The Newsletter of the NIH Alumni Association
Winter 2000 Vol. 12, No. 1 date
Varmus Presides Over NIH Budgets His Final ACD Meeting NIH Receives Major Budget Boost in Y2K By Car/(I Gamett President Clinton signed an omnibus WiLh the ink not yet dry on NIH"s budget bill on Nov. 29 that gives NIH fourth-straight large budget increase, its second record-breaking budget Dr. Harold Yarmus presided over his increase in a row. The FY 2000 13th and final meeting of the advisory appropriation for NIH is commillee to the NI H di rector (ACD) $17,9 13,470,000. an increase of more on Dec. 2, I 999. than $2.3 billion from FY 1999. and President CHnton had signed just a about $1.98 billion more than the week earlier the FY 2000 omnibus President's budget. which called for a spending bill that represented another 2 percent increase for the agency. The step closer to the goal of some I4.9 percent boost for FY 2000 advocates to double the agency's Dr. June E. Osborn matches the 14.9 increase reali zed in appropriation by 2004. The ACD FY 1999. which represented NIH 's meeting agenda was chock-full of Annual Meeting on June 17 biggest dollar increase ever. presentations and discussions about However, the bill includes $3 billion concrete ways-parti cularly construc Osborn Is NIHAA's 2000 in delayed ob ligations,.nol available tion projects both intramural and until Sept. 29. 2000, and an across-the extramural-to spend the latest and Public Service Awa1·dee any future largesse. (.~ee Budget. p. 13) As is customary, Yarmus spent the The NIH Alumni AssociaLion is opening minutes of the meeting giving pleased to announce that it will his advisors a summary of events since present the eighth NIHAA Public their last gathering. He welcomed Service Award to Dr. June E. Osborn In This Issue Page several new official ACD members at the next annual meeting, Saturday, Choppi11 delivers 1/tirrl Sha1111011 /,ec111re 3 including Phillip Williams. retired vice June 17, 2000, at the Mary Woodard chair of the Times Mirror Co.. who Lasker Center (the Cloister), on the Cale11dor ofexhibits mul e1·e11ts 5 had served previously as an ad hoc NI H can1pus. News from a11d about Nlf/AA members 6 ACD member; and Dr. Don Wilson, She is president of the Josiah Macy, vice president for medical affairs and Jr. Foundation in New York City and A h.!llerfro111 1he NII/AA preside111 10 dean of the University of Maryland has been an exemplary reviewer and 11 Worl A1111 ual Meeting ( co111i11ued fro111 p. 1) pediatrics and infectious disease. study section on HIV inactivation, and Osborn is also widely respected for the NIMH AIDS research advisory Update her basic research on cytomegalovi committee (1987-1988). ln 1993 and The NTHAA Update is the newsle11er of ru s. She was associate dean of the 1994. she was a member of the clinical the NIH Alumni Association. The NIHAA graduate school (for biological trials advisory commiuee, NJAID. and office is at 9101 Old Georgetown Rd. , sciences) at the University of Wiscon the AIDS Action Foundation. She also Bethesdll, MD 20814-1522: 301-530-0567: sin ( 1974- 1984) and then dean of the served as chair of the data safety [email protected]. school of public health at the Univer monitoring board for A IDS, prevention sity of Michigan ( 1984-1 993). She studies for NIAID ( 1995- 1997). Editor's Note assumed her present position in 1993 In addition, NlHAA members will The NIHAA Updaie welcomes le11ers (//Id and has received numerous honorary hear a talk by Dr. Allen M. Spiegel. news from its rellders. \Ve wish to provide awards, degrees and lectureships. newly appointed NlDDK director (see news about NIH to its alllmni and to She is a member of the National p. 23), entitled "Three decades of report alumni concems and i11fom1(11ion Academy of Sciences and the Ins1i1u1e research on signal transduction at NIH: llppoi111111e111s. honors. p11b/ic(llio11s and other i111eresti11g de1•elopme111s-to their of Medicine. a broad overview:' Spiegel is an colleagues. If you have news abo111 