D-ala an N-terminal L- an oxidized -lipoyl-L-lysine oxobutanoate oxoprolinase oxidoreductase Cys a mature peptidoglycan pyrimidine/purine K349_RS0104460 3-benzyl-3,6 - D,D cross-link K349_RS0101410 met threonyl-[protein] cys a tRNA met a peptide 3-methyl-2- dehydrogenase K349_RS0115100 family protein: adenosine subunit gamma: a reduced rubredoxin dCTP with L,D cross-links (meso- a mature peptidoglycan a mature peptidoglycan cob(II)yrinate a,c- nucleoside + bis(cysteinyl)- 6- (R)-mandelate [2Fe-2S] iron-sulfur pyridoxal 5'-phosphate biosynthesis I thiamine diphosphate 4-amino-2-methyl-5- subunit VorB: K349_RS0112980 an acyl-CoA CO H gly (Enterococcus diaminopimelate containing) with (L-alanyl-γ-D- with (L-alanyl-γ-D-glutamyl- diamide biosynthesis I 6-hydroxymethyl-dihydropterin coenzyme A biosynthesis I (prokaryotic) oxobutanoate phosphorylase: K349_RS0105220 2 ferredoxin [iron- [DNA] (hydroxymethyl) a sugar RS0105030 a sugar cluster biosynthesis flavin biosynthesis I (bacteria and plants) biosynthesis III diphosphomethylpyrimidine K349_RS0115125 guanine adenosine faecium) glutamyl-meso-2,6- meso-2,6-diaminopimeloyl- (early cobalt insertion) diphosphate biosynthesis I dehydrogenase K349_RS0101215 [+ 2 isozymes] sulfur] cluster N-formyl- a tetrahydrofolate -diketopiperazine D-erythrose (R)-4'- (Staphylococcus) biosynthesis I deaminase: diaminopimelate) tripeptide glycine) tetrapeptide 2-(2-carboxy-4- subunit VorB: purine-nucleoside a reduced L-glutamate uroporphyrinogen-III L-cysteine desulfurase 4-phosphate phosphopantothenate 3-ureidopropanoate K349_RS0115205 CO H + succinyl-CoA bifunctional methylthiazol-5- K349_RS0115125an [apo BCAA 2 ferredoxin [iron- uroporphyrinogen-III GTP GTP HMP-PP AIR SAM an [apo BCAA dehydrogenase phosphorylase: a sugar RS0109295 a sugar phosphopantothenoylcysteine yl)ethyl phosphate dehydrogenase K349_RS0115100 sulfur] cluster C-methyltransferase: cysteine GTP cyclohydrolase E2 protein] N 6 -S-[2- xanthosine adenosine inosine guanosine decarboxylase/ E2 protein] N 6 K349_RS0102080 desulfurase NifS: bifunctional I FolE2: methylpropanoyl]dihydrolipoyl- 4-phospho- 7,8- phosphopantothenate--cysteine thiamine phosphate phosphomethylpyrimidine -dihydrolipoyl- xanthine xanthine di-trans,octa-cis an N-terminal- precorrin-1 K349_RS0111070 3,4-dihydroxy- K349_RS0102905 L-lysine UDP-N-acetyl- (S)-methylmalonyl- 2-deoxy-D-ribose β-aspartyl an N-modified D-sedoheptulose D-erythronate ligase CoaBC: K349_RS0113605 synthase: synthase ThiC: L-lysine α pyruvate Ala a cytidine 34 a sugar RS0100560 a sugar 2-butanone- dihydroneopterin (R)-4'- xanthine xanthine β-alanine -undecaprenyl -D-muramoyl- dGTP CoA ATP 5-phosphate dipeptide a glycyl-[tRNA ] lys 1,7-bisphosphate L-methionyl- a protein uroporphyrinogen-III an S-sulfanyl-[L- K349_RS0108810 pyrimidine/purine pyrimidine/purine pyrimidine/purine pyrimidine/purine a tRNA precursor aminoacyl-[tRNA] Ile2 hypoxanthine 4-phosphate 3'-triphosphate phosphopantothenoyl- K349_RS0102750 phosphatephospho-N- L-alanyl-γ-D- in tRNA glycyl-[protein] C-methyltransferase: cysteine desulfurase] dehydrogenase: dehydrogenase: nucleoside nucleoside nucleoside nucleoside CTP synthase/GTP L-cysteine acetylmuramoyl- glutamyl-meso-2,6- xanthine endopeptidase La: K349_RS0102080 K349_RS0102505 K349_RS0102505 phosphorylase: phosphorylase: phosphorylase: phosphorylase: methylmalonyl-CoA deoxyribose- beta-aspartyl- class I fructose- formate formate scaffold protein cyclohydrolase II: bifunctional thiamine 3-methyl-2- pentapeptide- diaminopimeloyl- aminoacyl-tRNA D-tyrosyl-tRNA(Tyr) tRNA lysidine(34) type I methionyl dehydrogenase: K349_RS0114185 RS0108635 (3R)-3-hydroxy-2-oxo- HMP-P xanthine xanthine K349_RS0101215 K349_RS0101215 K349_RS0101215 K349_RS0101215 carboxyltransferase: phosphate aldolase: peptidase: bisphosphate nitrite nitrite Secondary Metabolite Biosynthesis precorrin-2 for iron-sulfur K349_RS0114990 4 phosphooxybutanoate 7,8- phosphopantothenoylcysteine phosphate oxobutanoate transferase: D-alanyl-D-alanine deoxyguanosinetriphosphate CCA tRNA hydrolase: deacylase: synthetase TilS: aminopeptidase: K349_RS0102505 2,5-diamino-6- dehydrogenase: dehydrogenase: purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside K349_RS0114680 triphosphohydrolase: K349_RS0109735 nucleotidyltransferase: K349_RS0110665 K349_RS0107780 aldolase: cluster assembly: dihydroneopterin decarboxylase/ bifunctional dehydrogenase K349_RS0106250 K349_RS0106250 K349_RS0113940 K349_RS0111875 K349_RS18200 K349_RS0109925 K349_RS0112140 xanthine a peptide K349_RS0111075 (5-phospho-D- 3'-phosphate phosphopantothenate--cysteine hydroxymethylpyrimidine subunit VorB: phosphorylase: phosphorylase: phosphorylase: phosphorylase: K349_RS0114025 methylmalonyl-CoA K349_RS0104230 deoxyribose- [+ 2 isozymes] dehydrogenase: methylerythritol phosphate pathway I + + preQ biosynthesis an S-sulfanyl-[cysteine ribosylamino) ligase CoaBC: K349_RS0113605 kinase/ K349_RS0115125 urate urate K349_RS0115100 K349_RS0115100 K349_RS0115100 K349_RS0115100 carboxyltransferase: phosphate aldolase: K349_RS0106250 H RS17630 H 0 D-glyceraldehyde K349_RS0109760 K349_RS0109525 an uncharged a lysidine 34 an N-terminal desulfurase]-[disordered- pyrimidin- 4-phosphooxy- pyruvate phosphomethylpyrimidine a tRNA an N-modified Ala D-erythrose xanthine D-glyceraldehyde 3-phosphate thiamine α a proteinogenic a tRNA gly Ile2 DHAP met pyruvate form scaffold 4(3H)-one 4'-phosphopantetheine -D-ribose- asp amino acid tRNA in tRNA 4-phosphate glycyl-[protein] 3-phosphate sirohydrochlorin L-threonine kinase: K349_RS0108800 undecaprenyldiphospho- 2'-deoxyguanosine triphosphate containing a amino acid thiamine RS0109825 thiamine protein] complex bifunctional D-erythro-7,8- thiamine 1-phosphate UMP GTP [cysteine desulfurase]-S- D-ribulose 4-hydroxythreonine- 1-deoxy-D-xylulose- pantetheine- N-acetylmuramoyl-L- 3' CCA end D-glyceraldehyde V-type ATP sirohydrochlorin diaminohydroxyphosphoribosylaminopyrimidine dihydroneopterin diphosphokinase: HMP-PP Macromolecule Modification pyrimidine deoxyribonucleosides degradation oxaloacetate propanoyl-CoA acetaldehyde H + H + GTP cyclohydrolase sulfanylcysteine:[acceptor 5-phosphate 4-phosphate 5-phosphate phosphate UTP and CTP dephosphorylation I alanyl-γ-D-glutamyl-meso 3-phosphate synthase 1-deoxy-D-xylulose- cobaltochelatase: deaminase/5-amino-6-(5-phosphoribosylamino) dihydroneopterin K349_RS0112705 5-phosphate I FolE2: protein]-cysteine dehydrogenase synthase: adenylyltransferase: thymine degradation -2,6-diaminopimeloyl- 7,8- K349_RS0104210 bifunctional uracil reductase RibD: K349_RS0115000 aldolase: tRNA-uridine 2-thiolation 2'-deoxycytidine synthase: K349_RS0102905 sulfurtransferase: PdxA: K349_RS0112720 K349_RS0113645 thiamine adenosylcobalamin D-ribose 5- UTP D-alanyl-D-alanine dihydroneopterin cobalt- 3,4-dihydroxy- 5-amino-6-(5- K349_RS17525 and selenation (bacteria) K349_RS0112720 K349_RS0111070 K349_RS0104170 diphosphate biosynthesis from thymine phosphate V-type ATP sirohydrochlorin 2-butanone- phospho-D- 3'-dephospho- cytidine deaminase: H + H + 3'-triphosphate a [cysteine desulfurase]- 3-amino-1- 1-deoxy-D- 6-(hydroxymethyl) adenosylcobinamide-GDP I CTP synthase: synthase 4-phosphate ribosylamino)uracil CoA K349_RS0107245 34 an N-terminal- an N-terminal- 1-deoxy-D-xylulose 6-carboxytetrahydropterin S-sulfanyl-[disordered- hydroxyacetone xylulose 5- -7,8-dihydropterin cys K349_RS0111680 a 5,10- a 2-thiouridine L-threo-3- a D-aspartyl- an L-aspartyl- D-sedoheptulose synthase/GTP bifunctional dephospho- 5,6-dimethylbenzimidazole 5,6-dihydrothymine [+ 3 isozymes] thymidine pyruvate (S)-4-hydroxymandelate citrate acetyl-CoA L-methionyl-L- L-methionyl-L- SAICAR L-ornithine 5-phosphate synthase QueD: form scaffold 1-phosphate phosphate 2-amino-4-hydroxy-6- tetrahydrofolate biosynthesis methylenetetrahydrofolate in tRNA ATP phenylserine [tRNA asp ] [tRNA Asn ] 1-phosphate cyclohydrolase II: diaminohydroxyphosphoribosylaminopyrimidine CoA kinase: UDP ammonium hydrogencarbonate mandelate racemase/ cysteinyl-[protein] valyl-[protein] K349_RS0102865 protein] complex hydroxymethyldihydropteridine cysteine hydantoinase/ CTP Asp-tRNA(Asn) V-type ATP 1-deoxy-D-xylulose- K349_RS0114990 deaminase/5-amino-6-(5-phosphoribosylamino) 2'-deoxyuridine pyrimidine/purine ornithine + + 6-carboxy-5,6,7,8- cobalt-factor III cysteine diphosphokinase: K349_RS17215 (7,8-dihydropterin- adeninyl adenosylcobamide desulfurase NifS: muconate lactonizing /Glu-tRNA(Gln) H H 5-phosphate uracil reductase RibD: K349_RS0115000 α-ribazole oxoprolinase nucleoside tRNA uridine-5- pyruvate, citrate lyase class I fructose- adenylosuccinate cyclodeaminase: synthase tetrahydropterin desulfurase NifS: 3,4-dihydroxy- K349_RS0102905 6-yl)methyl biosynthesis from K349_RS0111070 enzyme family protein: low-specificity L- type I methionyl D-tyrosyl-tRNA(Tyr) amidotransferase: type I methionyl reductoisomerase: 5-amino-6-(5- coenzyme A 4-aminobenzoate 5'-phosphate family protein: phosphorylase: carboxymethylaminomethyl(34) phosphate dikinase: subunit alpha: bisphosphate lyase: K349_RS0109015 K349_RS0111070 2-butanone- (7,8-dihydropterin- diphosphate adenosylcobinamide-GDP an [L-cysteine UMP carbamate kinase: K349_RS0101405 threonine aldolase: aminopeptidase: deacylase: K349_RS0107620 aminopeptidase: K349_RS0114275 an S-sulfanyl-[cysteine phospho-D- pyridoxine K349_RS0105220 pyrimidine/purine K349_RS0101215 synthesis GTPase K349_RS0115700 K349_RS0115475 aldolase: K349_RS0114490 4-phosphate 6-yl)methyl adenosylcobinamide- desulfurase]-S- CDP K349_RS0106770 mandelate racemase/ K349_RS0109505 K349_RS0112140 K349_RS0111875 gatA K349_RS0112140 pro desulfurase]-S- ribitylamino)uracil 5'-phosphate dihydropteroate GDP sulfanyl-L-cysteine [+ 2 isozymes] nucleoside thymidine 5'/3'-nucleotidase MnmE: K349_RS0107600 [+ 2 isozymes] citrate lyase K349_RS0109925 synthase: diphosphate adenine phosphorylase: carbamate kinase: muconate lactonizing K349_RS0107630 MEP cobalt-precorrin-3 sulfanyl-[disordered- synthase: ribazoletransferase: phosphorylase: SurE: tRNA uridine-5- subunit alpha: an L-asparaginyl- 7-carboxy-7- K349_RS0105645 3-(carbamoylamino)- K349_RS0101215 K349_RS0115520 enzyme family protein: AICAR fumarate form scaffold K349_RS0115095 K349_RS0112645 K349_RS0108870 an N-terminal L- Asn an N-terminal deazaguanine 1-deoxy-L- K349_RS16210 K349_RS0103255 2-methylpropanoate