Geom Geom Ratio of mean mean Parametric p- geom FDR of of Symbol Name value means intensit intensi ID Pla/Bag ies in ties in dapper, antagonist of beta-catenin, homolog 1 (Xenopus 29 1,69E-05 0,0302321 72,8 7,6 9,579 DACT1 laevis) heparan sulfate (glucosamine) 3-O- sulfotransferas 797 0,0011054 0,0757259 237,2 25,7 9,23 HS3ST2 e 2 growth differentiation 874 0,0012657 0,0791194 204,9 23,6 8,682 GDF15 factor 15 potassium voltage-gated channel, Isk- related family, 1756 0,0038928 0,1210936 283,5 37,7 7,52 KCNE1 member 1 membrane- spanning 4- domains, subfamily A, 7305 0,0471766 0,3530226 150,7 20,9 7,211 MS4A1 member 1 POU domain, class 2, associating 5060 0,0248103 0,2680447 58,3 8,6 6,779 POU2AF1 factor 1 442 0,0004744 0,0586829 27,3 4,2 6,5 TSPAN12 tetraspanin 12 44 2,60E-05 0,0312927 57,2 9 6,356 ASTN2 astrotactin 2 266 0,0002545 0,0521767 138,9 21,9 6,342 PRR6 proline rich 6 1218 0,0021841 0,097918 152,7 25,4 6,012 MCOLN3 mucolipin 3

FERM domain 173 0,000154 0,0481428 110 18,7 5,882 FRMD4A containing 4A male sterility domain 4469 0,0199658 0,2442435 1200,3 210,6 5,699 MLSTD1 containing 1 aldehyde dehydrogenas e 1 family, 3738 0,0142747 0,2087933 1816,5 320,1 5,675 ALDH1A2 member A2 deoxyribonucle 779 0,0010754 0,0753005 268 48,3 5,549 DNASE1L3 ase I-like 3

TSC22 domain family, member 944 0,0014302 0,0826707 872,3 158,2 5,514 TSC22D1 1 Male sterility domain 6858 0,0422377 0,3367178 631,6 116,2 5,435 MLSTD1 containing 1 patatin-like phospholipase domain 7 6,60E-06 0,0302321 58,1 10,7 5,43 PNPLA3 containing 3 hypothetical protein 1857 0,0042809 0,126041 52,6 9,8 5,367 FLJ36748 FLJ36748

Fatty acid binding protein 3734 0,014255 0,2087285 1239,5 232,5 5,331 FABP4 4, adipocyte tudor domain 3363 0,0121881 0,1981221 87,4 16,4 5,329 TDRD9 containing 9 deoxyribonucle 332 0,000338 0,0552439 53,4 10,2 5,235 DNASE2B ase II beta aldehyde dehydrogenas e 5 family, member A1 (succinate- semialdehyde dehydrogenas 3016 0,0101106 0,1832002 146,6 28,3 5,18 ALDH5A1 e) phospholipase C, beta 1 (phosphoinositi 1757 0,0038928 0,1210936 61,4 12 5,117 PLCB1 de-specific)

FERM domain 110 7,73E-05 0,0382725 370,2 72,6 5,099 FRMD4A containing 4A suppressor of cytokine 2276 0,0061685 0,1481822 173,9 34,2 5,085 SOCS1 signaling 1 hypothetical protein 17 1,34E-05 0,0302321 101,1 19,9 5,08 LOC153577 LOC153577 Similar to Calponin-2 (Calponin H2, smooth muscle) (Neutral 2544 0,0075774 0,1628516 73,9 14,9 4,96 LOC642893 calponin) peptidylprolyl isomerase C 1762 0,0039126 0,121407 107,3 22,3 4,812 PPIC (cyclophilin C)

FERM domain 1795 0,0040471 0,1232731 80,7 17 4,747 FRMD4A containing 4A Src-like- adaptor /// Src- 1239 0,0022258 0,0982208 2188 466,7 4,688 SLA like-adaptor peroxisome proliferator- activated receptor 2109 0,0053734 0,1392684 677,5 146,1 4,637 PPARG gamma

TIMP metallopeptida se inhibitor 3 (Sorsby fundus dystrophy, pseudoinflamm 630 0,0007657 0,0664245 515 111,3 4,627 TIMP3 atory) TIMP metallopeptida se inhibitor 3 (Sorsby fundus dystrophy, pseudoinflamm 1435 0,0028138 0,1071379 524 113,7 4,609 TIMP3 atory) Leukotriene B4 848 0,0012319 0,0791194 120,8 26,4 4,576 LTB4R receptor Multiple Gene 4620 0,021198 0,2508282 149,7 32,8 4,564 Symbols NA mitochondrial tumor 872 0,0012655 0,0791194 148,2 32,7 4,532 MTUS1 suppressor 1

FERM domain 881 0,0012804 0,079454 270,6 60 4,51 FRMD4A containing 4A

chromosome 8 open reading 711 0,0009228 0,0708321 153,3 34 4,509 C8orf72 frame 72 594 0,00072 0,0657513 99 22,6 4,381 PRR6 proline rich 6

Receptor tyrosine kinase- like orphan 27 1,67E-05 0,0302321 39,3 9 4,367 ROR1 receptor 1 solute carrier family 1 (glial high affinity glutamate transporter), 1185 0,0020858 0,0961653 294,1 68 4,325 SLC1A3 member 3

Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability 1862 0,0043093 0,1264829 151,6 35,1 4,319 FLT1 factor receptor) protein tyrosine phosphatase- like (proline instead of catalytic arginine), 2654 0,0081664 0,1681297 85,7 20 4,285 PTPLA member A

ribosomal protein S6 kinase, 90kDa, 340 0,0003457 0,0552439 242,2 56,7 4,272 RPS6KA2 polypeptide 2 1923 0,0045537 0,1293549 308,6 72,7 4,245 NA NA solute carrier organic anion transporter family, member 3591 0,013433 0,2043749 58,3 13,8 4,225 SLCO4C1 4C1 Fas apoptotic inhibitory molecule 3 /// Fas apoptotic inhibitory 4044 0,0167209 0,2260671 220 52,2 4,215 FAIM3 molecule 3 kelch domain 863 0,001252 0,0791194 71 16,9 4,201 KLHDC5 containing 5 basic helix- loop-helix domain containing, 5648 0,0299771 0,290155 1111,3 265 4,194 BHLHB3 class B, 3 Nedd4 family interacting 883 0,0012847 0,079454 87,8 21 4,181 NDFIP2 protein 2 Eukaryotic translation initiation factor 20 1,40E-05 0,0302321 168,8 40,5 4,168 EIF2C1 2C, 1 Immunoglobuli n heavy constant alpha 1727 0,0037769 0,1195727 343,3 83,3 4,121 IGHA1 1 amidohydrolas e domain 386 0,0004095 0,0577756 33,8 8,3 4,072 AMDHD1 containing 1 patatin-like phospholipase domain 495 0,0005656 0,0624087 108,6 26,8 4,052 PNPLA3 containing 3 ubiquitin carboxyl- terminal esterase L1 (ubiquitin 625 0,0007593 0,0664236 91,9 22,7 4,048 UCHL1 thiolesterase) Src-like- adaptor /// Src- 1593 0,0033554 0,1151642 1824,6 452 4,037 SLA like-adaptor chromosome 11 open reading frame 284 0,0002744 0,0525339 82,7 20,5 4,034 C11orf45 45

TIMP metallopeptida se inhibitor 3 (Sorsby fundus dystrophy, pseudoinflamm 1351 0,0025626 0,1036037 376,9 94,1 4,005 TIMP3 atory) guanylate cyclase activator 1A 3197 0,0112813 0,1929325 67,2 16,8 4 GUCA1A (retina) 5.5 kb mRNA upregulated in retinoic acid treated HL-60 neutrophilic 843 0,0012186 0,0790355 240,9 60,5 3,982 NA cells GM2 ganglioside 1728 0,0037801 0,1196047 878 221,3 3,967 GM2A activator non-SMC condensin I complex, 2296 0,0062576 0,1489073 709,9 180 3,944 NCAPH subunit H transmembran 729 0,0009562 0,071715 185,4 47,2 3,928 TMEM117 e protein 117

solute carrier family 22 (organic cation transporter), 30 1,74E-05 0,0302321 93,8 24,1 3,892 SLC22A16 member 16 pleckstrin homology domain containing, family A 1231 0,0022106 0,0980647 54,2 14 3,871 PLEKHA5 member 5 TPTE 499 0,0005731 0,0626634 61,9 16 3,869 psiTPTE22 pseudogene phosphatidic acid phosphatase 2715 0,0084609 0,1703866 1008,3 264,3 3,815 PPAP2B type 2B 32 1,81E-05 0,0302321 33,1 8,7 3,805 NA NA Malate dehydrogenas e 1, NAD 3884 0,0154747 0,2178371 162,9 43,1 3,78 MDH1 (soluble) transferrin receptor (p90, 2487 0,007256 0,1594541 152,8 40,5 3,773 TFRC CD71) family with sequence similarity 92, member A1 /// FAM92A1 /// similar to 1885 0,0044102 0,1279192 94,4 25,2 3,746 LOC730572 CG6405-PA

chromosome 8 open reading 1178 0,0020747 0,0961653 179,4 47,9 3,745 C8orf72 frame 72

transmembran 6727 0,0409647 0,3329486 243,3 65,1 3,737 TMEM130 e protein 130 malic enzyme 1, NADP(+)- dependent, 4064 0,0168471 0,2266524 31,5 8,5 3,706 ME1 cytosolic macrophage scavenger 6751 0,041189 0,3335815 184,8 50,1 3,689 MSR1 receptor 1 LIM domain and actin 2890 0,0093392 0,1765702 556,2 151,5 3,671 LIMA1 binding 1 hypothetical protein 1021 0,0016321 0,0873837 48,6 13,3 3,654 LOC286272 LOC286272

Phosphodieste rase 3B, cGMP- 1197 0,0021249 0,0970402 120,9 33,2 3,642 PDE3B inhibited

cytochrome P450, family 4, subfamily V, 2998 0,0100137 0,1825536 42,8 11,8 3,627 CYP4V2 polypeptide 2 HtrA serine 5653 0,0300663 0,2907969 226,8 62,6 3,623 HTRA4 peptidase 4

FERM domain 2767 0,0087787 0,1732398 41,9 11,6 3,612 FRMD4A containing 4A protein kinase, cAMP- dependent, 3780 0,0146005 0,2111806 322,2 89,4 3,604 PRKACB catalytic, beta CDNA FLJ25556 fis, clone 2354 0,0065405 0,1519124 256,2 71,1 3,603 NA JTH02629

phosphodieste rase 3B, cGMP- 148 0,0001225 0,0449393 185,4 51,7 3,586 PDE3B inhibited chromosome 14 open reading frame 1352 0,0025632 0,1036037 73,5 20,5 3,585 C14orf65 65

solute carrier family 6 (neurotransmitt er transporter, betaine/GABA) 157 0,0001304 0,0454116 121,4 34 3,571 SLC6A12 , member 12 peptidylglycine alpha- amidating monooxygenas 237 0,0002189 0,050448 682,7 191,2 3,571 PAM e 5709 0,0305577 0,2926386 94,8 26,6 3,564 FN1 Fibronectin 1 GM2 ganglioside 1837 0,0042158 0,1254704 818,1 230,4 3,551 GM2A activator CDNA FLJ36989 fis, clone BRACE200675 403 0,0004327 0,0577884 3501,3 987,4 3,546 NA 3 phosphatidic acid phosphatase 2492 0,0072711 0,1595295 2284,1 644,8 3,542 PPAP2B type 2B tumor necrosis factor receptor superfamily, member 11a, 1397 0,0026917 0,1053462 131 37 3,541 TNFRSF11A NFKB activator

SPOC domain 1429 0,0028067 0,1071379 227,7 64,3 3,541 SPOCD1 containing 1

SPOC domain 6148 0,0349452 0,3107388 451,9 128,1 3,528 SPOCD1 containing 1

Chromosome 9 open reading 1023 0,0016352 0,0873945 173,9 50,4 3,45 C9orf52 frame 52 protein tyrosine phosphatase, non-receptor type 13 (APO- 1/CD95 (Fas)- associated 25 1,58E-05 0,0302321 24 7 3,429 PTPN13 phosphatase) cholesterol 25- 2242 0,0059923 0,1461325 641,2 187,2 3,425 CH25H hydroxylase integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 63 4,16E-05 0,0353731 51 14,9 3,423 ITGA4 receptor) malic enzyme 1, NADP(+)- dependent, 6604 0,0393031 0,3253932 173,7 50,8 3,419 ME1 cytosolic Protein tyrosine phosphatase, receptor type, N polypeptide 360 0,00037 0,0561938 107,6 31,5 3,416 PTPRN2 2

Chromosome 9 open reading 1289 0,0024046 0,1019668 106,1 31,1 3,412 C9orf52 frame 52 GM2 ganglioside 1611 0,0034234 0,116061 1005,1 297,4 3,38 GM2A activator HEAT repeat 1664 0,0035687 0,1172588 182,5 54 3,38 HEATR5A containing 5A CDNA FLJ41910 fis, clone PEBLM200783 56 3,42E-05 0,0333908 80 23,7 3,376 NA 4 LIM domain and actin 4102 0,0171483 0,2285213 174,1 51,8 3,361 LIMA1 binding 1 CDNA FLJ37694 fis, clone BRHIP201522 1895 0,0044651 0,128789 43,6 13 3,354 NA 4 peptidylglycine alpha- amidating monooxygenas 178 0,0001591 0,0481428 722,1 215,7 3,348 PAM e carboxypeptida 546 0,0006351 0,0635709 95,7 28,6 3,346 CPM se M

tumor necrosis factor receptor superfamily, member 11a, 5088 0,0250846 0,269445 904,3 270,7 3,341 TNFRSF11A NFKB activator integrin, alpha 5559 0,02924 0,2875492 81 24,3 3,333 ITGA6 6

four and a half 5390 0,0276703 0,2806816 961,8 288,8 3,33 FHL1 LIM domains 1

chromosome 3 open reading 62 4,09E-05 0,0353731 64,7 19,5 3,318 C3orf64 frame 64 6358 0,0370162 0,3182035 67 20,2 3,317 FN1 fibronectin 1 Transcribed 1480 0,0029672 0,109553 33 10 3,3 NA locus aldehyde dehydrogenas e 1 family, 2444 0,0069745 0,1560273 129,7 39,3 3,3 ALDH1A2 member A2 transferrin receptor (p90, 2179 0,0056791 0,1424988 5129,6 1559,1 3,29 TFRC CD71) integrin, alpha 3179 0,0111595 0,1919092 79,7 24,3 3,28 ITGA6 6 carboxypeptida 655 0,0008288 0,0691827 632,8 193,6 3,269 CPM se M monoacylglyce rol O- acyltransferase 255 0,0002397 0,0513945 107,4 32,9 3,264 MOGAT1 1 dpy-19-like 3 416 0,0004441 0,0577884 63,3 19,4 3,263 DPY19L3 (C. elegans) dpy-19-like 4 1346 0,0025574 0,1036037 72,9 22,5 3,24 DPY19L4 (C. elegans)

histone cluster 1780 0,0039896 0,1224818 461,8 142,7 3,236 HIST1H2BK 1, H2bk hydroxysteroid (11-beta) dehydrogenas 1251 0,002257 0,0986109 474,3 147 3,227 HSD11B1 e 1

2102 0,0053522 0,1392158 393 122 3,221 EVL Enah/Vasp-like transmembran e 7 superfamily member 4 /// transmembran e 7 superfamily 5798 0,0313019 0,2950284 1804,2 560,7 3,218 TM7SF4 member 4 cytochrome P450, family 27, subfamily A, polypeptide 6811 0,0418149 0,3356673 2088,3 651,7 3,204 CYP27A1 1

174 0,0001552 0,0481428 47,4 14,8 3,203 EVL Enah/Vasp-like Tudor domain 230 0,0002066 0,0487168 179,8 56,2 3,199 TDRD6 containing 6 Transcribed 1205 0,0021475 0,0974395 24,5 7,7 3,182 NA locus STAM binding 5337 0,0272613 0,279243 43,6 13,7 3,182 STAMBPL1 protein-like 1 protein kinase, cAMP- dependent, 2885 0,0093168 0,1765671 1056,4 333,2 3,17 PRKACB catalytic, beta

transient receptor potential cation channel, subfamily V, 282 0,0002729 0,0525339 303,4 96,2 3,154 TRPV2 member 2 GM2 ganglioside 679 0,0008755 0,0701954 1602,5 508,6 3,151 GM2A activator

pyruvate dehydrogenas e phosphatase 1292 0,0024143 0,1021686 33,7 10,7 3,15 PDP2 isoenzyme 2

Pyruvate dehydrogenas e phosphatase 659 0,0008352 0,0692937 101,7 32,4 3,139 PDP2 isoenzyme 2

Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability 2527 0,0074611 0,1614308 206,3 65,8 3,135 FLT1 factor receptor) cornichon homolog 3 2370 0,0066261 0,1528204 63,7 20,4 3,123 CNIH3 (Drosophila) EPH receptor 16 1,34E-05 0,0302321 27,3 8,8 3,102 EPHB1 B1 neuroblastoma breakpoint family, member 1 /// neuroblastoma breakpoint family, member 3 /// neuroblastoma breakpoint family, member 8 /// region containing neuroblastoma breakpoint family, member 8; NBPF1 /// neuroblastoma NBPF3 /// breakpoint NBPF8 /// family, member 6699 0,0405065 0,3305765 120,9 39 3,1 LOC730258 10 monoglyceride 3315 0,0119067 0,1963683 933,5 301,6 3,095 MGLL lipase 5@#$%&- nucleotidase domain 1790 0,0040299 0,1230921 93,7 30,3 3,092 NT5DC1 containing 1

FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte- 1155 0,0020097 0,0950722 151,4 49 3,09 FARP1 derived) WW domain containing transcription 50 3,03E-05 0,0326978 38,6 12,5 3,088 WWTR1 regulator 1 BCL2- associated 353 0,0003598 0,0556372 28,1 9,1 3,088 BAG2 athanogene 2 acylphosphata se 2, muscle 97 6,61E-05 0,0371567 96,8 31,4 3,083 ACYP2 type soluble liver antigen/liver pancreas 140 0,0001154 0,0439272 36,3 11,8 3,076 SLA/LP antigen sialic acid binding Ig-like lectin, 791 0,0010964 0,0757259 151,8 49,6 3,06 SIGLECP3 pseudogene 3 Inositol 1,4,5- trisphosphate 1531 0,0031442 0,1122855 109,8 35,9 3,058 ITPKB 3-kinase B neural precursor cell expressed, developmentall y down- 897 0,0013172 0,0802264 32,4 10,6 3,057 NEDD9 regulated 9 protein arginine methyltransfer 2258 0,0060666 0,1468961 68,5 22,5 3,044 PRMT6 ase 6 monoglyceride lipase /// monoglyceride 5878 0,0320405 0,298029 897,2 295,4 3,037 MGLL lipase

NLR family, CARD domain 195 0,0001747 0,0483249 34,3 11,3 3,035 NLRC4 containing 4 Transcribed 1705 0,0037049 0,1188067 36,7 12,1 3,033 NA locus nuclear receptor subfamily 4, group A, 677 0,0008691 0,0701891 793 261,7 3,03 NR4A3 member 3

four and a half 3578 0,0133702 0,2042096 105 34,8 3,017 FHL1 LIM domains 1 RAB11 family interacting protein 4 (class 502 0,000577 0,062773 45,2 15 3,013 RAB11FIP4 II) retinoic acid receptor responder (tazarotene 113 8,04E-05 0,0382725 25,5 8,5 3 RARRES1 induced) 1

pericentriolar material 1 /// transmembran e phosphatase PCM1 /// with tensin 253 0,0002393 0,0513945 1151,1 384,2 2,996 TPTE homology nuclear factor of activated T- cells, cytoplasmic, calcineurin- 267 0,0002548 0,0521767 62,9 21 2,995 NFATC3 dependent 3 serine dehydratase- 1323 0,0025 0,1033163 111,6 37,4 2,984 SDSL like adenosine 2938 0,0096577 0,1796709 76,4 25,6 2,984 ADA deaminase

histone cluster 2856 0,0092028 0,1761776 1602,5 538,5 2,976 HIST1H2BK 1, H2bk

exostoses 627 0,0007635 0,0664245 93 31,3 2,971 EXTL2 (multiple)-like 2 799 0,0011084 0,0757259 41 13,8 2,971 SORT1 sortilin 1 aldehyde dehydrogenas e 18 family, 1264 0,0022851 0,0988432 43,3 14,6 2,966 ALDH18A1 member A1 TRAF- interacting protein with a forkhead- associated 225 0,0001993 0,0484299 167,5 56,7 2,954 TIFA domain neuroblastoma breakpoint family, member 809 0,0011308 0,0763495 31 10,5 2,952 NBPF1 1 KIAA1908 14 1,13E-05 0,0302321 60,5 20,5 2,951 KIAA1908 protein

immediate early response 1660 0,0035575 0,1171725 115,1 39 2,951 IER5L 5-like Ets homologous 12 8,20E-06 0,0302321 310,5 105,4 2,946 EHF factor

A kinase (PRKA) anchor protein (gravin) 873 0,0012656 0,0791194 153,5 52,1 2,946 AKAP12 12 Proprotein convertase subtilisin/kexin 1947 0,0046265 0,1299198 207,3 70,5 2,94 PCSK5 type 5

FERM domain 2142 0,0055222 0,1409462 47,9 16,3 2,939 FRMD4A containing 4A CDNA FLJ13474 fis, clone PLACE100359 2874 0,0092739 0,1764162 185 63 2,937 NA 3

UDP-N-acetyl- alpha-D- galactosamine: polypeptide N- acetylgalactos aminyltransfer ase 12 3095 0,0106181 0,1874018 907,1 309 2,936 GALNT12 (GalNAc-T12) integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 331 0,0003379 0,0552439 40,7 13,9 2,928 ITGA4 receptor)

cellular retinoic acid binding 4684 0,0217005 0,253301 378,8 129,4 2,927 CRABP2 protein 2 phosphatidic acid phosphatase type 2 domain 1257 0,0022735 0,0987873 35,4 12,1 2,926 PPAPDC2 containing 2 Hypothetical protein 4258 0,0182728 0,2345596 104,9 36 2,914 LOC729013 LOC729013 solute carrier family 18 (vesicular monoamine), 7327 0,0473875 0,3536063 22,7 7,8 2,91 SLC18A2 member 2 galactose mutarotase (aldose 1- 77 5,06E-05 0,0357118 385,1 132,4 2,909 GALM epimerase) zinc finger 134 0,0001062 0,0431325 24,1 8,3 2,904 ZNF320 protein 320 phosphatidic acid phosphatase 2644 0,0080999 0,167497 3709,4 1278,1 2,902 PPAP2B type 2B Wolfram syndrome 1 647 0,0008137 0,0687608 395,6 136,4 2,9 WFS1 (wolframin) ring finger 1442 0,0028463 0,107898 153,4 52,9 2,9 RNF125 protein 125 10 7,20E-06 0,0302321 27,5 9,5 2,895 ASTN2 astrotactin 2 erythrocyte membrane protein band 3064 0,0104311 0,1860573 79,2 27,4 2,891 EPB41L1 4.1-like 1 sema domain, immunoglobuli n domain (Ig), short basic domain, secreted, (semaphorin) 430 0,0004563 0,0577884 531 184,1 2,884 SEMA3C 3C

24- dehydrocholest 5389 0,0276613 0,2806423 244,6 85 2,878 DHCR24 erol reductase zinc finger, DHHC-type 404 0,000433 0,0577884 29,9 10,4 2,875 ZDHHC21 containing 21 inositol 1,4,5- trisphosphate 3150 0,0109354 0,1898073 242,1 84,2 2,875 ITPKB 3-kinase B

Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability 2180 0,0056854 0,1425914 247,6 86,2 2,872 FLT1 factor receptor) hypothetical locus 3346 0,012116 0,1978882 68,3 23,8 2,87 LOC572558 LOC572558 Embigin homolog 1501 0,003052 0,1109355 30,7 10,7 2,869 EMB (mouse) Rho-guanine nucleotide exchange 5846 0,0317278 0,2967222 30,7 10,7 2,869 RGNEF factor glycerol-3- phosphate dehydrogenas 1172 0,0020677 0,0961653 79,1 27,6 2,866 GPD1 e 1 (soluble)

mannosidase, 556 0,0006517 0,0640787 55,8 19,6 2,847 MANEAL endo-alpha-like acyl-CoA thioesterase 2 ACOT2 /// /// acyl-CoA 90 6,17E-05 0,0367348 262,2 92,3 2,841 ACOT1 thioesterase 1

cytochrome P450, family 4, subfamily V, 1766 0,0039384 0,1219045 63 22,2 2,838 CYP4V2 polypeptide 2 erythrocyte membrane protein band 6818 0,0418858 0,3358384 217,6 76,7 2,837 EPB41L2 4.1-like 2 dedicator of 1216 0,0021819 0,097918 106,9 37,7 2,836 DOCK3 cytokinesis 3 transmembran e and tetratricopeptid e repeat 2348 0,0064879 0,1510758 75,8 26,9 2,818 TMTC4 containing 4

coiled-coil- helix-coiled-coil- helix domain 80 5,27E-05 0,0360172 1409,9 501,8 2,81 CHCHD7 containing 7 nuclear transcription factor, X-box 1345 0,0025572 0,1036037 59,3 21,1 2,81 NFXL1 binding-like 1 Wolfram syndrome 1 274 0,0002679 0,0525339 141,9 50,8 2,793 WFS1 (wolframin) glycine cleavage system protein H (aminomethyl carrier) /// similar to Glycine cleavage system H protein, mitochondrial precursor /// similar to Glycine cleavage GCSH /// system H LOC654085 protein, /// mitochondrial 2270 0,0061446 0,1479982 275,6 98,8 2,789 LOC730107 precursor 409 0,000436 0,0577884 180,1 64,6 2,788 FMNL2 formin-like 2 STEAP family 884 0,0012886 0,079454 210,5 75,6 2,784 STEAP3 member 3 family with sequence similarity 92, 2555 0,0076232 0,1631305 68,7 24,7 2,781 FAM92A1 member A1 acetyl- Coenzyme A acetyltransfera se 2 (acetoacetyl Coenzyme A 2038 0,0050615 0,1357888 488,9 176,4 2,772 ACAT2 thiolase) 723 0,0009415 0,0711606 889,3 321,6 2,765 MREG melanoregulin Hypothetical protein 141 0,0001158 0,0439272 158,9 57,6 2,759 MGC34646 MGC34646 family with sequence similarity 20, 1820 0,0041434 0,1242557 104,5 38 2,75 FAM20A member A CDNA FLJ14181 fis, clone NT2RP200430 3499 0,0129469 0,2021636 109,6 39,9 2,747 NA 0 sema domain, immunoglobuli n domain (Ig), short basic domain, secreted, (semaphorin) 1955 0,0046586 0,1302859 99,3 36,2 2,743 SEMA3G 3G short-chain dehydrogenas 1139 0,0019754 0,0946254 688 250,9 2,742 MGC4172 e/reductase adenosine 2708 0,008412 0,1698255 151,4 55,3 2,738 ADA deaminase solute carrier family 26, 526 0,0006154 0,0635709 2064,9 755,9 2,732 SLC26A11 member 11 chromosome 12 open reading frame 106 7,51E-05 0,0382725 234,2 85,8 2,73 C12orf4 4

protein phosphatase 2 (formerly 2A), regulatory subunit B@#$%&@#$ 123 9,43E-05 0,0419175 39,8 14,6 2,726 PPP2R3A %&, alpha ankyrin repeat 1688 0,0036376 0,1177064 39,5 14,5 2,724 ANKRD46 domain 46 amylo-1, 6- glucosidase, 4- alpha- glucanotransfe rase (glycogen debranching enzyme, glycogen storage disease type 375 0,0003995 0,0577756 180 66,1 2,723 AGL III) hypothetical protein 1823 0,0041497 0,1242557 43,3 15,9 2,723 FLJ25416 FLJ25416 CDNA clone IMAGE:440298 871 0,0012654 0,0791194 475,8 174,9 2,72 NA 1 solute carrier family 37 (glycerol-3- phosphate transporter), 537 0,00063 0,0635709 94,7 34,9 2,713 SLC37A3 member 3 tubulin, epsilon 1772 0,0039642 0,1221979 42,8 15,8 2,709 TUBE1 1 zinc finger, 1855 0,0042733 0,1259529 31,7 11,7 2,709 ZMYM1 MYM-type 1 loss of heterozygosity, 11, chromosomal region 2, gene 1022 0,0016334 0,0873837 265,3 98 2,707 LOH11CR2A A family with sequence similarity 20, 2368 0,0066196 0,1528204 57,5 21,3 2,7 FAM20A member A Mature T-cell 458 0,0005016 0,059809 34,5 12,8 2,695 MTCP1 proliferation 1

hect domain and RLD 2 pseudogene 3 /// hect domain and RLD 2 HERC2P3 /// pseudogene 2 HERC2P2 /// /// hypothetical 2576 0,0077907 0,1652859 123,7 45,9 2,695 LOC440248 LOC440248 RAB11 family interacting protein 4 (class II) /// RAB11 family interacting protein 4 (class 2042 0,0050909 0,136262 71,4 26,6 2,684 RAB11FIP4 II) hydroxyacyl- Coenzyme A dehydrogenas 652 0,0008238 0,0689926 128,4 47,9 2,681 HADH e cerebellar degeneration- related protein 234 0,0002085 0,0487168 242,5 90,5 2,68 CDR2 2, 62kDa nuclear receptor subfamily 4, group A, 1623 0,0034524 0,1161645 146,1 54,8 2,666 NR4A3 member 3

phosphoribosyl glycinamide formyltransfera se, phosphoribosyl glycinamide synthetase, phosphoribosyl aminoimidazol 356 0,0003634 0,0556372 22,9 8,6 2,663 GART e synthetase GM2 ganglioside 772 0,0010645 0,075254 5240,7 1970,5 2,66 GM2A activator Fas apoptotic inhibitory molecule 3 /// Fas apoptotic inhibitory 3872 0,0154021 0,2174619 105,6 39,7 2,66 FAIM3 molecule 3 Sp1 transcription 329 0,0003363 0,0552439 44,9 16,9 2,657 SP1 factor Ctr9, Paf1/RNA polymerase II complex component, homolog (S. 1675 0,003609 0,1177064 145,1 54,7 2,653 CTR9 cerevisiae) hect domain 1878 0,004393 0,1278952 117,8 44,4 2,653 HERC2 and RLD 2 motile sperm domain 699 0,0009037 0,070427 199,2 75,1 2,652 MOSPD2 containing 2 CDNA FLJ41690 fis, clone HCASM20094 1639 0,003483 0,1161645 67,6 25,5 2,651 NA 05 dopey family 218 0,000193 0,0483249 165,8 62,6 2,649 DOPEY2 member 2

CD1d molecule /// 6324 0,036737 0,3176095 327,8 124 2,644 CD1D CD1d molecule malic enzyme 3, NADP(+)- dependent, mitochondrial ME3 /// /// protease, 910 0,0013466 0,080907 155,4 58,8 2,643 PRSS23 serine, 23 DKFZP564O DKFZP564O0 101 7,12E-05 0,0382725 20,6 7,8 2,641 0823 823 protein sema domain, immunoglobuli n domain (Ig), short basic domain, secreted, (semaphorin) 345 0,0003492 0,0552439 55,4 21 2,638 SEMA3C 3C

3696 0,0140191 0,2073717 56,8 21,6 2,63 EVL Enah/Vasp-like RRS1 ribosome biogenesis regulator homolog (S. 1342 0,0025503 0,1036037 383,5 145,9 2,629 RRS1 cerevisiae) carboxypeptida 99 6,93E-05 0,0382725 784,8 298,8 2,627 CPM se M 3339 0,0120415 0,1971755 341,7 130,1 2,626 PLXNC1 plexin C1 calcium binding protein 296 0,0002882 0,0532207 69,8 26,6 2,624 CAB39L 39-like Nedd4 family interacting 2105 0,0053668 0,1392684 67,7 25,8 2,624 NDFIP2 protein 2 snail homolog 3460 0,0126606 0,2000306 637,6 243,2 2,622 SNAI3 3 (Drosophila) integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 176 0,0001558 0,0481428 137,2 52,4 2,618 ITGA4 receptor) 725 0,0009474 0,0713031 49,2 18,8 2,617 NA NA N-acyl- phosphatidylet hanolamine- hydrolyzing phospholipase 3789 0,01469 0,2119757 26,9 10,3 2,612 NAPE-PLD D Chemokine- 1391 0,0026777 0,1051826 56,4 21,6 2,611 CKLF like factor 4338 0,0189311 0,2386026 454,8 174,3 2,609 FDX1 ferredoxin 1 TBC1 domain family, member 103 7,31E-05 0,0382725 83,1 31,9 2,605 TBC1D16 16

phosphoserine 513 0,0005939 0,0631894 68,4 26,3 2,601 PSPH phosphatase 5889 0,0321604 0,2985081 56,7 21,8 2,601 11-sept septin 11

GCN1 general control of amino-acid synthesis 1- 209 0,0001877 0,0483249 224 86,2 2,599 GCN1L1 like 1 (yeast) zinc finger 350 0,0003583 0,0556372 73,3 28,2 2,599 ZNF302 protein 302 HD domain 1336 0,0025388 0,1036037 230,6 88,8 2,597 HDDC2 containing 2 1932 0,0045773 0,1294851 35,8 13,8 2,594 DST dystonin mannosidase, 3427 0,0124794 0,1990987 80,8 31,2 2,59 MANEA endo-alpha ets homologous 1604 0,0033987 0,1157798 27,7 10,7 2,589 EHF factor motile sperm domain 1317 0,0024848 0,1029968 250,8 97 2,586 MOSPD2 containing 2 447 0,0004899 0,0595242 11,1 4,3 2,581 MYO6 myosin VI

alpha- methylacyl- 1764 0,003917 0,121407 35,1 13,6 2,581 AMACR CoA racemase CDNA FLJ45600 fis, clone BRTHA302036 578 0,0006972 0,0657513 34,8 13,5 2,578 NA 9

chromosome 4 open reading 119 8,50E-05 0,0390536 23,7 9,2 2,576 C4orf18 frame 18 Transcribed 227 0,0002022 0,0487017 22,4 8,7 2,575 NA locus acetyl- Coenzyme A carboxylase 1829 0,0041587 0,1242557 120 46,6 2,575 ACACA alpha Hypothetical protein 1872 0,004379 0,1278386 37,6 14,6 2,575 MGC33302 MGC33302

UDP-N-acetyl- alpha-D- galactosamine: polypeptide N- acetylgalactos aminyltransfer ase 12 2509 0,0073494 0,1601548 1493,9 580,2 2,575 GALNT12 (GalNAc-T12) CDNA clone IMAGE:440298 653 0,000824 0,0689926 741,3 288 2,574 NA 1 B-cell CLL/lymphoma 11A (zinc finger 2426 0,006908 0,1555897 64,1 24,9 2,574 BCL11A protein) presenilin 2 (Alzheimer 1250 0,0022551 0,0986109 149 57,9 2,573 PSEN2 disease 4) chaperonin containing TCP1, subunit 1724 0,0037738 0,1195727 62 24,1 2,573 CCT5 5 (epsilon)

Amyloid beta (A4) precursor- 949 0,0014359 0,0827269 89,2 34,7 2,571 APLP2 like protein 2 ataxia telangiectasia and Rad3 related /// similar to ataxia telangiectasia ATR /// and Rad3 3248 0,0115021 0,1935848 59,1 23 2,57 LOC648152 related protein

phosphoribosyl glycinamide formyltransfera se, phosphoribosyl glycinamide synthetase, phosphoribosyl aminoimidazol 312 0,0003114 0,0541231 224 87,2 2,569 GART e synthetase

phosphodieste rase 3B, cGMP- 584 0,0007032 0,0657513 88,1 34,3 2,569 PDE3B inhibited

G1 to S phase transition 2 /// G1 to S phase 1200 0,0021312 0,0970402 109,1 42,5 2,567 GSPT2 transition 2

822 0,0011619 0,0772833 127 49,5 2,566 ARSB arylsulfatase B SH3 and PX 96 6,45E-05 0,0367348 208,5 81,3 2,565 SH3PXD2A domains 2A histone 35 2,08E-05 0,0312927 55,9 21,8 2,564 HDAC9 deacetylase 9 pericentriolar 381 0,000406 0,0577756 944,7 368,9 2,561 PCM1 material 1 chromosome 20 open reading frame 974 0,0015013 0,0842668 21,5 8,4 2,56 C20orf133 133 4208 0,0179224 0,2327543 58 22,7 2,555 RTN1 reticulon 1 Transcribed 718 0,0009319 0,0708877 100,4 39,4 2,548 NA locus potassium voltage-gated channel, Isk- related family, 64 4,21E-05 0,0353731 46 18,1 2,541 KCNE1 member 1 spastic paraplegia 3A (autosomal 1556 0,0032507 0,1138946 83,4 32,9 2,535 SPG3A dominant) sialic acid binding Ig-like 2583 0,0078114 0,1652945 133,6 52,7 2,535 SIGLEC10 lectin 10 RAB33A, member RAS oncogene 6094 0,0343401 0,3080973 164 64,7 2,535 RAB33A family peptidylglycine alpha- amidating monooxygenas 401 0,0004307 0,0577884 132,5 52,3 2,533 PAM e F-box protein 2709 0,0084144 0,1698255 42,3 16,7 2,533 FBXO15 15 zinc finger 2004 0,004898 0,1335438 59,5 23,5 2,532 ZNF124 protein 124

Homo sapiens, Similar to LOC169932, clone IMAGE:44992 870 0,0012641 0,0791194 179,6 71 2,53 NA 03, mRNA Transmembran 212 0,0001907 0,0483249 13,1 5,2 2,519 TMEM116 e protein 116

chromosome 3 open reading 593 0,0007195 0,0657513 97,2 38,6 2,518 C3orf23 frame 23 Transcribed 1712 0,0037349 0,1192668 34,2 13,6 2,515 NA locus testis expressed 979 0,0015165 0,0846932 253,6 101 2,511 TEX2 sequence 2 CDNA FLJ11489 fis, clone HEMBA10019 3631 0,0136478 0,2052986 31,1 12,4 2,508 NA 15 ets homologous 51 3,05E-05 0,0326978 37,1 14,8 2,507 EHF factor

solute carrier family 30 (zinc transporter), 160 0,0001338 0,045722 115,8 46,2 2,506 SLC30A5 member 5 zinc binding alcohol dehydrogenas e, domain 88 6,05E-05 0,0367348 116,3 46,5 2,501 ZADH2 containing 2 CDNA FLJ43676 fis, clone SYNOV40091 1600 0,0033875 0,1157572 36,5 14,6 2,5 NA 29 myotubularin related protein 1103 0,0018618 0,0922251 150,6 60,3 2,498 MTMR2 2 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal 69 4,56E-05 0,0355773 35,6 14,3 2,49 AMMECR1 region, gene 1

transducin-like enhancer of split 1 (E(sp1) homolog, 665 0,0008464 0,0695894 50,5 20,3 2,488 TLE1 Drosophila)

angiogenic factor with G patch and FHA 83 5,50E-05 0,0360595 269,1 108,2 2,487 AGGF1 domains 1 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 2659 0,0082027 0,1686659 66,9 26,9 2,487 ITGA3 receptor) Hypothetical protein 5946 0,0327262 0,3009258 55,2 22,2 2,486 LOC339290 LOC339290

ribonuclease L (2@#$%&,5@ #$%&- oligoisoadenyl ate synthetase- 72 4,74E-05 0,0357118 208,2 84 2,479 RNASEL dependent) WD repeat 358 0,0003643 0,0556372 406,3 164 2,477 WDR7 domain 7

steroid 5 alpha- reductase 2- 1425 0,0027912 0,1070725 326,1 131,8 2,474 SRD5A2L like solute carrier family 12 (sodium/potass ium/chloride transporters), 1003 0,0015787 0,0860573 24,2 9,8 2,469 SLC12A2 member 2 enolase superfamily 3515 0,0130097 0,2023084 231,6 93,8 2,469 ENOSF1 member 1 family with sequence similarity 72, member A /// similar to family with sequence similarity 72, member A /// similar to FAM72A /// family with LOC653820 sequence /// similarity 72, 3157 0,0109983 0,1904262 176 71,3 2,468 LOC729533 member A hypothetical protein 2911 0,0094613 0,17766 41,9 17 2,465 FLJ32549 FLJ32549 glycerol-3- phosphate dehydrogenas 805 0,0011196 0,0760424 51,5 20,9 2,464 GPD1 e 1 (soluble) Baculoviral IAP repeat- 1224 0,0021951 0,0979999 27,1 11 2,464 BIRC1 containing 1

GCN1 general control of amino-acid synthesis 1- 423 0,0004503 0,0577884 271,4 110,2 2,463 GCN1L1 like 1 (yeast) propionyl Coenzyme A carboxylase, alpha 687 0,0008821 0,0701954 32 13 2,462 PCCA polypeptide DnaJ (Hsp40) homolog, subfamily C, 508 0,0005836 0,0628117 18,7 7,6 2,461 DNAJC6 member 6 family with sequence similarity 89, 3182 0,011181 0,1921 111 45,1 2,461 FAM89A member A Transcribed 357 0,000364 0,0556372 46,5 18,9 2,46 NA locus

pirin (iron- binding nuclear 676 0,0008688 0,0701891 218,4 88,8 2,459 PIR protein)

chromosome 1 open reading 3434 0,0125467 0,1997644 36,6 14,9 2,456 C1orf115 frame 115 hypothetical protein 1741 0,0038348 0,1203258 91,5 37,3 2,453 LOC56757 LOC56757 solute carrier family 29 (nucleoside transporters), 135 0,0001065 0,0431325 593,7 242,2 2,451 SLC29A3 member 3 Rho GTPase activating 2086 0,0052777 0,1383309 259 105,8 2,448 ARHGAP25 protein 25 serine threonine kinase 39 (STE20/SPS1 homolog, 129 0,0001026 0,0431325 120,9 49,4 2,447 STK39 yeast) peptidylprolyl isomerase C 2751 0,0086858 0,1726267 27,4 11,2 2,446 PPIC (cyclophilin C) cytokine inducible SH2- containing 3617 0,0135441 0,2047342 277,5 113,5 2,445 CISH protein ubiquitin specific 1944 0,0046211 0,1299198 28,6 11,7 2,444 USP46 peptidase 46

transducin-like enhancer of split 1 (E(sp1) homolog, 2259 0,0060727 0,1469696 274,5 112,5 2,44 TLE1 Drosophila) hypothetical protein 1152 0,0020015 0,0949931 63,4 26 2,438 FLJ20581 FLJ20581 hypothetical protein 318 0,0003178 0,0546406 58,9 24,2 2,434 FLJ21908 FLJ21908 Hypothetical protein 196 0,0001768 0,0483249 296 121,7 2,432 MGC34646 MGC34646 CDNA FLJ31107 fis, clone IMR32200015 6514 0,0384062 0,3223518 179 73,6 2,432 NA 2 interferon gamma receptor 1 /// interferon gamma 264 0,0002524 0,0521767 1640,3 675,4 2,429 IFNGR1 receptor 1

CSRP2 1304 0,0024577 0,1029552 49,8 20,5 2,429 CSRP2BP binding protein 1419 0,0027723 0,1067259 43,7 18 2,428 KIAA1212 KIAA1212

transient receptor potential cation channel, subfamily V, 834 0,0011991 0,0786101 890,1 366,7 2,427 TRPV2 member 2 4189 0,0177542 0,2317274 126,7 52,2 2,427 SUOX sulfite oxidase 610 0,0007352 0,0657513 1873,2 772,1 2,426 MREG melanoregulin zinc finger 1423 0,002782 0,106891 29,6 12,2 2,426 ZNF322B protein 322B sec1 family domain 689 0,0008887 0,070427 34,4 14,2 2,423 SCFD2 containing 2 KIAA0738 6025 0,0335931 0,3048469 36,1 14,9 2,423 KIAA0738 gene product Transcribed 2653 0,008166 0,1681297 111,4 46 2,422 NA locus DENN/MADD domain 4864 0,0231448 0,2599793 368,1 152 2,422 DENND2D containing 2D Transcribed 3247 0,0115009 0,1935848 33,4 13,8 2,42 NA locus 1710 0,0037298 0,1192554 46,1 19,1 2,414 DST dystonin methylenetetra hydrofolate dehydrogenas e (NADP+ dependent) 1- 2161 0,0055879 0,1413783 111 46 2,413 MTHFD1L like 5650 0,0299922 0,2902343 20,5 8,5 2,412 NA NA beta-site APP- cleaving 6668 0,0401631 0,3293218 125,6 52,1 2,411 BACE1 enzyme 1

PMS1 postmeiotic segregation increased 1 (S. 6792 0,0416733 0,3354559 119,1 49,4 2,411 PMS1 cerevisiae)

chromosome 8 open reading 1272 0,0023197 0,0997088 134,7 55,9 2,41 C8orf38 frame 38 hypothetical protein 1574 0,0032869 0,1141749 63,6 26,4 2,409 FLJ20581 FLJ20581 Transcribed 146 0,0001173 0,0439272 96,8 40,2 2,408 NA locus desmoglein 1 /// zinc finger, DSG1 /// H2C2 domain 778 0,0010749 0,0753005 84,5 35,1 2,407 ZH2C2 containing WD repeat 2817 0,0090236 0,1750784 144,3 60 2,405 WDR40A domain 40A DnaJ (Hsp40) homolog, subfamily C, 261 0,0002503 0,0521767 37,5 15,6 2,404 DNAJC16 member 16 chromosome 10 open reading frame 4850 0,0230026 0,2593128 63,2 26,3 2,403 C10orf6 6 548 0,00064 0,063854 126,7 52,8 2,4 NA NA Rho GTPase activating 2308 0,0063225 0,149757 194,2 80,9 2,4 ARHGAP25 protein 25 Cbp/p300- interacting transactivator, with Glu/Asp- rich carboxy- terminal 2783 0,0088265 0,173406 712 296,7 2,4 CITED2 domain, 2 chromosome 1 open reading frame 25 /// chromosome 1 open reading 4760 0,0223009 0,2560628 95 39,6 2,399 C1orf25 frame 25 Zinc finger 2067 0,0051888 0,1372509 57,8 24,1 2,398 ZNF528 protein 528 B-cell CLL/lymphoma 11A (zinc finger 3599 0,0134722 0,2043749 116,3 48,5 2,398 BCL11A protein)

7337 0,0475151 0,3540804 64,5 26,9 2,398 FBXO9 F-box protein 9

Full-length cDNA clone CS0DK008YI0 9 of HeLa cells Cot 25- normalized of Homo sapiens 156 0,0001285 0,0450368 379,8 158,5 2,396 NA (human) reticulon 4 1171 0,0020658 0,0961653 48,1 20,1 2,393 RTN4R receptor

CD33 469 0,000517 0,0602236 360,4 150,8 2,39 CD33L3 molecule-like 3

transmembran 1877 0,0043918 0,1278952 276,9 115,9 2,389 TMEM135 e protein 135

2087 0,005282 0,1383372 28,9 12,1 2,388 FBXO9 F-box protein 9

solute carrier family 30 (zinc transporter), 3322 0,0119427 0,1965014 16 6,7 2,388 SLC30A5 member 5 acetyl- Coenzyme A acetyltransfera se 1 (acetoacetyl Coenzyme A 145 0,000117 0,0439272 513,3 215 2,387 ACAT1 thiolase) otoancorin /// similar to OTOA /// otoancorin 295 0,0002878 0,0532207 199,1 83,4 2,387 LOC653786 isoform 2 Transcribed 147 0,000122 0,0449393 47 19,7 2,386 NA locus carboxypeptida 138 0,0001111 0,0439272 958,9 402,2 2,384 CPM se M BRI3 binding 675 0,0008685 0,0701891 123,9 52 2,383 BRI3BP protein suppressor of cytokine 2457 0,0070646 0,1572068 36,2 15,2 2,382 SOCS1 signaling 1 potassium channel tetramerisation domain 815 0,0011421 0,0766188 18,8 7,9 2,38 KCTD3 containing 3

MYC induced 281 0,0002714 0,0525339 89,7 37,7 2,379 MINA nuclear antigen HEAT repeat 3374 0,0122509 0,1984192 64,7 27,2 2,379 HEATR3 containing 3 Ets homologous 646 0,0008072 0,0683184 57,3 24,1 2,378 EHF factor 311 0,0003084 0,0541231 163,3 68,8 2,374 FMNL2 formin-like 2 lymphocyte 250 0,0002343 0,0511462 179,4 75,7 2,37 LY9 antigen 9 Mannosidase, alpha, class 2243 0,005995 0,1461331 908,1 383,2 2,37 MAN1A1 1A, member 1 Galactose mutarotase (aldose 1- 128 0,0001007 0,0430138 383,8 162,1 2,368 GALM epimerase) ubiquitin specific 1191 0,002116 0,0969771 38,1 16,1 2,366 USP46 peptidase 46

Ubiquitin B (UBB) mRNA, 3@#$%& UTR and genetic suppressor 3737 0,0142742 0,2087933 79,6 33,7 2,362 NA element WW domain containing transcription 5069 0,0248815 0,2683756 11,8 5 2,36 WWTR1 regulator 1 hypothetical protein 179 0,0001605 0,0481428 459,2 194,8 2,357 FLJ90013 FLJ90013 Hypothetical protein 1758 0,0038936 0,1210936 1349,8 572,8 2,356 LOC162073 LOC162073 prostaglandin- endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenas 2587 0,0078303 0,1654896 1101,1 467,5 2,355 PTGS1 e) zinc finger 3664 0,0138267 0,206325 17,9 7,6 2,355 ZNF253 protein 253 hypothetical protein 214 0,0001919 0,0483249 255,4 108,5 2,354 LOC203411 LOC203411 erythrocyte membrane protein band 3967 0,0160638 0,221358 553,2 235,1 2,353 EPB41L2 4.1-like 2 wingless-type MMTV integration site family, member 5368 0,0274719 0,2798111 32,7 13,9 2,353 WNT5B 5B ganglioside- induced differentiation- associated 180 0,0001608 0,0481428 16,2 6,9 2,348 GDAP1 protein 1

oxysterol binding protein- 81 5,37E-05 0,0360595 1157,2 493 2,347 OSBPL1A like 1A

Zinc finger and BTB domain 3099 0,0106326 0,1874018 129,3 55,1 2,347 ZBTB25 containing 25 membrane- associated ring finger (C3HC4) 6878 0,0423748 0,3368398 28,4 12,1 2,347 03-mars 3 activating signal cointegrator 1 complex 131 0,0001049 0,0431325 184,8 78,8 2,345 ASCC3 subunit 3 prostaglandin- endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenas 6050 0,0338667 0,3060039 215 91,7 2,345 PTGS1 e) Sp1 transcription 73 4,80E-05 0,0357118 33,5 14,3 2,343 SP1 factor presenilin 2 (Alzheimer 1052 0,0017054 0,0886327 157,6 67,3 2,342 PSEN2 disease 4)

Diacylglycerol kinase, gamma 3224 0,0114043 0,1933658 23,4 10 2,34 DGKG 90kDa 905 0,0013329 0,0805159 28,5 12,2 2,336 PLXNA2 plexin A2 Cdk5 and Abl enzyme 1431 0,00281 0,1071379 107,2 45,9 2,336 CABLES1 substrate 1 CDNA clone IMAGE:530349 2289 0,0062231 0,1486448 32 13,7 2,336 NA 9

solute carrier family 30 (zinc transporter), 43 2,56E-05 0,0312927 379,3 162,5 2,334 SLC30A5 member 5 SWI/SNF- related, matrix- associated actin- dependent regulator of chromatin, subfamily a, containing 323 0,0003257 0,0549787 152,8 65,6 2,329 SMARCAD1 DEAD/H box 1 DnaJ (Hsp40) homolog, subfamily C, 493 0,0005641 0,0624087 168,6 72,4 2,329 DNAJC10 member 10 hypothetical protein 2965 0,0098063 0,1807168 99,2 42,6 2,329 LOC285550 LOC285550 ferrochelatase (protoporphyria 3688 0,013982 0,2072847 62,4 26,8 2,328 FECH ) transducin 6065 0,0340259 0,3067086 747,2 321 2,328 TBL2 (beta)-like 2 acyl-CoA 2361 0,0065854 0,1525018 47,9 20,6 2,325 ACOT4 thioesterase 4 glucose-6- phosphate dehydrogenas 792 0,0010972 0,0757259 603,6 259,8 2,323 G6PD e RAB7B, member RAS oncogene 6535 0,0386107 0,3230359 367,1 158 2,323 RAB7B family Transcribed locus, weakly similar to XP_534331.2 similar to ORF2 [Canis 2925 0,0095608 0,1787134 40,6 17,5 2,32 NA familiaris] structural maintenance of chromosomes 4593 0,0209389 0,2492097 42,2 18,2 2,319 SMC2 2 ataxia telangiectasia and Rad3 6173 0,0352058 0,3117492 209,4 90,3 2,319 ATR related DnaJ (Hsp40) homolog, subfamily C, 1063 0,0017359 0,0892854 155,8 67,2 2,318 DNAJC10 member 10

zinc finger and BTB domain containing 8 /// similar to zinc finger and BTB ZBTB8 /// domain 3394 0,0123289 0,1984223 34,3 14,8 2,318 LOC730411 containing 8 echinoderm microtubule associated 2790 0,0088842 0,1741017 191,5 82,7 2,316 EML4 protein like 4 caspase 7, apoptosis- related cysteine 3103 0,0106419 0,1874018 391,4 169,1 2,315 CASP7 peptidase 6261 0,0360662 0,3149528 1474,9 637,7 2,313 FDX1 ferredoxin 1 acyl- Coenzyme A oxidase 1, 124 9,74E-05 0,0429463 188 81,3 2,312 ACOX1 palmitoyl sialic acid binding Ig-like 3252 0,0115248 0,1936505 1507,8 653,1 2,309 SIGLEC10 lectin 10 Uroporphyrino gen III synthase (congenital erythropoietic 964 0,0014884 0,0839343 42,7 18,5 2,308 UROS porphyria)

Chromosome 8 open reading 3929 0,0157883 0,2197061 17,3 7,5 2,307 C8orf72 frame 72

alpha- methylacyl- 1507 0,0030577 0,1109355 16,6 7,2 2,306 AMACR CoA racemase MyoD family inhibitor domain containing /// MyoD family inhibitor domain 24 1,55E-05 0,0302321 642,5 278,7 2,305 MDFIC containing Transcribed 1783 0,003997 0,1225664 27,2 11,8 2,305 NA locus

chromosome 9 open reading 5741 0,0308657 0,2939124 257,5 111,7 2,305 C9orf52 frame 52 Methylmalonic aciduria (cobalamin deficiency) 5227 0,02629 0,2749963 26,5 11,5 2,304 MMAA cblA type selenocysteine 286 0,0002748 0,0525339 121 52,6 2,3 SCLY lyase WD repeat 758 0,0010203 0,0735843 142,3 61,9 2,299 WDR36 domain 36 apoptosis- inducing factor, mitochondrion- associated, 2 /// apoptosis- inducing factor, mitochondrion- 2090 0,0052979 0,1385946 252,4 109,8 2,299 AIFM2 associated, 2

Homo sapiens, clone IMAGE:43986 5803 0,0313229 0,2950284 36,1 15,7 2,299 NA 57, mRNA CDNA FLJ26557 fis, clone 6808 0,041807 0,3356673 37,7 16,4 2,299 NA LNF01992 Transcribed 3294 0,011762 0,1951534 47,8 20,8 2,298 NA locus CDNA clone IMAGE:479709 5244 0,0264373 0,2755518 19,3 8,4 2,298 NA 9 Rho-guanine nucleotide exchange 4946 0,0237944 0,2630325 44,8 19,5 2,297 RGNEF factor N- acylsphingosin e amidohydrolas e (acid 557 0,0006528 0,0640787 2825,1 1230,5 2,296 ASAH1 ceramidase) 1 SET domain, 184 0,0001645 0,0481428 142,7 62,2 2,294 SETDB2 bifurcated 2 phosphotrieste 4933 0,0236897 0,2625652 274,4 119,6 2,294 PTER rase related FYVE and coiled-coil domain 151 0,0001258 0,0449393 85,3 37,2 2,293 FYCO1 containing 1 mannosidase, alpha, class 7180 0,045687 0,3479021 259,7 113,3 2,292 MAN1A1 1A, member 1

protein kinase, cAMP- dependent, regulatory, type I, alpha (tissue specific 259 0,0002477 0,0521767 438,1 191,2 2,291 PRKAR1A extinguisher 1) aldo-keto reductase family 1, member B1 (aldose 1941 0,0046089 0,1298257 941,1 410,7 2,291 AKR1B1 reductase) myosin, light chain 9, 2674 0,0082662 0,1690181 29,1 12,7 2,291 MYL9 regulatory 4966 0,0239682 0,2638867 763,8 333,4 2,291 KIAA0100 KIAA0100 hypothetical protein 454 0,0004971 0,0597118 27,2 11,9 2,286 FLJ32549 FLJ32549 Mannosidase, alpha, class 727 0,0009481 0,0713031 319,2 139,8 2,283 MAN2A1 2A, member 1 motile sperm domain 924 0,0013873 0,082042 541,2 237,1 2,283 MOSPD1 containing 1 Hypothetical protein 4188 0,0177536 0,2317274 114,1 50 2,282 FLJ25006 FLJ25006 leucine carboxyl methyltransfer 5206 0,0261549 0,2745585 97,2 42,6 2,282 LCMT2 ase 2 3- hydroxyisobuty rate dehydrogenas 1538 0,003191 0,1132377 91,7 40,2 2,281 HIBADH e histidine triad nucleotide binding protein 4303 0,0186415 0,2368636 61,6 27 2,281 HINT3 3 Aminopeptidas 4376 0,0192707 0,2407737 103,8 45,5 2,281 NPEPL1 e-like 1

MRNA; cDNA DKFZp451K06 3 (from clone DKFZp451K06 3403 0,0123568 0,1984223 24,4 10,7 2,28 NA 3)

3@#$%&(2@# $%&), 5@#$%&- bisphosphate 946 0,0014318 0,0826707 145,2 63,7 2,279 BPNT1 nucleotidase 1 CDNA FLJ34034 fis, clone FCBBF200467 3119 0,0107191 0,187877 91,8 40,3 2,278 NA 1 7268 0,0467609 0,3517683 223 97,9 2,278 NA NA

5- aminoimidazol e-4- carboxamide ribonucleotide formyltransfera se/IMP 66 4,27E-05 0,0353731 574,9 252,5 2,277 ATIC cyclohydrolase elaC homolog 988 0,0015513 0,0856868 39,8 17,5 2,274 ELAC1 1 (E. coli)

four and a half 5858 0,0318241 0,2970267 115 50,6 2,273 FHL1 LIM domains 1 mitochondrial ribosomal 2191 0,0057303 0,142996 18,4 8,1 2,272 MRPS25 protein S25 carboxypeptida 65 4,23E-05 0,0353731 107,4 47,3 2,271 CPM se M

G elongation factor, 618 0,0007442 0,0657513 42 18,5 2,27 GFM2 mitochondrial 2

glutamyl-tRNA synthetase 2 (mitochondrial) 112 7,96E-05 0,0382725 83,9 37 2,268 EARS2 (putative) sec1 family domain 397 0,0004206 0,0577884 269,7 118,9 2,268 SCFD2 containing 2 malate dehydrogenas e 1, NAD 599 0,0007245 0,0657513 6013,4 2651,7 2,268 MDH1 (soluble) 788 0,0010901 0,0756026 54,2 23,9 2,268 CYTL1 cytokine-like 1

NIMA (never in mitosis gene a)- related kinase 4257 0,0182607 0,2345322 49,2 21,7 2,267 NEK9 9

protein phosphatase 2 (formerly 2A), regulatory subunit B@#$%&@#$ 1605 0,0034024 0,1157798 80 35,3 2,266 PPP2R3A %&, alpha

1911 0,0045199 0,1293174 239,9 105,9 2,265 CD84 CD84 molecule tripartite motif- 656 0,0008316 0,0691996 626,4 276,9 2,262 TRIM14 containing 14

vitamin K epoxide reductase complex, 1670 0,0035875 0,117453 151,7 67,1 2,261 VKORC1L1 subunit 1-like 1

ARP8 actin- related protein 8 homolog 702 0,0009065 0,070427 77,6 34,4 2,256 ACTR8 (yeast) BRCA1/BRCA 2-containing complex, 906 0,0013342 0,0805159 157,6 69,9 2,255 BRCC3 subunit 3

caspase recruitment domain family, 1814 0,0041247 0,1241646 121 53,7 2,253 CARD14 member 14 solute carrier family 35, 33 1,86E-05 0,0302321 82,2 36,5 2,252 SLC35B4 member B4 CD22 molecule /// myelin CD22 /// associated 431 0,0004565 0,0577884 61,9 27,5 2,251 MAG glycoprotein Crn, crooked neck-like 1 2465 0,0070923 0,1572947 110,2 49 2,249 CRNKL1 (Drosophila) hypothetical protein 2582 0,0078074 0,1652945 21,8 9,7 2,247 LOC283357 LOC283357 3320 0,0119356 0,1965014 2548,5 1134,2 2,247 AQP9 aquaporin 9 1810 0,0041203 0,1241646 359,2 160,1 2,244 10-sept septin 10 (clone 1NIB-4) normalized cDNA library 3451 0,0126294 0,1999997 643,4 287 2,242 NA sequence

G elongation factor, 1451 0,0028668 0,1080236 48,4 21,6 2,241 GFM2 mitochondrial 2 Coronin, actin binding 4810 0,0226946 0,257834 239,2 106,8 2,24 CORO2A protein, 2A GM2 ganglioside 943 0,0014272 0,0826707 8364 3735,8 2,239 GM2A activator

similar to FUS- interacting serine-arginine- rich protein 1 (TLS- associated protein with Ser-Arg repeats) (TLS- associated protein with SR repeats) (TASR) (TLS- associated serine-arginine protein) (TLS- associated SR protein) (Neural- specific SR 1793 0,0040387 0,1231132 40,3 18 2,239 LOC727922 protein...

chromosome 2 open reading 485 0,0005476 0,0615795 88,4 39,5 2,238 C2orf43 frame 43

A kinase (PRKA) anchor 2496 0,0072859 0,159598 92,4 41,3 2,237 AKAP5 protein 5

NLR family, CARD domain 914 0,001355 0,0810038 311,3 139,2 2,236 NLRC4 containing 4 MRNA full length insert cDNA clone EUROIMAGE 1494 0,0030076 0,1100334 1242,2 556,1 2,234 NA 1509279

caspase recruitment domain family, 4892 0,0233853 0,2613637 106,5 47,7 2,233 CARD14 member 14 mitochondrial intermediate 288 0,0002768 0,0525487 112,5 50,4 2,232 MIPEP peptidase aminolevulinat e, delta-, 290 0,0002845 0,0532207 61,6 27,6 2,232 ALAD dehydratase Ceramide 2151 0,0055595 0,1413137 85,9 38,5 2,231 CERKL kinase-like 680 0,0008759 0,0701954 259,6 116,4 2,23 NA NA sel-1 suppressor of lin-12-like (C. 1000 0,0015731 0,0859576 174,8 78,4 2,23 SEL1L elegans) hypothetical protein 1523 0,0031148 0,1117752 530,1 237,7 2,23 LOC729678 LOC729678 D-aspartate 3433 0,0125418 0,1997445 76,9 34,5 2,229 DDO oxidase exonuclease domain 206 0,0001849 0,0483249 100,6 45,2 2,226 EXOD1 containing 1 leucine-rich repeat- containing G protein- coupled 1559 0,0032549 0,1138946 11,8 5,3 2,226 LGR4 receptor 4

lipoma HMGIC 1157 0,002012 0,0950722 16,9 7,6 2,224 LHFP fusion partner protein phosphatase 1, regulatory 3087 0,0105782 0,1873544 121,9 54,8 2,224 PPP1R3D subunit 3D DnaJ (Hsp40) homolog, subfamily C, 2440 0,0069551 0,1557913 261,9 117,8 2,223 DNAJC10 member 10

protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta 2221 0,0058587 0,1441488 105,7 47,6 2,221 PPP2R1B isoform

progestin and adipoQ receptor family 2707 0,0084102 0,1698255 43,7 19,7 2,218 PAQR8 member VIII phosphotrieste 3513 0,0129917 0,2021979 368,6 166,2 2,218 PTER rase related MRNA; cDNA DKFZp779M24 22 (from clone DKFZp779M24 671 0,0008585 0,069812 318,6 143,7 2,217 NA 22) zinc finger protein 320 /// hypothetical ZNF320 /// protein 34 1,88E-05 0,0302321 772,6 348,6 2,216 FLJ38482 FLJ38482