yourself In recem years Osborn has been both internationally recognized endocrinolo or other alumni or co111me11tsls11ggestio11s a major reviewer and advisor on gist whose research on signal transduc for the NIHAA Update. please drop a note public policy for AIDS and the sa fety tion has helped define the genetic basis to 1/te editor. We rese111e the right 10 edit of the blood supply. She has served of several endocrine diseases. materials. on 11 NTH review/advisory groups on As part of the program there will be Editor: ff(lrriet R. Greenwald AIDS. Her most widely known AfDS a short business meeting conducted by service was as chair, U.S. National NTHAA president Dr. William I. Gay. NIHM Newsletter Editorial Advisory Commission on AJDS (1989-1993). Newly elected members of the Committee ln 1995, she also chaired the WHO NIHAA's board of directors will be Jerome G. Green, Chaim1an Task Force on Global Blood Safety. announced. A reception with light Artrice Bader Her service at NfH has been particu refreshments will be part of the Michael M. Go11es111an larly prominent in dealing with A IDS. program. Invitations with details of Victoria A. Harden Early in the epidemic ( 1988), she the meeting will be mailed to local Carl Le11e111lwl served as chair of tbe special NIH members in May. Rober! G. Manin Abner Louis Notkins Saul Rosen SAVE THE DATE! Storm \Vhaley Richard G. Wva11 Saturday, June 17, 2000 NIHAA Newsleuer Board of Comrib111ing Editors The Year 2000 Annual Meeting Pamela £. Anderson of the NIH Alumni Association Linda Brown Giorgio Bernardi and the Public Service Award H. Franklin Bmm Henryk Eisenberg IOa.m. - I p.m. Donald S. Fredrickson um; A. Htmson at the Mary Woodard Lasker Center George Klein (the Cloister) Bldg. 60, NIH Richard M. Krause Bethesda, Md. Richard McMa1111s Carlos Monge Watch for invitation with details of the program. Roger Monier Ser111011r Perry Michael Sela · 2 WINTER 2 0 0 0 NIHAA Officers Wi/lit1111 I. Gay. Preside/If In Third James A. Shannon Lecture, Choppin Murray Goldstein, Vice President Jero111e G. Green, Vice President Asserts Role for Private Support of Biomedicine S1on11 Whaley, Secrete1ry/Treus11rer By Rich McMa1111s Past Presidents Willia111 S. Jordan. Jr.. 1997-1999 The billionaire down the block- the colorful tales of lhe instirute·s benefac Calvin 8. Baldwin, Jr., 1995-1997 Howard Hughes Medical Institute, tor, Howard Hughes Jr.. who set T'10111as J. Kennedy, Jr., 1993-1995 barely a mjle down Jones Bridge Rd. himself four goals in life: to be the .foe R. Held, 1991- 1993 from Nrn-senl an emissary Nov. 17 world's richest man, the world's most Gordon D. Wallace. 1990-1991 for the third annual James A. Shannon famous aviator, the best filmmaker and Board of Directors Lecture sponsored by the NIHAA. besc golfer. In pursuic of lhe lauer Alexander Adler Dr. Purnell Choppin. a virologist who goal, Choppin reported. be hired Artrice V. Bader had been president of HHM1 since he)jcoplers to film hjs golf swing. Carl G. Baker 1987 and who stepped down from that Cboppin began his lecture on a light W. E111111et1 Barkley note, first thanking NIH profusely for Edwin Becker post at the end of December, assured Robert L. Berger an audjence in Masur Auditorium that its support of his career (he left William R. Carroll HHMI's work "can onl y be comple multiple roles al Rockefeller Uni ver Peter Condli.ffe mentary (lo NJH's role) and incremen sity to take lhe leadership of HHMI, Cyrus R. Creveling tal. We are not a substitute:· abandoning a grant from NIAID that Jolin L Decker Murray Eden The $ 11 .8 billion medical research was in its 23rd year) then exhibiting a Ct1r/ Freus organization currentl y suppUes about tabloid headline from che Dec. 2 1. Samuel W. Greenliou.ve 22 percem of all nonprofit research 1993, issue of Weekly World News Samuel S. Herman support in biomedicine, funding some announcing that Howard Hughes had Jane Su11de/of Jones 331 investigators al 7 1 institutions. been brought back to life. He then Joseph