carboxymethylaminomethyl(34) phosphoenol K349_RS0101410 benzaldehyde asp [tRNA ] 2-C-methyl-D- cobalt-precorrin 3 protein] complex CMP H + gly met cysteinyl-[protein] tRNA D-aspartate DHAP D-erythrose met L-valyl-[protein] [cysteine desulfurase]-S- glycero-tetrulose adenosylcobalamin a [TusA sulfur- bifunctional synthesis enzyme pyruvate diphosphate erythritol 4-phosphate methyltransferase: ARP thymine AMP carbamoyl (R)-4-hydroxymandelate sulfanylcysteine:[acceptor 4-phosphate PLP 7,8- adenine ribotide 5'-phosphate carrier protein]-S- 5'/3'-nucleotidase metallophosphatase/ MnmG: K349_RS0102835 cytidylyltransferase: K349_RS0102050 adenosylcobalamin phosphate (3S)-citryl-CoA acetate protein]-cysteine dihydropteroate phosphate sulfanyl-L-cysteine SurE: 5'-nucleotidase: K349_RS0114895 salvage from cobalamin thiamine diphosphate salvage II 4-(cytidine 5'- preQ cobalt-precorrin-4 sulfurtransferase: 6,7-dimethyl-8- (R)-3-amino-2- K349_RS0112645 K349_RS0102450 a 5-aminomethyl-2- 0 adenosylcobinamide- a 7,8-dihydrofolate K349_RS0111070 ribityllumazine methylpropanoate thiouridine 34 in tRNA diphospho)-2-C- cobalt precorrin- a [cysteine cob(I)alamin 4-amino-2-methyl-5- GDP bifunctional uridine methyl-D-erythritol desulfurase]-(S- synthase: a [TusD sulfur- metallophosphatase/ 4 (C 11 )- pyrimidinemethanol 7,8-dihydrofolate ribazoletransferase: adenosylcobalamin sulfanyl) -[disordered- K349_RS0114985 molybdenum cofactor biosynthesis carrier protein]-S- 5'-nucleotidase: methyltransferase: 2 bifunctional monoglutamate K349_RS0103255 2-deoxy-α- molybdopterin Coα-[α-(adenin- uracil quinoxaline-2- a double 2+ form scaffold cob(II)alamin sulfanyl-L-cysteine purine deoxyribonucleosides degradation I K349_RS0102450 hydrogen selenide tungstate a nucleoside a D-tryptophanyl- a D-tyrosyl- Co precorrin-2 an L-glutamyl- an L-cysteinyl- K349_RS0102045 hydroxymethylpyrimidine β D-ribose 1- O-acetyl-L-serine aryl-carrier protein adenine a ribonucleic acid Trp Tyr Gln Pro a protein pro protein] complex 6,7-dimethyl-8-(1- 9-yl)]-Co - Detoxification carboxyl adenylate bis(tungstenpterin) GTP triphosphate [tRNA ] [tRNA ] stranded DNA [tRNA ] [tRNA ] 2-phospho-4-(cytidine cobalt- D-ribityl)lumazine GTP kinase/ adenosylcobamide phosphate cytidine dinucleotide DNA gyrase Asp-tRNA(Asn) ATP-dependent 5'-diphospho)-2-C- cob(I)yrinic acid phosphomethylpyrimidine deoxyadenosine cofactor subunit A: precorrin-5A riboflavin synthase: a,c-diamide cys ATP 5'-phosphate sirohydrochlorin /Glu-tRNA(Gln) Clp endopeptidase proline racemase: methyl-D-erythritol kinase: K349_RS0108800 a 7,8-dihydrofolate a [TusE sulfur deaminase: 2'-deoxyadenosine arsenate detoxification I (mammalian) O-acetylhomoserine molybdopterin DNA-directed K349_RS0109845 K349_RS0114995 adenosyltransferase: GTP 3',8- pyrimidine deoxyribonucleotides arsenate acyl carrier protein: D-tyrosyl-tRNA(Tyr) D-tyrosyl-tRNA(Tyr) cobaltochelatase: amidotransferase: Cys-tRNA(Pro) proteolytic K349_RS0112660 2-C-methyl-D- 34 carrier protein]-S K349_RS0115205 aminocarboxypropyltransferase/ molybdotransferase molybdenum cofactor a [cysteine desulfurase]- cysteine cyclase MoaA: a uridine in tRNA dephosphorylation RNA polymerase: deacylase: deacylase: DNA topoisomerase K349_RS0104210 K349_RS0107620 deacylase: subunit ClpP: erythritol 2,4- K349_RS0114505 HMP-P -sulfanylcysteine detoxification cysteine synthase: K349_RS0113700 MoeA: guanylyltransferase: [scaffold protein- riboflavin desulfurase NifS: K349_RS0114615 α α nucleoside triphosphate arsenate K349_RS0111990 K349_RS0111875 K349_RS0111875 (ATP-hydrolyzing) gatA K349_RS0110650 K349_RS0114175 D-proline cyclodiphosphate cobalt- [+ 2 isozymes] 5-(2-hydroxyethyl) Co -[ -(adenin- II (glutaredoxin) K349_RS0100940 K349_RS0114625 K349_RS0108630 (2Fe-2S)] complex K349_RS0111070 (8S)-3',8-cyclo-7,8- bifunctional β pyrophosphohydrolase: 2'-deoxyinosine 2'-deoxyguanosine K349_RS0111995 subunit B: K349_RS0107630 synthase: precorrin-5B cob(II)alamin- an [L-cysteine a carboxy-adenylated -4-methylthiazole 7-yl)]-Co - tRNA 2- arsenate an L-glutaminyl- a peptide riboflavin [corrinoid dihydroguanosine hydroxymethylpyrimidine adenosylcobamide K349_RS0113955 cysteine synthase a quinoxaline-2- [+ 2 isozymes] K349_RS0103600 cobalt-precorrin-2 K349_RS0114895 desulfurase]-S- [small subunit of hydroxyethylthiazole a tetrahydrofolate thiouridine(34) dCTP dCMP pyrimidine/purine pyrimidine/purine arsenate arsenate WO - a negatively [tRNA Gln ] biosynthesis 5'-triphosphate kinase/ A: K349_RS0107605 carboxyl-[aryl- 2 bis(guanylyl D-tryptophan a tRNA Trp D-tyrosine a tRNA Tyr cys a tRNA Pro adenosyltranferase] kinase: synthase MnmA: nucleoside nucleoside reductase ArsC: AMP molybdopterin supercoiled DNA 2-C-methyl-D-erythritol- protein RibF: sulfanyl-L-cysteine molybdopterin synthase] cyclic pyranopterin phosphomethylpyrimidine pyrimidine/purine pyrimidine/purine reductase ArsC: carrier protein] AMP tungstenpterin) cofactor a [co-chaperone]- K349_RS0108805 K349_RS0114510 phosphorylase: phosphorylase: K349_RS0102705 cofactor 2,4-cyclodiphosphate K349_RS0114840 monophosphate kinase: K349_RS0108800 dUTP diphosphatase: nucleoside nucleoside K349_RS0102705 a ribonucleic acid cobalt- [scaffold protein- 4-methyl-5-(2- K349_RS0101215 K349_RS0101215 arsenite acetate (2Fe-2S)] complex synthase MoaC: K349_RS17220 phosphorylase: phosphorylase: L-selenocysteine flavodoxin- precorrin-6A FMN phosphooxyethyl) NAD salvage pathway I (PNC VI cycle) a 2-thiouridine 34 cob(I)alamin- K349_RS0114610 HMP-PP K349_RS0101215 purine-nucleoside K349_RS0101215 purine-nucleoside arsenite dependent (E)-4- precorrin-6A/ [corrinoid a thiocarboxylated thiazole in tRNA nucleoside triphosphate phosphorylase: phosphorylase: hydroxy-3-methylbut- riboflavin cyclic pyranopterin pyrophosphohydrolase: purine-nucleoside purine-nucleoside cobalt-precorrin- adenosyltranferase] [small subunit of phosphopantothenate biosynthesis I NAD + tRNA uridine-5- K349_RS0115100 K349_RS0115100 2-enyl-diphosphate 6A reductase: a [chaperone-ATP]- biosynthesis cob(I)yrinic acid phosphate thiamine phosphate K349_RS0113955 phosphorylase: phosphorylase: a mature peptidoglycan (meso an [HPr]- phosphoenol DNA combined a ribonucleoside a guanine 46 L-fuculose (3R,5S)-3- molybdopterin synthase] carboxymethylaminomethyl(34) dUTP dUMP an acyl-[acyl-carrier protein] an unsulfurated cys L-allo-threonine asp O-ureido-L- formate butanoate synthase: K349_RS0102055 [co-chaperone]- protein RibF: a,c-diamide synthase: NAD+ synthetase, K349_RS0115100 K349_RS0115100 arsenite -diaminopimelate containing) L-histidine pyruvate with exogenous 5'-monophosphate in tRNA 1-phosphate UTP hydroxy-1- 3-methyl-2-oxobutanoate NAD(+) synthesis GTPase [sulfur carrier] homoserine tRNA butyrate kinase: K349_RS0114285 [scaffold protein- K349_RS0114840 adenosyltransferase: K349_RS0108810 glutamine ribose-1-arsenate arsenic DNA to form a bifunctional pyrroline-5- cobalt- diphosphatase: MnmE: K349_RS0107600 α (guanosine(46)-N7) K349_RS0108970 (E)-4-hydroxy-3- (2Fe-2S)] complex K349_RS0114505 dependent: 2-deoxy- -D- triglutathione lytic transglycosylase recombinationalHolliday junction metallophosphatase/ carboxylatepyrroline-5- precorrin-6B FAD 3-methyl-2-oxobutanoate NAD(+) synthase: K349_RS0115300 tRNA uridine-5- 5-hydroxy-CTP 5-hydroxy-CMP phosphoenolpyruvate- -methyltransferase L-fuculose- anaerobic methylbut-2-en- thiamine K349_RS0114335 ribose 1-phosphate arsenite domain-containing phosphate cysteine junction resolvase RuvX: low-specificity L- 5'-nucleotidase: argininosuccinate carboxylate butyrate kinase: [+ 2 isozymes] citrate lyase hydroxymethyltransferase: K349_RS0114335 carboxymethylaminomethyl(34) -protein TrmB: phosphate aldolase: ribonucleoside- 1-yl diphosphate adenosylcob(III) molybdopterin phosphate methyltransferase: protein: acyltransferase PlsX: desulfurase NifS: K349_RS0115195 threonine aldolase: K349_RS0102450 synthase: reductase: K349_RS0108985 activation K349_RS0104000 nicotinate adenine NMN synthesis enzyme phosphotransferase: K349_RS0113635 K349_RS0111020 triphosphate butanoyl alamin-[corrinoid K349_RS0101670 K349_RS0108295 K349_RS0113675 K349_RS0111070 K349_RS0109505 K349_RS0113070 an N 7 - K349_RS0105350 4-hydroxy-3- molybdopterin dinucleotide MnmG: K349_RS0102835 K349_RS0108780 crossover junction 5'/3'-nucleotidase reductase: phosphate 3'-dephospho- 2-dehydropantoate 46 Hyp a [chaperone- adenosyltranferase] adenylyltransferase: [+ 3 isozymes] resolution ofendodeoxyribonuclease SurE: methylguanine K349_RS0108060 methylbut-2-enyl cobalt-precorrin-7 an [2Fe-2S] CoA nicotinate-nucleotide a 5-carboxymethylaminomethyl- dimethylarsonite ADP]-[disordered- 2-methyladeninyl cob(I)yrinic acid K349_RS17395 an [HPr protein]- recombinationalRuvC: K349_RS0114345 K349_RS0112645 in tRNA DHAP (S)-lactaldehyde diphosphate cluster protein 2-dehydropantoate 2- adenylyltransferase: 2-thiouridine 34 in tRNA a sulfurated acetaldehyde canavaninosuccinate 4-hydroxy-3- form scaffold adenosylcobamide biosynthesis a,c-diamide thiamine a mature peptidoglycan a mature peptidoglycan strand N π -phospho- pyruvate acyl-carrier protein an acyl phosphate ala junction gly a ribonucleoside reductase: protein] complex molybdopterin reductase: K349_RS17280 K349_RS0114560 [sulfur carrier] dUTP methylbut-2-enyl K349_RS0115155 from adenosylcobinamide-GDP adenosyltransferase: adenine dinucleotide diphosphate with (L-alanyl-γ-D-glutamyl- (non-reducing terminus) L-histidine formation of two β Carboxylate Degradation diphosphate 2-methyladenine K349_RS0114505 2'-(5''-triphospho- -alanine (R)-pantoate meso-2,6-diaminopimeloyl- intact strands α molybdopterin NaMN nicotinamide reductase: cobalt-precorrin-8 [+ 2 isozymes] -D-ribosyl)-3'- a 5-aminomethyl-2- Fatty Acid and Lipid Degradation cacodylate D-alanine) tetrapeptide IPP molybdotransferase K349_RS0115155 an [Fe-S cluster dephospho-CoA 34 pyruvate fermentation adenosylcobalamin MoeA: thiouridine in tRNA biosynthesis 5-methylbenzimidazolyl NAD salvage pantoate--beta-alanine β to acetate IV L-alanyl-γ-D- K349_RS0114625 oleate -oxidation a nascent peptidoglycan a [DNA]-3'- a 5'-phospho- N-acetyl-muramoyl-(L- a 1-acyl-2- (S)-4-hydroxy- an apo-[FeFe] a guanine 37 a (1->4)- chaperone]-ATP 2-methyladenine ligase: K349_RS0113250 nicotinate androstenedione degradation NAD + a [ThiI sulfur-carrier γ DNA with lesion citrate α MoO -molybdopterin adenosylcobamide biosynthesis pathway III (to citrate