3767 0,0145284 0,2108234 25,7 11,6 2,216 FBXO9 F-box protein 9 dihydrolipoami de S- acetyltransfera se (E2 component of pyruvate dehydrogenas 315 0,000312 0,0541231 162,2 73,3 2,213 DLAT e complex) prostaglandin- endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenas 3275 0,0116264 0,1940988 1211,3 547,3 2,213 PTGS1 e)

diazepam binding inhibitor (GABA receptor modulator, acyl- Coenzyme A binding 1456 0,0028819 0,1082197 2844,1 1285,7 2,212 DBI protein) chromosome 14 open reading frame 28 /// C14orf28 /// synaptophysin- 941 0,0014186 0,082425 19 8,6 2,209 SYPL2 like 2 amidohydrolas e domain 71 4,62E-05 0,0355773 121 54,8 2,208 AMDHD2 containing 2 soluble liver antigen/liver pancreas 109 7,71E-05 0,0382725 21,2 9,6 2,208 SLA/LP antigen

alpha- methylacyl- 945 0,0014309 0,0826707 26,7 12,1 2,207 AMACR CoA racemase transmembran e and coiled- coil domain 1581 0,0033041 0,1142231 97,1 44 2,207 TMCC1 family 1 SET domain, 167 0,0001429 0,0467848 111,2 50,4 2,206 SETDB2 bifurcated 2 2862 0,0092242 0,176217 125,7 57 2,205 KIAA1797 KIAA1797 6181 0,0352432 0,3117492 67,1 30,5 2,2 PLXNC1 plexin C1

methionine adenosyltransf 733 0,0009654 0,0720099 245 111,4 2,199 MAT2A erase II, alpha Archaemetzinc 3283 0,0117065 0,1949598 31 14,1 2,199 AMZ2 ins-2

Transmembran 983 0,0015326 0,0852441 125 56,9 2,197 TMEM165 e protein 165 Rho-related BTB domain 2996 0,0100058 0,1825536 33,4 15,2 2,197 RHOBTB3 containing 3 ferrochelatase (protoporphyria 313 0,0003117 0,0541231 143,6 65,4 2,196 FECH )

chromosome 6 open reading 514 0,0005948 0,0631894 470,1 214,2 2,195 C6orf108 frame 108 5145 0,0255998 0,272031 201,9 92 2,195 NMB neuromedin B testis specific, 21 1,45E-05 0,0302321 29,4 13,4 2,194 TSGA14 14 deleted in liver 970 0,001492 0,0839343 44,3 20,2 2,193 DLC1 cancer 1 asparagine- linked glycosylation 14 homolog 1472 0,0029478 0,1094911 223,7 102 2,193 ALG14 (yeast)

pericentriolar material 1 /// transmembran e phosphatase PCM1 /// with tensin 1631 0,003473 0,1161645 388,1 177,1 2,191 TPTE homology

p21/Cdc42/Ra c1-activated kinase 1 (STE20 homolog, yeast) /// PAK1 /// vesicle docking 372 0,000396 0,0577756 793,5 362,7 2,188 VDP protein p115 chromosome 14 open reading frame 636 0,0007794 0,0669919 57,1 26,1 2,188 C14orf1 1 isocitrate dehydrogenas e 3 (NAD+) 1844 0,0042424 0,1257495 246,8 112,8 2,188 IDH3A alpha hypothetical protein 1016 0,0016109 0,0866252 69,3 31,7 2,186 FLJ20581 FLJ20581 insulin- degrading 121 9,00E-05 0,0405581 217,6 99,6 2,185 IDE enzyme chromosome 21 open reading frame 986 0,0015388 0,0853285 20,1 9,2 2,185 C21orf6 6 nucleoporin 1048 0,0016925 0,088241 126,3 57,8 2,185 NUP210 210kDa

histone cluster 1962 0,0046967 0,1308328 38,9 17,8 2,185 HIST1H2BH 1, H2bh beta 1,3- galactosyltrans 142 0,0001159 0,0439272 166 76,1 2,181 B3GALTL ferase-like

ependymin related protein 4061 0,0168405 0,2266524 60,4 27,7 2,181 EPDR1 1 (zebrafish) disabled homolog 2, mitogen- responsive phosphoprotei 1669 0,0035837 0,1173989 180,1 82,6 2,18 DAB2 n (Drosophila)

solute carrier family 30 (zinc transporter), 291 0,0002854 0,0532207 293,2 134,6 2,178 SLC30A5 member 5 ring finger protein 170 /// ring finger 589 0,0007117 0,0657513 116,5 53,5 2,178 RNF170 protein 170

996 0,0015632 0,0858112 1005,8 461,8 2,178 FBXO9 F-box protein 9

coiled-coil- helix-coiled-coil- helix domain 241 0,0002235 0,0507048 671,7 308,6 2,177 CHCHD7 containing 7 hypothetical protein 491 0,0005617 0,0624087 104,3 47,9 2,177 FLJ23861 FLJ23861 erythrocyte membrane protein band 3161 0,0110094 0,1904267 45,7 21 2,176 EPB41L1 4.1-like 1 mitochondrial intermediate 1069 0,0017672 0,0903205 90,9 41,8 2,175 MIPEP peptidase

SEC11 homolog C (S. 681 0,0008774 0,0701954 274,8 126,4 2,174 SEC11C cerevisiae) DKFZP564C DKFZP564C15 2989 0,0099531 0,1820628 61,7 28,4 2,173 152 2 protein CDNA FLJ40891 fis, clone UTERU200111 2408 0,0068344 0,1551789 17,8 8,2 2,171 NA 0 2859 0,0092222 0,176217 53,6 24,7 2,17 10-sept septin 10 ubiquitin specific 6781 0,041544 0,3349474 29,7 13,7 2,168 USP2 peptidase 2 hypothetical protein 39 2,44E-05 0,0312927 652,1 301,1 2,166 FLJ20186 FLJ20186

transmembran 709 0,000918 0,0707922 147,1 67,9 2,166 TMEM144 e protein 144 RAD50 homolog (S. 3431 0,0125349 0,1997008 101,8 47 2,166 RAD50 cerevisiae) fumarate 1487 0,0029822 0,1095772 74,7 34,5 2,165 FH hydratase 37 2,30E-05 0,0312927 14,5 6,7 2,164 MYO6 myosin VI chromosome 10 open reading frame 654 0,0008268 0,0691212 699,1 323,6 2,16 C10orf22 22 hypothetical protein 239 0,0002213 0,0506258 252,6 117 2,159 FLJ38482 FLJ38482

tumor necrosis factor (ligand) superfamily, member 13 /// tumor necrosis factor (ligand) TNFSF13 /// superfamily, TNFSF12- member 12- 3254 0,011531 0,1936505 408,4 189,2 2,159 TNFSF13 member 13

Full-length cDNA clone CS0DE011YO 20 of Placenta of Homo sapiens 855 0,0012427 0,0791194 60 27,8 2,158 NA (human) molybdenum cofactor 1474 0,0029583 0,109553 87,2 40,4 2,158 MOCS2 synthesis 2 intersectin 1 (SH3 domain 5234 0,026366 0,2754224 41,4 19,2 2,156 ITSN1 protein) Transcribed 155 0,0001274 0,0449393 48,7 22,6 2,155 NA locus tripartite motif- 3636 0,013658 0,2052986 107,1 49,7 2,155 TRIM13 containing 13 Transcribed 648 0,0008158 0,0687608 580,4 269,4 2,154 NA locus B-cell CLL/lymphoma 11A (zinc finger 2507 0,0073267 0,1597875 70 32,5 2,154 BCL11A protein) Heat shock 70kDa protein 4743 0,0221419 0,2552411 98 45,5 2,154 HSPA4 4 chloride 616 0,0007421 0,0657513 264,4 122,8 2,153 CLCN3 channel 3 abhydrolase domain 554 0,0006487 0,0640211 295,7 137,4 2,152 ABHD10 containing 10 Protein kinase 4813 0,0227026 0,257834 303,7 141,1 2,152 PRKCB1 C, beta 1 ATP-binding cassette, sub- family B (MDR/TAP), 136 0,0001073 0,043137 156,6 72,8 2,151 ABCB10 member 10 syntaxin binding protein 6485 0,038175 0,3218532 68,2 31,7 2,151 STXBP1 1 666 0,0008507 0,0697147 140,4 65,3 2,15 SFXN4 sideroflexin 4 WD repeat 5184 0,0259104 0,2732737 114,7 53,4 2,148 WDR4 domain 4 hypothetical protein 3131 0,010797 0,1885423 267,5 124,6 2,147 MGC16169 MGC16169 Protein kinase 3155 0,0109875 0,1904094 268,4 125 2,147 PRKCB1 C, beta 1 protein tyrosine phosphatase, receptor type, O /// protein tyrosine phosphatase, receptor type, 4207 0,0179193 0,2327543 430,4 200,5 2,147 PTPRO O testis specific, 6434 0,0376858 0,3201776 20,4 9,5 2,147 TSGA14 14 acyl- Coenzyme A dehydrogenas e, C-4 to C-12 828 0,0011809 0,0779779 507,2 236,4 2,146 ACADM straight chain

histone cluster 4287 0,0185372 0,2364174 127,4 59,4 2,145 HIST1H2BD 1, H2bd phosphatidylin ositol glycan anchor biosynthesis, 2236 0,0059362 0,1451528 41,8 19,5 2,144 PIGM class M

Cbl-interacting 1539 0,0031941 0,1132377 145,7 68 2,143 STS-1 protein Sts-1 hypothetical protein 3754 0,0143698 0,2092884 19,5 9,1 2,143 LOC203274 LOC203274

four and a half 2579 0,0077984 0,1652859 51,2 23,9 2,142 FHL1 LIM domains 1 RAB42, member RAS oncogene 1183 0,0020847 0,0961653 256,1 119,6 2,141 RAB42 family ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3- 919 0,0013698 0,0814182 2276 1063,4 2,14 ELOVL5 like, yeast) heterogeneous nuclear ribonucleoprot 1789 0,0040289 0,1230921 36,6 17,1 2,14 HNRPLL ein L-like Hypothetical protein 4984 0,0241657 0,2650734 431,5 201,6 2,14 LOC221710 LOC221710

536 0,0006295 0,0635709 25 11,7 2,137 CD72 CD72 molecule Src-like- 6415 0,0374978 0,3195327 18,8 8,8 2,136 SLA adaptor family with sequence similarity 82, 2352 0,0065321 0,1518463 122,1 57,2 2,135 FAM82A member A protein tyrosine phosphatase, non-receptor type 22 6031 0,0336768 0,3052384 107,2 50,2 2,135 PTPN22 (lymphoid) 1738 0,0038175 0,1200931 58,9 27,6 2,134 KIAA1632 KIAA1632

MRNA; cDNA DKFZp762M12 7 (from clone DKFZp762M12 330 0,0003373 0,0552439 317,1 148,7 2,132 NA 7) KIAA0143 257 0,0002459 0,0521767 934,5 438,6 2,131 KIAA0143 protein ST6 beta- galactosamide alpha-2,6- sialyltranferase 2181 0,0056885 0,1426037 29,6 13,9 2,129 ST6GAL1 1

suppression of tumorigenicity 328 0,000336 0,0552439 154 72,4 2,127 ST7 7 WD repeat 388 0,0004119 0,0577756 222,7 104,7 2,127 WDR68 domain 68 epidermal growth factor receptor pathway 460 0,0005057 0,0600239 335,3 157,8 2,125 EPS8 substrate 8 F-box protein 9 /// chromosome 20 open FBXO9 /// reading frame 565 0,0006637 0,064104 597,7 281,3 2,125 C20orf44 44 solute carrier family 20 (phosphate transporter), 1043 0,0016853 0,088241 18,7 8,8 2,125 SLC20A2 member 2

steroid 5 alpha- reductase 2- 4337 0,0189089 0,2383777 13,6 6,4 2,125 SRD5A2L like lactate dehydrogenas 432 0,0004566 0,0577884 1726,6 812,9 2,124 LDHB e B Transmembran 856 0,001247 0,0791194 95,6 45 2,124 TMEM53 e protein 53 Cornichon homolog 4 1453 0,0028741 0,1081496 94,7 44,6 2,123 CNIH4 (Drosophila) Ubiquitin specific 2404 0,0067949 0,15452 79,6 37,5 2,123 USP30 peptidase 30 CDNA FLJ34013 fis, clone FCBBF200211 1279 0,0023564 0,100732 1276,3 601,6 2,122 NA 1 ribulose-5- phosphate-3- 68 4,48E-05 0,0355773 181,7 85,7 2,12 RPE epimerase mitochondrial tumor 2060 0,005159 0,1368599 22,9 10,8 2,12 MTUS1 suppressor 1

MRNA; cDNA DKFZp434N02 20 (from clone DKFZp434N02 4317 0,0187246 0,2370955 56,6 26,7 2,12 NA 20) nucleoporin 2747 0,0086591 0,1723467 75,6 35,7 2,118 NUP160 160kDa

TIMP metallopeptida se inhibitor 3 (Sorsby fundus dystrophy, pseudoinflamm 2804 0,008981 0,1750515 207,8 98,1 2,118 TIMP3 atory)

MRNA; cDNA DKFZp779F23 45 (from clone DKFZp779F23 4730 0,0220372 0,2547323 27,1 12,8 2,117 NA 45)

sphingosine-1- phosphate phosphatase 1 /// sphingosine- 1-phosphate 19 1,37E-05 0,0302321 109,8 51,9 2,116 SGPP1 phosphatase 1

small nuclear RNA activating complex, polypeptide 3, 2089 0,0052902 0,1384594 87,6 41,4 2,116 SNAPC3 50kDa phenylalanine- tRNA synthetase- like, alpha 342 0,0003474 0,0552439 253,2 119,7 2,115 FARSLA subunit Chromodomai n helicase DNA binding protein 2506 0,0073221 0,1597509 29,6 14 2,114 CHD9 9 SPFH domain family, member 49 3,02E-05 0,0326978 155,5 73,6 2,113 SPFH2 2 GA binding protein transcription factor, beta 2676 0,0082757 0,1690677 39,3 18,6 2,113 GABPB2 subunit 2

chromosome 5 open reading 5032 0,0245722 0,2669883 30 14,2 2,113 C5orf28 frame 28

FK506 binding protein 1A, 521 0,0006075 0,0635709 544,5 257,8 2,112 FKBP1A 12kDa 2627 0,0080638 0,167497 492,4 233,1 2,112 11-sept septin 11

IKK interacting 7313 0,0472315 0,3531221 71,6 33,9 2,112 IKIP protein solute carrier family 4, sodium bicarbonate cotransporter, 623 0,000756 0,0663472 11,4 5,4 2,111 SLC4A7 member 7

chromosome 4 open reading 2267 0,00611 0,1473596 556,8 263,7 2,111 C4orf18 frame 18 Full-length cDNA clone CS0DF032YA1 1 of Fetal brain of Homo sapiens 483 0,0005452 0,0615795 27,2 12,9 2,109 NA (human) glycine cleavage system protein H (aminomethyl carrier) /// similar to Glycine cleavage system H protein, GCSH /// mitochondrial 1815 0,0041249 0,1241646 218,5 103,6 2,109 LOC730107 precursor anaphase promoting complex 1013 0,0016054 0,0866252 46,8 22,2 2,108 ANAPC7 subunit 7

chromosome 1 open reading 4467 0,0199512 0,244186 77,8 36,9 2,108 C1orf25 frame 25 carbamoyl- phosphate synthetase 2, aspartate transcarbamyla se, and dihydroorotase /// Rho guanine nucleotide exchange CAD /// factor (GEF) 5 ARHGEF5 /// /// FLJ40722- 98 6,66E-05 0,0371567 82,6 39,2 2,107 LOC653691 like Rho-related BTB domain 1684 0,0036341 0,1177064 69,1 32,8 2,107 RHOBTB3 containing 3

chromosome 2 open reading 1777 0,0039818 0,1224818 99,4 47,2 2,106 C2orf43 frame 43 WD repeat 1249 0,0022551 0,0986109 34,1 16,2 2,105 WDR67 domain 67 solute carrier family 35, 3061 0,0104007 0,1857753 220,6 104,8 2,105 SLC35A5 member A5

progestin and adipoQ receptor family 5718 0,0306298 0,2928794 135,5 64,4 2,104 PAQR8 member VIII leukotriene B4 1994 0,0048487 0,1329502 65,2 31 2,103 LTB4R receptor G protein- coupled 5343 0,0273073 0,2793774 470,2 223,6 2,103 GPR65 receptor 65 CDNA clone IMAGE:482080 1746 0,0038565 0,1207641 152 72,3 2,102 NA 9 desmoglein 1 /// zinc finger, DSG1 /// H2C2 domain 706 0,0009094 0,070427 39,7 18,9 2,101 ZH2C2 containing caspase 3, apoptosis- related cysteine 263 0,0002521 0,0521767 338,9 161,5 2,098 CASP3 peptidase dicarbonyl/L- xylulose 405 0,0004332 0,0577884 413,4 197 2,098 DCXR reductase

MRNA; cDNA DKFZp762E13 14 (from clone DKFZp762E13 1379 0,0026469 0,1048471 382,2 182,2 2,098 NA 14) HEAT repeat 2209 0,0058268 0,1441488 192 91,5 2,098 HEATR3 containing 3 CDNA FLJ31107 fis, clone IMR32200015 4987 0,0241778 0,2650734 200,1 95,4 2,097 NA 2 ribulose-5- phosphate-3- 273 0,0002661 0,0525339 420,3 200,7 2,094 RPE epimerase Zinc finger 596 0,0007211 0,0657513 33,5 16 2,094 ZNF268 protein 268 ATP-binding cassette, sub- family G (WHITE), 2980 0,0098869 0,1813981 1054,5 503,6 2,094 ABCG2 member 2 early endosome antigen 1, 53 3,23E-05 0,0332026 475,1 227 2,093 EEA1 162kD ribulose-5- phosphate-3- 520 0,0006065 0,0635709 225,9 108 2,092 RPE epimerase

SNF2 histone linker PHD 2617 0,0080128 0,1673744 54,4 26 2,092 SHPRH RING helicase

tumor necrosis factor, alpha- induced 4932 0,0236838 0,2625531 334,2 159,8 2,091 TNFAIP8L2 protein 8-like 2

N- ethylmaleimide- 498 0,0005699 0,0625688 991,2 474,3 2,09 NSF sensitive factor guanine nucleotide binding protein (G protein), beta 732 0,0009636 0,0719738 201,3 96,3 2,09 GNB4 polypeptide 4 cleavage stimulation factor, 3@#$%& pre- RNA, subunit 2658 0,0082016 0,1686659 200 95,7 2,09 CSTF3 3, 77kDa

mutS homolog 2, colon cancer, nonpolyposis 7413 0,0482526 0,3558898 53,3 25,5 2,09 MSH2 type 1 (E. coli) BRCA1/BRCA 2-containing complex, 1042 0,0016843 0,088241 164,5 78,8 2,088 BRCC3 subunit 3 cofilin 2 468 0,0005159 0,0602236 43,4 20,8 2,087 CFL2 (muscle) ubiquitin- conjugating enzyme E2, J1 (UBC6 homolog, 1106 0,0018679 0,0923395 368,7 176,7 2,087 UBE2J1 yeast) disabled homolog 1 (Drosophila) /// OMA1 homolog, zinc metallopeptida DAB1 /// se (S. 2547 0,0075918 0,1628925 86,8 41,6 2,087 OMA1 cerevisiae) GLI pathogenesis- related 1 3212 0,0113503 0,193206 634,1 303,9 2,087 GLIPR1 (glioma) lactate dehydrogenas 383 0,0004066 0,0577756 2256,7 1082,6 2,085 LDHB e B 959 0,0014733 0,0839343 73,8 35,4 2,085 NA NA DPH3, KTI11 homolog (S. 283 0,0002742 0,0525339 221,3 106,2 2,084 DPH3 cerevisiae) proprotein convertase subtilisin/kexin 2024 0,0050108 0,1353584 65,4 31,4 2,083 PCSK5 type 5 zinc finger protein 627 /// zinc finger 3808 0,0148599 0,2133574 62,5 30 2,083 ZNF627 protein 627 Zinc finger 6463 0,0379088 0,3206968 15 7,2 2,083 ZNF117 protein 117

peroxisome proliferator- activated 170 0,0001467 0,0471813 61,2 29,4 2,082 PPARA receptor alpha solute carrier family 9 (sodium/hydro gen exchanger), 2219 0,0058548 0,1441488 55,8 26,8 2,082 SLC9A7 member 7 TPTE 6275 0,0362215 0,3156033 25,8 12,4 2,081 psiTPTE22 pseudogene Rho GTPase activating 36 2,12E-05 0,0312927 76,5 36,8 2,079 ARHGAP12 protein 12 67 4,46E-05 0,0355773 1017,3 489,4 2,079 KIAA0274 KIAA0274

glycerol-3- phosphate acyltransferase 1225 0,0021957 0,0979999 37 17,8 2,079 GPAM , mitochondrial solute carrier family 25, 934 0,0014113 0,082425 77,1 37,1 2,078 SLC25A35 member 35 nucleoporin 1587 0,0033286 0,1146762 208,8 100,5 2,078 NUP210 210kDa dihydrofolate reductase-like 2835 0,0090983 0,1754434 26,6 12,8 2,078 DHFRL1 1 early endosome antigen 1, 912 0,0013515 0,0810038 37,8 18,2 2,077 EEA1 162kD

Solute carrier family 30 (zinc transporter), 1856 0,0042804 0,126041 1278 615,4 2,077 SLC30A1 member 1 hypothetical protein 755 0,0010126 0,0733297 251 120,9 2,076 LOC162073 LOC162073 hydroxyacyl- Coenzyme A dehydrogenas e/3-ketoacyl- Coenzyme A thiolase/enoyl- Coenzyme A hydratase (trifunctional protein), alpha 1768 0,0039428 0,1219045 2199,1 1059,2 2,076 HADHA subunit Insulin-like growth factor 2 489 0,0005602 0,0624087 28 13,5 2,074 IGF2R receptor S- adenosylhomo cysteine 1357 0,002586 0,1040748 535,1 258 2,074 AHCY hydrolase aminolevulinat e, delta-, 6694 0,040477 0,3305765 1440,8 694,8 2,074 ALAS1 synthase 1 LIM domain 287 0,0002761 0,0525487 53,9 26 2,073 LIMK1 kinase 1 RAS guanyl releasing protein 1 (calcium and DAG- 4865 0,0231461 0,2599793 19,9 9,6 2,073 RASGRP1 regulated) potassium inwardly- rectifying channel, subfamily J, 6696 0,0404931 0,3305765 22,8 11 2,073 KCNJ1 member 1 Toll-like 5029 0,0245594 0,2669883 100,3 48,4 2,072 TLR1 receptor 1 RAD51 associated 995 0,001563 0,0858112 32,1 15,5 2,071 RAD51AP1 protein 1 protein tyrosine phosphatase- like A domain containing 1 /// similar to butyrate- PTPLAD1 /// induced 839 0,0012144 0,0790355 163,3 78,9 2,07 LOC732402 transcript 1 Rab9 effector protein with 4753 0,0222357 0,2557831 198,3 95,8 2,07 RABEPK kelch motifs Transcribed 3096 0,0106234 0,1874018 54 26,1 2,069 NA locus SMAD family 3313 0,0118943 0,1962936 104,3 50,4 2,069 SMAD1 member 1 phospholipase D1, phosphatidylch 1607 0,0034046 0,1157798 15,3 7,4 2,068 PLD1 oline-specific aconitase 1, soluble /// ACO1 /// ankyrin repeat 2760 0,0087336 0,1730107 186,3 90,1 2,068 ANKRD15 domain 15

fibronectin type III domain 7235 0,0463715 0,350421 127,8 61,8 2,068 FNDC3B containing 3B CDNA FLJ37302 fis, clone BRAMY20160 3564 0,0132786 0,2036605 207,3 100,3 2,067 NA 09 chromosome 14 open reading frame 3956 0,0159818 0,2208555 174 84,2 2,067 C14orf142 142 PDZ and LIM 278 0,0002689 0,0525339 568,9 275,3 2,066 PDLIM5 domain 5 staufen, RNA binding protein, homolog 2 827 0,0011785 0,0779135 53,1 25,7 2,066 STAU2 (Drosophila) ATPase, H+ transporting, lysosomal V0 301 0,000296 0,0537668 144,9 70,2 2,064 ATP6V0A2 subunit a2 CDNA FLJ35131 fis, clone PLACE600882 1704 0,0037034 0,1188067 81,1 39,3 2,064 NA 4 3969 0,016084 0,2215653 61,5 29,8 2,064 NA NA F-box protein 344 0,0003483 0,0552439 110,6 53,6 2,063 FBXO22 22

1347 0,0025575 0,1036037 121,9 59,1 2,063 CD84 CD84 molecule arylacetamide deacetylase- 5904 0,0323489 0,2995725 851,5 412,8 2,063 AADACL1 like 1 dyslexia susceptibility 1 745 0,0009951 0,0729195 13,2 6,4 2,062 DYX1C1 candidate 1 short coiled- 166 0,0001412 0,0465067 137,9 66,9 2,061 SCOC coil protein hypothetical protein 203 0,000182 0,0483249 170,2 82,6 2,061 FLJ21908 FLJ21908 spermidine 1340 0,0025484 0,1036037 228,8 111 2,061 SRM synthase cleavage and polyadenylatio n specific factor 2, 2171 0,0056329 0,1417702 143,6 69,7 2,06 CPSF2 100kDa Heterogeneou s nuclear ribonucleoprot 1245 0,002246 0,0986109 49,2 23,9 2,059 HNRPLL ein L-like phosphatidylin ositol 4-kinase 5865 0,0318826 0,2972176 224,4 109 2,059 PI4KII type II zinc finger, FYVE domain 22 1,47E-05 0,0302321 265,5 129 2,058 ZFYVE26 containing 26 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, 928 0,0013999 0,0824182 18,3 8,9 2,056 ALS2CR8 candidate 8 1072 0,0017717 0,0903205 1084,8 527,6 2,056 SORT1 sortilin 1 SLIT-ROBO Rho GTPase activating 1374 0,0026394 0,1048471 110,4 53,7 2,056 SRGAP1 protein 1 hydroxyacyl- Coenzyme A dehydrogenas 415 0,0004428 0,0577884 222,8 108,5 2,053 HADH e

sphingomyelin phosphodieste rase 1, acid lysosomal (acid sphingomyelin 509 0,0005863 0,0629783 136,3 66,4 2,053 SMPD1 ase)

chromosome 2 open reading 876 0,0012692 0,0792042 184,4 89,8 2,053 C2orf7 frame 7 chromosome 10 open reading frame 1537 0,0031873 0,1132377 93,8 45,7 2,053 C10orf6 6 Transcribed 3220 0,0113869 0,193258 23,4 11,4 2,053 NA locus transformation/ transcription domain- associated 558 0,000656 0,064104 74,3 36,2 2,052 TRRAP protein

chaperone, ABC1 activity of bc1 complex homolog (S. 4715 0,0219434 0,2543476 290,8 141,8 2,051 CABC1 pombe) zinc binding alcohol dehydrogenas e, domain 4796 0,0226174 0,257834 65,2 31,8 2,05 ZADH2 containing 2 ets homologous 132 0,0001058 0,0431325 37,3 18,2 2,049 EHF factor membrane bound O- acyltransferase domain 1933 0,0045795 0,1294851 151 73,7 2,049 MBOAT1 containing 1 hypothetical protein 2178 0,0056659 0,1422328 12,5 6,1 2,049 FLJ11184 FLJ11184

chromosome 5 open reading 452 0,0004934 0,0596828 123,3 60,2 2,048 C5orf28 frame 28 methylcrotonoy l-Coenzyme A carboxylase 2 362 0,0003764 0,0568499 322,5 157,6 2,046 MCCC2 (beta) nicotinamide nucleotide adenylyltransfe 3700 0,0140668 0,2077812 80 39,1 2,046 NMNAT1 rase 1

Fukuyama type congenital muscular dystrophy 3572 0,0133241 0,203946 22,9 11,2 2,045 FCMD (fukutin) kelch-like 8 94 6,37E-05 0,0367348 263,7 129,1 2,043 KLHL8 (Drosophila) tumor protein p53 inducible 3684 0,0139504 0,2070407 146,3 71,6 2,043 TP53I3 protein 3 MDN1, midasin homolog 804 0,001118 0,0760282 63,3 31 2,042 MDN1 (yeast)

coiled-coil- helix-coiled-coil- helix domain 75 4,99E-05 0,0357118 139,4 68,3 2,041 CHCHD4 containing 4 apoptosis- inducing factor, mitochondrion- 1005 0,0015861 0,0862245 299,2 146,7 2,04 AIFM1 associated, 1

chromosome 1 open reading 2452 0,0070518 0,1572068 87,3 42,8 2,04 C1orf79 frame 79 Proteasome (prosome, macropain) subunit, beta 1065 0,0017592 0,0902138 378,6 185,7 2,039 PSMB7 type, 7 cytokine inducible SH2- containing 7546 0,0496666 0,3598523 613,4 300,9 2,039 CISH protein hydroxyacyl- Coenzyme A dehydrogenas e/3-ketoacyl- Coenzyme A thiolase/enoyl- Coenzyme A hydratase (trifunctional protein), alpha 3554 0,0131961 0,2030098 2155,2 1057,6 2,038 HADHA subunit 6674 0,0402214 0,3295033 69,1 33,9 2,038 PLXNC1 plexin C1 Keratin associated 1568 0,0032684 0,1138946 918,9 451 2,037 KRTAP4-7 protein 4-7 Bardet-Biedl 3342 0,0120795 0,1975742 88,6 43,5 2,037 BBS2 syndrome 2 zinc finger 4921 0,0235974 0,26218 57 28 2,036 ZNF226 protein 226 Vesicle docking protein 7358 0,0477357 0,3546795 33,8 16,6 2,036 VDP p115 F-box protein 1897 0,0044723 0,1288998 51,7 25,4 2,035 FBXO31 31

ST6 (alpha-N- acetyl- neuraminyl-2,3- beta-galactosyl- 1,3)-N- acetylgalactos aminide alpha- 2,6- ST6GALNA sialyltransferas 3053 0,0103581 0,1854868 116,8 57,4 2,035 C4 e 4 STEAP family 1160 0,0020201 0,0952146 18,1 8,9 2,034 STEAP3 member 3 2458 0,0070676 0,1572095 270,7 133,1 2,034 GLS glutaminase tigger transposable element 6083 0,0341759 0,3071786 53,3 26,2 2,034 TIGD2 derived 2 abhydrolase domain 7090 0,0447282 0,3448586 188,1 92,5 2,034 ABHD2 containing 2 lactamase, 219 0,0001958 0,0483249 383,5 188,6 2,033 LACTB2 beta 2 Spermidine/sp ermine N1- acetyl transferase-like 433 0,0004639 0,0583909 116,9 57,5 2,033 SATL1 1 Keratin associated 1852 0,0042692 0,1259529 160,4 78,9 2,033 KRTAP4-7 protein 4-7 protein kinase 2616 0,0080107 0,1673744 415,4 204,3 2,033 PRKCB1 C, beta 1 WD repeat 2155 0,0055779 0,1413783 220,7 108,6 2,032 WDR1 domain 1 UDP- glucuronate decarboxylase 4297 0,0186159 0,2368636 226,4 111,4 2,032 UXS1 1 prenylcysteine 4890 0,0233636 0,261228 51,8 25,5 2,031 PCYOX1 oxidase 1 6- phosphofructo- 2- kinase/fructose- 2,6- biphosphatase 1294 0,0024201 0,1022034 27,4 13,5 2,03 PFKFB2 2 phosphodieste 2542 0,0075727 0,1628516 359,6 177,1 2,03 PDE8A rase 8A

FK506 binding protein 15, 3236 0,0114544 0,1934716 73,9 36,4 2,03 FKBP15 133kDa myotubularin related protein 1312 0,0024762 0,1029968 63,5 31,3 2,029 MTMR2 2

Phosphoribosy lglycinamide formyltransfera se, phosphoribosyl glycinamide synthetase, phosphoribosyl aminoimidazol 2084 0,0052717 0,1383062 14,2 7 2,029 GART e synthetase Transcribed 6875 0,0423635 0,3368398 750,5 370 2,028 NA locus PDZ and LIM 1998 0,0048739 0,1333736 499,3 246,5 2,026 PDLIM5 domain 5

Transmembran 2008 0,0049058 0,133578 122,4 60,4 2,026 TMEM165 e protein 165 Interleukin 17 3372 0,012234 0,1983671 47 23,2 2,026 IL17RB receptor B aldehyde dehydrogenas e 1 family, 2697 0,0083684 0,1695229 212,5 105 2,024 ALDH1A1 member A1 Full-length cDNA clone CS0DE011YO 20 of Placenta of Homo sapiens 2612 0,0079818 0,167036 256,1 126,6 2,023 NA (human) prostaglandin D2 synthase, 3530 0,0130829 0,2025512 26,9 13,3 2,023 PGDS hematopoietic eukaryotic translation initiation factor 1410 0,002744 0,1063878 232 114,8 2,021 EIF2C1 2C, 1 WD repeat 270 0,0002638 0,0525339 267,9 132,6 2,02 WDR12 domain 12 solute carrier family 9 (sodium/hydro gen exchanger), 1376 0,0026423 0,1048471 20,6 10,2 2,02 SLC9A7 member 7

Homo sapiens, clone IMAGE:33529 951 0,0014435 0,0829899 62,6 31 2,019 NA 13, mRNA Sorting nexin associated 1993 0,0048474 0,1329502 511,5 253,4 2,019 SNAG1 golgi protein 1 SPFH domain family, member 326 0,0003293 0,0552285 44,2 21,9 2,018 SPFH2 2 Iron- responsive element binding protein 1027 0,0016561 0,0879972 312,6 154,9 2,018 IREB2 2 dihydrolipoami de S- acetyltransfera se (E2 component of pyruvate dehydrogenas 2137 0,0054923 0,1404697 125,7 62,3 2,018 DLAT e complex) guanylate cyclase activator 1A 3498 0,0129418 0,2021636 44,6 22,1 2,018 GUCA1A (retina) proline synthetase co- transcribed homolog 4756 0,0222681 0,2559942 147,1 72,9 2,018 PROSC (bacterial)

ATPase, Class 213 0,0001911 0,0483249 423 209,7 2,017 ATP9B II, type 9B family with sequence similarity 20, 2877 0,0092882 0,1764798 968,3 480 2,017 FAM20C member C TBC1 domain family, member 8 (with GRAM 2943 0,0096802 0,1796896 651,8 323,1 2,017 TBC1D8 domain) YKT6 v- SNARE homolog (S. 7135 0,0452156 0,3464592 96,2 47,7 2,017 YKT6 cerevisiae) adenosine deaminase, tRNA-specific 633 0,0007728 0,0666535 61,4 30,5 2,013 ADAT1 1 CD22 molecule /// myelin CD22 /// associated 1690 0,0036411 0,1177064 16,1 8 2,013 MAG glycoprotein dihydrolipoami de branched chain transacylase 1805 0,0040888 0,1238059 17,3 8,6 2,012 DBT E2 receptor accessory 984 0,0015357 0,0853041 18,1 9 2,011 REEP3 protein 3 pericentriolar 2053 0,0051368 0,136802 71,4 35,5 2,011 PCM1 material 1

570 0,0006683 0,064104 118,8 59,1 2,01 CD84 CD84 molecule mindbomb homolog 1 6127 0,0347288 0,309864 97,1 48,3 2,01 MIB1 (Drosophila) CKLF-like MARVEL transmembran e domain 3706 0,0140937 0,2079258 129,2 64,3 2,009 CMTM7 containing 7 necdin homolog 4678 0,0216763 0,253301 44 21,9 2,009 NDN (mouse) Hypothetical protein 2108 0,0053707 0,1392684 53,2 26,5 2,008 FLJ14959 FLJ14959 phosphatidylin ositol glycan anchor biosynthesis, 831 0,0011966 0,0786101 276,6 137,9 2,006 PIGG class G lupus brain 4105 0,0171666 0,2285213 34,7 17,3 2,006 LBA1 antigen 1 PML-RARA regulated adaptor 475 0,0005293 0,0609252 463,6 231,2 2,005 PRAM1 molecule 1 nicotinamide nucleotide transhydrogen 1382 0,0026519 0,1048471 337,8 168,5 2,005 NNT ase CDNA clone IMAGE:479188 7 /// MRNA; cDNA DKFZp564C07 62 (from clone DKFZp564C07 3475 0,0127289 0,2002741 41,3 20,6 2,005 NA 62) ubiquitin associated 3635 0,0136556 0,2052986 82,6 41,2 2,005 UBAP2L protein 2-like 4087 0,0170348 0,2277978 36,7 18,3 2,005 NA NA sterol O- acyltransferase (acyl- Coenzyme A: cholesterol acyltransferase 4184 0,0177239 0,2316095 1229,9 613,5 2,005 SOAT1 ) 1 solute carrier family 35, 271 0,0002653 0,0525339 229,1 114,3 2,004 SLC35B4 member B4 carnitine palmitoyltransf 164 0,0001373 0,0457736 186,1 92,9 2,003 CPT2 erase II ribulose-5- phosphate-3- epimerase /// similar to Ribulose- phosphate 3- epimerase (Ribulose-5- phosphate-3- epimerase) (HUSSY-17) /// similar to Ribulose- phosphate 3- RPE /// epimerase LOC649755 (Ribulose-5- /// phosphate-3- 542 0,0006318 0,0635709 78,9 39,4 2,003 LOC729020 epimerase) NIPA-like domain 740 0,0009765 0,0721488 59,3 29,6 2,003 NPAL2 containing 2

fibronectin type III domain 5252 0,0265069 0,2759453 366 182,7 2,003 FNDC3B containing 3B Transcribed 92 6,25E-05 0,0367348 68,2 34,1 2 NA locus

GUF1 GTPase homolog (S. 504 0,0005798 0,0628117 39,4 19,7 2 GUF1 cerevisiae) ets homologous 662 0,00084 0,0693761 28,8 14,4 2 EHF factor chromosome 1 open reading 2780 0,0088108 0,1732843 22 11 2 C1orf96 frame 96 Transcribed 6739 0,0410788 0,3332814 15,6 7,8 2 NA locus hypothetical protein 359 0,0003681 0,0560609 80,1 40,1 1,998 P15RS FLJ10656 protein tyrosine phosphatase, non-receptor 4968 0,0239935 0,2640168 450,2 225,3 1,998 PTPN7 type 7 chromosome 20 open reading frame 38 2,41E-05 0,0312927 272,6 136,5 1,997 C20orf72 72 zinc metallopeptida se (STE24 homolog, 1140 0,001976 0,0946254 533,4 267,2 1,996 ZMPSTE24 yeast) ring finger 2339 0,0064289 0,1502779 163,7 82 1,996 RNF14 protein 14 thioredoxin domain containing 5 /// thioredoxin domain 169 0,0001465 0,0471813 694 347,9 1,995 TXNDC5 containing 5 transferrin receptor (p90, CD71) /// transferrin receptor (p90, 2878 0,0092896 0,1764798 5422,9 2718,5 1,995 TFRC CD71)

FUN14 domain 3545 0,0131491 0,2028003 158,1 79,3 1,994 FUNDC1 containing 1 2216 0,0058475 0,1441488 376,3 188,8 1,993 KIAA0152 KIAA0152 Zyg-11 homolog B (C. 1045 0,0016909 0,088241 264,1 132,6 1,992 ZYG11B elegans) insulin-like growth factor 2 1518 0,0030942 0,1113787 889,6 446,6 1,992 IGF2R receptor 1680 0,0036213 0,1177064 71,1 35,7 1,992 SFXN4 sideroflexin 4 CDNA FLJ38461 fis, clone FEBRA202097 4001 0,0163976 0,2240719 24,9 12,5 1,992 NA 7 centrin, EF- hand protein, 3 (CDC31 homolog, 5485 0,0285506 0,2845951 165,5 83,1 1,992 CETN3 yeast) ATPase, H+ transporting, lysosomal 42kDa, V1 439 0,0004718 0,0586671 231,6 116,4 1,99 ATP6V1C1 subunit C1 dedicator of 137 0,0001088 0,0434207 226,1 113,7 1,989 DOCK7 cytokinesis 7 solute carrier family 2 (facilitated glucose transporter), 289 0,0002837 0,0532207 54,3 27,3 1,989 SLC2A13 member 13 3175 0,0111391 0,1918206 37,4 18,8 1,989 HOXA1 homeobox A1 Synaptotagmin 5664 0,0301556 0,2910113 88,5 44,5 1,989 SYT17 XVII

G elongation factor, 1198 0,0021267 0,0970402 67 33,7 1,988 GFM1 mitochondrial 1 SATB family 2205 0,0058069 0,1439874 17,1 8,6 1,988 SATB2 member 2

reticulocalbin 2, EF-hand calcium 692 0,0008954 0,070427 139,5 70,2 1,987 RCN2 binding domain tetratricopeptid e repeat 1529 0,0031332 0,1120337 330,3 166,2 1,987 TTC9C domain 9C chloride channel 5 (nephrolithiasis 2, X-linked, 1596 0,0033671 0,1153485 69,9 35,2 1,986 CLCN5 Dent disease) 1965 0,004707 0,1309696 96,7 48,7 1,986 LOC116143 monad chromosome 20 open reading frame 366 0,000385 0,0575133 13,3 6,7 1,985 C20orf133 133 929 0,0014016 0,0824182 40,1 20,2 1,985 NA NA

3187 0,0111996 0,1921 134 67,5 1,985 ARSB arylsulfatase B solute carrier family 24 (sodium/potass ium/calcium exchanger), 853 0,0012382 0,0791194 71,8 36,2 1,983 SLC24A1 member 1 component of oligomeric golgi complex 981 0,0015222 0,0848382 133 67,1 1,982 COG6 6

Carbohydrate (chondroitin 4) sulfotransferas 708 0,0009172 0,0707922 1090,4 550,3 1,981 CHST11 e 11 diazepam binding inhibitor (GABA receptor modulator, acyl- Coenzyme A binding protein) /// diazepam binding inhibitor (GABA receptor modulator, acyl- Coenzyme A binding 1508 0,0030671 0,1110329 3598 1816,7 1,981 DBI protein) pterin-4 alpha- carbinolamine dehydratase/di merization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 390 0,000413 0,0577756 70,9 35,8 1,98 PCBD2 2

NADH dehydrogenas e (ubiquinone) Fe-S protein 8, 23kDa (NADH- coenzyme Q 1719 0,0037616 0,1195727 292,8 147,9 1,98 NDUFS8 reductase) Kynurenine RP11- aminotransfera 2480 0,0072084 0,1589191 28,7 14,5 1,979 82K18.3 se III phosphatidylin ositol glycan anchor biosynthesis, 4220 0,0180168 0,2334286 72 36,4 1,978 PIGN class N acyl- Coenzyme A oxidase 1, 182 0,0001627 0,0481428 290,6 147 1,977 ACOX1 palmitoyl

oxysterol binding protein- like 1A /// oxysterol binding protein- 479 0,0005382 0,0614323 598,4 302,8 1,976 OSBPL1A like 1A WD repeat 1039 0,0016767 0,0881582 250,2 126,6 1,976 WDR68 domain 68

1894 0,0044622 0,128789 811,8 410,9 1,976 FBXO9 F-box protein 9 vacuolar protein sorting 24 homolog (S. 739 0,0009737 0,0720393 314 159 1,975 VPS24 cerevisiae)

peroxisome proliferator- activated 1344 0,0025542 0,1036037 40,3 20,4 1,975 PPARA receptor alpha

rabaptin, RAB GTPase binding effector 2074 0,0052219 0,1376603 318,8 161,5 1,974 RABEP1 protein 1 fucose-1- phosphate guanylyltransfe 3976 0,0161511 0,2220979 67,7 34,3 1,974 FPGT rase phosphoinositi de-3-kinase, catalytic, gamma 4628 0,021253 0,2510149 107,2 54,3 1,974 PIK3CG polypeptide major histocompatibili ty complex, 95 6,41E-05 0,0367348 170,1 86,2 1,973 MR1 class I-related Immunoglobuli n heavy constant alpha 197 0,0001786 0,0483249 81,9 41,5 1,973 IGHA1 1 histidine acid phosphatase domain 1258 0,0022747 0,0987873 339,7 172,2 1,973 HISPPD1 containing 1 programmed 341 0,0003467 0,0552439 90,3 45,8 1,972 PDCD11 cell death 11 transforming growth factor, 2618 0,0080181 0,1673744 383,5 194,5 1,972 TGFA alpha guanine nucleotide binding protein (G protein), beta 5518 0,0288784 0,2861279 181,5 92,1 1,971 GNB4 polypeptide 4 BCL2-like 11 (apoptosis 3695 0,0140187 0,2073717 467,4 237,2 1,97 BCL2L11 facilitator) PDLIM1 interacting 4150 0,0174727 0,2301972 39,4 20 1,97 PDIK1L kinase 1 like Nuclear factor of activated T- cells, cytoplasmic, calcineurin- 2199 0,0057742 0,1435306 49,8 25,3 1,968 NFATC2 dependent 2 4493 0,0201941 0,2457406 55,5 28,2 1,968 MFN2 mitofusin 2 A kinase (PRKA) anchor 6402 0,0373242 0,3187082 256,1 130,1 1,968 AKAP11 protein 11 lactamase, 57 3,75E-05 0,0353731 130,6 66,4 1,967 LACTB2 beta 2 sorting and assembly machinery component 50 homolog (S. 126 9,95E-05 0,0430138 513,2 260,9 1,967 SAMM50 cerevisiae)

Homo sapiens, Similar to LOC169932, clone IMAGE:44992 686 0,0008818 0,0701954 512,7 260,7 1,967 NA 03, mRNA

phosphoribosyl glycinamide formyltransfera se, phosphoribosyl glycinamide synthetase, phosphoribosyl aminoimidazol 1082 0,0017933 0,090618 137,1 69,7 1,967 GART e synthetase chromosome 10 open reading frame 58 /// chromosome 10 open reading frame 4556 0,0206652 0,247996 65,1 33,1 1,967 C10orf58 58 methylcrotonoy l-Coenzyme A carboxylase 2 892 0,0013039 0,0799223 40,5 20,6 1,966 MCCC2 (beta) DNA cross-link repair 1C (PSO2 homolog, S. 1407 0,0027334 0,1062179 29,3 14,9 1,966 DCLRE1C cerevisiae) 4494 0,0202177 0,2459038 174,4 88,7 1,966 NA NA SFRS protein 522 0,0006082 0,0635709 45 22,9 1,965 SRPK2 kinase 2 mannosidase, alpha, class 2460 0,0070767 0,157284 799,3 406,8 1,965 MAN2A1 2A, member 1 solute carrier family 25 (mitochondrial carrier; ornithine transporter) 162 0,0001364 0,0457736 44,2 22,5 1,964 SLC25A15 member 15

418 0,0004468 0,0577884 16,3 8,3 1,964 DNM1L Dynamin 1-like 2766 0,0087781 0,1732398 184,3 93,9 1,963 GK glycerol kinase low density lipoprotein receptor- related protein 3535 0,0131127 0,2025785 15,3 7,8 1,962 LRP11 11 4027 0,016609 0,2255021 51,6 26,3 1,962 MCOLN2 mucolipin 2 myotubularin related protein 3404 0,0123643 0,1984223 153,7 78,4 1,96 MTMR4 4 Transcribed 6248 0,0359563 0,3146464 39,2 20 1,96 NA locus

GLI-Kruppel family member GLI3 (Greig cephalopolysy ndactyly syndrome) /// 5@#$%&- nucleotidase GLI3 /// domain 1208 0,0021544 0,0974517 70,9 36,2 1,959 NT5DC1 containing 1 glycoprotein A33 (transmembran 6924 0,0429684 0,3392502 38,2 19,5 1,959 GPA33 e)

zinc finger and BTB domain 1315 0,0024827 0,1029968 47 24 1,958 ZBTB9 containing 9 peptidylprolyl isomerase (cyclophilin)- 2655 0,0081667 0,1681297 176,2 90 1,958 PPIL1 like 1 4118 0,0172447 0,2288456 18,6 9,5 1,958 MCOLN3 mucolipin 3 chromodomain helicase DNA binding protein 5381 0,0275853 0,2802874 51,1 26,1 1,958 CHD1L 1-like

6484 0,0381642 0,3218118 149,8 76,5 1,958 GK glycerol kinase chromodomain helicase DNA binding protein 127 0,0001006 0,0430138 169,1 86,4 1,957 CHD9 9

aspartate beta- 187 0,0001668 0,0481428 87,5 44,7 1,957 ASPH hydroxylase 3015 0,010109 0,1832002 44 22,5 1,956 IGHA1 NA

UTP14, U3 small nucleolar ribonucleoprot ein, homolog C 3711 0,0141241 0,2080936 165,3 84,5 1,956 UTP14C (yeast) FLJ43339 200 0,0001808 0,0483249 38,5 19,7 1,954 FLJ43339 protein Transcribed 572 0,0006754 0,0645586 126,4 64,7 1,954 NA locus abhydrolase domain 7067 0,0445022 0,3442985 307,1 157,2 1,954 ABHD6 containing 6 adenylate 810 0,0011323 0,0763495 94,9 48,6 1,953 AK1 kinase 1 abhydrolase domain 825 0,0011675 0,0773734 188,5 96,5 1,953 ABHD10 containing 10 prostaglandin- endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenas 6796 0,0417072 0,3354995 491,8 251,8 1,953 PTGS1 e) TNF receptor- associated 923 0,0013861 0,082042 232,5 119,2 1,951 TRAF5 factor 5 osteopetrosis associated transmembran 1006 0,0015865 0,0862245 325,5 166,8 1,951 OSTM1 e protein 1

chromosome 6 open reading 1085 0,0018019 0,0908008 775,8 397,6 1,951 C6orf115 frame 115 ethanolamine 5412 0,0279337 0,2822016 35,5 18,2 1,951 ETNK2 kinase 2

caspase recruitment domain family, 545 0,0006349 0,0635709 54,4 27,9 1,95 CARD14 member 14

p21/Cdc42/Ra c1-activated kinase 1 (STE20 homolog, yeast) /// PAK1 /// vesicle docking 1707 0,0037148 0,1189846 382,9 196,5 1,949 VDP protein p115 753 0,0010098 0,0732456 70,5 36,2 1,948 CTPS CTP synthase Transcribed 3245 0,0114877 0,1935562 485,9 249,6 1,947 NA locus

Ras-related 116 8,12E-05 0,0382725 336,6 173 1,946 RRAGD GTP binding D

MYC induced 1040 0,0016769 0,0881582 93,8 48,2 1,946 MINA nuclear antigen serine/threonin 1075 0,0017768 0,0903205 238,2 122,4 1,946 STK38 e kinase 38 proline-rich 1687 0,0036373 0,1177064 399,8 205,4 1,946 PRRC1 coiled-coil 1 Transcribed locus, strongly similar to XP_515434.1 hypothetical protein XP_515434 [Pan 1870 0,0043618 0,1275302 25,3 13 1,946 NA troglodytes]

ribosomal protein S6 kinase, 90kDa, 2863 0,0092312 0,176232 101 51,9 1,946 RPS6KA2 polypeptide 2 leukotriene B4 2299 0,0062621 0,1489258 59,7 30,7 1,945 LTB4R receptor pericentriolar 2995 0,0099969 0,1824977 42,4 21,8 1,945 PCM1 material 1

chromosome 4 open reading 1326 0,0025139 0,1035459 246,4 126,8 1,943 C4orf34 frame 34 abhydrolase domain 6243 0,0359207 0,3145866 286,1 147,3 1,942 ABHD6 containing 6 6477 0,0381048 0,3216112 60,2 31 1,942 RTN1 reticulon 1 PHD finger protein 20-like 2050 0,0051294 0,1367834 66 34 1,941 PHF20L1 1

tumor necrosis factor (ligand) superfamily, member 13 /// tumor necrosis factor (ligand) TNFSF13 /// superfamily, TNFSF12- member 12- 2630 0,0080694 0,167497 791,7 407,9 1,941 TNFSF13 member 13

chromosome 4 open reading 4900 0,0234647 0,2617508 26,4 13,6 1,941 C4orf29 frame 29

zinc finger and BTB domain 464 0,000512 0,0602236 65,2 33,6 1,94 ZBTB47 containing 47 Transcribed 916 0,0013571 0,0810038 26 13,4 1,94 NA locus

histone cluster 1017 0,0016113 0,0866252 100,9 52 1,94 HIST1H2BE 1, H2be transmembran 3654 0,0137532 0,2057899 259,7 133,9 1,94 TMEM33 e protein 33 family with sequence similarity 55, 6543 0,0386836 0,3232502 48,3 24,9 1,94 FAM55C member C anaphase promoting complex 76 5,00E-05 0,0357118 282 145,4 1,939 ANAPC7 subunit 7 osteopetrosis associated transmembran 202 0,0001817 0,0483249 130,5 67,3 1,939 OSTM1 e protein 1 beta 1,3- galactosyltrans 857 0,0012473 0,0791194 22,3 11,5 1,939 B3GALTL ferase-like 2-deoxyribose- 5-phosphate aldolase homolog (C. 512 0,0005907 0,0630791 525,1 271 1,938 DERA elegans) 5391 0,0276867 0,2807519 18,6 9,6 1,938 KIAA1212 KIAA1212

glycerol kinase /// glycerol kinase 3 7121 0,045073 0,3460577 84,9 43,8 1,938 GK /// GK3P pseudogene CDNA clone IMAGE:528482 4803 0,0226522 0,257834 30,8 15,9 1,937 NA 0 methyltransfer 122 9,05E-05 0,0405581 93,5 48,3 1,936 METTL8 ase like 8

ninein (GSK3B interacting 256 0,0002436 0,0520267 24,2 12,5 1,936 NIN protein)

diazepam binding inhibitor (GABA receptor modulator, acyl- Coenzyme A binding 1659 0,0035457 0,1168542 3678,6 1900 1,936 DBI protein) solute carrier family 33 (acetyl-CoA transporter), 1827 0,0041566 0,1242557 81,9 42,3 1,936 SLC33A1 member 1 CDNA: FLJ22627 fis, clone 3008 0,0100611 0,1828478 9,1 4,7 1,936 NA HSI06152 PHD finger 3559 0,0132533 0,2036033 157,6 81,4 1,936 PHF14 protein 14 CDNA FLJ38419 fis, clone FEBRA200984 232 0,0002076 0,0487168 20,9 10,8 1,935 NA 6

zinc finger, MYND domain 2154 0,0055758 0,1413783 41,8 21,6 1,935 ZMYND11 containing 11 phosphoenolpy ruvate carboxykinase 2 3964 0,0160309 0,2211124 404,2 208,9 1,935 PCK2 (mitochondrial) family with sequence similarity 3, 47 2,69E-05 0,0312927 244,6 126,5 1,934 FAM3C member C ATPase, H+ transporting, lysosomal 42kDa, V1 1123 0,0019428 0,0944329 29,2 15,1 1,934 ATP6V1C1 subunit C1 hypothetical protein 5464 0,0283586 0,2837677 85,3 44,1 1,934 LOC153346 LOC153346 Rho-related BTB domain 5492 0,0286274 0,2849969 65,9 34,1 1,933 RHOBTB3 containing 3 solute carrier family 4, sodium bicarbonate cotransporter, 6455 0,0378685 0,3206717 129,7 67,1 1,933 SLC4A7 member 7

hypothetical protein LOC729852 /// hypothetical LOC729852 protein /// LOC730358 /// LOC730358 hypothetical /// protein 254 0,0002396 0,0513945 54,1 28 1,932 LOC730538 LOC730538 methylenetetra hydrofolate dehydrogenas e (NADP+ dependent) 1, methenyltetrah ydrofolate cyclohydrolase , formyltetrahydr ofolate 3481 0,0127627 0,2004556 721,9 373,7 1,932 MTHFD1 synthetase

transmembran e 7 superfamily 243 0,0002259 0,0508275 362,9 187,9 1,931 TM7SF3 member 3 leucyl-tRNA synthetase 2, 1851 0,004268 0,1259529 152 78,7 1,931 LARS2 mitochondrial zinc finger protein 3 homolog 2391 0,006727 0,153734 47,5 24,6 1,931 ZFP3 (mouse) Hypothetical protein 3314 0,0119038 0,1963683 30,9 16 1,931 FLJ32312 FLJ32312

G elongation factor, 6518 0,0384552 0,3224735 181,4 94 1,93 GFM1 mitochondrial 1 chromosome 11 open reading frame 837 0,0012086 0,0789489 1271,5 659,2 1,929 C11orf75 75

transmembran 971 0,0014926 0,0839343 1173,2 608,4 1,928 TMEM30A e protein 30A zinc finger 2232 0,0059031 0,1446021 26,8 13,9 1,928 ZNF680 protein 680 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing 1532 0,0031613 0,1128225 94,4 49 1,927 RCBTB1 protein 1 zinc finger CCCH-type 2593 0,007879 0,1661336 45,1 23,4 1,927 ZC3H14 containing 14 FLJ16542 1469 0,002944 0,1094764 18,1 9,4 1,926 FLJ16542 protein Protein kinase, cAMP- dependent, 3634 0,0136531 0,2052986 13,1 6,8 1,926 PRKACB catalytic, beta CDNA FLJ11925 fis, clone HEMBB10003 4222 0,0180366 0,2334296 70,1 36,4 1,926 NA 54 transmembran 573 0,0006786 0,0646479 15,4 8 1,925 TMEM5 e protein 5 CTD (carboxy- terminal domain, RNA polymerase II, polypeptide A) small phosphatase- 3160 0,0110077 0,1904267 48,3 25,1 1,924 CTDSPL like programmed 302 0,0002971 0,0537879 47,5 24,7 1,923 PDCD2 cell death 2

nuclear cap binding protein subunit 1, 2523 0,0074301 0,1610149 142,7 74,2 1,923 NCBP1 80kDa endothelial PAS domain 3948 0,0159539 0,2208555 1576,4 820,4 1,922 EPAS1 protein 1 protein phosphatase 2 (formerly 2A), regulatory subunit B@#$%&@#$ 4841 0,0229357 0,25895 66,3 34,5 1,922 PPP2R3A %&, alpha dpy-19-like 1 967 0,0014905 0,0839343 102,9 53,6 1,92 DPY19L1 (C. elegans)

glycerol-3- phosphate dehydrogenas e 2 2439 0,0069546 0,1557913 286,2 149,1 1,92 GPD2 (mitochondrial) cofilin 2 2541 0,0075603 0,1626759 14,4 7,5 1,92 CFL2 (muscle) Transcribed 5451 0,0282109 0,2829629 35,9 18,7 1,92 NA locus Zinc finger 3191 0,0112516 0,1927863 54,3 28,3 1,919 ZNF641 protein 641

rabaptin, RAB GTPase binding effector 3371 0,012232 0,1983671 311,6 162,4 1,919 RABEP1 protein 1 mitogen- activated protein kinase associated 1234 0,0022157 0,0980838 187,6 97,8 1,918 MAPKAP1 protein 1

MRNA; cDNA DKFZp434B14 17 (from clone DKFZp434B14 5370 0,0274995 0,2799775 37,4 19,5 1,918 NA 17)

angiogenic factor with G patch and FHA 441 0,0004732 0,0586671 146,1 76,2 1,917 AGGF1 domains 1 SMAD family 925 0,0013885 0,082042 99,1 51,7 1,917 SMAD1 member 1

5605 0,0296149 0,288884 188,1 98,1 1,917 PARVG parvin, gamma serine 710 0,0009219 0,0708321 38,7 20,2 1,916 SRR racemase prolyl endopeptidase- 784 0,0010837 0,0755211 106,9 55,8 1,916 PREPL like 1967 0,0047158 0,131081 141,5 73,9 1,915 KIAA0859 KIAA0859 Transcribed 4974 0,0240535 0,2643999 361,5 188,8 1,915 NA locus

G protein- coupled receptor kinase 338 0,0003434 0,0552439 664,4 347,1 1,914 GIT2 interactor 2 serologically defined colon cancer antigen 3803 0,0148255 0,2130946 78,1 40,8 1,914 SDCCAG8 8 AF4/FMR2 family, member 5151 0,0256416 0,2721713 11,1 5,8 1,914 AFF3 3

tumor necrosis factor (ligand) superfamily, member 13 /// tumor necrosis factor (ligand) TNFSF13 /// superfamily, TNFSF12- member 12- 4024 0,0166009 0,2255021 510,5 266,8 1,913 TNFSF13 member 13 hect domain 4581 0,0208553 0,2489115 28,7 15 1,913 HERC4 and RLD 4 hypothetical 3449 0,012622 0,1999997 10,9 5,7 1,912 CG012 gene CG012 OTU domain 3595 0,0134659 0,2043749 76,1 39,8 1,912 OTUD6B containing 6B hydroxyacyl- Coenzyme A dehydrogenas e/3-ketoacyl- Coenzyme A thiolase/enoyl- Coenzyme A hydratase (trifunctional protein), alpha 6126 0,0347251 0,309864 1719,3 899,3 1,912 HADHA subunit enoyl Coenzyme A hydratase domain 1854 0,0042733 0,1259529 847,5 443,4 1,911 ECHDC1 containing 1 1901 0,0044886 0,1289211 1188,2 621,7 1,911 NA NA Hypothetical protein 5212 0,0261792 0,2746254 43 22,5 1,911 LOC728871 LOC728871

RCSD domain 4164 0,0175772 0,2307957 272,4 142,7 1,909 RCSD1 containing 1 352 0,0003596 0,0556372 84,9 44,5 1,908 GLS glutaminase

3@#$%&(2@# $%&), 5@#$%&- bisphosphate 731 0,0009606 0,0718479 72,7 38,1 1,908 BPNT1 nucleotidase 1 WD repeat 2046 0,0051006 0,1363027 507,3 265,9 1,908 WDR68 domain 68 RAS guanyl releasing protein 3 (calcium and DAG- 3685 0,0139604 0,2071329 332,1 174,1 1,908 RASGRP3 regulated) vacuolar protein sorting 24 homolog (S. 300 0,0002957 0,0537668 732,8 384,3 1,907 VPS24 cerevisiae) Spermidine/sp ermine N1- acetyl transferase-like 396 0,000419 0,0577884 192,2 100,8 1,907 SATL1 1

major facilitator superfamily domain 1671 0,0035902 0,117463 49 25,7 1,907 MFSD3 containing 3 dihydrofolate reductase /// similar to DHFR /// Dihydrofolate 1848 0,0042515 0,1257495 30,3 15,9 1,906 LOC643509 reductase osteopetrosis associated transmembran 297 0,0002891 0,0532207 312,2 163,9 1,905 OSTM1 e protein 1

protein kinase, DNA-activated, catalytic 942 0,0014237 0,0826335 130,7 68,6 1,905 PRKDC polypeptide biliverdin reductase B (flavin reductase 1890 0,0044575 0,128789 2106,9 1106 1,905 BLVRB (NADPH)) carbonyl 5768 0,0310452 0,2942489 80,6 42,3 1,905 CBR4 reductase 4

