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THE DEADLIEST IN

Global Pandemics by Toll

Worldwide 1877 - 1977** 500,000,000 1918 - 1919 50,000,000 of Justinian 483 - 565 30,000,000 - 50,000,000 HIV/AIDS 1981 - Present 32,000,000+ so far / 1347 - 1351 25,000,000 Cocoliztli 1545 - 1547 5,000,000 - 15,000,000 Smallpox Epidemic *The Great Plagues consisted of 1519 - 1520** 5,000,000 - 8,000,000 around 40 resurgences of the bubonic plague, primarily in . 5,000,000 165 - 180 was 3,798,000 - 4,798,000 invented during the 1817 - 1975*** Black Plague. Sailors The Great Plagues 3,000,000 would not leave their 1348 - 1665* ships for 40 days to avoid Smallpox Epidemic spreading the illness; the 1918 - 1922 2,500,000 **Smallpox is most often associated with word comes from the the , when it decimated the Japanese Smallpox Epidemic 2,000,000 Italian word for 40, native population of Mexico. However, it 735 - 737** “quaranta.” resulted in the most casualties during the COVID-19 last 100 years of its existence. Between 2019 - Present 1,080,000+ as of 10/14/2020 1877 and 1977, smallpox was responsible for the deaths of an estimated Flu 500,000,000 people. 1968 - 1970 1,000,000 Smallpox Epidemic 1870 - 1875** 500,000 Japanese Smallpox Epidemic 735 - 737 Swine Flu 2,000,000 2009 - 2010 151,700 - 575,400 5,000,000 Yellow Mexico Smallpox Epidemic 1800 - 1802 100,000 - 150,000 1519 - 1520 5,000,000 - 8,000,000

Chile Smallpox Epidemic 1561 - 1562 Unknown

A Timeline of the Massachusetts Smallpox Epidemic 200 1633 - 1634 Deadliest Pandemics 1,000

in History 30,000,000 - Boston Smallpox Epidemic 50,000,000 1677 - 1678 1,000 Antonine 165 - 180 Plague 300 St. Lawrence Valley Smallpox Epidemic 1702 - 1703 Plague 483 - 565 of Justinian 1,300

Iceland Smallpox Epidemic 1707 - 1709 18,000+ 400 Japanese 1721 Boston Smallpox Outbreak Smallpox 735 - 737** 2,000,000 1721 - 1722 Epidemic 844

New Smallpox Epidemic 1733 500 Unknown

North Carolina Smallpox Epidemic Bubonic 1738 - 1739 Plague / 1347 - 1351 25,000,000 7,700 - 11,700 Black Death Charleston Smallpox Epidemic 600 1760 730 - 940

Pittsburgh Area Smallpox Outbreak 1763 Unknown The Great 1348 - 1665* Plagues 700 3,000,000 North American Smallpox Epidemic 1775 - 1782 11,000+

Pueblo Indians Smallpox Epidemic 1788 Mexico 5,000,000 - Unknown Smallpox 1519 - 1520** 800 8,000,000 Epidemic First New South Wales Smallpox Epidemic 1789 - 1790 Unknown

Second New South Wales Smallpox Epidemic 1828 - 1829 900 19,000 5,000,000 - Smallpox Epidemic Cocoliztli 1545 - 1547 15,000,000 1831 - 1834 Unknown

Great Plains Smallpox Epidemic 1000 1837 - 1838 17,000+ 1800 - 1802 100,000 - 150,000 South Smallpox Epidemic 1840 Unknown 3,798,000 - Cholera 1817 - 1975*** Victoria Smallpox Epidemic 1100 4,798,000 1857 Unknown Europe Smallpox 1870 - 1875** 500,000 British Columbia Smallpox Epidemic Epidemic 1862 - 1863 32,000

1200 Europe Smallpox Epidemic Worldwide Smallpox 1877 - 1977** 500,000,000 1870 - 1875 Epidemic 500,000 Worldwide Smallpox Epidemic 1877 - 1977 500,000,000 1300

The was responsible for: 1400 of Justinian Spanish Flu 1918 - 1919 50,000,000 The Bubonic Plague

The Great Plagues

1500

Cholera

***Like smallpox and the Bubonic Plague, cholera also struck in waves. Russia 1600 There were seven major pandemics Typhus 1918 - 1922 2,500,000 between 1817 and 1975. Epidemic

First Hong Kong 1968 - 1970 1,000,000 Flu 1817 - 1824 1,000,000 - 2,000,000 1700 Second Pandemic 1829 - 1837 100,000

Third Pandemic 1846 - 1860 HIV/AIDS 1981 - Present 1800 32,000,000+ 1,000,000+ so far Fourth Pandemic 1863 - 1875 600,000+

Fifth Pandemic 1900 1881 - 1896 298,600

151,700 - Sixth Pandemic Swine Flu 2009 - 2010 1899 - 1923 575,400 800,000+

2000 Seventh Pandemic COVID-19 2019 - Present 1,080,000+ 1961 - 1975 as of 10/14/2020 Unknown

Resources: www.history.com/news/pandemics-end-plague-cholera-black-death-smallpox www.businessinsider.com/pandemics-that-changed-the-course-of--history--flu-aids-plague#smallpox-15th-17th-centuries-3 www.news..co.uk/2/hi//4381924.stm www.en.wikipedia.org/wiki/List_of_epidemics www.en.wikipedia.org/wiki/Template:COVID-19_pandemic_data