degradation (meso-DAP containing) hydroxyl [DNA] cys alanyl- -D-glutamyl-L- arachidonoyl- glutamyl-L-lysyl- 2-oxopentanoate hydrogenase in tRNA -D-glucan ser ribotide phosphate 2 phosphoribosyltransferase: pyruvate protein]-L-cysteine 1,4-alpha-glucan cobyrinate a holo [citrate cofactor from adenosylcobinamide-GDP nicotinamide riboside) thiamine diphosphate lysyl-D-alanyl-D-alanine) sn-glycerol D-alanyl-D-alanine subunit [FeFe] tRNA excinuclease ABC: K349_RS0109470 a 5-methylaminomethyl- oleate branching threonine/serine lyase acyl- + (R)-pantothenate androst-4-ene-3,17-dione an acetyl-holo 3-phosphate CTP (guanosine(37)-N1) K349_RS0112860 adenosylcobinamide- 5-methylbenzimidazole NADP nicotinate biosynthesis I (E. coli) 34 lytic transglycosylase NAD-dependent hydrogenase H- dehydratase: cobyrinate A,C- 2-thiouridine in tRNA [citrate lyase acyl- 4-hydroxy-2- -methyltransferase K349_RS0112865 citrate lyase protein GlgB: DMAPP GDP carrier protein] 2-[(2R,5Z)- citrate domain-containing DNA ligase LigA: cysteine penicillin-binding penicillin-binding cluster radical SAM K349_RS0101695 diamide synthase: type III pantothenate carrier protein] oxovalerate TrmD: subunit alpha: K349_RS0107270 ribazoletransferase: [citrate (pro-3S) 2-carboxy-4- protein: K349_RS0107635 desulfurase NifS: protein 2: phosphatidate protein 2: maturase HydG: excinuclease ABC a (1,6)-α-D- K349_RS0102130 kinase: K349_RS0107650 aldolase: K349_RS0108220 K349_RS0108870 [+ 2 isozymes] K349_RS0103255 -lyase] ligase: 5-methylbenzimidazole + K349_RS0111070 K349_RS0111905 cytidylyltransferase: K349_RS0111905 K349_RS0106360 1 subunit UvrC: Coα-[α-(2- NAD methylthiazol-5(2H acetyl-CoA formate citrate lyase acyl K349_RS0108295 K349_RS0103195 an N - [+ 4 isozymes] glucosyl-(1,4) pyruvate cob(II)yrinate K349_RS0107475 ribotide phosphate a 5-methylaminomethyl- oleoyl-CoA K349_RS0114270 37 K349_RS0115005 α methyladenin-9-yl)]-Co (R)-4'-phosphopantothenate HMP-PP )-ylidene]ethyl androsta-1,4-diene-3,17-dione carrier protein: [+ 3 isozymes] an active [FeFe][+ 2 isozymes] methylguanine DNA without - -glucan a,c-diamide an acetyl-holo adenosylcobinamide- NAD(+) benzimidazolyl adenosylcobamide phosphate 2-(S-geranyl) [DNA] NMN a [ThiI sulfur- N-acetyl-muramoyl-(L- L-alanyl-γ-D- in tRNA β 34 bifunctional enoyl- K349_RS0108860 hydrogenase -adenosylcobamide [citrate lyase acyl- diphosphatase: biosynthesis from adenosylcobinamide-GDP thiouridine in tRNA AMP γ lesion GDP CoA hydratase/ a mature peptidoglycan a nascent peptidoglycan ala carrier protein]-S- alanyl- -D-glutamyl- D-ala a CDP-1-acyl- glutamyl-L- D-ala acetaldehyde pyruvate subunit acetate oxaloacetate thiamine diphosphate 5'-phosphate carrier protein] K349_RS0115300 [+ 4 isozymes] NAD salvage pathway II (PNC IV cycle) ribazoletransferase: thiamine phosphate phosphate with (L-alanyl-γ-D-glutamyl- (meso-DAP containing) sulfanyl-L-cysteine L-lysyl-D-alanine) 2-arachidonoyl- lysyl-D-alanine biosynthesis II (Bacillus) benzimidazole K349_RS0103255 synthase: (2E,9Z)- acetyltransferase: a citryl-holo meso-2,6-diaminopimeloyl- with GlcNAc terminus glycerol α α NMN 9α-hydroxyandrosta- 2-(2-carboxy-4- Co -[ -(5- bis(guanylyl molybdenum K349_RS0108810 a 5-methylaminomethyl- octadecenoyl-CoA K349_RS0108980 [citrate lyase acyl- D-alanine) tetrapeptide Coα-[α-(2- NAD + 1,4-diene-3,17-dione HMP-PP methylthiazol-5- NAD(+) methylbenzimidazolyl)]- bifunctional cofactor) biosynthesis 2-(Se-phospho) carrier protein] methyladenin-7-yl)]-Co NAD+ synthetase, β benzimidazole 34 yl)ethyl phosphate diphosphatase: tetrahydrofolate salvage from Co -adenosylcobamide metallophosphatase/ MoO - thiamine selenouridine in tRNA acetyl phosphate citrate lyase acyl β-adenosylcobamide glutamine 2 ribotide phosphate a [ribosomal 34 a thiocarboxylated an N-formyl-L- sn-glycero-3- β-D-fructofuranose guanine 37 D-ribulose K349_RS0115300 5,10-methenyltetrahydrofolate 5'-phosphate 5'-nucleotidase: molybdopterin phosphate carrier protein: a sulfurated a 5-L-glutamyl- a uridine α-Kdo an unfolded histidinol molybdopterin (S)-3-hydroxy-(9Z) protein S12] an amino acid [SAMP] C- methionylaminoacyl- phospho-N- butanoyl-CoA phosphate 1-phosphate CTP Phe 1-phosphate thiamine phosphate dependent: K349_RS0102450 adenosylcobinamide- acetate kinase: K349_RS0108860 [sulfur carrier] [peptide] in tRNA in tRNA purine protein a 5,10- cofactor -octadecenoyl-CoA 3-hydroxy-9,10-secoandrosta- L-aspartate 89 terminal glycine tRNA (arachidonoyl) tRNA synthase: K349_RS0114335NAD(+) synthase: 1-(β-D GDP K349_RS0113655 histidinol methenyltetrahydrofolate a 5-methylaminomethyl- 1,3,5(10)-triene-9,17-dione [+ 4 isozymes] ethanolamine (guanosine(37)-N1) xanthine K349_RS0108810 K349_RS0114335 α α ribofuranosyl) ribazoletransferase: 34 3-hydroxyacyl-CoA 3-deoxy-manno- L-fuculose- chaperonin GroEL: dehydrogenase: bifunctional 5,10- Co -[ -(5- 2-selenouridine tRNA 2- phosphate class I fructose- -methyltransferase dehydrogenase: thioredoxin pathway nicotinate adenine nicotinamide K349_RS0103255 dehydrogenase: acetate oxaloacetate 30S ribosomal gamma- peptide octulosonate phosphate aldolase: K349_RS0111790 K349_RS0112505 NMN methylenetetrahydrofolate methylbenzimidazolyl)]- α α thiamine in tRNA thiouridine(34) butyryltransferase: bisphosphate TrmD: K349_RS0102505 thiamine dinucleotide β Co -[ -(benzimidazolyl) K349_RS0115345 protein S12 glutamyltransferase: deformylase: glycerophosphodiester cytidylyltransferase: K349_RS0111020 dehydrogenase/5,10- Co -adenosylcobamide bis(molybdenum β diphosphate synthase MnmA: K349_RS0108975 aldolase: K349_RS0108220 his phosphate an oxidized ]-Co -adenosylcobamide 3-oxo-(9Z)- 3,4-dihydroxy-9,10-secoandrosta- methylthiotransferase K349_RS0106760 K349_RS0115145 phosphodiesterase: K349_RS0111510 an N 1 - xanthine a protein methenyltetrahydrofolate cofactor) K349_RS0114510 K349_RS0109925 thioredoxin 5'-phosphate octadecenoyl-CoA 1,3,5(10)-triene-9,17-dione RimO: K349_RS0107405 K349_RS0101095 methylguanine 37 dehydrogenase: cyclohydrolase: molybdenum cofactor acetyl-CoA C- an α-(5-L- in tRNA Phe DHAP glycolaldehyde K349_RS0106250 nicotinate-nucleotide 10 K349_RS0114410 thiamine tRNA processing C1 Compound Utilization and Assimilation a L-methionylaminoacyl- butanoyl an N - guanylyltransferase: glutamyl)- a peptide a [SAMP] C- a 2-thiouridine 34 formate DHAP D-glyceraldehyde CMP-Kdo 8-hydroxypurine adenylyltransferase: pyridoxal 5'-phosphate biosynthesis II diphosphate acyltransferase: a [ribosomal tRNA sn-glycerol phosphate formyltetrahydrofolate K349_RS0108630 acyl carrier 5'-deoxyadenosine an unsulfurated amino acid terminal glycine in tRNA anandamide thiamine thioredoxin- K349_RS0114560 bis(guanylyl Coα-[α-(benzimidazolyl) salvage III a polycistronic K349_RS0109975 (1E,2Z)-3-hydroxy-5,9,17- formate assimilation into 5,10- met protein S12]-3- 3-phosphate phosphoribosylglycinamide protein activation formate [sulfur carrier] diphosphate disulfide reductase: NaMN molybdopterin) ]-Coβ-adenosylcobamide tRNA precursor trioxo-4,5:9,10-disecoandrosta- methylenetetrahydrofolate methylsulfanyl- formyltransferase: aldehydo-D-ribose D-glyceraldehyde gln thiamine (7Z)-hexadecenoyl-CoA oxidation to CO 89 K349_RS0113810 2 L-aspartate S-adenosyl- K349_RS0113100 5-phosphate 3-phosphate cofactor thiamine an apo acyl- 1 (10),2-dien-4-oate L-methionine guanylyl molybdenum diphosphokinase: carrier protein formate formate holo-[acyl-carrier- α a tetrahydrofolate cofactor biosynthesis formate-- UDP-N-acetyl-α-D-muramoyl- 10 34 α ε 2251 38- UDP- -D- biosynthesis pyridoxal 5'- K349_RS0112705 formate an L-methionyl- an N - a [protein]-S- a uridine N ,N -diacetyl-lysyl- guanosine a uridine 6,8- a [protein]- Fatty Acid and Lipid Biosynthesis a reduced thiamine protein] synthase: tetrahydrofolate L-alanyl-γ-D-glutamyl- acetoacetate succinyl-CoA H O leukotriene-D4 glucuronate palmitate biosynthesis II phosphate synthase: MoO - a tRNA precursor a tRNA precursor dehydrogenase D-alanyl-D-alanine Met formyltetrahydrofolate sulfanyl-L-cysteine in tRNA 2 D-alanyl-D-alanine in 23S rRNA 40 in tRNA dihydroxypurine L-histidine lipid IV biosynthesis (E. coli) thioredoxin 2 K349_RS0112895 (2E,7Z)- [initiator tRNA ] GTP hypoxanthine A met diphosphate 3-[(3aS,4S,7aS)-7a-methyl- ligase: meso-2,6-diaminopimelate RluA family xanthine bifunctional (bacteria and plant cytoplasm) K349_RS0105480 molybdopterin a holo acyl- with a 5' with a 5' hexadecenoyl-CoA (2Z,4Z)-2-hydroxyhexa- subunit alpha: 23S rRNA methionine 1,5-dioxo-octahydro-1H 10 K349_RS0105415 pseudouridine dehydrogenase: UDP-4-keto- histidine kinase: a (3R)-3- K349_RS0105485 cofactor molybdenum cofactor carrier protein extension and extension and a 2,4-dienoate an N - K349_RS18725 penicillin-binding membrane (guanosine(2251) xanthine adenosyltransferase: -inden-4-yl]propanoate tRNA 2- 3-oxoacid CoA- synthase: K349_RS0102505 pentose/UDP- K349_RS0104645 D-ribose RS0104365 D-ribose an acetoacetyl-[acp] hydroxytetradecanoyl- UDP-N-acetyl- guanylyltransferase: a long 3' trailer short 3' extension formyltetrahydrofolate CO UDP-N- methionyl-tRNA protein 2: dipeptidase: -2'-O)- dehydrogenase: K349_RS0112260 2 thiouridine(34) transferase GTPase HflX: xylose synthase: α guanylyl K349_RS0108630 ribonuclease P acetylmuramoyl- formyltransferase: methyltransferase K349_RS0107520 xanthine K349_RS0102505 a [protein]- [acp] -D-glucosamine SAM bifunctional 5,10- synthase MnmA: subunit B: K349_RS0113580 K349_RS0111905 K349_RS0104675 3-oxoacyl-[acyl- PLP molybdenum protein component: (S)-3-hydroxy-(7Z) tripeptide--D-alanyl- K349_RS0115140 RlmB: [+ 2 isozymes] dehydrogenase: xanthine K349_RS16650 N-phospho- biotin-carboxyl carrier cofactor methylenetetrahydrofolate K349_RS0114510 K349_RS0109980 [+ 3 isozymes] a pseudouridine 38- UDP-α-D-xylose L-histidine carrier-protein] acyl-ACP--UDP-N- ribonuclease PH: K349_RS0112545 -hexadecenoyl-CoA (S)-4-hydroxy-2-oxohexanoate 3-[(3aS,4S,7aS)-7a-methyl- D- alanine ligase: 2-O- K349_RS17250 K349_RS0106250 dehydrogenase: protein assembly a tRNA precursor dehydrogenase/5,10- Nα,Nε-diacetyl- 40 in tRNA 2+ 2+ reductase: acetylglucosamine K349_RS0109485 3-hydroxyacyl-CoA 1,5-dioxo-octahydro-1H- K349_RS17405 an N-formyl- 2251 urate K349_RS0106250 Mg RS0101365 Mg methenyltetrahydrofolate + leukotriene-E4 methylguanosine 6,8- with a short inden-4-yl]propanoyl-CoA a tetrahydrofolate a [protein]- a 2-thiouridine 34 phosphate H lysyl-D-alanine D-ala gly K349_RS0113695 