MRNA; cDNA DKFZp762M12 7 (from clone DKFZp762M12 240 0,0002224 0,0506655 380,9 200,1 1,904 NA 7)

branched chain keto acid dehydrogenas e E1, beta polypeptide (maple syrup 2079 0,005256 0,138226 27,8 14,6 1,904 BCKDHB urine disease)

phosphatidylin ositol 4-kinase, catalytic, alpha 177 0,0001567 0,0481428 413,3 217,2 1,903 PIK4CA polypeptide cystinosis, 574 0,0006787 0,0646479 397,1 208,7 1,903 CTNS nephropathic presenilin 2 (Alzheimer 628 0,0007637 0,0664245 27,6 14,5 1,903 PSEN2 disease 4) Selenophosph ate synthetase 645 0,0008024 0,0680174 47,2 24,8 1,903 SEPHS1 1

hepatoma- derived growth factor, related 3447 0,012619 0,1999997 27,4 14,4 1,903 HDGFRP3 protein 3 engulfment and cell motility 515 0,0005952 0,0631894 71,9 37,8 1,902 ELMO2 2 RWD domain 575 0,0006813 0,0647827 120,8 63,5 1,902 RWDD4A containing 4A Mannosidase, alpha, class 603 0,0007257 0,0657513 789,7 415,3 1,902 MAN2A1 2A, member 1 chromosome 14 open reading frame 3194 0,0112747 0,1929325 115,8 60,9 1,901 C14orf1 1 isocitrate dehydrogenas e 3 (NAD+) 553 0,0006477 0,0640211 119,7 63 1,9 IDH3A alpha potassium channel, subfamily K, 6637 0,039713 0,3271521 267,4 140,8 1,899 KCNK6 member 6 Transcribed 1026 0,0016536 0,0879972 52,2 27,5 1,898 NA locus

guanylate cyclase 1, 1465 0,0029334 0,1093314 14,8 7,8 1,897 GUCY1B3 soluble, beta 3 CDNA FLJ41216 fis, clone BRALZ201762 2082 0,0052694 0,1383062 49,9 26,3 1,897 NA 0

peroxisome proliferator- activated 600 0,0007247 0,0657513 105,4 55,6 1,896 PPARA receptor alpha malic enzyme 2, NAD(+)- dependent, 1401 0,0027195 0,1059917 252,5 133,2 1,896 ME2 mitochondrial palladin, cytoskeletal associated 459 0,0005021 0,059809 3191,1 1684,1 1,895 PALLD protein Suppressor of zeste 12 homolog 1971 0,0047382 0,1314364 14,4 7,6 1,895 SUZ12P pseudogene Impact homolog 3523 0,0130385 0,2023084 113,9 60,1 1,895 IMPACT (mouse) nudix (nucleoside diphosphate linked moiety X)-type motif 3790 0,0147026 0,2121015 12,5 6,6 1,894 NUDT12 12 zinc finger 111 7,82E-05 0,0382725 148,5 78,5 1,892 ZNF650 protein 650 glutamic- oxaloacetic transaminase 1, soluble (aspartate aminotransfera 194 0,000171 0,0481929 204,2 107,9 1,892 GOT1 se 1) 361 0,0003724 0,0564016 24,6 13 1,892 GPHN gephyrin

A kinase (PRKA) anchor 518 0,0006019 0,0635307 67,5 35,7 1,891 AKAP7 protein 7 Protein kinase 6018 0,0335223 0,3045583 95,3 50,4 1,891 PRKCB1 C, beta 1 alkylglycerone phosphate 325 0,0003269 0,0549946 226,2 119,7 1,89 AGPS synthase 803 0,0011163 0,0760071 35,7 18,9 1,889 KIAA1919 KIAA1919 fatty acid 2638 0,0080898 0,167497 728,8 385,9 1,889 FADS1 desaturase 1 dpy-19-like 1 2702 0,0083777 0,1695229 30,6 16,2 1,889 DPY19L1 (C. elegans) hypothetical protein 720 0,0009335 0,0708877 37 19,6 1,888 LOC158402 LOC158402 solute carrier family 35, 965 0,0014888 0,0839343 212,8 112,7 1,888 SLC35B3 member B3 NHL repeat 1642 0,0034892 0,1161645 16,8 8,9 1,888 NHLRC2 containing 2 low density lipoprotein receptor adaptor protein 3221 0,0113878 0,193258 92,3 48,9 1,888 LDLRAP1 1

ring finger and SPRY domain 3669 0,0138839 0,2068577 97,8 51,8 1,888 RSPRY1 containing 1 ubiquitin carboxyl- terminal esterase L3 (ubiquitin 4048 0,0167706 0,226515 491,4 260,3 1,888 UCHL3 thiolesterase) zinc finger, FYVE domain 93 6,27E-05 0,0367348 224,6 119 1,887 ZFYVE26 containing 26

polymerase (RNA) III (DNA directed) polypeptide K, 3188 0,011201 0,1921 216,2 114,6 1,887 POLR3K 12.3 kDa ATP-binding cassette, sub- family C (CFTR/MRP), 7334 0,0474426 0,3536848 1067,7 565,7 1,887 ABCC3 member 3

Chromosome 8 open reading 226 0,0002015 0,0487017 14,9 7,9 1,886 C8orf70 frame 70

coiled-coil domain 823 0,0011662 0,0773734 284,8 151 1,886 CCDC132 containing 132 CDNA: FLJ23228 fis, clone 1371 0,0026363 0,1048471 66,4 35,2 1,886 NA CAE06654 outer dense fiber of sperm 1449 0,0028626 0,1080143 37,7 20 1,885 ODF2 tails 2 mitochondrial ribosomal 2816 0,0090182 0,1750784 2178,7 1155,9 1,885 MRPS6 protein S6 MRS2-like, magnesium homeostasis factor (S. 3665 0,013838 0,2064373 49,4 26,2 1,885 MRS2L cerevisiae) RP11- KIAA0564 4775 0,0224399 0,2569427 91,6 48,6 1,885 125A7.3 protein hypothetical protein 5616 0,0296841 0,2889396 24,5 13 1,885 LOC646916 LOC646916 Zinc finger 1778 0,0039855 0,1224818 24,3 12,9 1,884 ZNF609 protein 609 nicotinamide nucleotide transhydrogen 244 0,0002287 0,0510448 163,8 87 1,883 NNT ase

RAB, member of RAS oncogene family-like 3 /// similar to RAB, member of RABL3 /// RAS oncogene 765 0,0010498 0,0750247 71,7 38,1 1,882 LOC653256 family-like 3

dihydrouridine synthase 4-like 1137 0,0019704 0,0946254 55,9 29,7 1,882 DUS4L (S. cerevisiae)

solute carrier family 8 (sodium/calciu m exchanger), 6872 0,0423436 0,3368398 49,3 26,2 1,882 SLC8A1 member 1

ribosomal protein S6 kinase, 90kDa, 238 0,0002196 0,050448 566,8 301,3 1,881 RPS6KA1 polypeptide 1 CDNA clone IMAGE:482560 2478 0,0071963 0,1587803 11,1 5,9 1,881 NA 6 pentatricopepti de repeat 6218 0,0356498 0,3134694 50,8 27 1,881 PTCD2 domain 2 adducin 3 387 0,000411 0,0577756 568,1 302,2 1,88 ADD3 (gamma) ras homolog gene family, 2245 0,0060088 0,1463323 138,4 73,6 1,88 RHOQ member Q

vacuolar protein sorting 24 homolog (S. 293 0,0002868 0,0532207 495,6 263,8 1,879 VPS24 cerevisiae)

aspartate beta- hydroxylase domain 438 0,0004686 0,0584948 40,2 21,4 1,879 ASPHD1 containing 1 Transcribed 482 0,0005444 0,0615795 159 84,6 1,879 NA locus

ubiquitin-like domain containing CTD 790 0,0010949 0,0757259 229,1 121,9 1,879 UBLCP1 phosphatase 1 1726 0,003776 0,1195727 17,1 9,1 1,879 NA NA family with sequence similarity 69, 1902 0,0044889 0,1289211 311,6 165,8 1,879 FAM69A member A FLJ20160 3129 0,0107789 0,1883466 77,4 41,2 1,879 FLJ20160 protein

oxidoreductase NAD-binding domain 175 0,0001553 0,0481428 107,4 57,2 1,878 OXNAD1 containing 1 sorting and assembly machinery component 50 homolog (S. 1012 0,0016034 0,0866252 530,3 282,4 1,878 SAMM50 cerevisiae)

Full-length cDNA clone CS0DL007YI2 4 of B cells (Ramos cell line) Cot 25- normalized of Homo sapiens 1055 0,0017184 0,0890555 190,1 101,2 1,878 NA (human) brain protein 1324 0,0025065 0,1035067 955,7 508,8 1,878 BRP44L 44-like 3319 0,0119338 0,1965014 53,9 28,7 1,878 FXN frataxin IQ motif 891 0,0013029 0,0799223 33,6 17,9 1,877 IQCK containing K Isocitrate dehydrogenas e 1 (NADP+), 1334 0,0025272 0,1035792 34,9 18,6 1,876 IDH1 soluble

ST6 (alpha-N- acetyl- neuraminyl-2,3- beta-galactosyl- 1,3)-N- acetylgalactos aminide alpha- 2,6- ST6GALNA sialyltransferas 1355 0,0025772 0,1039631 112,4 59,9 1,876 C4 e 4 transforming growth factor, 2175 0,0056529 0,1421022 39,2 20,9 1,876 TGFA alpha unc-51-like kinase 2 (C. 2204 0,0058065 0,1439874 21,2 11,3 1,876 ULK2 elegans) chloride channel 5 (nephrolithiasis 2, X-linked, 4529 0,0204726 0,2471223 261,5 139,4 1,876 CLCN5 Dent disease) 5603 0,0296034 0,2888341 37,9 20,2 1,876 VASH1 vasohibin 1

transmembran e and coiled- 956 0,0014676 0,0839341 109,7 58,5 1,875 TMCO3 coil domains 3 chromosome 19 open reading frame 1192 0,0021163 0,0969771 538,4 287,1 1,875 C19orf28 28

transmembran e and coiled- 79 5,16E-05 0,0357118 538,9 287,6 1,874 TMCO3 coil domains 3 peroxisomal biogenesis 7105 0,0449065 0,3455683 52,1 27,8 1,874 PEX12 factor 12 KIAA0143 78 5,15E-05 0,0357118 584,2 311,9 1,873 KIAA0143 protein

phosphatidylin ositol binding clathrin assembly 89 6,13E-05 0,0367348 1046,7 558,9 1,873 PICALM protein

MRNA; cDNA DKFZp762M12 7 (from clone DKFZp762M12 198 0,0001792 0,0483249 309,3 165,1 1,873 NA 7) absent in 333 0,0003386 0,0552439 798,8 426,4 1,873 AIM1 melanoma 1 prenyl (decaprenyl) diphosphate synthase, 1859 0,0042892 0,1261495 153 81,7 1,873 PDSS2 subunit 2 phosphoinositi de-3-kinase, regulatory subunit 1 (p85 2749 0,0086764 0,1725654 268,9 143,6 1,873 PIK3R1 alpha) 2807 0,0089885 0,1750515 25,1 13,4 1,873 SUOX sulfite oxidase phosphodieste 4566 0,0207242 0,2481594 101,5 54,2 1,873 PDE8A rase 8A

Full-length cDNA clone CS0DE011YO 20 of Placenta of Homo sapiens 309 0,0003074 0,0541231 249 133 1,872 NA (human) cystinosis, 1132 0,0019575 0,0945462 606,3 323,9 1,872 CTNS nephropathic

Mdm4, transformed 3T3 cell double minute 1, p53 binding protein 4025 0,0166052 0,2255021 36,5 19,5 1,872 MDM1 (mouse) OMA1 homolog, zinc metallopeptida se (S. 5914 0,0324598 0,3000912 89,1 47,6 1,872 OMA1 cerevisiae) mitochondrial carrier homolog 2 (C. 581 0,0007008 0,0657513 254,8 136,2 1,871 MTCH2 elegans) GLI pathogenesis- related 1 1383 0,0026521 0,1048471 1159,7 619,9 1,871 GLIPR1 (glioma) 2810 0,0089974 0,1750631 157,7 84,3 1,871 KIAA1370 KIAA1370

protein kinase, DNA-activated, catalytic 3021 0,0101243 0,1832282 180,4 96,4 1,871 PRKDC polypeptide 5499 0,0287069 0,2853975 221,3 118,3 1,871 KIAA1430 KIAA1430

A kinase (PRKA) anchor 937 0,0014178 0,082425 72,2 38,6 1,87 AKAP1 protein 1 pyridoxamine 5@#$%&- phosphate 2956 0,009751 0,1803277 170,8 91,4 1,869 PNPO oxidase interferon gamma 1399 0,0027092 0,1058796 3895,6 2087,6 1,866 IFNGR1 receptor 1 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta 2077 0,0052414 0,1379747 79,1 42,4 1,866 PPP2R1B isoform 4436 0,0197334 0,2432199 25 13,4 1,866 NA NA ATM/ATR- Substrate Chk2- Interacting Zn2+-finger 189 0,000167 0,0481428 199,7 107,1 1,865 ASCIZ protein

glycerol-3- phosphate dehydrogenas e 2 673 0,0008602 0,069812 61 32,7 1,865 GPD2 (mitochondrial) chromosome 22 open reading frame 1497 0,0030175 0,1102083 812,6 435,7 1,865 C22orf9 9 TruB pseudouridine (psi) synthase homolog 1 (E. 1672 0,0035921 0,117463 87 46,7 1,863 TRUB1 coli)

Growth arrest- GAS2L3 /// specific 2 like 3 3567 0,0132941 0,2037257 582,5 312,8 1,862 MTPN /// Myotrophin

single stranded DNA binding protein 3 /// interleukin 17 receptor B /// similar to single- stranded DNA- binding protein isoform a; Lck- associated signal SSBP3 /// transducer /// IL17RB /// similar to LOC401002 single stranded /// DNA binding 5203 0,0261372 0,2745585 160,3 86,1 1,862 LOC646674 protein 3 abhydrolase domain 5585 0,0294358 0,2880914 241,9 129,9 1,862 ABHD2 containing 2 CDNA FLJ33255 fis, clone ASTRO200555 775 0,0010667 0,075254 34,8 18,7 1,861 NA 3 mitochondrial carrier homolog 2 (C. 1396 0,0026912 0,1053462 1061,1 570,3 1,861 MTCH2 elegans) Transcribed 5702 0,0304883 0,2923444 18,8 10,1 1,861 NA locus zinc finger 306 0,0003019 0,0539424 24 12,9 1,86 ZNF268 protein 268 Fanconi anemia, complementati 2382 0,0066768 0,1532553 39,8 21,4 1,86 FANCF on group F fatty acid 4223 0,018037 0,2334296 680,7 365,9 1,86 FADS1 desaturase 1 pyruvate dehydrogenas e (lipoamide) 251 0,0002348 0,0511462 514,4 276,7 1,859 PDHB beta RAN binding 1091 0,0018148 0,0908997 92,2 49,6 1,859 RANBP2 protein 2

protein kinase, AMP-activated, alpha 1 catalytic 2418 0,0068789 0,1555358 52,6 28,3 1,859 PRKAA1 subunit potassium channel tetramerisation domain 2470 0,0071193 0,1575884 485,3 261,1 1,859 KCTD6 containing 6 chromosome 10 open reading frame 3514 0,0130034 0,2023084 583,4 313,8 1,859 C10orf22 22 zinc finger 4270 0,0183536 0,2349656 31,6 17 1,859 ZNF260 protein 260 MyoD family inhibitor domain 2775 0,008799 0,1732398 84 45,2 1,858 MDFIC containing transmembran e and coiled- coil domain 868 0,0012619 0,0791194 16,9 9,1 1,857 TMCC1 family 1

IKAROS family zinc finger 1 3121 0,0107246 0,1878781 9,1 4,9 1,857 IKZF1 (Ikaros) microsomal glutathione S- 262 0,0002511 0,0521767 269 144,9 1,856 MGST2 transferase 2 TDP-glucose 4,6- 619 0,0007444 0,0657513 118,4 63,8 1,856 TGDS dehydratase

acireductone 2033 0,0050449 0,1356763 1104,1 594,9 1,856 ADI1 dioxygenase 1 Transcriptional regulating 3901 0,0155947 0,2185697 156,1 84,1 1,856 TRERF1 factor 1 transmembran 4295 0,0185914 0,236667 385,8 207,9 1,856 TMEM33 e protein 33 60 3,94E-05 0,0353731 213,4 115,1 1,854 KIAA1815 KIAA1815 basic, immunoglobuli n-like variable motif 5196 0,0260163 0,2737253 19,1 10,3 1,854 BIVM containing solute carrier family 33 (acetyl-CoA transporter), 1964 0,0046997 0,130833 149,7 80,8 1,853 SLC33A1 member 1 SFRS protein 2213 0,0058396 0,1441488 125,6 67,8 1,853 SRPK2 kinase 2 HEAT repeat 2656 0,0081674 0,1681297 31,5 17 1,853 HEATR2 containing 2

eukaryotic translation initiation factor 2B, subunit 3 172 0,0001539 0,0481428 194,1 104,8 1,852 EIF2B3 gamma, 58kDa 246 0,00023 0,0510448 170,9 92,3 1,852 SETX senataxin methyltransfer 1832 0,0041673 0,1243707 1828,6 987,2 1,852 METTL7A ase like 7A

chromosome 6 open reading 2588 0,0078421 0,1656209 523,3 282,5 1,852 C6orf108 frame 108 DKFZP586P hypothetical 413 0,0004412 0,0577884 97,9 52,9 1,851 0123 protein

chromosome X open reading 894 0,00131 0,0800515 1097,6 593 1,851 CXorf9 frame 9 Homeodomain interacting protein kinase 186 0,0001654 0,0481428 1385 748,7 1,85 HIPK2 2 ATP-binding cassette, sub- family E (OABP), 2093 0,0053122 0,1387424 314,3 169,9 1,85 ABCE1 member 1

p53-associated parkin-like cytoplasmic 2192 0,0057332 0,1430031 79,9 43,2 1,85 PARC protein Hypothetical 5149 0,0256384 0,2721713 22,2 12 1,85 LOC646324 LOC646324 Transcribed 4635 0,0212921 0,2511641 82,3 44,5 1,849 NA locus short coiled- 185 0,0001654 0,0481428 475,4 257,4 1,847 SCOC coil protein choline/ethanol amine phosphotransf 1718 0,003749 0,1193112 311,1 168,4 1,847 CEPT1 erase 1 PTK2 protein tyrosine kinase 2051 0,0051319 0,1367834 77 41,7 1,847 PTK2 2 CD40 molecule, TNF receptor superfamily 4126 0,0172989 0,2292071 31,4 17 1,847 CD40 member 5 translocation 552 0,0006458 0,0639658 116,3 63 1,846 TLOC1 protein 1 Transcribed 2719 0,0084966 0,1708071 75,5 40,9 1,846 NA locus Isocitrate dehydrogenas e 1 (NADP+), 4508 0,0202955 0,2460654 39,5 21,4 1,846 IDH1 soluble

FK506 binding protein 12- rapamycin associated 393 0,0004165 0,0577756 38 20,6 1,845 FRAP1 protein 1 tripartite motif- containing 34 /// tripartite motif- containing 6 TRIM34 /// and tripartite TRIM6- motif- 2101 0,0053485 0,1391857 174,2 94,4 1,845 TRIM34 containing 34

transmembran e 6 superfamily 2322 0,0063771 0,1498086 610,7 331 1,845 TM6SF1 member 1 Heat shock protein 90kDa beta (Grp94), 2754 0,0086995 0,1727107 81 43,9 1,845 HSP90B1 member 1 zinc finger DAZ interacting 2449 0,0070418 0,1571828 68,6 37,2 1,844 DZIP3 protein 3 GA binding protein transcription factor, beta 2978 0,0098831 0,1813981 33 17,9 1,844 GABPB2 subunit 2 reversion- inducing- cysteine-rich protein with 5092 0,0251055 0,269445 14,2 7,7 1,844 RECK kazal motifs chromosome 14 open reading frame 1112 0,0018915 0,0929475 79,6 43,2 1,843 C14orf126 126 hypothetical protein 120 8,86E-05 0,0403684 35,9 19,5 1,841 FLJ13611 FLJ13611 Rho guanine nucleotide exchange 707 0,0009114 0,070482 331,2 179,9 1,841 ARHGEF3 factor (GEF) 3 reticulocalbin 2, EF-hand calcium 1567 0,003267 0,1138946 171,4 93,1 1,841 RCN2 binding domain ubiquitination factor E4B (UFD2 homolog, 2315 0,0063469 0,1498086 56,9 30,9 1,841 UBE4B yeast) Transcribed 2932 0,0096296 0,1795697 387,5 210,6 1,84 NA locus

fatty acid binding protein 3445 0,0126109 0,1999997 11165 6066,6 1,84 FABP4 4, adipocyte family with sequence similarity 20, 3760 0,0144238 0,2097397 67,9 36,9 1,84 FAM20A member A nuclear receptor co- 107 7,55E-05 0,0382725 237 128,9 1,839 NCOR1 repressor 1 haloacid dehalogenase- like hydrolase domain containing 3 /// haloacid dehalogenase- like hydrolase domain 222 0,000197 0,0483249 51,5 28 1,839 HDHD3 containing 3 FAST kinase 2626 0,0080623 0,167497 363,4 197,6 1,839 FASTKD1 domains 1 THUMP domain 2689 0,0083467 0,1695229 45,6 24,8 1,839 THUMPD3 containing 3

glutathione S- 4308 0,0186715 0,2369335 39,9 21,7 1,839 GSTM4 transferase M4 chromosome 12 open reading frame 7177 0,0456813 0,3479021 16 8,7 1,839 C12orf59 59 F-box protein 38 /// F-box 2922 0,0095118 0,17798 257,1 139,9 1,838 FBXO38 protein 38

Eukaryotic translation initiation factor 4E binding 3011 0,0100726 0,1828781 60,8 33,1 1,837 EIF4EBP2 protein 2 cytosolic ovarian carcinoma 3198 0,0112866 0,1929329 48,5 26,4 1,837 COVA1 antigen 1 stromal 1119 0,0019181 0,0937195 59,3 32,3 1,836 STAG3 antigen 3 Programmed 4765 0,0223173 0,2560628 21,3 11,6 1,836 PDCD6 cell death 6 zinc finger 5215 0,0262159 0,2748522 11,2 6,1 1,836 ZNF585A protein 585A 7547 0,0496718 0,3598523 53,8 29,3 1,836 NA NA 1788 0,0040205 0,1229423 1319,7 719,2 1,835 ANXA4 annexin A4 ubiquitination factor E4B (UFD2 homolog, 2606 0,0079471 0,1666005 52,3 28,5 1,835 UBE4B yeast) Anaphase promoting complex 414 0,0004417 0,0577884 53 28,9 1,834 ANAPC1 subunit 1 RP11- 535 0,0006295 0,0635709 38,7 21,1 1,834 298P3.3 CG016

amyloid beta (A4) precursor protein- binding, family B, member 1 interacting 1109 0,0018782 0,0925975 86,2 47 1,834 APBB1IP protein ubiquitin specific peptidase 13 (isopeptidase T- 3653 0,0137332 0,2055469 27,7 15,1 1,834 USP13 3) O- sialoglycoprote in endopeptidase- 3919 0,0157113 0,2191822 95,7 52,2 1,833 OSGEPL1 like 1 RNA binding motif protein 5328 0,0271445 0,2785521 77 42 1,833 RBM41 41 acyl- Coenzyme A oxidase 1, 6683 0,0403758 0,3302902 101,9 55,6 1,833 ACOX1 palmitoyl

3473 0,0127231 0,2002405 145,8 79,6 1,832 ALPK1 alpha-kinase 1 6289 0,0363883 0,3162557 98,4 53,7 1,832 NINJ2 ninjurin 2 carnitine palmitoyltransf 229 0,0002056 0,0487168 171,6 93,7 1,831 CPT2 erase II zinc finger 1867 0,0043325 0,126877 82,2 44,9 1,831 ZNF576 protein 576 glucosamine (N-acetyl)-6- sulfatase (Sanfilippo 517 0,0005978 0,06322 252,5 138 1,83 GNS disease IIID) tumor necrosis factor (ligand) superfamily, member 13 /// tumor necrosis factor (ligand) TNFSF13 /// superfamily, TNFSF12- member 12- 2514 0,0073797 0,1604953 706,1 385,8 1,83 TNFSF13 member 13 Transcribed 747 0,0009969 0,0729195 141,4 77,3 1,829 NA locus adenylate cyclase 1 1217 0,0021836 0,097918 15 8,2 1,829 ADCY1 (brain) Transcribed 3298 0,0117833 0,1953285 35,3 19,3 1,829 NA locus 426 0,0004532 0,0577884 1381,9 755,8 1,828 CCNH cyclin H Sec61 alpha 1 subunit (S. 3459 0,0126539 0,200015 183,2 100,2 1,828 SEC61A1 cerevisiae) hypothetical protein 5063 0,0248484 0,2682755 218,3 119,4 1,828 FLJ90757 LOC440465 hypothetical protein 694 0,0008983 0,070427 922,4 504,9 1,827 LOC150166 LOC150166 selenoprotein 738 0,0009722 0,0720258 939,3 514,2 1,827 SEPX1 X, 1 zinc finger, DHHC-type 7104 0,0448677 0,3453183 154,6 84,6 1,827 ZDHHC2 containing 2 valyl-tRNA 626 0,0007631 0,0664245 141 77,2 1,826 VARS synthetase carbonyl 743 0,0009874 0,0726596 95,7 52,4 1,826 CBR4 reductase 4 DnaJ (Hsp40) homolog, subfamily C, 1097 0,0018383 0,0916217 202 110,6 1,826 DNAJC16 member 16 hypothetical protein 2214 0,0058397 0,1441488 82,9 45,4 1,826 MGC3260 MGC3260 Methylcrotonoy l-Coenzyme A carboxylase 2 7178 0,0456815 0,3479021 23 12,6 1,825 MCCC2 (beta) spermatid perinuclear RNA binding 2045 0,0050996 0,1363027 81,9 44,9 1,824 STRBP protein Homeodomain interacting protein kinase 2695 0,0083641 0,1695229 991,6 543,7 1,824 HIPK2 2 1414 0,0027559 0,1065236 17,5 9,6 1,823 NA NA

basic leucine zipper transcription 590 0,0007124 0,0657513 160,5 88,1 1,822 BATF factor, ATF-like F-box protein 793 0,0011008 0,0757259 24,6 13,5 1,822 FBXO38 38 arginyl aminopeptidas e (aminopeptida 2227 0,0058719 0,1441608 794,5 436,1 1,822 RNPEP se B) 2475 0,0071851 0,1587254 218,6 120 1,822 STX7 Syntaxin 7 3218 0,0113837 0,193258 28,6 15,7 1,822 NA NA

3377 0,0122591 0,1984192 633,9 347,9 1,822 CD84 CD84 molecule palladin, cytoskeletal associated 316 0,000313 0,0541231 2449,4 1345,3 1,821 PALLD protein

family with sequence 1950 0,004642 0,1301355 15,3 8,4 1,821 FAM122A similarity 122A adhesion molecule with Ig-like domain 2146 0,0055421 0,1411996 20,4 11,2 1,821 AMIGO2 2 zinc finger, DHHC-type 2240 0,005977 0,1458895 35,5 19,5 1,821 ZDHHC13 containing 13 ClpX caseinolytic peptidase X homolog (E. 2347 0,0064876 0,1510758 87,4 48 1,821 CLPX coli) choroideremia (Rab escort 294 0,0002872 0,0532207 200,6 110,2 1,82 CHM protein 1) insulin-like growth factor 2 3062 0,0104216 0,1860378 542,7 298,2 1,82 IGF2R receptor

FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte- 4993 0,0242302 0,2652969 74,8 41,1 1,82 FARP1 derived) potassium channel tetramerisation domain 5397 0,0277668 0,2812951 62,8 34,5 1,82 KCTD6 containing 6 ankyrin repeat and FYVE domain 1363 0,0025976 0,1040748 350,3 192,6 1,819 ANKFY1 containing 1

Chromosome 8 open reading 2805 0,0089817 0,1750515 17,1 9,4 1,819 C8orf38 frame 38 cofilin 2 (muscle) /// cofilin 2 5465 0,028364 0,2837698 70,2 38,6 1,819 CFL2 (muscle) chromosome 1 open reading 1335 0,0025365 0,1036037 16 8,8 1,818 C1orf96 frame 96

similar to Heparan- sulfate 6-O- sulfotransferas 835 0,0012049 0,0788957 117,4 64,6 1,817 LOC728969 e 1 (HS6ST-1)

transmembran 1957 0,0046648 0,130326 45,8 25,2 1,817 TMEM86A e protein 86A mindbomb homolog 1 2049 0,0051268 0,1367834 60,7 33,4 1,817 MIB1 (Drosophila) 4413 0,0195681 0,2424292 135,3 74,5 1,816 KIAA1737 KIAA1737 tumor protein p53 (Li- Fraumeni 7189 0,0458559 0,3487276 69,7 38,4 1,815 TP53 syndrome) chromosome 10 open reading frame 114 8,07E-05 0,0382725 44,8 24,7 1,814 C10orf97 97 UBX domain 1035 0,001667 0,0879972 89,8 49,5 1,814 UBXD6 containing 6 scavenger receptor class 3888 0,0154914 0,2178478 104,3 57,5 1,814 SCARB2 B, member 2

splicing factor, arginine/serine- 6149 0,0349471 0,3107388 322,9 178 1,814 SFRS7 rich 7, 35kDa

solute carrier family 8 (sodium/calciu m exchanger), 4621 0,0211994 0,2508282 49,5 27,3 1,813 SLC8A1 member 1

homeobox, hematopoietica 6323 0,036728 0,3175871 159,4 87,9 1,813 HHEX lly expressed transmembran 7411 0,0482393 0,3558862 30,1 16,6 1,813 TMEM68 e protein 68

UDP glycosyltransfe rase 3 family, 191 0,0001699 0,0481929 13,4 7,4 1,811 UGT3A1 polypeptide A1 zinc finger 3202 0,0112997 0,1929329 48 26,5 1,811 ZNF721 protein 721

inhibitor of Bruton agammaglobuli nemia tyrosine 192 0,0001703 0,0481929 481,7 266,2 1,81 IBTK kinase family with sequence 705 0,000909 0,070427 76 42 1,81 FAM121A similarity 121A

UDP-N-acetyl- alpha-D- galactosamine: polypeptide N- acetylgalactos aminyltransfer ase 7 (GalNAc- 1242 0,0022377 0,0985074 485,1 268 1,81 GALNT7 T7) mannose-6- phosphate receptor (cation 3862 0,0153492 0,2173013 1279,6 706,9 1,81 M6PR dependent)

resistance to inhibitors of cholinesterase 8 homolog B 5726 0,0307305 0,2934317 48,7 26,9 1,81 RIC8B (C. elegans)

Family with sequence 1370 0,0026354 0,1048471 228,6 126,4 1,809 FAM121A similarity 121A 704 0,0009088 0,070427 56,6 31,3 1,808 NA NA DENN/MADD domain 886 0,0012896 0,079454 1089,1 602,4 1,808 DENND4C containing 4C arylsulfatase family, member 3843 0,0151889 0,216095 60,4 33,4 1,808 ARSK K Zinc finger 5931 0,0325848 0,3003688 18,8 10,4 1,808 ZNF224 protein 224 CDNA FLJ32438 fis, clone SKMUS20014 2423 0,0068972 0,1555779 75,9 42 1,807 NA 02 Similar to ankyrin repeat 2660 0,0082096 0,1687282 10,3 5,7 1,807 LOC643187 domain 20A chloride 4474 0,0199862 0,2442435 54,2 30 1,807 CLCN3 channel 3 6968 0,0435399 0,3415944 484,2 268 1,807 VCL vinculin MKL/myocardi 443 0,0004766 0,0587756 98,4 54,5 1,806 MKL2 n-like 2 GLI pathogenesis- related 1 1927 0,004564 0,129476 1223,5 677,3 1,806 GLIPR1 (glioma)

chromosome 3 open reading 2609 0,0079499 0,1666005 115,6 64 1,806 C3orf14 frame 14 nemo-like 4157 0,0175301 0,2305649 56,9 31,5 1,806 NLK kinase 4688 0,0217329 0,2534655 485,3 268,7 1,806 SORT1 sortilin 1 4699 0,0218328 0,2539817 13 7,2 1,806 NA NA ATG7 autophagy related 7 homolog (S. 887 0,001291 0,079454 207,7 115,1 1,805 ATG7 cerevisiae)

chromosome 1 open reading 2314 0,0063445 0,1498086 48,2 26,7 1,805 C1orf156 frame 156 inositol hexaphosphat 2684 0,0083227 0,169519 72,2 40 1,805 IHPK2 e kinase 2 phosphoinositi de-3-kinase, class 2, beta 3000 0,0100173 0,1825536 109 60,4 1,805 PIK3C2B polypeptide

chromosome 1 open reading 408 0,000435 0,0577884 567,4 314,6 1,804 C1orf96 frame 96 cleavage and polyadenylatio n specific factor 2, 620 0,0007463 0,0658128 215,6 119,5 1,804 CPSF2 100kDa solute carrier family 37 (glycerol-3- phosphate transporter), 3748 0,0143258 0,2089303 270,1 149,7 1,804 SLC37A2 member 2 4264 0,0183124 0,2347794 90,4 50,1 1,804 GLS glutaminase

adaptor-related protein complex 4, epsilon 1 4346 0,0189886 0,2388867 90,4 50,1 1,804 AP4E1 subunit myeloid cell nuclear differentiation antigen /// myeloid cell nuclear differentiation 5762 0,0310039 0,2941927 1427,1 791,1 1,804 MNDA antigen ATPase, H+ transporting, lysosomal 70kDa, V1 6935 0,0431059 0,3398436 878,7 487,1 1,804 ATP6V1A subunit A

Synaptojanin 2 427 0,0004557 0,0577884 34,8 19,3 1,803 SYNJ2BP binding protein DPH4, JJJ3 homolog (S. 2665 0,0082309 0,1688157 115,6 64,1 1,803 DPH4 cerevisiae) TBC1 domain family, member 2018 0,004957 0,1343033 198,8 110,3 1,802 TBC1D10C 10C hypothetical LOC387723 /// LOC387723 hypothetical /// protein 6407 0,0373473 0,3187082 30,1 16,7 1,802 LOC651940 LOC651940 nucleoporin 4327 0,0188113 0,2376045 54,2 30,1 1,801 NUP210 210kDa

MRNA; cDNA DKFZp667B17 18 (from clone DKFZp667B17 4982 0,0241577 0,2650734 201,2 111,7 1,801 NA 18)

5160 0,0257236 0,2723069 201,5 111,9 1,801 GK glycerol kinase

cAMP responsive element binding protein 153 0,0001268 0,0449393 464,7 258,2 1,8 CREB3L2 3-like 2 768 0,0010589 0,075254 9 5 1,8 FST follistatin TNF receptor- associated factor 3 interacting 604 0,0007321 0,0657513 25,9 14,4 1,799 TRAF3IP1 protein 1

UPF3 regulator of nonsense transcripts homolog A 1678 0,0036197 0,1177064 165,7 92,1 1,799 UPF3A (yeast) phosphatidylin ositol glycan anchor biosynthesis, 2699 0,0083693 0,1695229 93,9 52,2 1,799 PIGK class K

NADH dehydrogenas e (ubiquinone) Fe-S protein 1, 75kDa (NADH- coenzyme Q 2848 0,0091684 0,1759771 93,9 52,2 1,799 NDUFS1 reductase) leucyl/cystinyl aminopeptidas 5091 0,025103 0,269445 220,9 122,8 1,799 LNPEP e

ATP-binding cassette, sub- family D (ALD), 2034 0,0050511 0,1357078 325,3 180,9 1,798 ABCD3 member 3 aldehyde dehydrogenas e 3 family, 962 0,0014822 0,0839343 161,9 90,1 1,797 ALDH3A2 member A2 sialidase 1 (lysosomal 1061 0,0017304 0,0891702 868,4 483,4 1,796 NEU1 sialidase) leucine-rich repeats and immunoglobuli n-like domains 1 /// leucine- rich repeats and immunoglobuli n-like domains 2075 0,0052254 0,1376861 20,3 11,3 1,796 LRIG1 1

ubiquitin protein ligase E3 component 2493 0,0072741 0,1595313 178,5 99,4 1,796 UBR1 n-recognin 1 zinc finger 800 0,0011092 0,0757259 36,8 20,5 1,795 ZNF43 protein 43 gem (nuclear organelle) associated 2208 0,0058248 0,1441488 75,4 42 1,795 GEMIN5 protein 5

UDP-N-acetyl- alpha-D- galactosamine: polypeptide N- acetylgalactos aminyltransfer ase 7 (GalNAc- 4604 0,0210623 0,2501262 162,3 90,4 1,795 GALNT7 T7) nucleolar 5434 0,0281282 0,2828411 211,5 117,8 1,795 NOL8 protein 8 ZW10 904 0,0013328 0,0805159 83,6 46,6 1,794 ZWINT interactor Transcribed 1525 0,003118 0,111788 40,9 22,8 1,794 NA locus hect domain 5927 0,0325643 0,3003688 69,6 38,8 1,794 HERC4 and RLD 4 chromosome 12 open reading frame 6509 0,0383647 0,3222599 922,9 514,3 1,794 C12orf5 5 complement component (3b/4b) receptor 1 (Knops blood group) /// complement component (3b/4b) receptor 1-like /// similar to complement component (3b/4b) CR1 /// receptor 1 CR1L /// isoform F 1954 0,0046523 0,1301763 179,1 99,9 1,793 LOC653907 precursor apoptosis, caspase activation 2013 0,004944 0,1341912 74,4 41,5 1,793 AVEN inhibitor G elongation factor, 2036 0,0050539 0,1357078 227,3 126,8 1,793 GFM1 mitochondrial 1

RNPEP /// UBE2V1 /// Kua /// Kua- UEV /// LOC730052 /// 2428 0,0069136 0,1555897 698,8 389,8 1,793 LOC732137 NA chromosome 21 open reading frame 3192 0,0112613 0,1928625 94,3 52,6 1,793 C21orf6 6

uncoupling protein 2 (mitochondrial, 3722 0,0141858 0,2083539 511,4 285,2 1,793 UCP2 proton carrier) Transcribed 4501 0,0202492 0,2459731 54,7 30,5 1,793 NA locus

tRNA nucleotidyl transferase, 4873 0,0231777 0,2599793 157,6 87,9 1,793 TRNT1 CCA-adding, 1

Similar to FRG1 protein (FSHD region 2059 0,0051584 0,1368599 13,8 7,7 1,792 MGC72104 gene 1 protein) bolA homolog 4065 0,0168605 0,2266761 595,4 332,2 1,792 BOLA3 3 (E. coli) peroxiredoxin 224 0,0001984 0,0484264 861 480,7 1,791 PRDX4 4 hypothetical protein 528 0,0006175 0,0635709 65,9 36,8 1,791 LOC90784 LOC90784 alkylglycerone phosphate 695 0,0008984 0,070427 118,4 66,1 1,791 AGPS synthase

protein kinase, AMP-activated, alpha 1 catalytic 2599 0,0079231 0,1666005 28,3 15,8 1,791 PRKAA1 subunit CASP8 associated 2869 0,009252 0,1762631 57,5 32,1 1,791 CASP8AP2 protein 2

ribonuclease P 4081 0,0169834 0,2275343 60,7 33,9 1,791 RPP25 25kDa subunit stromal interaction 6521 0,0384609 0,3224735 19,7 11 1,791 STIM2 molecule 2 PAX interacting (with transcription- activation domain) 6778 0,0415029 0,3347848 54,8 30,6 1,791 PAXIP1 protein 1 909 0,0013418 0,0807073 297,3 166,1 1,79 STX7 Syntaxin 7 ATP-binding cassette, sub- family C (CFTR/MRP), 3304 0,0118612 0,196206 65,1 36,4 1,788 ABCC5 member 5

7- dehydrocholest 6222 0,0356847 0,3135746 64 35,8 1,788 DHCR7 erol reductase HD domain 744 0,0009942 0,0729195 26,8 15 1,787 HDDC2 containing 2 cytosolic ovarian carcinoma 1117 0,001917 0,0937195 24,3 13,6 1,787 COVA1 antigen 1 protein phosphatase 1, regulatory 2206 0,0058105 0,1440114 677,7 379,2 1,787 PPP1R7 subunit 7 similar to metallo-beta- lactamase superfamily 4898 0,0234617 0,2617508 22,7 12,7 1,787 LOC153364 protein hexose-6- phosphate dehydrogenas e (glucose 1- dehydrogenas 549 0,0006443 0,0639658 274,3 153,6 1,786 H6PD e) hydroxyacyl- Coenzyme A dehydrogenas 1094 0,0018295 0,0914332 197,4 110,5 1,786 HADH e CDNA FLJ25559 fis, clone 1206 0,0021493 0,0974403 259,3 145,2 1,786 NA JTH02834

histone cluster 2918 0,0095012 0,1779634 74,1 41,5 1,786 HIST1H2BF 1, H2bf 3613 0,0135055 0,2043768 10 5,6 1,786 SCRN3 secernin 3 Rap guanine nucleotide exchange 4519 0,0203662 0,2464089 39,1 21,9 1,785 RAPGEF3 factor (GEF) 3

non-metastatic cells 1, protein (NM23A) 2827 0,0090616 0,175254 598,6 335,8 1,783 NME1 expressed in RNA binding motif protein 824 0,0011672 0,0773734 246,5 138,3 1,782 RBM35B 35B CDNA FLJ30658 fis, clone DFNES200043 3892 0,0155229 0,2180664 13,9 7,8 1,782 NA 2

G elongation factor, 812 0,0011354 0,0763636 501,4 281,5 1,781 GFM1 mitochondrial 1 cardiolipin 1320 0,0024882 0,1029968 21,9 12,3 1,78 CRLS1 synthase 1 5511 0,028853 0,2861008 249,6 140,2 1,78 NA NA engulfment and cell motility 440 0,0004728 0,0586671 290,2 163,1 1,779 ELMO2 2

chromosome 6 open reading 1413 0,0027501 0,1064131 133,8 75,2 1,779 C6orf57 frame 57 chromosome 14 open reading frame 2174 0,0056371 0,1417702 107,6 60,5 1,779 C14orf100 100 enoyl Coenzyme A hydratase domain 5848 0,0317372 0,2967222 206,7 116,2 1,779 ECHDC1 containing 1 protein phosphatase 1H (PP2C domain 1032 0,001665 0,0879972 9,6 5,4 1,778 PPM1H containing) melanoma inhibitory activity family, 1553 0,0032329 0,1138176 38,4 21,6 1,778 MIA3 member 3 soluble liver antigen/liver pancreas 3003 0,0100292 0,1825996 17,6 9,9 1,778 SLA/LP antigen D-aspartate 4516 0,0203319 0,2461574 57,6 32,4 1,778 DDO oxidase

5126 0,0253146 0,2700109 81,8 46 1,778 ARSD arylsulfatase D PTD016 1361 0,0025939 0,1040748 136,8 77 1,777 LOC51136 protein ST6 beta- galactosamide alpha-2,6- sialyltranferase 2598 0,0079213 0,1666005 398,8 224,4 1,777 ST6GAL1 1 3158 0,0109993 0,1904262 129,2 72,7 1,777 ACTL6A actin-like 6A thyroid adenoma 4836 0,0229139 0,25895 71,1 40 1,777 THADA associated ring finger 5352 0,0273609 0,2794089 177,5 99,9 1,777 RNF170 protein 170 glutathione S- transferase, C- terminal domain 2353 0,0065357 0,1518654 26,1 14,7 1,776 GSTCD containing 2422 0,0068918 0,1555777 26,1 14,7 1,776 PB1 polybromo 1 SPFH domain family, member 7283 0,0469451 0,3524267 84,9 47,8 1,776 SPFH1 1 mitochondrial ribosomal 629 0,0007644 0,0664245 59,1 33,3 1,775 MRPL35 protein L35 heterogeneous nuclear ribonucleoprot 713 0,0009237 0,0708321 482,5 271,8 1,775 HNRPLL ein L-like

F-box and WD- 40 domain 785 0,0010843 0,0755211 221,2 124,6 1,775 FBXW2 protein 2 potassium inwardly- rectifying channel, subfamily J, 6251 0,0359898 0,3147734 54,3 30,6 1,775 KCNJ2 member 2 tetratricopeptid e repeat 2700 0,0083761 0,1695229 365,4 206 1,774 TTC35 domain 35 apolipoprotein B mRNA editing enzyme, catalytic polypeptide- like 3G /// apolipoprotein B mRNA editing enzyme, APOBEC3G catalytic /// polypeptide- 3163 0,0110179 0,1904533 41,7 23,5 1,774 APOBEC3F like 3F thyroid adenoma 4348 0,019045 0,2394102 98,8 55,7 1,774 THADA associated stearoyl-CoA 5082 0,0250374 0,2693664 18,8 10,6 1,774 SCD5 desaturase 5 nudix (nucleoside diphosphate linked moiety X)-type motif 16 5589 0,0294541 0,2881284 31,4 17,7 1,774 NUDT16P pseudogene TIA1 cytotoxic granule- associated RNA binding 7138 0,0452357 0,3464592 14,9 8,4 1,774 TIA1 protein mannosyl (alpha-1,3-)- glycoprotein beta-1,2-N- acetylglucosa minyltransferas 322 0,0003256 0,0549787 1378,4 777,3 1,773 MGAT1 e FLJ12716 749 0,0010018 0,0730677 172,5 97,3 1,773 FLJ12716 protein prostaglandin F2 receptor negative 3556 0,0132218 0,2032908 160,5 90,5 1,773 PTGFRN regulator zinc finger 833 0,001198 0,0786101 10,1 5,7 1,772 ZNF91 protein 91

uncoupling protein 2 (mitochondrial, 1301 0,0024359 0,1023696 3152,1 1778,8 1,772 UCP2 proton carrier) acetyl- Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl- Coenzyme A 3749 0,0143261 0,2089303 1706,2 962,8 1,772 ACAA2 thiolase) SYS1 Golgi- localized integral membrane protein homolog (S. 1548 0,0032116 0,1133907 169,1 95,5 1,771 SYS1 cerevisiae)

Eukaryotic translation initiation factor 4E binding 2017 0,0049562 0,1343033 266,9 150,7 1,771 EIF4EBP2 protein 2 diaphanous homolog 2 5483 0,0285367 0,2845603 127,7 72,1 1,771 DIAPH2 (Drosophila)

fibroblast growth factor receptor 1 (fms- related tyrosine kinase 2, Pfeiffer 5812 0,0313899 0,295293 122,7 69,3 1,771 FGFR1 syndrome) protein tyrosine phosphatase, receptor type, 2622 0,0080395 0,167497 51,5 29,1 1,77 PTPRM M solute carrier family 16, member 5 (monocarboxyli c acid 3299 0,0117858 0,1953285 135,9 76,8 1,77 SLC16A5 transporter 6) CDNA clone IMAGE:481977 7129 0,0451835 0,3464592 20 11,3 1,77 NA 5

chromosome 9 open reading 1064 0,0017441 0,0896228 70,6 39,9 1,769 C9orf41 frame 41 phosphatidic acid phosphatase type 2 domain 4573 0,0208032 0,248724 82,8 46,8 1,769 PPAPDC1B containing 1B SAM domain and HD 1049 0,001693 0,088241 218,2 123,4 1,768 SAMHD1 domain 1 SYS1 Golgi- localized integral membrane protein homolog (S. 2025 0,0050185 0,1353974 258,9 146,4 1,768 SYS1 cerevisiae)

angel homolog 577 0,0006862 0,0650225 128,8 72,9 1,767 ANGEL1 1 (Drosophila)

prolyl 1341 0,0025494 0,1036037 144,2 81,6 1,767 PREP endopeptidase propionyl Coenzyme A carboxylase, beta 534 0,0006288 0,0635709 309,4 175,2 1,766 PCCB polypeptide THO complex 851 0,0012368 0,0791194 82,1 46,5 1,766 THOC2 2 zyg-11 homolog B (C. 566 0,000665 0,064104 434,1 246 1,765 ZYG11B elegans) SUMO/sentrin specific peptidase family member 1133 0,0019616 0,0946254 26,3 14,9 1,765 SENP8 8 ubiquitin specific 1663 0,0035684 0,1172588 143,5 81,3 1,765 USP24 peptidase 24 5102 0,0251918 0,2698517 70,6 40 1,765 IPO4 importin 4

chromosome 7 open reading 1050 0,0016988 0,0884589 81,3 46,1 1,764 C7orf25 frame 25 dihydrolipoami de branched chain transacylase 2718 0,0084943 0,1708071 9,7 5,5 1,764 DBT E2 DNA cross-link repair 1C (PSO2 homolog, S. 2735 0,0085867 0,1716407 12,7 7,2 1,764 DCLRE1C cerevisiae) Zinc finger 4092 0,0170578 0,2279167 9,7 5,5 1,764 ZNF780A protein 780A

carboxylestera se 2 (intestine, 1722 0,0037709 0,1195727 204,5 116 1,763 CES2 liver) staufen, RNA binding protein, homolog 2 1007 0,0015898 0,0863181 50,4 28,6 1,762 STAU2 (Drosophila) Transcribed 1706 0,0037132 0,1189846 11,1 6,3 1,762 NA locus zinc finger 2080 0,0052594 0,1382489 267,3 151,7 1,762 ZNF650 protein 650 X-prolyl aminopeptidas e (aminopeptida se P) 3, 2574 0,0077764 0,1651805 45,1 25,6 1,762 XPNPEP3 putative Transcribed 4201 0,017857 0,2324045 28,9 16,4 1,762 NA locus

solute carrier family 22 (organic cation transporter), 1679 0,0036203 0,1177064 16,2 9,2 1,761 SLC22A16 member 16 intracisternal A particle- promoted 2252 0,0060379 0,1465907 19,9 11,3 1,761 IPP polypeptide HEAT repeat 2286 0,0062113 0,1485449 183 103,9 1,761 HEATR1 containing 1 solute carrier family 25 (carnitine/acylc arnitine translocase), 456 0,0004982 0,0597118 378,2 214,9 1,76 SLC25A20 member 20 similar to 3885 0,0154794 0,2178472 25,5 14,5 1,759 LOC400506 TSG118.1 6451 0,0378284 0,3206089 32,9 18,7 1,759 NA NA 3- hydroxybutyrat e dehydrogenas e, type 1 /// 3- hydroxybutyrat e dehydrogenas 664 0,0008454 0,0695894 41,5 23,6 1,758 BDH1 e, type 1

adaptor-related protein complex 2, 899 0,0013193 0,0802264 362,2 206 1,758 AP2B1 beta 1 subunit aldehyde dehydrogenas e 3 family, 2277 0,0061816 0,1483395 590 335,7 1,758 ALDH3A2 member A2 CDNA FLJ31398 fis, clone NT2NE100017 2479 0,007203 0,1588641 31,1 17,7 1,757 NA 5 abhydrolase domain 4522 0,0204295 0,2469635 702,7 399,9 1,757 ABHD2 containing 2

peroxisome proliferator- activated 354 0,0003608 0,0556372 88,7 50,5 1,756 PPARA receptor alpha adenosine monophosphat e deaminase 2 622 0,0007539 0,0662693 366,5 208,7 1,756 AMPD2 (isoform L) 1980 0,0047863 0,1321225 15,1 8,6 1,756 NA NA phosphatidylin ositol glycan anchor biosynthesis, 3666 0,0138466 0,2065092 79 45 1,756 PIGX class X ankyrin repeat 2818 0,0090237 0,1750784 27,9 15,9 1,755 ANKRD13C domain 13C

aspartyl-tRNA synthetase 2 1366 0,0026179 0,1047831 70,5 40,2 1,754 DARS2 (mitochondrial) 7541 0,0495976 0,3595603 78,6 44,8 1,754 FDX1 ferredoxin 1 Hypothetical protein 3708 0,0141163 0,2080936 56,8 32,4 1,753 LOC728431 LOC728431 hypothetical protein 3799 0,014798 0,212939 59,6 34 1,753 LOC283874 LOC283874 Ribosomal 4368 0,01919 0,2402045 317,4 181,1 1,753 RPL5 protein L5 glucosamine- phosphate N- acetyltransfera 754 0,0010101 0,0732456 76,9 43,9 1,752 GNPNAT1 se 1 2491 0,0072701 0,1595295 25,4 14,5 1,752 NA NA integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, 3416 0,0124003 0,1984223 515,4 294,1 1,752 ITGB1 MSK12) tetratricopeptid e repeat 3719 0,0141693 0,2082838 77,9 44,5 1,751 TTC8 domain 8

Adipose differentiation- 7029 0,0441533 0,3433895 40,8 23,3 1,751 ADFP related protein hypothetical protein 530 0,00062 0,0635709 100,8 57,6 1,75 MGC4562 MGC4562 zinc finger 4112 0,0172124 0,2288456 142,1 81,2 1,75 ZNF720 protein 720 CDNA FLJ46701 fis, clone TRACH301406 6789 0,0416419 0,3353583 23,8 13,6 1,75 NA 3 1740 0,0038269 0,1202504 97,6 55,8 1,749 XPO5 exportin 5 2110 0,0053746 0,1392684 73,3 41,9 1,749 KIAA1704 KIAA1704 solute carrier family 35, 6068 0,0340486 0,3067086 182 104,1 1,748 SLC35F5 member F5 fer-1-like 3, myoferlin (C. 6605 0,0393109 0,3254085 486,6 278,4 1,748 FER1L3 elegans)

1-acylglycerol- 3-phosphate O- acyltransferase 7 (lysophosphati dic acid acyltransferase 6219 0,0356599 0,3135078 159,7 91,4 1,747 AGPAT7 , eta)

Carbohydrate (chondroitin 4) sulfotransferas 985 0,0015368 0,0853041 743,9 426,3 1,745 CHST11 e 11 phosphatidylin ositol glycan anchor biosynthesis, 2157 0,0055802 0,1413783 76,6 43,9 1,745 PIGN class N unc-51-like kinase 2 (C. 3118 0,0107158 0,187877 33,5 19,2 1,745 ULK2 elegans) origin recognition complex, subunit 5-like 7210 0,0460803 0,3494369 116,4 66,7 1,745 ORC5L (yeast)

spermatogene sis associated, 678 0,0008726 0,0701954 70,8 40,6 1,744 SPATS2 serine-rich 2 841 0,0012158 0,0790355 34,7 19,9 1,744 NBN Nibrin Transcribed 5315 0,0270502 0,2782633 84,4 48,4 1,744 NA locus sel-1 suppressor of lin-12-like (C. 696 0,0008988 0,070427 908,6 521,4 1,743 SEL1L elegans) G protein- coupled 771 0,0010631 0,075254 24,4 14 1,743 GPR180 receptor 180 1280 0,0023638 0,1008909 12,2 7 1,743 NA NA Zinc finger CCCH-type 3557 0,0132489 0,2036033 108,6 62,3 1,743 ZC3H13 containing 13 HBV preS1- transactivated 3758 0,0144156 0,209714 181,3 104 1,743 PS1TP4 protein 4 retinoic acid receptor responder (tazarotene 1230 0,0022053 0,0980283 15,5 8,9 1,742 RARRES1 induced) 1 transmembran 1571 0,0032749 0,1139753 92,3 53 1,742 TMEM63A e protein 63A

MRNA; cDNA DKFZp762E13 14 (from clone DKFZp762E13 1940 0,0046081 0,1298257 365,3 209,7 1,742 NA 14) 4051 0,0167878 0,2265369 48,6 27,9 1,742 KIAA1704 KIAA1704

Homo sapiens, clone IMAGE:38666 455 0,0004979 0,0597118 19,5 11,2 1,741 NA 95, mRNA spermatid perinuclear RNA binding 1215 0,0021775 0,097918 19,5 11,2 1,741 STRBP protein

vacuolar protein sorting 13 homolog D 3779 0,0145871 0,2110478 57,8 33,2 1,741 VPS13D (S. cerevisiae) 4913 0,023535 0,2619125 80,2 46,1 1,74 KIAA1841 KIAA1841

Cdc42 guanine nucleotide exchange 82 5,47E-05 0,0360595 46,6 26,8 1,739 ARHGEF9 factor (GEF) 9

Transmembran e 7 superfamily 165 0,0001382 0,0457945 36,7 21,1 1,739 TM7SF3 member 3

chromosome 1 open reading frame 97 /// chromosome 1 open reading 523 0,0006088 0,0635709 63,3 36,4 1,739 C1orf97 frame 97 McKusick- Kaufman 661 0,0008397 0,0693761 237,2 136,4 1,739 MKKS syndrome chromosome 18 open reading frame 1090 0,0018145 0,0908997 60,5 34,8 1,739 C18orf55 55 echinoderm microtubule associated 2432 0,0069237 0,1555957 724,7 416,7 1,739 EML4 protein like 4 protein phosphatase 1K (PP2C domain 2937 0,0096567 0,1796709 60,5 34,8 1,739 PPM1K containing) zinc finger, DHHC-type 5197 0,0260183 0,2737253 76 43,7 1,739 ZDHHC2 containing 2 Transcribed 5312 0,0270111 0,2780181 16 9,2 1,739 NA locus 6211 0,0355687 0,3131088 184,7 106,2 1,739 CALU calumenin Chromosome 21 open reading frame 260 0,0002482 0,0521767 74,4 42,8 1,738 C21orf86 86 putative homeodomain transcription 1265 0,0022906 0,0990028 35,8 20,6 1,738 PHTF1 factor 1 pogo transposable element with 1717 0,0037477 0,1193112 511,8 294,4 1,738 POGK KRAB domain ferredoxin 3717 0,014163 0,2082838 21,9 12,6 1,738 FDXR reductase Solute carrier family 37 (glycerol-3- phosphate transporter), 5376 0,0275561 0,2802511 13,9 8 1,738 SLC37A3 member 3 WD repeat 434 0,0004648 0,0583909 170,7 98,3 1,737 WDR77 domain 77

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal 1188 0,0021037 0,096818 53,5 30,8 1,737 AMMECR1 region, gene 1 deoxyribonucle ase II, 4427 0,0196619 0,2428313 74,5 42,9 1,737 DNASE2 lysosomal

6107 0,0344812 0,3086141 35,6 20,5 1,737 FBXO9 F-box protein 9 dehydrogenas e/reductase (SDR family) 6168 0,0351576 0,3116475 324,4 186,8 1,737 DHRS3 member 3 zinc finger 6081 0,0341613 0,3071068 28,3 16,3 1,736 ZNF2 protein 2 prolylcarboxyp eptidase (angiotensinas 849 0,0012344 0,0791194 1736,1 1000,8 1,735 PRCP e C) PDZ and LIM 1175 0,0020695 0,0961653 17,7 10,2 1,735 PDLIM5 domain 5 de-etiolated homolog 1 2162 0,0055973 0,1415506 43,9 25,3 1,735 DET1 (Arabidopsis)

7- dehydrocholest 3272 0,0116185 0,1940988 85,2 49,1 1,735 DHCR7 erol reductase glutamine and 5257 0,0265474 0,2760755 272,6 157,1 1,735 QSER1 serine rich 1 Phospholipase C, beta 1 (phosphoinositi 5874 0,0319857 0,2977219 22,9 13,2 1,735 PLCB1 de-specific) hypothetical protein 1018 0,0016165 0,0868194 16,3 9,4 1,734 P15RS FLJ10656 small EDRK- rich factor 1A (telomeric) /// similar to small EDRK-rich SERF1A /// factor 1A, 4634 0,021287 0,2511581 61,4 35,4 1,734 LOC728492 telomeric

spastic paraplegia 20, spartin (Troyer 1307 0,0024635 0,1029552 32,4 18,7 1,733 SPG20 syndrome) methyltransfer 1603 0,0033976 0,1157798 56,5 32,6 1,733 METTL8 ase like 8 arginyltransfer 1752 0,003885 0,1210936 79,2 45,7 1,733 ATE1 ase 1 UDP- Gal:betaGlcNA c beta 1,4- galactosyltrans ferase, 1794 0,0040396 0,1231132 13 7,5 1,733 B4GALT6 polypeptide 6

ATPase, Class 1124 0,0019435 0,0944329 128,7 74,3 1,732 ATP9B II, type 9B adenosine deaminase, RNA-specific, B1 (RED1 2336 0,0064165 0,1501586 24,6 14,2 1,732 ADARB1 homolog rat) chromodomain helicase DNA binding protein 3367 0,0122097 0,1982671 262,3 151,5 1,731 CHD1L 1-like transmembran 4523 0,0204301 0,2469635 39,3 22,7 1,731 TMEM19 e protein 19

selenophospha 476 0,0005322 0,0611303 1324,2 765,4 1,73 SEPHS2 te synthetase 2

BET1 homolog 1223 0,0021924 0,0979999 157,3 90,9 1,73 BET1 (S. cerevisiae) hypothetical protein 1306 0,0024621 0,1029552 173 100 1,73 LOC285636 LOC285636 chromosome 10 open reading frame 1606 0,0034036 0,1157798 197,7 114,3 1,73 C10orf61 61 Choline/ethano lamine phosphotransf 2129 0,0054577 0,1401596 10,9 6,3 1,73 CEPT1 erase 1 coiled-coil domain 2871 0,0092558 0,1762664 42,9 24,8 1,73 CCDC76 containing 76 Full length insert cDNA 3189 0,0112082 0,1921632 37,2 21,5 1,73 NA clone YX81F03 WD repeat 3516 0,0130186 0,2023084 43,6 25,2 1,73 WDR4 domain 4 golgi associated PDZ and coiled-coil motif 6979 0,0436434 0,3418002 96 55,5 1,73 GOPC containing

Homo sapiens, clone IMAGE:38510 7142 0,045264 0,3464592 110,2 63,7 1,73 NA 18, mRNA

gamma tubulin ring complex protein (76p 1888 0,0044265 0,128188 82,3 47,6 1,729 76P gene) solute carrier family 7 (cationic amino acid transporter, y+ system), 4395 0,0194672 0,2421773 178,1 103 1,729 SLC7A8 member 8 CDNA clone IMAGE:451345 4644 0,0213774 0,2516816 362,5 209,7 1,729 NA 3 phosphoinositi de-3-kinase, regulatory subunit 1 (p85 5907 0,0323907 0,2997838 808,4 467,5 1,729 PIK3R1 alpha)

Full-length cDNA clone CS0CAP006Y P08 of Thymus of Homo sapiens 3820 0,0149284 0,2136676 66,2 38,3 1,728 NA (human) chloride 4306 0,0186615 0,2369051 113,5 65,7 1,728 CLCN3 channel 3 cardiolipin 400 0,0004294 0,0577884 273,4 158,3 1,727 CRLS1 synthase 1 adducin 3 487 0,0005485 0,0615795 472,1 273,3 1,727 ADD3 (gamma) 1274 0,0023269 0,0998613 27,8 16,1 1,727 NA NA fer-1-like 3, myoferlin (C. 3010 0,0100681 0,1828781 1377,6 797,5 1,727 FER1L3 elegans) Phosphoribosy lglycinamide formyltransfera se, phosphoribosyl glycinamide synthetase, phosphoribosyl aminoimidazol 6912 0,0428079 0,3386172 101,2 58,6 1,727 GART e synthetase zinc finger, DHHC-type 541 0,0006314 0,0635709 14,5 8,4 1,726 ZDHHC21 containing 21 lysophospholip ase 3 (lysosomal phospholipase 2334 0,0064086 0,1501243 228,5 132,4 1,726 LYPLA3 A2) FLJ12716 2823 0,0090557 0,175254 132,7 76,9 1,726 FLJ12716 protein lectin, mannose- 2828 0,0090723 0,1753561 44,7 25,9 1,726 LMAN1 binding, 1 solute carrier family 16, member 5 (monocarboxyli c acid 4232 0,0180825 0,2335758 67,3 39 1,726 SLC16A5 transporter 6) early endosome antigen 1, 1078 0,0017853 0,0905485 69,5 40,3 1,725 EEA1 162kD kelch domain 1968 0,0047198 0,1311255 17,6 10,2 1,725 KLHDC5 containing 5

ninein (GSK3B interacting 4029 0,0166199 0,2255327 264,9 153,6 1,725 NIN protein)

coiled-coil domain 5826 0,0315284 0,2958832 31,4 18,2 1,725 CCDC90B containing 90B leucine rich repeat containing 37, 6090 0,0342705 0,3076306 22,6 13,1 1,725 LRRC37A3 member A3 N- acetyltransfera 6854 0,042203 0,3366308 60,9 35,3 1,725 NAT11 se 11 dehydrogenas e/reductase (SDR family) 7037 0,0442011 0,3434269 379,8 220,2 1,725 DHRS9 member 9 isoleucine- tRNA 770 0,0010628 0,075254 1293,3 750,1 1,724 IARS synthetase SUMO1 activating enzyme 1291 0,0024093 0,102036 199,8 115,9 1,724 SAE1 subunit 1 acyl- Coenzyme A dehydrogenas e, short/branched 1616 0,003434 0,116061 38,1 22,1 1,724 ACADSB chain purinergic receptor P2X, ligand-gated 1799 0,0040609 0,1234184 80,1 46,5 1,723 P2RX5 ion channel, 5

multiple EGF- 5334 0,0272363 0,2791797 27,4 15,9 1,723 MEGF8 like-domains 8 cadherin-like 5615 0,029684 0,2889396 28,6 16,6 1,723 CDH23 23

sialic acid binding Ig-like lectin 5 /// sialic acid binding Ig- 6468 0,0380335 0,321503 64,1 37,2 1,723 SIGLEC5 like lectin 5 ELMO/CED-12 domain 470 0,0005189 0,0602236 101,1 58,7 1,722 ELMOD2 containing 2 Similar to M- phase phosphoprotei 1723 0,0037713 0,1195727 19,8 11,5 1,722 LOC729908 n 10 5-azacytidine 2006 0,0049009 0,1335438 86,8 50,4 1,722 AZI2 induced 2 Serine/threonin 2112 0,0053826 0,1392802 18,6 10,8 1,722 STK38 e kinase 38 hypothetical protein 4312 0,0186934 0,2369837 186 108 1,722 FLJ90757 LOC440465 zinc finger 5314 0,0270415 0,2782262 9,3 5,4 1,722 ZNF223 protein 223

