Zhenyu Xiong (716) 907-1763 · Zhenyuxi@Buffalo.Edu 875 Ellicott St, 8Th Floor, Buffalo, NY, 14203

Zhenyu Xiong (716) 907-1763 · [email protected] 875 Ellicott St, 8th Floor, Buffalo, NY, 14203

Education

Ph.D. in Medical Physics (Expected graduation: May 2018) August 2014 - Present M.Sc. in Medical Physics August 2014 - September 2016 University at Buffalo, the State University of New York, Buffalo, NY (GPA: 3.9)

B.Sc. in Applied Physics August 2010 - June 2014 Hefei University of Technology (HFUT), Hefei, China (GPA: 3.6)

Board Certification Passed the American Board of Radiology (ABR) Medical Physics Part I Exam August 2017

Research Experience

Graduate Research Assistant, University at Buffalo (SUNY), Buffalo, NY August 2014 - Present Toshiba Stroke and Vascular Research Center, Buffalo, NY Advisor: Dr. Daniel Bednarek & Dr. Stephen Rudin • (August 2014- Present) Aid in designing a real time Skin Dose Tracking System software (DTS) for fluoroscopic interventions which is licensed to Toshiba Medical System Corporation. • (August 2016 – Present) Principal developer to a system to show the scattered radiation dose rate distribution for radiologists and staffs in the room next to an interventional C-arm fluoroscopy system. • (May 2015 - October 2017) Developed a method for real-time eye lens dose estimation and implemented it into DTS. • (March 2016 - August 2017) Developed a method for calculating the entrance skin dose distribution by using a backscatter point spread function for fluoroscopically-guided interventions. • (August 2014 - June 2016) Developed a system for automatically calculating organ and effective dose for fluoroscopically-guided procedures and CBCT scans. • (June 2015 – May 2016) Developed a lateral head shielding for eye lens dose reduction during neuro-CBCT and interventional fluoroscopic procedures. • (August 2014 – July 2015) Contributed to upgrading DTS dose calculation capability while using Compensation filters, ROI beam attenuators and patient support systems. • Other laboratory work including: ˖ Review research project proposals and project timelines. ˖ Help colleagues in dose measurements with ion-chamber and radiochromic film. ˖ Help colleagues in Monte Carlo simulation.

Undergraduate Research Assistant, Hefei University of Technology August 2011 - May 2014 Cancer Hospital, Hefei Institutes of Physical Science, Chinese academy of science (CAS) Advisor: Dr. Hui Lin • (August 2012- May 2014) Contributed to the construction of an in-room kilovoltage (kV) x-ray imaging systems in the radiotherapy treatment room. • (March 2012 – April 2014) Contributed to the development of a Monte Carlo tool for dose verification of Accurate Radiation Therapy System (ARTS). • (August 2011 – May 2013) SRIM (The Stopping and Range of Ions in Matter) simulation of effects induced by low-energy Ar ion irradiation in silkworm eggs. • (August 2011 – August 2012) Received training for realization and operation medical linear accelerator and ancillary medical imaging equipment.

Clinical Experience

Assistant Radiation Safety Officer, Erie County Medical Center (ECMC), Buffalo, NY (August 2014-Present)

• Maintained >50 diagnostic x-ray imagers to ensure patient safety and effective delivery of radiation to achieve a diagnostic result and better image quality, abiding by NY state health regulations. • Annual quality assurance for primary diagnostic monitors in the hospital. • Assist the RSO to do the acceptance testing for shielding design of imaging facilities. • Led and trained a group of assistant radiation safety officers for quarterly and monthly clinical duties of film badge distribution and collection, nuclear medicine ALARA audits, swipe tests and sealed source leak test. • Monthly orientation lectures for all new hospital employees regarding radiation safety and imaging physics. • Distribution and collection of hundreds of radiation monitoring badges. • Periodic radioactive testing of the nuclear medicine department and radioactive waste storage areas.