O-acyltransferase: a [biotin carboxyl- dehydrogenase: cyclohydrolase: L-methionyl- acetoacetyl-CoA succinate GDP in 23S rRNA dihydroxypurine a (3R)-3- a tRNA 3' extension met L-cysteine in tRNA K349_RS0111470 carrier protein]-L-lysine K349_RS0115345 K349_RS0114410 UDP-N-acetyl-α-D-muramoyl-L- [initiator tRNA ] hydroxybutanoyl- precursor with biotin--[acetyl-CoA- 3-oxo-(7Z)- alanyl-γ-D-glutamyl-meso-2,6- [acp] UDP-3-O-[(3R)-3- Amino Acid Biosynthesis a 5' extension a 5,10- folate RS0109855 folate carboxylase] ligase: ribonuclease PH: hexadecenoyl-CoA 1-propanal pyruvate 5-hydroxy-3-[(3aS,4S,5R,7aS)- diaminopimeloyl-D-alanyl-D-alanine 3-hydroxyacyl-ACP hydroxymyristoyl]-N- Aromatic Compound Biosynthesis methenyltetrahydrofolate K349_RS0114425 K349_RS0109485 acetyl-CoA C- 7a-methyl-1,5-dioxo-octahydro- dehydratase FabZ: acetyl-α-D-glucosamine L-histidine biosynthesis ribonuclease P propanal bifunctional 5,10- a [biotin carboxyl- superpathway of branched chain amino acid biosynthesis L-tryptophan biosynthesis L-isoleucine L-homocysteine biosynthesis glycine biosynthesis I acyltransferase: 1H-inden-4-yl]propanoyl-CoA α a [protein] N- K349_RS0111465 UDP-3-O-[3- protein component: dehydrogenase: methylenetetrahydrofolate UDP-N-acetyl- -D-muramoyl- N-acetyl-D-glucosaminyl-N- a peptidoglycan a [protein]-α- dCDP carrier protein]-N biosynthesis IV chorismate biosynthesis I K349_RS0109975 di-trans,octa-cis- γ a proteinogenic glutathione a 3-oxo acid succinyl-CoA H O terminal-formyl- a RNA-DNA hybrid 5-MTR-1-P L,L- roseoflavin hydroxymyristoyl] N- dipicolinate biosynthesis K349_RS0112545 dehydrogenase/5,10- L-alanyl- -D-glutamyl-L- acetylmuramoyl-L-alanyl-D-glutamyl- 2 dimer (S. aureus) L-glutamate Cd 2+ RS0106625 Cd 2+ a (2E)-but- 6 -biotinyl-L-lysine PRPP K349_RS0102275 undecaprenyl phosphate amino acid ATP diaminopimelate riboflavin vitamin B12- acetylglucosamine pyruvate thr chorismate L-homoserine ser methenyltetrahydrofolate lysyl-D-alanyl-D-alanine 6-carboxy-L-lysyl-D-alanine L-methionine protein-glutamate O- S-methyl-5- diaminopimelate 2-enoyl-[acp] propanoate D-erythrose (5Z)-tetradecenoyl-CoA biosynthesis dependent deacetylase: ATP serine 4-phosphate propanoyl-CoA (2E)-3-[(3aS,4S,5R,7aS) cyclohydrolase: penicillin-binding methyltransferase thioribose-1- epimerase: ribonucleotide crotonyl-[acyl- biosynthetic-type anthranilate asp 3-oxoacid CoA- protein RibF: K349_RS0111460 phosphoribosyltransferase: threonine/serine homoserine O- hydroxymethyltransferase: 3-deoxy-7- -5-hydroxy-7a-methyl-1- K349_RS0114410 phospho-N- gamma- protein 2: peptide ribonuclease HII: CheR: phosphate K349_RS0108900 reductase: carrier-protein] UDP-3-O-(3- a [biotin carboxyl- acetolactate synthase: phosphoheptulonate an uncharged oxo-octahydro-1H-inden- LD-carboxypeptidase: transferase ATPase: K349_RS0111120 K349_RS0114720 K349_RS0114840 K349_RS0112495 dehydratase: acetyltransferase: K349_RS0108145 aspartate kinase: a 5,10- acetylmuramoyl- glutamyltransferase: K349_RS0111905 deformylase: a [protein]-L- isomerase: diaminopimelate K349_RS0104825 AI-2 RS0103975 AI-2 reductase: hydroxymyristoyl) carrier-protein dimer]- synthase: K349_RS18515 propanoyl-CoA synthase: tRNA 4-yl]prop-2-enoyl-CoA K349_RS0110325 subunit B: K349_RS0113740 roseoflavin 1-(5-phospho- K349_RS0101695 K349_RS0109350 serine K349_RS0111740 methylenetetrahydrofolate pentapeptide- K349_RS0106760 K349_RS0115145 glutamate-O 5 5-(methylsulfanyl)K349_RS0115235 epimerase: K349_RS0113695 -α-D-glucosamine N 6 -biotinyl-L-lysine K349_RS0103095 K349_RS0103650 (2E,5Z)- K349_RS0109980 [+ 3 isozymes] 5'-phosphate CDP β-D-ribosyl)-ATP threonine/serine anthranilate O-acetyl-L- hydroxymethyltransferase: glyA 3-deoxy- L-aspartyl- transferase: a peptidoglycan -methyl-ester -ribulose 1- K349_RS0110365 UDP-3-O-(3- K349_RS0103130 2-oxoacid:ferredoxin tetradecenoyl-CoA N-acetyl-D-glucosaminyl-N- a nucleoside 5'- 2,3,4-saturated fatty biotin carboxylase: bifunctional dehydratase: oxidoreductase homoserine hydrogen sulfide gly D-arabino- 4-phosphate Amine and Polyamine K349_RS0114680 an α-(γ-L-glutamyl) with D,D cross- D-ala an N-terminal L- DNA phosphate meso- hydroxymyristoyl) anthranilate acetylmuramoyl-L-alanyl-D- a 2,3,4-saturated H + monophosphate acyl-[acp]:NAD+ K349_RS0109760 (S)-2-acetolactate K349_RS0103265 heptulosonate 3-[(3aS,4S,5R,7aS)-5- Degradation D-ala L-cysteinylglycine succinate phosphate link (S. aureus) formate diaminopimelate Peptide RS0100885 Peptide glucosamine N- phosphoribosyl- phosphoribosyltransferase: subunit gamma: aspartate- glutamyl-6-carboxy-L-lysine -L-amino acid 3-oxoacyl-CoA ADP methionyl-[protein] oxidoreductase: a [carboxyl-carrier AMP cyclohydrolase/ K349_RS0115115 7-phosphate queuosine hydroxy-7a-methyl-1-oxo- undecaprenyl-diphospho-N- UMP 6 (2Z)-2-aminobut- O-acetylhomoserine semialdehyde N-acetylglucosamine K349_RS0113685 acyltransferase: protein dimer]-N - ketol-acid K349_RS18515 3-dehydroquinate biosynthesis I (de novo) octahydro-1H-inden-4-yl]- acetylmuramoyl-L-alanyl-γ-D- phosphoribosyl- 2-enoate [+ 2 isozymes] aminocarboxypropyltransferase/ L-glutamine dehydrogenase: degradation I K349_RS0111455 carboxybiotinyl-L-lysine reductoisomerase: N-(5-phosphoribosyl) synthase: (3E,5Z)-tetradeca- (S)-3-hydroxy-(5Z) 3-hydroxypropanoyl-CoA glutamyl-L-lysyl- D-alanyl-D-alanine UDP-2-N,3-O-bis[(3R)- ATP diphosphatase cysteine synthase: biosynthesis I K349_RS0111745 a butanoyl-[acp] K349_RS0103125 -anthranilate 2-oxobutanoate K349_RS0103670 preQ 3,5-dienoyl-CoA -tetradecenoyl-CoA 3-hydroxyacyl-CoA N-acetyl-D- 3-hydroxytetradecanoyl]- HisIE: 0 (2R)-2,3- K349_RS0100940 L-aspartate 4- acyl-CoA 3-hydroxyacyl-CoA dehydrogenase: glucosamine α-D-glucosamine K349_RS0112470 phosphoribosylanthranilate 3-dehydroquinate UDP-N-acetyl-α-D- an sn-glycero-3- (E)-4-hydroxy-3- D-firefly a [protein]-L- UDP-4-amino- UDP beta-ketoacyl- dihydroxy-3- biosynthetic-type glu semialdehyde thioesterase: dehydrogenase: K349_RS0115345 6-phosphateN-acetylglucosamine- di-trans,octa-cis- coenzyme A an apo [peptidyl- glutathione a D-aminoacyl- a tripeptide H O pyruvate isomerase: K349_RS16280 muramoyl-L-alanyl-γ-D- hypoglycin A phospho-N-(acyl) methylbut-2-en- 2 ω D-fucose thr ACP synthase II: UDP-2,3- 1-(5-phospho-β- methylbutanoate 2-iminobutanoate acetolactate glutamine K349_RS0111090 K349_RS0115345 3-[(3aS,4S,5R,7aS)-5-hydroxy- undecaprenyl phosphate carrier protein] [tRNA] luciferyl-CoA proline ( = 180) vitamin B12- 1-(2- L-homocysteine type I 3- 4-hydroxy- preQ 6-phosphate glutamyl-L-lysyl-D-alanine ethanolamine 1-yl diphosphate peptidyl-prolyl cis- UDP-4-amino-4, 6- pyruvate K349_RS0113705 diacylglucosamine acyl-CoA hydrolysis D-ribosyl)-AMP dihydroxy-acid synthase: synthetase: 1 7a-methyl-1-oxo-octahydro-1H- flavodoxin- threonine/serine dependent carboxyphenylamino) dehydroquinate tetrahydrodipicolinate (3E,5Z)- 3-oxo-(5Z)- deacetylase: trans isomerase: dideoxy-N-acetyl- carboxylase diphosphatase: bifunctional dehydratase: K349_RS0103095 K349_RS0107885 tRNA guanosine(34) inden-4-yl]-3-oxopropanoyl-CoA dependent (E)-4- acyl-CoA dehydratase: ribonucleotide a 3-oxohexanoyl- -1-deoxy-D-ribulose gln dehydratase: synthase: tetradecadienoate tetradecenoyl-CoA D-glucosamineK349_RS0105735 holo-[acyl-carrier- gamma- glycerophosphodiester D-tyrosyl-tRNA(Tyr) peptidase T: K349_RS0108170 beta-L-altrosamine subunit B: K349_RS0101015 a 2,3,4-saturated phosphoribosyl- K349_RS0103075 K349_RS0103130 transglycosylase phospho-N- hydroxy-3-methylbut- thioesterase: K349_RS0101695 reductase: [acp] 5-phosphate K349_RS0103675 K349_RS0106805 acetyl-CoA C- 6-phosphate protein] synthase: glutamyltransferase: phosphodiesterase: deacylase: K349_RS0100200 [+ 2 isozymes] transaminase: K349_RS0113960 fatty acyl CoA AMP cyclohydrolase/ 3-methyl-2- (2S,4S)-4- Tgt: acetyl-CoA C- acetylmuramoyl- 2-enyl-diphosphate K349_RS0111090 threonine/serine K349_RS0104825 3-oxoacyl-[acyl- lipid X acyl-CoA 2-oxobutanoate indole-3-glycerol (S)-2-aceto-2- acyltransferase: K349_RS0112895 K349_RS0106760 K349_RS0101095 K349_RS0111875 a [protein]-L- K349_RS0112370 oxaloacetate phosphoribosyl- oxobutanoate hydroxy-2,3,4,5- acyltransferase: pentapeptide- synthase: ω UDP-4-dehydro- thioesterase: phosphate hydroxybutanoate 3-dehydroshikimate K349_RS0111970 K349_RS0109975 proline ( = 0) dehydratase: dUDP carrier-protein] lipid A disaccharide ATP diphosphatase tetrahydrodipicolinate a 7-aminomethyl-7- K349_RS0109975 transferase: 2-C-methyl-D-K349_RS0114285 6-deoxy-α- K349_RS0111090 biosynthetic-type synthase TrpC: 2-aceto-2-hydroxy- (3Z)-dodec- a proteinogenic K349_RS0103265 reductase: a 2,3,4-saturated shikimate 34 α K349_RS0114680 a holo [peptidyl- a dipeptide D-firefly luciferin synthase: HisIE: 2-isopropylmalate branched-chain- acetolactate butanoate L-cysteine biosynthesis I deazaguanosine 3-[(3aS,4S,5R,7aS)-5-hydroxy- -D-glucosamine 3',5'-ADP sn-glycerol an N- an uncharged erythritol-2,4- D-glucose 2-oxobutanoate K349_RS0113695 fatty acid K349_RS0103720 dehydrogenase: 3-enoyl-CoA carrier protein] hypoglycin B L-cysteinylglycine a D-amino acid amino acid a (3R)-3- K349_RS0111490 K349_RS0112470 synthase: amino-acid synthase: isomeroreductase: L-alanine in tRNA acetyl-CoA 7a-methyl-1-oxo-octahydro- 6-phosphate 3-phosphate acylethanolamine tRNA cyclodiphosphate lipid A disaccharide 1-(5-phospho-β-D-ribosyl)- K349_RS0103120 transaminase: K349_RS0103095 (1S,2R)-1-C-(indol-3- biosynthesis III K349_RS0103680 tRNA preQ1(34) S- glucosamine- undecaprenyl-diphospho-N UMP hydroxyhexanoyl- K349_RS0103125 dipicolinate 1H-indene-4-carboxyl-CoA γ (E. coli) 5-[(5-phosphoribosylamino) K349_RS0108990 yl)glycerol 3-phosphate ser adenosylmethionine -acetylmuramoyl-L-alanyl- - [acp] K349_RS0103130 (R)-2,3-dihydroxy- shikimate 6-phosphate methylideneamino]imidazole- (2S)-2- serine acetyltransferase: ribosyltransferase- D-glutamyl-L-lysyl- D-alanine 3-hydroxyacyl-ACP tetraacyldisaccharide (S)-2-aceto-2- tryptophan synthase 3-methylpentanoate cys (2E)-dodec- deaminase: 4'-kinase: 4-carboxamide isopropylmalate subunit beta: K349_RS0107610 isomerase QueA: 2-enoyl-CoA K349_RS0105730 dehydratase FabZ: hydroxybutanoate dihydroxy-acid cysteine shikimate kinase: val K349_RS0114370 (5R,7aS)-5-hydroxy-7a-methyl- 2503 UDP-N-acetyl- K349_RS0111465 K349_RS0111505 1-(5-phosphoribosyl) 3-isopropylmalate K349_RS0100705 O-acetyl-L-serine desulfurase NifS: K349_RS0103670 adenine an apo-[LYS2 L- RNase III mRNA