Homo sapiens, clone IMAGE:38666 911 0,0013509 0,0810038 45,6 26,5 1,721 NA 95, mRNA

RAB3 GTPase activating protein subunit 2 (non- 2865 0,0092387 0,176232 206,3 119,9 1,721 RAB3GAP2 catalytic) Ethanolamine 4973 0,0240263 0,264154 299,6 174,1 1,721 ETNK1 kinase 1 Nuclear receptor subfamily 2, group C, 6046 0,0338348 0,3059738 69,2 40,2 1,721 NR2C2 member 2 coiled-coil domain 7534 0,0495476 0,3594767 40,1 23,3 1,721 CCDC66 containing 66 Transcribed 2549 0,0075942 0,1628925 64,5 37,5 1,72 NA locus mitogen- activated protein kinase kinase kinase 6576 0,0390915 0,3250194 86 50 1,72 MAP4K4 kinase 4 aminolevulinat e, delta-, 990 0,0015544 0,0856868 315,5 183,5 1,719 ALAD dehydratase RAB32, member RAS oncogene 1190 0,0021158 0,0969771 503,4 292,8 1,719 RAB32 family isoleucine- tRNA synthetase 2, 1873 0,0043801 0,1278386 658,9 383,3 1,719 IARS2 mitochondrial cytoskeleton associated 2740 0,0086312 0,1722103 140,3 81,6 1,719 CKAP5 protein 5 transmembran 3860 0,0153402 0,2172528 108,3 63 1,719 TMEM48 e protein 48 calcium/calmo dulin- dependent protein kinase (CaM kinase) II 6166 0,0351382 0,3115766 708,5 412,1 1,719 CAMK2D delta lymphocyte cytosolic protein 1 (L- 2446 0,006995 0,156358 2447,9 1425,1 1,718 LCP1 plastin) DENN/MADD domain 3028 0,010169 0,1835023 487,7 283,9 1,718 DENND4C containing 4C GLI pathogenesis- related 1 3066 0,0104335 0,1860573 584,5 340,2 1,718 GLIPR1 (glioma) CDNA FLJ37755 fis, clone BRHIP202376 4050 0,0167857 0,2265369 161,9 94,3 1,717 NA 2 chromosome 10 open reading frame 245 0,00023 0,0510448 90,6 52,8 1,716 C10orf97 97 microsomal glutathione S- 1842 0,0042358 0,1257288 1360,2 792,7 1,716 MGST1 transferase 1

nudix (nucleoside diphosphate linked moiety 2589 0,0078431 0,1656209 24,2 14,1 1,716 NUDT6 X)-type motif 6 5173 0,0257708 0,2723069 50,8 29,6 1,716 NA NA golgi associated, gamma adaptin ear containing, ARF binding 717 0,0009312 0,0708877 60,7 35,4 1,715 GGA2 protein 2 esophageal cancer associated 1562 0,0032569 0,1138946 290,2 169,2 1,715 MGC16824 protein melanoma inhibitory activity family, 597 0,0007243 0,0657513 72,5 42,3 1,714 MIA3 member 3

PTPRF interacting protein, binding protein 1019 0,0016239 0,0871312 10,8 6,3 1,714 PPFIBP1 1 (liprin beta 1) MRNA; cDNA DKFZp686L15 210 (from clone DKFZp686L15 2319 0,0063672 0,1498086 46,1 26,9 1,714 NA 210) 2393 0,0067302 0,153734 24 14 1,714 KIAA1333 KIAA1333 CDNA FLJ36555 fis, clone TRACH200871 5569 0,0293276 0,2878108 19,2 11,2 1,714 NA 6 acyl-CoA synthetase long-chain family member 6207 0,0355131 0,3128208 12 7 1,714 ACSL6 6 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, 721 0,0009375 0,0710699 110 64,2 1,713 SMARCA2 member 2 chromosome 14 open reading frame 1490 0,0029869 0,1095772 49,5 28,9 1,713 C14orf149 149 N- acetylglucosa minidase, alpha- (Sanfilippo 1524 0,0031156 0,1117752 154,2 90 1,713 NAGLU disease IIIB) peroxisomal biogenesis 1586 0,0033277 0,1146762 313 182,7 1,713 PEX14 factor 14 proline synthetase co- transcribed homolog 1909 0,0045111 0,1292008 405,8 236,9 1,713 PROSC (bacterial) calcium/calmo dulin- dependent protein kinase (CaM kinase) II 6095 0,0343654 0,3082737 199,4 116,4 1,713 CAMK2D delta BTB (POZ) domain 2106 0,0053672 0,1392684 771,7 450,8 1,712 BTBD1 containing 1 chromodomain helicase DNA binding protein 4135 0,0173416 0,22922 44,5 26 1,712 CHD9 9 TRIAD3 407 0,000435 0,0577884 45,5 26,6 1,711 TRIAD3 protein

protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta 551 0,0006458 0,0639658 26 15,2 1,711 PPP2R1B isoform Chromosome 12 open reading frame 631 0,0007666 0,0664245 77,7 45,4 1,711 C12orf38 38 hypothetical protein 4490 0,0201882 0,2457406 81,6 47,7 1,711 LOC116236 LOC116236 308 0,0003068 0,0541231 34,2 20 1,71 KIAA1919 KIAA1919

protein kinase, cAMP- dependent, regulatory, type I, alpha (tissue specific 451 0,000491 0,0595242 2623,8 1534,2 1,71 PRKAR1A extinguisher 1) hexosaminidas e B (beta 1074 0,0017766 0,0903205 5884,3 3441,9 1,71 HEXB polypeptide) CCR4 carbon catabolite repression 4- like (S. 1313 0,0024769 0,1029968 37,8 22,1 1,71 CCRN4L cerevisiae)

acetyl- Coenzyme A acyltransferase 1 (peroxisomal 3-oxoacyl- Coenzyme A 1739 0,0038252 0,1202504 636,5 372,2 1,71 ACAA1 thiolase) transmembran 2338 0,0064273 0,1502779 292,9 171,3 1,71 TMEM4 e protein 4 SAC3 domain 5124 0,025305 0,2700109 78,5 45,9 1,71 SAC3D1 containing 1 RNA binding motif, single stranded interacting 1089 0,0018122 0,0908997 647 378,5 1,709 RBMS1 protein 1 translocation 2677 0,0082779 0,1690677 17,6 10,3 1,709 TLOC1 protein 1 peroxisome biogenesis 4403 0,019514 0,2422309 29,9 17,5 1,709 PEX1 factor 1 Transcribed 2539 0,0075546 0,1626759 8,2 4,8 1,708 NA locus CAS1 domain 3686 0,0139718 0,2072458 42,7 25 1,708 CASD1 containing 1 1836 0,0042157 0,1254704 58,9 34,5 1,707 NINJ2 Ninjurin 2

1-acylglycerol- 3-phosphate O- acyltransferase 5 (lysophosphati dic acid acyltransferase 2535 0,0075073 0,1618841 188,4 110,4 1,707 AGPAT5 , epsilon) chromosome 16 open reading frame 3138 0,0108446 0,1889066 406,4 238,1 1,707 C16orf33 33 G protein- coupled receptor associated sorting protein 411 0,0004381 0,0577884 21,5 12,6 1,706 GPRASP2 2 3- hydroxyisobuty rate dehydrogenas 624 0,0007584 0,0664236 290,5 170,3 1,706 HIBADH e dihydrofolate 2196 0,005755 0,1432853 43 25,2 1,706 DHFR reductase prolyl endopeptidase- 5199 0,0260506 0,2739133 75,9 44,5 1,706 PREPL like

ATPase, Class 6480 0,0381272 0,3216773 21,5 12,6 1,706 ATP9A II, type 9A hypothetical protein DKFZp434H DKFZp434H14 6596 0,0392392 0,3251671 14,5 8,5 1,706 1419 19 hairy and enhancer of split 6 5659 0,0301219 0,2910113 157,2 92,2 1,705 HES6 (Drosophila)

chromosome 2 open reading 920 0,00137 0,0814182 381,2 223,7 1,704 C2orf30 frame 30 nemo-like 1973 0,0047437 0,1314555 194,9 114,4 1,704 NLK kinase stress-induced- phosphoprotei n 1 (Hsp70/Hsp90- organizing 6221 0,0356781 0,313567 375,5 220,4 1,704 STIP1 protein) 2@#$%&,5@# $%&- oligoadenylate synthetase 1, 3110 0,010679 0,1877409 560,4 329,1 1,703 OAS1 40/46kDa phosphatidylin ositol glycan anchor biosynthesis, 4998 0,0242812 0,2655318 101 59,3 1,703 PIGX class X bone morphogenetic protein receptor, type II (serine/threoni 453 0,0004946 0,0596959 139,7 82,1 1,702 BMPR2 ne kinase)

uroporphyrinog en III synthase (congenital erythropoietic 1533 0,0031695 0,1129891 240,8 141,6 1,701 UROS porphyria) transmembran 1695 0,0036619 0,1181206 210,2 123,6 1,701 TMEM53 e protein 53 Proteasome (prosome, macropain) 26S subunit, 2986 0,0099297 0,1818173 83,7 49,2 1,701 PSMC2 ATPase, 2 peptidylprolyl isomerase (cyclophilin)- 5267 0,0266538 0,276654 138,5 81,4 1,701 PPIL5 like 5 CDNA clone IMAGE:481429 966 0,0014904 0,0839343 144,5 85 1,7 NA 2 KIAA0746 2282 0,0061938 0,1483988 864,3 508,4 1,7 KIAA0746 protein 6187 0,0352819 0,3117588 10,2 6 1,7 NA NA Protein kinase, cAMP- dependent, regulatory, type 6572 0,0390381 0,3247485 61,2 36 1,7 PRKAR1B I, beta methyltransfer 608 0,000735 0,0657513 133,9 78,8 1,699 METTL1 ase like 1 tubby like 685 0,0008809 0,0701954 67,8 39,9 1,699 TULP4 protein 4 NADH dehydrogenas e (ubiquinone) Fe-S protein 8, 23kDa (NADH- coenzyme Q 973 0,0014937 0,0839343 545,4 321,1 1,699 NDUFS8 reductase) inositol monophosphat ase domain 3375 0,0122543 0,1984192 228,4 134,4 1,699 IMPAD1 containing 1 3625 0,0135924 0,2049724 316,1 186 1,699 NA NA acetoacetyl- CoA 5778 0,0311292 0,2945637 68,3 40,2 1,699 AACS synthetase

Family with sequence 3385 0,0122972 0,1984223 78,3 46,1 1,698 FAM120B similarity 120B

836 0,0012074 0,0789489 1835,8 1081,7 1,697 ACTN1 actinin, alpha 1 scavenger receptor class 4654 0,0214611 0,2520487 442,6 260,8 1,697 SCARB2 B, member 2 hypothetical protein DKFZp667G DKFZp667G21 5099 0,0251486 0,2696607 116,6 68,7 1,697 2110 10 Chloride 524 0,0006093 0,0635709 271,3 160 1,696 CLCN3 channel 3

leucine proline- enriched proteoglycan 1177 0,0020725 0,0961653 240,2 141,6 1,696 LEPRE1 (leprecan) 1 GLI pathogenesis- related 1 2824 0,0090558 0,175254 2248 1325,5 1,696 GLIPR1 (glioma) nudix (nucleoside diphosphate linked moiety X)-type motif 4089 0,0170364 0,2277978 83,1 49 1,696 NUDT16 16 hect domain 4696 0,0217994 0,253808 32,4 19,1 1,696 HERC6 and RLD 6

required for meiotic nuclear division 1 homolog (S. 501 0,0005742 0,0626634 58,3 34,4 1,695 RMND1 cerevisiae) ATG7 autophagy related 7 homolog (S. 796 0,0011043 0,0757259 182,6 107,7 1,695 ATG7 cerevisiae) phosphogluco 997 0,0015675 0,0859576 81,2 47,9 1,695 PGM2 mutase 2 mitochondrial ribosomal 1086 0,0018062 0,0908903 1387,2 818,3 1,695 MRPL3 protein L3 adducin 3 1471 0,0029454 0,1094764 608,3 358,8 1,695 ADD3 (gamma) 4838 0,0229201 0,25895 27,8 16,4 1,695 FMNL3 formin-like 3 Transcribed 3311 0,0118841 0,196206 8,3 4,9 1,694 NA locus 3667 0,0138605 0,2066602 39,8 23,5 1,694 PPHLN1 periphilin 1 AHA1, activator of heat shock 90kDa protein ATPase homolog 2 3943 0,0158965 0,2204264 274,5 162,1 1,693 AHSA2 (yeast)

angiogenic factor with G patch and FHA 149 0,0001233 0,0449393 265,1 156,7 1,692 AGGF1 domains 1 210 0,0001879 0,0483249 165,5 97,8 1,692 KIAA1815 KIAA1815 CDNA FLJ30026 fis, clone 3NB69200112 1906 0,0044983 0,129037 13,2 7,8 1,692 NA 3 PTD016 1931 0,0045767 0,1294851 361 213,3 1,692 LOC51136 protein jagged 1 (Alagille 2794 0,0089127 0,1744101 24,7 14,6 1,692 JAG1 syndrome)

chromosome 5 open reading 235 0,0002101 0,0488818 15,9 9,4 1,691 C5orf24 frame 24

chromosome 3 open reading 588 0,0007104 0,0657513 43,8 25,9 1,691 C3orf23 frame 23 mitochondrial ribosomal protein L34 /// mitochondrial ribosomal 1053 0,001707 0,0886327 309,5 183 1,691 MRPL34 protein L34 transmembran 1079 0,0017887 0,090558 107,2 63,4 1,691 TMEM19 e protein 19 sphingosine-1- phosphate 2367 0,0066145 0,1527874 25,2 14,9 1,691 SGPL1 lyase 1 CDNA clone IMAGE:451345 3081 0,0105491 0,1872029 98,2 58,1 1,69 NA 3

tRNA nucleotidyl transferase, 3904 0,0156154 0,2186258 47,3 28 1,689 TRNT1 CCA-adding, 1

4839 0,0229284 0,25895 40,7 24,1 1,689 FBXO4 F-box protein 4 hexose-6- phosphate dehydrogenas e (glucose 1- dehydrogenas 5106 0,0252013 0,2698517 144,2 85,4 1,689 H6PD e) neuropilin (NRP) and tolloid (TLL)- 580 0,0006977 0,0657513 99,6 59 1,688 NETO2 like 2 phosphoinositi de-3-kinase, class 2, alpha 1339 0,0025481 0,1036037 56,9 33,7 1,688 PIK3C2A polypeptide gamma- glutamyl 1534 0,0031701 0,1129891 84,9 50,3 1,688 GGCX carboxylase isoprenylcystei ne carboxyl methyltransfer 2864 0,0092355 0,176232 104,3 61,8 1,688 ICMT ase DIP2 disco- interacting protein 2 homolog C 3050 0,0103245 0,1850794 13,5 8 1,688 DIP2C (Drosophila)

transmembran e 7 superfamily 2072 0,0052142 0,1375763 32,9 19,5 1,687 TM7SF3 member 3 ankyrin repeat and FYVE domain 2375 0,0066428 0,1528714 36,1 21,4 1,687 ANKFY1 containing 1 chromosome 16 open reading frame 4340 0,0189567 0,2387819 103,9 61,6 1,687 C16orf24 24 fatty acid 5401 0,0278418 0,2818222 45,2 26,8 1,687 FASN synthase zinc finger 1953 0,0046522 0,1301763 14,5 8,6 1,686 ZNF763 protein 763 solute carrier family 26 (sulfate transporter), 4099 0,0171218 0,2282885 162,9 96,6 1,686 SLC26A2 member 2 src kinase associated phosphoprotei 343 0,0003482 0,0552439 216,9 128,7 1,685 SKAP2 n 2 HERPUD family member 4584 0,0208719 0,2489466 15 8,9 1,685 HERPUD2 2 hypothetical protein 5128 0,0253483 0,2702649 9,1 5,4 1,685 LOC729680 LOC729680

FK506 binding protein 1A, 1409 0,0027437 0,1063878 1247 740,3 1,684 FKBP1A 12kDa transmembran 2135 0,0054821 0,1403905 482,4 286,5 1,684 TMEM30A e protein 30A signal recognition particle receptor, B 1956 0,004662 0,1303143 116,3 69,1 1,683 SRPRB subunit DNA polymerase- transactivated 2873 0,0092704 0,1764162 445,6 264,7 1,683 DNAPTP6 protein 6 chromosome 16 open reading frame 3059 0,0103937 0,1857717 83,3 49,5 1,683 C16orf57 57

solute carrier family 8 (sodium/calciu m exchanger), 3109 0,0106706 0,1876536 210,7 125,2 1,683 SLC8A1 member 1

suppression of tumorigenicity 14 (colon 3985 0,0162384 0,2227759 686 407,5 1,683 ST14 carcinoma) mixed lineage kinase domain- 4751 0,0222189 0,2556974 293,9 174,6 1,683 MLKL like transcription factor B1, 5253 0,026535 0,2760755 88,2 52,4 1,683 TFB1M mitochondrial dihydrolipoami de branched chain transacylase 6574 0,0390786 0,325011 31,3 18,6 1,683 DBT E2 sorting nexin 303 0,0002981 0,0537908 91,6 54,5 1,681 SNX19 19 pyrroline-5- carboxylate reductase family, member 516 0,000597 0,06322 75,8 45,1 1,681 PYCR2 2 DnaJ (Hsp40) homolog, subfamily C, 1385 0,0026651 0,1051826 300 178,5 1,681 DNAJC13 member 13 retinol dehydrogenas e 11 (all- trans/9-cis/11- 2474 0,0071827 0,1587254 903 537,1 1,681 RDH11 cis) ankyrin repeat and sterile alpha motif domain 3321 0,0119398 0,1965014 166,3 98,9 1,681 ANKS1A containing 1A major histocompatibili ty complex, 3905 0,015616 0,2186258 208,8 124,2 1,681 MR1 class I-related ubiquitin specific 5177 0,0257954 0,2724287 119 70,8 1,681 USP30 peptidase 30 Hypothetical protein similar to KIAA0187 6158 0,0350503 0,3111664 86,9 51,7 1,681 LOC96610 gene product chromosome 12 open reading frame 1311 0,0024741 0,1029968 132,2 78,7 1,68 C12orf4 4 UEV and lactate/malate dehyrogenase 2121 0,0054133 0,1395437 91,4 54,4 1,68 UEVLD domains chromosome 12 open reading frame 2312 0,0063352 0,149757 33,1 19,7 1,68 C12orf46 46 F-box protein 38 /// F-box 2694 0,0083632 0,1695229 329,1 195,9 1,68 FBXO38 protein 38 farnesyltransfe rase, CAAX 1219 0,0021849 0,097918 22,5 13,4 1,679 FNTB box, beta tumor protein p53 (Li- Fraumeni 1535 0,0031728 0,1130116 31,9 19 1,679 TP53 syndrome) suppressor of variegation 4- 20 homolog 1 4941 0,0237531 0,2628417 31,4 18,7 1,679 SUV420H1 (Drosophila) MMS19-like (MET18 homolog, S. 5554 0,0292115 0,2875171 175,1 104,3 1,679 MMS19L cerevisiae) glucosamine (N-acetyl)-6- sulfatase (Sanfilippo 324 0,0003258 0,0549787 1628,2 970,6 1,678 GNS disease IIID) 650 0,0008183 0,0688316 399,5 238,1 1,678 PHB prohibitin 3162 0,0110141 0,1904478 513,9 306,2 1,678 PEPD peptidase D

polycystic kidney disease 2 (autosomal 3279 0,011664 0,1944404 212,3 126,5 1,678 PKD2 dominant) succinate-CoA ligase, ADP- forming, beta 3677 0,0139187 0,2069266 372,3 221,9 1,678 SUCLA2 subunit nucleolar complex associated 3 homolog (S. 4504 0,0202744 0,2460654 86,6 51,6 1,678 NOC3L cerevisiae) dihydrolipoami de S- acetyltransfera se (E2 component of pyruvate dehydrogenas 2076 0,0052336 0,1378358 109,5 65,3 1,677 DLAT e complex) MORN repeat 5535 0,029035 0,2867964 85 50,7 1,677 MORN2 containing 2 hypothetical protein 1002 0,0015753 0,0859576 232,3 138,6 1,676 LOC137886 LOC137886

glycerol kinase 1149 0,0019956 0,0949348 17,6 10,5 1,676 GK5 5 (putative)

mitochondrial trans-2-enoyl- 1415 0,0027569 0,1065236 58,5 34,9 1,676 MECR CoA reductase solute carrier family 7 (cationic amino acid transporter, y+ system), 4535 0,020526 0,2474662 397,3 237 1,676 SLC7A8 member 8 Echinoderm microtubule associated 6994 0,0437372 0,3419118 36,2 21,6 1,676 EML4 protein like 4 RNA binding motif, single stranded interacting 3619 0,0135557 0,2047963 63,8 38,1 1,675 RBMS1 protein 1 mitogen- activated protein kinase kinase kinase 7 interacting 6590 0,039208 0,3251671 292,2 174,4 1,675 MAP3K7IP2 protein 2 SH3 and PX 877 0,0012708 0,0792042 7,7 4,6 1,674 SH3PXD2A domains 2A Hypothetical 1929 0,0045722 0,1294851 7,2 4,3 1,674 LOC613266 LOC613266 Transcribed 4949 0,0238201 0,263157 152,8 91,3 1,674 NA locus NODAL modulator 1 /// NODAL NOMO1 /// modulator 2 /// NOMO2 /// NODAL 613 0,0007397 0,0657513 390,5 233,4 1,673 NOMO3 modulator 3 hypothetical protein 1974 0,0047567 0,131749 167 99,8 1,673 FLJ20489 FLJ20489 zinc finger protein 161 homolog 3044 0,0102665 0,1844024 107,1 64 1,673 ZFP161 (mouse) survival of motor neuron protein interacting 3866 0,0153752 0,2174441 16,9 10,1 1,673 SIP1 protein 1

chromosome 6 open reading 5154 0,0256614 0,2722229 84,5 50,5 1,673 C6orf203 frame 203 adducin 3 890 0,0012989 0,0797948 1227,5 734,2 1,672 ADD3 (gamma) isovaleryl Coenzyme A dehydrogenas 1986 0,0048187 0,1326598 116,4 69,6 1,672 IVD e chromosome 12 open reading frame 2000 0,004882 0,1334529 38,3 22,9 1,672 C12orf24 24 tetratricopeptid e repeat 2140 0,0055087 0,1407224 92,3 55,2 1,672 TTC5 domain 5 chromodomain helicase DNA binding protein 5354 0,0273662 0,2794089 773,3 462,4 1,672 CHD1L 1-like RAD52 homolog (S. 7406 0,0481516 0,3554805 9,7 5,8 1,672 RAD52 cerevisiae) hypothetical protein 807 0,0011276 0,0763495 166,9 99,9 1,671 FLJ90013 FLJ90013 1601 0,0033931 0,1157798 98,9 59,2 1,671 KIAA0329 KIAA0329 pericentriolar material 1 /// MCM3 minichromoso me maintenance deficient 3 (S. cerevisiae) PCM1 /// associated 2530 0,0074747 0,1615084 11,7 7 1,671 MCM3AP protein coiled-coil domain 2746 0,0086573 0,1723467 212,1 126,9 1,671 CCDC50 containing 50 Full-length cDNA clone CS0DF014YA2 2 of Fetal brain of Homo sapiens 4291 0,0185769 0,2366142 59 35,3 1,671 NA (human)

fibronectin type III domain 6665 0,0401116 0,3290236 325,1 194,5 1,671 FNDC3A containing 3A osteopetrosis associated transmembran 1560 0,0032563 0,1138946 66,3 39,7 1,67 OSTM1 e protein 1 origin recognition complex, subunit 5-like 1801 0,0040746 0,1236973 17,7 10,6 1,67 ORC5L (yeast)

peroxisome proliferator- activated 2727 0,0085309 0,1709856 37,4 22,4 1,67 PPARA receptor alpha mitochondrial ribosomal 2814 0,009015 0,1750784 90 53,9 1,67 MRPS9 protein S9

chromosome 7 open reading 3092 0,0106096 0,1874018 30,4 18,2 1,67 C7orf25 frame 25 XRCC6 binding protein 3486 0,0128059 0,2007817 60,3 36,1 1,67 XRCC6BP1 1 low density lipoprotein receptor adaptor protein 3646 0,0136932 0,2053417 91,5 54,8 1,67 LDLRAP1 1 troponin I type 2 (skeletal, 7239 0,0464218 0,3505808 44,6 26,7 1,67 TNNI2 fast) adenylate 3343 0,0120803 0,1975742 80,1 48 1,669 AK3 kinase 3 hypothetical protein 4936 0,0237227 0,2627712 87,6 52,5 1,669 HSPC268 HSPC268 euchromatic histone-lysine N- methyltransfer 5641 0,0298821 0,2896302 160,2 96 1,669 EHMT2 ase 2 phosphogluco 1350 0,0025619 0,1036037 667,7 400,2 1,668 PGM2 mutase 2 CDNA FLJ40810 fis, clone TRACH200974 1775 0,0039671 0,1221979 36,7 22 1,668 NA 3 eukaryotic translation initiation factor 2073 0,0052162 0,1375763 224,8 134,8 1,668 EIF2C1 2C, 1 Sel-1 suppressor of lin-12-like (C. 3004 0,0100355 0,1826356 320,1 191,9 1,668 SEL1L elegans) vacuolar protein sorting 13 homolog B 7225 0,0462344 0,3498776 175,1 105 1,668 VPS13B (yeast) zinc finger 1913 0,0045254 0,1293195 80,5 48,3 1,667 ZNF175 protein 175 cadherin-like 6780 0,041531 0,3349126 50,5 30,3 1,667 CDH23 23 HEAT repeat 449 0,0004902 0,0595242 225,3 135,2 1,666 HEATR2 containing 2 vacuolar protein sorting 35 homolog (S. 806 0,001123 0,0761787 907,8 544,9 1,666 VPS35 cerevisiae) 1416 0,0027588 0,1065236 691,3 414,9 1,666 RSNL2 restin-like 2 aldo-keto reductase family 1, member A1 (aldehyde 1622 0,0034509 0,1161645 1570,4 942,5 1,666 AKR1A1 reductase) tumor suppressing subtransferabl 2879 0,0093028 0,1765671 141,8 85,1 1,666 TSSC1 e candidate 1 beta-1,3-N- acetylgalactos aminyltransfer 5322 0,027113 0,2784666 194,7 116,9 1,666 B3GALNT2 ase 2 RNA binding motif, single stranded interacting 1517 0,0030932 0,1113787 646,6 388,4 1,665 RBMS1 protein 1 CDNA FLJ33091 fis, clone TRACH200066 2237 0,0059618 0,1456681 179,3 107,7 1,665 NA 0 N- acylaminoacyl- peptide 3082 0,0105539 0,18721 267,9 160,9 1,665 APEH hydrolase Echinoderm microtubule associated 4387 0,019417 0,2419428 56,6 34 1,665 EML4 protein like 4 zinc finger 6568 0,0389907 0,3245762 71,1 42,7 1,665 ZNF512 protein 512 nicotinamide nucleotide adenylyltransfe 1302 0,0024427 0,1025765 23,8 14,3 1,664 NMNAT1 rase 1 ATPase type 2063 0,0051755 0,1371645 475,6 285,8 1,664 ATP13A1 13A1

transmembran 2320 0,0063678 0,1498086 20,8 12,5 1,664 TMEM177 e protein 177

chromosome 6 open reading frame 125 /// chromosome 6 open reading 2390 0,0067259 0,153734 418 251,2 1,664 C6orf125 frame 125 transmembran 2722 0,0085111 0,1709568 263,3 158,2 1,664 TMEM19 e protein 19 zinc finger CCCH-type 3249 0,0115043 0,1935848 200,2 120,3 1,664 ZC3H14 containing 14 F-box protein 817 0,0011486 0,0767723 33,6 20,2 1,663 FBXO22 22 prenyl (decaprenyl) diphosphate synthase, 1047 0,0016922 0,088241 110,9 66,7 1,663 PDSS1 subunit 1 2148 0,0055481 0,1412208 17,3 10,4 1,663 KIAA0467 KIAA0467 nicotinamide nucleotide adenylyltransfe 2420 0,0068849 0,1555358 14,3 8,6 1,663 NMNAT1 rase 1

acetyl- Coenzyme A acyltransferase 1 (peroxisomal 3-oxoacyl- Coenzyme A 3566 0,0132831 0,2036605 213,7 128,5 1,663 ACAA1 thiolase) Chloride 4117 0,0172403 0,2288456 15,8 9,5 1,663 CLCN3 channel 3 peroxisomal biogenesis 1991 0,0048426 0,1329217 45 27,1 1,661 PEX3 factor 3 Transcribed 3864 0,0153583 0,2173176 19,1 11,5 1,661 NA locus

Oxysterol binding protein- 5632 0,0298201 0,2894911 10,3 6,2 1,661 OSBPL1A like 1A zinc finger protein 106 homolog 204 0,0001823 0,0483249 341,6 205,8 1,66 ZFP106 (mouse) Solute carrier family 2 (facilitated glucose transporter), member 3 1864 0,0043121 0,1264829 403,1 242,8 1,66 SLC2A3P1 pseudogene 1 4- aminobutyrate aminotransfera 2301 0,0062721 0,1490339 139,9 84,3 1,66 ABAT se coiled-coil domain 4931 0,0236782 0,2625442 35,2 21,2 1,66 CCDC99 containing 99 transcription factor B1, 3317 0,0119142 0,196385 81,8 49,3 1,659 TFB1M mitochondrial protein tyrosine phosphatase, non-receptor type 11 (Noonan 5622 0,0297288 0,2891181 223,3 134,6 1,659 PTPN11 syndrome 1)

chromosome 9 open reading 6045 0,033833 0,3059738 105,7 63,7 1,659 C9orf64 frame 64 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; 6259 0,0360444 0,314863 185,8 112 1,659 PSME3 Ki) nucleoporin 6436 0,0377094 0,3201776 83,3 50,2 1,659 NUP210 210kDa exocyst complex 1058 0,0017247 0,0891285 111,4 67,2 1,658 EXOC5 component 5 dehydrogenas e/reductase (SDR family) X- 1846 0,004248 0,1257495 48,4 29,2 1,658 DHRSX linked DKFZP564O DKFZP564O0 1916 0,0045318 0,1293195 32,5 19,6 1,658 0823 823 protein ATP citrate 3047 0,0103042 0,1848973 219,9 132,6 1,658 ACLY lyase transmembran 3260 0,0115509 0,1936505 207,8 125,3 1,658 TMEM53 e protein 53 jagged 1 (Alagille 4316 0,0187238 0,2370955 315,1 190 1,658 JAG1 syndrome) chromosome 14 open reading frame 690 0,0008889 0,070427 502 303 1,657 C14orf108 108 Nicotinamide nucleotide transhydrogen 2901 0,00939 0,1769729 11,1 6,7 1,657 NNT ase poly (ADP- ribose) polymerase family, member 3055 0,0103763 0,1857035 1080,2 652 1,657 PARP4 4 ribose 5- phosphate isomerase A (ribose 5- phosphate 5342 0,0272995 0,2793774 274,4 165,6 1,657 RPIA epimerase)

UDP-N-acetyl- alpha-D- galactosamine: polypeptide N- acetylgalactos aminyltransfer ase 1 (GalNAc- 2183 0,0056979 0,1426225 545,7 329,5 1,656 GALNT1 T1) 2649 0,0081399 0,1680064 15,4 9,3 1,656 NA NA F-box and leucine-rich repeat protein 3682 0,013941 0,2070136 31,3 18,9 1,656 FBXL20 20 catenin (cadherin- associated protein), alpha- 4580 0,0208412 0,2487975 1655,1 999,2 1,656 CTNNAL1 like 1 ring finger 5059 0,0248102 0,2680447 352,5 212,8 1,656 RNF146 protein 146

fibroblast growth factor receptor 1 (fms- related tyrosine kinase 2, Pfeiffer 7027 0,0441188 0,3432753 54 32,6 1,656 FGFR1 syndrome) chromatin modifying 374 0,0003984 0,0577756 305,7 184,7 1,655 CHMP4A protein 4A

synaptojanin 2 693 0,0008961 0,070427 121,3 73,3 1,655 SYNJ2BP binding protein

CGG triplet repeat binding protein 1 /// hypothetical protein CGGBP1 /// LOC728397 /// LOC728397 hypothetical /// protein 2099 0,005329 0,1388104 682,5 412,3 1,655 LOC730652 LOC730652 oxysterol binding protein- 2646 0,0081293 0,1679779 655,9 396,2 1,655 OSBPL11 like 11

suppression of tumorigenicity 18 (breast carcinoma) (zinc finger 3429 0,0125215 0,1996243 9,6 5,8 1,655 ST18 protein) pyruvate dehydrogenas e (lipoamide) 3699 0,0140379 0,2074945 1560,8 942,8 1,655 PDHB beta WD repeat 4113 0,0172173 0,2288456 305,9 184,8 1,655 WDR68 domain 68 peroxisomal biogenesis 4440 0,0197626 0,2433604 62,4 37,7 1,655 PEX6 factor 6 Family with sequence similarity 98, 242 0,0002258 0,0508275 190,1 114,9 1,654 FAM98B member B CDNA: FLJ21268 fis, clone 1111 0,0018881 0,092918 47,3 28,6 1,654 NA COL01718 HEAT repeat 1115 0,0019073 0,0935261 152,7 92,3 1,654 HEATR2 containing 2 chromosome 11 open reading frame 1269 0,0023048 0,0993026 76,9 46,5 1,654 C11orf1 1 Zinc finger 1506 0,0030571 0,1109355 43 26 1,654 ZNF714 protein 714 hippocalcin- 4719 0,0219556 0,2543476 436 263,6 1,654 HPCAL1 like 1 alkB, alkylation repair homolog 1163 0,002031 0,0954208 133,9 81 1,653 ALKBH3 3 (E. coli)

guanine nucleotide binding protein- like 3 1273 0,0023243 0,099828 74,4 45 1,653 GNL3L (nucleolar)-like 2007 0,0049021 0,1335438 88,6 53,6 1,653 NA PRO0633 epidermal growth factor receptor pathway 6277 0,0362445 0,315703 187,4 113,4 1,653 EPS15 substrate 15 reticulon 4 interacting protein 1 /// reticulon 4 interacting 801 0,0011094 0,0757259 65,4 39,6 1,652 RTN4IP1 protein 1 BRCA1/BRCA 2-containing complex, 3199 0,011296 0,1929329 234,6 142 1,652 BRCC3 subunit 3 G-rich RNA sequence binding factor 4791 0,0225997 0,2578256 34,7 21 1,652 GRSF1 1 phenazine biosynthesis- like protein domain 5341 0,027297 0,2793774 22,3 13,5 1,652 PBLD containing RNA binding motif, single stranded interacting 947 0,0014319 0,0826707 673,6 408 1,651 RBMS1 protein 1 mutL homolog 2559 0,0076378 0,1631875 50,7 30,7 1,651 MLH3 3 (E. coli) hypothetical protein 2902 0,0093944 0,1769948 59,6 36,1 1,651 MGC2408 MGC2408 ATPase, H+ transporting, lysosomal accessory 1685 0,0036352 0,1177064 1781,3 1079,8 1,65 ATP6AP1 protein 1 Rho-related BTB domain 1884 0,0044095 0,1279192 47,2 28,6 1,65 RHOBTB2 containing 2 secretory carrier membrane 2383 0,0066837 0,1533493 36,8 22,3 1,65 SCAMP1 protein 1 zinc finger 6553 0,038804 0,3237359 83,3 50,5 1,65 ZNF232 protein 232 zinc finger 7448 0,0485823 0,3566377 47,2 28,6 1,65 ZNF789 protein 789 hypothetical protein 2010 0,0049289 0,1340734 24,4 14,8 1,649 LOC283012 LOC283012 2666 0,0082316 0,1688157 509,9 309,3 1,649 ATXN1 ataxin 1 vacuolar protein sorting 8 homolog (S. 5014 0,0244438 0,2665466 193,8 117,5 1,649 VPS8 cerevisiae)

zinc fingers and 1088 0,0018091 0,0908997 20,1 12,2 1,648 ZHX3 homeoboxes 3 phosphatidylet hanolamine binding protein 2929 0,0096047 0,1792888 553,7 336 1,648 PEBP1 1

Full-length cDNA clone CS0DB009YL2 0 of Neuroblastoma Cot 10- normalized of Homo sapiens 3934 0,0158145 0,219791 38,4 23,3 1,648 NA (human) phospholipase 4740 0,0221202 0,2551219 20,6 12,5 1,648 PLCL1 C-like 1 Dicer1, Dcr-1 homolog 6405 0,037342 0,3187082 894,2 542,5 1,648 DICER1 (Drosophila) DNA cross-link repair 1C (PSO2 homolog, S. 6613 0,039439 0,3260528 57,5 34,9 1,648 DCLRE1C cerevisiae) caspase 6, apoptosis- related cysteine 7333 0,0474256 0,3536063 145,2 88,1 1,648 CASP6 peptidase

chromosome 3 open reading 555 0,0006516 0,0640787 236,3 143,5 1,647 C3orf63 frame 63 quinoid dihydropteridin 2026 0,0050246 0,1353974 354 214,9 1,647 QDPR e reductase cornichon homolog 4 3824 0,0150092 0,2145683 50,9 30,9 1,647 CNIH4 (Drosophila) hydroxysteroid (17-beta) dehydrogenas 1194 0,0021178 0,0969771 2104,1 1278 1,646 HSD17B4 e 4 HIG1 domain family, member 2966 0,0098068 0,1807168 1054,1 640,5 1,646 HIGD1A 1A

chromosome 5 open reading 3641 0,0136764 0,2053028 94,8 57,6 1,646 C5orf3 frame 3 adenylate 3773 0,014554 0,2108775 933,5 567 1,646 AK3 kinase 3 hypothetical protein 5957 0,0328707 0,3016964 94,8 57,6 1,646 LOC130355 LOC130355 CDNA clone IMAGE:526121 2926 0,0095777 0,1789681 97,4 59,2 1,645 NA 3

caspase recruitment domain family, 4943 0,0237793 0,2629906 97,4 59,2 1,645 CARD8 member 8 Nedd4 family interacting 6201 0,0354489 0,3125236 15,3 9,3 1,645 NDFIP2 protein 2

UDP-N-acetyl- alpha-D- galactosamine: polypeptide N- acetylgalactos aminyltransfer ase 1 (GalNAc- 1584 0,0033153 0,1144344 433,7 263,8 1,644 GALNT1 T1)

1609 0,0034121 0,1158906 38,8 23,6 1,644 FBXO3 F-box protein 3 cleavage stimulation factor, 3@#$%& pre- RNA, subunit 2, 64kDa, tau 1882 0,0044036 0,1279192 88,3 53,7 1,644 CSTF2T variant HLA complex 2052 0,0051336 0,1367834 17,1 10,4 1,644 HCG18 group 18 Dehydrogenas e/reductase (SDR family) 2113 0,0053827 0,1392802 60,5 36,8 1,644 DHRS3 member 3

Full-length cDNA clone CS0DK012YA1 5 of HeLa cells Cot 25- normalized of Homo sapiens 3975 0,0161494 0,2220979 26,3 16 1,644 NA (human) Similar to RP11- RIKEN cDNA 5186 0,0259421 0,273454 74,8 45,5 1,644 50D16.3 8030451K01 solute carrier family 35, member E2 /// similar to solute carrier SLC35E2 /// family 35, 6175 0,0352195 0,3117492 303,2 184,4 1,644 LOC728661 member E2 CDNA FLJ14756 fis, clone NT2RP300319 3, moderately similar to ZINC FINGER 305 0,0003009 0,05394 53,9 32,8 1,643 NA PROTEIN 135

CDNA FLJ31593 fis, clone 2182 0,0056923 0,1426225 251,6 153,1 1,643 NA NT2RI2002481

P450 (cytochrome) 1446 0,0028536 0,107898 559,9 341 1,642 POR oxidoreductase signal peptidase complex subunit 3 homolog (S. 1448 0,0028592 0,1079605 149,4 91 1,642 SPCS3 cerevisiae)

NADH dehydrogenas e (ubiquinone) 1 alpha subcomplex, assembly 1551 0,0032182 0,1133907 351,9 214,3 1,642 NDUFAF1 factor 1 pantothenate 3906 0,0156187 0,2186258 56,5 34,4 1,642 PANK3 kinase 3

chromosome 7 open reading 3977 0,0161631 0,2221856 176,7 107,6 1,642 C7orf49 frame 49 HLA complex 4002 0,0164067 0,2240719 13,3 8,1 1,642 HCG11 group 11 signal recognition particle receptor, B 248 0,0002327 0,0511178 384,8 234,5 1,641 SRPRB subunit

sphingosine-1- phosphate 4718 0,0219489 0,2543476 309,9 188,8 1,641 SGPP1 phosphatase 1 palladin, cytoskeletal associated 5316 0,0270679 0,2783798 541,4 330 1,641 PALLD protein lymphocyte 2720 0,0084974 0,1708071 57,9 35,3 1,64 LY9 antigen 9 5273 0,0266861 0,276654 41 25 1,64 RBKS ribokinase

tryptophan rich 742 0,0009836 0,0724775 310,5 189,5 1,639 WRB basic protein Src homology 2 domain containing adaptor protein B /// chromosome 9 SHB /// open reading 927 0,001391 0,082042 753,7 459,8 1,639 C9orf105 frame 105 2295 0,0062571 0,1489073 202,4 123,5 1,639 NA NA CSE1 chromosome segregation 1- 4160 0,0175584 0,2307663 83,4 50,9 1,639 CSE1L like (yeast) zinc finger 4356 0,0191026 0,239632 60,3 36,8 1,639 ZNF567 protein 567 5024 0,0245306 0,2669076 19,5 11,9 1,639 CCNG2 Cyclin G2 solute carrier family 25, member 13 6047 0,0338428 0,3059911 153,7 93,8 1,639 SLC25A13 (citrin) NODAL 422 0,0004489 0,0577884 1310,5 800 1,638 NOMO2 modulator 2

methylthioaden osine 762 0,0010382 0,0744239 9,5 5,8 1,638 MTAP phosphorylase DNA (cytosine- 5-)- methyltransfer 2731 0,0085589 0,1712917 113,7 69,4 1,638 DNMT3A ase 3 alpha opioid receptor, 4397 0,0194891 0,2422309 116,3 71 1,638 OPRS1 sigma 1

transmembran 1105 0,0018639 0,0922251 1026,7 627 1,637 TMEM147 e protein 147 ornithine decarboxylase 1613 0,0034273 0,116061 584,1 356,8 1,637 ODC1 1 Endothelial PAS domain 2279 0,0061847 0,1483395 13,1 8 1,637 EPAS1 protein 1 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; 3512 0,0129858 0,2021636 123,4 75,4 1,637 PSME3 Ki) zinc finger 4304 0,0186503 0,2368945 49,6 30,3 1,637 ZNF561 protein 561 6748 0,0411848 0,3335815 291,6 178,1 1,637 KIAA0372 KIAA0372 heparan sulfate 2-O- sulfotransferas 1030 0,0016627 0,0879972 149,5 91,4 1,636 HS2ST1 e 1 Sec23 homolog B (S. 1068 0,0017622 0,0902138 514 314,2 1,636 SEC23B cerevisiae) UDP-N-acetyl- alpha-D- galactosamine: polypeptide N- acetylgalactos aminyltransfer ase 10 1545 0,0032033 0,1132377 62,5 38,2 1,636 GALNT10 (GalNAc-T10) chromosome 14 open reading frame 3273 0,0116193 0,1940988 1064,7 650,7 1,636 C14orf119 119 reticulon 4 interacting 3550 0,0131726 0,2028766 55,3 33,8 1,636 RTN4IP1 protein 1 chromodomain helicase DNA binding protein 3918 0,0156941 0,2190084 384,4 235 1,636 CHD9 9 4391 0,019434 0,2419481 42,7 26,1 1,636 GPHN gephyrin interferon (alpha, beta and omega) 5136 0,0254762 0,2712055 221,7 135,5 1,636 IFNAR1 receptor 1 mitochondrial ribosomal 875 0,0012662 0,0791194 144,5 88,4 1,635 MRPS27 protein S27 kelch repeat and BTB (POZ) domain 4694 0,0217886 0,2537903 8,5 5,2 1,635 KBTBD6 containing 6 hypoxia up- 1661 0,0035643 0,1172588 245,7 150,4 1,634 HYOU1 regulated 1 threonyl-tRNA synthetase-like 2023 0,0050079 0,135347 79,4 48,6 1,634 TARSL1 1 NLR family 2028 0,0050259 0,1353974 159,3 97,5 1,634 NLRX1 member X1 timeless homolog 3488 0,0128089 0,2007817 45,6 27,9 1,634 TIMELESS (Drosophila) zinc finger 5109 0,025224 0,2698832 85,8 52,5 1,634 ZNF600 protein 600 hypothetical protein 5580 0,0294042 0,2880914 42,8 26,2 1,634 LOC144233 LOC144233 5859 0,0318437 0,297159 103,6 63,4 1,634 RSNL2 Restin-like 2 integrator complex 6088 0,0342631 0,3076306 80,7 49,4 1,634 INTS2 subunit 2

Chromosome 9 open reading 6563 0,0388874 0,3239269 25 15,3 1,634 C9orf52 frame 52 exocyst complex 465 0,0005136 0,0602236 77,4 47,4 1,633 EXOC2 component 2 sel-1 suppressor of lin-12-like (C. 936 0,0014136 0,082425 69,9 42,8 1,633 SEL1L elegans) UPF3 regulator of nonsense transcripts homolog A 1668 0,0035807 0,117371 440,8 270 1,633 UPF3A (yeast) solute carrier family 25, 1961 0,0046946 0,1308328 152,2 93,2 1,633 SLC25A35 member 35 Ras association (RalGDS/AF-6) domain family 4300 0,0186346 0,2368636 16 9,8 1,633 RASSF3 3 zinc finger, 7039 0,0442379 0,3436152 120,7 73,9 1,633 ZMYM3 MYM-type 3 integrin alpha FG-GAP repeat containing 1 /// integrin alpha FG-GAP repeat 379 0,0004039 0,0577756 586,9 359,7 1,632 ITFG1 containing 1

angel homolog 2281 0,0061901 0,1483752 88,6 54,3 1,632 ANGEL1 1 (Drosophila) solute carrier family 35, 2365 0,0066022 0,1526323 49,6 30,4 1,632 SLC35B4 member B4 dihydrolipoami de branched chain transacylase 2395 0,0067377 0,1538137 18,6 11,4 1,632 DBT E2 mitochondrial methionyl- tRNA formyltransfera 2972 0,0098283 0,1808083 47,5 29,1 1,632 MTFMT se

AP1 gamma subunit binding 6249 0,03597 0,3147159 83,4 51,1 1,632 AP1GBP1 protein 1

TROVE domain family, 6355 0,0369861 0,3182035 113,1 69,3 1,632 TROVE2 member 2 spermatid perinuclear RNA binding 1831 0,0041673 0,1243707 23 14,1 1,631 STRBP protein structural maintenance of chromosomes 2111 0,0053785 0,1392802 518,7 318,1 1,631 SMC1A 1A ring finger 4626 0,0212352 0,2509802 88,9 54,5 1,631 RNF14 protein 14 CDNA clone IMAGE:526121 7433 0,0484546 0,3563889 311,2 190,8 1,631 NA 3 elongation protein 3 homolog (S. 889 0,0012919 0,079454 128,8 79 1,63 ELP3 cerevisiae) transmembran e emp24-like trafficking protein 10 1731 0,0037978 0,1199565 1210 742,2 1,63 TMED10 (yeast)

coproporphyrin 2222 0,0058601 0,1441488 182,9 112,2 1,63 CPOX ogen oxidase ribonuclease 3303 0,0118508 0,1961679 178,2 109,3 1,63 RNASEN III, nuclear zinc finger, 3661 0,0138065 0,2061924 145,6 89,3 1,63 ZMAT3 matrin type 3 origin recognition complex, subunit 2-like 3992 0,0162676 0,2228034 37,5 23 1,63 ORC2L (yeast) anaphase promoting complex 615 0,00074 0,0657513 145,8 89,5 1,629 ANAPC1 subunit 1

UDP-N-acetyl- alpha-D- galactosamine: polypeptide N- acetylgalactos aminyltransfer ase 1 (GalNAc- 957 0,0014693 0,0839343 1163,3 714,2 1,629 GALNT1 T1) HIG1 domain family, member 2786 0,0088573 0,1738237 1499,3 920,1 1,629 HIGD1A 1A signal peptide peptidase-like 2837 0,009106 0,1754434 1165,6 715,6 1,629 SPPL2A 2A

phosphatidylin ositol transfer protein, 6240 0,0358975 0,3144925 11,4 7 1,629 PITPNC1 cytoplasmic 1 proline-rich transmembran 6933 0,043044 0,3394534 37,3 22,9 1,629 PRRT3 e protein 3 exostoses 496 0,0005664 0,0624087 255 156,6 1,628 EXT2 (multiple) 2

ARV1 homolog 4119 0,0172453 0,2288456 309,9 190,4 1,628 ARV1 (S. cerevisiae) TIA1 cytotoxic granule- associated RNA binding 5509 0,0288374 0,2861008 172,9 106,2 1,628 TIA1 protein aminoadipate- semialdehyde dehydrogenas e- phosphopantet heinyl 6773 0,0414724 0,334719 304,2 186,9 1,628 AASDHPPT transferase hypothetical 7229 0,0462841 0,3500599 28 17,2 1,628 LOC554203 LOC554203 zinc finger with KRAB and SCAN 7517 0,0493852 0,3592039 109,4 67,2 1,628 ZKSCAN1 domains 1 Transcribed 1102 0,001857 0,0921338 130,2 80 1,627 NA locus

RAB, member of RAS oncogene family-like 3 /// similar to RAB, member of RABL3 /// RAS oncogene 1211 0,0021646 0,0976662 68 41,8 1,627 LOC653256 family-like 3 keratin associated 1773 0,003965 0,1221979 211,3 129,9 1,627 KRTAP4-7 protein 4-7 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyt 2373 0,0066327 0,1528204 129,8 79,8 1,627 PTPN4 e) LMBR1 domain 2789 0,0088771 0,1740249 10,9 6,7 1,627 LMBRD2 containing 2 KIAA0746 3628 0,0136239 0,2052986 204,5 125,7 1,627 KIAA0746 protein solute carrier family 33 (acetyl-CoA transporter), 3683 0,013946 0,2070316 128,4 78,9 1,627 SLC33A1 member 1

thiamine 1015 0,001609 0,0866252 84,4 51,9 1,626 THTPA triphosphatase

chromosome 7 open reading 2435 0,0069427 0,1557913 1270 780,9 1,626 C7orf24 frame 24 zinc binding alcohol dehydrogenas e, domain 4703 0,0218529 0,2540098 26,5 16,3 1,626 ZADH2 containing 2 ATPase, H+ transporting, lysosomal 42kDa, V1 5480 0,0285138 0,2844297 211 129,8 1,626 ATP6V1C1 subunit C1 fumarate 861 0,0012494 0,0791194 576,7 354,9 1,625 FH hydratase CD22 molecule /// myelin CD22 /// associated 950 0,0014406 0,0829103 56,4 34,7 1,625 MAG glycoprotein protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A 1372 0,0026386 0,1048471 46 28,3 1,625 PPP3CB beta)

uridine monophosphat e synthetase (orotate phosphoribosyl transferase and orotidine- 5@#$%&- 2265 0,0060949 0,1470941 120,1 73,9 1,625 UMPS decarboxylase) BRCA1/BRCA 2-containing complex, 2471 0,0071221 0,1575884 451,5 277,9 1,625 BRCC3 subunit 3 GLE1 RNA export mediator-like 2682 0,0083092 0,1693886 192,9 118,7 1,625 GLE1L (yeast) coenzyme Q9 homolog (S. 2763 0,0087551 0,1732311 277,1 170,5 1,625 COQ9 cerevisiae) zinc finger protein 19 /// zinc finger ZNF19 /// protein 23 2842 0,0091321 0,1756254 41,1 25,3 1,625 ZNF23 (KOX 16) 3853 0,0152752 0,2167579 14,3 8,8 1,625 MCOLN2 mucolipin 2 nuclear receptor subfamily 2, group C, 5140 0,0255332 0,2716007 84 51,7 1,625 NR2C1 member 1 glucocorticoid induced 5542 0,029079 0,286881 20,8 12,8 1,625 GLCCI1 transcript 1

coiled-coil domain 446 0,0004807 0,0589289 54,9 33,8 1,624 CCDC128 containing 128 engulfment and cell motility 932 0,0014061 0,082425 205,8 126,7 1,624 ELMO2 2 ubiquitination factor E4B (UFD2 homolog, 1466 0,0029345 0,1093314 54,4 33,5 1,624 UBE4B yeast) SLIT-ROBO Rho GTPase activating 2324 0,0063799 0,1498086 54,9 33,8 1,624 SRGAP2 protein 2 immunoglobuli n heavy locus /// immunoglobuli n heavy constant gamma 1 (G1m marker) /// IGH@ /// immunoglobuli IGHG1 /// n heavy 5601 0,0295863 0,2887713 22,9 14,1 1,624 IGHM constant mu

leukocyte immunoglobuli n-like receptor, subfamily A (with TM domain), 7394 0,0480479 0,355236 29,4 18,1 1,624 LILRA5 member 5

adaptor-related protein complex 3, mu 639 0,0007835 0,0670389 376,3 231,9 1,623 AP3M1 1 subunit ankyrin repeat 1632 0,0034736 0,1161645 33,1 20,4 1,623 ANKRD16 domain 16 4022 0,0165365 0,2247969 130,3 80,3 1,623 11-sept Septin 11

SMAD family member 3 /// uroporphyrinog SMAD3 /// en 4155 0,0175063 0,2303627 342,9 211,3 1,623 UROD decarboxylase

uridine-cytidine 4769 0,0223773 0,2565483 151,9 93,6 1,623 UCK2 kinase 2 asparaginyl- tRNA synthetase 2 (mitochondrial) 5158 0,0256953 0,2723069 115,3 71,1 1,622 NARS2 (putative) chromosome 11 open reading frame 567 0,000666 0,064104 194,3 119,9 1,621 C11orf17 17 ash2 (absent, small, or homeotic)-like 1271 0,0023174 0,0996883 424,6 262 1,621 ASH2L (Drosophila) UEV and lactate/malate dehyrogenase 1599 0,0033844 0,1157236 103,6 63,9 1,621 UEVLD domains sorting nexin 1765 0,0039205 0,1214467 225,5 139,1 1,621 SNX13 13 dCMP 2022 0,0050045 0,135322 186,4 115 1,621 DCTD deaminase integrator complex 2274 0,00616 0,1481082 129,7 80 1,621 INTS4 subunit 4 solute carrier family 44, 3435 0,0125583 0,1997647 56,4 34,8 1,621 SLC44A2 member 2

egf-like module containing, mucin-like, hormone 6713 0,0406831 0,3313494 222,4 137,2 1,621 EMR2 receptor-like 2

562 0,0006605 0,064104 401,8 248,1 1,62 SNX1 sorting nexin 1 mitochondrial tumor 638 0,000782 0,0670154 26,4 16,3 1,62 MTUS1 suppressor 1 RAB14, member RAS oncogene 1010 0,0016009 0,0866252 17,5 10,8 1,62 RAB14 family ATG7 autophagy related 7 homolog (S. 1113 0,0018921 0,0929475 85,4 52,7 1,62 ATG7 cerevisiae) protein arginine methyltransfer 1792 0,0040384 0,1231132 83,6 51,6 1,62 PRMT3 ase 3 2661 0,0082119 0,1687282 34,5 21,3 1,62 KIAA0586 KIAA0586 kelch-like 20 7456 0,0486804 0,3569744 51,2 31,6 1,62 KLHL20 (Drosophila) malic enzyme 2, NAD(+)- dependent, mitochondrial /// protein kinase, cAMP- dependent, ME2 /// regulatory, 813 0,0011361 0,0763636 529,9 327,2 1,619 PRKAR2B type II, beta SMAD family 3902 0,0156049 0,2186258 111,7 69 1,619 SMAD2 member 2

phosphoribosyl formylglycinam idine synthase (FGAR amidotransfera 1463 0,0029304 0,1093314 121 74,8 1,618 PFAS se) Transcribed 1554 0,0032373 0,1138946 8,9 5,5 1,618 NA locus

RFT1 homolog 1824 0,0041519 0,1242557 117 72,3 1,618 RFT1 (S. cerevisiae)

TMEM9 domain family, 4076 0,0169492 0,2273546 371,6 229,7 1,618 TMEM9B member B 4171 0,0176525 0,2313955 57,6 35,6 1,618 KIAA1026 kazrin CGG triplet repeat binding 152 0,0001262 0,0449393 215,7 133,4 1,617 CGGBP1 protein 1 nuclear receptor co- repressor 1 /// chromosome 20 open NCOR1 /// reading frame 716 0,0009311 0,0708877 65,8 40,7 1,617 C20orf191 191 N- acylsphingosin e amidohydrolas e (acid 780 0,0010755 0,0753005 2242,6 1386,8 1,617 ASAH1 ceramidase) 1 secretory carrier membrane 994 0,0015578 0,0856868 83,3 51,5 1,617 SCAMP1 protein 1 pentatricopepti de repeat 3208 0,0113338 0,1931276 31,7 19,6 1,617 PTCD2 domain 2 microtubule- actin crosslinking 4423 0,0196493 0,2428313 287,5 177,8 1,617 MACF1 factor 1 zinc finger DAZ interacting 564 0,0006629 0,064104 11,8 7,3 1,616 DZIP3 protein 3

chromosome X open reading 1515 0,0030798 0,1111472 50,1 31 1,616 CXorf12 frame 12

growth arrest- 1619 0,0034376 0,1160907 416,8 258 1,616 GAS2L3 specific 2 like 3 dipeptidyl- 2852 0,0091831 0,176047 248,1 153,5 1,616 DPP3 peptidase 3 Chromosome 21 open reading frame 2880 0,0093051 0,1765671 20,2 12,5 1,616 C21orf86 86 X-prolyl aminopeptidas e (aminopeptida se P) 1, 3333 0,0119928 0,1967316 245,2 151,7 1,616 XPNPEP1 soluble glucosidase, beta; acid (includes glucosylcerami dase) /// glucosidase, GBA /// beta; acid, 4021 0,0165295 0,2247576 509,2 315,1 1,616 GBAP pseudogene 4762 0,0223089 0,2560628 887,9 549,3 1,616 TNS3 tensin 3 Homeodomain interacting protein kinase 5470 0,0284337 0,284207 875,8 542 1,616 HIPK2 2 SET translocation (myeloid leukemia- 355 0,000363 0,0556372 1204,2 745,5 1,615 SET associated)

solute carrier family 39 (zinc transporter), 540 0,0006311 0,0635709 104,5 64,7 1,615 SLC39A6 member 6 phosphatidylch oline transfer 1141 0,0019763 0,0946254 239,8 148,5 1,615 PCTP protein acidic repeat 1184 0,002085 0,0961653 12,6 7,8 1,615 ACRC containing

signal transducing adaptor molecule (SH3 domain and 2705 0,008404 0,1698255 180,6 111,8 1,615 STAM2 ITAM motif) 2 tumor suppressor 3088 0,010583 0,187372 167,6 103,8 1,615 TUSC1 candidate 1

chromosome 1 open reading 3852 0,0152687 0,2167228 173,6 107,5 1,615 C1orf19 frame 19

NADH dehydrogenas e (ubiquinone) 1 beta subcomplex, 9, 4476 0,0200088 0,2444104 2095,1 1297,3 1,615 NDUFB9 22kDa FYN binding protein (FYB- 5777 0,0311183 0,2945115 352,5 218,2 1,615 FYB 120/130) potassium channel tetramerisation domain 5910 0,032408 0,2997838 36,5 22,6 1,615 KCTD15 containing 15 hypothetical protein 6801 0,0417442 0,3355924 60,4 37,4 1,615 P15RS FLJ10656 glutathione transferase zeta 1 (maleylacetoac etate 1452 0,0028691 0,1080358 109,3 67,7 1,614 GSTZ1 isomerase) dipeptidyl- 3913 0,0156617 0,2187531 165,9 102,8 1,614 DPP3 peptidase 3

transmembran 6631 0,0396513 0,3268909 169,1 104,8 1,614 TMEM168 e protein 168

major facilitator superfamily domain 1154 0,0020091 0,0950722 3199,4 1983 1,613 MFSD1 containing 1 Peroxiredoxin 1393 0,0026799 0,1051856 12,1 7,5 1,613 PRDX6 6 collagen, type 4790 0,0225613 0,2575238 47,1 29,2 1,613 COL6A1 VI, alpha 1 inositol monophosphat ase domain 5114 0,0252434 0,2698832 135,3 83,9 1,613 IMPAD1 containing 1 acyl-CoA synthetase short-chain family member 5365 0,0274495 0,2797393 183,9 114 1,613 ACSS2 2 chloride channel 5 (nephrolithiasis 2, X-linked, 6418 0,0375082 0,3195327 106 65,7 1,613 CLCN5 Dent disease) serine/threonin 783 0,0010833 0,0755211 909,3 564 1,612 STK38 e kinase 38 KIAA1219 /// 1457 0,0028927 0,1085507 113,5 70,4 1,612 KIAA1219 KIAA1219 2785 0,0088506 0,1737546 15,8 9,8 1,612 NA NA Sp2 transcription 4690 0,0217677 0,2537207 22,4 13,9 1,612 SP2 factor phospholipase A2, group VII (platelet- activating factor acetylhydrolas e, plasma) /// phospholipase A2, group VII (platelet- activating factor acetylhydrolas 5218 0,0262486 0,2749963 2143,5 1329,5 1,612 PLA2G7 e, plasma) germ cell-less homolog 1 5793 0,0312558 0,2949742 40,3 25 1,612 GMCL1 (Drosophila) chromosome 11 open reading frame 444 0,0004773 0,0587756 186,6 115,8 1,611 C11orf54 54 exocyst complex 643 0,0007948 0,0675827 88,3 54,8 1,611 EXOC5 component 5 NIF3 NGG1 interacting factor 3-like 1 1677 0,0036168 0,1177064 191,1 118,6 1,611 NIF3L1 (S. pombe) 2905 0,0094056 0,1770228 89,4 55,5 1,611 KIAA0859 KIAA0859 solute carrier family 5 (sodium- dependent vitamin transporter), 1212 0,002165 0,0976662 141,2 87,7 1,61 SLC5A6 member 6 transmembran e emp24-like trafficking protein 10 1380 0,0026501 0,1048471 1582,3 982,5 1,61 TMED10 (yeast) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, 1398 0,0027 0,1055955 148 91,9 1,61 SMARCA2 member 2 1736 0,0038108 0,1200204 740,3 459,7 1,61 CANX calnexin nuclear transcription factor, X-box 2409 0,0068395 0,1552112 31,4 19,5 1,61 NFX1 binding 1