Keyes, Jr. Lloyd W. Law said Choppin. ll has spent more than read a winy leuer from the IRS, which Ct1r/ Levell/ha/ $5 billion since 1985 on itS five areas had taken note of the headline and Lois F. Lipseu of speciaJty: cell biology and regula wanted Choppin to be aware of the lax Walter Magruder ti on, genetics, immunology, neuro consequences of such a resurrecti on. Kathleen McCor111ick science and structural biology; a new "The IRS docs have a sense of Carolyn Mcl-Jale Charles Miller. II field-computational biology-is just humor," he observed in an accent Gregory 0 'Conor emerging. Spending per year has risen giving away his roots in Louisiana. Paul D. Parkman from about $ 100 million in 1985-the While NLH is far and away the Joseph Perpicli year after HHMI sold its majn asset. world·s largest supporter of biomedical Karl Piez Hughes Aircraft, to General Motors for research, with a just-won FY 2000 Saul Schepam. Harley Sheffield about $4 billion- to mo1e llrnn $600 budget of almost $ 18 billion, the J,,awrence £. Slwlman million in 1999. government has not always been the Bernlwrd Witkop "This is small compared to the NIH principal funder of basic science. budget, but substantial in terms or Choppin noted that in 1930. half of the NlflAA Staff private support," he aid. WhiJe he financial support for medical research Harriet R. Greenll'a/d Mary Calley Hartman j uggled some lo ft y numbers-there came from the private sector. By were 170 billionaires in 1998. com 1940, tJ1c private sector contributed Tur. NJH ALUMNI ASSOCIATION THANKS pared to only 13 in 1982, and private only 27 percent of the total , u fi gure WYP.'1'11 -A YERST R1·~~f~\ll C ll OF AMElllCAN philanthropists, depending on which that dwindled to around 4 percent in H o~rn P1tonuc.-rs, M1mcK & Co., INc., economists you believe, are poised to 1980 and has remained in that vicinity R.O.W. S CIENCF.S, INC., AND TllE NIH contribuce anywhere from teens of ever since, he said. Ft:DEllAL CREDIT UNION FOil TllEIR tlELP IN UNDf:llWRITING TIIE PUllLISlllNG OF TilE trillions to many dozens of trillions to "The rapid descent (in pri vate N!Hr'\A UPDATE, AND f:XTF.NDS APPRECIA various good causes in the coming half support of cicnce) that began in the TION TO NIHAA Mt:~11rn1tS WllO CONTRlllUTI; century, he reported-Choppin DONA'rlONS UEYONl) TllEllt DUFS PAYMENT. leavened the dazzlement of sums with (See Cltoppin. p. 4) 3 N I H A A U P D A T E Clloppin ( comri1111ed from p. 3) forties con-esponds with the flowering of the NIH:· he said. "'The sense was that the government was doing such an effective job that foundations directed their resources elsewhere:· The Hughes fortune wac; built on an innovative drill bit that combined three drill heads on one stem, and proved ideal in smashing through rock 10 get at oil. Howard Hughes Sr.. who raced autos as a hobby. invented the 1001 and, rather than sell it to drillers. he Gathering before the Shannon Lecture, fou r NIHAA presidents meet with speaker Dr. leased it. assuring maximum profit Purnell Choppin (r). They are (from I) Dr. William I. Gay, Dr. Thomas J. Kennedy, Jr., ability. His son Howard Jr. took over Dr. William S. Jordan , Jr. , and Dr. Gordon Wallace. Hughes Tool Co. at age 18, and launched a Hollywood career while education in the history of the United HHMI also has spent $270 million pursuing an interest in aviation. Two States," he said. HHMI support of since 1984 on new laboratory years later. he was prescient enough 10 international cientists is particularly construction, and $85 million in dedicate his estate to medical research. rewarding when the Hughes cachet renovalions. "About 7 percent of Lhe Al age 25, he made an award around a given scientist prompts his HHMI budget is devoLed to equipment winning film about World War 11 or her government lo commit addi now." Choppin added. flying aces called Hel/ '.1· Angels. He Lional research money to the work. He recalled a frightening visit by later designed and built the H-1. a jet Choppin noted. staff