a dipetide with an N- a long-chain a uridine 55 a uracil 1939 UTP ketol-acid dehydratase: 1-oxo-3,5,6,7-tetrahydro- F6P coenzyme A coenzyme A carbamoyl H O an acyl-CoA H O α precorrin-6B -5-[(5- dehydratase an epoxyqueuosine 34 in 23S rRNA 2-aminoadipyl- VibB processing L-ornithine fatty acyl-CoA 2 2 -D-muramate a (2E)-hex- lipid IV (E. coli) reductoisomerase: tryptophan synthase: K349_RS0103075 K349_RS0111070 shikimate 3- 2H-indene-4-carboxyl-CoA phosphate terminal L-aspartate in tRNA UDP-N- in 23S rRNA anaerobic A phosphoribosylamino) large subunit: O-acetylhomoserine carrier-protein] substrate tRNA 23S rRNA precorrin-6A/ 2-enoyl-[acp] K349_RS0103125 K349_RS0103705 ala in tRNA ribonucleoside- methylideneamino] K349_RS0108845 (S)-3-methyl-2- aminocarboxypropyltransferase/ phosphate (S)-3- pseudouridine(55) acetylmuramate (uracil(1939)-C(5)) cobalt-precorrin- (R)-2,3-dihydroxy- K349_RS0103710 epoxyqueuosine 23S rRNA acyl-CoA acyl-CoA dehydrogenase: triphosphate hexanoyl-[acyl- imidazole-4- oxopentanoate cysteine synthase: 3-phosphoshikimate 1- hydroxydodecanoyl-CoA holo-[acyl-carrier- holo-[acyl-carrier- ornithine dipeptidase: synthase TruB: -methyltransferase 6A reductase: [+ 3 isozymes] 3-methylpentanoate ser reductase QueH: (adenine(2503)-C(2) ribonuclease III: thioesterase: thioesterase: K349_RS0114655 reductase: carrier-protein] phosphatidylglycerol carboxamide isomerase: indole branched-chain- K349_RS0100940 carboxyvinyltransferase: 3-hydroxyacyl-CoA (5R,7aS)-7a-methyl-1,5- protein] synthase: protein] synthase: carbamoyltransferase: K349_RS0106350 K349_RS0114845 RlmD: K349_RS0102055 glycine K349_RS0107690 )-methyltransferase K349_RS0113710 K349_RS0111090 K349_RS0111090 55 UDP-N-acetyl-α- K349_RS0108060 reductase: biosynthesis II (non-plastidic) K349_RS0112480 2-isopropylmaleate dihydroxy-acid amino-acid K349_RS0103660 dehydrogenase: dioxo-3,5,6,7-tetrahydro- K349_RS0112895 K349_RS0112895 a pseudouridine K349_RS0112990 cysteine synthase biosynthesis IV a queuosine 34 RlmN: K349_RS0114300 D-glucosamine- a 5- precorrin-6A K349_RS0113695 dehydratase: transaminase: 5-enolpyruvoyl- K349_RS0115345 2H-indene-4-carboxyl-CoA in tRNA dUTP tryptophan synthase A: K349_RS0107605 in tRNA enolpyruvate methyluracil 1939 DHAP phosphoribulosylformimino- 3-isopropylmalate K349_RS0103075 K349_RS0108990 shikimate 3- K349_RS18685 a holo-[LYS2 L- a long-chain 2,3,4-saturated fatty subunit beta: a holo-[VibB aryl- RNase III a proteinogenic asp a carboxylate in 23S rRNA AICAR-phosphate dehydratase thr phosphate 3-oxododecanoyl-CoA 3',5'-ADP 2-aminoadipyl- 3',5'-ADP an mRNA fragment fatty acid acyl-[acp]:NAD+ (S)-3-methyl-2- K349_RS0100705 cys low-specificity L- carrier protein] processing L-citrulline amino acid large subunit: chorismate 2503 carrier-protein] oxidoreductase: oxopentanoate ile acetyl-CoA C- (3R)-2-(2-carboxyethyl)- a 2-methyladenine product mRNA imidazole glycerol K349_RS0108845 tryptophan synthase: threonine aldolase: synthase: 5'-deoxyadenosine K349_RS0113685 sn-glycerol branched-chain- acyltransferase: 3-methyl-6-oxocyclohex- in 23S rRNA met phosphate synthase: K349_RS0103705 K349_RS0109505 K349_RS0103665 lipoprotein posttranslational 3-phosphate [+ 3 isozymes] amino-acid K349_RS0109975 1-ene-1-carboxyl-CoA K349_RS0112475 K349_RS0103710 gly modification a hexanoyl-[acp] glycerol-3- (2R,3S)-3- transaminase: L-selenocysteine biosynthesis I (bacteria) K349_RS0112485 chorismate phosphate 1-O- isopropylmalate a [prolipoprotein]- decanoyl-CoA 6 K349_RS0108990 an N -L- 3-aci- a peptide with a uridine 13 a uracil 1498 a [protein]-L- a phosphate CTP L-cysteine a sulfurated 37 coenzyme A an apo-[aryl- glycerophosphoserine A ammonium H O canavaninosuccinate beta-ketoacyl- acyltransferase isocitrate/ threonylcarbamoyladenine an N-terminal 2 hydantoin D-erythro-1- trp sec nitropropanoate in tRNA in 16S rRNA β-isoaspartate ACP synthase II: ser a tRNA 9-carboxy-6-methyl-3,7- [sulfur carrier] carrier protein] monoester anaerobic PlsY: AICAR (imidazol-4- isopropylmalate ile prolipoprotein in tRNA Xaa-L-proline hydantoinase/ tRNA 16S rRNA protein-L- K349_RS0113705 selenide dioxononanoyl-CoA alkaline ribonucleoside- K349_RS0108185 yl)-glycerol dehydrogenase uracil degradation diacylglyceryl oxoprolinase pseudouridine(13) (uracil(1498)-N(3))- isoaspartate(D- a 1-acyl-sn family protein: transferase: nitronate glycerophosphodiester hydroxylamine argininosuccinate phosphatase: triphosphate a 3-oxooctanoyl- 3-phosphate I (reductive) serine--tRNA ligase: selenide, water (2E)-dec-2-enoyl-CoA tRNA (N(6)-L- holo-[acyl-carrier- leucyl family protein: synthase TruD: methyltransferase: aspartate) O- -glycerol 3- K349_RS16235 K349_RS0112565 acetyl-CoA C- monooxygenase: phosphodiesterase: reductase: lyase: K349_RS0105460 reductase: [acp] imidazoleglycerol- dikinase SelD: protein] synthase: aminopeptidase: K349_RS0105220 K349_RS17945 3 K349_RS0108095 methyltransferase: K349_RS0114980 threonylcarbamoyladenosine(37) 13 an N - K349_RS0108060 phosphate uracil a [prolipoprotein]- acyltransferase: K349_RS0112895 K349_RS0102825 K349_RS0101095 K349_RS0110640 K349_RS0112650 a pseudouridine K349_RS0113355 an alcohol 3-oxoacyl-[acyl- phosphate (2S)-2-isopropyl- K349_RS17370 K349_RS0109975 -C(2))- methylthiotransferase K349_RS0107595 [+ 2 isozymes] methyluracil 1498 a protein L-β- 1-acyl-sn-glycerol- dehydratase: 3-oxosuccinate L-homoserine S-1,2-diacyl-sn- in tRNA dCTP carrier-protein] 3-phosphate biosynthesis an L-seryl- glyceryl-L-cysteine MtaB: K349_RS0108090 [unspecified N-carbamoylglycine in 16S rRNA isoaspartate K349_RS0112490 sec selenophosphate sn-glycerol reductase: [tRNA ] (S)-3- 7-carboxy-4-methyl- 3',5'-ADP a holo-[aryl- 3-oxopropanoate nitrite degradation a peptide with hydroxylamine L-canavanine fumarate α-methyl ester acyltransferase: 3-(imidazol-4- 5,6-dihydrouracil acetyl-CoA 3-phosphate ser a proteinogenic K349_RS0113695 signal peptidase II: a 2-methylsulfanyl-N 6 -L- carrier protein] an N-terminal K349_RS0107695 yl)-2-oxopropyl asp hydroxydecanoyl-CoA 5-oxoheptanoyl-CoA products] amino acid a (3R)-3- 37 5'-deoxyadenosine an unsulfurated 4-methyl-2- hydantoinase/ L-seryl-tRNA(Sec) K349_RS0101260 3-hydroxyacyl-CoA threonylcarbamoyladenine met L-proline hydroxyoctanoyl- 1-acyl-sn-glycerol- phosphate aspartate kinase: [sulfur carrier] 3-phosphate histidinol-phosphate oxopentanoate oxoprolinase selenium dehydrogenase: in tRNA [acp] K349_RS0111740 family protein: an (S-diacyl- a lipoprotein K349_RS0115345 3-hydroxyacyl-ACP acyltransferase: transaminase: branched-chain- transferase: L-aspartyl- K349_RS0105220 sn-glyceryl) signal peptide (2E)-7-carboxy-4-methyl- dehydratase FabZ: K349_RS0113575 K349_RS0114250 amino-acid K349_RS0113505 N 6 -dimethylallyladenosine 37 a peptidoglycan dimer (meso a 2,3,4-saturated a DNA with an insertion sequence a 1,2-diacyl- L-tyrosine 4-phosphate -L-cysteinyl- 3-oxodecanoyl-CoA 5-oxohept-2-enoyl-CoA a sulfurated coenzyme A AsbD acyl- a uracil in DNA aci-nitroethane a ribonucleoside precorrin-6B α-amylose K349_RS0111465 histidinol-phosphate transaminase: [+ 2 isozymes] in tRNA -diaminopimelate containing) 1,2-diacyl-sn- hypoxanthine D-ala element IS30 lys sn-glycerol biosynthesis I an L- [apolipoprotein] [sulfur carrier] carrier protein diphosphate 1,4-alpha-glucan transaminase: K349_RS0108990 aspartate- acetyl-CoA C- glycerol 3-phosphate CTP vitamin B12- transposase: precorrin-6y C5,15- a (2E)-oct- 3-phosphate 3-ureidopropanoate selenocysteinyl- D-alanine--D- branching lysine 2,3- K349_RS0108935 semialdehyde acyltransferase: penicillin-binding dependent K349_RS15890 methyltransferase 2-enoyl-[acp] phosphatidate chorismate [tRNA sec ] DNA-deoxyinosine uracil-DNA nitronate alanine ligase: protein GlgB: aminomutase: leu dehydrogenase: a peptide K349_RS0109975 (3R)-7-carboxy-3-hydroxy-4- tRNA (N6-isopentenyl holo-[acyl-carrier- protein 2: phosphatidate ribonucleotide (decarboxylating) cytidylyltransferase: L-histidinol chorismate mutase: an N-acyl-(S- glycosylase: glycosylase: monooxygenase: K349_RS0111710 [+ 9 isozymes] K349_RS0107270 K349_RS0105260 octanoyl-[acyl- K349_RS0111745 superpathway of L-asparagine biosynthesis methyl-5-oxoheptanoyl-CoA adenosine(37)-C2)- protein] synthase: K349_RS0111905 cytidylyltransferase: reductase: an insertion subunit CbiE: K349_RS0114270 phosphate K349_RS0103700 diacyl-sn-glyceryl) octanoyl-CoA K349_RS0101945 K349_RS0114260 K349_RS0102825 carrier-protein] 3-hydroxyacyl-CoA methylthiotransferase K349_RS0112895 K349_RS0114270 K349_RS0104825 D-alanyl-D-alanine sequence IS30 with K349_RS17670 amylopectin L-β-lysine L-threonine L-aspartate 4- -L-cysteinyl- a 2'- reductase: a CDP- prephenate dehydrogenase: MiaB: K349_RS0107665 integrated transposon precorrin-8x biosynthesis semialdehyde β-alanine alanine [lipoprotein] a peptidoglycan with deoxyribonucleoside K349_RS0113695 diacylglycerol asp K349_RS0115345 an apurinic site an apyrimidinic uracil prephenate homoserine racemization 3',5'-ADP a holo-[AsbD acyl- D,D cross-links (meso- D-ala a CDP-2,3,4-saturated- acetaldehyde nitrite 5'-diphosphate CDP-diacylglycerol-- 6 within DNA hypoxanthine site in DNA 2,3,4-saturated fatty L-homoserine dehydrogenase/ dehydrogenase: 7-carboxy-4-methyl-3,5- 2-methylsulfanyl-N - carrier protein] diaminopimelate containing) diacylglycerol histidinol 37 an unsulfurated acyl-[acp]:NAD+ glycerol-3-phosphate 3- (2E)-oct-2-enoyl-CoA dioxoheptanoyl-CoA 5'-deoxyadenosine dimethylallyladenosine met homoserine kinase: arogenate K349_RS0102675 ala asparagine synthase asparagine synthase [sulfur carrier] oxidoreductase: phosphatidyltransferase: 6 37 in tRNA histidinol K349_RS0111735 dehydrogenase alanine racemase: (glutamine-hydrolyzing) (glutamine-hydrolyzing) N -L-threonylcarbamoyladenosine K349_RS0113685 K349_RS0108025 L-homoserine acetyl-CoA C- 1-(3-sn- dehydrogenase: O-phospho- family protein: L-glutamate K349_RS0107740 : K349_RS0106970 : K349_RS0110570 -modified tRNA biosynthesis K349_RS0112505 L-homoserine K349_RS17755 acyltransferase: phosphatidyl) biosynthesis III [+ 2 isozymes] asparagine synthase asparagine synthase an N 3 -methyladenine (+)-7-epi- (S)-4-amino-5- 5-androstene- an octanoyl-[acp] 3-(4- K349_RS0109975 methanethiol O-acetyl-L- coenzyme A [EntF L-seryl- an adenosine 37 glycerophosphoglycerol H O a DNA segment a ribonucleoside [DNA] threonine synthase: D-ala (glutamine-hydrolyzing) (glutamine-hydrolyzing) (S)-3- DMAPP 