Leucine zipper transcription 4010 0,0164602 0,2244293 29,3 18,2 1,61 LZTR2 regulator 2 UDP-glucose ceramide glucosyltransfe 955 0,0014552 0,0833121 88 54,7 1,609 UGCGL1 rase-like 1 src kinase associated phosphoprotei 1473 0,0029529 0,109553 281,1 174,7 1,609 SKAP2 n 2 hypothetical protein 2333 0,0063982 0,149945 17,7 11 1,609 MGC23284 MGC23284 muscle RAS oncogene 6986 0,043699 0,341888 112,3 69,8 1,609 MRAS homolog

triggering receptor expressed on 472 0,0005199 0,0602236 3477,8 2163 1,608 TREM2 myeloid cells 2 Chromosome 10 open reading frame 3440 0,0125708 0,1997647 105,8 65,8 1,608 C10orf18 18 4265 0,0183143 0,2347794 32,8 20,4 1,608 KIAA0146 KIAA0146 insulin- degrading 1193 0,0021173 0,0969771 122,8 76,4 1,607 IDE enzyme chromosome 20 open reading frame 1281 0,0023647 0,1008909 205,4 127,8 1,607 C20orf44 44 2371 0,0066308 0,1528204 212,1 132 1,607 KIAA0859 KIAA0859 3089 0,0105918 0,187372 13,5 8,4 1,607 GCRG224 GCRG-P224

chromosome 6 open reading 3668 0,0138741 0,2068065 1691,1 1052,2 1,607 C6orf51 frame 51 phosphoglucon ate dehydrogenas e /// phosphoglucon ate dehydrogenas e /// UDP- glucose dehydrogenas e /// UDP- glucose PGD /// dehydrogenas 4259 0,0182753 0,2345596 2910,6 1810,7 1,607 UGDH e Kelch-like 8 5096 0,0251137 0,269445 9,8 6,1 1,607 KLHL8 (Drosophila) chromosome 20 open reading frame 5801 0,0313174 0,2950284 23,3 14,5 1,607 C20orf44 44 zinc finger, CDGSH-type 507 0,0005827 0,0628117 102,8 64 1,606 ZCD1 domain 1 RAN binding 1246 0,0022502 0,0986109 177,5 110,5 1,606 RANBP5 protein 5 chloride channel 5 (nephrolithiasis 2, X-linked, 1691 0,0036419 0,1177064 10,6 6,6 1,606 CLCN5 Dent disease) chromodomain helicase DNA binding protein 2597 0,0079173 0,1666005 22,8 14,2 1,606 CHD6 6 transmembran e emp24 protein transport domain 5228 0,0263117 0,2751348 346,4 215,7 1,606 TMED3 containing 3 diacylglycerol kinase, theta 6117 0,0345569 0,3088767 172,2 107,2 1,606 DGKQ 110kDa

transducin (beta)-like 1X- linked receptor 1 /// transducin (beta)-like 1X- linked receptor 6646 0,0398601 0,3278387 103,1 64,2 1,606 TBL1XR1 1 lysophospholip 1390 0,0026775 0,1051826 918,3 572,3 1,605 LYPLA1 ase I ADP- ribosylation 6427 0,0376117 0,3199657 231,8 144,5 1,604 ARL11 factor-like 11 zinc finger 759 0,0010215 0,0735843 58,5 36,5 1,603 ZNF434 protein 434 transmembran 1024 0,0016403 0,0875814 102,4 63,9 1,603 TMEM64 e protein 64

selenophospha 1118 0,0019173 0,0937195 127,9 79,8 1,603 SEPHS1 te synthetase 1 hypothetical protein 4792 0,0226034 0,2578256 94,1 58,7 1,603 HSPC268 HSPC268

Rabaptin, RAB GTPase binding effector 4999 0,0242816 0,2655318 48,9 30,5 1,603 RABEP1 protein 1 Impact homolog 5639 0,029872 0,2896234 80 49,9 1,603 IMPACT (mouse) dexamethason e-induced 6116 0,0345508 0,3088726 55,8 34,8 1,603 DEXI transcript hypothetical 6410 0,0374053 0,3190538 35,9 22,4 1,603 LOC441440 LOC441440

oculocerebrore nal syndrome 378 0,0004024 0,0577756 63,1 39,4 1,602 OCRL of Lowe

selenophospha 917 0,0013587 0,0810108 112,3 70,1 1,602 SEPHS1 te synthetase 1 transmembran e and coiled- coil domain 2195 0,0057518 0,1432709 96,6 60,3 1,602 TMCC1 family 1 arginine- glutamic acid dipeptide (RE) 6082 0,0341623 0,3071068 15,7 9,8 1,602 RERE repeats opsin 3 (encephalopsin 1060 0,0017301 0,0891702 1027,7 642 1,601 OPN3 , panopsin) chromosome 20 open reading frame 1314 0,0024818 0,1029968 86,6 54,1 1,601 C20orf142 142

zinc finger, MYND domain 2575 0,0077815 0,1652247 554,1 346 1,601 ZMYND11 containing 11 SPFH domain family, member 3037 0,0102363 0,1842303 371 231,8 1,601 SPFH1 1 discoidin, CUB and LCCL domain 3390 0,0123192 0,1984223 32,5 20,3 1,601 DCBLD1 containing 1 5,10- methenyltetrah ydrofolate synthetase (5- formyltetrahydr ofolate cyclo- 4447 0,0198158 0,2436314 91,9 57,4 1,601 MTHFS ligase) Leo1, Paf1/RNA polymerase II complex component, homolog (S. 2620 0,0080205 0,1673744 67,7 42,3 1,6 LEO1 cerevisiae) ATPase, H+ transporting, lysosomal 42kDa, V1 3648 0,0137046 0,2053999 341,4 213,4 1,6 ATP6V1C1 subunit C1

succinate dehydrogenas e complex, subunit C, integral membrane protein, 15kDa /// similar to succinate dehydrogenas e complex, subunit C SDHC /// isoform 3 3965 0,0160518 0,2213448 244,7 152,9 1,6 LOC642502 precursor Zinc finger 6121 0,0346682 0,309669 19,2 12 1,6 ZNF320 protein 320 888 0,0012916 0,079454 63,5 39,7 1,599 KIAA0350 KIAA0350

vacuolar protein sorting 41 homolog (S. 1114 0,0019023 0,0933647 106,2 66,4 1,599 VPS41 cerevisiae) Thioredoxin- 2930 0,0096101 0,1793284 45,9 28,7 1,599 TXNL5 like 5

trafficking protein particle 3255 0,01154 0,1936505 555,5 347,4 1,599 TRAPPC2L complex 2-like multiple endocrine 3804 0,0148298 0,2130946 115,9 72,5 1,599 MEN1 neoplasia I

1-acylglycerol- 3-phosphate O- acyltransferase 4721 0,0219683 0,2543893 91 56,9 1,599 AGPAT3 3

6948 0,0432817 0,3405911 334,5 209,2 1,599 PARVG parvin, gamma solute carrier family 39 (metal ion transporter), 7058 0,0444446 0,3442 308,2 192,8 1,599 SLC39A11 member 11 polyribonucleot ide nucleotidyltran 2690 0,0083483 0,1695229 204,9 128,2 1,598 PNPT1 sferase 1 ubiquitin specific 4100 0,0171222 0,2282885 59,6 37,3 1,598 USP54 peptidase 54

5714 0,0305967 0,2927394 13,1 8,2 1,598 ALPK1 alpha-kinase 1 7187 0,0458072 0,3484776 38,5 24,1 1,598 NA NA death- associated protein kinase 978 0,0015156 0,0846932 752 471 1,597 DAPK1 1

prolyl 1751 0,0038844 0,1210936 216,1 135,3 1,597 PREP endopeptidase peroxisomal biogenesis 1985 0,0048182 0,1326598 82,7 51,8 1,597 PEX3 factor 3

6504 0,038341 0,322196 763,8 478,4 1,597 SNX5 sorting nexin 5 dyslexia susceptibility 1 761 0,0010328 0,0742028 9,1 5,7 1,596 DYX1C1 candidate 1 chromosome 19 open reading frame 1996 0,0048638 0,1332306 560 350,8 1,596 C19orf28 28 aarF domain containing 2131 0,0054702 0,1403487 57,6 36,1 1,596 ADCK1 kinase 1 tripartite motif- containing 34 /// tripartite motif- containing 6 TRIM34 /// and tripartite TRIM6- motif- 2271 0,0061488 0,1480342 34 21,3 1,596 TRIM34 containing 34 peroxisomal biogenesis 4630 0,0212565 0,2510149 22,5 14,1 1,596 PEX14 factor 14 Transcribed 6947 0,0432776 0,3405911 68 42,6 1,596 NA locus 1284 0,0023741 0,1010934 340,2 213,3 1,595 CCNK Cyclin K

COX15 homolog, cytochrome c oxidase assembly 3883 0,0154697 0,2178228 304,2 190,7 1,595 COX15 protein (yeast) Acyl-CoA synthetase short-chain family member 4228 0,0180591 0,2334877 23,6 14,8 1,595 ACSS2 2 pyruvate 757 0,0010197 0,0735843 193 121,1 1,594 PC carboxylase mitochondrial ribosomal 766 0,0010511 0,0750247 439,6 275,7 1,594 MRPS35 protein S35 glutamic- oxaloacetic transaminase 2, mitochondrial (aspartate aminotransfera 2256 0,0060553 0,1467504 539,3 338,3 1,594 GOT2 se 2) CDNA clone IMAGE:531417 8 /// CDNA clone IMAGE:53141 2779 0,00881 0,1732843 139 87,2 1,594 NA 78 mannosidase, alpha, class 3152 0,0109582 0,1900824 51 32 1,594 MAN1A2 1A, member 2 adenylate 3305 0,0118633 0,196206 82,9 52 1,594 ADCY4 cyclase 4

Full-length cDNA clone CS0DB009YL2 0 of Neuroblastoma Cot 10- normalized of Homo sapiens 3590 0,0134272 0,2043749 48,3 30,3 1,594 NA (human) gamma- glutamyl 4170 0,017637 0,2312477 129,3 81,1 1,594 GGCX carboxylase

TBC1 (tre- 2/USP6, BUB2, cdc16) domain family, 4231 0,0180792 0,2335758 113,3 71,1 1,594 TBC1D1 member 1 intestinal cell (MAK-like) 5457 0,0282935 0,2834256 11 6,9 1,594 ICK kinase limb region 1 homolog (mouse) /// limb region 1 homolog 5992 0,0332672 0,3035521 45,1 28,3 1,594 LMBR1 (mouse) exostoses 1033 0,0016651 0,0879972 152,3 95,6 1,593 EXT2 (multiple) 2

CDNA FLJ43345 fis, clone 4187 0,0177474 0,2317274 17,2 10,8 1,593 NA NT2RI3008228 protein tyrosine phosphatase, non-receptor type 18 (brain- 5293 0,0268248 0,2770916 9,4 5,9 1,593 PTPN18 derived) solute carrier family 25, 6383 0,0371548 0,3182155 191,6 120,3 1,593 SLC25A43 member 43 insulin- degrading 399 0,0004257 0,0577884 126,6 79,5 1,592 IDE enzyme eukaryotic translation initiation factor 486 0,0005479 0,0615795 82,6 51,9 1,592 EIF5B 5B fucosidase, alpha-L- 2, 880 0,0012748 0,0792042 489,1 307,3 1,592 FUCA2 plasma dihydrolipoami de dehydrogenas 1418 0,0027689 0,1067259 903,6 567,5 1,592 DLD e splicing factor, arginine/serine- 1454 0,0028777 0,1081851 102,2 64,2 1,592 SFRS2B rich 2B zinc finger 3196 0,0112785 0,1929325 397,4 249,6 1,592 ZNF664 protein 664 jerky homolog- 7285 0,0469719 0,3525296 77 48,4 1,591 JRKL like (mouse)

tyrosine 3- monooxygenas e/tryptophan 5- monooxygenas e activation protein, beta 285 0,0002744 0,0525339 1616,6 1016,5 1,59 YWHAB polypeptide src kinase associated phosphoprotei 392 0,0004159 0,0577756 889,5 559,3 1,59 SKAP2 n 2 phosphatidylin ositol 4-kinase 2528 0,0074674 0,1615032 185,9 116,9 1,59 PI4KII type II zinc finger, DHHC-type 3379 0,0122663 0,1984192 216,4 136,1 1,59 ZDHHC16 containing 16 Ras and Rab 3750 0,0143375 0,2090407 666,1 418,8 1,59 RIN2 interactor 2 nucleoporin 7550 0,0497438 0,3600842 158,8 99,9 1,59 NUP133 133kDa splicing factor, arginine/serine- rich 2, interacting 614 0,0007399 0,0657513 791,1 497,9 1,589 SFRS2IP protein CDNA FLJ34482 fis, clone HLUNG20040 1662 0,0035651 0,1172588 307,7 193,6 1,589 NA 67

Signal sequence receptor, alpha (translocon- associated 3841 0,0151592 0,2157848 216,1 136 1,589 SSR1 protein alpha) inositol 1,4,5- trisphosphate 4070 0,0168834 0,2268059 17 10,7 1,589 ITPKB 3-kinase B 6959 0,0434285 0,3412061 133,6 84,1 1,589 IPO13 importin 13 cell cycle 7042 0,0442824 0,3437114 73,4 46,2 1,589 CCPG1 progression 1 melanoma inhibitory activity family, 786 0,0010884 0,0756026 197,4 124,3 1,588 MIA3 member 3 transmembran 1874 0,0043817 0,1278386 317,2 199,8 1,588 TMEM181 e protein 181 myeloid differentiation primary response gene 3955 0,0159794 0,2208555 1643,2 1034,5 1,588 MYD88 (88) 5380 0,0275824 0,2802874 159,6 100,5 1,588 NA NA

acireductone 6607 0,0393567 0,3256522 503,8 317,2 1,588 ADI1 dioxygenase 1

solute carrier family 30 (zinc transporter), 940 0,0014183 0,082425 255,9 161,2 1,587 SLC30A9 member 9

malonyl-CoA 1807 0,0040925 0,123808 138,4 87,2 1,587 MLYCD decarboxylase chromosome 15 open reading frame 6662 0,0400965 0,3290236 130,8 82,4 1,587 C15orf40 40 proprotein convertase subtilisin/kexin 6693 0,0404647 0,3305554 130 81,9 1,587 PCSK5 type 5 Transcribed 1107 0,0018743 0,0925721 485,3 305,9 1,586 NA locus TBC1 domain family, member 1835 0,0041928 0,1249272 75,8 47,8 1,586 TBC1D24 24 kelch-like 9 4018 0,0165098 0,2246574 313,4 197,6 1,586 KLHL9 (Drosophila) protein tyrosine phosphatase, non-receptor type 11 (Noonan 975 0,0015027 0,0842668 103,8 65,5 1,585 PTPN11 syndrome 1) chromosome 20 open reading frame 991 0,0015553 0,0856868 309,5 195,3 1,585 C20orf30 30

NADH dehydrogenas e (ubiquinone) Fe-S protein 1, 75kDa (NADH- coenzyme Q 1244 0,0022433 0,0985952 407,9 257,4 1,585 NDUFS1 reductase) transmembran 2756 0,0087094 0,1727429 263,1 166 1,585 TMEM77 e protein 77 mitochondrial ribosomal 2800 0,0089689 0,1750515 219,2 138,3 1,585 MRPS25 protein S25 NFU1 iron- sulfur cluster scaffold homolog (S. 2332 0,006395 0,1499342 240,9 152,1 1,584 NFU1 cerevisiae) Transcribed 4074 0,0169202 0,2270771 746,1 471,1 1,584 NA locus 4- aminobutyrate aminotransfera 6014 0,0335004 0,3045583 177,7 112,2 1,584 ABAT se ubiquitin carboxyl- terminal 560 0,0006581 0,064104 36,1 22,8 1,583 UCHL5 hydrolase L5 phenylalanine- tRNA synthetase- like, beta 1268 0,0023018 0,0992515 9,5 6 1,583 FARSLB subunit mitochondrial ribosomal 2396 0,0067478 0,15398 372,4 235,2 1,583 MRPL37 protein L37

T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 2462 0,0070895 0,1572947 1102,8 696,6 1,583 TCIRG1 subunit A3 CDK2- associated 4631 0,021277 0,2511556 152,9 96,6 1,583 CDK2AP2 protein 2 tetraspanin 14 /// tetraspanin 4980 0,0241263 0,2648362 257,7 162,8 1,583 TSPAN14 14

chromosome 4 open reading 2772 0,0087934 0,1732398 39,4 24,9 1,582 C4orf28 frame 28 3101 0,0106394 0,1874018 185,9 117,5 1,582 NA NA hypothetical protein 4370 0,0191995 0,2402134 228,4 144,4 1,582 FLJ31033 FLJ31033 heat shock 70kDa protein 4924 0,0236186 0,2622557 454,4 287,2 1,582 HSPA4 4 TSR1, 20S rRNA accumulation, homolog (S. 5349 0,0273469 0,2794089 98,1 62 1,582 TSR1 cerevisiae) proteasome maturation 7006 0,0438511 0,3422071 121,2 76,6 1,582 POMP protein endonuclease 265 0,0002532 0,0521767 40,8 25,8 1,581 ENDOGL1 G-like 1

transmembran e 9 superfamily 908 0,0013384 0,0805914 1736,5 1098,7 1,581 TM9SF2 member 2 4430 0,0196893 0,2430051 249,3 157,7 1,581 CCNG2 cyclin G2 5869 0,0319335 0,2974892 246,3 155,8 1,581 MCOLN1 mucolipin 1 Rho-related BTB domain 669 0,0008536 0,0697147 43,3 27,4 1,58 RHOBTB2 containing 2 CDNA FLJ31919 fis, clone NT2RP700496 1255 0,0022644 0,0986109 246,2 155,8 1,58 NA 4 farnesyl- diphosphate farnesyltransfe 4496 0,0202233 0,2459038 557,5 352,8 1,58 FDFT1 rase 1

Homo sapiens, clone IMAGE:46956 4700 0,0218329 0,2539817 115,8 73,3 1,58 NA 48, mRNA phosphodieste 7194 0,0459011 0,3488522 202,7 128,3 1,58 PDE8A rase 8A general transcription factor IIIC, polypeptide 2, 410 0,0004361 0,0577884 517,2 327,6 1,579 GTF3C2 beta 110kDa hypothetical protein 1238 0,0022209 0,0980838 67,6 42,8 1,579 MGC33302 MGC33302

multiple EGF- 1977 0,004776 0,1320829 324 205,2 1,579 MEGF9 like-domains 9

hypothetical protein LOC729083 /// LOC729083 hypothetical /// protein 2150 0,0055551 0,1412675 9 5,7 1,579 LOC731604 LOC731604 chaperonin containing TCP1, subunit 2163 0,0056048 0,1416747 32,2 20,4 1,578 CCT6B 6B (zeta 2) Interleukin 10 2615 0,0080066 0,1673744 112,5 71,3 1,578 IL10RB receptor, beta tubulin folding 3295 0,0117621 0,1951534 62 39,3 1,578 TBCD cofactor D Dedicator of 4639 0,0213223 0,2513035 336,1 213 1,578 DOCK5 cytokinesis 5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), 2935 0,0096422 0,1796209 4151,5 2632,6 1,577 SLC25A5 member 5 two pore segment 3455 0,0126383 0,1999997 96,2 61 1,577 TPCN2 channel 2 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, 4438 0,019756 0,2433561 582,4 369,2 1,577 ITGB1 MSK12) tubulin folding 4680 0,0216884 0,253301 44,3 28,1 1,577 TBCE cofactor E zinc finger 5474 0,0284548 0,2842101 88,3 56 1,577 ZNF18 protein 18 mitogen- activated protein kinase kinase kinase 5502 0,0287535 0,285732 25,7 16,3 1,577 MAP4K4 kinase 4 myelin protein 2557 0,0076356 0,1631875 26,8 17 1,576 MPZL1 zero-like 1 chromosome 18 open reading frame 2657 0,008186 0,1684492 310,8 197,2 1,576 C18orf55 55

nudix (nucleoside diphosphate linked moiety X)-type motif 4 /// nudix (nucleoside diphosphate linked moiety NUDT4 /// X)-type motif 4 3300 0,0117984 0,195478 14,5 9,2 1,576 NUDT4P1 pseudogene 1 4332 0,0188368 0,2377429 9,3 5,9 1,576 NA NA 6225 0,0357175 0,3137115 71,4 45,3 1,576 NA ELISC-1 hypothetical protein 5729 0,0307971 0,2937838 53,7 34,1 1,575 FLJ35779 FLJ35779

methylthioaden osine 436 0,0004666 0,0583909 15,9 10,1 1,574 MTAP phosphorylase serum/glucoco rticoid regulated kinase family, 2246 0,0060112 0,1463323 461,4 293,1 1,574 SGK3 member 3 epoxide hydrolase 1, microsomal 2964 0,0097863 0,1805216 211,9 134,6 1,574 EPHX1 (xenobiotic) leucyl-tRNA 4468 0,0199547 0,244186 445,4 282,9 1,574 LARS synthetase

F-box and WD- 40 domain 6823 0,0419176 0,3358999 9,6 6,1 1,574 FBXW2 protein 2

chromosome 7 open reading 1020 0,0016296 0,0873514 24,7 15,7 1,573 C7orf46 frame 46 Ras-related 1388 0,0026745 0,1051826 1956,7 1243,9 1,573 RRAGD GTP binding D Sperm associated 4104 0,0171573 0,2285213 47,5 30,2 1,573 SPAG6 antigen 6 Fanconi anemia, complementati on group A /// Fanconi anemia, complementati 7317 0,0472779 0,3532612 37,6 23,9 1,573 FANCA on group A armadillo repeat 7404 0,048137 0,3554687 295,3 187,9 1,572 ARMC1 containing 1

chromosome 6 open reading 587 0,0007089 0,0657513 283,5 180,5 1,571 C6orf120 frame 120

NADH dehydrogenas e (ubiquinone) flavoprotein 3, 715 0,0009305 0,0708877 670,4 426,6 1,571 NDUFV3 10kDa chromosome 11 open reading frame 1025 0,0016531 0,0879972 80,9 51,5 1,571 C11orf1 1

methylthioaden osine 2340 0,0064386 0,1504404 38,5 24,5 1,571 MTAP phosphorylase

alkB, alkylation repair homolog 2569 0,0077272 0,1644335 341 217 1,571 ALKBH7 7 (E. coli)

chromosome 9 open reading 2811 0,0090005 0,1750631 1110,7 706,9 1,571 C9orf105 frame 105 peroxisomal biogenesis 2909 0,0094542 0,177643 134 85,3 1,571 PEX14 factor 14 NIPA-like domain 3630 0,0136394 0,2052986 79,2 50,4 1,571 NPAL3 containing 3 aldehyde dehydrogenas e 3 family, 3923 0,0157266 0,2191822 402,1 255,9 1,571 ALDH3A2 member A2

dual-specificity tyrosine-(Y)- phosphorylatio n regulated 1433 0,0028108 0,1071379 93,6 59,6 1,57 DYRK4 kinase 4 heterogeneous nuclear ribonucleoprot 1443 0,002848 0,107898 16,8 10,7 1,57 HNRPLL ein L-like mannose-6- phosphate receptor (cation 1767 0,0039418 0,1219045 1578,1 1004,9 1,57 M6PR dependent) CDNA FLJ25731 fis, clone 4879 0,0232514 0,2605398 24,8 15,8 1,57 NA TST05584

CDNA FLJ31635 fis, clone 5414 0,0279528 0,2822902 370,6 236,1 1,57 NA NT2RI2003420 Germ cell-less homolog 1 5677 0,0303203 0,2916051 68 43,3 1,57 GMCL1 (Drosophila) hypothetical protein 6262 0,0360804 0,3150265 57,3 36,5 1,57 LOC145842 LOC145842 DCP1 decapping enzyme homolog B (S. 6332 0,0368113 0,3178238 101,4 64,6 1,57 DCP1B cerevisiae)

farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltra nstransferase, geranyltranstra 7344 0,0475816 0,354238 431,7 275 1,57 FDPS nsferase) CKLF-like MARVEL transmembran e domain 1455 0,002879 0,1081851 868,7 553,8 1,569 CMTM7 containing 7

transmembran 2091 0,0053067 0,1387424 287 182,9 1,569 TMEM41B e protein 41B neurofibromin 2 (bilateral acoustic 4528 0,0204668 0,2471223 18,2 11,6 1,569 NF2 neuroma)

RAB3 GTPase activating protein subunit 2 (non- 494 0,0005653 0,0624087 129,2 82,4 1,568 RAB3GAP2 catalytic) COX18 cytochrome c oxidase assembly homolog (S. 1120 0,0019274 0,0940898 237,2 151,3 1,568 COX18 cerevisiae) programmed 3571 0,013319 0,203925 81,7 52,1 1,568 PDCD2 cell death 2 mitochondrial GTPase 1 homolog (S. 1462 0,0029299 0,1093314 69,4 44,3 1,567 MTG1 cerevisiae)

chromosome 9 open reading 3017 0,0101121 0,1832002 56,1 35,8 1,567 C9orf103 frame 103 cardiolipin 3707 0,0140993 0,2079523 284,8 181,8 1,567 CRLS1 synthase 1 zinc finger 4183 0,0177217 0,2316095 60 38,3 1,567 ZNF564 protein 564 4736 0,0220889 0,2549849 15,2 9,7 1,567 NA NA PHD finger 5017 0,0244687 0,2666586 164,8 105,2 1,567 PHF6 protein 6 CDNA: FLJ23063 fis, clone 7497 0,0491185 0,3582172 43,4 27,7 1,567 NA LNG04745 CDNA FLJ34482 fis, clone HLUNG20040 814 0,0011369 0,0763636 277,1 176,9 1,566 NA 67 chloride channel CLIC- 1394 0,0026824 0,1052072 84,7 54,1 1,566 CLCC1 like 1

Full-length cDNA clone CS0DB002YP 18 of Neuroblastoma Cot 10- normalized of Homo sapiens (human) /// Phosphate cytidylyltransfe rase 2, ethanolamine /// Phosphate cytidylyltransfe rase 2, 2268 0,0061193 0,1475188 64,2 41 1,566 PCYT2 ethanolamine activating signal cointegrator 1 complex subunit 3-like 1 /// activating signal cointegrator 1 complex 2410 0,0068415 0,1552112 863,9 551,8 1,566 ASCC3L1 subunit 3-like 1 pyrroline-5- carboxylate reductase family, member 2936 0,0096506 0,1796709 129,8 82,9 1,566 PYCR2 2 RNA guanylyltransfe rase and 5@#$%&- 2983 0,0099253 0,1818173 59,2 37,8 1,566 RNGTT phosphatase Transcribed 3605 0,0134881 0,2043749 15,5 9,9 1,566 NA locus solute carrier family 16, member 5 (monocarboxyli c acid 1725 0,0037743 0,1195727 51,5 32,9 1,565 SLC16A5 transporter 6) mitogen- activated protein kinase associated 2153 0,0055746 0,1413783 263,8 168,6 1,565 MAPKAP1 protein 1

COX15 homolog, cytochrome c oxidase assembly 2184 0,0057008 0,1426225 172,8 110,4 1,565 COX15 protein (yeast)

sphingomyelin phosphodieste rase 1, acid lysosomal (acid sphingomyelin 5419 0,0280292 0,2827716 38,5 24,6 1,565 SMPD1 ase) nuclear receptor 6898 0,0426439 0,3379944 10,8 6,9 1,565 NCOA2 coactivator 2 Virus-induced signaling 3697 0,0140246 0,2073717 198,1 126,7 1,564 VISA adapter protein phosphatase 1, regulatory 3933 0,0158136 0,219791 802,7 513,1 1,564 PPP1R7 subunit 7 misato homolog 1 (Drosophila) /// MSTO1 /// similar to 4296 0,0186004 0,2367265 54,6 34,9 1,564 LOC731059 misato Hypothetical protein 4385 0,0193673 0,241484 28 17,9 1,564 LOC339803 LOC339803 adenylate 4614 0,0211575 0,2506184 84,3 53,9 1,564 ADCY3 cyclase 3 transmembran e and tetratricopeptid e repeat 4823 0,0227718 0,2581481 43 27,5 1,564 TMTC2 containing 2 elaC homolog 879 0,0012737 0,0792042 16,1 10,3 1,563 ELAC1 1 (E. coli) transformation/ transcription domain- associated 1180 0,0020757 0,0961653 167,6 107,2 1,563 TRRAP protein

WD repeat and SOCS box- containing 1 /// similar to WSB1 /// ribosomal 1461 0,0029196 0,1092602 18,6 11,9 1,563 LOC654170 protein L34 tetratricopeptid e repeat 4326 0,0188033 0,2376045 102,5 65,6 1,563 TTC17 domain 17 547 0,000636 0,0635709 50 32 1,562 NA NA family with sequence similarity 119, 1338 0,0025413 0,1036037 108,1 69,2 1,562 FAM119B member B phosphoinositi de-3-kinase, class 2, alpha 3680 0,013929 0,2069478 145,9 93,4 1,562 PIK3C2A polypeptide baculoviral IAP repeat- containing 6 510 0,0005878 0,0630156 350,6 224,6 1,561 BIRC6 (apollon) CDNA clone IMAGE:528600 1729 0,0037923 0,1199213 21,7 13,9 1,561 NA 5 CDNA clone IMAGE:482080 3446 0,0126112 0,1999997 10,3 6,6 1,561 NA 9 hypothetical protein 3756 0,0143981 0,209589 37,3 23,9 1,561 LOC254128 LOC254128 hypothetical protein 4227 0,0180517 0,2334877 599,8 384,3 1,561 LOC158960 BC009467 proline synthetase co- transcribed homolog 7208 0,0460752 0,3494369 530,2 339,7 1,561 PROSC (bacterial) Transcribed 2116 0,0053973 0,1393516 28,7 18,4 1,56 NA locus coronin, actin binding protein, 2512 0,0073731 0,1604794 109,8 70,4 1,56 CORO1B 1B chromosome 16 open reading frame 2631 0,0080695 0,167497 91,4 58,6 1,56 C16orf57 57 haloacid dehalogenase- like hydrolase domain 3493 0,0128854 0,2016917 333 213,4 1,56 HDHD2 containing 2

bromodomain and WD repeat domain 4178 0,0176855 0,2314396 449,3 288,1 1,56 BRWD2 containing 2 solute carrier family 38, 5442 0,0281601 0,2828723 1204,7 772,1 1,56 SLC38A6 member 6 1226 0,0022004 0,0980283 667,9 428,3 1,559 GYG1 glycogenin 1 asparagine- linked glycosylation 8 homolog (S. cerevisiae, alpha-1,3- glucosyltransfe 1278 0,00235 0,100537 425,3 272,8 1,559 ALG8 rase) BCL2- associated 2504 0,0073184 0,1597509 319,7 205,1 1,559 BAG4 athanogene 4 DnaJ (Hsp40) homolog, subfamily B, 2812 0,0090056 0,1750784 593,7 380,9 1,559 DNAJB11 member 11 zinc finger, FYVE domain 1121 0,0019336 0,0943083 56,4 36,2 1,558 ZFYVE21 containing 21 CDNA FLJ11174 fis, clone PLACE100736 2566 0,0076747 0,1635285 204,2 131,1 1,558 NA 7

glucocorticoid receptor DNA 2621 0,0080258 0,1674211 150,5 96,6 1,558 GRLF1 binding factor 1

required for meiotic nuclear division 1 homolog (S. 6155 0,0350223 0,3111039 67,3 43,2 1,558 RMND1 cerevisiae)

chromosome 1 open reading 1108 0,0018762 0,0925823 1083,3 695,6 1,557 C1orf43 frame 43 Mitogen- activated protein kinase kinase kinase 1261 0,0022815 0,0987873 127,2 81,7 1,557 MAP3K15 15 protein tyrosine phosphatase- like A domain 1470 0,0029444 0,1094764 1142,3 734,3 1,556 PTPLAD1 containing 1 WD repeat 2563 0,0076602 0,1634106 93,2 59,9 1,556 WDR46 domain 46 heparan sulfate 2-O- sulfotransferas 2782 0,0088204 0,1733484 299 192,2 1,556 HS2ST1 e 1 solute carrier family 26 (sulfate transporter), 5690 0,0303647 0,2916051 131,5 84,5 1,556 SLC26A2 member 2 inositol 1,4,5- trisphosphate 5887 0,0321465 0,2985081 16,8 10,8 1,556 ITPKB 3-kinase B MRNA full length insert cDNA clone EUROIMAGE 6037 0,0337277 0,3053707 11,2 7,2 1,556 NA 839551 2016 0,0049558 0,1343033 446 286,9 1,555 NA NA DEP domain 3134 0,0108246 0,1888433 42,3 27,2 1,555 DEPDC5 containing 5 O- sialoglycoprote in endopeptidase- 3269 0,0115783 0,1936505 74,8 48,1 1,555 OSGEPL1 like 1 aspartylglucos 5809 0,0313604 0,2951678 134 86,2 1,555 AGA aminidase 1863 0,0043117 0,1264829 49,1 31,6 1,554 NA NA kelch-like 9 2610 0,0079645 0,1668425 104,4 67,2 1,554 KLHL9 (Drosophila) myxovirus (influenza virus) resistance 2 2953 0,0097398 0,1802684 122 78,5 1,554 MX2 (mouse)

transmembran 2971 0,0098209 0,180733 63,4 40,8 1,554 TMEM55A e protein 55A ChaC, cation transport regulator homolog 2 (E. 3441 0,0125723 0,1997647 11,5 7,4 1,554 CHAC2 coli) chromosome 17 open reading frame 3452 0,0126336 0,1999997 118,4 76,2 1,554 C17orf60 60 fucosyltransfer ase 8 (alpha (1,6) fucosyltransfer 4624 0,0212242 0,2509234 15,7 10,1 1,554 FUT8 ase) single-strand- selective monofunctional uracil-DNA 6885 0,0424679 0,3372128 38,7 24,9 1,554 SMUG1 glycosylase 1 chromosome 13 open reading frame 1430 0,0028069 0,1071379 134,3 86,5 1,553 C13orf8 8 hypothetical protein 698 0,0009034 0,070427 13,5 8,7 1,552 FLJ33630 LOC644873 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1610 0,0034126 0,1158906 453 291,8 1,552 PSMD10 10

transmembran e and coiled- 2269 0,0061374 0,14789 92,2 59,4 1,552 TMCO7 coil domains 7 mitochondrial ribosomal 3796 0,014769 0,2126667 227,8 146,8 1,552 MRPL17 protein L17 ras homolog gene family, 6483 0,0381626 0,3218118 1107,5 713,5 1,552 RHOQ member Q chromosome 14 open reading frame 6887 0,0424813 0,3372128 135,8 87,5 1,552 C14orf106 106 methylmalonyl Coenzyme A 7518 0,0493928 0,3592114 55,1 35,5 1,552 MUT mutase

chromosome 2 open reading 760 0,0010259 0,0738041 325,4 209,8 1,551 C2orf30 frame 30 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, 2041 0,0050848 0,1362133 217,5 140,2 1,551 SMARCA2 member 2 nuclear factor of activated T- cells, cytoplasmic, calcineurin- 6966 0,0435317 0,3415944 154,5 99,6 1,551 NFATC3 dependent 3 phosphogluco 750 0,0010023 0,0730677 296,9 191,6 1,55 PGM2 mutase 2 GLE1 RNA export mediator-like 2917 0,0094926 0,1779252 72,4 46,7 1,55 GLE1L (yeast) chromosome 12 open reading frame 3834 0,0150875 0,2151458 98,3 63,4 1,55 C12orf23 23 5007 0,0243729 0,2661451 341,1 220,1 1,55 CALU calumenin chromosome 14 open reading frame 6853 0,0422021 0,3366308 226,9 146,4 1,55 C14orf101 101 hypothetical protein 6932 0,0430432 0,3394534 21,7 14 1,55 MGC13098 MGC13098

337 0,0003423 0,0552439 75,3 48,6 1,549 SELI selenoprotein I WD repeat 1486 0,0029808 0,1095772 176,4 113,9 1,549 WDR61 domain 61 Transcribed 1681 0,0036233 0,1177064 33 21,3 1,549 NA locus chromosome 12 open reading frame 3387 0,0123018 0,1984223 321,8 207,8 1,549 C12orf62 62 Transcribed 349 0,000357 0,0556372 6,5 4,2 1,548 NA locus Programmed 2058 0,0051574 0,1368599 53,1 34,3 1,548 PDCD6 cell death 6 histone cluster 2218 0,0058544 0,1441488 9,6 6,2 1,548 HIST1H4H 1, H4h

histone cluster 2992 0,0099884 0,1824977 24,3 15,7 1,548 HIST1H2BI 1, H2bi coatomer protein complex, 3036 0,0102284 0,1842022 67,8 43,8 1,548 COPA subunit alpha zinc finger 6234 0,0358548 0,314447 40,1 25,9 1,548 ZNF193 protein 193 peroxisome biogenesis 6492 0,0382878 0,322196 16,1 10,4 1,548 PEX1 factor 1 Zinc finger protein 724 1493 0,0029988 0,1098187 13,3 8,6 1,547 ZNF724P pseudogene

transient receptor potential cation channel, subfamily M, 612 0,0007376 0,0657513 64,3 41,6 1,546 TRPM7 member 7

chromosome 5 open reading 3271 0,0116081 0,1940302 122 78,9 1,546 C5orf22 frame 22 coiled-coil domain 6086 0,0342362 0,3075689 20,1 13 1,546 CCDC41 containing 41 DIM1 dimethyladeno sine transferase 1- like (S. 327 0,0003344 0,0552439 119 77 1,545 DIMT1L cerevisiae) mitochondrial ribosomal 838 0,0012117 0,0790355 456 295,2 1,545 MRPL15 protein L15 anaphase promoting complex 2363 0,006596 0,1525742 102,3 66,2 1,545 ANAPC5 subunit 5 mitochondrial ribosomal protein L9 /// mitochondrial ribosomal 2517 0,0073995 0,1607341 109,7 71 1,545 MRPL9 protein L9 Transcribed 4375 0,0192662 0,2407725 36,3 23,5 1,545 NA locus

solute carrier family 39 (zinc transporter), 7489 0,0490184 0,357869 24,1 15,6 1,545 SLC39A9 member 9 zyg-11 homolog B (C. 7533 0,0495447 0,3594767 137 88,7 1,545 ZYG11B elegans) histocompatibil 1833 0,0041752 0,1245272 565,3 366,1 1,544 HM13 ity (minor) 13

3580 0,0133712 0,2042096 24,4 15,8 1,544 SNX5 sorting nexin 5 transforming growth factor, beta receptor II 4033 0,016636 0,2255327 701,7 454,5 1,544 TGFBR2 (70/80kDa) 385 0,0004087 0,0577756 210,5 136,4 1,543 CALR Calreticulin SET domain, 2572 0,0077538 0,1648285 77,3 50,1 1,543 SETDB1 bifurcated 1 major histocompatibili ty complex, 3350 0,0121343 0,1980426 212,3 137,6 1,543 MR1 class I-related Aristaless-like 3840 0,0151495 0,2157028 21,3 13,8 1,543 ALX3 homeobox 3

polymerase (RNA) III (DNA directed) 4294 0,0185876 0,236667 76,7 49,7 1,543 POLR3B polypeptide B survival of motor neuron 1, telomeric /// survival of SMN1 /// motor neuron 6273 0,0362093 0,3155976 124,8 80,9 1,543 SMN2 2, centromeric chromosome 7 open reading frame 28A /// chromosome 7 C7orf28A /// open reading 7053 0,04438 0,3440115 304,5 197,4 1,543 C7orf28B frame 28B

coiled-coil- helix-coiled-coil- helix domain 700 0,0009046 0,070427 232,8 151 1,542 CHCHD8 containing 8 l(3)mbt-like 2 1460 0,0029146 0,1091478 68,6 44,5 1,542 L3MBTL2 (Drosophila) XTP3- transactivated 1981 0,0047871 0,1321225 347,3 225,3 1,542 XTP3TPA protein A 6770 0,0413909 0,3342758 31 20,1 1,542 NA NA HECT domain 1276 0,0023369 0,1001319 131 85 1,541 HECTD3 containing 3

malate dehydrogenas e 2, NAD 1630 0,0034695 0,1161645 99,4 64,5 1,541 MDH2 (mitochondrial)

chromosome 4 open reading 4115 0,0172252 0,2288456 89,4 58 1,541 C4orf27 frame 27

chromosome 5 open reading 4550 0,0206159 0,2476563 20,5 13,3 1,541 C5orf22 frame 22 FCH domain 4646 0,0213993 0,251831 72,6 47,1 1,541 FCHO1 only 1 solute carrier family 25, 4882 0,0232974 0,2609147 399,9 259,5 1,541 SLC25A40 member 40 chromosome 14 open reading frame 5051 0,0247467 0,2678729 22,8 14,8 1,541 C14orf103 103 NDRG family member 3 /// NDRG family 6852 0,0421956 0,3366308 92,9 60,3 1,541 NDRG3 member 3 2355 0,0065443 0,1519361 192,5 125 1,54 SVH SVH protein Transcribed 2724 0,0085209 0,1709847 131,5 85,4 1,54 NA locus zinc finger 3775 0,0145599 0,2108775 7,7 5 1,54 ZNF616 protein 616

Full-length cDNA clone CS0DC007YG 11 of Neuroblastoma Cot 25- normalized of Homo sapiens 4328 0,0188116 0,2376045 153,8 99,9 1,54 NA (human) hypothetical protein 4600 0,0209995 0,2495973 166 107,8 1,54 FLJ14981 FLJ14981 dedicator of 5057 0,0247902 0,2680253 321 208,5 1,54 DOCK8 cytokinesis 8 protein disulfide isomerase family A, member 4 /// protein disulfide isomerase family A, 1988 0,0048322 0,1328977 419 272,2 1,539 PDIA4 member 4 nuclear VCP- 2083 0,0052714 0,1383062 60,8 39,5 1,539 NVL like zinc finger 2386 0,0066973 0,1534681 23,7 15,4 1,539 ZNF545 protein 545

UDP-N-acetyl- alpha-D- galactosamine: polypeptide N- acetylgalactos aminyltransfer ase 1 (GalNAc- 2951 0,0097118 0,1799365 520,9 338,4 1,539 GALNT1 T1)

alcohol dehydrogenas e 5 (class III), 3040 0,0102586 0,1844024 115 74,7 1,539 ADH5 chi polypeptide 4038 0,0166891 0,2259544 97,9 63,6 1,539 CCNG2 cyclin G2

FK506 binding 4768 0,0223714 0,2565345 822,3 534,2 1,539 FKBP5 protein 5

SNF8, ESCRT- II complex subunit, homolog (S. 5242 0,0264316 0,2755518 489,1 317,8 1,539 SNF8 cerevisiae) enoyl Coenzyme A hydratase domain 5590 0,0294678 0,2881284 156,2 101,5 1,539 ECHDC1 containing 1

solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), 2591 0,0078621 0,1659052 28 18,2 1,538 SLC25A16 member 16 tetratricopeptid e repeat 2900 0,0093888 0,1769729 198,3 128,9 1,538 TTC13 domain 13 Transcribed 4279 0,0184581 0,2358049 20 13 1,538 NA locus synaptosomal- associated 6132 0,0347873 0,3101754 164,9 107,2 1,538 SNAP23 protein, 23kDa WD repeat 6302 0,0365362 0,3169554 120 78 1,538 WDR70 domain 70 chromosome 14 open reading frame 1159 0,0020183 0,0952119 950,7 618,7 1,537 C14orf100 100 transmembran 1696 0,0036649 0,1181476 734,6 477,8 1,537 TMEM4 e protein 4

twinfilin, actin- binding protein, homolog 2 1853 0,004272 0,1259529 333,6 217 1,537 TWF2 (Drosophila) protein tyrosine phosphatase- like A domain containing 1 /// similar to butyrate- PTPLAD1 /// induced 2836 0,0091044 0,1754434 662,7 431,2 1,537 LOC732402 transcript 1

FK506 binding protein 1A, 4017 0,0165074 0,2246574 220,1 143,2 1,537 FKBP1A 12kDa Phosphatidic acid phosphatase 1116 0,0019101 0,0935795 28,1 18,3 1,536 PPAP2B type 2B coenzyme Q5 homolog, methyltransfer ase (S. 1850 0,0042672 0,1259529 280,4 182,6 1,536 COQ5 cerevisiae) protein tyrosine phosphatase- like A domain 2158 0,0055834 0,1413783 1112,5 724,4 1,536 PTPLAD1 containing 1 interleukin 16 (lymphocyte chemoattracta 3045 0,0102998 0,1848973 63,9 41,6 1,536 IL16 nt factor) hypothetical 3673 0,0139026 0,2069266 49,6 32,3 1,536 LOC642852 LOC642852 RNA binding motif protein 7296 0,0470937 0,3528789 154,5 100,6 1,536 RBM35B 35B apolipoprotein B mRNA editing enzyme, catalytic polypeptide- 1093 0,0018238 0,0912317 180,5 117,6 1,535 APOBEC3G like 3G NLR family 1475 0,0029632 0,109553 41,9 27,3 1,535 NLRX1 member X1 2402 0,0067763 0,154244 184,3 120,1 1,535 DNM1L dynamin 1-like proteasome (prosome, macropain) subunit, beta 3398 0,0123482 0,1984223 422,9 275,5 1,535 PSMB5 type, 5 zinc finger 3462 0,012667 0,2000445 6,6 4,3 1,535 ZNF594 protein 594 non imprinted in Prader- Willi/Angelman 3718 0,0141658 0,2082838 50,2 32,7 1,535 NIPA1 syndrome 1 hypothetical protein 4260 0,0182757 0,2345596 244,7 159,4 1,535 FLJ12118 FLJ12118 N- acetyltransfera 4603 0,0210522 0,2500606 138,8 90,4 1,535 NAT10 se 10 chromosome 17 open reading frame 737 0,0009718 0,0720258 20,4 13,3 1,534 C17orf75 75

phosphatidylin ositol binding clathrin assembly 915 0,0013571 0,0810038 440,3 287 1,534 PICALM protein

zinc finger and BTB domain 6015 0,0335069 0,3045583 25 16,3 1,534 ZBTB26 containing 26

CDNA FLJ11313 fis, clone PLACE101010 6, highly similar to Homo sapiens mRNA; cDNA DKFZp586M14 6387 0,0371806 0,318279 26,7 17,4 1,534 NA 18 zinc finger 6639 0,0397311 0,3272026 99,7 65 1,534 ZNF641 protein 641 2215 0,0058423 0,1441488 1593,2 1039,1 1,533 CTSD cathepsin D APEX nuclease (multifunctional DNA repair 2734 0,0085849 0,1716407 1171,2 764,2 1,533 APEX1 enzyme) 1 general transcription 3030 0,0101694 0,1835023 1589,9 1036,9 1,533 GTF3A factor IIIA glutamyl-prolyl- tRNA 4537 0,0205416 0,2474965 510 332,7 1,533 EPRS synthetase

tyrosyl-tRNA synthetase 2 5637 0,0298574 0,2895961 189,3 123,5 1,533 YARS2 (mitochondrial) SET translocation (myeloid leukemia- 688 0,0008833 0,0701954 1036,9 677 1,532 SET associated) cytokine-like nuclear factor 756 0,0010176 0,0735843 142,9 93,3 1,532 N-PAC n-pac protein O- linked mannose beta1,2-N- acetylglucosa minyltransferas 774 0,0010661 0,075254 54,7 35,7 1,532 POMGNT1 e PRP18 pre- mRNA processing factor 18 homolog (S. 1960 0,0046857 0,1307095 11,8 7,7 1,532 PRPF18 cerevisiae) hypothetical protein 2521 0,0074267 0,1610149 108,9 71,1 1,532 LOC134145 LOC134145 2728 0,0085313 0,1709856 29,1 19 1,532 CUL3 cullin 3 ceroid- lipofuscinosis, neuronal 6, late infantile, 1260 0,002278 0,0987873 94,6 61,8 1,531 CLN6 variant triggering receptor expressed on myeloid cells- 1744 0,0038397 0,1203759 61,1 39,9 1,531 TREML1 like 1 tumor protein p53 inducible nuclear protein 3655 0,0137693 0,205933 218,3 142,6 1,531 TP53INP1 1 4398 0,0194934 0,2422309 120 78,4 1,531 KIAA1279 KIAA1279 cell cycle 5583 0,0294213 0,2880914 40,1 26,2 1,531 CCPG1 progression 1 CTTNBP2 N- 5610 0,0296486 0,2889396 37,5 24,5 1,531 CTTNBP2NL terminal like

transmembran 5617 0,0296886 0,2889396 809,6 528,8 1,531 TMEM126A e protein 126A

A kinase (PRKA) anchor 382 0,0004064 0,0577756 223,5 146,1 1,53 AKAP1 protein 1

signal sequence receptor, alpha (translocon- associated 457 0,0004991 0,0597118 422,6 276,2 1,53 SSR1 protein alpha) mevalonate kinase (mevalonic 1699 0,0036811 0,1184604 30,3 19,8 1,53 MVK aciduria) FK506 binding protein 1A, 2253 0,006044 0,1466736 25,4 16,6 1,53 FKBP1A 12kDa F-box protein 2815 0,0090166 0,1750784 90,6 59,2 1,53 FBXO22 22 2825 0,0090577 0,175254 561,4 367 1,53 NA NA lymphocyte 5962 0,0329191 0,3017912 23,1 15,1 1,53 LY9 antigen 9 ATP citrate 2228 0,0058762 0,1442016 1106,8 723,9 1,529 ACLY lyase Phosphoinositi de-3-kinase, 2959 0,0097644 0,1804053 23,7 15,5 1,529 PIK3C3 class 3

UDP-N-acetyl- alpha-D- galactosamine: polypeptide N- acetylgalactos aminyltransfer ase 10 4492 0,0201934 0,2457406 54,6 35,7 1,529 GALNT10 (GalNAc-T10) hypothetical RP11- protein 4582 0,0208689 0,2489466 18,5 12,1 1,529 262H14.4 MGC21881 eukaryotic translation initiation factor 351 0,0003592 0,0556372 230,2 150,7 1,528 EIF5B 5B

small nuclear RNA activating complex, polypeptide 5, 1781 0,0039906 0,1224818 173,7 113,7 1,528 SNAPC5 19kDa solute carrier family 25 (mitochondrial carrier; citrate transporter), 5816 0,0314426 0,2955493 189,8 124,2 1,528 SLC25A1 member 1

transmembran 6372 0,0370948 0,3182128 194,8 127,5 1,528 TMEM106B e protein 106B tRNA splicing endonuclease 2 homolog (S. 2190 0,0057212 0,1428341 58,5 38,3 1,527 TSEN2 cerevisiae) SYS1 Golgi- localized integral membrane protein homolog (S. 5049 0,0247396 0,2678729 158,5 103,8 1,527 SYS1 cerevisiae) steroid sulfatase (microsomal), arylsulfatase 7378 0,0479062 0,3549593 28,1 18,4 1,527 STS C, isozyme S chromatin modifying 969 0,0014913 0,0839343 435,6 285,4 1,526 CHMP5 protein 5 peroxiredoxin 1643 0,0034912 0,1161645 1030 675 1,526 PRDX6 6 apoptosis 2173 0,0056363 0,1417702 471,4 308,9 1,526 API5 inhibitor 5 ATG10 autophagy related 10 homolog (S. 2380 0,006658 0,1529316 14,8 9,7 1,526 ATG10 cerevisiae)

NADH dehydrogenas e (ubiquinone) 1, alpha/beta subcomplex, 1, 2508 0,0073304 0,1598045 2084,8 1365,9 1,526 NDUFAB1 8kDa ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 2687 0,008331 0,169519 1942 1272,3 1,526 ATP5G3 (subunit 9) RAN binding 3146 0,010912 0,1895776 83,3 54,6 1,526 RANBP5 protein 5 RIO kinase 2 6984 0,0436756 0,341888 32,5 21,3 1,526 RIOK2 (yeast)

DEAH (Asp- Glu-Ala-His) box 484 0,0005473 0,0615795 224,9 147,5 1,525 DHX29 polypeptide 29 chromosome 22 open reading frame 926 0,0013907 0,082042 434,5 285 1,525 C22orf9 9 4014 0,0164819 0,2245012 151,6 99,4 1,525 MTX2 metaxin 2 MORC family CW-type zinc 5408 0,0279149 0,2821988 160,7 105,4 1,525 MORC2 finger 2

glutamyl-tRNA synthetase 2 (mitochondrial) 6295 0,0364458 0,3165487 69,1 45,3 1,525 EARS2 (putative) vesicle- associated membrane protein 8 1110 0,0018873 0,092918 2883,4 1891,6 1,524 VAMP8 (endobrevin) phosphatidic acid phosphatase type 2 domain 1926 0,0045567 0,1293549 104,7 68,7 1,524 PPAPDC1B containing 1B mitochondrial ribosomal 2526 0,0074445 0,1611354 314 206 1,524 MRPS16 protein S16 phosphoinositi de-3-kinase, class 2, alpha 2752 0,0086931 0,1726761 97,2 63,8 1,524 PIK3C2A polypeptide

Guanine nucleotide binding protein (G protein), q 3813 0,0148881 0,2134446 408 267,7 1,524 GNAQ polypeptide general transcription 4925 0,0236255 0,262279 1475,3 967,9 1,524 GTF3A factor IIIA similar to RIKEN cDNA A430101B06 5256 0,0265414 0,2760755 31,7 20,8 1,524 MGC13017 gene

SH3 domain containing, Ysc84-like 1 1229 0,0022049 0,0980283 180,6 118,6 1,523 SH3YL1 (S. cerevisiae) mitochondrial ribosomal 1252 0,0022597 0,0986109 130,8 85,9 1,523 MRPS26 protein S26 glycoprotein (transmembran 1296 0,0024226 0,1022034 5527,9 3629,8 1,523 GPNMB e) nmb chromosome 19 open reading frame 1481 0,0029675 0,109553 42,2 27,7 1,523 C19orf39 39 integrator complex 2032 0,0050405 0,1356247 114,8 75,4 1,523 RC74 subunit 9 family with sequence similarity 55, 4179 0,0176921 0,2314466 33,8 22,2 1,523 FAM55C member C General transcription factor IIIC, polypeptide 2, 4364 0,0191524 0,2399536 23 15,1 1,523 GTF3C2 beta 110kDa farnesyl- diphosphate farnesyltransfe 4869 0,0231672 0,2599793 782,8 514,1 1,523 FDFT1 rase 1 N- myristoyltransf 5658 0,0301206 0,2910113 30,3 19,9 1,523 NMT1 erase 1 Intracisternal A particle- promoted 1364 0,002598 0,1040748 10,2 6,7 1,522 IPP polypeptide zinc finger, BED-type 1514 0,0030746 0,1110329 168,2 110,5 1,522 ZBED3 containing 3 1693 0,0036477 0,1178015 267,8 175,9 1,522 KIAA0196 KIAA0196 2201 0,0057799 0,1435306 14 9,2 1,522 NA NA ATP-binding cassette, sub- family C (CFTR/MRP), 2399 0,0067619 0,1541087 191,5 125,8 1,522 ABCC10 member 10 STT3, subunit of the oligosaccharylt ransferase complex, homolog A (S. 3107 0,0106586 0,1875632 294,3 193,4 1,522 STT3A cerevisiae) solute carrier family 45, 3135 0,0108343 0,1889066 44,3 29,1 1,522 SLC45A3 member 3 peroxisomal biogenesis 4656 0,0214639 0,2520487 175,5 115,3 1,522 PEX11B factor 11B mindbomb homolog 1 6942 0,0432402 0,3404595 14 9,2 1,522 MIB1 (Drosophila) hypothetical protein 7324 0,0473445 0,3534354 7 4,6 1,522 LOC144874 LOC144874 ganglioside- induced differentiation- associated 525 0,0006117 0,0635709 18,1 11,9 1,521 GDAP1 protein 1 1943 0,0046185 0,1299198 32,1 21,1 1,521 HK2 hexokinase 2 DnaJ (Hsp40) homolog, subfamily A, 3691 0,013999 0,207368 260,8 171,5 1,521 DNAJA3 member 3 electron- transferring- flavoprotein dehydrogenas 4475 0,0200031 0,2443954 108 71 1,521 ETFDH e ethanolamine 4571 0,0207818 0,2485769 229,5 150,9 1,521 ETNK1 kinase 1

CDNA FLJ43322 fis, clone 4826 0,0228319 0,2586565 10,8 7,1 1,521 NA NT2RI2027975 tripartite motif- 6732 0,041013 0,3330679 64,2 42,2 1,521 TRIM68 containing 68 microsomal glutathione S- 2048 0,0051116 0,1364632 2429,1 1598 1,52 MGST3 transferase 3 RNA binding motif protein 4110 0,0171949 0,2287173 734,1 482,9 1,52 RBM8A 8A SEC23 interacting 4153 0,0174853 0,2301972 106,4 70 1,52 SEC23IP protein RuvB-like 1 (E. 5432 0,0281158 0,2828411 92,1 60,6 1,52 RUVBL1 coli) 371 0,0003946 0,0577756 1849,4 1217,8 1,519 RPN2 ribophorin II ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein 1838 0,0042184 0,1254704 685,2 451,1 1,519 RAC2 Rac2)

chromosome 1 open reading 2200 0,0057769 0,1435306 68,2 44,9 1,519 C1orf19 frame 19

mitogen- activated protein-binding protein- interacting 2344 0,0064699 0,1509137 650,1 428,4 1,518 MAPBPIP protein Homeodomain interacting protein kinase 7377 0,0478936 0,3549593 68 44,8 1,518 HIPK2 2 activating signal cointegrator 1 complex 674 0,0008606 0,069812 73,4 48,4 1,517 ASCC1 subunit 1 tRNA selenocysteine associated 1331 0,0025214 0,1035459 162,8 107,3 1,517 TRSPAP1 protein 1 3469 0,0127021 0,2001981 32 21,1 1,517 NA NA peroxisomal biogenesis 6213 0,0355875 0,3131734 392,7 258,9 1,517 PEX19 factor 19

translocated promoter region (to activated MET 7571 0,0499876 0,3609756 35,2 23,2 1,517 TPR oncogene)

FGFR1 oncogene partner /// chromosome 9 FGFR1OP /// open reading 2313 0,0063354 0,149757 41,4 27,3 1,516 C9orf4 frame 4 opsin 3 (encephalopsin , panopsin) /// opsin 3 (encephalopsin 2534 0,0074995 0,1618134 178,4 117,7 1,516 OPN3 , panopsin) zinc finger 3052 0,0103529 0,1854668 32,6 21,5 1,516 ZNF789 protein 789 translocation 4365 0,0191621 0,2400201 193,1 127,5 1,515 TLOC1 protein 1 CDNA FLJ39218 fis, clone OCBBF200666 7341 0,0475521 0,3541631 44,1 29,1 1,515 NA 0

7409 0,0482321 0,3558862 39,7 26,2 1,515 ARSD arylsulfatase D chromosome 14 open reading frame 668 0,0008521 0,0697147 437,5 288,9 1,514 C14orf129 129 thioredoxin domain 2337 0,0064183 0,1501586 640,5 423 1,514 TXNDC14 containing 14 germ cell-less homolog 1 (Drosophila) /// germ cell-less homolog 1 GMCL1 /// (Drosophila)- 4405 0,0195253 0,2422309 22,4 14,8 1,514 GMCL1L like SET domain and mariner transposase 4771 0,0224004 0,2567055 58 38,3 1,514 SETMAR fusion gene Heterogeneou s nuclear ribonucleoprot 5734 0,030828 0,2937838 85,1 56,2 1,514 HNRPA0 ein A0 DNA directed RNA polymerase II polypeptide J- 7048 0,0443124 0,3437543 83,9 55,4 1,514 POLR2J2 related gene

apoptosis- inducing, TAF9- 7319 0,0472909 0,3532764 36,8 24,3 1,514 APITD1 like domain 1 zinc finger 7364 0,0478032 0,3547819 65,7 43,4 1,514 ZNF451 protein 451 WD repeat 1369 0,0026284 0,1048471 1580,9 1044,6 1,513 WDR1 domain 1 major histocompatibili ty complex, 2870 0,0092524 0,1762631 63,4 41,9 1,513 MR1 class I-related Yip1 domain family, member 2897 0,0093589 0,176607 47,5 31,4 1,513 YIPF6 6 WD repeats and SOF1 domain 4498 0,0202305 0,2459099 79 52,2 1,513 WDSOF1 containing

transmembran 5522 0,0289425 0,2864915 155,7 102,9 1,513 TMEM128 e protein 128 zinc finger 6104 0,0344713 0,3086141 138 91,2 1,513 ZNF294 protein 294 similar to serine/threonin e/tyrosine interacting 563 0,0006625 0,064104 18,6 12,3 1,512 LOC730432 protein 1237 0,0022205 0,0980838 577,6 382 1,512 SNX1 sorting nexin 1 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex- associated 1333 0,0025261 0,1035792 152,6 100,9 1,512 IKBKAP protein 1797 0,0040577 0,1233958 146,7 97 1,512 XPO5 exportin 5 CKLF-like MARVEL transmembran e domain 4052 0,0167888 0,2265369 25,4 16,8 1,512 CMTM7 containing 7 ribonuclease 4737 0,0220917 0,2549849 288,3 190,7 1,512 RNASEH1 H1 thioredoxin 4928 0,023664 0,2625354 12,4 8,2 1,512 TXNRD3 reductase 3 chloride channel CLIC- 466 0,000515 0,0602236 60,6 40,1 1,511 CLCC1 like 1 kelch-like 8 722 0,0009385 0,0710699 197,5 130,7 1,511 KLHL8 (Drosophila) glucosidase, beta; acid (includes glucosylcerami dase) /// glucosidase, GBA /// beta; acid, 3774 0,0145586 0,2108775 461,6 305,4 1,511 GBAP pseudogene

chromosome 1 open reading 4062 0,0168413 0,2266524 65,9 43,6 1,511 C1orf107 frame 107 non-SMC element 4 homolog A (S. 4526 0,020457 0,2471223 182,5 120,8 1,511 NSMCE4A cerevisiae) kelch-like 7 5956 0,0328699 0,3016964 165,3 109,4 1,511 KLHL7 (Drosophila) aconitase 2, 1747 0,0038613 0,1208011 584,8 387,3 1,51 ACO2 mitochondrial CDNA clone IMAGE:530291 1866 0,0043321 0,126877 7,4 4,9 1,51 NA 3 phenylalanine- tRNA synthetase- like, beta 1945 0,0046226 0,1299198 246,3 163,1 1,51 FARSLB subunit M-phase phosphoprotei 5471 0,0284493 0,2842101 30,8 20,4 1,51 MPHOSPH9 n 9

coiled-coil domain 5839 0,0316828 0,2966203 168,2 111,4 1,51 CCDC128 containing 128 WW domain containing E3 ubiquitin 6691 0,0404409 0,3304598 37,9 25,1 1,51 WWP2 protein ligase 2 ADP- ribosylation factor guanine nucleotide- exchange factor 1(brefeldin A- 7202 0,0459938 0,3491684 175,3 116,1 1,51 ARFGEF1 inhibited)

glyceronephos phate O- 802 0,0011158 0,0760071 496,4 329 1,509 GNPAT acyltransferase

Integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha 2933 0,0096362 0,1796209 32,6 21,6 1,509 ITGAE polypeptide)

chromosome 9 open reading 3620 0,0135682 0,2049285 219,1 145,2 1,509 C9orf23 frame 23 F-box protein 5830 0,0315825 0,2961433 8,3 5,5 1,509 FBXO30 30 TAF12 RNA polymerase II, TATA box binding protein (TBP)- associated 896 0,0013134 0,0801453 122,6 81,3 1,508 TAF12 factor, 20kDa

chromosome 1 open reading 1426 0,0027926 0,1070725 83,1 55,1 1,508 C1orf19 frame 19

signal recognition 2217 0,0058497 0,1441488 262,6 174,1 1,508 SRP72 particle 72kDa family with sequence similarity 118, 5239 0,0264074 0,2755518 100,6 66,7 1,508 FAM118B member B Cleavage stimulation factor, 3@#$%& pre- RNA, subunit 5602 0,0295875 0,2887713 18,1 12 1,508 CSTF2 2, 64kDa Solute carrier family 37 (glycerol-3- phosphate transporter), 6723 0,04091 0,3327018 9,8 6,5 1,508 SLC37A3 member 3 transmembran 1439 0,0028251 0,1073401 158,5 105,2 1,507 TMEM50B e protein 50B scavenger receptor class 1667 0,0035775 0,1173364 1759,6 1167,9 1,507 SCARB2 B, member 2

glutathione S- 1892 0,0044601 0,128789 43,4 28,8 1,507 GSTM4 transferase M4 transcription 2577 0,0077922 0,1652859 207,9 138 1,507 TFDP1 factor Dp-1 high-mobility 3558 0,0132498 0,2036033 297,7 197,6 1,507 HMG20B group 20B

succinate dehydrogenas e complex, subunit C, integral membrane protein, 15kDa /// similar to succinate dehydrogenas e complex, subunit C SDHC /// isoform 3 3616 0,0135414 0,2047342 391,5 259,8 1,507 LOC642502 precursor CDNA: FLJ21561 fis, clone 5437 0,0281312 0,2828411 43,1 28,6 1,507 NA COL06415 Dedicator of 6226 0,0357428 0,3138833 383,1 254,2 1,507 DOCK5 cytokinesis 5