Publications and Conference Experience

Peer Reviewed Journal Publications (8) · G. Xu, Z. Xiong, H. Wang, H. Jiang, B. Li, L. Liu, “Development of a 6DOF dynamic phantom for tumor target delineation and dose verification in radiotherapy planning.” Int. J. Radiat. Res. (2017) (Accepted) · Z. Xiong, S. Vijayan, S. Rudin, D. R. Bednarek. “Assessment of organ and effective dose when using region-of- interest (ROI) attenuators in CBCT and interventional fluoroscopy.” Journal of Medical Imaging (JMI) 4(3), 031210 (2017) · S. Vijayan, Z. Xiong, S. Rudin, D. R. Bednarek. “Calculation of the entrance skin dose distribution for fluoroscopically-guided interventions using a pencil beam backscatter model.” Journal of Medical Imaging (JMI) 4(3), 031203 (2017) · Y. Chen, F. Bo, W. Xia, S. Liu, P. Wang, W. Su, J. Xu, Z. Xiong, X. Yin, “Amygdala functional disconnection with the prefrontal-cingulate-temporal circuit in chronic tinnitus patients with depressive mood.” Prog. Neuropsychopharmacol. Biol. Psychiatry 79(Pt B):249-257 (2017) · H. Lin, C. Xie, Z. Xiong, D. Wu, Y. Zhang, R. Cao, FDS Team, “Effect of Different Geant4 Physical Models on Simulation of Radiotherapy Proton Beam.” Atomic Energy Science and Technology 49 (7) (2015) · Y. Dai, H. Lin, B. Wu, J. Cai, X. Pei, Z. Xiong, “Monte Carlo Simulation of Medical Linear Accelerator.” Journal of Hefei University of Technology (Natural Science) 38 (8):1143-1146 (2015) · Y. Chen, W. Xia, B. Luo, V. Muthaiah, Z. Xiong, J. Zhang, J. Wang, R. Salvi, G. Teng, “Frequency- specific alternations in the amplitude of low-frequency fluctuations in chronic tinnitus.” Front. Neural Circuits 9:67 (2015) · Z. Xiong, H. Lin, J. Cai, Y. Dai, Y. Zhang, C. Zhu, “Monte Carlo Simulation on the Irradiation Damage of Contaminative Electrons to the Skin Cell in External Radiotherapy.” Nuclear Physics Review 31 (2) (2014) Peer Reviewed Conference Proceedings (11) · Z. Xiong, S. Vijayan, C. Guo, A. Shankar, S. Rudin, D. R. Bednarek, “Investigation of organ dose variation with adult head size and pediatric age for neuro-interventional projections.” SPIE Medical Imaging 2018 (Accepted). · C. Guo, Z. Xiong, S. Vijayan, S. Rudin, D. R. Bednarek, “Developing a database of 3D scattered radiation distributions for a c-arm fluoroscope as a function of exposure parameters and phantom.” SPIE Medical Imaging 2018 (Accepted). · S. Vijayan, Z. Xiong, C. Guo, S. Rudin, D. R. Bednarek, “Calculation of the forward-scatter dose distribution from the patient table for fluoroscopically-guided interventions using a convolution technique.” SPIE Medical Imaging 2018 (Accepted). · J. Kilian-Meneghin, Z. Xiong, C. Guo, S. Rudin, D. R. Bednarek, “Evaluation of methods of displaying the real-time scattered radiation distribution during fluoroscopically-guided interventions for staff dose reduction.” SPIE Medical Imaging 2018 (Accepted). · S. V. Setlur Nagesh, J. Hinaman, K. Sommer, Z. Xiong, C.N. Ionita, D. R. Bednarek, S. Rudin, “A simulation platform using 3D printed neurovascular phantoms for clinical utility evaluation of new imaging technologies.” SPIE Medical Imaging 2018 (Accepted). · Z. Xiong, S. Vijayan, S. Rudin, D. R. Bednarek, “Organ and effective dose reduction for region-of- interest (ROI) CBCT and fluoroscopy.” Proc. SPIE 10132, Medical Imaging 2017: Physics of Medical Imaging, 1013242 (2017). · Z. Xiong, S. Vijayan, S. Rudin, D. R. Bednarek, “Monte Carlo investigation of backscatter point spread function for x-ray imaging examinations.” Proc. SPIE 10132, Medical Imaging 2017: Physics of Medical Imaging, 1013243 (2017). · J. Kilian-Meneghin, Z. Xiong, S. Rudin, A. Oines, D. R. Bednarek, “Evaluation of methods to produce an image library for automatic patient model localization for dose mapping during fluoroscopically guided procedures.” Proc. SPIE 10132, Medical Imaging 2017: Physics of Medical Imaging, 1013245 (2017). · S. Vijayan, Z. Xiong, A. Shankar, S. Rudin, D. R. Bednarek, “Skin dose mapping for non-uniform x- ray fields using a backscatter point spread function.” Proc. SPIE 10132, Medical Imaging 2017: Physics of Medical Imaging, 101320U (2017). · Z. Xiong, S. Vijayan, V. Rana, A. Jain, S. Rudin, D. R. Bednarek, “Lens of the eye dose calculation for neuro-interventional procedures and CBCT scans of the head.” Proc. SPIE 9783, 97832V-15 (2016). · S. Vijayan, Z. Xiong, S. Rudin, D. R. Bednarek, “A system to track skin dose for neuro-interventional cone-beam computed tomography (CBCT).” Proc. SPIE 9783, 97832X-7 (2016).

