Ling Zhi Lung Formula Ling Zhi Fei Pian

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Origins: Modern formula Ling Zhi Lung Formula Ling Zhi Fei Pian

Ling Zhi Lung Formula (Ling Zhi Fei Pian) is a modern formulation based on research in China and the US. General Signs/Symptoms Asthma, wheezing, labored breathing (often worse with exertion), cough. Actions 1. Drains phlegm and fluid from the lungs 4. Invigorates qi and blood circulation through the skin 2. Rectifies lung qi, stops wheezing, and settles cough 5. Calms shen 3. Strengthens lung qi, nourishes blood

Ingredients Pinyin Latin English Percent of Formula Ling Zhi (chief) Ganoderma Reishi 46% Ku Shen (deputy) Sophorae Flavescentis Radix Shrubby Sophora Root 21% Ting Li Zi (deputy) Lepidii Semen/Lepidium Semen Lepidium Seed 13% Hong Zao, Da Zao (assistant) Jujubae Fructus Jujube Fruit, Chinese Red Date 13% Gan Cao (assistant) Glycyrrhizae Radix Chinese Licorice Root 7% General Indications / Modern Applications • Abscess, lung • Dyspnea • Skin disease (deficiency-type) • Allergies • Eczema • Wheezing • Asthma • Influenza, post-illness with • Breathing, labored with exertion damage to qi • Cough • Scleroderma

Formula Discussion Ling Zhi Lung Formula (Ling Zhi Fei Pian) is a modern combination of a classic formula from Zhang Zhong-Ji’s book, Essential Prescriptions of the Golden Cabinet ( Jin Gui Yao Lue) plus a formula developed in modern research.i Zhang’s formula consisted of two ingredients, lepidium seed (ting li zi) and jujube date (da zao), which combine to aggressively drain phlegm and fluid from the lungs without injuring them. Lepidium and Jujube Decoction to Drain the Lung (Ting Li Da Zao Xie Fei Tang) was frequently prescribed by Zhang to treat lung abscess or wheezing/panting due to an invasion into the lungs by water rheum or phlegm rheum. The inclusion of this two-ingredient classic formula in Ling Zhi Lung Formula (Ling Zhi Fei Pian) boosts its power to drain the lungs of the excess fluids associated with asthmatic breathing. The modern formula serving as the base ofLing Zhi Lung Formula (Ling Zhi Fei Pian) consists of three ingredients, which have been demonstrated to be nearly as effective as prednisone for treating asthma, without the associated side-effects.ii In brief, Ling Zhi Lung Formula (Ling Zhi Fei Pian) is all about treating asthma, but because this goal involves a great deal more than simply “arresting wheezing,” the formula’s various actions combine to treat several non-asthmatic conditions. For instance, asthma (or just restricted lung qi) can lower blood-oxygen levels, therefore the shen is frequently affected by trapped lung qi:Ling Zhi Lung Formula (Ling Zhi Fei Pian) has a strong action to benefit the shen. Free- coursing lung qi is also important for the maintenance of healthy skin; by draining the pathogens that limit the coursing of lung qi and by nourishing the blood, Ling Zhi Lung Formula (Ling Zhi Fei Pian) can help certain skin conditions like eczema and scleroderma.iii Ling Zhi Lung Formula (Ling Zhi Fei Pian) is an effective substitute for Minor Bluegreen Dragon Decoction(Xiao Qing Long Tang), which is no longer available in the United States due to the inclusion of two banned substances: ephedra (ma huang) and asarum (xi xin). Traditionally, Xiao Qing Long Tang was used to treat wind-cold with fluid accumu- lation in the lungs. In modern times, this formula has become a staple for treating asthma and wheezing due to phlegm- cold in the lungs by warming the interior and transforming fluids. One of the problems facing Chinese herbalists in the