1046 0,0016912 0,088241 118,1 78,4 1,506 LOC205251 LOC205251

AP1 gamma subunit binding 1922 0,0045512 0,1293549 25 16,6 1,506 AP1GBP1 protein 1 progesterone receptor membrane 2853 0,0091921 0,1761535 73,8 49 1,506 PGRMC2 component 2

chromosome X open reading 4289 0,0185555 0,2365404 202,3 134,3 1,506 CXorf39 frame 39 exosome 5081 0,0250183 0,2692138 193,1 128,2 1,506 EXOSC4 component 4 zinc finger 6298 0,036484 0,3167295 11,9 7,9 1,506 ZNF623 protein 623 CDNA: FLJ21763 fis, clone 462 0,0005079 0,0600598 392,1 260,5 1,505 NA COLF6967 cyclin- dependent 4109 0,0171741 0,2285213 256,5 170,4 1,505 CDK5 kinase 5

5375 0,0275553 0,2802511 1151,2 764,9 1,505 SNX5 sorting nexin 5 zinc binding alcohol dehydrogenas e, domain 7458 0,0487157 0,3570493 56,3 37,4 1,505 ZADH2 containing 2

chromosome 3 open reading 2104 0,0053603 0,1392684 491,5 326,8 1,504 C3orf1 frame 1 solute carrier family 15, 2795 0,0089259 0,1746059 1160,6 771,6 1,504 SLC15A3 member 3 programmed cell death 4 (neoplastic transformation 3602 0,0134758 0,2043749 110,7 73,6 1,504 PDCD4 inhibitor)

chromosome 1 open reading 7391 0,0479927 0,3550265 51 33,9 1,504 C1orf25 frame 25 hypothetical protein LOC348180, 1135 0,0019657 0,0946254 24,5 16,3 1,503 LOC348180 isoform 1 coatomer protein complex, subunit beta 2 1528 0,0031316 0,1120337 832 553,4 1,503 COPB2 (beta prime) developmentall y regulated RNA-binding 2595 0,0078999 0,1664459 110,8 73,7 1,503 DRB1 protein 1 thioredoxin-like 5 /// thioredoxin-like 3365 0,0122036 0,1982671 1534 1020,8 1,503 TXNL5 5

3- hydroxyisobuty ryl-Coenzyme 4366 0,0191682 0,2400415 158,1 105,2 1,503 HIBCH A hydrolase CDNA clone IMAGE:528740 4613 0,0211517 0,2506184 21,5 14,3 1,503 NA 4 methyltransfer 6325 0,0367422 0,3176095 267,9 178,3 1,503 METTL3 ase like 3 chromosome 14 open reading frame 1322 0,0024943 0,1031587 154,4 102,8 1,502 C14orf147 147 RAB22A, member RAS oncogene 3980 0,0161752 0,2222058 134,6 89,6 1,502 RAB22A family

Signal sequence receptor, alpha (translocon- associated 4108 0,0171721 0,2285213 67 44,6 1,502 SSR1 protein alpha) phosphatidylin ositol 4-kinase 5941 0,0326966 0,3009067 861,8 573,9 1,502 PI4KII type II unc-50 homolog (C. 6644 0,0398244 0,3277241 467,7 311,4 1,502 UNC50 elegans) erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) /// erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) /// mitochondrial ribosomal protein S15 /// mitochondrial EPB41 /// ribosomal 1589 0,0033387 0,1148794 169,3 112,8 1,501 MRPS15 protein S15 pyrophosphata se (inorganic) 2955 0,0097429 0,1802684 544,1 362,4 1,501 PPA2 2 chromosome 21 open reading frame 3356 0,0121656 0,1981221 131,8 87,8 1,501 C21orf33 33

chromosome 6 open reading 3637 0,0136612 0,2052986 75,2 50,1 1,501 C6orf162 frame 162

neighbor of BRCA1 gene 1 /// similar to NBR1 /// neighbor of 6522 0,0384749 0,3225222 423,7 282,3 1,501 LOC727732 BRCA1 gene 1 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 319 0,0003214 0,0549787 83,1 55,4 1,5 ATP5G3 (subunit 9) 832 0,0011969 0,0786101 354,5 236,4 1,5 JTV1 JTV1 gene

Small nuclear RNA activating complex, polypeptide 5, 1101 0,0018569 0,0921338 341,8 227,8 1,5 SNAPC5 19kDa hypothetical protein 2738 0,0086292 0,1722103 24,6 16,4 1,5 LOC285550 LOC285550 B double prime 1, subunit of RNA polymerase III transcription initiation factor 2781 0,0088174 0,1733484 132,6 88,4 1,5 BDP1 IIIB serine 3203 0,0113025 0,1929329 689,7 459,9 1,5 SERINC3 incorporator 3

transmembran 3709 0,0141222 0,2080936 9,3 6,2 1,5 TMEM144 e protein 144 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 4097 0,0171057 0,2282778 1988,3 1325,9 1,5 ATP5G3 (subunit 9) 6334 0,0368263 0,3178841 24,6 16,4 1,5 KIAA1958 KIAA1958

transmembran 7022 0,0440818 0,3432316 21,3 14,2 1,5 TMEM142B e protein 142B transmembran e and tetratricopeptid e repeat 7030 0,0441579 0,3433895 8,4 5,6 1,5 TMTC4 containing 4

FK506 binding 7488 0,0490044 0,3578146 256,2 170,8 1,5 FKBP5 protein 5 RNA binding motif protein IL12 0,0022035 0,0980283 221,6 332,8 0,666 RBM25 25 valosin- containing 3233 0,011444 0,1934716 374,5 562,1 0,666 VCP protein

host cell factor C1 regulator 1 (XPO1 6077 0,0341398 0,3071068 111,9 168,1 0,666 HCFC1R1 dependent) RAB11 family interacting protein 1 (class 4136 0,0173423 0,22922 130,5 196,3 0,665 RAB11FIP1 I)

claudin domain 4243 0,0182065 0,2344871 119,8 180,1 0,665 CLDND1 containing 1 acyltransferase 4253 0,0182447 0,2344871 170,7 256,6 0,665 AYTL1 like 1 SH3 domain and tetratricopeptid 1875 0,0043864 0,1278952 94,6 142,5 0,664 SH3TC1 e repeats 1 Ribosomal 2002 0,0048886 0,1334529 102,3 154 0,664 RPS6 protein S6

Growth arrest and DNA- damage- 3745 0,0143178 0,2089303 21,1 31,8 0,664 GADD45B inducible, beta chromodomain helicase DNA binding protein 3914 0,0156633 0,2187531 18,6 28 0,664 CHD3 3 T-cell activation GTPase activating 4773 0,0224178 0,2567972 9,5 14,3 0,664 TAGAP protein F-box and leucine-rich repeat protein 5139 0,0255111 0,2714184 104,5 157,4 0,664 FBXL11 11 testis derived transcript (3 5164 0,0257366 0,2723069 248,7 374,8 0,664 TES LIM domains) Ubiquitin specific 5304 0,0269374 0,2776777 64,9 97,8 0,664 USP36 peptidase 36 hypothetical protein 7111 0,0449676 0,3457465 40,7 61,3 0,664 LOC255783 LOC255783

zinc finger CCCH-type 2558 0,0076365 0,1631875 532,1 802 0,663 ZC3H11A containing 11A 2573 0,0077653 0,1650089 24 36,2 0,663 NA NA serine palmitoyltransf erase, long chain base 2664 0,0082308 0,1688157 137 206,7 0,663 SPTLC2 subunit 2 Full-length cDNA clone CS0DM012YE 14 of Fetal liver of Homo sapiens 3133 0,0108198 0,1888198 6,5 9,8 0,663 NA (human) poliovirus receptor- related 2 (herpesvirus entry mediator 3660 0,0137961 0,2060934 81,3 122,6 0,663 PVRL2 B) 6356 0,0369952 0,3182035 18,3 27,6 0,663 06-sept septin 6 MAP/microtub ule affinity- regulating 842 0,0012172 0,0790355 107,9 162,9 0,662 MARK4 kinase 4 hypothetical protein 2047 0,0051052 0,136359 18,2 27,5 0,662 MGC11082 MGC11082 ERO1-like (S. 2069 0,0051955 0,1372953 613,3 926,4 0,662 ERO1L cerevisiae) mitogen- activated protein kinase 2586 0,0078291 0,1654896 87 131,5 0,662 MAPK1 1 forkhead- associated (FHA) phosphopeptid e binding 4986 0,024175 0,2650734 4,7 7,1 0,662 FHAD1 domain 1 dynein, cytoplasmic 1, light intermediate 5607 0,0296364 0,2889396 259,6 392,3 0,662 DYNC1LI1 chain 1

leucine rich repeat (in FLII) interacting 6205 0,035504 0,3128208 86,7 130,9 0,662 LRRFIP2 protein 2 zinc finger protein 36, C3H type-like 6329 0,0367935 0,3178238 606,2 915,1 0,662 ZFP36L1 1 6633 0,0396792 0,3270707 8,8 13,3 0,662 NA NA H3 histone, family 3B 7110 0,0449669 0,3457465 152,8 230,8 0,662 H3F3B (H3.3B) remodeling and spacing 1373 0,0026387 0,1048471 118,7 179,7 0,661 RSF1 factor 1 SAPS domain family, member 3353 0,0121498 0,1981048 11,9 18 0,661 SAPS2 2 3912 0,0156602 0,2187531 12,1 18,3 0,661 NA NA Trinucleotide repeat 6348 0,036955 0,3181373 8 12,1 0,661 TNRC15 containing 15 dynein, cytoplasmic 1, 6776 0,0414825 0,334719 152,9 231,4 0,661 DYNC1H1 heavy chain 1 matrix metallopeptida 2260 0,0060763 0,1469696 36,1 54,7 0,66 MMP19 se 19 PH domain and leucine rich repeat protein 3974 0,0161375 0,2220226 9,9 15 0,66 PHLPP phosphatase major histocompatibili ty complex, class II, DR beta 6 4590 0,0209235 0,2492097 74,5 112,8 0,66 HLA-DRB6 (pseudogene) methyltransfer 5105 0,0251969 0,2698517 950,9 1440,8 0,66 METTL9 ase like 9 splicing factor, arginine/serine- 5371 0,0275036 0,2799775 839,5 1272,1 0,66 SFRS5 rich 5 kinesin family 6423 0,0375944 0,3199657 22,5 34,1 0,66 KIF13A member 13A T-cell activation NFKB-like 818 0,0011486 0,0767723 17,4 26,4 0,659 TA-NFKBH protein 1403 0,0027228 0,1059917 78,5 119,1 0,659 COIL coilin Zinc finger, FYVE domain 2385 0,0066961 0,1534681 8,9 13,5 0,659 ZFYVE28 containing 28 pinin, desmosome associated 3764 0,0145125 0,2108001 20,5 31,1 0,659 PNN protein

dual-specificity tyrosine-(Y)- phosphorylatio n regulated 6283 0,0363191 0,3160507 324,2 492,2 0,659 DYRK1A kinase 1A S100 calcium binding protein 2513 0,0073763 0,1604852 5215,6 7923,5 0,658 S100A10 A10 mastermind- like 1 3389 0,0123104 0,1984223 139,6 212,1 0,658 MAML1 (Drosophila) chromosome 21 open reading frame 4203 0,0178837 0,2325989 5 7,6 0,658 C21orf71 71 ribonuclease 4672 0,0216229 0,253033 3060,8 4648,5 0,658 RNASET2 T2 bromodomain 5094 0,025109 0,269445 38,9 59,1 0,658 BRD1 containing 1 5703 0,0304976 0,2923823 467,4 709,9 0,658 CCNL1 cyclin L1 6169 0,0351636 0,3116502 40,1 60,9 0,658 NA NA Ras and Rab 6416 0,0375036 0,3195327 43,1 65,5 0,658 RIN1 interactor 1 Solute carrier family 41, 7312 0,0472276 0,3531221 22,3 33,9 0,658 SLC41A2 member 2 Topoisomerase 1353 0,0025638 0,1036037 22,2 33,8 0,657 TOP1 (DNA) I thyroid hormone receptor associated 1711 0,0037337 0,1192668 55,9 85,1 0,657 THRAP2 protein 2 DIX domain 2185 0,0057014 0,1426225 20,9 31,8 0,657 DIXDC1 containing 1

DEAD (Asp- Glu-Ala-Asp) box 2662 0,0082221 0,1688109 13,8 21 0,657 DDX50 polypeptide 50 armadillo repeat containing, X- 3528 0,0130722 0,2025345 19,9 30,3 0,657 ARMCX1 linked 1 LAT1-3TM /// IMAA /// LOC440345 /// LOC440354 /// LOC595101 /// LOC641298 /// LOC728423 /// LOC729513 /// 3769 0,014538 0,2108234 47,3 72 0,657 LOC730099 NA

A kinase (PRKA) anchor 4151 0,0174805 0,2301972 123,7 188,4 0,657 AKAP8 protein 8 solute carrier family 25, 5926 0,032561 0,3003688 21,1 32,1 0,657 SLC25A37 member 37 RAS guanyl releasing protein 2 (calcium and DAG- 7009 0,043891 0,3423622 13,6 20,7 0,657 RASGRP2 regulated) splicing factor, arginine/serine- 595 0,0007206 0,0657513 400 609,7 0,656 SFRS6 rich 6

metallothionein 2037 0,005056 0,1357078 134,1 204,5 0,656 MT1F 1F (functional) Ubiquitin- conjugating enzyme E2H (UBC8 homolog, 2297 0,0062585 0,1489073 10,3 15,7 0,656 UBE2H yeast) heterogeneous nuclear ribonucleoprot 4219 0,0180058 0,2333413 558,4 850,9 0,656 HNRPDL ein D-like glioma tumor suppressor candidate 5198 0,0260411 0,2739125 285,4 435,1 0,656 GLTSCR2 region gene 2 Forkhead box 5347 0,0273345 0,2794089 35,3 53,8 0,656 FOXO3A O3A Kruppel-like 6651 0,039909 0,3280747 282,5 430,8 0,656 KLF13 factor 13 hypothetical protein 585 0,0007061 0,0657513 190,8 291,3 0,655 MGC22014 MGC22014 794 0,001101 0,0757259 7,8 11,9 0,655 OSM oncostatin M 2550 0,0076027 0,1630056 25,2 38,5 0,655 KIAA1546 KIAA1546 zinc finger 4350 0,0190487 0,2394102 41,5 63,4 0,655 ZNF469 protein 469 5115 0,0252537 0,2699248 27,5 42 0,655 NA NA KIAA0232 5137 0,0254938 0,27134 15,4 23,5 0,655 KIAA0232 gene product Transcribed 5292 0,0268209 0,2770916 56,1 85,6 0,655 NA locus CDNA clone IMAGE:384198 299 0,0002923 0,0534498 10,2 15,6 0,654 NA 3 heterogeneous nuclear ribonucleoprot 2826 0,0090599 0,175254 125,7 192,3 0,654 HNRPA0 ein A0

zinc finger CCCH-type 3164 0,0110255 0,1905108 15,1 23,1 0,654 ZC3H11A containing 11A ubiquitin- conjugating enzyme E2B (RAD6 3361 0,0121819 0,1981221 410,9 628,6 0,654 UBE2B homolog)

jumonji domain 3772 0,0145446 0,2108234 78,1 119,5 0,654 JMJD3 containing 3 signal- regulatory 4344 0,0189858 0,2388867 42,8 65,4 0,654 SIRPB1 protein beta 1 4349 0,019047 0,2394102 18,9 28,9 0,654 PANX2 pannexin 2 leucine zipper transcription 4488 0,0201647 0,2456562 29,5 45,1 0,654 LZTFL1 factor-like 1 zinc finger 6827 0,0420003 0,3363594 186,5 285,2 0,654 ZNF267 protein 267 major histocompatibili ty complex, 373 0,0003961 0,0577756 1747,1 2675,2 0,653 HLA-F class I, F

chromosome 7 open reading 3149 0,0109187 0,1895776 63,8 97,7 0,653 C7orf20 frame 20 Josephin domain 3209 0,0113351 0,1931276 183,3 280,8 0,653 JOSD3 containing 3 T-cell activation GTPase activating 4446 0,0197948 0,243428 131,8 201,7 0,653 TAGAP protein 4458 0,0198958 0,2439775 155,9 238,6 0,653 KIAA0737 KIAA0737

transmembran 4465 0,0199414 0,2441497 300,7 460,6 0,653 TMEM149 e protein 149 6431 0,037654 0,3201033 62,8 96,1 0,653 CCNT1 cyclin T1 mediator of RNA polymerase II transcription, subunit 25 homolog (S. cerevisiae) /// meteorin, glial cell differentiation regulator-like /// similar to meteorin, glial MED25 /// cell METRNL /// differentiation 1203 0,002143 0,0973969 405,3 621,2 0,652 LOC653506 regulator-like chromosome 20 open reading frame 1633 0,0034783 0,1161645 7,3 11,2 0,652 C20orf74 74 inositol polyphosphate- 5- phosphatase, 2744 0,0086444 0,1722422 65,7 100,7 0,652 INPP5A 40kDa ubiquitin interaction motif 3436 0,0125598 0,1997647 92,3 141,5 0,652 UIMC1 containing 1 Cdc42 GTPase- activating 3592 0,0134394 0,2043749 105,9 162,3 0,652 CDGAP protein

v-rel reticuloendoth eliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, 4435 0,0197223 0,2431379 187,8 288,1 0,652 RELA p65 (avian) ras homolog gene family, member G (rho 4541 0,0205665 0,2476268 430,2 659,8 0,652 RHOG G) hypothetical protein 5443 0,0281648 0,2828723 11,6 17,8 0,652 LOC283551 LOC283551 casein kinase 425 0,0004529 0,0577884 30,2 46,4 0,651 CSNK1E 1, epsilon development and differentiation enhancing 642 0,0007919 0,067441 1253,9 1926,2 0,651 DDEF1 factor 1 GTP binding 3587 0,0134089 0,2043749 74,2 113,9 0,651 GTPBP1 protein 1 transmembran 5103 0,0251919 0,2698517 8,2 12,6 0,651 TMEM14A e protein 14A 5262 0,0265901 0,2762854 29,3 45 0,651 FKSG44 FKSG44 gene sema domain, transmembran e domain (TM), and cytoplasmic domain, (semaphorin) 5382 0,027596 0,280344 39,4 60,5 0,651 SEMA6B 6B protein tyrosine phosphatase- like A domain 5814 0,0314024 0,2953089 184,3 283,1 0,651 PTPLAD2 containing 2 YY1 associated 6272 0,0362049 0,3155976 370,2 568,5 0,651 YY1AP1 protein 1 ATPase, Class I, type 8B, 782 0,001077 0,0753005 34 52,3 0,65 ATP8B3 member 3 membrane- associated ring finger (C3HC4) 1199 0,0021292 0,0970402 277,7 427,5 0,65 06-mars 6 proline rich 8 PRR8 /// /// similar to LOC727871 proline rich 8 /// /// similar to LOC730348 proline rich 8 /// /// similar to 1565 0,0032635 0,1138946 13 20 0,65 LOC732019 proline rich 8

cylindromatosi s (turban tumor 5908 0,0323955 0,2997838 6,7 10,3 0,65 CYLD syndrome) RNA binding 6246 0,0359411 0,3146141 429,2 660,7 0,65 RBM4 motif protein 4 phosphoprotei n enriched in 811 0,0011325 0,0763495 1176 1813,4 0,649 PEA15 astrocytes 15

hypothetical protein LOC730399 /// LOC730399 hypothetical /// protein 1173 0,0020678 0,0961653 782,3 1205,7 0,649 LOC731974 LOC731974 hypothetical protein 1598 0,0033768 0,115536 31,8 49 0,649 FLJ10154 FLJ10154

Immunoglobuli n superfamily, 2898 0,0093609 0,176607 24,2 37,3 0,649 IGSF2 member 2 family with sequence similarity 105, 3784 0,0146224 0,211279 11,1 17,1 0,649 FAM105B member B inducible T-cell co-stimulator 4281 0,0184633 0,2358049 32,9 50,7 0,649 ICOSLG ligand Bromodomain 5766 0,031032 0,2942489 12,2 18,8 0,649 BRD4 containing 4 hematopoietic SH2 domain 7309 0,0471957 0,3530333 15,9 24,5 0,649 HSH2D containing solute carrier family 11 (proton- coupled divalent metal ion transporters), 1689 0,0036384 0,1177064 27,3 42,1 0,648 SLC11A1 member 1 RNA binding motif protein 1992 0,0048428 0,1329217 170,5 263,3 0,648 RBM33 33 Jumonji domain 2197 0,0057637 0,1434366 7 10,8 0,648 JMJD2B containing 2B

cytochrome P450, family 1, subfamily A, 5012 0,0244187 0,2663792 12,9 19,9 0,648 CYP1A1 polypeptide 1 transducin (beta)-like 1X- 5755 0,0309558 0,2940935 41,8 64,5 0,648 TBL1X linked

vitamin D (1,25- dihydroxyvitam 2436 0,006947 0,1557913 33,2 51,3 0,647 VDR in D3) receptor

ring finger and KH domain 3422 0,012429 0,1985434 13 20,1 0,647 RKHD2 containing 2

SMAD specific E3 ubiquitin 3615 0,0135328 0,2046766 152,9 236,4 0,647 SMURF2 protein ligase 2 cytidine and dCMP deaminase domain 5076 0,0249796 0,2690622 13,2 20,4 0,647 CDADC1 containing 1 chromosome 10 open reading frame 137 /// chromosome 10 open reading frame 5981 0,0331824 0,3033352 12,1 18,7 0,647 C10orf137 137 6140 0,0348526 0,3103528 88,9 137,5 0,647 NA NA thyroid hormone receptor associated 1151 0,0019995 0,0949806 45,2 70 0,646 THRAP2 protein 2 Phosphodieste rase 4B, cAMP- specific (phosphodiest erase E4 dunce homolog, 1498 0,0030222 0,1103063 5,3 8,2 0,646 PDE4B Drosophila) solute carrier family 25, member 28 /// solute carrier family 25, 2114 0,0053855 0,1392868 66,9 103,5 0,646 SLC25A28 member 28 interleukin 13 receptor, alpha 2974 0,009847 0,1810305 217,4 336,6 0,646 IL13RA1 1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid 3006 0,0100412 0,1826356 570,2 882,3 0,646 NR3C1 receptor)

jumonji domain 5662 0,0301475 0,2910113 290,4 449,8 0,646 JMJD2B containing 2B

chromosome X open reading 6916 0,0428528 0,3387763 6,4 9,9 0,646 CXorf6 frame 6 angiopoietin- 1858 0,0042881 0,1261495 14,9 23,1 0,645 ANGPTL4 like 4 nuclear autoantigenic sperm protein (histone- 2255 0,0060507 0,146706 110,8 171,8 0,645 NASP binding) headcase homolog 3251 0,011519 0,1936505 291,6 451,9 0,645 HECA (Drosophila) CDNA FLJ12853 fis, clone NT2RP200345 1937 0,0045975 0,129772 84,7 131,5 0,644 NA 6 single- stranded DNA binding protein 3463 0,0126704 0,2000445 29,1 45,2 0,644 SSBP2 2 hypothetical protein 4917 0,0235721 0,2621054 26,1 40,5 0,644 MGC13114 MGC13114

far upstream element (FUSE) binding 5366 0,0274658 0,2798111 102,7 159,4 0,644 FUBP1 protein 1 forkhead box 5717 0,0306099 0,2927403 128,4 199,4 0,644 FOXP1 P1

sema domain, immunoglobuli n domain (Ig), transmembran e domain (TM) and short cytoplasmic domain, (semaphorin) 6950 0,0432973 0,3406158 26 40,4 0,644 SEMA4B 4B similar to RIKEN cDNA 1432 0,0028101 0,1071379 35,9 55,8 0,643 LOC440104 1110012D08 calmodulin binding transcription 4746 0,0221763 0,2554021 5,4 8,4 0,643 CAMTA1 activator 1 solute carrier family 19 (thiamine transporter), 6392 0,0372343 0,3184896 43,1 67 0,643 SLC19A2 member 2 serine palmitoyltransf erase, long chain base 6657 0,0400387 0,328761 10,1 15,7 0,643 SPTLC2 subunit 2 sema domain, transmembran e domain (TM), and cytoplasmic domain, (semaphorin) 6880 0,0423913 0,3368814 56,8 88,3 0,643 SEMA6B 6B thioredoxin-like 6952 0,0433317 0,3407884 32,9 51,2 0,643 TXNL4B 4B

tumor necrosis factor receptor superfamily, member 19- 1386 0,002669 0,1051826 102,9 160,3 0,642 TNFRSF19L like myeloid/lymph oid or mixed- lineage 1861 0,0042977 0,1262637 59,8 93,2 0,642 MLL3 leukemia 3 MOB1, Mps One Binder kinase activator-like 2686 0,0083286 0,169519 157,5 245,4 0,642 MOBKL2A 2A (yeast) solute carrier family 25, 3262 0,011559 0,1936505 7 10,9 0,642 SLC25A37 member 37 nuclear factor (erythroid- derived 2)-like 3968 0,0160649 0,221358 1242,5 1936,3 0,642 NFE2L2 2 hypothetical protein FLJ22639 /// hypothetical FLJ22639 /// protein 4067 0,0168613 0,2266761 7 10,9 0,642 LOC728686 LOC728686 zinc finger 4567 0,020742 0,2482781 7,7 12 0,642 ZNF326 protein 326 5163 0,0257336 0,2723069 6,1 9,5 0,642 KIAA1509 KIAA1509 MAX dimerization 1703 0,0036966 0,1186797 55,1 86 0,641 MXD4 protein 4

aspartate beta- hydroxylase domain 2894 0,009348 0,1766012 44,9 70,1 0,641 ASPHD2 containing 2 chromosome 10 open reading frame 6206 0,0355119 0,3128208 16,6 25,9 0,641 C10orf78 78 family with sequence similarity 53, 6374 0,0371022 0,3182128 174,1 271,5 0,641 FAM53C member C

Zinc finger, CCHC domain 7125 0,0451143 0,3461926 69,2 108 0,641 ZCCHC6 containing 6 CCR4-NOT transcription complex, 767 0,0010537 0,0751122 207,3 323,9 0,64 CNOT2 subunit 2 chromosome 21 open reading frame 1029 0,0016606 0,0879972 45,9 71,7 0,64 C21orf66 66 proline rich Gla (G- carboxyglutami c acid) 4 (transmembran 2345 0,0064741 0,1509473 55,6 86,9 0,64 PRRG4 e) Hypothetical gene supported by 2882 0,0093096 0,1765671 32,5 50,8 0,64 LOC440944 AK128398

leucine rich repeat (in FLII) interacting 918 0,0013636 0,0812144 568,9 889,9 0,639 LRRFIP1 protein 1

cytochrome P450, family 1, subfamily B, 3960 0,0160034 0,220943 2275,2 3559,9 0,639 CYP1B1 polypeptide 1 splicing factor 3a, subunit 2, 5027 0,0245485 0,2669883 26,6 41,6 0,639 SF3A2 66kDa ubiquitin- conjugating enzyme E2, J2 (UBC6 homolog, 5074 0,0249389 0,2687297 215,4 337,2 0,639 UBE2J2 yeast)

tyrosine 3- monooxygenas e/tryptophan 5- monooxygenas e activation protein, eta 6761 0,0413284 0,3341999 202,6 316,9 0,639 YWHAH polypeptide PI-3-kinase- related kinase 7082 0,044633 0,3445667 27,6 43,2 0,639 SMG1 SMG-1

NBPF1 /// NBPF3 /// KIAA1245 /// NBPF11 /// NBPF20 /// NBPF9 /// NBPF10 /// NBPF8 /// LOC728895 /// 7118 0,0450548 0,3460577 79,5 124,5 0,639 LOC728912 NA Ubiquitin- conjugating enzyme E2D 2 (UBC4/5 homolog, 7479 0,0489481 0,3577665 20 31,3 0,639 UBE2D2 yeast)

methyl-CpG binding domain 6250 0,0359762 0,3147198 1024,3 1604,5 0,638 MBD4 protein 4 Lipase, hormone- 1104 0,0018624 0,0922251 80,3 126 0,637 LIPE sensitive

calmodulin regulated spectrin- CAMSAP1L associated 1796 0,0040537 0,1233958 85,8 134,6 0,637 1 protein 1-like 1 KIAA0286 1165 0,0020332 0,0954208 54,8 86,1 0,636 KIAA0286 protein

Vacuolar protein sorting 37 homolog B 5013 0,0244355 0,2665093 14 22 0,636 VPS37B (S. cerevisiae) SCAN domain 5472 0,0284526 0,2842101 19,6 30,8 0,636 SCAND1 containing 1 Signal- regulatory 6216 0,0356228 0,3133328 128,1 201,3 0,636 SIRPA protein alpha RNA binding motif protein 6507 0,0383453 0,322196 317,7 499,5 0,636 RBM15 15 chromosome 20 open reading frame 6714 0,0406934 0,3313561 22,5 35,4 0,636 C20orf67 67

solute carrier family 39 (zinc transporter), 6767 0,0413767 0,3342663 69,2 108,8 0,636 SLC39A4 member 4 zinc finger 617 0,0007437 0,0657513 7,3 11,5 0,635 ZNF569 protein 569 Centaurin, 1963 0,0046973 0,1308328 13,4 21,1 0,635 CENTG3 gamma 3 calmin (calponin-like, transmembran 2777 0,0088011 0,1732398 42 66,1 0,635 CLMN e) CDC42 small 4800 0,0226445 0,257834 6,6 10,4 0,635 CDC42SE2 effector 2 4828 0,0228403 0,2586565 498,8 785,1 0,635 KIAA1949 KIAA1949 coiled-coil domain 821 0,0011586 0,0771577 56,2 88,7 0,634 CCDC23 containing 23 similar to RIKEN cDNA B230118G17 852 0,0012377 0,0791194 52,2 82,3 0,634 MGC19604 gene C-type lectin domain family 1384 0,0026637 0,1051826 572,4 902,3 0,634 CLEC7A 7, member A misshapen-like kinase 1 5440 0,0281561 0,2828723 33,4 52,7 0,634 MINK1 (zebrafish) M-phase phosphoprotei 5475 0,0284624 0,2842341 10,2 16,1 0,634 MPHOSPH6 n 6 ariadne homolog, ubiquitin- conjugating enzyme E2 binding protein, 1 5484 0,0285431 0,2845722 156,7 247,1 0,634 ARIH1 (Drosophila) interferon induced transmembran e protein 3 (1- 7316 0,0472622 0,3532068 103,3 162,9 0,634 IFITM3 8U) chromosome 16 open reading frame 3005 0,0100383 0,1826356 20,5 32,4 0,633 C16orf74 74 Serine palmitoyltransf erase, long chain base 4965 0,0239484 0,2637218 13,8 21,8 0,633 SPTLC2 subunit 2 RB1-inducible 5235 0,0263728 0,2754408 100,1 158,2 0,633 RB1CC1 coiled-coil 1

6689 0,0404197 0,3303853 121,6 192 0,633 CGI-09 CGI-09 protein Full-length cDNA clone CS0DN005YM 11 of Adult brain of Homo sapiens 591 0,0007154 0,0657513 27,7 43,8 0,632 NA (human) ash1 (absent, small, or homeotic)-like 976 0,0015094 0,0845558 184,2 291,5 0,632 ASH1L (Drosophila) 1084 0,0018017 0,0908008 402,1 636,4 0,632 UBN1 ubinuclein 1 heterogeneous nuclear ribonucleoprot 1652 0,0035099 0,1161645 437,9 693,4 0,632 HNRPA1 ein A1 diacylglycerol kinase, alpha 6229 0,035803 0,3142364 12,9 20,4 0,632 DGKA 80kDa BCL6 co- 6680 0,0403447 0,3302165 7,9 12,5 0,632 BCOR repressor

cytokine induced 7462 0,0487298 0,3570493 48,8 77,2 0,632 CIP29 protein 29 kDa Calcium binding protein 7491 0,0490376 0,3578906 50,8 80,4 0,632 CABP4 4

solute carrier family 22 (organic cation transporter), 1733 0,0038042 0,1199919 53,6 85 0,631 SLC22A4 member 4 chromosome 10 open reading frame 2233 0,0059187 0,1449194 34 53,9 0,631 C10orf47 47 lin-7 homolog 5547 0,0291188 0,2868871 10,6 16,8 0,631 LIN7A A (C. elegans) ribosomal 900 0,0013206 0,0802264 98,8 156,8 0,63 RPL31 protein L31 EPH receptor 2486 0,0072476 0,1593976 35,6 56,5 0,63 EPHB2 B2 RAB2, member RAS oncogene 2546 0,0075906 0,1628925 56,6 89,8 0,63 RAB2 family small Cajal body-specific 2580 0,0077995 0,1652859 25,9 41,1 0,63 SCARNA17 RNA 17 SH3-domain 3136 0,0108431 0,1889066 153,9 244,2 0,63 SH3GL1 GRB2-like 1 F-box and WD- 40 domain protein 7 (archipelago homolog, 3165 0,0110282 0,1905108 79,8 126,6 0,63 FBXW7 Drosophila) sex comb on midleg-like 1 5671 0,0302249 0,291403 112,9 179,1 0,63 SCML1 (Drosophila)

CDNA FLJ40174 fis, clone 258 0,0002467 0,0521767 8,8 14 0,629 NA TESTI2016996 WAS protein family, member 3819 0,014921 0,2136176 107,8 171,4 0,629 WASF2 2

GRP1 (general receptor for phosphoinositi des 1)- associated 4956 0,0238738 0,2633777 28,8 45,8 0,629 GRASP scaffold protein mucosa associated lymphoid tissue lymphoma translocation 5468 0,0284123 0,284097 106 168,4 0,629 MALT1 gene 1 Shwachman- Bodian- Diamond 1860 0,0042941 0,1262258 213,4 339,7 0,628 SBDS syndrome son of sevenless homolog 2 1908 0,0045062 0,1291281 21,3 33,9 0,628 SOS2 (Drosophila) plasminogen activator, 2802 0,0089766 0,1750515 5,9 9,4 0,628 PLAT tissue PHD finger 3232 0,0114433 0,1934716 43,8 69,8 0,628 PHF21A protein 21A Chromodomai n helicase DNA binding protein 3287 0,0117273 0,1950441 816 1299,9 0,628 CHD2 2 v-maf musculoapone urotic fibrosarcoma oncogene homolog G (avian) /// similar to v-maf musculoapone urotic fibrosarcoma oncogene MAFG /// family, protein 3807 0,0148522 0,2133029 110,4 176 0,627 LOC644132 G high-mobility group protein 2- 4299 0,0186319 0,2368636 189 301,5 0,627 HMG2L1 like 1 Multiple Gene 4507 0,0202944 0,2460654 37,7 60,1 0,627 Symbols NA Hypothetical 6071 0,0340563 0,3067086 31,9 50,9 0,627 LOC550112 LOC550112 histone cluster 7098 0,0447828 0,3449563 27,6 44 0,627 HIST1H1C 1, H1c ral guanine nucleotide dissociation 7528 0,049488 0,3593977 93,1 148,4 0,627 RALGDS stimulator PR domain containing 2, with ZNF 529 0,0006187 0,0635709 150,9 241,2 0,626 PRDM2 domain weakly similar to serine/threonin e protein 1655 0,0035288 0,1165783 12,4 19,8 0,626 LOC442075 kinase Kp78 zuotin related 1812 0,0041206 0,1241646 261 417,4 0,625 ZRF1 factor 1

A kinase (PRKA) anchor 2683 0,0083122 0,1693886 7,5 12 0,625 AKAP13 protein 13

chromosome 17 open reading frame 49 /// similar to DNA segment, Chr 11, Brigham & Womens C17orf49 /// Genetics 0434 3721 0,0141774 0,2083175 112,1 179,3 0,625 MGC71993 expressed unc-51-like kinase 1 (C. 3891 0,0155145 0,2180044 34,9 55,8 0,625 ULK1 elegans) zinc finger, 4282 0,0184794 0,2359554 87,6 140,2 0,625 ZMYM2 MYM-type 2 hairy and enhancer of split 4 5477 0,0284867 0,284323 11 17,6 0,625 HES4 (Drosophila)

Homo sapiens, clone IMAGE:40823 6011 0,0334772 0,3044442 102,8 164,6 0,625 NA 61, mRNA anthrax toxin 1241 0,002234 0,0984238 54,7 87,6 0,624 ANTXR2 receptor 2 solute carrier family 29 (nucleoside transporters), 1871 0,0043713 0,1277396 31,4 50,3 0,624 SLC29A1 member 1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 1879 0,004397 0,1279192 16,9 27,1 0,624 NFKB2 (p49/p100) 2770 0,0087842 0,1732398 361,6 579,3 0,624 CCNK cyclin K RAS-related on chromosome 4269 0,01834 0,2348886 16,6 26,6 0,624 RRP22 22 CDNA clone IMAGE:526243 5674 0,0303038 0,2916051 7,3 11,7 0,624 NA 8 glioma tumor suppressor candidate 2680 0,0083032 0,1693865 3089,1 4959,3 0,623 GLTSCR2 region gene 2 YY1 transcription 2797 0,0089499 0,1748897 37,8 60,7 0,623 YY1 factor karyopherin alpha 4 (importin alpha 6558 0,0388434 0,3238431 348,3 559,2 0,623 KPNA4 3) CASP8 and FADD-like apoptosis 6802 0,0417518 0,3355958 312,5 502 0,623 CFLAR regulator

jumonji, AT rich interactive 7109 0,0449629 0,3457465 182 292,1 0,623 JARID2 domain 2 CDC42 small 7384 0,0479563 0,3550265 80,4 129,1 0,623 CDC42SE2 effector 2

641 0,0007886 0,0672648 5,6 9 0,622 SYNJ2 Synaptojanin 2 Cas-Br-M (murine) ecotropic retroviral transforming 2753 0,0086946 0,1726761 131,4 211,1 0,622 CBLB sequence b CKLF-like MARVEL transmembran e domain 6786 0,0415893 0,3350862 6,1 9,8 0,622 CMTM2 containing 2 609 0,000735 0,0657513 838,9 1350,9 0,621 NA NA polycomb group ring 1880 0,0044014 0,1279192 16,2 26,1 0,621 PCGF2 finger 2 Transcribed 1920 0,0045453 0,1293549 48,4 78 0,621 NA locus

chloride intracellular channel 3 /// rabaptin, RAB GTPase CLIC3 /// binding effector 3569 0,0133141 0,203925 6,4 10,3 0,621 RABEP1 protein 1 1676 0,003613 0,1177064 15,8 25,5 0,62 FLOT1 flotillin 1 FYVE, RhoGEF and PH domain 2387 0,0067043 0,1535641 186,4 300,6 0,62 FGD3 containing 3 Transcribed 4950 0,0238253 0,2631613 11,4 18,4 0,62 NA locus

guanylate binding protein 2, interferon- inducible /// guanylate binding protein 2, interferon- 5276 0,0267011 0,2766543 298,7 481,5 0,62 GBP2 inducible Fragile X mental retardation, autosomal 7236 0,0463767 0,350421 12,4 20 0,62 FXR2 homolog 2 SLC7A5 752 0,0010098 0,0732456 23,6 38,1 0,619 IMAA pseudogene discs, large (Drosophila) homolog- associated 1310 0,0024691 0,1029968 67,4 108,9 0,619 DLGAP4 protein 4 Topoisomerase 1316 0,0024847 0,1029968 31,2 50,4 0,619 TOP1 (DNA) I

tumor necrosis factor (ligand) superfamily, member 10 /// tumor necrosis factor (ligand) superfamily, 1483 0,0029755 0,1095772 7 11,3 0,619 TNFSF10 member 10 U2 small nuclear RNA auxiliary factor 1657 0,0035399 0,1168039 816,7 1320,2 0,619 U2AF1 1 chromosome 10 open reading frame 3068 0,0104681 0,1863882 5,2 8,4 0,619 C10orf47 47 CDNA FLJ30010 fis, clone 3NB69200015 3771 0,0145429 0,2108234 50,3 81,2 0,619 NA 4 TGFB-induced factor (TALE family 4531 0,0204794 0,2471223 143,4 231,5 0,619 TGIF homeobox) major histocompatibili ty complex, 279 0,0002694 0,0525339 1357,7 2197,7 0,618 HLA-F class I, F

nuclear factor of kappa light polypeptide gene enhancer in B-cells 4596 0,0209709 0,2493908 25,9 41,9 0,618 NFKBIB inhibitor, beta secreted phosphoprotei n 1 (osteopontin, bone sialoprotein I, early T- lymphocyte 5291 0,0268133 0,2770775 4031,6 6521,9 0,618 SPP1 activation 1)

pituitary tumor- 5505 0,028798 0,2860183 82,1 132,9 0,618 PTTG1 transforming 1 Sterol regulatory element binding transcription 5843 0,0316995 0,2966233 46,2 74,8 0,618 SREBF2 factor 2

vitamin D (1,25- dihydroxyvitam 5912 0,0324319 0,2999154 216,5 350,2 0,618 VDR in D3) receptor metastasis associated lung adenocarcino ma transcript 1 (non-coding 2124 0,0054434 0,1401018 518,8 840,5 0,617 MALAT1 RNA) EPH receptor 3074 0,0105141 0,1869867 19,3 31,3 0,617 EPHB2 B2 MRNA; cDNA DKFZp667C03 1 (from clone DKFZp667C03 3792 0,0147417 0,2125534 9,5 15,4 0,617 NA 1)

WD repeat and FYVE domain 5301 0,0269135 0,2775883 12,1 19,6 0,617 WDFY1 containing 1 poly (ADP- ribose) polymerase family, member 5704 0,0305043 0,2923929 33,4 54,1 0,617 PARP9 9 kelch-like 24 2419 0,0068823 0,1555358 103 167,2 0,616 KLHL24 (Drosophila) GC-rich promoter binding protein 3870 0,015394 0,2174619 393 637,6 0,616 GPBP1 1

zinc finger and BTB domain 4889 0,0233617 0,261228 14,3 23,2 0,616 ZBTB10 containing 10

2799 0,0089548 0,1749209 5,9 9,6 0,615 CD47 CD47 molecule eukaryotic translation initiation factor 5258 0,0265497 0,2760755 93,3 151,7 0,615 EIF5 5 LIM and senescent cell antigen-like 5626 0,0297959 0,2894775 28 45,5 0,615 LIMS3 domains 3 CCR4-NOT transcription complex, 6389 0,0372192 0,318471 10,7 17,4 0,615 CNOT4 subunit 4

Activity- dependent 6833 0,0420622 0,3365393 41,7 67,8 0,615 ADNP neuroprotector Hypothetical gene supported by 637 0,0007805 0,0669919 30,1 49 0,614 LOC440944 AK128398

nurim (nuclear envelope membrane 1585 0,0033211 0,1145622 117,7 191,7 0,614 NRM protein) F-box and leucine-rich repeat protein 2238 0,0059626 0,1456681 126,4 205,7 0,614 FBXL11 11

hexamethylene bis-acetamide 5367 0,0274686 0,2798111 70,7 115,1 0,614 HEXIM1 inducible 1 vesicle- associated membrane protein 1 (synaptobrevin 6318 0,0366965 0,3175527 41,6 67,8 0,614 VAMP1 1) forkhead box 6692 0,0404501 0,3304855 170,3 277,4 0,614 FOXP1 P1 Ariadne homolog, ubiquitin- conjugating enzyme E2 binding protein, 1 7031 0,0441586 0,3433895 11,3 18,4 0,614 ARIH1 (Drosophila) Kruppel-like 7252 0,0465525 0,350949 61,3 99,8 0,614 KLF13 factor 13 pleckstrin homology domain containing, family G (with RhoGef domain) 367 0,0003872 0,0575573 24,9 40,6 0,613 PLEKHG2 member 2 Shwachman- Bodian- Diamond syndrome /// Shwachman- Bodian- Diamond SBDS /// syndrome 1948 0,004634 0,1300636 208,4 339,8 0,613 SBDSP pseudogene Kruppel-like 3204 0,0113096 0,1929939 10 16,3 0,613 KLF11 factor 11 3205 0,0113213 0,1931122 153,6 250,4 0,613 NA NA methyltransfer 4455 0,0198768 0,2439425 57,4 93,6 0,613 METTL9 ase like 9 Family with sequence similarity 80, 4912 0,0235341 0,2619125 6,5 10,6 0,613 FAM80B member B phosphatidylin ositol-3- phosphate/pho sphatidylinosito l 5-kinase, type 1235 0,0022167 0,0980838 25,7 42 0,612 PIP5K3 III

DnaJ (Hsp40) homolog, subfamily C, 6408 0,0373534 0,3187105 71,9 117,5 0,612 DNAJC5B member 5 beta

neutrophil cytosolic factor 4, 40kDa /// neutrophil cytosolic factor 3289 0,0117356 0,1950568 134,8 220,7 0,611 NCF4 4, 40kDa proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional 4997 0,0242578 0,2654183 455,3 745,1 0,611 PSMB9 peptidase 2) carbohydrate (chondroitin) 6049 0,0338578 0,3060039 304,8 499,2 0,611 CHSY1 synthase 1

Heterogeneou s nuclear ribonucleoprot ein D (AU-rich element RNA binding protein 6343 0,0369136 0,3181373 58,5 95,8 0,611 HNRPD 1, 37kDa) calmin (calponin-like, transmembran 6357 0,0370121 0,3182035 20,9 34,2 0,611 CLMN e) Microsomal glutathione S- 885 0,001289 0,079454 67,7 110,9 0,61 MGST1 transferase 1

influenza virus NS1A binding 3979 0,0161698 0,2221874 8,6 14,1 0,61 IVNS1ABP protein pleckstrin homology, Sec7 and coiled-coil domains 4019 0,0165217 0,2247156 180,9 296,4 0,61 PSCD1 1(cytohesin 1) kelch repeat and BTB (POZ) domain 4343 0,0189828 0,2388867 152,3 249,7 0,61 KBTBD2 containing 2

Solute carrier family 1 (glutamate/neu tral amino acid transporter), 5386 0,0276505 0,2806264 24,6 40,3 0,61 SLC1A4 member 4 transporter 1, ATP-binding cassette, sub- family B 6938 0,0431675 0,3401677 209,2 343,1 0,61 TAP1 (MDR/TAP) similar to splicing factor, arginine/serine- 1813 0,0041246 0,1241646 494,5 812,4 0,609 FLJ11021 rich 4 ubiquitin- conjugating enzyme E2B (RAD6 1883 0,0044077 0,1279192 523,5 859,7 0,609 UBE2B homolog) Eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange 2261 0,0060777 0,1469696 16,8 27,6 0,609 EEF1D protein) receptor- interacting serine- threonine 4548 0,0206155 0,2476563 424 696,2 0,609 RIPK2 kinase 2 1356 0,0025784 0,1039631 612,7 1008,4 0,608 NA NA cytoplasmic polyadenylatio n element binding protein 1825 0,004152 0,1242557 160,9 264,8 0,608 CPEB2 2 stromal membrane- associated 2062 0,0051615 0,1368599 243,1 399,7 0,608 SMAP1L protein 1-like topoisomerase I binding, arginine/serine- 2307 0,0063213 0,149757 100,8 165,8 0,608 TOPORS rich serine/threonin RP6- e protein 2997 0,0100128 0,1825536 117,8 193,8 0,608 213H19.1 kinase MST4 calmin (calponin-like, transmembran 4283 0,0184876 0,236005 50,7 83,4 0,608 CLMN e) tetratricopeptid e repeat 4555 0,0206563 0,2479436 157,9 259,6 0,608 TTC32 domain 32 ADP- ribosylation 5268 0,0266561 0,276654 510,8 840,2 0,608 ARF6 factor 6 nucleoporin 953 0,0014493 0,0831485 152,6 251,5 0,607 NUP214 214kDa hypothetical protein 2673 0,0082651 0,1690181 38,5 63,4 0,607 FLJ21438 FLJ21438 ATPase, H+ transporting, lysosomal 50/57kDa, V1 3038 0,0102367 0,1842303 25,9 42,7 0,607 ATP6V1H subunit H family with sequence similarity 100, 1420 0,0027724 0,1067259 31,4 51,8 0,606 FAM100B member B 1653 0,0035212 0,116468 41 67,7 0,606 KIAA2026 KIAA2026 phosphomann 2531 0,0074765 0,1615084 25,7 42,4 0,606 PMM1 omutase 1

chromosome 6 open reading 5747 0,0309116 0,2939651 42,3 69,8 0,606 C6orf151 frame 151 Tight junction associated protein 1 5849 0,0317636 0,296902 13,2 21,8 0,606 TJAP1 (peripheral) coagulation factor C homolog, cochlin (Limulus 6381 0,0371491 0,3182155 287,4 474,5 0,606 COCH polyphemus) zinc finger, AN1-type 644 0,0007988 0,0678174 73,7 121,9 0,605 ZFAND3 domain 3

YME1-like 1 3338 0,0120399 0,1971755 115,9 191,7 0,605 YME1L1 (S. cerevisiae) THAP domain 4393 0,019453 0,2421108 108,5 179,3 0,605 THAP11 containing 11 Exostoses 5093 0,025107 0,269445 6,9 11,4 0,605 EXT1 (multiple) 1 6985 0,0436943 0,341888 54,6 90,2 0,605 FMNL1 formin-like 1 939 0,0014182 0,082425 1825,9 3022,3 0,604 NA NA

tumor necrosis factor (ligand) superfamily, 2716 0,0084715 0,1705373 34,2 56,6 0,604 TNFSF8 member 8

runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 2910 0,0094548 0,177643 22,7 37,6 0,604 RUNX1 oncogene) pim-2 5097 0,0251232 0,269494 38,4 63,6 0,604 PIM2 oncogene hydroxysteroid (17-beta) dehydrogenas 130 0,0001028 0,0431325 46 76,3 0,603 HSD17B8 e 8 forkhead box 1240 0,0022323 0,0984238 46,8 77,6 0,603 FOXO3A O3A interleukin 6 signal transducer (gp130, oncostatin M 2600 0,0079318 0,1666005 4,7 7,8 0,603 IL6ST receptor) ubiquitin specific 4640 0,0213529 0,251578 564,5 935,7 0,603 USP3 peptidase 3

diacylglycerol kinase, alpha 80kDa /// beta- DGKA /// carotene 6822 0,0419156 0,3358999 41,9 69,5 0,603 BCDO2 dioxygenase 2 Transcribed 7276 0,0468688 0,3520266 4,4 7,3 0,603 NA locus spermine 6788 0,0416361 0,3353583 162 268,9 0,602 SMOX oxidase 7496 0,0490817 0,3579965 20,9 34,7 0,602 MSN Moesin RAS, dexamethason 895 0,0013104 0,0800515 19,4 32,3 0,601 RASD1 e-induced 1 mucosa associated lymphoid tissue lymphoma translocation 3415 0,0123982 0,1984223 139,3 231,9 0,601 MALT1 gene 1 Metastasis 5165 0,0257385 0,2723069 10,7 17,8 0,601 MTSS1 suppressor 1

ribosomal protein S6 kinase, 90kDa, 6388 0,0371864 0,318279 25,6 42,6 0,601 RPS6KA5 polypeptide 5 solute carrier family 25, 2223 0,005862 0,1441488 25,4 42,3 0,6 SLC25A34 member 34 Calpain, small 3393 0,0123287 0,1984223 9,9 16,5 0,6 CAPNS2 subunit 2 WW domain containing adaptor with 4274 0,018381 0,2351383 7,2 12 0,6 WAC coiled-coil major histocompatibili ty complex, class II, DP 5491 0,0286117 0,2848925 3621,4 6033,8 0,6 HLA-DPA1 alpha 1 Multiple Gene 1071 0,0017701 0,0903205 404,2 675,1 0,599 Symbols NA high-mobility 2975 0,009858 0,181122 34,1 56,9 0,599 HMGB3 group box 3 toll-like receptor adaptor 5668 0,0301683 0,2910113 154,5 258,1 0,599 TICAM2 molecule 2 5744 0,0308776 0,2939124 689,7 1150,5 0,599 NA NA LATS, large tumor suppressor, homolog 2 6943 0,0432429 0,3404595 9,1 15,2 0,599 LATS2 (Drosophila) Transcribed 7015 0,0439608 0,342631 8,2 13,7 0,599 NA locus tripeptidyl 3703 0,0140769 0,2078462 12,2 20,4 0,598 TPP2 peptidase II Ubiquitin- conjugating enzyme E2H (UBC8 homolog, 4991 0,0242184 0,2652969 23,2 38,8 0,598 UBE2H yeast) HMG-box transcription 1400 0,0027167 0,1059917 372,3 624 0,597 HBP1 factor 1 mucosa associated lymphoid tissue lymphoma translocation 2726 0,008525 0,1709847 127,4 213,4 0,597 MALT1 gene 1

neutrophil cytosolic factor 2906 0,0094404 0,1776166 131,8 220,6 0,597 NCF4 4, 40kDa

F-box and WD- 40 domain protein 7 (archipelago homolog, 3705 0,0140914 0,2079258 51,2 85,7 0,597 FBXW7 Drosophila)

Guanine nucleotide binding protein (G protein) 5811 0,0313738 0,2951923 13,9 23,3 0,597 GNA12 alpha 12 Adenosine monophosphat e deaminase 544 0,0006341 0,0635709 19,9 33,4 0,596 AMPD3 (isoform E)

platelet- activating factor receptor /// platelet- activating 1716 0,0037445 0,1193068 393,2 659,3 0,596 PTAFR factor receptor N-acetylated alpha-linked acidic dipeptidase- 1822 0,0041483 0,1242557 9,6 16,1 0,596 NAALADL1 like 1 discs, large (Drosophila) homolog- associated 2141 0,0055105 0,1407224 15,8 26,5 0,596 DLGAP4 protein 4 adaptor-related protein complex 1, sigma 2 subunit /// similar to adaptor-related protein complex 1 sigma 2 subunit /// similar to adaptor-related AP1S2 /// protein LOC653653 complex 1 /// sigma 2 2366 0,0066062 0,1526602 142,2 238,5 0,596 LOC654127 subunit topoisomerase (DNA) I, 2678 0,0082964 0,1693496 53,5 89,7 0,596 TOP1MT mitochondrial AF4/FMR2 family, member 4660 0,021493 0,2521738 32,7 54,9 0,596 AFF4 4 period homolog 1 5438 0,0281315 0,2828411 70,2 117,8 0,596 PER1 (Drosophila) Josephin domain 1735 0,0038077 0,1199919 314,3 528,3 0,595 JOSD1 containing 1

ATPase, Class 2416 0,0068672 0,1553951 12,2 20,5 0,595 ATP11B VI, type 11B eukaryotic translation initiation factor 3170 0,0111077 0,1915815 185,1 310,9 0,595 EIF2C2 2C, 2

SP100 nuclear 3612 0,0135023 0,2043768 143,1 240,6 0,595 SP100 antigen chromosome 20 open reading frame 4107 0,0171721 0,2285213 44,2 74,3 0,595 C20orf112 112

protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha 4513 0,0203172 0,2461429 234,3 394 0,595 PPP2R2A isoform

Zinc finger and BTB domain 5168 0,0257543 0,2723069 10 16,8 0,595 ZBTB10 containing 10 raftlin, lipid raft 5270 0,0266746 0,276654 256,6 431,6 0,595 RFTN1 linker 1 vesicle- associated membrane protein 5 5756 0,0309751 0,2941686 67,4 113,2 0,595 VAMP5 (myobrevin) FOS-like 2647 0,0081332 0,167995 38,1 64,1 0,594 FOSL2 antigen 2 7393 0,0480476 0,355236 155,8 262,2 0,594 NA NA membrane- associated ring finger (C3HC4) 769 0,0010605 0,075254 27,8 46,9 0,593 09-mars 9

chromosome 4 open reading 2014 0,0049447 0,1341912 24,6 41,5 0,593 C4orf30 frame 30 Tau tubulin 6306 0,0365885 0,3172173 11,5 19,4 0,593 TTBK2 kinase 2 tumor protein 6497 0,0383067 0,322196 16,9 28,5 0,593 TPD52 D52

CDC42 effector protein (Rho GTPase 6800 0,0417395 0,3355924 45,4 76,5 0,593 CDC42EP4 binding) 4 coiled-coil domain 419 0,0004472 0,0577884 47,7 80,6 0,592 CCDC45 containing 45 X-prolyl aminopeptidas e (aminopeptida se P) 2, membrane- 1512 0,0030713 0,1110329 22,8 38,5 0,592 XPNPEP2 bound

jumonji, AT rich interactive 2248 0,006019 0,1463492 338,3 571,2 0,592 JARID2 domain 2 myeloid/lymph oid or mixed- lineage leukemia 5 (trithorax homolog, 3694 0,0140155 0,2073717 306,2 517,3 0,592 MLL5 Drosophila)

Ankyrin repeat 4706 0,0218727 0,2541069 47,5 80,2 0,592 ANKRD11 domain 11

Small nucleolar RNA host gene (non- protein coding) 5930 0,0325837 0,3003688 20 33,8 0,592 SNHG5 5

phosphogluco 6836 0,0421013 0,3366308 19,6 33,1 0,592 PGM2L1 mutase 2-like 1 KIAA1702 208 0,0001876 0,0483249 287,8 486,8 0,591 KIAA1702 protein Forkhead box 1186 0,002086 0,0961653 19,4 32,8 0,591 FOXO3A O3A NLR family, pyrin domain 1753 0,0038875 0,1210936 22,1 37,4 0,591 NLRP3 containing 3 RING1 and YY1 binding 1754 0,0038877 0,1210936 378,6 640,1 0,591 RYBP protein

3731 0,0142397 0,2086721 230,9 391 0,591 SNX9 sorting nexin 9 ubiquitin- conjugating enzyme E2I (UBC9 homolog, 7016 0,043991 0,3428175 15 25,4 0,591 UBE2I yeast) zinc finger 2138 0,0054929 0,1404697 83,7 141,8 0,59 ZNF581 protein 581 caspase 1, apoptosis- related cysteine peptidase (interleukin 1, beta, 3327 0,0119575 0,1965014 95,3 161,6 0,59 CASP1 convertase) FAST kinase 4066 0,0168606 0,2266761 168,1 284,8 0,59 FASTKD5 domains 5

histone cluster 4612 0,0211399 0,2506123 5,9 10 0,59 HIST1H2AM 1, H2am 5326 0,0271357 0,27855 39,9 67,6 0,59 CUL1 Cullin 1 Family with sequence similarity 83, 5574 0,0293417 0,2878108 21,3 36,1 0,59 FAM83G member G modulator of 5593 0,0294742 0,2881284 282,9 479,6 0,59 MOAP1 apoptosis 1 argininosuccin ate synthetase 5689 0,0303605 0,2916051 10,2 17,3 0,59 ASS1 1 nucleolar and spindle associated 882 0,001283 0,079454 36,5 62 0,589 NUSAP1 protein 1 EPH receptor 3286 0,0117263 0,1950441 25,9 44 0,589 EPHB2 B2

CDV3 homolog 3411 0,0123909 0,1984223 210,7 357,9 0,589 CDV3 (mouse) ubiquitin specific 4363 0,0191335 0,2397717 37,1 63 0,589 USP42 peptidase 42

chromosome 1 open reading 5403 0,0278715 0,2820422 172,9 293,4 0,589 C1orf128 frame 128 trichorhinophal angeal 2136 0,0054901 0,1404697 37,3 63,4 0,588 TRPS1 syndrome I ribonuclease 2169 0,0056282 0,1417702 2193,6 3728,3 0,588 RNASET2 T2 fibroblast growth factor receptor 5489 0,02858 0,2846805 33,8 57,5 0,588 FRS2 substrate 2 coiled-coil domain 1076 0,0017775 0,0903205 187,2 318,8 0,587 CCDC59 containing 59 seven in absentia homolog 1 1277 0,0023387 0,1001319 32,3 55 0,587 SIAH1 (Drosophila)

zinc finger, CCHC domain 1914 0,0045308 0,1293195 29,8 50,8 0,587 ZCCHC6 containing 6 CD44 molecule (Indian blood group) /// mitogen- activated CD44 /// protein kinase 2254 0,0060485 0,146706 909,9 1549,9 0,587 MAPK10 10 zinc finger 3290 0,0117373 0,1950568 100,7 171,5 0,587 ZNF800 protein 800 S100 calcium binding protein 4884 0,0233211 0,2609998 3086,3 5260,8 0,587 S100A4 A4

small nucleolar RNA, H/ACA 5700 0,0304751 0,2923204 7,1 12,1 0,587 SNORA68 box 68

Adaptor- related protein complex 1, gamma 1 1014 0,0016083 0,0866252 22,4 38,2 0,586 AP1G1 subunit BAT2 domain 4409 0,0195373 0,2422309 36,4 62,1 0,586 BAT2D1 containing 1 150 0,0001257 0,0449393 35 59,8 0,585 TSPYL2 TSPY-like 2 intraflagellar transport 57 homolog (Chlamydomon 2198 0,0057712 0,1435306 47 80,3 0,585 IFT57 as) Ligand dependent nuclear receptor 2226 0,0058715 0,1441608 92,6 158,5 0,584 LCOR corepressor Solute carrier family 25, 5732 0,0308054 0,2937838 51,8 88,7 0,584 SLC25A37 member 37 7251 0,0465375 0,3509085 27,2 46,6 0,584 NRP2 neuropilin 2 selenoprotein 1732 0,0038005 0,1199725 270,6 464,2 0,583 SEPW1 W, 1 Exostoses 2357 0,0065604 0,1521301 10,9 18,7 0,583 EXT1 (multiple) 1

5808 0,0313478 0,2951 44,8 76,8 0,583 TUBB6 Tubulin, beta 6 mitogen- activated protein kinase kinase kinase 7 interacting 6593 0,0392347 0,3251671 7 12 0,583 MAP3K7IP3 protein 3

SMEK homolog 1, suppressor of mek1 7415 0,0482664 0,3558955 256,6 439,9 0,583 SMEK1 (Dictyostelium) development and differentiation enhancing 1332 0,0025226 0,1035459 584,7 1004,2 0,582 DDEF1 factor 1 GATA binding 1504 0,0030556 0,1109355 12,8 22 0,582 GATA2 protein 2 RNA binding motif protein 39 /// similar to RNA-binding region- containing protein 2 (Hepatocellular carcinoma protein 1) RBM39 /// (Splicing factor 2602 0,0079351 0,1666005 21,3 36,6 0,582 LOC643167 HCC1) solute carrier family 38, 4686 0,0217201 0,2534243 1428 2452,8 0,582 SLC38A2 member 2

GGT1 /// GGT2 /// GGTL4 /// LOC653590 /// LOC728226 /// 5675 0,0303058 0,2916051 35,3 60,7 0,582 LOC728441 NA

Jumonji, AT rich interactive 6024 0,0335854 0,3048276 39,4 67,7 0,582 JARID2 domain 2

7269 0,0467896 0,3519358 5,3 9,1 0,582 CD80 CD80 molecule phosphoinositi de-3-kinase, catalytic, beta 2094 0,0053137 0,1387424 22,7 39,1 0,581 PIK3CB polypeptide 3406 0,0123683 0,1984223 32,6 56,1 0,581 NRP1 Neuropilin 1 ELK4, ETS- domain protein (SRF accessory 6921 0,0429109 0,3389905 6,8 11,7 0,581 ELK4 protein 1) KIAA0999 339 0,0003437 0,0552439 5,8 10 0,58 KIAA0999 protein platelet- activating 583 0,0007032 0,0657513 121,4 209,8 0,579 PTAFR factor receptor ligand dependent nuclear receptor 1213 0,0021692 0,097762 133,2 230 0,579 LCOR corepressor

jumonji domain 2433 0,0069239 0,1555957 71,3 123,2 0,579 JMJD3 containing 3

Chromosome 7 open reading 4132 0,0173342 0,22922 6,2 10,7 0,579 C7orf44 frame 44

A kinase (PRKA) anchor 5050 0,0247425 0,2678729 7,3 12,6 0,579 AKAP13 protein 13 Transcribed 6636 0,039713 0,3271521 24,1 41,6 0,579 NA locus Poly(rC) binding protein 6980 0,0436451 0,3418002 80,3 138,6 0,579 PCBP2 2 SNF related 2578 0,0077941 0,1652859 183,1 316,6 0,578 SNRK kinase EH-domain 3020 0,0101218 0,1832282 13,7 23,7 0,578 EHD1 containing 1 extra spindle pole bodies homolog 1 (S. 4577 0,0208275 0,2487324 32,1 55,5 0,578 ESPL1 cerevisiae) CDNA clone IMAGE:479317 6785 0,0415872 0,3350862 9,6 16,6 0,578 NA 1 development and differentiation enhancing 948 0,0014348 0,0827269 816,7 1415,4 0,577 DDEF1 factor 1 family with sequence similarity 76, 2944 0,0096834 0,1796896 23,9 41,4 0,577 FAM76B member B Activating transcription 3137 0,0108434 0,1889066 6 10,4 0,577 ATF6 factor 6