from the U.S. Office of Technol that inll'oduced flush-rivet construc Choppin aid HHMI "will continue ogy Asse sment not long after he tion, and which broke both short 10 play an imponant role in private assumed presidency of HHMI. "They course and trans-Atlantic speed suppon of biomedicine. But pluralism asked me. ·What is it the federal records. H was only relatively late in of support is important in making this government can stop doing now that lil'c that the reclusive and men tally ill country the envy or the world in you 're here?' I assured Lh cm that we Hughes gained a darker public graduate educaiion and biomedical were no substitute." reputation among many Americans: research.'' Choppin said he is especially pleased Choppin asserLc; that 50 years from He said HHMrs flexibility allows it when his institute can work direcLly now. history will not recall him as a to move more rapidly than the will1 NI H. as in the Cloister program pitiful victim of ·'what was almost government can in newly emerging here on campus. or in a program that certainly obsessive-compulsive lields such as structural biology. In trains M ontgomery County science disorder," but as 1he hero who founded 1985- 1986. "within I I months we got teachers on campus, or when Hughes l-IHMT in l 953. an advisory commi1tee togeLher on money filled a gap in an NIH mouse Choppin touched on achievements structural biology, solicited applica genome sequencing project at Wash HHMI is most proud of. including a tions. identified leading laboratories. ington University. grants program that debuted in 1987 and funded beamli ne studies. It's very The lecture ended wilh a brief and which was budgeted in 1999 at difficult for any government to move question session, during which it $100 million.with programs reaching that rapidly." emerged that more th an 70 percent of elementary schools, high schools. He said Hughes has staying power in HHMT investigators also hold NIH colleges and postdoctoral studies. fields lhal are particularly intransient. grants. The fourth James A. Shannon "We have spent more than $430 and mentioned 9 years of work on the Lecture is scheduled for Wednesday. million in grant for undergraduate leptin gene by an H HM! scientist as Nov. 15. 2000. in Masur Auditorium, education. which is the largest private evidence of the institute's abi lity "to Bldg. 10, at 3:00 p.m. nonprofit initiative in support of suppon people rather ll1an projects." 4 WINTER 2 0 0 0 Calendar of Exhibits and Upcoming E1ents Exhibits Apr. 26-Margaret Pittman Lecture: FCRDC Spring Research Festival will Or. Janet Rowley. University of Chicago be held in Frederick. Md. Evenls of National Library of Medicine May 3--R. E. Dyer Lecture: interest to scientists and the general Extended through March 2001 in Dr. Barry E. Bloom. Harvard School of public are planned from 11 a.m. to 5 the NLM Rotunda, (Bldg. 38, 8600 Public Health -- ·'A View of Public Health p.m. each day. For information Rockville Pike). "Brea1h of Life." and Biomectical Research" contact Dr. Howard Young al an ex hi bit that examines the history May 17-NIH Director's Lecture: [email protected]. of asthma, the experiences of Dr. Cornelia Bargmann, UCSF. people with asthma and contempo "Mechanisms of odor discrimination in NIHAA Events rary efforts to understand the C. elegans ·· disease. For more information call June 7-General Motors Cancer The NJHAA Annual Meeting and 30 1-594-7170. Research Foundation Annual Public Service Award will be held Continuing until May 31, an Scientific Conference: Laureates lectures on Saturday, .June 17 at the Mary exhibit entitled "Classics of by winners of General Motors Prizes for Woodard Lasker Center (the Cloister). Traditional Chinese Medicine'' Cancer Research. Introduction by Bldg. 60. I 0 a.m.