Ling Zhi Lung Formula Monograph © September 2015, Herbal Medicine Press Ling Zhi Lung Formula 2 take each, 2tablets of 3 times aday. For chronic asthma/ asthmatic cough, Wan) Shou Immortals Formula Lung Formula the case, take L 3-4tablets of severe deficiency. yin When is this drying when there moderate is to Ling Zhi Lung Formula With underlying deficiency: yin asthma and restore lung function. months to correct some of cases As acorrective: 3 weeks). 2-3 times day, per until resolved to (up condition, take 3-5tablets needed, as a thedevelopingasthmatic first of signs chronic or conditions: Sub-acute to appropriate professional. medical hours, re-evaluate the or diagnosis refer noticeably improve withinthe first 24 by 50%or more. condition If not does times daily after symptoms have abated 24 hours. Reduce frequency to three tablets needed, as up to fivein doses Acute conditions: D below for how to compensate for this.) overly drying. (See “Dosage” section Formula deficiencyis presenting, yin significant If to pneumonia. lung fire, the wheezing or if is due conditionDo not if due use is to C rightthe tight be will Often or slippery pulse in May superficial be with asthma.acute P Normal or thick coating. T F ormul ongue ulse ontraindications osage • Calms • Invigorates qiandblood • Strengthens lungqiandnourishes lungqi,stops wheezing,• Rectifies • Drains phlegm andfluidfrom circulation through theskin blood settles cough lungs

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v (Ling Zhi Fei Pian) Zhi Fei (Ling ) is an effective vasodilator vasodilator ) is effective an 2 (ting zi) li which constitutes the second part part second the constitutes which to treat superficial edema and nasaland edema superficial treat to , sophora root root sophora , (PGI 2 . production while not increasing PGE α 2 2 Ta n g , when not mitigated by red jujube date jujube red by mitigated not when , protective this formulation, present the In . . This base formula is used to treat allergic treat to is used formula Thisbase . (ling zhi) lepidium seed , PGF 2 and the chief herb. (ting zi) li (tingzi) li (gan cao) , can be harshly drying, especially for the mucosa in mucosa the for especially drying, be harshly can , Prostaglandin I Prostaglandin Contracted airway smooth muscle constricts the air the constricts muscle smooth airway Contracted Asthma attacks occur when Th2 (type-2 helper T Th2 (type-2 when occur helper attacks Asthma lergic inflammation. Research shows that these herbs herbs these that shows Research inflammation. lergic PGIincrease TXA and has anti-inflammatory effects that can inhibit al can inhibit that effects has and anti-inflammatory way during an asthma attack. This base formula re formula Thisbase attack. asthma an during way contractility. muscle smooth airway duces herbs used in this study were shown to suppress Th2 suppress to shown were used study in this herbs activity. cells, a white blood cell subset) secrete cytokines that that cytokines secrete subset) cell blood a white cells, The wheezing. causing lungs, the irritate and inflame noted in the airways, and a reduction of in airway a reduction and airways, in the noted wasobserved. flammation sure time index levels were essentially the same as same in the essentially were levels index time sure lavage in broncho-alveolar Eosinophils mice. normal cells were goblet Few lower. significantly were fluid and reduction of airway inflammation. Airway pres Airway of inflammation. airway reduction and phase airway reaction. These herbs also significantly also significantly herbs These reaction. phase airway lev IgE and C4 levels, leukotriene histamine, reduced of severity the asthma. reduce all of help which els, mained normal or slightly higher in ovalbumin sen in ovalbumin higher slightly or normal mained indicating no bronchoconstrictionsitized and mice, early- abolished treatment the that demonstrating Ling Zhi Lung Formula Lung Zhi Ling • • • •This formula also reduced late-phase airway reaction reaction airway late-phase reduced also formula •This •The research showed the peak expiratory flow re flow expiratory peak the showed research •The of herbs: two Lepidium and Jujube Decoction to Drain the Lungs ( Lungs the Drain to Decoction Jujube and Lepidium Tang), Fei Zao Da Xie Li with no adverse side effects. side adverse no with ganoderma ganoderma root in mice prednisone rival to has and been shown asthma Research studies have been done on ovalbumin sensitized sensitized ovalbumin on been done have studies Research seen in those to similar are characteristics (whose mice ingredients: three using allergic asthma) with humans (gan cao) Applications Modern cient to protect the lungs from the effects of lepidium effects the the from lungs the protect to cient seed root of actions licorice the both by quality is supported seed zao) date jujube red the But face. the Da Zao Xie Fei Fei ZaoDa Xie withcongestion Theactions clear discharge. of lepidium from the lungs. Less frequently, he recommended recommended he Less frequently, lungs. the from Ling Zhi Lung Formula 4 vi vi v iv iii ii i Endnotes are some combinations that may useful. be Ling Zhi Lung Formula are In used. (su zi) Decoction for Directing Downward Qi function to stop wheezing and cough. In Both formulas have multiple herbs with the primary what by their strategies for accomplishing their results. the herbs chosen to perform these functions, and some wheezing, and stop cough.differ They dramatically by formulas have similar actions to descend lung qi, arrest with thin watery sputum and shortness breath. of Both FeiZhi Pian) Tengfei Zhang, al., et and Immunological“Pharmacology aHerbalActions of Medicine ASHMI on Allergic Asthma”, Li XM,Li Huang al., CKet Chinese herbal“The medicine formulaMSSM-002 Supppresses Allergic Airway Hyperactivity and Modulates Research TH1/TH2 Responses aMurine in Model Allergic of Asthma,” Hoang BX, Shaw DG, al., et “New Approach in Asthma Treatment Using Excitatory Modulator” Robert Ronald, al., et Da Li Zao Xie“Ting Fei Tang Treats Children with of Asthma”, 64Cases Li, ibid. Cheng, X-R, , damaging yin cough, orinanacute febrile conditiondry that is mouthand deficient signs andsymptoms likedry For wheezingandcough whenpresented withyin or irregular pulse For asthmaaccompanied withexcessive saliva watery For pattern chronic asthmawithaqiandyindeficiency tion dueto water metabolismdysfunction For wheezingaccompanied withexcessive water reten at invasion) thefirstsigns ofthe external For asthmatriggered by aviral invasion (mosteffective For acute asthmawithyindeficient constitution licorice root , Vol 24, 2010. Journal ofClinical Dermatology Ling Zhi Lung Formula are both for used wheezing (gan cao) (gan