Endoplasmic reticulum-golgi intermediate compartment 4780 0,022503 0,257391 11,3 19,6 0,577 ERGIC1 (ERGIC) 1 RAD50 homolog (S. 903 0,0013292 0,0804806 21,3 37 0,576 RAD50 cerevisiae) Chromosome 20 open reading frame 4382 0,0193482 0,241411 33,1 57,5 0,576 C20orf106 106 ubiquitin specific 741 0,0009782 0,0721769 27,9 48,5 0,575 USP36 peptidase 36 meningioma expressed antigen 5 (hyaluronidase 1083 0,0017982 0,0907817 165,1 287,2 0,575 MGEA5 ) G protein- coupled 2425 0,0069052 0,1555897 264,5 460,3 0,575 GPR35 receptor 35

START domain 2529 0,0074721 0,1615084 19,2 33,4 0,575 STARD10 containing 10 Transcribed 3589 0,013422 0,2043749 9,2 16 0,575 NA locus low density lipoprotein receptor- related protein 5494 0,028645 0,2850683 10 17,4 0,575 LRP5 5

BCL2/adenovir us E1B 19kDa interacting protein 3-like /// BCL2/adenovir us E1B 19kDa interacting 1405 0,0027237 0,1059917 983,2 1714 0,574 BNIP3L protein 3-like hypothetical 1437 0,0028183 0,1072307 59 102,7 0,574 LOC25845 LOC25845 KIAA0701 3575 0,0133638 0,2042096 7,8 13,6 0,574 KIAA0701 protein development and differentiation enhancing 163 0,0001371 0,0457736 458,6 800,9 0,573 DDEF1 factor 1 HEG homolog 968 0,0014909 0,0839343 78,4 136,8 0,573 HEG1 1 (zebrafish) folliculin interacting 4511 0,0203034 0,2460654 128,4 223,9 0,573 FNIP1 protein 1 Chromosome 10 open reading frame 5997 0,0333954 0,3043214 12,1 21,1 0,573 C10orf6 6 sex comb on midleg-like 1 3386 0,0122996 0,1984223 34,2 59,8 0,572 SCML1 (Drosophila) ubiquitin- conjugating enzyme variant 4472 0,0199812 0,2442435 201,1 351,8 0,572 Kua Kua solute carrier family 38, 5771 0,0310702 0,294362 707,2 1236,4 0,572 SLC38A2 member 2 A kinase (PRKA) anchor 7137 0,0452319 0,3464592 173,4 303,3 0,572 AKAP13 protein 13 Exostoses 320 0,0003236 0,0549787 9,7 17 0,571 EXT1 (multiple) 1 LATS, large tumor suppressor, homolog 2 1181 0,0020812 0,0961653 361,4 633,2 0,571 LATS2 (Drosophila)

polymerase (DNA directed) 2374 0,0066395 0,1528714 109,4 191,5 0,571 POLS sigma activin A receptor, type 2381 0,0066599 0,1529316 53,7 94,1 0,571 ACVR2A IIA

NADH dehydrogenas e (ubiquinone) 1 alpha subcomplex, 6784 0,0415808 0,3350862 9,6 16,8 0,571 NDUFA10 10, 42kDa

PTEN /// PTENP1 /// 473 0,0005264 0,0608476 309,5 543,3 0,57 LOC731292 NA synaptotagmin binding, cytoplasmic RNA interacting 1092 0,0018155 0,0908997 176,1 308,9 0,57 SYNCRIP protein selectin P 7245 0,0464983 0,3508908 184,3 323,3 0,57 SELPLG ligand

Full-length cDNA clone CS0DK005YO 12 of HeLa cells Cot 25- normalized of Homo sapiens 938 0,001418 0,082425 83,4 146,5 0,569 NA (human) similar to Six transmembran e epithelial antigen of 1714 0,0037402 0,1193068 10,7 18,8 0,569 MGC87042 prostate

glutamate- cysteine ligase, modifier subunit /// similar to GCLM /// MGC52679 3845 0,0152176 0,2163257 17,8 31,3 0,569 LOC440836 protein proteasome (prosome, macropain) 26S subunit, non-ATPase, 4079 0,0169684 0,2274448 51 89,6 0,569 PSMD11 11 Similar to Leo1, Paf1/RNA polymerase II complex component, 2771 0,0087909 0,1732398 10,4 18,3 0,568 LOC645620 homolog

AP1 gamma subunit binding 6602 0,0392768 0,325274 9,2 16,2 0,568 AP1GBP1 protein 1

cytochrome P450, family 2, subfamily U, polypeptide 1 /// family with sequence CYP2U1 /// similarity 116, 1028 0,0016594 0,0879972 15,3 27 0,567 FAM116B member B

jumonji domain 2969 0,0098197 0,180733 217,1 383,1 0,567 JMJD1C containing 1C ral guanine nucleotide dissociation 7035 0,044189 0,3433941 260,3 458,7 0,567 RALGDS stimulator

transducin-like enhancer of split 4 (E(sp1) homolog, 933 0,0014074 0,082425 6,9 12,2 0,566 TLE4 Drosophila) centrosome and spindle pole associated 2417 0,0068695 0,1553951 23,7 41,9 0,566 CSPP1 protein 1 Transcribed 2442 0,0069593 0,1558148 6,9 12,2 0,566 NA locus X-prolyl aminopeptidas e (aminopeptida se P) 3, 2604 0,0079424 0,1666005 10,3 18,2 0,566 XPNPEP3 putative Transcribed 2808 0,0089913 0,1750515 9,4 16,6 0,566 NA locus 2950 0,0097017 0,1798103 54,1 95,5 0,566 NA NA WEE1 homolog (S. 4359 0,0191076 0,239632 10,7 18,9 0,566 WEE1 pombe)

A kinase (PRKA) anchor 5064 0,0248579 0,2682755 255,6 451,2 0,566 AKAP13 protein 13 IKAROS family zinc finger 5 5410 0,0279231 0,2821988 60,6 107 0,566 IKZF5 (Pegasus) S100 calcium binding protein 6178 0,0352316 0,3117492 12 21,2 0,566 S100B B CD44 molecule (Indian blood group) /// mitogen- activated CD44 /// protein kinase 2015 0,0049455 0,1341912 513,6 909,1 0,565 MAPK10 10 PDZ domain 5308 0,0269704 0,2778083 24,4 43,2 0,565 PDZD8 containing 8 solute carrier family 25, 5782 0,0311829 0,2948337 246,7 436,5 0,565 SLC25A36 member 36 meningioma expressed antigen 5 (hyaluronidase 1267 0,0023005 0,0992515 99,4 176,1 0,564 MGEA5 ) fizzy/cell division cycle 20 related 1 1569 0,0032687 0,1138946 12,3 21,8 0,564 FZR1 (Drosophila)

TSC22 domain family, member 3990 0,016264 0,2228034 375,5 666,1 0,564 TSC22D2 2 gamma- glutamyltransfe 4424 0,019655 0,2428313 40,3 71,4 0,564 GGT1 rase 1 1715 0,0037434 0,1193068 11,1 19,7 0,563 06-sept septin 6

UDP- GlcNAc:betaG al beta-1,3-N- acetylglucosa minyltransferas 4793 0,0226035 0,2578256 638,8 1134,1 0,563 B3GNT5 e 5 hypoxia- inducible 4443 0,0197905 0,243428 126,3 224,6 0,562 HIG2 protein 2 zinc finger protein, X- 5980 0,0331818 0,3033352 23,5 41,8 0,562 ZFX linked kynureninase (L-kynurenine 6557 0,038843 0,3238431 261,3 465 0,562 KYNU hydrolase) Nuclear receptor subfamily 4, group A, 7050 0,0443529 0,3439709 58,7 104,5 0,562 NR4A2 member 2 POU domain, class 2, transcription 7445 0,0485444 0,3564596 16,2 28,8 0,562 POU2F2 factor 2 SH3-domain binding protein 3645 0,013693 0,2053417 88 156,8 0,561 SH3BP2 2 ankyrin repeat 1179 0,0020753 0,0961653 69,3 123,8 0,56 ANKRD12 domain 12 RAD50 homolog (S. 1924 0,0045558 0,1293549 41 73,2 0,56 RAD50 cerevisiae) Kruppel-like factor 5 2189 0,0057154 0,1427545 19,7 35,2 0,56 KLF5 (intestinal) RALBP1 associated Eps domain 3237 0,0114561 0,1934716 13,5 24,1 0,56 REPS2 containing 2 Baculoviral IAP repeat- 3500 0,0129498 0,2021636 45,4 81 0,56 BIRC3 containing 3

SMEK homolog 1, suppressor of mek1 4166 0,0176073 0,23108 142,3 254,3 0,56 SMEK1 (Dictyostelium) RAS protein activator like 1 4601 0,0210162 0,2497415 11,6 20,7 0,56 RASAL1 (GAP1 like) similar to splicing factor, arginine/serine- 467 0,0005154 0,0602236 197,6 353,5 0,559 FLJ11021 rich 4 sperm associated 1354 0,0025722 0,1038663 10 17,9 0,559 SPAG4 antigen 4 caspase 1, apoptosis- related cysteine peptidase (interleukin 1, beta, convertase) /// caspase-1 dominant- negative CASP1 /// inhibitor 3180 0,0111618 0,1919092 165,4 295,7 0,559 COP1 pseudo-ICE

vascular endothelial 4139 0,0173813 0,2295294 63,3 113,3 0,559 VEGFA growth factor A major histocompatibili ty complex, class II, DO 4583 0,0208703 0,2489466 20 35,8 0,559 HLA-DOA alpha myotubularin related protein 5467 0,0283917 0,283943 24,7 44,2 0,559 MTMR12 12 activating transcription factor 4 (tax- responsive enhancer 7223 0,04621 0,3497898 1078,7 1931,1 0,559 ATF4 element B67)

major histocompatibili ty complex, class II, DR beta 4 /// major histocompatibil ity complex, class II, DR 1748 0,0038621 0,1208011 43,5 78 0,558 HLA-DRB4 beta 4

cytochrome P450, family 2, subfamily R, 1761 0,0039082 0,1213406 15,9 28,5 0,558 CYP2R1 polypeptide 1 trophoblast- derived noncoding 6728 0,0409734 0,3329651 696,4 1248,8 0,558 TncRNA RNA

A kinase (PRKA) anchor 2012 0,0049363 0,1341413 44,9 80,6 0,557 AKAP8L protein 8-like Chromosome 16 open reading frame 4130 0,0173247 0,22922 76,2 136,9 0,557 C16orf72 72 ring finger 4671 0,021613 0,2529845 104,4 187,6 0,557 RNF12 protein 12 C-type lectin domain family 6515 0,0384206 0,3223518 24,1 43,3 0,557 CLEC4E 4, member E chromosome 16 open reading frame 6603 0,0392892 0,3253274 156,6 280,9 0,557 C16orf76 76

dual specificity 2787 0,0088656 0,1739242 12,4 22,3 0,556 DUSP8 phosphatase 8 Wilms tumor 1 associated 3335 0,0120153 0,1969251 7 12,6 0,556 WTAP protein chromosome 21 open reading frame 3681 0,0139395 0,2070136 18,9 34 0,556 C21orf91 91 ELK3, ETS- domain protein (SRF accessory 3766 0,014523 0,2108234 140,8 253,3 0,556 ELK3 protein 2) chromosome 14 open reading frame 2316 0,0063495 0,1498086 86,7 156,2 0,555 C14orf138 138 cytochrome P450, family 1, subfamily B, 2798 0,00895 0,1748897 3851,3 6941,2 0,555 CYP1B1 polypeptide 1 nuclear fragile X mental retardation protein interacting 4167 0,0176136 0,2311072 144,8 261,1 0,555 NUFIP2 protein 2

NGFI-A binding protein 1 (EGR1 binding protein 4286 0,0185272 0,236345 44 79,3 0,555 NAB1 1) Thyroid hormone receptor associated 7254 0,0465683 0,3509956 26,4 47,6 0,555 THRAP1 protein 1 phosphatase and tensin homolog (mutated in multiple advanced 571 0,0006715 0,0642982 366,2 661,5 0,554 PTEN cancers 1) bromodomain 992 0,0015562 0,0856868 36,2 65,3 0,554 BRD1 containing 1 Superoxide dismutase 2, 1051 0,0017011 0,0884944 784,2 1414,7 0,554 SOD2 mitochondrial 2149 0,0055531 0,1412675 65,3 117,8 0,554 CUL1 Cullin 1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 4693 0,0217782 0,2537232 5,6 10,1 0,554 SERPINE1 1), member 1 Wilms tumor 1 associated 606 0,0007337 0,0657513 12 21,7 0,553 WTAP protein zinc finger, SWIM-type 1038 0,0016756 0,0881582 484,2 876 0,553 ZSWIM6 containing 6

MAFG /// 4833 0,0228775 0,2587788 37,3 67,4 0,553 LOC644132 NA gamma- glutamyltransfe 5039 0,024637 0,2673205 43,8 79,2 0,553 GGT1 rase 1

coenzyme Q10 homolog B (S. 5965 0,032927 0,3017912 243,6 440,4 0,553 COQ10B cerevisiae) intercellular adhesion molecule 4 (Landsteiner- Wiener blood 7196 0,0459467 0,3490747 45,9 83 0,553 ICAM4 group)

MYST histone acetyltransfera se (monocytic 428 0,0004561 0,0577884 13,3 24,1 0,552 MYST3 leukemia) 3 zinc finger 1062 0,001734 0,0892716 209,1 379,1 0,552 ZNF394 protein 394 leucine rich repeat containing 8 family, member 3019 0,0101158 0,1832002 99,6 180,4 0,552 LRRC8C C protein kinase, cAMP- dependent, regulatory, 3383 0,0122773 0,1984219 30,8 55,8 0,552 PRKAR2B type II, beta interleukin-1 receptor- associated 3464 0,0126822 0,200173 33,6 60,9 0,552 IRAK3 kinase 3 Far upstream element (FUSE) binding protein 6073 0,034081 0,30683 28,2 51,1 0,552 FUBP1 1

SPT2, Suppressor of Ty, domain containing 1 6141 0,0348604 0,3103541 56,1 101,6 0,552 SPTY2D1 (S. cerevisiae) chemokine (C- X-C motif) ligand 1 (melanoma growth stimulating 7464 0,0487567 0,3571507 5,8 10,5 0,552 CXCL1 activity, alpha) N-acetylated alpha-linked acidic dipeptidase- 335 0,0003399 0,0552439 17,4 31,6 0,551 NAALADL1 like 1 chromosome 10 open reading frame 490 0,0005607 0,0624087 61,9 112,3 0,551 C10orf78 78

jumonji domain 592 0,0007173 0,0657513 267,2 484,9 0,551 JMJD1A containing 1A interleukin 1 receptor accessory 1256 0,0022653 0,0986109 99,6 180,9 0,551 IL1RAP protein insulin-like growth factor 2 mRNA binding 4273 0,0183632 0,2349656 68,4 124,1 0,551 IGF2BP2 protein 2 4731 0,0220422 0,2547363 108 195,9 0,551 JUN Jun oncogene

Prolyl 5999 0,0334002 0,3043214 13,5 24,5 0,551 PREP endopeptidase coiled-coil domain 901 0,0013265 0,0804304 305,9 555,9 0,55 CCDC59 containing 59 chromodomain helicase DNA binding protein 1563 0,0032601 0,1138946 90,5 164,6 0,55 CHD1 1 1959 0,0046766 0,1305223 27,8 50,5 0,55 NA NA nucleoporin 2249 0,0060224 0,1463492 89,5 162,8 0,55 NUP50 50kDa transmembran e channel-like 6595 0,0392383 0,3251671 23,6 42,9 0,55 TMC4 4 PHD finger protein 1 /// deleted in lung and PHF1 /// esophageal 368 0,0003874 0,0575573 260,2 473,7 0,549 DLEC1 cancer 1 zinc finger 2485 0,0072368 0,1592242 150,5 274,3 0,549 ZNF385 protein 385 ring finger 3027 0,0101665 0,1835023 64,3 117,2 0,549 RNF24 protein 24

Neutral sphingomyelin ase (N-SMase) activation associated 3056 0,0103884 0,1857717 19,5 35,5 0,549 NSMAF factor gamma- glutamyltransfe 3200 0,0112981 0,1929329 42,6 77,6 0,549 GGT1 rase 1 zinc finger, RAN-binding domain 3825 0,0150122 0,2145683 118,7 216,3 0,549 ZRANB1 containing 1 interleukin 2 receptor, gamma (severe combined immunodeficie 4536 0,0205308 0,2474695 129,4 235,6 0,549 IL2RG ncy) Cystatin B 5508 0,0288365 0,2861008 62,5 113,8 0,549 CSTB (stefin B) chromosome 20 open reading frame 1903 0,0044901 0,1289211 230,1 420,2 0,548 C20orf111 111 solute carrier family 38, 5300 0,0269087 0,2775883 625,3 1141,3 0,548 SLC38A2 member 2 Family with sequence similarity 107, 2392 0,0067271 0,153734 7 12,8 0,547 FAM107B member B mitogen- activated protein kinase kinase kinase 3614 0,0135209 0,2045532 67,6 123,5 0,547 MAP3K2 2 solute carrier family 9 (sodium/hydro gen exchanger), 5055 0,0247775 0,2679486 31,7 58 0,547 SLC9A9 member 9 cytidine and dCMP deaminase domain 1673 0,0035961 0,1175235 60,5 110,9 0,546 CDADC1 containing 1 Interferon- related developmental 5940 0,0326662 0,3006775 21,9 40,1 0,546 IFRD1 regulator 1 chromosome 10 open reading frame 2065 0,0051862 0,1372509 49,2 90,4 0,544 C10orf54 54 Guanine nucleotide binding protein (G protein), beta polypeptide 2- 3553 0,0131882 0,2029454 38,3 70,4 0,544 GNB2L1 like 1

spen homolog, transcriptional regulator 3586 0,0134045 0,2043749 77,8 143,1 0,544 SPEN (Drosophila)

G protein- coupled receptor kinase 4439 0,0197578 0,2433561 125,8 231,3 0,544 GIT2 interactor 2 pleckstrin homology domain containing, family O 5079 0,0250114 0,2691969 428,4 787,8 0,544 PLEKHO1 member 1

tumor necrosis factor (ligand) superfamily, 4084 0,0170038 0,2276402 1072,2 1973,6 0,543 TNFSF13B member 13b PTC7 protein phosphatase homolog (S. 4196 0,0177935 0,2318066 904,5 1664,4 0,543 PPTC7 cerevisiae) sema domain, immunoglobuli n domain (Ig), transmembran e domain (TM) and short cytoplasmic domain, (semaphorin) 6134 0,0348103 0,3102793 12,7 23,4 0,543 SEMA4A 4A Sterile alpha motif domain 6150 0,0349671 0,310829 92,3 170,1 0,543 SAMD8 containing 8 ADP- ribosylation 91 6,23E-05 0,0367348 345,8 638,1 0,542 ARF6 factor 6

transducin-like enhancer of split 4 (E(sp1) homolog, 461 0,0005061 0,0600239 36,2 66,8 0,542 TLE4 Drosophila) hypothetical protein 2469 0,0071187 0,1575884 14,3 26,4 0,542 LOC283567 LOC283567 5248 0,0264585 0,2756514 28,3 52,2 0,542 NPTN Neuroplastin Kruppel-like 6340 0,0368679 0,317942 182,3 336,4 0,542 KLF11 factor 11 Inhibitor of DNA binding 2, dominant negative helix- loop-helix 777 0,0010748 0,0753005 13,2 24,4 0,541 ID2 protein C-type lectin domain family 1358 0,0025913 0,1040748 282,4 522,1 0,541 CLEC7A 7, member A Wilms tumor 1 associated 2300 0,0062672 0,1489822 496,3 918,2 0,541 WTAP protein 6346 0,0369357 0,3181373 28,2 52,1 0,541 TNS1 tensin 1 major histocompatibili ty complex, class II, DP 6925 0,0429709 0,3392502 2306,4 4264,3 0,541 HLA-DPB1 beta 1 Transcribed 1620 0,0034437 0,1161645 12,1 22,4 0,54 NA locus X-prolyl aminopeptidas e (aminopeptida se P) 2, membrane- 1798 0,0040579 0,1233958 18,4 34,1 0,54 XPNPEP2 bound

Notch homolog 2502 0,0073156 0,1597509 30 55,6 0,54 NOTCH2 2 (Drosophila) MOB1, Mps One Binder kinase activator-like 6004 0,0334257 0,3043214 77,2 142,9 0,54 MOBKL2B 2B (yeast)

UDP- GlcNAc:betaG al beta-1,3-N- acetylglucosa minyltransferas 7147 0,0453 0,3464592 40,4 74,8 0,54 B3GNT5 e 5

jumonji domain 658 0,0008328 0,0691996 300,6 557,7 0,539 JMJD1C containing 1C membrane bound O- acyltransferase domain 1195 0,0021227 0,0970402 17,4 32,3 0,539 MBOAT2 containing 2

katanin p60 2519 0,0074146 0,1609342 13,1 24,3 0,539 KATNAL1 subunit A-like 1 toll-like receptor adaptor 2761 0,0087439 0,173152 42,6 79 0,539 TICAM2 molecule 2 hypothetical gene supported by 2961 0,009772 0,1804053 9,7 18 0,539 LOC399900 AK093779 CD109 4404 0,0195161 0,2422309 17,1 31,7 0,539 CD109 molecule

leucine rich repeat (in FLII) interacting 6105 0,0344742 0,3086141 17,4 32,3 0,539 LRRFIP2 protein 2 transducin (beta)-like 1X- 7349 0,0476412 0,3544004 106,6 197,6 0,539 TBL1X linked 605 0,0007325 0,0657513 15,9 29,6 0,537 NA NA ankyrin repeat 3900 0,0155802 0,2184224 47,6 88,7 0,537 ANKRD12 domain 12 zinc finger protein, X- linked /// zinc finger protein, 4034 0,0166439 0,2255591 7,3 13,6 0,537 ZFX /// ZFY Y-linked Transcribed 346 0,0003496 0,0552439 33,3 62,2 0,535 NA locus RING1 and YY1 binding 1067 0,0017614 0,0902138 565,6 1057,1 0,535 RYBP protein family with sequence similarity 100, 1491 0,0029885 0,1095772 133,5 249,6 0,535 FAM100B member B 2447 0,0070374 0,1571828 42,3 79 0,535 NA NA hypothetical protein 4849 0,0229863 0,2591825 470,1 878,4 0,535 MGC7036 MGC7036 histone cluster HIST1H2BG 1, H2bg /// /// histone cluster 6326 0,0367516 0,3176405 9,2 17,2 0,535 HIST1H2BC 1, H2bc mitogen- activated protein kinase kinase kinase 6501 0,0383178 0,322196 16,8 31,4 0,535 MAP3K6 6 H2A histone family, member 511 0,0005895 0,0630742 245,7 460,5 0,534 H2AFY Y arachidonate 15- 2757 0,0087106 0,1727429 346,4 648,5 0,534 ALOX15 lipoxygenase

Fc fragment of IgG, low affinity IIa, receptor 4934 0,023704 0,2626705 11,7 21,9 0,534 FCGR2A (CD32) RB1-inducible 183 0,0001636 0,0481428 236,4 443,4 0,533 RB1CC1 coiled-coil 1 myeloid/lymph oid or mixed- lineage leukemia 5 (trithorax homolog, 763 0,0010386 0,0744239 297,7 558,5 0,533 MLL5 Drosophila) nucleoporin 980 0,0015187 0,0847295 54,6 102,4 0,533 NUP50 50kDa zinc finger, MIZ- type containing 7215 0,0461501 0,3496655 992,6 1862,7 0,533 ZMIZ1 1 chromosome 15 open reading frame 684 0,0008803 0,0701954 46,2 86,9 0,532 C15orf39 39 NLR family, pyrin domain 1467 0,0029347 0,1093314 92,5 173,8 0,532 NLRP3 containing 3

calmodulin regulated spectrin- CAMSAP1L associated 1803 0,0040809 0,1237511 22,2 41,7 0,532 1 protein 1-like 1 DNA cross-link repair 1B (PSO2 homolog, S. 1972 0,0047425 0,1314555 48,1 90,4 0,532 DCLRE1B cerevisiae)

vitamin D (1,25- dihydroxyvitam 3405 0,0123664 0,1984223 95,9 180,4 0,532 VDR in D3) receptor metallothionein 7416 0,0482842 0,3559788 213,8 401,6 0,532 MT1G 1G Protein phosphatase 2, regulatory subunit B (B56), gamma 3736 0,014273 0,2087933 57,6 108,5 0,531 PPP2R5C isoform Ras association (RalGDS/AF-6) domain family 4390 0,0194321 0,2419481 42,6 80,2 0,531 RASSF5 5

Splicing factor, arginine/serine- rich 2, interacting 6874 0,0423546 0,3368398 113,2 213,3 0,531 SFRS2IP protein AT rich interactive domain 5A 1295 0,0024219 0,1022034 60,5 114,1 0,53 ARID5A (MRF1-like) bromodomain 1615 0,0034286 0,116061 309,2 583,2 0,53 BRD2 containing 2

Integrin, alpha V (vitronectin receptor, alpha polypeptide, 4429 0,0196816 0,2429649 43,3 81,7 0,53 ITGAV antigen CD51) platelet- activating factor acetylhydrolas e, isoform Ib, alpha subunit 6395 0,0372705 0,3186497 186,1 351,4 0,53 PAFAH1B1 45kDa metastasis 1582 0,003305 0,1142231 15,4 29,1 0,529 MTSS1 suppressor 1 kelch-like 24 2280 0,0061859 0,1483395 114,7 216,9 0,529 KLHL24 (Drosophila) AT rich interactive domain 3B 3274 0,0116239 0,1940988 34,2 64,8 0,528 ARID3B (BRIGHT-like) suppressor of cytokine 4342 0,0189628 0,2387819 41,4 78,4 0,528 SOCS2 signaling 2

ADP- ribosylation factor GTPase activating 5232 0,026359 0,2754224 16,1 30,5 0,528 ARFGAP3 protein 3 yippee-like 5 1134 0,0019654 0,0946254 678,4 1286,1 0,527 YPEL5 (Drosophila) myeloid/lymph oid or mixed- lineage leukemia 5 (trithorax homolog, 1839 0,0042246 0,1254704 87,7 166,4 0,527 MLL5 Drosophila) hypothetical protein MGC40405 /// hypothetical MGC40405 protein /// LOC728066 /// LOC728066 hypothetical /// protein 2970 0,0098207 0,180733 214,1 406,4 0,527 LOC728153 LOC728153 pleiomorphic adenoma gene- 4563 0,0207103 0,248156 31,1 59 0,527 PLAGL2 like 2 ankyrin repeat 5211 0,0261678 0,2745585 106,2 201,7 0,527 ANKRD12 domain 12 nucleoporin 2019 0,004992 0,1351845 161,8 307,6 0,526 NUP153 153kDa anthrax toxin 2635 0,0080775 0,167497 544,5 1035,9 0,526 ANTXR2 receptor 2 cysteine-rich secretory protein LCCL domain 3168 0,0110441 0,1906049 10,3 19,6 0,526 CRISPLD2 containing 2 junction 4518 0,0203433 0,2461863 41,9 79,6 0,526 JUP plakoglobin Casein kinase 5204 0,0261383 0,2745585 110,6 210,4 0,526 CSNK1A1 1, alpha 1 ADAM metallopeptida se domain 8 /// ADAM metallopeptida 268 0,0002567 0,0523697 11,5 21,9 0,525 ADAM8 se domain 8

guanine nucleotide binding protein (G protein), alpha 15 (Gq 607 0,0007342 0,0657513 133,4 254,3 0,525 GNA15 class) ST3 beta- galactoside alpha-2,3- sialyltransferas 1427 0,0027968 0,1071379 53,1 101,1 0,525 ST3GAL1 e 1 myotubularin related protein 3369 0,0122237 0,1983671 22,3 42,5 0,525 MTMR11 11

calmodulin regulated spectrin- CAMSAP1L associated 5254 0,0265395 0,2760755 55,7 106 0,525 1 protein 1-like 1 Proline rich Gla (G- carboxyglutami c acid) 4 (transmembran 1087 0,001807 0,0908903 69 131,6 0,524 PRRG4 e) vitelline membrane outer layer 1 homolog 1595 0,0033624 0,1152597 8,7 16,6 0,524 VMO1 (chicken)

aldehyde dehydrogenas e 2 family 1709 0,0037213 0,1190533 324,4 618,5 0,524 ALDH2 (mitochondrial) Chromosome 18 open reading frame 2632 0,0080705 0,167497 31,3 59,7 0,524 C18orf17 17

4517 0,0203413 0,2461863 153,8 293,3 0,524 CD37 CD37 molecule iduronate 2- sulfatase (Hunter 1176 0,0020714 0,0961653 99,6 190,4 0,523 IDS syndrome) cofactor required for Sp1 transcriptional activation, subunit 7, 960 0,0014748 0,0839343 112,4 215,4 0,522 CRSP7 70kDa intercellular adhesion 1164 0,002033 0,0954208 53,3 102,2 0,522 ICAM2 molecule 2 1889 0,0044515 0,128789 144,9 277,8 0,522 FLOT1 flotillin 1 La ribonucleoprot ein domain family, member 2437 0,0069489 0,1557913 39,9 76,5 0,522 LARP2 2 zinc finger 2729 0,0085493 0,1712836 109,6 209,8 0,522 ZNF508 protein 508

4407 0,019527 0,2422309 250,3 479,5 0,522 CD58 CD58 molecule chromosome 18 open reading frame 6194 0,0353429 0,311975 89,7 171,9 0,522 C18orf1 1 eukaryotic translation initiation factor 1248 0,0022518 0,0986109 2498,1 4794,3 0,521 EIF1 1 gamma- glutamyltransfe rase-like 2524 0,0074368 0,1610963 24,3 46,6 0,521 GGTLA4 activity 4 mitogen- activated protein kinase kinase kinase 7468 0,0488329 0,3574318 24 46,1 0,521 MAP4K1 kinase 1 CD44 molecule (Indian blood 714 0,0009292 0,0708877 965,5 1855 0,52 CD44 group) CD44 molecule (Indian blood 776 0,0010747 0,0753005 983,7 1890,1 0,52 CD44 group) 1422 0,0027782 0,10682 12,8 24,6 0,52 LMNB1 lamin B1

myeloid cell leukemia sequence 1 1649 0,0035082 0,1161645 1423,7 2739,2 0,52 MCL1 (BCL2-related)

cytochrome P450, family 1, subfamily B, 2092 0,005311 0,1387424 1781,6 3429 0,52 CYP1B1 polypeptide 1 cystatin C (amyloid angiopathy and cerebral 2489 0,0072643 0,1595295 1765,6 3393,9 0,52 CST3 hemorrhage) transmembran 2515 0,0073892 0,160638 79,8 153,6 0,52 TMEM51 e protein 51 cytotoxic T- lymphocyte- associated 3970 0,0161056 0,221807 24,5 47,1 0,52 CTLA4 protein 4 bromodomain 4554 0,020641 0,2478144 78,4 150,8 0,52 BRD2 containing 2 nucleoporin 4855 0,0230617 0,2597113 26 50 0,52 NUP50 50kDa Actinin, alpha 7206 0,0460653 0,3494369 34 65,4 0,52 ACTN4 4 4290 0,0185713 0,2366142 25,2 48,6 0,519 NA NA WD repeat 6108 0,0344845 0,3086141 8,1 15,6 0,519 WDR20 domain 20

tumor necrosis factor, alpha- induced 533 0,0006286 0,0635709 503,7 972,6 0,518 TNFAIP8 protein 8

spen homolog, transcriptional regulator 958 0,0014709 0,0839343 182,6 352,6 0,518 SPEN (Drosophila) chromosome 18 open reading frame 1912 0,0045244 0,1293195 38,8 74,9 0,518 C18orf1 1

Integrin, alpha V (vitronectin receptor, alpha polypeptide, 2257 0,0060579 0,1467504 54,9 106 0,518 ITGAV antigen CD51) T-cell activation GTPase activating 3627 0,0136036 0,2050667 20 38,6 0,518 TAGAP protein absent in 3831 0,0150715 0,2150241 11,6 22,4 0,518 AIM2 melanoma 2 protein phosphatase 1F (PP2C domain 252 0,0002365 0,0513121 168,6 326,2 0,517 PPM1F containing)

solute carrier family 6 (neurotransmitt er transporter, creatine), 1479 0,002967 0,109553 40,3 78 0,517 SLC6A8 member 8 hypothetical protein 3714 0,0141439 0,2082169 13,6 26,3 0,517 LOC643079 LOC643079 calpain 2, (m/II) large 6307 0,0365924 0,3172173 21,4 41,4 0,517 CAPN2 subunit G protein- coupled 7357 0,0477227 0,3546607 34,3 66,4 0,517 GPR157 receptor 157 G protein- coupled 3781 0,014604 0,2111806 31,5 61,1 0,516 GPR68 receptor 68 sterile alpha motif domain 5854 0,0317955 0,296902 69,2 134,2 0,516 SAMD4B containing 4B CD44 molecule (Indian blood 734 0,0009679 0,0720258 649,6 1262,3 0,515 CD44 group) eukaryotic translation initiation factor 977 0,0015147 0,0846932 2433,4 4723,1 0,515 EIF1 1 NLR family, pyrin domain 1293 0,002418 0,1022034 12,1 23,5 0,515 NLRP1 containing 1 Alstrom 1910 0,0045143 0,1292248 5,1 9,9 0,515 ALMS1 syndrome 1

protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, 2488 0,007256 0,1594541 65,4 127 0,515 PPP3R1 type I)

chromosome 9 open reading 1168 0,0020497 0,0959481 81,9 159,4 0,514 C9orf72 frame 72 WD repeat 2119 0,0054045 0,1394483 139,6 271,4 0,514 WDR33 domain 33 chromosome 20 open reading frame 3509 0,012977 0,2021636 16,9 32,9 0,514 C20orf74 74 beta-1,3-N- acetylgalactos aminyltransfer ase 1 (globoside 5498 0,0286749 0,2851583 12,9 25,1 0,514 B3GALNT1 blood group) F-box protein 1750 0,0038808 0,1210936 179,2 349,3 0,513 FBXO34 34

macrophage migration inhibitory factor (glycosylation- inhibiting 3755 0,0143942 0,209588 1307,2 2546,3 0,513 MIF factor) Pellino homolog 1 4915 0,0235464 0,2619327 24,6 48 0,513 PELI1 (Drosophila) Kruppel-like 7335 0,047465 0,3538035 78,3 152,7 0,513 KLF9 factor 9 yippee-like 5 826 0,0011694 0,0774055 445,1 869,6 0,512 YPEL5 (Drosophila) Activating transcription factor 7 interacting 3326 0,0119569 0,1965014 54,9 107,3 0,512 ATF7IP2 protein 2 FERM, RhoGEF and pleckstrin domain protein 7538 0,049571 0,3595509 19,6 38,3 0,512 FARP2 2 protein phosphatase 1F (PP2C domain 85 5,68E-05 0,0365358 181,7 355,7 0,511 PPM1F containing) Kinase suppressor of 424 0,0004513 0,0577884 42,8 83,8 0,511 KSR1 ras 1 zinc finger 789 0,001091 0,0756026 214,7 419,8 0,511 ZNF508 protein 508 eukaryotic translation initiation factor 1008 0,0015918 0,0863409 2420,2 4736,3 0,511 EIF1 1 bromodomain 1037 0,0016709 0,0880969 398,6 780,5 0,511 BRD2 containing 2 Hypothetical protein 3266 0,0115732 0,1936505 9,1 17,8 0,511 FLJ43806 FLJ43806

chromosome 7 open reading 5274 0,0266863 0,276654 79,3 155,3 0,511 C7orf40 frame 40 DCP2 decapping enzyme homolog (S. 3632 0,0136495 0,2052986 104,5 205 0,51 DCP2 cerevisiae) 1077 0,0017794 0,0903331 150,2 295 0,509 FLOT1 flotillin 1 SCO cytochrome oxidase deficient homolog 2 2115 0,0053955 0,1393516 188,3 369,9 0,509 SCO2 (yeast) proteolipid protein 2 (colonic epithelium- 2247 0,006018 0,1463492 386,2 759,1 0,509 PLP2 enriched)

aspartate beta- 3033 0,0102019 0,1839067 11,9 23,4 0,509 ASPH hydroxylase Protein tyrosine phosphatase, non-receptor 6043 0,0338118 0,3059176 21,5 42,2 0,509 PTPN1 type 1 transmembran 6652 0,0399397 0,328276 99,9 196,2 0,509 TMEM23 e protein 23 4053 0,0167989 0,2265502 2898,3 5707,5 0,508 ANXA1 annexin A1

transducin-like enhancer of split 4 (E(sp1) homolog, 4200 0,017855 0,2324045 43,5 85,7 0,508 TLE4 Drosophila)

signal transducer and activator of transcription 1, 5384 0,0276451 0,2806264 96,2 189,5 0,508 STAT1 91kDa splicing factor proline/glutami ne-rich (polypyrimidine tract binding protein 7410 0,0482353 0,3558862 471,3 927 0,508 SFPQ associated) valosin containing protein (p97)/p47 complex interacting 972 0,001493 0,0839343 34,3 67,6 0,507 VCPIP1 protein 1 family with sequence similarity 107, 4662 0,0215036 0,2521899 371,2 731,9 0,507 FAM107B member B chromosome 21 open reading frame 4985 0,0241733 0,2650734 37,9 74,7 0,507 C21orf124 124 yippee-like 3 5857 0,0318053 0,296902 65 128,1 0,507 YPEL3 (Drosophila) thyroid hormone receptor associated 845 0,0012228 0,0791194 110,2 217,9 0,506 THRAP2 protein 2 Chromodomai n helicase DNA binding protein 3812 0,0148771 0,2133802 8,6 17 0,506 CHD2 2 procollagen- proline, 2- oxoglutarate 4- dioxygenase (proline 4- hydroxylase), alpha 4329 0,0188128 0,2376045 366,7 725,4 0,506 P4HA1 polypeptide I SEC31 homolog A (S. 5194 0,0259911 0,2735971 107,2 211,7 0,506 SEC31A cerevisiae) 7559 0,0498657 0,3606489 36,5 72,2 0,506 IL15 interleukin 15 860 0,0012483 0,0791194 27,9 55,2 0,505 KIAA1128 KIAA1128 EH-domain 3962 0,0160137 0,2209866 15,4 30,5 0,505 EHD1 containing 1 cAMP responsive element binding protein 4887 0,0233522 0,261228 5,3 10,5 0,505 CREB5 5

asialoglycoprot 5524 0,0289452 0,2864915 43,5 86,1 0,505 ASGR2 ein receptor 2 BTB (POZ) domain 6317 0,036678 0,317456 14,2 28,1 0,505 BTBD7 containing 7 7290 0,0470042 0,3525315 33 65,4 0,505 NA NA

chromosome 9 open reading 683 0,000879 0,0701954 184,6 366,3 0,504 C9orf21 frame 21 solute carrier family 29 (nucleoside transporters), 993 0,0015564 0,0856868 45,2 89,6 0,504 SLC29A1 member 1

Chromosome X open reading 5575 0,0293606 0,2879445 45,8 90,8 0,504 CXorf45 frame 45 7199 0,0459623 0,3490747 12,3 24,4 0,504 NA NA

Spectrin repeat containing, nuclear 6660 0,0400593 0,3288652 82,8 164,7 0,503 SYNE1 envelope 1

Activin A 1436 0,0028139 0,1071379 10,7 21,3 0,502 ACVR1 receptor, type I 1734 0,003806 0,1199919 40,8 81,3 0,502 TSPAN3 Tetraspanin 3 Ras-like without CAAX 4235 0,0181038 0,233725 406,4 809,8 0,502 RIT1 1

Phosphatidylin ositol transfer 5238 0,0264058 0,2755518 31,5 62,7 0,502 PITPNB protein, beta solute carrier family 2 (facilitated glucose transporter), 6035 0,0336946 0,3052614 47,8 95,2 0,502 SLC2A1 member 1 forkhead box 395 0,0004174 0,0577756 326 650,7 0,501 FOXO3A O3A G protein- coupled 864 0,0012573 0,0791194 21,9 43,7 0,501 GPR132 receptor 132 spermidine/spe rmine N1- acetyltransfera 931 0,001405 0,082425 1310,6 2617 0,501 SAT1 se 1 splicing factor proline/glutami ne-rich (polypyrimidine tract binding protein 1167 0,0020476 0,0959319 283,9 566,2 0,501 SFPQ associated) testis derived transcript (3 1555 0,0032434 0,1138946 85 169,5 0,501 TES LIM domains) Ubiquitin specific 2229 0,0058838 0,1443234 17,2 34,3 0,501 USP12 peptidase 12 N- acetyltransfera 7122 0,0450777 0,3460577 131,9 263,5 0,501 NAT13 se 13 peptidylprolyl isomerase A 429 0,0004562 0,0577884 11,7 23,4 0,5 PPIA (cyclophilin A)

tumor necrosis factor, alpha- induced 728 0,0009561 0,071715 581,9 1164,5 0,5 TNFAIP8 protein 8 fascin homolog 1, actin- bundling protein (Strongylocentr otus 2230 0,0059004 0,1446021 8 16 0,5 FSCN1 purpuratus) zinc finger protein 36, C3H type-like 4832 0,02287 0,2587784 31,9 63,8 0,5 ZFP36L1 1 DCP1 decapping enzyme homolog A (S. 2166 0,0056237 0,1417702 96,8 193,9 0,499 DCP1A cerevisiae) Transcribed 5738 0,030838 0,2937838 37,7 75,5 0,499 NA locus

SON DNA 505 0,000581 0,0628117 114,1 229 0,498 SON binding protein zinc finger, AN1-type 748 0,0009976 0,0729195 1409,8 2830,1 0,498 ZFAND5 domain 5 chemokine (C- C motif) ligand 3739 0,0142815 0,2088369 56,3 113,3 0,497 CCL13 13

hexamethylene bis-acetamide 4431 0,0197006 0,2430897 119,6 240,7 0,497 HEXIM1 inducible 1 363 0,0003781 0,0569494 35 70,6 0,496 KIAA1712 KIAA1712 major histocompatibili ty complex, 840 0,0012152 0,0790355 461,8 930,9 0,496 HLA-E class I, E hypothetical protein 1800 0,0040694 0,123608 28,2 56,8 0,496 MGC20983 MGC20983 ATP-binding cassette, sub- family G (WHITE), 3927 0,0157549 0,219353 11,1 22,4 0,496 ABCG1 member 1 splicing factor, arginine/serine- rich 10 (transformer 2 homolog, 1921 0,00455 0,1293549 93,4 188,8 0,495 SFRS10 Drosophila) Restin (Reed- Steinberg cell- expressed intermediate filament- associated 2764 0,0087574 0,1732311 32,3 65,3 0,495 RSN protein) CDNA FLJ30141 fis, clone BRACE200014 4779 0,0224752 0,2571315 9,1 18,4 0,495 NA 8 intercellular adhesion molecule 1 (CD54), human rhinovirus 3547 0,0131653 0,2028614 38,9 78,7 0,494 ICAM1 receptor

jumonji domain 5621 0,0297254 0,2891181 19,6 39,7 0,494 JMJD3 containing 3 cytoplasmic polyadenylatio n element binding protein 667 0,0008507 0,0697147 48 97,3 0,493 CPEB2 2

lectin, galactoside- binding, soluble, 3 1434 0,0028132 0,1071379 39,6 80,3 0,493 LGALS3BP binding protein Yippee-like 5 1784 0,0039999 0,1225866 36,7 74,4 0,493 YPEL5 (Drosophila) KIAA1659 3169 0,0110495 0,1906379 10,9 22,1 0,493 KIAA1659 protein development and differentiation enhancing 61 3,97E-05 0,0353731 133,3 271,1 0,492 DDEF1 factor 1

tumor necrosis factor (ligand) superfamily, member 10 /// tumor necrosis factor (ligand) superfamily, 1499 0,0030391 0,1108491 6 12,2 0,492 TNFSF10 member 10

Wiskott-Aldrich 2429 0,0069139 0,1555897 77,2 156,9 0,492 WASL syndrome-like

vascular endothelial 2670 0,0082492 0,1689232 26,1 53 0,492 VEGFA growth factor A sterile alpha motif domain 4611 0,0211339 0,2505955 16,1 32,7 0,492 SAMD8 containing 8 phosphatidylse 5236 0,0263853 0,2755188 258,5 525 0,492 PTDSR rine receptor IBR domain 7390 0,0479912 0,3550265 31,2 63,4 0,492 IBRDC2 containing 2 single- stranded DNA binding protein 1329 0,0025194 0,1035459 34,3 69,9 0,491 SSBP2 2

ATPase, Ca++ transporting, plasma 1578 0,0032996 0,1142231 56,9 115,8 0,491 ATP2B1 membrane 1 mitogen- activated protein kinase 7156 0,0453526 0,3465139 161,8 329,6 0,491 MAP2K3 kinase 3 RAS guanyl releasing protein 2 (calcium and DAG- 2202 0,0057806 0,1435306 15,1 30,8 0,49 RASGRP2 regulated) Casein kinase 4288 0,0185511 0,2365395 57 116,4 0,49 CSNK1A1 1, alpha 1 Eukaryotic translation initiation factor 4505 0,0202853 0,2460654 49,7 101,5 0,49 EIF1 1 chromodomain helicase DNA binding protein 364 0,0003822 0,0572515 233,1 477,2 0,488 CHD1 1 leucine rich repeat 1952 0,0046469 0,1301584 39,9 81,8 0,488 LRRC32 containing 32 RAB11 family interacting protein 1 (class 3583 0,0133864 0,2042456 167,5 343,4 0,488 RAB11FIP1 I) leukotriene B4 12- hydroxydehydr 6242 0,0359042 0,3144925 67 137,3 0,488 LTB4DH ogenase gamma- glutamyltransfe 2292 0,0062426 0,1488791 36,2 74,4 0,487 GGT1 rase 1 hypothetical gene supported by 2793 0,0089078 0,1743766 21 43,1 0,487 LOC439911 NM_194304 chloride intracellular 4764 0,0223124 0,2560628 195,1 400,5 0,487 CLIC2 channel 2

1841 0,0042248 0,1254704 200,2 412,2 0,486 TUBA1 tubulin, alpha 1 Proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 3124 0,0107455 0,1880463 54,3 111,7 0,486 PSMD7 homolog) pyrimidinergic receptor P2Y, G-protein 4754 0,0222529 0,2559271 21,9 45,1 0,486 P2RY6 coupled, 6 Forkhead box 4798 0,0226397 0,257834 56,9 117,1 0,486 FOXO3A O3A SKI-like 3357 0,0121675 0,1981221 81,4 167,9 0,485 SKIL oncogene nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 3608 0,0134957 0,2043749 141,8 292,6 0,485 NFKB1 (p105) jun D proto- 276 0,0002686 0,0525339 1427,3 2949,6 0,484 JUND oncogene v-rel reticuloendoth eliosis viral oncogene homolog 2405 0,0067969 0,15452 17,7 36,6 0,484 REL (avian) junction- mediating and regulatory 3542 0,0131289 0,2026324 7,7 15,9 0,484 JMY protein NudE nuclear distribution gene E homolog 1 (A. 4866 0,02316 0,2599793 104,7 216,4 0,484 NDE1 nidulans) 4885 0,0233213 0,2609998 41,4 85,5 0,484 TPM3 tropomyosin 3 v-src sarcoma (Schmidt- Ruppin A-2) viral oncogene homolog 5934 0,0326034 0,3004029 102,9 212,8 0,484 SRC (avian) similar to Adenylate kinase isoenzyme 4, mitochondrial (ATP-AMP transphosphor ylase) /// similar to Adenylate kinase isoenzyme 4, mitochondrial (Adenylate kinase 3-like 1) LOC645619 (ATP-AMP /// transphosphor 634 0,0007729 0,0666535 45,5 94,2 0,483 LOC731007 ylase) ADAMTS-like 3120 0,0107211 0,187877 79,2 164 0,483 ADAMTSL4 4

Myeloid cell leukemia sequence 1 84 5,54E-05 0,0360595 41,5 86,1 0,482 MCL1 (BCL2-related) Period homolog 1 5004 0,0243227 0,2657561 19 39,4 0,482 PER1 (Drosophila) complement component 3a 5245 0,0264397 0,2755518 105,6 218,9 0,482 C3AR1 receptor 1 inhibitor of DNA binding 1, dominant negative helix- loop-helix 7426 0,0483915 0,3562249 6,6 13,7 0,482 ID1 protein Phosphoglycer ate dehydrogenas 3903 0,0156084 0,2186258 11,6 24,1 0,481 PHGDHL1 e like 1 ubiquitin specific 4867 0,0231601 0,2599793 17,7 36,8 0,481 USP12 peptidase 12 RAS guanyl releasing protein 2 (calcium and DAG- 5289 0,0268066 0,27707 11,1 23,1 0,481 RASGRP2 regulated)

chromosome 6 open reading 492 0,0005634 0,0624087 24,6 51,3 0,48 C6orf150 frame 150 epithelial membrane 773 0,0010646 0,075254 825,2 1718,8 0,48 EMP3 protein 3 7257 0,046677 0,3516011 75,8 158,1 0,479 NRP1 Neuropilin 1 syntaxin binding protein 660 0,0008377 0,0693761 13 27,2 0,478 STXBP3 3 VENT homeobox homolog (Xenopus 1196 0,0021235 0,0970402 31,1 65 0,478 VENTX laevis)

major histocompatibili ty complex, class II, DQ beta 1 /// major histocompatibil ity complex, class II, DQ 1328 0,0025183 0,1035459 496,2 1037,6 0,478 HLA-DQB1 beta 1 jun D proto- 3561 0,0132693 0,2036605 21,6 45,2 0,478 JUND oncogene

CDNA FLJ31718 fis, clone 3889 0,0155015 0,2179338 204,6 428 0,478 NA NT2RI2006647

jumonji domain 5344 0,0273073 0,2793774 28,1 58,8 0,478 JMJD3 containing 3 MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer 2231 0,0059029 0,1446021 55,6 116,6 0,477 MEF2A factor 2A) chromosome 18 open reading frame 2498 0,0073051 0,1597509 29 60,8 0,477 C18orf1 1 nucleoporin 2571 0,0077465 0,1647374 150,9 316,1 0,477 NUP50 50kDa tubulin, beta 3297 0,0117681 0,1951534 238,6 500 0,477 TUBB2A 2A DENN/MADD domain 4622 0,0212147 0,2509234 89,4 187,4 0,477 DENND4A containing 4A LATS, large tumor suppressor, homolog 2 1674 0,0035984 0,1175284 255,4 536 0,476 LATS2 (Drosophila) MYC associated 7551 0,0497476 0,3600842 17,2 36,1 0,476 MAX factor X SLAM family 117 8,27E-05 0,0386463 182,9 385 0,475 SLAMF9 member 9 NLR family, pyrin domain 579 0,0006972 0,0657513 17,1 36 0,475 NLRP1 containing 1 runt-related transcription 657 0,0008318 0,0691996 93,6 197,2 0,475 RUNX2 factor 2 transmembran e, prostate androgen 1204 0,0021468 0,0974395 7,7 16,2 0,475 TMEPAI induced RNA tumor protein p53 inducible nuclear protein 1983 0,0048047 0,1324745 80,3 169,2 0,475 TP53INP2 2 hypothetical protein 2372 0,0066311 0,1528204 123,4 259,6 0,475 LOC283680 LOC283680 UBX domain 829 0,0011903 0,0785038 169,8 358,1 0,474 UBXD7 containing 7

adenylate 1365 0,0025983 0,1040748 86,5 182,5 0,474 AK3L1 kinase 3-like 1 Guanine nucleotide binding protein (G protein), beta 6520 0,0384573 0,3224735 18,8 39,7 0,474 GNB1 polypeptide 1 coiled-coil domain 421 0,0004476 0,0577884 52,7 111,3 0,473 CCDC49 containing 49 ATP-binding cassette, sub- family G (WHITE), 2241 0,0059837 0,1459879 8,8 18,6 0,473 ABCG1 member 1

cystatin F 5920 0,0325168 0,3003135 36,1 76,3 0,473 CST7 (leukocystatin)

adenylate 402 0,0004313 0,0577884 129,1 273,4 0,472 AK3L1 kinase 3-like 1 forkhead box 921 0,0013738 0,0815554 57,5 121,7 0,472 FOXO3A O3A

insulin-like growth factor 2 mRNA binding 989 0,0015522 0,0856868 5,8 12,3 0,472 IGF2BP3 protein 3 pyruvate dehydrogenas e kinase, 1445 0,0028523 0,107898 71,5 151,5 0,472 PDK1 isozyme 1

zinc finger CCCH-type 6673 0,0402106 0,3294642 67,3 142,6 0,472 ZC3H12A containing 12A Zinc finger 7103 0,0448619 0,3453183 21,2 44,9 0,472 ZNF395 protein 395 transducin-like enhancer of split 4 (E(sp1) homolog, 87 6,04E-05 0,0367348 252,3 535,2 0,471 TLE4 Drosophila) 437 0,0004667 0,0583909 24,8 52,6 0,471 NA NA hypothetical protein 1099 0,001853 0,0921338 46,8 99,4 0,471 LOC286052 LOC286052 kelch repeat and BTB (POZ) domain 2861 0,0092238 0,176217 51,4 109,2 0,471 KBTBD2 containing 2

endothelial cell growth factor 1 (platelet- 3370 0,0122273 0,1983671 126,1 267,7 0,471 ECGF1 derived)

Leucine rich repeat (in FLII) interacting 5833 0,0316068 0,296263 39,5 83,8 0,471 LRRFIP2 protein 2 tensin 1 /// 1044 0,0016896 0,088241 63,9 136 0,47 TNS1 tensin 1 Ring finger and FYVE-like domain 1917 0,0045386 0,1293549 7,1 15,1 0,47 RFFL containing 1 cytidine 4134 0,0173388 0,22922 115,2 245,1 0,47 CDA deaminase

cylindromatosi s (turban tumor 5932 0,0325931 0,3003688 8,5 18,1 0,47 CYLD syndrome) Rho GTPase activating 277 0,0002688 0,0525339 62,4 133,2 0,468 ARHGAP27 protein 27 chromosome 10 open reading frame 391 0,0004144 0,0577756 79,2 169,1 0,468 C10orf54 54

colony stimulating factor 2 receptor, beta, low-affinity (granulocyte- macrophage) /// colony stimulating factor 2 receptor, beta, low-affinity (granulocyte- 1362 0,0025958 0,1040748 321,2 686 0,468 CSF2RB macrophage) heterochromati n protein 1, binding protein 1935 0,0045826 0,1294851 28,1 60 0,468 HP1BP3 3 mitogen- activated protein kinase kinase kinase 4088 0,0170357 0,2277978 64,6 137,9 0,468 MAP3K8 8 Membrane associated DNA binding 2999 0,0100157 0,1825536 22,4 48 0,467 MNAB protein

nuclear RNA 3355 0,0121646 0,1981221 208,7 446,6 0,467 NXF1 export factor 1 KIAA1466 1566 0,0032647 0,1138946 33,1 71,1 0,466 KIAA1466 gene

CDC42 effector protein (Rho GTPase 4874 0,0231778 0,2599793 43,2 92,7 0,466 CDC42EP4 binding) 4 Hypothetical 6419 0,0375382 0,3197384 15,6 33,5 0,466 CG018 gene CG018 jun D proto- 6719 0,0408492 0,3323697 22,7 48,7 0,466 JUND oncogene period homolog 2 3419 0,0124093 0,1984223 159,7 344,4 0,464 PER2 (Drosophila) ATPase, H+ transporting, lysosomal 50/57kDa, V1 4824 0,0228175 0,2586088 48,8 105,2 0,464 ATP6V1H subunit H Thyroid hormone receptor associated 7132 0,0451972 0,3464592 28 60,3 0,464 THRAP2 protein 2 249 0,0002328 0,0511178 31,8 68,8 0,462 NA NA spermidine/spe rmine N1- acetyltransfera 1377 0,0026448 0,1048471 1398,3 3024,9 0,462 SAT1 se 1 CD109 3267 0,011575 0,1936505 93,5 202,4 0,462 CD109 molecule v-ral simian leukemia viral oncogene homolog A (ras 4877 0,0232161 0,2602707 271,5 587,1 0,462 RALA related) Transcribed 6813 0,0418346 0,3357268 62,8 135,9 0,462 NA locus

2@#$%&- 5@#$%&- oligoadenylate 7201 0,045982 0,3491273 31,7 68,6 0,462 OASL synthetase-like forkhead box 102 7,22E-05 0,0382725 107,2 232,4 0,461 FOXO3A O3A intercellular adhesion molecule 1 (CD54), human rhinovirus 1009 0,0015955 0,0864559 164,6 357 0,461 ICAM1 receptor ankyrin repeat 2510 0,0073541 0,1601934 127 275,6 0,461 ANKRD10 domain 10 ankyrin repeat 4818 0,0227229 0,2578611 10,5 22,8 0,461 ANKRD28 domain 28 allograft inflammatory 1558 0,0032519 0,1138946 740,7 1611,5 0,46 AIF1 factor 1 related RAS viral (r-ras) oncogene 2652 0,0081608 0,1681297 83,3 180,9 0,46 RRAS homolog prostaglandin E receptor 4 4013 0,0164785 0,2245012 236,1 513,2 0,46 PTGER4 (subtype EP4) Proteasome (prosome, macropain) subunit, beta 5565 0,0292728 0,2875993 59 128,4 0,46 PSMB7 type, 7 ras homolog gene family, 1131 0,0019542 0,0944703 23,3 50,8 0,459 RHOU member U interferon regulatory 1337 0,002541 0,1036037 57,4 125 0,459 IRF7 factor 7 sialic acid binding Ig-like lectin 1, 1421 0,0027738 0,1067259 20,2 44 0,459 SIGLEC1 sialoadhesin allograft inflammatory 1644 0,003495 0,1161645 790,3 1722,4 0,459 AIF1 factor 1

interferon, alpha-inducible 2310 0,0063314 0,149757 58,3 127,1 0,459 IFI6 protein 6 candidate tumor suppressor in ovarian cancer 5310 0,0269918 0,2779108 35,6 77,6 0,459 OVCA2 2 6804 0,0417702 0,3356534 86,1 188,1 0,458 F11R F11 receptor deoxynucleotid yltransferase, terminal, interacting 1482 0,0029707 0,1095772 400,2 875,1 0,457 DNTTIP2 protein 2 CDNA FLJ35556 fis, clone SPLEN200484 3693 0,0140092 0,2073717 73,4 160,6 0,457 NA 4 interleukin 1 receptor accessory 3855 0,0152872 0,2168165 10,8 23,7 0,456 IL1RAP protein ets variant gene 5 (ets- related 7164 0,0455769 0,3477164 50,1 109,9 0,456 ETV5 molecule)

runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 808 0,0011292 0,0763495 31,2 68,5 0,455 RUNX1 oncogene)

integrin, alpha 5 (fibronectin receptor, alpha 2948 0,0096917 0,1796896 328,9 723,2 0,455 ITGA5 polypeptide) additional sex combs like 1 4277 0,0184355 0,2356701 50,1 110,2 0,455 ASXL1 (Drosophila) hypothetical protein 5802 0,0313174 0,2950284 65,7 144,4 0,455 LOC129607 LOC129607

signal transducer and activator of 6315 0,0366432 0,3172553 21,2 46,6 0,455 STAT4 transcription 4

retinoid X 670 0,0008543 0,0697147 64,4 141,9 0,454 RXRA receptor, alpha 2021 0,005001 0,1352942 61,6 135,6 0,454 NA NA FOS-like 621 0,0007482 0,0658741 220,5 486,7 0,453 FOSL2 antigen 2 MAX dimerization 1129 0,0019509 0,0944329 139,8 308,6 0,453 MXD1 protein 1

Vesicle transport through interaction with t-SNAREs homolog 1A 1886 0,0044207 0,1280965 15,3 33,8 0,453 VTI1A (yeast)

3720 0,0141713 0,2082838 42,9 95 0,452 CD80 CD80 molecule 5898 0,0322788 0,2991878 98,3 217,5 0,452 NA NA 7076 0,0445685 0,3443729 15,1 33,4 0,452 TUFT1 tuftelin 1 proline-rich nuclear receptor 412 0,0004401 0,0577884 631,6 1399,2 0,451 PNRC1 coactivator 1 toll-like receptor adaptor 3504 0,0129639 0,2021636 46,8 103,7 0,451 TICAM1 molecule 1 rearranged L- 1720 0,0037638 0,1195727 95,5 212,3 0,45 RLF myc fusion Splicing factor proline/glutami ne-rich (polypyrimidine tract binding protein 5222 0,0262798 0,2749963 14 31,1 0,45 SFPQ associated) Beta-2- 2001 0,0048875 0,1334529 63,7 141,8 0,449 B2M microglobulin

Clone TESTIS- 724 mRNA 2733 0,0085839 0,1716407 141,1 314,5 0,449 NA sequence CD44 molecule (Indian blood 3145 0,010908 0,1895776 64,9 144,5 0,449 CD44 group) Elongation factor, RNA polymerase II, 4814 0,0227041 0,257834 56,9 126,7 0,449 ELL2 2 Transcribed 5972 0,0329938 0,3020656 70,6 157,4 0,449 NA locus

Full-length cDNA clone CS0DD001YA 12 of Neuroblastoma Cot 50- normalized of Homo sapiens 1187 0,0021034 0,096818 172,7 385,5 0,448 NA (human) ADP- ribosylation 2412 0,0068567 0,1553951 206,6 461,4 0,448 ARF6 factor 6 DENN/MADD domain 3551 0,0131826 0,2029454 18,9 42,2 0,448 DENND3 containing 3 cryptochrome 1 (photolyase- 5427 0,0280967 0,2828411 103,1 230,3 0,448 CRY1 like) mitogen- activated protein kinase kinase 3 /// mitogen- activated protein kinase 6235 0,0358614 0,314447 254,3 567,6 0,448 MAP2K3 kinase 3 immediate early response 532 0,0006268 0,0635709 903,2 2020,3 0,447 IER5 5 extra spindle pole bodies homolog 1 (S. 1150 0,0019968 0,0949348 30,3 67,8 0,447 ESPL1 cerevisiae) acetylserotonin O- methyltransfer 4016 0,0165013 0,2246535 63,9 143 0,447 ASMTL ase-like Myeloid cell leukemia sequence 1 1626 0,0034627 0,1161645 111,8 250,6 0,446 MCL1 (BCL2-related)

A kinase (PRKA) anchor protein 13 /// A kinase (PRKA) anchor protein 4589 0,0209221 0,2492097 528 1184,2 0,446 AKAP13 13 6057 0,0339344 0,3062856 12 26,9 0,446 NA NA

chromosome 9 open reading 221 0,0001964 0,0483249 10,2 22,9 0,445 C9orf164 frame 164 allograft inflammatory 1650 0,0035083 0,1161645 727,2 1634,8 0,445 AIF1 factor 1 inhibitor of growth family, 2520 0,0074203 0,160994 102,8 230,9 0,445 ING3 member 3 Janus kinase 1 (a protein tyrosine 5595 0,0294851 0,2881319 33,3 74,9 0,445 JAK1 kinase) N-myc downstream regulated gene 7342 0,0475757 0,354238 18,1 40,7 0,445 NDRG1 1 v-maf musculoapone urotic fibrosarcoma oncogene homolog 115 8,10E-05 0,0382725 16,5 37,2 0,444 MAF (avian) Transcribed 2427 0,0069119 0,1555897 26,7 60,1 0,444 NA locus potassium intermediate/s mall conductance calcium- activated channel, subfamily N, 2636 0,0080789 0,167497 157 353,6 0,444 KCNN4 member 4 acetylserotonin O- methyltransfer 3582 0,0133848 0,2042456 46 103,5 0,444 ASMTL ase-like solute carrier family 25, 5355 0,0273683 0,2794089 46 103,5 0,444 SLC25A37 member 37 ankylosis, progressive homolog 4710 0,0219024 0,2542492 31,3 70,7 0,443 ANKH (mouse) EH-domain 3364 0,0121899 0,1981221 87,3 197,7 0,442 EHD1 containing 1 casein kinase 3890 0,0155117 0,2180044 34 76,9 0,442 CSNK1E 1, epsilon chromosome 15 open reading frame 3629 0,0136357 0,2052986 12,8 29 0,441 C15orf39 39 Active BCR- 4506 0,0202893 0,2460654 14,2 32,2 0,441 ABR related gene mitogen- activated protein kinase kinase kinase 1536 0,0031789 0,1131552 137,3 312,1 0,44 MAP3K4 4

nuclear factor of activated T- cells 5, tonicity- 4369 0,0191952 0,2402134 125,5 285,6 0,439 NFAT5 responsive NLR family, pyrin domain 4963 0,0239392 0,2636956 16,9 38,5 0,439 NLRP1 containing 1