Peer Reviewed Abstracts (15) · Z. Xiong, S. Vijayan, C. Guo, S. Rudin, D. R. Bednarek, “Dose Reduction to the Lens of the Patient's Eye when Using Small Lead Shields over the Temporal Region of the Head and its Effect on Image Quality for Neuro Cone-Beam Computed Tomography (CBCT) Scans and Interventional Fluoroscopic Procedure.” RSNA 2017 (SSC14-08) (2017). (Oral Presentation at 2017 RSNA) · Z. Xiong, J. Kilian-Meneghin, S. Vijayan, C. Guo, S. Rudin, D. R. Bednarek “A Method for Eye Lens Dose Estimation during Fluoroscopically-Guided Neuro-Interventional Procedures.” Med. Phys. 44(6) (2017). (Oral Presentation at 2017 AAPM) · Z. Xiong, S. Vijayan, C. Guo, P. Choudhary, S. Rudin, D. R. Bednarek, “Lateral Head Shielding for Eye Lens Dose Reduction for Neuro-CBCT and Interventional Fluoroscopic Procedures.” Med. Phys. 44(6) (2017). (Oral Presentation at 2017 AAPM) · C. Guo, Z. Xiong, S. Vijayan, S. Rudin, D. R. Bednarek “Scattered Radiation Dose-Rate Distribution around an Interventional C-Arm Fluoroscope and Variation with Exposure Parameters.” Med. Phys. 44(6) (2017). (Oral Presentation at 2017 AAPM)