-1 p.m. from the History of Medicine Dr. Samuel A. Wells. Jr. The fourth J ames A. Shannon Division collect.ion. which is on Frederick Event Lecture Wednesday. Nov. 15. Speaker and title to be announced. view in the NLM lobby. For more On Wednesday, May 17 and Thursday. information call Young Rhee at May 18 the fourth annual Fort Detrick- 30 1-402-8917. DeWitt Stetten, .Jr., Museum The newest exhibit. "Researching Diseases: Dr. Roscoe Brady and Gaucher's Disease." opened on Jan. 31, 2000. The exhibit is on display in the hallway leading to Lipsett Amphitheater from the main ACRF lobby in Bldg. 10. For more information caJI the NfH Historical Office at 301-496-6610. NIH Events A1>ril-June 2000 The NIH Director's Wednesday Afternoon Lectures arc at 3 p.m. in Barbara Rodbell, widow of the late Nobelist Dr. Martin Rodbell , cuts the ribbon to open an Masur Auditorium. Bldg. 10. NIH exhibit featuring her husband's prize-winning research. Th e exhibit, located next to the Visitor Information Center In Bldg . 10, is a joint effort of Dr. Allen Spiegel (I), now NIDDK Following is a sample of speakers director; Dr. Victoria Harden (second from I), NIH historian; and Dr. Constantine Londos (r) and titles. For more information of NIDDK's Laboratory of Cellular and Developmental Biology, who was a colleague and and confi rmation of dates, times close friend of Rodbell 's. While working at NIH in the 1960's and 1970's, Rodbell identified and changes call Hilda Madine at the process of G protein signal transducllon, which won him and NIH grantee Dr. Allred 301-594-5595. Gilman the Nobel Prize In physiology or medicine in 1994. Rodbell died on Dec. 7, 1998, Apr. 12-Robert S. Gordon shortly after retiring as scientific director of NIEHS. Spiegel and Londos sponsored the Lecture: Dr. Steven Cummings. permanent exhibit as a way to explain to the visiting public the significance of Rodbell's UCSF, hosted by Epidemiology and long and productive career at NIH . A symposium , "G Proteins and Transmembrane Clinicnl Trials Interest Groups. Signaling: A Tribute to Martin Rodbell " in Masur Auditorium , which preceded the Nov. 5, 1999, ribbon-cutting , drew a standing-room-only crowd. 5 N I H A A UPDATE News from and about NIHAA Members and Foreign Chapters Capt. William H. Briner was a PHS introduced in Congress rhis year. Dr. Howard B. Dickier, who was at Commissioned Officer in tbe CC DeVita also received the 1999 Mary NlALD ( 1972-1999), lastly as chief pharmacy department who participated Watennan Award from the Breast of the Clinical Immunology Branch, in research involvi ng radioactive drugs Cancer Alliance of Greenwich. Conn. has been chosen associate dean for (1955-1970). and then worked ai Duke for ·'outstanding achievements in the research and graduate studies at University Hospital. He died Nov. 6. tight against cancer.'· Specifi call y, the University of Maryland School I 998. His widow, Betty Briner, sent us he was cited for his role in developing of Medicine. He will oversee the the fo llowing note: "[thought you combination chemotherapy programs schoor s $130 million research would be pleased to know that the that led to effective treatments for program that encompasses 23 award, formerly known as 'The Hodgkin's disease. diffuse large-cell medical specialties. American PhannaceuLical Association lymphoma and breast cancer. He has Academy of Pharmacy Practice and also been selected by the Leukemia Dr. Charles A. Dinarello, a former Management Distinguished Achieve Society of America to receive a 50th NIH clinical associate and senior ment Award in Nuclear Medicine,' has Anniversary Commemorative Award, investigator ( 1971-1977). is now been renamed in honor of Bill and wi ll recognizing his role in helping to professor of medicine at the University now be known as 'The William H. find the cure for leukemia and blood of Colorado School of Medicine in Briner Nuclear Pharmacy Practice related cancers. He has also been Denver. In April. he presented Lhe R. Distinguished Achievement Award:" elected to Lhe board of directors of E. Dyer Lecture. ''Anti-Cytokine the Association of American Cancer Therapies for lnnammat.ory Diseases." Dr. George Canellos, who was at NCl Institutes for a three-year