2 an acyl phosphate lys -sn-glycerol histidinal ATP homoserine carrier protein] in DNA jasmonoyl-CoA triphosphate oxopentanoate 3,17-dione K349_RS0111730 hydroxyphenyl) 2-oxoglutarate : K349_RS0110570 : K349_RS0106970 thr hydroxyoctanoyl-CoA in tRNA recombinase RecA: glutamate-1- DNA polymerase beta-ketoacyl- 3-phosphate 5-carboxy-2-methyl- anaerobic steroid Delta- histidinol pyruvate NADP-specific 3-hydroxyacyl-CoA acetyl-CoA K349_RS0107385 ribonucleoside- acylphosphatase: semialdehyde III subunit beta: L-lysine 6- ACP synthase II: phosphatidylglycerophosphatase threonine synthase: 3-oxopentanoyl-CoA glycerophosphodiester DNA-3- acyl-CoA isomerase: dehydrogenase: glutamate dehydrogenase: O-acetylhomoserine holo-[acyl-carrier- tRNA (adenosine(37)-N6) DDE-type integrase/ triphosphate K349_RS0104770 2,1-aminomutase: K349_RS0102845 transaminase: K349_RS0113705 A: K349_RS0107400 K349_RS0113270 threonylcarbamoyl- phosphodiesterase: methyladenine thioesterase: K349_RS0104995 K349_RS0112505 dehydrogenase: asn asn K349_RS0115345 aminocarboxypropyltransferase/ protein] synthase: -dimethylallyltransferase transposase/ reductase: K349_RS0102090 [+ 2 isozymes] K349_RS0112240 a 3-oxodecanoyl- an L-1- AMP synthase: K349_RS0101095 glycosylase I: K349_RS0111090 androst-4-ene- thr K349_RS0105360 cysteine synthase: K349_RS0112895 MiaA: K349_RS0115160 recombinase: K349_RS0108060 a carboxylate a nucleoside 5'- allysine [acp] phosphatidyl- K349_RS0111975 3-oxooctanoyl-CoA K349_RS0100075 a 2'- 5-aminolevulinate 3,17-dione his tyr glu K349_RS0100940 K349_RS18080 monophosphate sn-glycerol a holo-[EntF a DNA segment in deoxyribonucleoside 3-oxoacyl-[acyl- acetyl-CoA C- propanoyl-CoA succinyl-CoA 6 37 glycerol sn-glycerol (+)-7-epi- (L-threonylcarbamoyl) 3',5'-ADP L-seryl-carrier N -dimethylallyladenosine reverse orientation 5'-triphosphate carrier-protein] acyltransferase: 3-phosphate an apurinic site jasmonate adenylate acetate met protein] in tRNA 3-methyladenine reductase: K349_RS0109975 within DNA K349_RS0113695 tRNA (adenosine(37)-N6)- a (3R)-3- threonylcarbamoyltransferase hexanoyl-CoA hydroxydecanoyl- complex: K349_RS18205 stearate biosynthesis Carbohydrate Degradation sn-glycero-3- UDP-2-acetamido-4- a guanine 527 adenosyl-cob(III) a supercoiled a (1->4)- [acp] K349_RS18210 coenzyme A [EntB aryl- glycyl-glycine glutathione a peptide with a propanoyl-CoA H O D-threo-isocitrate α II (bacteria and plants) meso-diaminopimelate UDP-N-acetyl-α-D-muramoyl- phosphoethanolamine 2 amino-2,4,6-trideoxy- in 16S rRNA yrinate a,c-diamide pro duplex DNA -D-glucan 3-hydroxyacyl-ACP tRNA (adenosine(37)-N6)- carrier protein] leader sequence α 1,4-alpha-glucan UDP-N-acetyl-D- Carbohydrate Biosynthesis L-alanyl-D-glutamate -D-galactoseUDP-4-amino-4, 6- 16S rRNA cobyric acid NADP-dependent pyrroline-5- replicative dehydratase FabZ: CMP-pseudaminate GDP-mannose biosynthesis dTDP-L-rhamnose GDP-L-fucose threonylcarbamoyltransferase D-galactose degradation I (Leloir pathway) branching a palmitoyl-[acp] glucosamine biosynthesis I D-mannose degradation dideoxy-N-acetyl- (guanine(527)-N(7) synthase: isocitrate carboxylate DNA helicase: K349_RS0111465 biosynthesis biosynthesis biosynthesis I (from complex transferase subunit trans-hex-2-enoyl-CoA glycogen degradation II gamma- glycerophosphodiester acyl-CoA protein GlgB: beta-ketoacyl- UDP-N-acetylmuramoyl- holo-[acyl-carrier- beta-L-altrosamine )-methyltransferase K349_RS0102085 dehydrogenase: reductase: K349_RS0107960 a (2E)-dec- D-glucopyranose D-glucopyranose α GDP-D-mannose) TsaD: K349_RS0111780 β glutamyltransferase: phosphodiesterase: signal peptidase I: thioesterase: K349_RS0107270 ACP synthase II: UDP-N-acetyl- -D- GDP-α-D- -D-galactopyranose D-mannopyranose L-alanyl-D-glutamate-- protein] synthase: transaminase: RsmG: K349_RS0101705 K349_RS0105350 a single 2-enoyl-[acp] 6-phosphate α-D-glucosamine 6-phosphate an N 6 -L- a glycogen 6-phosphate K349_RS0112895 K349_RS0106760 K349_RS0101095 K349_RS0111110 K349_RS0111090 K349_RS0103365 adenosylcobyrate (S)-1-pyrroline- starch glucose-6- glucose-6- glucopyranose K349_RS0112370 7 2-oxoglutarate K349_RS0113705 UDP-N- mannose 37 galactose mannose-1-phosphate 2, 6-diaminopimelate UDP-2-acetamido- an N - stranded DNA a 3-oxooctadecanoyl- phosphate phosphate 1-phosphate GDP-mannose threonylcarbamoyladenine 5-carboxylate decanoyl-[acyl- acetylglucosamine glucose-1-phosphate mutarotase: guanylyltransferase/ ligase: K349_RS18895 2,6-dideoxy-α-D- methylguanine 527 [acp] isomerase: isomerase: 4,6-dehydratase: in tRNA (S)-3- γ-L-glutamyl- carrier-protein] 4,6-dehydratase thymidylyltransferase: K349_RS0109345 mannose-6- a holo-[EntB aryl- L-cysteinylglycine ethanolamine sn-glycerol propanoate xylo-hex-4-ulose in 16S rRNA K349_RS0115725 K349_RS0115725 K349_RS0111590 hydroxyhexanoyl-CoA 3',5'-ADP glycylglycine reductase: 3-oxoacyl-[acyl- (inverting): K349_RS0111605 GDP-4-dehydro- phosphate isomerase: UDP-N-acetyl-α-D-muramoyl-L-alanyl- carrier protein] 3-phosphate a leader sequence a peptide dTDP-α-D-glucose 3-hydroxyacyl-CoA α α K349_RS0113695 carrier-protein] glucose-6- K349_RS0112330 glucose-6- α-D-rhamnose -D-galactopyranose an -limit dextrin γ UDP-2-acetamido- dehydrogenase: K349_RS0104260 -D-glutamyl-meso-2,6-diaminopimelate 2,3,4-saturated fatty reductase: fatty acid elongation -- saturated phosphate phosphate dTDP-glucose GDP-L-fucose F6P 2,6-dideoxy-β-L- 5-oxo-L-proline metabolism K349_RS0115345 galactokinase: 4-alpha- acyl-[acp]:NAD+ K349_RS0113695 isomerase: isomerase: 4,6-dehydratase: synthase: a (3R)-3- arabino-hex-4-ulose K349_RS0109340 glucanotransferase: an N 10 - a DNA containing a 2'- dihomo γ- a cytidine 1402 a double-stranded (R)-2- pregn-5-ene- cholest-5- oxidoreductase: K349_RS0113885 K349_RS0113885 K349_RS0111615 K349_RS0111595 a [protein] with a [protein] with 3-oxohexanoyl-CoA AICAR a proteinogenic leukotriene-C4 3-methyl-2-oxobutanoate H O a cytosine in DNA hydroxyoctadecanoyl- an acetoacetyl-[acp] UDP-4-amino-4, 6- K349_RS0107265 formyltetrahydrofolate an apurinic/ deoxyribonucleoside [DNA] linolenoyl-CoA 2 in 16S rRNA oligonucleotide hydroxyglutaryl- GTP 3,20-dione en-3-one K349_RS0113685 F6P F6P dTDP-4-dehydro- GDP-4-dehydro- an N-terminal an N-terminal α-D-galactose a debranched amino acid apyrimidinic site 5'-triphosphate 16S rRNA bifunctional CoA [acp] dideoxy-N-acetyl- β acetyl-CoA C- UDP-α-D-glucose steroid Delta- steroid Delta- 6-deoxy-α-D- 6-deoxy- - L-glutamine L-glutamate 1-phosphate α oligoribonuclease/ DNA methylase: 2-hydroxyglutaryl- 3-hydroxyacyl-ACP glucosamine beta-L-altrosamine mannose-1-phosphate acyltransferase: -limit dextrin (cytosine(1402)-N(4) diguanylate cyclase: isomerase: isomerase: a decanoyl-[acp] glucopyranose L-galactose bifunctional 3-methyl-2-oxobutanoate acyl-CoA PAP phosphatase K349_RS0105585 CoA dehydratase: dehydratase FabZ: 6-phosphate transaminase: guanylyltransferase/ K349_RS0109975 gamma- RNA-directed )-methyltransferase K349_RS0100310 K349_RS0104995 K349_RS0104995 dTDP-4- GDP-L-fucose phosphoribosylaminoimidazolecarboxamide dehydrogenase subunit endonuclease III: thioesterase: NrnA: K349_RS0105550 K349_RS0111465 synthetase: K349_RS0112370 mannose-6- glutamyltransferase: DNA polymerase: RsmH: a 5-methylcytosine [+ 11 isozymes] cholest-4- beta-ketoacyl- UDP-4-amino-4,6- dehydrorhamnose synthase: formyltransferase/IMP VorB: K349_RS0115125 K349_RS0114520 K349_RS0111090 K349_RS0114710 K349_RS0114850 (E)-glutaconyl- progesterone a (2E)-octadec- K349_RS0109150 phosphate isomerase: butanoyl-CoA K349_RS0106760 K349_RS18365 4 in DNA en-3-one ACP synthase II: a 3-oxoacyl-[acp] 3,5-epimerase: K349_RS0111595 a [protein] with α cyclohydrolase: K349_RS0113095 an N - a nucleoside 5'- CoA c-di-GMP dideoxy-N-acetyl- γ -D- 1402 K349_RS0113705 2-enoyl-[acp] glutamine--fructose- K349_RS0104260 an N-terminal 5- -L-glutamyl D-glucopyranose methylcytidine β-L-altrosamine K349_RS0111620 β glutathione glucopyranose di-homo-γ- monophosphate a 3- 6-phosphate D-mannopyranose GDP- -L-fucose oxo-L-proline 5-phosphate α γ CO isobutanoyl-CoA NADH a 3'-terminal a 5'-phospho- in 16S rRNA steroyl-[acp] UDP-4-amino-4, 6- glycogen biosynthesis I (from ADP-D-Glucose) dTDP-4-dehydro- an -( -L-glutamyl) 2 oxododecanoyl- 6-phosphate 1-phosphate leukotriene-D4 unsaturated sugar [DNA] [DNA] linolenate reductase: transaminase dideoxy-N-acetyl- β-L-rhamnose FAICAR a tetrahydrofolate -L-amino acid [acp] K349_RS0113685 (isomerizing): beta-L-altrosamine phosphomannomutase/ D-glucopyranose crotonyl-CoA alpha-D-glucose 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- dTDP-4- K349_RS0113900 N-acetyltransferase: phosphoglucomutase: 6-phosphate dehydrorhamnose phosphate-specific carrier-protein] carrier-protein] β a stearoyl-[acp] D-glucosamine K349_RS0112350 K349_RS0108890 reductase: phosphoglucomutase: ribose phosphorylation 5-formyl- D-glyceraldehyde D-sedoheptulose a single- N-acetyl- - a [release factor]- (R)-methylmalonyl- a (1->4)- reductase: reductase: alpha-D-glucose 5-oxo-L-proline a methanofuran F6P coenzyme A a [protein] Ser/Thr α a dipeptide precorrin-2 NADH beta-ketoacyl- 6-phosphate UDP-2,4-diacetamido- α-D-mannose K349_RS0113340 tetrahydrosarcinapterin 3-phosphate 7-phosphate stranded RNA neuraminate CTP L-glutamine CoA -D-glucan K349_RS0113695 K349_RS0113695 phosphate-specific K349_RS0111615 1,4-alpha-glucan ACP synthase II: 2,4,6-trideoxy-β- 1-phosphate β 5-oxoprolinase: β-D-ribopyranose serine/threonine- peptide chain methylmalonyl- membrane precorrin-2 C(20)- NAD(+)/ a (3R)-3- phosphoglucosamine phosphoglucomutase: dTDP- -L- (S)-3- phosphomannomutase/ branching K349_RS0113705 L-altropyranose K349_RS0103865 acylneuraminate protein kinase: release factor CoA epimerase: dipeptidase: methyltransferase: NADH kinase: hydroxydodecanoyl- a (3R)-3- mutase: mannose-1-phosphate K349_RS0113340 rhamnose hydroxybutanoyl-CoA phosphoglucomutase: D-ribose pyranase: formylmethanofuran-- fructose-6- polyribonucleotide protein GlgB: a 2,3,4-saturated K349_RS0103875 transketolase: CoA pyrophosphatase: cytidylyltransferase: K349_RS17620 N(5)-glutamine K349_RS0109765 K349_RS0104675 K349_RS0102060 K349_RS0112730 [acp] hydroxyacyl-[acyl- K349_RS0113885 guanylyltransferase/ phosphomannomutase/ 3-hydroxyacyl-CoA UDP-glucose-- K349_RS0108890 K349_RS0104355 tetrahydromethanopterin phosphate aldolase: nucleotidyltransferase: K349_RS0107270 stearate fatty acyl-[acp] α UDP-glucose 