· P. Choudhary, S. Vijayan, B. Karthikeyan, Z. Xiong, S. Rudin, D. R. Bednarek “Real-Time, Image- Frame-Specific Magnification Factor Determination during Fluoroscopically-Guided Interventions.” Med. Phys. 44(6) (2017). (Oral Presentation at 2017 AAPM) · Z. Xiong, S. Vijayan, A. Oines, S. Rudin, D. R. Bednarek, “Automatic Calculation of Organ and Effective Dose for CBCT and Interventional Fluoroscopic Procedures.” Med. Phys. 43(6), 3749 (2016). (Oral Presentation at 2016 AAPM) · Z. Xiong, S. Vijayan, J. Kilian-Meneghin, S. Rudin, D. R. Bednarek, “A Comparison of Head Phantoms Used for Dose Determination in Imaging Procedures.” Med. Phys. 43(6), 3640 (2016). (Oral Presentation at 2016 AAPM) · S. Vijayan, Z. Xiong, A. Shankar, S. Rudin, D. R. Bednarek, “A Backscatter Point Spread Function for Entrance Skin Dose Determination.” Med. Phys. 43(6), 3748-3749 (2016). (Oral Presentation at 2016 AAPM) · S. Vijayan, Z. Xiong, S. Rudin, D. R. Bednarek, “Kerma Area Product Calculation for Non-Uniform X-Ray Fields Using a Skin Dose Tracking System.” Med. Phys. 43(6), 3716 (2016). (Poster Presentation at 2016 AAPM) · Z. Xiong, S. Vijayan, V. Rana, S. Rudin, D. R. Bednarek, “A System for Automatically Calculating Organ and Effective Dose for Fluoroscopically-Guided Procedures.” Med. Phys. 42(6):3583 (2015). (Poster Presentation at 2015 AAPM) · N. Islam, Z. Xiong, S. Vijayan, S. Rudin, D. R. Bednarek, “The Contribution to Skin Dose Due to Scatter from the Patient Table and the Head Holder during Fluoroscopy.” Med. Phys. 42 (6):3254 (2015). (Poster Presentation at 2015 AAPM) · S. Vijayan, V. Rana, Z. Xiong, S. V. Setlur Nagesh, S. Rudin, D. R. Bednarek, “A Real‐Time Skin‐ Dose Mapping System for Region‐Of‐Interest (ROI) Fluoroscopy.” Med. Phys. 42 (6):3717 (2015). (Oral Presentation at 2015 AAPM) · S. Vijayan, V. Rana, S. V. Setlur Nagesh, Z. Xiong, S. Rudin, D. R. Bednarek, “Comparison of Kerma- Area-Product between the Micro-Angiographic Fluoroscope (MAF) and a Flat Panel Detector (FPD) as Used in Neuro-Endovascular Procedures.” Med. Phys. 42 (6):3253 (2015). (Poster Presentation at 2015 AAPM) · Z. Xiong, H. Lin, J. Jing, J. Cai, Y. Dai, “Research of the Irradiation Damage to the Skin Cell by the Contaminative Electron in External Radiotherapy.” Med. Phys. 41(6):289 (2014). (Poster Presentation at 2014 AAPM) · J. Jing, H. Lin, Z. Xiong, “Effect of a Single Gold Nanoparticle with Different Sizes inside a Small Water Phantom.” Med. Phys. 41(6):255 (2014). (Poster Presentation at 2014 AAPM)

Other Presentations (4) · Z. Xiong, S. Vijayan, C. Guo, S. Rudin, D. R. Bednarek, “ Eye Lens Dose Reduction through Lateral Head Shielding and its Effect on Image Quality for Neuro CBCT and Interventional Fluoroscopic Procedures.” Upstate NYAAPM Fall Chapter Meeting (2017) · Z. Xiong, S. Vijayan, S. Rudin, D. R. Bednarek, “Effect of using region-of-interest (ROI) attenuators on organ and effective dose in CBCT scan and interventional fluoroscopy.” Upstate NYAAPM Spring Chapter Meeting (2017) · Z. Xiong, S. Vijayan, V. Rana, A. Jain, S. Rudin, D. R. Bednarek, “Monte Carlo Investigation of Eye Lens Dose in Interventional Neuroradiology Procedures and CBCT Scans of the Head.” Upstate NYAAPM Fall Chapter Meeting (2015) · Z. Xiong, S. Vijayan, V. Rana, S. Rudin, D. R. Bednarek, “Automatic Calculation of Organ and Effective Dose for Fluoroscopically-Guided Procedures.” Upstate NYAAPM Spring Chapter Meeting (2015)

Reviewer Experience Regular reviewer for: · BioMed Research International · Frontiers in Aging Neuroscience · Oncotarget · Imaging in Medicine · Interventional Cardiology · Neuropsychiatry · Advances in Applied Science Research

Technical Skills · Languages/tools: EGSnrc, Geant4, MCNPX, PCXMC, ImageJ, C++, CUDA, OpenGL, MATLAB. · Advanced knowledge and experience of working with various diagnostic imaging equipment.

Awards and Honors · Over 30 Publications in Peer Reviewed Journal Papers, Conference Proceedings, and Abstracts · JSMBS Dean's Scholarship August 2017 · Clara A. March Medical Scholarship August 2016 · Merit students of HFUT May 2014 · Outstanding project of innovative experiment project in HFUT July 2013 · First-class scholarship of HFUT June 2013

Professional Affiliations · Radiological Society of North America (RSNA) (2017- ) · American Association of Physicists in Medicine (AAPM) (2016- ) · International Society for Optics and Photonics (SPIE) (2016- ) · American College of Radiology (ACR) (2015- )

References Available upon request