term. Last year. he was also inducted into as a clinical associate ( 1963- 1965), a the National Academy of Sciences. senior investigator ( 1967-1974), and acting clinical director ( 1974- 1975). received the 1999 Key to the Cure Award from the Cure for Lymphoma Foundation. Canellos is the William Rosenberg professor of medicine at Harvard Medical School. He is also a senior staff member at Dana-Farber Cancer Institute. Brigham and Women's Hospital and Massachusens General Hospital and also editor-in chief of the Journal of Cli11ical Oncology. Dr. Vincent T. De Vita, Jr., former NCr di rector ( 1980-1988), is now head Dr. Sara Fuchs, who is at NEI as a visiting scientist, received the following note from Dr. of the Yale Cancer Center. He was Michael Sela: " On Oct. 26, the third C.B. Anfinsen Mem orial Lecture took place at the selected by U.S. Sen. Dianne Feinsrein Weizmann Institute of Science in Rehovot, Israel. The speaker was Chris Anlinsen's old CD-Cali f.) to co-chai r an advisory friend, Nobel laureate Prof. Edmond H. Fischer, (above) of the University of Washington, committee that will make recommen Seattle, and his topic was 'Reversible Protein Pho sp horylation-Today and Tomorrow.' He was introduced by Prof. Shmuel Shaltlel, who spent several years in Prof. Fischer's dations for revising and modernizing laboratory as a post-doctoral fellow. Fischer began with reminiscences of Chris Anlinsen Lhe National Cancer Act of 1971. and continued his lecture, which was of great interest and masterfully delivered, before a The committee. which comprises big and enthusiastic audience. Mrs. Libby Anlinsen, the widow of Chris, honored us with national leaders in the field, will seek her presence." Sela, chair of the event, added that the Weizmann Institute has taken opinions throughout the cancer responsibility fo r th e Anlinsen Lecture, which began at the initiative of NIH alumni in community about new legislation to be Israel. Prof. Halm Garty, head of the department of biological che mistry, is in charge. 6 N I H A A U P D A T E Terry L. Lierman is an NIH manage by plane from countries where polio of directors of the National Coalition ment intern ( 1971-1974) who then is still circulating." for Cancer Research. Ruckdeschel is served as staff director of the U.S. also the medical vice president of the Senate appropriations subcommittee Dr. John Ruckdeschel, a staff Florida division of the American on labor, health and human services. associate at NCI ( 1972-1975) and a Cancer Society. and education, and also as staff visiting scientist ( l 983- 1985), is now director/chief clerk of the U.S. Senate chief executive officer and center Dr. Norman P. Salzman, an NIHAA comminee on appropriations. Afrer director of the H. Lee Moftilt Cancer member, a pioneer in the field of leaving Congress, Lierman founded Center & Research Institute at the molecular virology, and a noted four health and educati on related University of South Florida in Tampa. teacher and mentor died in December companies in the area. and for the Recently he was elected lo the board 1997. His family established a fund at past 15 years has devoted considerable time to charitable and community Dr. Harold R. Stanley, who was assistant chief (senior dental surgeon), service. He recently announced his Clinical Investigations Branch, NIDR in 1949 and 1953-1968. and is now candidacy for the 8tJ1 district congres professor emeritus. Uni versity of Florida College of Dentistry, bas written the sional seai in Maryland, and he ran following letter that is another interesting footnote to medical history. successfully in the Democratic "In your summer 1999 (Vol. 11, No. 2) issue of the NIHAA Update on p. primary on Mar. 7 for the chance to 25, you have a very interesting story under 'A Footnote to Medical History,' challenge U.S. Rep. Constance about Anne S. Miller being the first person in North America to be saved by Morella (R-Md.) in the November penicillin. I have a similar story that might be of interest