4- β K349_RS0107715 K349_RS17330 K349_RS0112335 serine kinase: methyltransferase: 3-hydroxyacyl-ACP 3-hydroxyacyl-ACPcarrier protein] -D-glucosamine mannose-6- phosphoglucomutase: dehydrogenase: hexose-1-phosphate -D-ribofuranose N-formyltransferase: K349_RS0111660 K349_RS0112590 (S)-methylmalonyl- a proteinogenic precorrin-3A NADPH UDP-α-D-glucose glu epimerase GalE: K349_RS0112460 K349_RS0113805 a GlgE-glycogen dehydratase FabZ: 1-phosphate 2,4-diacetamido- phosphate isomerase: K349_RS0115345 uridylyltransferase: D-glucopyranose K349_RS0102930 5 CoA amino acid dehydratase FabZ: K349_RS0108890 biosynthesis I K349_RS0109315 a [protein] (L-serine/L- a [release factor]-N K349_RS0111465 2,4,6-trideoxy-β- K349_RS0104260 α 6-phosphate CMP-N-acetyl- K349_RS0111465 UDP-N- -D- K349_RS0109310 D-ribose 5- D-xylulose D-glyceraldehyde a single- threonine) phosphate -methyl-L-glutamine L-altropyranose GDP-α-D- D-glucopyranose acetoacetyl-CoA α-D-glucopyranose dihydroxyacetone 3',5'-ADP 4'-phosphopantetheine a nucleoside β-neuraminate a (2E)-dodec- acetylglucosamine glucopyranose UDP-α-D-galactose phosphate 5-phosphate 3-phosphate stranded RNA mannose 6-phosphate 1-phosphate diphosphate 2-enoyl-[acp] stearoyl-CoA diphosphorylase/ pseudaminic 1-phosphate alpha-D-glucose acetyl-CoA C- D-ribofuranose tetrahydrosarcinapterin a formylmethanofuran glucosamine-1- acid synthase: glucose-1-phosphate dodecanoyl-[acyl- phosphate-specific acyltransferase: alpha-D-glucose phosphate N- K349_RS0112345 adenylyltransferase: ribokinase: carrier-protein] phosphoglucomutase: K349_RS0109975 phosphate-specific K349_RS0104350 acetyltransferase: pseudaminate K349_RS0108730 K349_RS0113340 D-xylulose D-erythrose D-threo-7,8- UDP-4-amino-4-deoxy- an [RNA]-3'- (2S)- reductase: a trans-2- phosphoglucomutase: a formylmethanofuran THMPT D-glucopyranose maltopentaose a ribonucleoside a single 3'-ketolactose β precorrin-8x long chain DHAP NAD + enoyl-[acyl-carrier- K349_RS0113925 a (1->4)- acetyl-CoA D-ribofuranose 5-phosphate 4-phosphate dihydroneopterin -L-arabinopyranose ribonucleoside- ethylmalonyl-CoA K349_RS0113695 a 2,3,4-saturated enoyl-[acyl- ADP-α-D-glucose phosphomannomutase/ K349_RS0113340 triphosphate stranded DNA UDP-4-amino-4, 6- polyphosphate fatty acyl-[acp] protein] reductase: N-acetyl-α-D- α-D-glucan 5-phosphate 2',3'- precorrin-8X methylmalonyl- methylglyoxal NAD(+)/ 2,3,4-saturated fatty carrier protein] phosphoglucomutase: phosphomannomutase/ dideoxy-N-acetyl- cyclophosphate polyphosphate K349_RS0113695 glucosamine glycogen 4-alpha- RNA 2',3'-cyclic methylmutase: CoA epimerase: synthase: NADH kinase: α K349_RS0108890 phosphoglucomutase: formylmethanofuran-- dihydroneopterin beta-glucosidase: beta-L-altrosamine kinase 1: acyl-[acp]:NAD+ 1-phosphate CMP-pseudaminate PRPP biosynthesis synthase GlgA: -D-glucopyranose glucanotransferase: transketolase: DNA primase: K349_RS0101930 K349_RS0109765 K349_RS0110405 K349_RS0112730 K349_RS0108890 tetrahydromethanopterin aldolase: K349_RS0109285 transaminase: phosphodiesterase: K349_RS0106700 oxidoreductase: UDP-N- K349_RS0108725 1-phosphate K349_RS0107265 K349_RS0107715 K349_RS0111815 (2R)- 2,3,4-saturated fatty D-ribose 5- N-formyltransferase: K349_RS17525 K349_RS0112370 an [RNA]-3'-K349_RS0107390 hydrogenobyrinate long chain methylglyoxal NADP + K349_RS0113685 a (1->4)- β acyl-[acp]:NAD+ acetylglucosamine phosphate UDP-α-D-galactose UTP--glucose- D-glucopyranose K349_RS0102930 UDP- -L-threo- ribunucleoside- ethylmalonyl-CoA polyphosphate ribose-phosphate α-D-glucan Alcohol Degradation 3-keto-β-D- oxidoreductase: diphosphorylase/ biosynthesis 1-phosphate 6-phosphate D-glyceraldehyde D-glucopyranose pentapyranos-4-ulose 2'-phosphate a dodecanoyl-[acp] pyrophosphokinase: maltose maltotetraose F6P 6-(hydroxymethyl) glycolaldehyde ssDNA/pppN(pN) galactose K349_RS0113685 glucosamine-1- 1,4-alpha-glucan uridylyltransferase 3-phosphate K349_RS0113930 α (S)-propane-1,2-diol degradation 5-formyl- -7,8-dihydropterin hybrid phosphate N- branching UDP- -D-glucose GalU: glycerol and glycerophosphodiester degradation a methanofuran n -1 PRPP glycerol degradation V tetrahydromethanopterin beta-ketoacyl- acetyltransferase: protein GlgB: UDP-glucose 4- K349_RS0113895 K349_RS0113925 K349_RS0107270 epimerase GalE: (S)-propane- ACP synthase II: UDP-α-D-glucose glycerol K349_RS0109315 1,2-diol glycerol K349_RS0113705 UDP-N-acetyl- a glycogen α (5Z,8Z,11Z,14Z,17Z) α-D-glucopyranose a cytidine 1402 5-α-androstan- a 3β-hydroxy- phosphoenol uridine α UDP-α-D-galactose propanediol/ glycerol UDP-N-acetyl- -D-muramoyl- D-alanyl-D-alanine D-glucopyranose maltohexaose a β-D-galactoside a ribonucleic acid a holo [BryP acyl- laurate fatty acid biosynthesis -D-glucosamine -icosapentaenoyl-CoA CTP 1-phosphate β β δ 5 ethylphosphate glycerol family dehydrogenase: gldA L-alanyl-γ-D-glutamyl-L-lysine in 16S rRNA carrier protein] 3 ,17 -diol -steroid pyruvate initiation (bacteria 16S rRNA steroid Delta- steroid Delta- uridine kinase: a 3-oxotetradecanoyl- dehydratase dihydroxyacetone ACP S- alkaline pyruvate kinase: and plants) 4-alpha- (cytidine(1402)-2'-O) isomerase: isomerase: K349_RS0106320 [acp] medium: pduC a glycerophosphodiester glycerol UDP-N-acetylmuramoyl- beta-glucosidase: acyl-CoA glucose-1-phosphate malonyltransferase: phosphatase: K349_RS0113855 PTS-dependent glucanotransferase: ribonuclease PH: -methyltransferase: K349_RS0104995 K349_RS0104995 3-oxoacyl-[acyl- acetyl-CoA pduD pduE tripeptide--D-alanyl- K349_RS0109285 thioesterase: cytidylyltransferase: K349_RS0113690 K349_RS0105460 UMP dihydroxyacetone K349_RS0107265 K349_RS0109485 a 2'-O- K349_RS0111955 a malonyl- 17-β-hydroxy-5-α- carrier-protein] lauroyl-CoA D- alanine ligase: K349_RS0111090 K349_RS0111565 a 3-oxo-δ 5 -steroid ethanol pyruvate Nucleoside and Nucleotide Biosynthesis 1-propanal glycerophosphodiester glycerol kinase methylcytidine 1402 [BryP acyl- androstan-3-one reductase: K349_RS17405 phosphodiesterase: kinase GlpK: phosphotransferase: in 16S rRNA carrier protein] K349_RS0113695 malonyl-CoA D-galactopyranose a non galactosylated α UMP biosynthesis III K349_RS0101095 K349_RS0107120 K349_RS0107125 maltopentaose maltose (5Z,8Z,11Z,14Z,17Z) a nucleoside a ribonucleic acid CDP- -D-glucose a (3R)-3- superpathway of guanosine pyrimidine deoxyribonucleotides de novo biosynthesis III 5-aminoimidazole propanal UDP-N-acetyl-α-D-muramoyl-L-alanyl- galactose acceptor coenzyme A ACP S- superpathway of adenosine superpathway of pyrimidine K349_RS0107135 -icosapentaenoate diphosphate hydroxytetradecanoyl- nucleotides de novo biosynthesis II ribonucleotide biosynthesis I dehydrogenase: γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine malonyltransferase: nucleotides de novo biosynthesis II nucleobases salvage sn-glycerol [acp] UDP CTP K349_RS0102275 lipid IV biosynthesis (P. putida) K349_RS0113690 gln hydrogencarbonate 3-phosphate DHAP 3-hydroxyacyl-ACP A uracil propan-1-ol vitamin B12-dependent PRPP glycerol degradation II a plant soluble p-nitrophenyl- a glucosylated dehydratase FabZ: IMP uracil + IMP ribonucleotide amidophosphoribosyltransferase: D-glucopyranose maltotriose a glucan β FMN NAD(P)H H a formylmethanofuran a holo [PedD acyl- a holo [BryU acyl- reduced riboflavin 5-aminolevulinate (R)-glycerate a (3R)-3- a malonyl-[acp] asp CDP phosphoribosyltransferase: propanoyl-CoA asp heteroglycan -D-galactoside glycogenin K349_RS0111465 reductase: K349_RS0113110 CAIR carrier protein] carrier protein] 1,4-alpha-glucan hydroxydecanoyl- UDP-N-acetyl- glutamine- β formylmethanofuran porphobilinogen D-glycerate K349_RS0104825 5-phospho- - K349_RS0114230 glycerol ACP S- ACP S- a (2E)-tetradec- [acp] α-D-glucosamine ketoacyl-ACP hydrolyzing IMP dehydrogenase: vitamin B12-dependent phosphate glycerol 4-alpha- 4-alpha- dehydrogenase: flavin reductase: synthase: branching dehydrogenase: adenylosuccinate dUDP D-ribosylamine bifunctional pyr operon DHAP beta-glucosidase: malonyltransferase: malonyltransferase: 2-enoyl-[acp] synthase III: carbamoyl- K349_RS0114890 ribonucleotide propanoyltransferase: dehydrogenase: glucanotransferase: glucanotransferase: flavin reductase: K349_RS0102895 K349_RS0107330 K349_RS0102100 protein GlgB: K349_RS16595 synthase: phosphoribosylamine- transcriptional regulator/uracil phosphoribosylaminoimidazolesuccinocarboxamide K349_RS0109285 K349_RS0113690 K349_RS0113690 myristoyl-[acyl- acyl-ACP--UDP-N- K349_RS0113680 phosphate synthase: reductase: K349_RS0102245 gldA K349_RS0107265 K349_RS0107265 K349_RS0107330 K349_RS0102900 K349_RS0107270 acetylglucosamine K349_RS0110840 K349_RS0104825 -glycine ligase: phosphoribosyltransferase synthase: K349_RS0113130 a malonyl- a malonyl- riboflavin porphobilinogen hydroxypyruvate carrier-protein] K349_RS0101760 propanoyl dihydroxyacetone K349_RS0102935 a glycogen O-acyltransferase: an acetoacetyl-[acp] XMP K349_RS0113090 PyrR: K349_RS0105375 [PedD acyl- [BryU acyl- reductase: K349_RS0101765 dUTP dCDP phosphate a methanofuran K349_RS0111470 UMP a plant soluble D-galactopyranose carrier protein] carrier protein] K349_RS0113695 adenylo-succinate GAR maltose a glucan D-glucopyranose 4-nitrophenol FMNH NAD(P) + glutamine- heteroglycan 2 dUTP diphosphatase: (d)CMP kinase: acetate kinase: SAICAR 2,3,4-saturated fatty carbamoyl asp hydrolyzing UDP-3-O-[(3R)-3- adenylosuccinate K349_RS17220 phosphoribosylglycinamide K349_RS0113570 K349_RS0113655 acyl-[acp]:NAD+ hydroxydecanoyl]- phosphate GMP synthase: superpathway of pyrimidine deoxyribonucleoside salvage DHAP lyase: nucleoside triphosphate dCTP formyltransferase: UMP kinase: oxidoreductase: N-acetyl-α-D- K349_RS0111795 K349_RS0114490 pyrophosphohydrolase: 2'-deoxycytidine K349_RS0113100 K349_RS0115535 propanoate a [histone]-N 6 - XLLG xyloglucan a long-linear 5-guanidino-2- N-acetyl-L- K349_RS0113685 glucosamine aspartate NAD + D-glucopyranose a maltodextrin α-D-glucopyranose α NADP + FMNH a holo [PedN acyl- dimethylarsonite a 3-oxo-δ 5 -steroid prephenate (R)-glycerate K349_RS0113955 acetyl-L-lysine oligosaccharide -D-glucan 2 oxopentanoate glutamate 5- UDP-3-O-[3- phosphatidylserine and carbamoyltransferase GMP FGAR UDP carrier protein] 2'-deoxycytidine 5-guanidino-2- semialdehyde arsenite steroid Delta- prephenate D-glycerate a myristoyl-[acp] hydroxymyristoyl] N- phosphatidylethanolamine catalytic subunit: AMP dUMP cytidine deaminase: ACP S- N-acetyl-gamma- kinase: 4-alpha- 