Chromosome 1 open reading 5037 0,0246236 0,2672812 15,5 35,3 0,439 C1orf58 frame 58 splicing factor proline/glutami ne-rich (polypyrimidine tract binding protein 6498 0,0383093 0,322196 84,7 193,3 0,438 SFPQ associated) major histocompatibili ty complex, class II, DP 6871 0,0423346 0,3368398 332,2 758,7 0,438 HLA-DPA1 alpha 1 Secreted phosphoprotei n 1 (osteopontin, bone sialoprotein I, early T- lymphocyte 7514 0,0493517 0,3591036 19,9 45,4 0,438 SPP1 activation 1) hypothetical gene supported by 334 0,0003396 0,0552439 75,1 171,7 0,437 LOC401805 NM_144726

Notch homolog 1, translocation- associated 1207 0,0021523 0,0974517 67,5 154,5 0,437 NOTCH1 (Drosophila) Sp3 transcription 2096 0,0053228 0,138789 136,6 312,9 0,437 SP3 factor

2@#$%&- 5@#$%&- oligoadenylate 5630 0,02981 0,2894775 17,4 39,8 0,437 OASL synthetase-like dual specificity phosphatase 6269 0,0361759 0,3155076 34 77,8 0,437 DUSP10 10

solute carrier family 6 (neurotransmitt er transporter, taurine), member 6 /// solute carrier family 6 (neurotransmitt er transporter, taurine), 6845 0,0421613 0,3366308 29,3 67 0,437 SLC6A6 member 6 forkhead box 488 0,0005525 0,0619015 229,6 526,8 0,436 FOXO3A O3A Hypothetical protein 2769 0,0087832 0,1732398 5,8 13,3 0,436 LOC729436 LOC729436 CDNA FLJ41489 fis, clone BRTHA200458 4789 0,0225536 0,2574897 7,8 17,9 0,436 NA 2 RAB18, member RAS oncogene 5979 0,03311 0,3027746 65,6 150,5 0,436 RAB18 family

cytochrome P450, family 1, subfamily B, 2311 0,0063334 0,149757 105,5 243,1 0,434 CYP1B1 polypeptide 1 v-rel reticuloendoth eliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 2379 0,0066555 0,1529316 34,6 79,7 0,434 RELB (avian) procollagen- proline, 2- oxoglutarate 4- dioxygenase (proline 4- hydroxylase), alpha 3936 0,0158335 0,2199432 47 108,2 0,434 P4HA2 polypeptide II phospholipid 4116 0,0172354 0,2288456 147,1 339 0,434 PLSCR1 scramblase 1 ATPase, Class I, type 8B, 7318 0,0472824 0,3532612 8,6 19,8 0,434 ATP8B2 member 2 patatin-like phospholipase domain 4685 0,0217049 0,253301 405,9 936,4 0,433 PNPLA8 containing 8 DnaJ (Hsp40) homolog, subfamily B, member 6 /// similar to DnaJ (Hsp40) homolog, subfamily B, DNAJB6 /// member 6 1785 0,004006 0,1227048 249,1 576,3 0,432 LOC387820 isoform a mannosyl (alpha-1,3-)- glycoprotein beta-1,4-N- acetylglucosa minyltransferas 4831 0,022867 0,2587784 33,4 77,4 0,432 MGAT4A e, isozyme A Ubiquitin- conjugating enzyme E2H (UBC8 homolog, 4964 0,0239412 0,2636956 15,2 35,2 0,432 UBE2H yeast)

runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 370 0,0003926 0,0577756 36,2 83,9 0,431 RUNX1 oncogene) neuroepithelial cell transforming 500 0,0005741 0,0626634 75,5 175,3 0,431 NET1 gene 1 B-cell translocation gene 1, anti- 1634 0,0034787 0,1161645 828,8 1924,3 0,431 BTG1 proliferative hypothetical gene supported by 2325 0,00638 0,1498086 8,1 18,8 0,431 LOC400043 BC009385 MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer 2945 0,0096888 0,1796896 265,4 615,8 0,431 MEF2A factor 2A) ST8 alpha-N- acetyl- neuraminide alpha-2,8- sialyltransferas 3263 0,0115693 0,1936505 7,2 16,7 0,431 ST8SIA4 e 4 S-phase kinase- associated protein 1A 181 0,0001624 0,0481428 65,3 151,9 0,43 SKP1A (p19A)

ribosomal protein S6 kinase, 90kDa, 5510 0,0288408 0,2861008 51,8 120,4 0,43 RPS6KA5 polypeptide 5

LILRB2 /// LILRA6 /// 1036 0,0016674 0,0879972 102 237,8 0,429 LOC652626 NA caspase-1 dominant- negative inhibitor 2545 0,0075862 0,1628925 145,2 338,7 0,429 COP1 pseudo-ICE intercellular adhesion 100 7,06E-05 0,0382725 97,1 226,7 0,428 ICAM2 molecule 2 Folliculin interacting 1749 0,0038727 0,1210634 7,4 17,3 0,428 FNIP1 protein 1

chromosome 5 open reading 1618 0,0034346 0,116061 94,2 221,2 0,426 C5orf26 frame 26 hypothetical 2820 0,0090402 0,175254 22,4 52,6 0,426 LOC25845 LOC25845 centaurin, beta 4540 0,0205641 0,2476268 26 61 0,426 CENTB1 1 NLR family, pyrin domain 2755 0,0087071 0,1727429 14,2 33,4 0,425 NLRP1 containing 1 Tetratricopepti de repeat 5990 0,0332501 0,3034974 16,5 38,8 0,425 TTC7A domain 7A ubiquitin specific 46 2,66E-05 0,0312927 74,9 176,8 0,424 USP15 peptidase 15 Ubiquitin specific 6763 0,0413417 0,3342241 44,6 105,1 0,424 USP12 peptidase 12

Transmembran 7298 0,0471124 0,3529557 23,7 55,9 0,424 TMEM140 e protein 140

protein kinase C, delta 2858 0,009218 0,176217 22,3 52,7 0,423 PRKCDBP binding protein 4106 0,0171682 0,2285213 27 63,8 0,423 CUL4A Cullin 4A N- acetyltransfera 2942 0,0096784 0,1796896 93,8 222,6 0,421 NAT13 se 13 retinoic acid receptor responder (tazarotene 4816 0,0227154 0,257834 35,5 84,3 0,421 RARRES3 induced) 3 beta-1,3-N- acetylgalactos aminyltransfer ase 1 (globoside 3470 0,0127172 0,2002405 14,8 35,2 0,42 B3GALNT1 blood group)

CD1b molecule /// 5628 0,0298025 0,2894775 231,8 551,8 0,42 CD1B CD1b molecule

vascular endothelial 4421 0,0196372 0,2428215 12,9 30,8 0,419 VEGFA growth factor A nuclear protein 6237 0,0358725 0,3144667 12,2 29,1 0,419 NUPR1 1 7352 0,0476599 0,3544349 81,8 195,1 0,419 ATXN1 Ataxin 1 CDC-like 712 0,0009232 0,0708321 128,4 307,3 0,418 CLK1 kinase 1

Chromosome 7 open reading 982 0,0015254 0,08493 21,3 50,9 0,418 C7orf38 frame 38

inducible T-cell co-stimulator 205 0,0001832 0,0483249 49,5 118,6 0,417 ICOSLG ligand intercellular adhesion molecule 1 (CD54), human rhinovirus 2796 0,0089354 0,1747293 104,5 250,4 0,417 ICAM1 receptor

TSC22 domain family, member 5895 0,0322094 0,298736 19,2 46 0,417 TSC22D3 3 mesoderm development 7422 0,0483645 0,3562249 196,4 470,6 0,417 MESDC1 candidate 1 nuclear factor (erythroid- derived 2)-like 3296 0,0117648 0,1951534 14,2 34,1 0,416 NFE2L3 3

DDEF1 intronic 7310 0,0472034 0,3530333 64,3 154,5 0,416 DDEF1IT1 transcript 1 CD226 481 0,0005439 0,0615795 41,8 100,8 0,415 CD226 molecule fms-related tyrosine kinase 2704 0,0083952 0,1697513 14 33,7 0,415 FLT3 3

CDNA FLJ32866 fis, clone 6982 0,0436479 0,3418002 10,5 25,3 0,415 NA TESTI2003718 280 0,0002696 0,0525339 27,5 66,5 0,414 NA NA FOS-like 1804 0,0040836 0,1237643 58,4 141,1 0,414 FOSL2 antigen 2 Ras association (RalGDS/AF-6) domain family 1170 0,0020613 0,0961653 229,4 555,7 0,413 RASSF5 5 1520 0,0030964 0,1113787 31,7 76,7 0,413 NA NA Sequestosome 4802 0,022652 0,257834 101,9 247 0,413 SQSTM1 1 aryl- hydrocarbon receptor 7386 0,0479725 0,3550265 245,2 593,2 0,413 AHRR repressor death effector domain 2985 0,0099295 0,1818173 205,7 499,5 0,412 DEDD2 containing 2 chromosome 15 open reading frame 45 2,64E-05 0,0312927 41,1 100 0,411 C15orf39 39

Polymerase (DNA directed) 3166 0,011034 0,1905442 22,6 55 0,411 POLS sigma patatin-like phospholipase domain 4408 0,0195311 0,2422309 335,5 815,9 0,411 PNPLA8 containing 8 zinc finger 125 9,93E-05 0,0430138 25,3 61,7 0,41 ZFHX1B homeobox 1b

Integrin, alpha V (vitronectin receptor, alpha polypeptide, 3012 0,0100746 0,1828781 37,7 92 0,41 ITGAV antigen CD51) RAB11 family interacting protein 1 (class 3505 0,0129645 0,2021636 554 1349,9 0,41 RAB11FIP1 I) 1166 0,0020384 0,0955828 10,1 24,7 0,409 CNNM2 cyclin M2 nucleoporin 4301 0,0186375 0,2368636 100,1 245,4 0,408 NUP98 98kDa phosphatidylin ositol glycan anchor biosynthesis, class A (paroxysmal nocturnal hemoglobinuri a) /// phosphatidylin ositol glycan anchor biosynthesis, class A (paroxysmal nocturnal hemoglobinuri 5495 0,0286507 0,2850732 32,9 80,9 0,407 PIGA a) dual specificity phosphatase 5573 0,0293415 0,2878108 82,9 203,8 0,407 DUSP10 10 Chromosome 10 open reading frame 1417 0,0027616 0,1065564 32,1 79 0,406 C10orf76 76 complement 1881 0,0044036 0,1279192 112,5 277 0,406 C2 component 2 zinc finger 4377 0,0192773 0,2407985 44,4 110,3 0,403 ZNF638 protein 638 mitogen- activated protein kinase kinase kinase 5392 0,0276875 0,2807519 20,1 49,9 0,403 MAP4K1 kinase 1 1125 0,001945 0,0944329 29 72,1 0,402 NA NA PDZ and LIM 1597 0,0033712 0,1154166 25,9 64,5 0,402 PDLIM4 domain 4 CDNA FLJ41489 fis, clone BRTHA200458 7542 0,0495986 0,3595603 13,4 33,3 0,402 NA 2 PDZ and LIM 672 0,0008596 0,069812 50,4 125,9 0,4 PDLIM4 domain 4 UDP- Gal:betaGlcNA c beta 1,4- galactosyltrans ferase, 6766 0,0413741 0,3342663 36 90 0,4 B4GALT5 polypeptide 5 thrombomoduli 3207 0,0113299 0,1931276 201,2 504,2 0,399 THBD n cAMP responsive element binding protein 1298 0,0024288 0,1023071 5,5 13,9 0,396 CREB5 5 transducer of 4314 0,0187073 0,2370936 54,7 138,1 0,396 TOB2 ERBB2, 2 linker for activation of T cells family, 961 0,0014808 0,0839343 104,3 264,3 0,395 LAT2 member 2 thyroid hormone receptor associated 2298 0,0062586 0,1489073 35,4 89,6 0,395 THRAP1 protein 1 UDP-N- acteylglucosa mine pyrophosphory 2645 0,0081258 0,167969 96,6 244,4 0,395 UAP1 lase 1 mitogen- activated protein kinase kinase kinase 4437 0,0197456 0,2433155 25,5 64,6 0,395 MAP4K1 kinase 1 ADP- ribosylation 6433 0,037663 0,3201033 112,8 285,8 0,395 ARL4A factor-like 4A Transcribed 902 0,0013269 0,0804304 25,2 64 0,394 NA locus

thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) /// nuclear receptor subfamily 1, THRA /// group D, 7071 0,0445385 0,3443489 14,9 37,8 0,394 NR1D1 member 1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide 1146 0,0019847 0,0946254 24,5 62,4 0,393 NPR1 receptor A)

phosphodieste rase 4B, cAMP- specific (phosphodieste rase E4 dunce homolog, 1214 0,0021707 0,097762 8,3 21,1 0,393 PDE4B Drosophila) cell division cycle 42 (GTP binding protein, 5152 0,0256485 0,2721917 11,8 30 0,393 CDC42 25kDa)

zinc finger and BTB domain 2168 0,0056273 0,1417702 147,2 376,2 0,391 ZBTB43 containing 43 Guanylate binding protein 384 0,0004076 0,0577756 12,1 31,1 0,389 GBP5 5 myeloid leukemia factor 2516 0,0073947 0,1606936 7 18 0,389 MLF1 1 hypothetical protein 7368 0,0478371 0,3547819 24,4 62,7 0,389 LOC389072 LOC389072 zinc finger 23 1,49E-05 0,0302321 141,3 363,8 0,388 ZFHX1B homeobox 1b Kruppel-like 1713 0,0037367 0,1192668 1058,7 2726,8 0,388 KLF6 factor 6 (clone B3B3E13) Huntington@# $%&s disease candidate region mRNA 3123 0,0107428 0,1880463 24,1 62,1 0,388 NA fragment

Chromosome 3 open reading 5295 0,0268434 0,277179 48 123,7 0,388 C3orf1 frame 1 chemokine (C- C motif) ligand 369 0,0003891 0,0576532 2161,8 5583,6 0,387 CCL13 13 5170 0,0257688 0,2723069 92,9 239,9 0,387 NA NA v-maf musculoapone urotic fibrosarcoma oncogene homolog 1161 0,002024 0,0953163 616,5 1598,2 0,386 MAF (avian)

insulin-like growth factor 2 mRNA binding 1492 0,0029902 0,1095772 5,9 15,3 0,386 IGF2BP3 protein 3 achaete-scute complex homolog 2 5043 0,0246614 0,267373 44,7 115,7 0,386 ASCL2 (Drosophila)

spen homolog, transcriptional regulator 8 6,70E-06 0,0302321 206,6 538,2 0,384 SPEN (Drosophila) Pyruvate dehydrogenas e kinase, 231 0,0002073 0,0487168 40 104,1 0,384 PDK1 isozyme 1 Ets variant gene 5 (ets- related 6380 0,0371447 0,3182155 26,4 68,7 0,384 ETV5 molecule) Response gene to complement 506 0,0005822 0,0628117 18,2 47,5 0,383 RGC32 32 B-cell translocation gene 1, anti- 1122 0,0019407 0,0944329 1132,9 2960 0,383 BTG1 proliferative PR domain containing 1, with ZNF 1182 0,0020815 0,0961653 45,3 118,2 0,383 PRDM1 domain fascin homolog 1, actin- bundling protein (Strongylocentr otus 1392 0,0026779 0,1051826 29 75,8 0,383 FSCN1 purpuratus) inhibitor of DNA binding 2, dominant negative helix- loop-helix protein /// inhibitor of DNA binding 2B, dominant negative helix- loop-helix 4416 0,019602 0,2426946 92,7 242,3 0,383 ID2 /// ID2B protein

zinc finger and BTB domain 1303 0,0024529 0,1029258 171,1 448 0,382 ZBTB43 containing 43

immunoglobuli n superfamily, 4733 0,0220698 0,2549475 13,1 34,3 0,382 IGSF2 member 2 CD44 molecule (Indian blood 5519 0,0288823 0,2861279 253,2 663,2 0,382 CD44 group) PR domain containing 1, with ZNF 471 0,0005193 0,0602236 53,4 140,4 0,38 PRDM1 domain piggyBac transposable element 847 0,0012301 0,0791194 16,5 43,4 0,38 PGBD3 derived 3 mitogen- activated protein kinase kinase kinase 854 0,0012391 0,0791194 272,9 718,8 0,38 MAP3K4 4 solute carrier family 25, 1138 0,0019731 0,0946254 18,2 47,9 0,38 SLC25A37 member 37 CD44 molecule (Indian blood 5379 0,0275819 0,2802874 14,4 37,9 0,38 CD44 group) KIAA0999 4747 0,0221815 0,2554021 59,1 156,1 0,379 KIAA0999 protein serine/threonin e kinase 17b (apoptosis- 6889 0,0424885 0,3372128 98,3 259,1 0,379 STK17B inducing) spermidine/spe rmine N1- acetyltransfera 365 0,0003822 0,0572515 864,4 2293,2 0,377 SAT1 se 1 ATPase, Ca++ transporting, plasma 31 1,80E-05 0,0302321 245 652,3 0,376 ATP2B1 membrane 1 protein regulator of 2831 0,0090888 0,1754434 7,4 19,7 0,376 PRC1 cytokinesis 1 polycomb group ring 2389 0,0067232 0,153734 20,3 54,2 0,375 PCGF2 finger 2

endothelial cell growth factor 1 (platelet- 913 0,0013549 0,0810038 15 40,1 0,374 ECGF1 derived) 448 0,0004902 0,0595242 30,3 81,4 0,372 NA NA

insulin-like growth factor binding protein 435 0,0004664 0,0583909 7,4 20 0,37 IGFBP2 2, 36kDa CUB domain containing 561 0,0006584 0,064104 43 116,3 0,37 CDCP1 protein 1

A kinase (PRKA) anchor 1638 0,0034826 0,1161645 85,1 230,3 0,37 AKAP13 protein 13 thioredoxin interacting 1683 0,0036341 0,1177064 872,5 2358,3 0,37 TXNIP protein

dual specificity 4655 0,0214633 0,2520487 129 348,2 0,37 DUSP5 phosphatase 5 aldolase C, fructose- 2107 0,0053698 0,1392684 38,3 103,8 0,369 ALDOC bisphosphate mitogen- activated protein kinase kinase 3 /// mitogen- activated protein kinase 3859 0,0153239 0,2171117 89,1 241,3 0,369 MAP2K3 kinase 3

response gene to complement 4163 0,0175738 0,2307957 1633,8 4426,7 0,369 RGC32 32 patatin-like phospholipase domain 3177 0,0111491 0,1918717 203 551,3 0,368 PNPLA8 containing 8 macrophage expressed 4175 0,0176747 0,23143 63,5 172,7 0,368 MPEG1 gene 1 adenosine monophosphat e deaminase 5656 0,0301082 0,2910113 59,1 160,7 0,368 AMPD3 (isoform E) vitelline membrane outer layer 1 homolog 538 0,0006303 0,0635709 7,2 19,6 0,367 VMO1 (chicken) ubiquitin specific 5723 0,0306983 0,2932566 38,2 104,1 0,367 USP36 peptidase 36 heme oxygenase 5775 0,0311106 0,2945115 912,1 2484,4 0,367 HMOX1 (decycling) 1 Trichorhinopha langeal 314 0,0003118 0,0541231 8,7 23,8 0,366 TRPS1 syndrome I

CD74 molecule, major histocompatibil ity complex, class II 4653 0,0214507 0,2520487 155,1 425,5 0,365 CD74 invariant chain Kruppel-like 1787 0,0040164 0,1228857 104,4 286,8 0,364 KLF9 factor 9 sorting nexin 2288 0,0062162 0,1485449 187 513,4 0,364 SNX10 10 chemokine-like 2768 0,0087802 0,1732398 11,1 30,5 0,364 CMKLR1 receptor 1 endoplasmic reticulum to nucleus 5582 0,0294192 0,2880914 32,2 88,6 0,363 ERN1 signalling 1 Fc fragment of IgA, receptor 5691 0,0303698 0,2916051 10,5 28,9 0,363 FCAR for

transducin-like enhancer of split 4 (E(sp1) homolog, 298 0,0002901 0,0532256 38 104,9 0,362 TLE4 Drosophila) 559 0,0006563 0,064104 30,9 85,4 0,362 CUL1 Cullin 1

vascular endothelial 1100 0,001854 0,0921338 141,2 389,7 0,362 VEGFA growth factor A nuclear receptor subfamily 1, group D, 5939 0,0326662 0,3006775 207,1 572,8 0,362 NR1D2 member 2 736 0,0009711 0,0720258 11,4 31,6 0,361 NA NA

runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 746 0,0009953 0,0729195 14,3 39,6 0,361 RUNX1 oncogene) retinoblastoma binding protein 4551 0,0206182 0,2476563 9,9 27,4 0,361 RBBP6 6 nuclear receptor subfamily 1, group D, 4893 0,0234034 0,2614647 50,8 140,8 0,361 NR1D2 member 2 ribonuclease, RNase A family, k6 /// ribonuclease, RNase A 6321 0,0367187 0,3175673 684,1 1895,3 0,361 RNASE6 family, k6 macrophage expressed 4724 0,0220074 0,2546853 69,1 191,9 0,36 MPEG1 gene 1

guanylate binding protein 2, interferon- 3366 0,0122072 0,1982671 63,2 176,2 0,359 GBP2 inducible Transcribed 5241 0,0264264 0,2755518 46,6 129,9 0,359 NA locus 6281 0,0362819 0,3158276 210,5 586,6 0,359 JUN jun oncogene Forkhead box 7260 0,0466991 0,3516885 13,4 37,3 0,359 FOXO3A O3A growth arrest and DNA- damage- inducible, 247 0,0002306 0,0510448 23,1 64,5 0,358 GADD45G gamma exostoses 2125 0,0054452 0,1401018 16,7 46,7 0,358 EXT1 (multiple) 1

Fc fragment of IgG, low affinity IIIb, receptor 3920 0,0157191 0,2191822 17,3 48,3 0,358 FCGR3B (CD16b)

nerve growth factor receptor (TNFRSF16) associated 4698 0,0218204 0,2539443 65,8 183,9 0,358 NGFRAP1 protein 1 myeloid- associated differentiation 3132 0,010812 0,188744 92,7 259,6 0,357 MYADM marker arrestin domain 7292 0,0470603 0,3528554 78,3 219,2 0,357 ARRDC3 containing 3 787 0,0010895 0,0756026 52,7 148,2 0,356 NA NA N-myc downstream regulated gene 1818 0,0041286 0,1241646 226,2 635,2 0,356 NDRG1 1

RasGEF domain family, 2503 0,0073182 0,1597509 20,1 56,5 0,356 RASGEF1B member 1B ATPase type 4276 0,0184135 0,2354439 155,1 435,9 0,356 ATP13A3 13A3 DNA-damage- inducible 4353 0,0190675 0,2394936 32,4 91,1 0,356 DDIT4 transcript 4 Zinc finger 5045 0,0246863 0,2675066 243,2 682,6 0,356 ZFHX1B homeobox 1b chromosome 20 open reading frame 11 8,10E-06 0,0302321 25,2 71 0,355 C20orf55 55 6005 0,0334345 0,3043214 15,3 43,1 0,355 EREG Epiregulin WD repeat 726 0,0009476 0,0713031 9,5 26,8 0,354 WDR37 domain 37 solute carrier family 44, 850 0,0012347 0,0791194 311,6 881,3 0,354 SLC44A1 member 1 EH-domain 4675 0,0216532 0,2532382 40,7 115,1 0,354 EHD1 containing 1 hypothetical protein 2667 0,0082365 0,1688529 65 184,1 0,353 LOC284454 LOC284454 2762 0,0087512 0,1732311 84,6 239,7 0,353 NA NA zinc finger 347 0,0003517 0,0554134 35 99,5 0,352 ZNF395 protein 395 hypothetical protein 2876 0,0092798 0,1764162 14,8 42,1 0,352 LOC154761 LOC154761 hypothetical protein 3958 0,0159923 0,2208876 216,2 616,6 0,351 MGC5618 MGC5618 Tensin 1 /// 171 0,0001496 0,0478326 26,6 76,1 0,35 TNS1 Tensin 1 solute carrier family 44, 651 0,0008218 0,0689926 97,9 279,7 0,35 SLC44A1 member 1 Kruppel-like 1156 0,0020111 0,0950722 639,4 1828,3 0,35 KLF6 factor 6 solute carrier family 44, 1368 0,0026263 0,1048471 70,5 201,2 0,35 SLC44A1 member 1 transmembran 1776 0,0039763 0,1224123 138,7 396,4 0,35 TMEM71 e protein 71 WD repeat 1290 0,0024058 0,1019668 59 169 0,349 WDR54 domain 54 C-type lectin domain family 7293 0,0470748 0,3528789 4,8 13,8 0,348 CLEC5A 5, member A kinesin family 3234 0,0114476 0,1934716 69,1 199 0,347 KIF1B member 1B

phosphodieste rase 4B, cAMP- specific (phosphodieste rase E4 dunce homolog, 3345 0,0121104 0,1978882 13,7 39,6 0,346 PDE4B Drosophila) 477 0,0005353 0,0613575 94,8 274,9 0,345 ATXN1 ataxin 1 acetylserotonin O- methyltransfer 2264 0,0060936 0,1470941 143,9 416,8 0,345 ASMTL ase-like Mesoderm development 2505 0,0073208 0,1597509 42,1 122,4 0,344 MESDC1 candidate 1 5994 0,0332942 0,3036971 19,9 57,9 0,344 NRP2 neuropilin 2 Transcribed 74 4,91E-05 0,0357118 12,8 37,3 0,343 NA locus zinc finger CCCH-type, 1327 0,0025171 0,1035459 16,4 47,8 0,343 ZC3HAV1 antiviral 1 solute carrier family 11 (proton- coupled divalent metal ion transporters), 3833 0,0150743 0,2150241 41,6 121,4 0,343 SLC11A1 member 1

CD93 molecule /// 4213 0,0179702 0,2332117 51,4 149,9 0,343 CD93 CD93 molecule zinc finger protein 36, C3H type, homolog 601 0,0007251 0,0657513 249 727,6 0,342 ZFP36 (mouse) S100 calcium binding protein 3570 0,0133175 0,203925 204,4 597 0,342 S100A10 A10 gamma- glutamyltransfe rase-like 5041 0,0246534 0,267373 21,4 62,6 0,342 GGTLA1 activity 1

male germ cell- associated 6532 0,0385717 0,3228352 6,7 19,6 0,342 MAK kinase Chromosome 18 open reading frame 6957 0,043409 0,3411509 13,7 40,1 0,342 C18orf1 1 neuroepithelial cell transforming 48 2,97E-05 0,0326978 40,7 120,2 0,339 NET1 gene 1 solute carrier family 16, member 6 (monocarboxyli c acid 4210 0,017925 0,2327543 139,4 411,4 0,339 SLC16A6 transporter 7) Zinc finger 5220 0,0262619 0,2749963 251,3 741,3 0,339 ZFHX1B homeobox 1b chromodomain helicase DNA binding protein 1073 0,0017744 0,0903205 44,9 132,7 0,338 CHD2 2 V-set and transmembran e domain 2668 0,0082429 0,1689128 24 71 0,338 VSTM1 containing 1 procollagen C- endopeptidase 5317 0,0270717 0,2783798 7,1 21 0,338 PCOLCE2 enhancer 2 Transcribed 2068 0,0051946 0,1372953 14,9 44,2 0,337 NA locus Ankyrin repeat 2284 0,0062019 0,1484432 46,2 137 0,337 ANKRD12 domain 12 cell division cycle 42 (GTP binding protein, 2543 0,0075756 0,1628516 13,7 40,7 0,337 CDC42 25kDa) EH-domain 2464 0,0070905 0,1572947 84,8 253 0,335 EHD1 containing 1

ATPase, Ca++ transporting, plasma 28 1,69E-05 0,0302321 368,3 1103 0,334 ATP2B1 membrane 1 FOS-like 1283 0,0023675 0,1008909 19,9 59,6 0,334 FOSL1 antigen 1 erythrocyte membrane protein band 1656 0,0035361 0,116749 142,2 426,6 0,333 EPB41L3 4.1-like 3 Kruppel-like 2064 0,0051838 0,1372509 379,4 1140,8 0,333 KLF6 factor 6 solute carrier family 16, member 6 (monocarboxyli c acid 5297 0,0268918 0,2775682 79,2 238,9 0,332 SLC16A6 transporter 7) ankyrin repeat 6231 0,0358296 0,3143637 23,7 71,4 0,332 ANKRD28 domain 28 proline-serine- threonine phosphatase interacting 154 0,000127 0,0449393 169,1 510,6 0,331 PSTPIP2 protein 2 CDNA clone IMAGE:529964 1505 0,0030561 0,1109355 60,2 181,7 0,331 NA 2 dedicator of 5048 0,0247013 0,2675403 8,9 26,9 0,331 DOCK4 cytokinesis 4 hypothetical protein 7012 0,0439289 0,3425289 34,5 104,2 0,331 MGC26963 MGC26963 interferon regulatory 321 0,0003253 0,0549787 78 236,5 0,33 IRF1 factor 1 Tumor necrosis factor (ligand) superfamily, 1511 0,0030703 0,1110329 65 196,8 0,33 TNFSF8 member 8 sema domain, immunoglobuli n domain (Ig), transmembran e domain (TM) and short cytoplasmic domain, (semaphorin) 42 2,53E-05 0,0312927 40,2 123,1 0,327 SEMA4D 4D matrix metallopeptida se 12 (macrophage 4026 0,016608 0,2255021 9,5 29,1 0,326 MMP12 elastase)

pleckstrin homology, Sec7 and coiled-coil domains, binding protein /// pleckstrin homology, Sec7 and coiled-coil domains, 1546 0,0032039 0,1132377 365,8 1125,7 0,325 PSCDBP binding protein zinc finger, AN1-type 7150 0,0453185 0,3464592 213 656,7 0,324 ZFAND2A domain 2A

major histocompatibili ty complex, class II, DQ beta 1 /// major histocompatibil ity complex, class II, DQ 5737 0,0308372 0,2937838 675,4 2090,3 0,323 HLA-DQB1 beta 1 sortilin-related receptor, L(DLR class) A repeats- 6643 0,0397995 0,3275685 136,8 423,8 0,323 SORL1 containing serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, 3223 0,0113969 0,1933371 10,9 33,9 0,322 SERPING1 hereditary) 3830 0,0150615 0,2150098 15 46,6 0,322 NA NA Transmembran 406 0,000434 0,0577884 19 59,2 0,321 TMEM23 e protein 23 epithelial membrane 4206 0,0179152 0,2327543 408,5 1272,4 0,321 EMP1 protein 1 protein phosphatase 1, regulatory (inhibitor) 3154 0,010966 0,190097 189,8 593,3 0,32 PPP1R15A subunit 15A 417 0,0004446 0,0577884 82,9 259,8 0,319 LMNA lamin A/C chemokine (C- X-C motif) 3723 0,0141875 0,2083539 12,3 38,6 0,319 CXCL9 ligand 9 Muscleblind- like 701 0,0009052 0,070427 82,1 258,3 0,318 MBNL1 (Drosophila) Pre-B-cell colony enhancing 2741 0,0086344 0,1722103 13,6 42,8 0,318 PBEF1 factor 1 chemokine (C- X-C motif) 2792 0,0089021 0,1743275 84,3 265,2 0,318 CXCR4 receptor 4 chemokine (C- X-C motif) receptor 4 /// chemokine (C- X-C motif) 2639 0,0080912 0,167497 75,4 238,3 0,316 CXCR4 receptor 4 Pre-B-cell colony enhancing 4674 0,0216404 0,2531427 184 581,6 0,316 PBEF1 factor 1 erythrocyte membrane protein band 907 0,001336 0,0805356 205,9 653,3 0,315 EPB41L3 4.1-like 3 myotubularin related protein 7139 0,045239 0,3464592 22,7 72,3 0,314 MTMR11 11 MARCKS-like 70 4,58E-05 0,0355773 43,4 138,7 0,313 MARCKSL1 1 thyroid hormone receptor 898 0,0013189 0,0802264 23,7 75,7 0,313 TRIP10 interactor 10 complement factor 1254 0,0022622 0,0986109 81 258,7 0,313 CFP properdin thioredoxin interacting 2187 0,0057049 0,1426225 812,9 2617,8 0,311 TXNIP protein

TAF4b RNA polymerase II, TATA box binding protein (TBP)- associated 3476 0,0127366 0,2003376 10,1 32,5 0,311 TAF4B factor, 105kDa solute carrier family 13 (sodium/sulfate symporters), member 4 /// hypothetical SLC13A4 /// protein LOC641845 LOC641845 /// /// hypothetical 215 0,0001919 0,0483249 11,6 37,4 0,31 LOC647087 LOC647087 C-type lectin domain family 1202 0,0021342 0,0970777 319,8 1030,9 0,31 CLEC10A 10, member A solute carrier family 44, 445 0,0004798 0,0589289 271,7 880,1 0,309 SLC44A1 member 1 chromodomain helicase DNA binding protein 751 0,0010061 0,0732456 50,6 163,7 0,309 CHD2 2 adenosine A3 1826 0,0041521 0,1242557 28 90,8 0,308 ADORA3 receptor sema domain, transmembran e domain (TM), and cytoplasmic domain, (semaphorin) 6198 0,0353995 0,3122279 16,8 54,6 0,308 SEMA6B 6B Transcribed 2400 0,006772 0,154244 22,5 73,2 0,307 NA locus DnaJ (Hsp40) homolog, subfamily B, 6460 0,0378932 0,3206717 172,2 561,8 0,307 DNAJB1 member 1 pre-B-cell colony enhancing 199 0,0001805 0,0483249 69,7 227,6 0,306 PBEF1 factor 1 Transcribed 6902 0,0426902 0,3381716 6,6 21,6 0,306 NA locus myristoylated alanine-rich protein kinase 398 0,0004221 0,0577884 267,5 880 0,304 MARCKS C substrate v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson- 816 0,001144 0,0766522 31,5 103,6 0,304 ABL2 related gene) thioredoxin interacting 2100 0,0053324 0,1388328 1075,8 3537,7 0,304 TXNIP protein Transcribed 5821 0,0314658 0,2955493 26,1 85,9 0,304 NA locus erythrocyte membrane protein band 4.1-like 3 /// erythrocyte membrane protein band 304 0,0002999 0,0539376 194 639,8 0,303 EPB41L3 4.1-like 3

zinc finger and BTB domain 846 0,0012298 0,0791194 82,1 271,5 0,302 ZBTB43 containing 43 B-cell CLL/lymphoma 1144 0,0019827 0,0946254 41,2 136,5 0,302 BCL3 3 intercellular adhesion 3467 0,0126953 0,2001833 83,7 276,9 0,302 ICAM3 molecule 3 tissue factor pathway inhibitor (lipoprotein- associated coagulation 5827 0,0315427 0,2959666 7,8 25,8 0,302 TFPI inhibitor) toll-like 193 0,0001708 0,0481929 180,8 601,8 0,3 TLR2 receptor 2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 1547 0,003204 0,1132377 23,7 79 0,3 NFKB2 (p49/p100) major histocompatibili ty complex, class II, DO 7065 0,0445015 0,3442985 30,1 100,3 0,3 HLA-DOA alpha 730 0,0009587 0,071804 80,1 268 0,299 NA NA

signal-induced proliferation- associated 1 1343 0,0025517 0,1036037 52,8 176,7 0,299 SIPA1L1 like 1 5 3,90E-06 0,0302321 16,8 56,4 0,298 NA NA Hypothetical protein 1742 0,0038357 0,1203258 18,5 62,2 0,297 FLJ43663 FLJ43663 Mitogen- activated protein kinase 1282 0,0023674 0,1008909 115,1 388,9 0,296 MAPK10 10 C-type lectin superfamily 4, 1979 0,0047841 0,1321225 61 206,3 0,296 CLEC4G member G MAX dimerization 220 0,000196 0,0483249 88,8 300,7 0,295 MXD1 protein 1 Kruppel-like 336 0,0003415 0,0552439 227,5 771,6 0,295 KLF10 factor 10 2330 0,0063865 0,1498086 266,1 901,3 0,295 LMNA lamin A/C B-cell CLL/lymphoma 3791 0,0147202 0,2122994 24,7 83,7 0,295 BCL10 10 Enhancer of polycomb homolog 1 1737 0,0038147 0,1200741 34,8 118,3 0,294 EPC1 (Drosophila) 865 0,0012579 0,0791194 604 2064,2 0,293 SULF2 sulfatase 2 hypothetical protein 2854 0,0091951 0,1761535 6,9 23,6 0,292 LOC201175 LOC201175 ets variant gene 5 (ets- related 4716 0,0219467 0,2543476 44,3 151,7 0,292 ETV5 molecule)

histone cluster 5129 0,0253564 0,2702985 8,2 28,1 0,292 HIST1H2BG 1, H2bg AXIN1 up- 691 0,0008908 0,070427 101,5 348,8 0,291 AXUD1 regulated 1 phosphodieste rase 4D interacting protein (myomegalin) /// phosphodieste rase 4D interacting protein 3761 0,014438 0,2098904 6,5 22,3 0,291 PDE4DIP (myomegalin) hypothetical protein 377 0,0004005 0,0577756 87,2 300,9 0,29 LOC338758 LOC338758 protein phosphatase 1, regulatory (inhibitor) 3424 0,0124337 0,1985434 108,8 375,1 0,29 PPP1R15A subunit 15A

growth arrest and DNA- damage- 480 0,0005435 0,0615795 44,6 154,1 0,289 GADD45B inducible, beta 519 0,0006057 0,0635709 312,2 1079,5 0,289 SULF2 sulfatase 2 cysteine-rich protein 1 (intestinal) /// CRIP1 /// galactokinase 2095 0,0053196 0,138789 192 668,2 0,287 GALK2 2 998 0,0015714 0,0859576 276,9 968,9 0,286 NINJ1 ninjurin 1 hairy and enhancer of split 1, 3959 0,0159944 0,2208876 10,1 35,3 0,286 HES1 (Drosophila) hairy and enhancer of split 1, 6955 0,0433857 0,3410659 6 21 0,286 HES1 (Drosophila) growth arrest and DNA- damage- 420 0,0004472 0,0577884 81 284,5 0,285 GADD45B inducible, beta solute carrier family 12 (potassium/chl oride transporters), 2511 0,007372 0,1604794 14,3 50,4 0,284 SLC12A8 member 8 Guanylate binding protein 682 0,0008778 0,0701954 25,2 89,1 0,283 GBP5 5 Solute carrier family 16, member 3 (monocarboxyli c acid 3532 0,0130873 0,2025512 23,6 83,4 0,283 SLC16A3 transporter 4) Kruppel-like 3656 0,0137703 0,205933 201,6 711,3 0,283 KLF6 factor 6 kynureninase (L-kynurenine 4083 0,0169929 0,22755 4,8 17 0,282 KYNU hydrolase) 1098 0,001851 0,0921338 281,1 999,3 0,281 LMNA lamin A/C EH-domain 1583 0,0033092 0,114296 9,6 34,2 0,281 EHD1 containing 1 tumor- associated calcium signal 2712 0,0084385 0,1701235 9,9 35,2 0,281 TACSTD2 transducer 2 complement component (3b/4b) receptor 1 (Knops blood 3156 0,0109911 0,1904114 40,5 144,6 0,28 CR1 group) pre-B-cell colony enhancing 764 0,0010464 0,0748847 51,7 186,5 0,277 PBEF1 factor 1 chemokine-like 1721 0,0037698 0,1195727 14,1 51 0,276 CMKLR1 receptor 1

sema domain, immunoglobuli n domain (Ig), transmembran e domain (TM) and short cytoplasmic domain, (semaphorin) 2538 0,0075168 0,1619311 68,6 248,8 0,276 SEMA4A 4A epithelial membrane 4392 0,0194355 0,2419481 170 617,5 0,275 EMP1 protein 1 ATP-binding cassette, sub- family A (ABC1), 6907 0,042763 0,3384517 6,8 24,7 0,275 ABCA6 member 6 Transcribed 380 0,0004044 0,0577756 97,5 359,9 0,271 NA locus 611 0,0007363 0,0657513 203,8 752,9 0,271 LMNA lamin A/C

dual specificity 5036 0,0246041 0,2671226 24,2 89,3 0,271 DUSP4 phosphatase 4 ankyrin repeat 2156 0,00558 0,1413783 57,4 212,2 0,27 ANKRD37 domain 37

chromosome 3 open reading 139 0,0001119 0,0439272 30 111,6 0,269 C3orf59 frame 59

chromosome 5 open reading 348 0,0003527 0,0554134 6,3 23,4 0,269 C5orf20 frame 20 ATP-binding cassette, sub- family A (ABC1), 4827 0,0228369 0,2586565 13,4 49,8 0,269 ABCA1 member 1 ST8 alpha-N- acetyl- neuraminide alpha-2,8- sialyltransferas 2634 0,008077 0,167497 21,7 81,5 0,266 ST8SIA4 e 4 RAS protein activator like 1 3174 0,0111366 0,1918206 52,5 197,3 0,266 RASAL1 (GAP1 like) Metastasis 3418 0,0124066 0,1984223 8,6 32,3 0,266 MTSS1 suppressor 1 sialic acid binding Ig-like lectin 1, sialoadhesin /// sialic acid binding Ig-like lectin 1, 2130 0,0054637 0,1402478 11,7 44,3 0,264 SIGLEC1 sialoadhesin GDNF family receptor alpha 3908 0,015635 0,2187028 14,3 54,1 0,264 GFRA2 2 chromosome 11 open reading frame 7158 0,0453807 0,3466317 61,2 232,8 0,263 C11orf32 32 pellino homolog 1 168 0,0001458 0,0471813 46,8 178,5 0,262 PELI1 (Drosophila) suppressor of variegation 4- 20 homolog 1 1624 0,0034556 0,1161645 67,8 259,1 0,262 SUV420H1 (Drosophila) Transcribed 724 0,0009423 0,0711606 37 141,5 0,261 NA locus Notch homolog 4462 0,0199305 0,2441497 19,6 75 0,261 NOTCH2 2 (Drosophila) 41 2,47E-05 0,0312927 77,4 297,4 0,26 NA NA chemokine (C- X-C motif) 1682 0,0036319 0,1177064 219,5 845,4 0,26 CXCR4 receptor 4 CDNA FLJ44441 fis, clone UTERU202024 3312 0,0118854 0,196206 36,8 141,9 0,259 NA 2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1530 0,0031351 0,1120337 209,6 811,6 0,258 NFKBIZ inhibitor, zeta v-ets erythroblastosi s virus E26 oncogene homolog 2 1997 0,0048667 0,1332433 63,3 245,6 0,258 ETS2 (avian) peptidylprolyl isomerase F 1646 0,0035013 0,1161645 177,4 690,7 0,257 PPIF (cyclophilin F) epithelial membrane 4553 0,0206233 0,2476563 8,7 33,9 0,257 EMP1 protein 1 activating transcription 697 0,0009019 0,070427 113,7 447,5 0,254 ATF5 factor 5 1930 0,0045727 0,1294851 38,7 152,5 0,254 NA NA

3869 0,0153912 0,2174619 102,9 404,8 0,254 CD93 CD93 molecule DnaJ (Hsp40) homolog, subfamily B, 4215 0,0179857 0,2333021 91,8 364,3 0,252 DNAJB1 member 1 ATP-binding cassette, sub- family A (ABC1), 5324 0,0271158 0,2784666 20,6 81,8 0,252 ABCA1 member 1 myristoylated alanine-rich protein kinase 3713 0,0141432 0,2082169 17,3 69,6 0,249 MARCKS C substrate Epstein-Barr virus induced gene 2 (lymphocyte- specific G protein- coupled 104 7,34E-05 0,0382725 555,4 2243,4 0,248 EBI2 receptor) Ribosomal protein L29 /// Ribosomal 1169 0,0020522 0,0959829 6,1 24,6 0,248 RPL29 protein L29 peptidylprolyl isomerase F 1297 0,0024278 0,1023071 325 1314,3 0,247 PPIF (cyclophilin F)

arachidonate 5- 161 0,0001347 0,0457436 18,8 76,5 0,246 ALOX5 lipoxygenase MAX dimerization 719 0,0009332 0,0708877 20,8 84,5 0,246 MXD1 protein 1 Sulfotransferas e family, cytosolic, 1A, phenol- preferring, 1259 0,0022751 0,0987873 49,4 201,9 0,245 SULT1A4 member 4 heat shock 70kDa protein 1A /// heat HSPA1A /// shock 70kDa 7429 0,0484048 0,3562249 719,2 2939,7 0,245 HSPA1B protein 1B THAP domain containing, apoptosis associated 5533 0,0290296 0,2867964 14,9 61,1 0,244 THAP2 protein 2

amphiregulin (schwannoma- derived growth factor) /// similar to Amphiregulin precursor (AR) (Colorectum cell-derived AREG /// growth factor) 4487 0,0201566 0,2456122 9,3 38,3 0,243 LOC727738 (CRDGF) interleukin 1, 6857 0,0422346 0,3367178 8,4 34,5 0,243 IL1A alpha phorbol-12- myristate-13- acetate- induced 2730 0,0085533 0,1712917 115,1 475 0,242 PMAIP1 protein 1

leukocyte immunoglobuli n-like receptor, subfamily A (without TM domain), 4011 0,0164667 0,2244523 29,3 121 0,242 LILRA3 member 3

Fc fragment of IgG, low affinity IIc, receptor for 2350 0,0064991 0,1512078 185,8 776,3 0,239 FCGR2C (CD32) baculoviral IAP repeat- 143 0,0001165 0,0439272 76,3 320,2 0,238 BIRC3 containing 3 growth arrest and DNA- damage- 133 0,0001061 0,0431325 107,2 454,7 0,236 GADD45B inducible, beta enolase 2 (gamma, 869 0,001263 0,0791194 16,5 70 0,236 ENO2 neuronal) TBC1 domain family, member 935 0,001413 0,082425 25,1 106,6 0,235 TBC1D22A 22A ankyrin repeat 217 0,0001922 0,0483249 87,1 376,5 0,231 ANKRD28 domain 28 colony stimulating factor 2 receptor, alpha, low- affinity (granulocyte- 158 0,0001325 0,0457 13 56,5 0,23 CSF2RA macrophage) Myristoylated alanine-rich protein kinase 735 0,00097 0,0720258 47,8 207,4 0,23 MARCKS C substrate epithelial stromal interaction 1 1561 0,0032564 0,1138946 31,1 136 0,229 EPSTI1 (breast) interleukin 6 (interferon, 3067 0,0104647 0,1863882 16,2 70,7 0,229 IL6 beta 2) OTU domain 269 0,0002605 0,0525339 147,9 647,7 0,228 OTUD1 containing 1 family with sequence similarity 49, 635 0,0007761 0,066824 14,3 63 0,227 FAM49A member A zinc finger 52 3,11E-05 0,0326999 102,7 456,8 0,225 ZNF395 protein 395 immediate early response 1227 0,0022013 0,0980283 196,5 874 0,225 IER3 3 Hypothetical protein 1502 0,0030524 0,1109355 91,8 407,5 0,225 FLJ43663 FLJ43663

eukaryotic translation initiation factor 3466 0,0126931 0,2001833 18,4 81,8 0,225 EIF4G3 4 gamma, 3 chondroitin sulfate proteoglycan 2 4255 0,0182507 0,2344871 4,7 20,9 0,225 CSPG2 (versican) zinc finger protein 395 /// ZNF395 /// F-box protein 6 6,10E-06 0,0302321 43,9 197,1 0,223 FBXO16 16 Fc fragment of IgA, receptor 5652 0,0300413 0,2906065 8,4 37,6 0,223 FCAR for solute carrier family 2 (facilitated glucose transporter), 9 7,10E-06 0,0302321 245,8 1104,8 0,222 SLC2A3 member 3 hypothetical RP1- protein 503 0,0005775 0,062773 35 158 0,222 93H18.5 LOC441168

tumor necrosis factor, alpha- induced 1640 0,0034874 0,1161645 384,7 1735,6 0,222 TNFAIP3 protein 3

nuclear factor of kappa light polypeptide gene enhancer in B-cells 576 0,0006839 0,0649171 277,2 1261,7 0,22 NFKBIZ inhibitor, zeta

tumor necrosis factor, alpha- induced 2362 0,0065943 0,1525742 178 808,1 0,22 TNFAIP3 protein 3

nuclear factor of kappa light polypeptide gene enhancer in B-cells 233 0,0002077 0,0487168 1274,3 5818,1 0,219 NFKBIA inhibitor, alpha activating transcription 527 0,0006168 0,0635709 49,1 223,9 0,219 ATF5 factor 5 Hypothetical protein 1001 0,001574 0,0859576 54,8 250,1 0,219 FLJ43663 FLJ43663 hypothetical protein 5473 0,0284547 0,2842101 162,6 741,7 0,219 MGC14376 MGC14376 pre-B-cell colony enhancing 207 0,000187 0,0483249 196,2 900 0,218 PBEF1 factor 1

interleukin 3 receptor, alpha 1458 0,0029055 0,1089563 27,4 125,7 0,218 IL3RA (low affinity) metastasis 1011 0,0016028 0,0866252 112,6 518,5 0,217 MTSS1 suppressor 1 colony stimulating factor 2 receptor, alpha, low- affinity (granulocyte- 190 0,0001673 0,0481428 36,7 170,3 0,216 CSF2RA macrophage) superoxide dismutase 2, 3108 0,0106649 0,1876137 212,2 984,4 0,216 SOD2 mitochondrial interleukin 7 receptor /// interleukin 7 1544 0,0032008 0,1132377 136,9 639,2 0,214 IL7R receptor solute carrier family 7, (cationic amino acid transporter, y+ system) 3210 0,0113416 0,1931782 26,4 124,7 0,212 SLC7A11 member 11 tensin 1 /// 144 0,0001166 0,0439272 62 293,6 0,211 TNS1 tensin 1 86 5,98E-05 0,0367348 20,3 96,5 0,21 MYO1G myosin IG

Fc fragment of IgG, low affinity IIb, receptor 5635 0,0298472 0,2895961 562,7 2688,6 0,209 FCGR2B (CD32) interleukin 7 1516 0,0030885 0,1113787 68,6 329,5 0,208 IL7R receptor ST8 alpha-N- acetyl- neuraminide alpha-2,8- sialyltransferas 1647 0,0035033 0,1161645 17,4 83,8 0,208 ST8SIA4 e 4 chemokine (C- C motif) receptor 7 /// chemokine (C- C motif) 4450 0,0198434 0,2438063 28,2 135,9 0,208 CCR7 receptor 7 runt-related transcription 586 0,0007082 0,0657513 107,1 517,2 0,207 RUNX3 factor 3 runt-related transcription 1243 0,0022422 0,0985952 24,9 120 0,207 RUNX3 factor 3

Fc fragment of IgG, low affinity IIc, receptor for 3341 0,0120555 0,1972866 363,6 1758,4 0,207 FCGR2C (CD32) solute carrier family 2 (facilitated glucose transporter), 1 2,20E-06 0,0302321 171,6 835,3 0,205 SLC2A3 member 3 317 0,0003138 0,0541231 49,6 241,4 0,205 MYO1G myosin IG myristoylated alanine-rich protein kinase 1408 0,0027359 0,1062396 84,3 412,9 0,204 MARCKS C substrate

pleckstrin homology-like domain, family 3797 0,01477 0,2126667 38,5 191,8 0,201 PHLDA2 A, member 2 chemokine (C- C motif) ligand 1440 0,0028327 0,1075541 154 768,3 0,2 CCL17 17 solute carrier family 7, (cationic amino acid transporter, y+ system) 6066 0,0340341 0,3067086 234,9 1190,7 0,197 SLC7A11 member 11 Transcribed 1054 0,0017104 0,088725 453,1 2322,8 0,195 NA locus zinc finger protein 395 /// ZNF395 /// F-box protein 13 9,30E-06 0,0302321 49 252,2 0,194 FBXO16 16 hypothetical RP1- protein 550 0,0006456 0,0639658 57,9 299,9 0,193 93H18.5 LOC441168 v-ets erythroblastosi s virus E26 oncogene homolog 2 474 0,0005291 0,0609252 62,9 328,6 0,191 ETS2 (avian) chemokine (C- C motif) ligand 7069 0,044523 0,3443357 26,7 139,9 0,191 CCL23 23 zinc finger 4 3,40E-06 0,0302321 55,2 291 0,19 ZNF395 protein 395 hypothetical protein 632 0,0007726 0,0666535 33,6 177,2 0,19 FLJ43663 FLJ43663 family with sequence similarity 49, member A /// family with sequence similarity 49, 58 3,86E-05 0,0353731 28,3 150 0,189 FAM49A member A heat shock 70kDa protein 2477 0,0071959 0,1587803 121,4 644,5 0,188 HSPA1B 1B colony stimulating factor 2 receptor, alpha, low- affinity (granulocyte- 450 0,0004904 0,0595242 37,9 202,3 0,187 CSF2RA macrophage) solute carrier family 2 (facilitated glucose transporter), 18 1,35E-05 0,0302321 128,7 693,8 0,186 SLC2A3 member 3 interleukin-1 receptor- associated 6180 0,0352412 0,3117492 20,3 110,3 0,184 IRAK2 kinase 2 Phosphodieste rase 4D interacting protein 4217 0,0180001 0,2333254 13,3 72,8 0,183 PDE4DIP (myomegalin)

Fc fragment of IgG, low affinity IIIa, receptor (CD16a) /// Fc fragment of IgG, low affinity FCGR3A /// IIIb, receptor 4428 0,0196773 0,2429649 53,2 292,1 0,182 FCGR3B (CD16b) solute carrier family 7, (cationic amino acid transporter, y+ system) 6203 0,0354565 0,3125236 214,3 1180,4 0,182 SLC7A11 member 11 angiogenin, ribonuclease, RNase A family, 5 /// ribonuclease, ANG /// RNase A 1637 0,0034811 0,1161645 12,8 70,6 0,181 RNASE4 family, 4 interleukin 1, 6300 0,0365111 0,3168642 42,3 235,3 0,18 IL1B beta

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), 463 0,0005086 0,0600598 55,6 310 0,179 SERPINA1 member 1 chromosome 15 open reading frame 2070 0,0052033 0,137435 111,3 621,8 0,179 C15orf48 48 adrenomedulli 3882 0,0154681 0,2178228 214,5 1195,5 0,179 ADM n solute carrier family 2 (facilitated glucose transporter), 2 3,00E-06 0,0302321 223,9 1297,6 0,173 SLC2A3 member 3 epithelial membrane 3507 0,0129741 0,2021636 8,8 52,2 0,169 EMP1 protein 1 ethanolamine kinase 1 /// ethanolamine 1821 0,004146 0,1242557 24,6 147,1 0,167 ETNK1 kinase 1

954 0,0014531 0,0832791 38,6 232,3 0,166 ITGB7 integrin, beta 7 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 3185 0,0111947 0,1921 40,8 246,3 0,166 SERPINE1 1), member 1 PR domain containing 1, with ZNF 1081 0,0017928 0,090618 40,6 246,9 0,164 PRDM1 domain solute carrier family 2 (facilitated glucose transporter), 3 3,30E-06 0,0302321 387,6 2412,1 0,161 SLC2A3 member 3 GDNF family receptor alpha 2642 0,0080987 0,167497 18,7 116 0,161 GFRA2 2 nucleotide- binding oligomerization domain 1210 0,0021576 0,0974932 20,2 127,4 0,159 NOD2 containing 2 nuclear receptor subfamily 4, group A, 2696 0,0083672 0,1695229 15 94,6 0,159 NR4A2 member 2 ATP-binding cassette, sub- family G (WHITE), 4414 0,0195717 0,2424292 15,9 101 0,157 ABCG1 member 1 colony stimulating factor 2 receptor, alpha, low- affinity (granulocyte- 211 0,0001905 0,0483249 55 353,2 0,156 CSF2RA macrophage) superoxide dismutase 2, 862 0,0012509 0,0791194 8,7 55,8 0,156 SOD2 mitochondrial

dual specificity 2376 0,0066433 0,1528714 133 850,2 0,156 DUSP6 phosphatase 6

FBJ murine osteosarcoma viral oncogene 1577 0,0032969 0,1142231 23,4 150,6 0,155 FOSB homolog B ribonuclease, RNase A 228 0,0002048 0,0487168 7,9 51,6 0,153 RNASE4 family, 4 Fc fragment of IgG, low affinity IIa, receptor 543 0,0006333 0,0635709 89,4 591,5 0,151 FCGR2A (CD32)

dual specificity 858 0,0012476 0,0791194 84 558,1 0,151 DUSP6 phosphatase 6

ADAM metallopeptida se domain 19 216 0,000192 0,0483249 13,7 91,4 0,15 ADAM19 (meltrin beta) Transcribed 272 0,000266 0,0525339 23,1 154,3 0,15 NA locus hypothetical 1096 0,0018381 0,0916217 10 68 0,147 LOC401317 LOC401317

collectin sub- family member 12 /// collectin sub-family 15 1,34E-05 0,0302321 57,9 400,1 0,145 COLEC12 member 12

TSC22 domain family, member 598 0,0007244 0,0657513 70,6 493,7 0,143 TSC22D3 3 interleukin 1, 4401 0,0195034 0,2422309 16,5 115,5 0,143 IL1B beta matrix metallopeptida se 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV 201 0,0001817 0,0483249 54 379,3 0,142 MMP9 collagenase) nuclear receptor subfamily 4, group A, 2088 0,005283 0,1383372 16,2 115,6 0,14 NR4A2 member 2

Leucine rich repeat (in FLII) interacting 1285 0,0023832 0,1013463 47,8 345,4 0,138 LRRFIP2 protein 2 CDNA FLJ32379 fis, clone SKMUS10000 5877 0,0320154 0,2978462 12,1 88,1 0,137 NA 30 interleukin 4 1031 0,0016632 0,0879972 37,8 278 0,136 IL4I1 induced 1

tumor necrosis factor, alpha- induced 3727 0,0142158 0,2085454 5,9 45 0,131 TNFAIP6 protein 6 3928 0,0157858 0,2197061 26,4 202,1 0,131 LGMN legumain arachidonate 5- 159 0,0001329 0,0457 19,5 150 0,13 ALOX5 lipoxygenase

dual specificity 987 0,0015486 0,0856868 148,3 1160,4 0,128 DUSP6 phosphatase 6 Solute carrier family 2 (facilitated glucose transporter), 389 0,000413 0,0577756 13,1 106 0,124 SLC2A3 member 3

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), 539 0,0006305 0,0635709 20,4 169,2 0,121 SERPINA1 member 1 hemoglobin, delta /// hemoglobin, 1891 0,0044588 0,128789 13,2 108,7 0,121 HBD delta Active BCR- 394 0,0004171 0,0577756 37,5 314,6 0,119 ABR related gene

neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) /// neutrophil cytosolic factor 1B pseudogene /// neutrophil NCF1 /// cytosolic factor NCF1B /// 1C 582 0,0007025 0,0657513 29,2 245,1 0,119 NCF1C pseudogene ficolin (collagen/fibrin ogen domain 1459 0,0029117 0,1091139 40,1 337,1 0,119 FCN1 containing) 1 Fc fragment of IgA, receptor 4055 0,0168044 0,2265502 9,9 82,9 0,119 FCAR for regulator of G- protein 188 0,0001669 0,0481428 63,8 539,5 0,118 RGS1 signalling 1 ribonuclease, RNase A 307 0,0003062 0,0541231 9,7 82 0,118 RNASE4 family, 4 nuclear receptor subfamily 4, group A, 2364 0,0065969 0,1525742 18,7 160,1 0,117 NR4A2 member 2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 4668 0,0215721 0,2526681 28,6 248,9 0,115 SERPINE1 1), member 1 CDNA FLJ11041 fis, clone PLACE100440 7095 0,0447512 0,3448586 14,8 128,4 0,115 NA 5 ADAM metallopeptida se domain 8 /// ADAM metallopeptida 26 1,66E-05 0,0302321 37,8 332,8 0,114 ADAM8 se domain 8

GRB2-related 275 0,000268 0,0525339 15,2 133,8 0,114 GRAP adaptor protein chondroitin sulfate proteoglycan 2 223 0,0001971 0,0483249 7,2 66,8 0,108 CSPG2 (versican) heat shock 70kDa protein 6 (HSP70B@#$ 2979 0,0098859 0,1813981 29,2 274,5 0,106 HSPA6 %&) G protein- coupled receptor 109B /// G protein- coupled 3497 0,0129373 0,2021636 97,2 944,7 0,103 GPR109B receptor 109B regulator of G- protein 40 2,44E-05 0,0312927 7,5 73,7 0,102 RGS1 signalling 1

RasGEF domain family, 2040 0,0050832 0,1362133 18,3 182 0,101 RASGEF1B member 1B

arachidonate 5- 118 8,45E-05 0,0390536 137,7 1464,4 0,094 ALOX5 lipoxygenase adenylosuccin ate synthase 54 3,30E-05 0,0332026 10,2 110,1 0,093 ADSSL1 like 1 B-cell translocation gene 1, anti- 376 0,0003997 0,0577756 11,5 125,8 0,091 BTG1 proliferative chemokine (C- X-C motif) 1645 0,0035005 0,1161645 68,7 837,8 0,082 CXCL2 ligand 2 GTP cyclohydrolase 1 (dopa- responsive 1698 0,0036706 0,118192 12,8 161,8 0,079 GCH1 dystonia) 3868 0,0153885 0,2174619 296,9 3936 0,075 IL8 interleukin 8

tumor necrosis factor, alpha- induced 1755 0,0038883 0,1210936 7,5 101,8 0,074 TNFAIP6 protein 6

chemokine (C- C motif) ligand 18 (pulmonary and activation- 2941 0,0096646 0,1796709 135,6 1894,5 0,072 CCL18 regulated) egl nine homolog 3 (C. 478 0,000537 0,0614236 7,8 113 0,069 EGLN3 elegans)

chemokine (C- C motif) ligand 18 (pulmonary and activation- 2915 0,0094757 0,1777303 110,1 1628,2 0,068 CCL18 regulated) egl nine homolog 3 (C. 55 3,34E-05 0,0332026 8,5 129 0,066 EGLN3 elegans) chondroitin sulfate proteoglycan 2 (versican) /// chondroitin sulfate proteoglycan 2 59 3,91E-05 0,0353731 5,5 90 0,061 CSPG2 (versican) heat shock 70kDa protein 6 (HSP70B@#$ 2501 0,0073123 0,1597509 40 664,7 0,06 HSPA6 %&) chemokine (C- X-C motif) 2186 0,0057028 0,1426225 13,9 251,5 0,055 CXCL3 ligand 3 3292 0,0117472 0,1951027 52,7 1164,6 0,045 IL8 interleukin 8 chondroitin sulfate proteoglycan 2 105 7,37E-05 0,0382725 14,8 362,1 0,041 CSPG2 (versican) 236 0,0002178 0,050448 9,7 258,6 0,038 EREG epiregulin

triggering receptor expressed on 292 0,0002864 0,0532207 22,8 601,7 0,038 TREM1 myeloid cells 1 interleukin 1 receptor, type 2643 0,0080998 0,167497 30 813,8 0,037 IL1R2 II interleukin 1 receptor, type 3624 0,0135893 0,2049724 56,1 1572,4 0,036 IL1R2 II chondroitin sulfate proteoglycan 2 108 7,59E-05 0,0382725 10,1 289,4 0,035 CSPG2 (versican) ribonuclease, RNase A family, 1 310 0,0003075 0,0541231 35,2 2805,2 0,013 RNASE1 (pancreatic)