(Ling Fei Zhi Pian) , and peucedanum , Vol. 16, p. 122, 1987and Lie, C.R., ganoderma , seed perilla Perilla Seed and coughand is usually used by itself to treat usually is by used itself asthmatic breathing and cough, but there (qian hu) (qian U (ling (ling seful Journal of Allergy and Clinical Immunology Clinical and Allergy Journal of - -

C ombinations strengthens the lungs and drains the phlegm-fluids out. and descending phlegm, while ing Downward Qi draining/clearing. differsin that its actions are partly supportive and partly po) (huo nellia ( Fruit Decoction for Directing Downward Qi two formulas differin how they transform fluids. seed lepidium zhi) Combine with Combine with Combine with Combine with Combine with Combine with , sophora root ban xia) Journal ofClinical Dermatology is used to used damp. is dry Viola Clear Fire Formula Formula Eight Immortals Poria 5Formula. Sheng Formula Mai Lily Preserve Formula. Metal Baked Licorice Formula. (ting li zi)(ting to transform phlegm and magnolia bark Perilla Fruit Decoction for Direct resolves phlegm by drying, dislodging (ku shen) (ku State Medical Forum Phytotherapy ResearchPhytotherapy are for used this function. These , licorice root , Oct, 2000. Ling Zhi Lung Formula Ling Zhi Lung Formula . , Vol. 15, p. 128, 1986. . , May 1994. . Phytotherapy Phytotherapy , Vol. 21, 2007. (gan cao) (gan uses pi uses Perilla , and , and - -