lo you. 2000 elecLion. His campaign manager In the spring of 1949 I was a dental intern under Dr. Ralph Uoyd al the is Abe Pollin. a business, sports and USPHS Hospital in Baltimore. All of a sudden I began with a cough and community leader in the Washington fever that continued to worsen in a very short period. I was admitted to the meLropolitan area for decades. hospital and diagnosed as having 'Atypical pneumonia.' Nothing was working and my temperature rose to 104-105, one lung was completely no11 Dr. B. Robert Mozayeni, who was at functional and the other was one-tlzird shut down. 1" preparation for my NHLBl (1985- 1987 and 199 1- 1994) is dying my parents came down from Massachusetts, my wife and family were now in private prnctice with Potomac there and my minister. Physician Associates. He is also In desperation, my doctors, Luther Terry (c/1ief of medicine) and his medical director m the Maplewood senior resident Stuart Sessoms, asked if I would consider being treated with Park Place in Bethesda. a 11ew dntg being investigated al NIH called tetracycline. My family and I decided we had nothi11g to lose. In a few hours a team appeared from NIH Dr. Georges Peters, who was at NIH and began to lake blood and throat smears followed by an oral dose of as a clinical associate ( 1966-1968). is tetracycli11e. I ate applesauce lo quench the bad taste and help to retain the now a professor of pediatrics al Brown medication. At tlzat moment Dr. Sessoms said that I was probably the first Universily. He is chairman of the human to receive this experimental drug. National Vaccine Advisory Committee. In 48 hours my temperature had dropped to 101 and my lungs began to Recently in a New York 7J111es article improve. Around the 10th day I was about to be discharged. Not having on polio. he was quoted: " It' one of eaten much during the illness I was asked what I would like. I requested the great triumphs of 20th century my motlier-in-law's Baltimore crab cakes, which the hospital administra medicine. We hope that in the next 5 tion pennitted. to 10 years, polio vaccine will no At discharge, I returned to work but co11ti11ued to have a bitter taste, longer be necessary- similar to the orange stools a11d an itchy anus for at least 6 months. situaLion with smallpox." Later in There may be some discrepancies in this story since it occurred 50 years the article, he said, "The major ago but they possibly could be verified if my medical records are preserved reason for the reluctance to withdraw somewhere. the oral vaccine sooner has been Many years later when Dr. Terry was president of the University of concern about the global village in Pennsylvania, we passed in the Atlanta airport and he still remembered me which we li ve. We're just a few hours and my illness." 8 WINTER 2 0 0 0 the Foundation for the NIH to support promotional text for the Arizona left NIH in 1999 to become director of the Nom1an P. Salzman Memorial Senior Academy (a new retirement the Yan Andel Research lnstitute, Award in Virology. On Nov. 18, 1999, community now under construction Grand Rapids, Mich. in a ceremony at the Cloister, Dr. where J will move into a new town Joanna Shisler, a postdoctoral fellow house next June); 2) About five 2-hour Dr. Robert Young, at NCI ( 1967- in the Laboratory of Viral Diseases. practices each week on a magnificem. L988) . is president of Fox Chase NIAID, received the fi rst annual new electronic organ at our church. As Cancer Center in Philadelphia. He Norman P. Salzman Memorial Award a piano player of pop music by ear. was recently elected first vice presi in Virology, and a pri ze of $2,500. I'm taking classical music lessons with dent of the Ameri can Cancer Society. Por more information about the fund, our new organist.. . ! appreciate both or contact the Foundation for the NIH, 1 your letters, even though the vast new Dr. Marvin Zelen, who was with the Cloister Court. Bethesda, MD 208 14 constructi ons on the NIH campus leave Biometry Branch at NCI ( 1963-1967), or