4-alpha- oxopentanoate methyltransferase: isomerase: dehydratase: dehydrogenase: acetylglucosamine biosynthesis I K349_RS0105380 FAD-dependent K349_RS0107245 phosphoribosylformylglycinamidine NAD-dependent beta-glucosidase: malonyltransferase: glutamyl-phosphate guanylate kinase: K349_RS0114315 glucanotransferase: glucanotransferase: flavin reductase: decarboxylase: K349_RS0101670 K349_RS0104995 K349_RS0103700 K349_RS16595 beta-ketoacyl- deacetylase: thymidylate synthase: [+ 3 isozymes] synthase: K349_RS0113115 deacylase: K349_RS0109285 K349_RS0113690 reductase: a CDP-diacylglycerol K349_RS0113595 adenylate kinase: K349_RS0113120 K349_RS0113125 UTP K349_RS0107265 K349_RS0107265 K349_RS0107330 K349_RS0108940 a malonyl[PedN K349_RS0102980 a 3-oxo- 3-phenyl-2- ACP synthase II: K349_RS0111460 CDP-diacylglycerol--serine K349_RS0113790 K349_RS0113050 trimethylarsine hydroxypyruvate N-carbamoyl- K349_RS0112135 4-guanidinobutyraldehyde N-acetylglutamyl- ∆ 4 K349_RS0113705 UDP-3-O-(3- 2'-deoxyuridine dCMP CTP synthase: acyl-carrier -steroid oxopropanoate O-phosphatidyltransferase: L-aspartate dTMP FGAM XXXG xyloglucan phosphate hydroxydecanoyl) (d)CMP kinase: K349_RS0111680 a short 1,4- protein] a 3-oxohexadecanoyl- K349_RS0109835 GDP 2''-O-acetyl- a maltodextrin maltose D-galactopyranose + α deoxynucleoside a [histone]-L-lysine nicotinamide oligosaccharide α-D-glucan FMN NADPH H [acp] - -D-glucosamine a 3-sn-phosphatidyl-L-serine dihydroorotase: ADP dTMP kinase: K349_RS0113570 phosphoribosylformylglycinamidine CTP guanine and ADP-ribose UDP-3-O-(3- K349_RS0114455 kinase: K349_RS0105385 dCDP cyclo-ligase: K349_RS0113105 guanosine salvage 3-oxoacyl-[acyl- hydroxymyristoyl) phosphatidylserine K349_RS0114315 thymidine carrier-protein] GDP kinase: vitamin B12- vitamin B12- vitamin B12- vitamin B12- dTDP glucosamine N- decarboxylase family (S)-dihydroorotate AIR a [protein]-N 6 - XLXG xyloglucan an [amino group carrier protein]- (2R)-phospho- D-arabinofuranose a negatively 3-oxo-24-ethyl- K349_RS0112135 dependent dependent dependent dependent + D-glucopyranose maltotetraose + reductase: acyltransferase: protein: K349_RS0109840 dUMP guanosine NAD oligosaccharide C-terminal-γ-(L-glutamate 5- FMN NADH H an adenine in DNA methylarsonite oxaloacetate ribonucleotide ribonucleotide ribonucleotide ribonucleotide deoxynucleoside acetyl-L-lysine 3-sulfolactate 5-phosphate supercoiled DNA cholest-5-ene K349_RS0113695 K349_RS0111455 dihydroorotate ATP pyrimidine/purine semialdehyde-2-yl)-L-glutamate type I restriction- 3-deoxy-8- reductase: reductase: reductase: reductase: kinase: dCTP adenine salvage N-acetyl-gamma- 2-phosphosulfolactate arsenite type I DNA steroid Delta- oxaloacetate a (3R)-3- UDP-2-N-[(3R)-3- an L-1-phosphatidylethanolamine dehydrogenase: dTTP nucleoside phosphorylase: modification phosphooctulonate K349_RS0104825 K349_RS0104825 K349_RS0104825 K349_RS0104825 K349_RS0114315 NAD-dependent 4-alpha- glutamyl-phosphate phosphatase: methyltransferase: topoisomerase: isomerase: decarboxylase: hydroxyhexadecanoyl- hydroxydodecanoyl]- K349_RS0105395 GTP K349_RS0101215 beta-glucosidase: flavin reductase: system subunit M: synthase: deacylase: glucanotransferase: reductase: K349_RS0108750 K349_RS0101670 K349_RS0111155 K349_RS0104995 K349_RS0101900 [acp] 3-O-[(3R)-3- PRPP anaerobic K349_RS0109285 K349_RS0107330 K349_RS0106445 K349_RS0111515 3-hydroxyacyl-ACP orotate adenine purine-nucleoside K349_RS0107265 an [amino group carrierK349_RS0102980 protein]- 6 3-oxo-24-ethyl- dADP ribonucleoside- K349_RS0113050 (2R)-3-sulfolactate an N -methyladenine dimethylarsonite a relaxed DNA pyruvate dehydratase FabZ: hydroxydecanoyl]- phosphorylase: C-terminal-γ-(5-phospho- KDO-8P cholest-4-ene α anaerobic dGDP triphosphate in DNA K349_RS0111465 -D-glucosamine orotate xanthine and K349_RS0115100 XXXG xyloglucan L-glutamyl)-L-glutamate ribonucleoside- reductase: dTMP 2''-O-acetyl- D-galactopyranose + UDP-2,3- phosphoribosyltransferase: xanthosine salvage guanine nicotinamide a [protein]-L-lysine maltose maltotriose oligosaccharide FMNH NAD a (2E)-hexadec- triphosphate adenine deaminase: ADP-ribose 2 diacylglucosamine K349_RS0105405 K349_RS0108060 dTMP kinase: 2-enoyl-[acp] reductase: K349_RS0100145 diphosphatase: K349_RS0114455 xanthine palmitoyl-[acyl- K349_RS0101015 K349_RS0108060 xanthosine phosphoribosyltransferase: orotidine 5'- dTDP 3-methyl-2- 5,10-methylene- XXLG xyloglucan (S)-2,3,4,5- a 3,5,7,9,11,13,15- 3-phospho- a 2'- (3Z)-hex- carrier-protein] dATP pyrimidine/purine AMP K349_RS0109970 porphobilinogen an aldehyde (S)-malate (S)-NADPHX lipid X (P. putida) phosphate purine deoxyribonucleosides salvage hypoxanthine oxobutanoate tetrahydromethanopterin IMP oligosaccharide tetrahydrodipicolinate hepta-oxo- (R)-glycerate deoxyribonucleoside 3-en-1-ol reductase: nucleoside phosphorylase: hypoxanthine 4-hydroxy- hexadecanoyl-[PKS-acp] dGTP hydroxymethylbilane phosphoglycerate deoxynucleoside aldehyde ferredoxin CHAT domain- NAD(P)H-hydrate K349_RS0113685 hypothetical protein: orotidine-5'- K349_RS0101215 phosphoribosyltransferase: bifunctional tetrahydrodipicolinate fumarate hydratase: guanine and xanthine 3-methyl-2-oxobutanoate aldo/keto reductase: synthase: dehydrogenase: kinase: oxidoreductase: containing protein: dehydratase: K349_RS0111490 phosphate purine-nucleoside dTTP K349_RS0112850 phosphoribosylaminoimidazolecarboxamide beta-glucosidase: reductase: K349_RS0109710 a palmitoyl-[acp] decarboxylase: 2'-deoxyguanosine 2'-deoxyadenosine guanosine salvage II phosphoribosyltransferase: hydroxymethyltransferase: K349_RS0109285 K349_RS0102455 K349_RS18450 K349_RS0107540 K349_RS0114315 K349_RS0115630 K349_RS0101855 K349_RS0112905 lipid A deoxynucleoside deoxynucleoside phosphorylase: K349_RS0109970 K349_RS0104000 formyltransferase/IMP K349_RS0113075 9-hydroxy-3,5,7,11,13,15- a 2'- (3Z)-hex-3- K349_RS0105400 K349_RS0115100 GMP cyclohydrolase: K349_RS0113095 (2S,4S)-4-hydroxy-2,3,4,5- preuroporphyrinogen 3-phosphooxypyruvate deoxyribonucleoside a carboxylate fumarate NADPH disaccharide kinase: kinase: xanthine hypoxanthine tetrahydrodipicolinate hexaoxohexadecanoyl- en-1-yl acetate UMP FAICAR XXXG xyloglucan 5'-monophosphate (P. putida) K349_RS0114315 K349_RS0114315 guanosine phosphoribosyltransferase: D-galactopyranose [PKS-acp] tetraacyldisaccharide dGMP dAMP xanthine pyrimidine K349_RS0112850 2-dehydropantoate THMPT oligosaccharide palmitate 4'-kinase: phosphoribosyltransferase: ribonucleosides salvage I K349_RS0111505 K349_RS0109970 IMP lipid IV guanine cytidine β α A 2,5-diamino-6-(5- a -Gal-(1->3)- -Gal-(1->2) 1518 D-ribulose phosphatidylglycerolphosphate 1915 adenine / β (2R,3S)-3- (P. putida) a pseudouridine in 23S rRNA α uroporphyrinogen-III citrate NaMN -D-allopyranose precorrin-4 CMP XMP phospho-D-ribitylamino) -[ -(1->6)-oligomannan] adenine 1519 in 16S rRNA isopropylmalate 5-phosphate xanthine cytidine deaminase: (1-oleoyl, 2-palmitoyl) polysaccharide phosphorylation pyrimidin-4(3H)-one 23S rRNA ribosomal RNA uroporphyrinogen-III bifunctional 3-isopropylmalate ribulose-phosphate precorrin-4 C(11)- dGDP dADP phosphoribosyltransferase: K349_RS0107245 bifunctional pyruvyl aconitate hydratase: D-ribose pyranase: palmitoyl-CoA phosphatidylglycerophosphatase (pseudouridine(1915)- small subunit C-methyltransferase: metallophosphatase/ dehydratase: leuD 3-epimerase: methyltransferase: CMP K349_RS0109970 [+ 3 isozymes] CMP diaminohydroxyphosphoribosylaminopyrimidine transferase CsaB: K349_RS0101710 K349_RS0104355 deaminase/5-amino-6-(5-phosphoribosylamino) A: K349_RS0107400 N(3))-methyltransferase methyltransferase K349_RS0102080 5'-nucleotidase: [+ 3 isozymes] K349_RS0107415 K349_RS0102045 (d)CMP kinase: hypoxanthine K349_RS17080 RlmH: K349_RS0114915 6 A: K349_RS01136251518 K349_RS0102450 D-xylulose K349_RS0113570 uridine uracil reductase RibD: K349_RS0115000 1-oleoyl-2-palmitoyl- 3 1915 a 4,6-CH (COO-)C-β-Gal-(1->3)-α- N -dimethyladenine β β-D-allofuranose (2S)-2- phosphoribosyltransferase: 5-amino-6-(5-phospho- an N -methylpseudouridine 3 precorrin-2 D-threo-isocitrate -D- precorrin-5 CDP α /N 6 -dimethyladenine 1519 isopropylmalate 5-phosphate K349_RS0112850 phosphatidylglycerol in 23S rRNA Gal-(1->2)-[ -(1->6)-oligomannan] ribosylnicotinate uridine kinase: D-ribitylamino)uracil in 16S rRNA K349_RS0106320 dGTP dATP GMP UMP UDP-N-acetyl- CTP 5,10-methenyl- a single a double α pregn-5-ene- CDP-α-D-glucose β 2'-deoxycytidine 5,10-methenyltetrahydromethanopterin α-D-glucosamine a uridine in tRNA an -limit dextrin GDP- -L-fucose campesterol tetrahydrosarcinapterin stranded DNA stranded DNA 3,20-dione-17-ol CDP-glucose 4,6- deoxynucleoside UDP-N-acetylglucosamine DNA/RNA tRNA-dihydrouridine 4-alpha- steroid Delta- GDP-L-fucose steroid Delta- methenyltetrahydromethanopterin methenyltetrahydromethanopterin 1-carboxyvinyltransferase: deoxyribonuclease dehydratase: kinase: nuclease SfsA: synthase: glucanotransferase: isomerase: K349_RS0111570 synthase: K349_RS0114315 isomerase: cyclohydrolase: K349_RS0102940 cyclohydrolase: K349_RS0102940 K349_RS0114245 IV: K349_RS0113865 K349_RS0113350 K349_RS0107645 K349_RS0107265 K349_RS0104995 K349_RS0111595 K349_RS0104995 UDP-N-acetyl-α-D- α CDP-4-dehydro-6- dCMP a -limit dextrin α α GDP-4-dehydro- 5-formyl- 5-formyl- glucosamine-enolpyruvate a 5,6-dihydrouridine 17- - deoxy- -D-glucose campest- a 5'-phosphooligonucleotide a 5'-phosphooligonucleotide with short branches α-D-rhamnose β a branched- tetrahydromethanopterin tetrahydrosarcinapterin in tRNA hydroxyprogesterone 4-en-3 -ol chain amino acid a sugar 6- phosphate D-glucose 6- a C4- an aliphatic a basic a basic a sugar 6- phosphonate galactitol 1- a nucleotide queuosine molybdate a tricarboxylate a dipeptide phosphate dicarboxylate sulfonate amino acid amino acid phosphate phosphite phosphate chromate predicted a lipopolysaccharide ABC predicted transporter PEP-driven RS16780 RS0105725 RS0106455 RS0106850 RS0104185 RS0101565 RS0112425 RS0105195 RS0113060 of a RS0100860 RS0110145 RS0100685 RS0111755 RS0101740 RS0100890 transporter branched- of a sugar chain a nucleotide D-glucose queuosine a C4- an aliphatic a basic a basic a sugar amino acid phosphonate molybdate galactitol a tricarboxylate a dipeptide chromate dicarboxylate sulfonate amino acid amino acid phosphite a lipopolysaccharide a sugar a branched- chain amino acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.