call 30 1-402-53 11. me wondering whether there is any has left his position as chairman of space left for the grass to grow!" Dana-Farber's depanment of biostatis Dr. Richard Schilsky, a clinical tics. He established the department in associate in the NCI Medicine Branch Dr. George Vande Woude, who was at 1977. After a sabbati cal leave, Zelen and the Cl inical Pharmacology NCI as chief or the Laboratory of will return to Dana-Farber in a Branch, Division or Cancer Treatment Molecular Biology ( l 98 l- L983). research capacity. ( 197 1-1 977), is now professor of returned to NCI as director of NCr s medicine and director of the Univer Division of Basic Sciences and sit y of Chicago Research Center. He scientific advisor to NCI director Dr. is also associate dean for clinical Ri chard Klausner ( 1995- L99 9). He research, biological sciences division, University of Chicago Pritzker School Dr. G. Donald Whedon sent the photograph shown below with this of Medicine. Recently he was caption: Dr. Arthur Kornberg (r). Nobel laureate and former chief of appointed to the NCI board of biochemistry. NIAMD. with Dr. G. Donald Whedon (I). at the dedication scientific advisors. He was also of the new Arthur Kornberg Medical Research Building at the University elected to a second 5-year term as of Rochester Medical Cemer in September 1999. chairman of the cancer and leukemia Whedon ex plained in an enclosed note that he and Kornberg had over group B. lapped at NIH for about 6 months but they had known each other before because they were members of the same class. 1941. at University of Dr. Lawrence Shulman, NIH Rochester School of Medicine. emissary for research and director Whedon adds, "Anhur is an emeritus of NlAMS. spoke at the 50th alumnus of NIH. having been chief reunion of his class at the Yale of the Biochemistry Laboratory of University School of Medicine last Nl AMD. He left in 1952 for June in New Haven. He discussed Washingron University at St. Louis progress in recruiting young physi to head the Dept. of Biochemistry. cians to perform clinical research where he was located when he won investigati on. the 'prize.'" He goes on to say that he chinks Albert Siepert, who was the execu they both look prett y good for tive officer at NIH (1947- 1958), wrote (almost) old age. "I'm almost 84, to Calvin Baldwin: "Actually, and, Arthur, 1 th ink, is 83. He is although I am supposed to be in full stiU at Stanford. no longer head of retire ment, my waking hours have biochemi try there. but still active. been consumed by several priori ties: mostl y lecturing on the values of 1) As a volunteer. meeting some medical research." deadlines for writing and editing 9 N I H A A UPDATE Recent NIH Retirees who are also NIHAA Members Letter from NIHAA Preside/If Dr. William l. Gay ro the Members Dr. Erv Baas, NIDDK veterinarian who spent almost 30 years at NCH . has retfred. He ftrst joined NIH as a senior animaJ diseases investigator for the Veterinary Resource Program in the early l 970's and has witnessed a change January 2000 from seeing veterinari ans as enforcers of rules and regulations to being an integral part of the research team. He and his wife, Marilyn, are moving to Richmond. where he wi ll be a part-time clinician in the animal resources Dear NIH.AA Members: division of lhe Medical School of Virginia at Virginia Commonwealth Univer sity ... Stephanie Bursenos, deputy director of lhe Fogarty International Happy New Year. Your association Center. has retired after more than 41 years of government service. She came officers and staff survived Y2K and to NCH in 1983 as a program officer for Europe and then rook on additional the millennium celebrations, and responsibilities for Japan. the USSR. China and Taiwan. She became deputy we Look forward to serving you in director in 1994. Her retirement plru1s include taking courses, involving the year 2000. herself in local politics. and spending time with her grandchildren ... Charles A. Rexroad, known to everyone as "Al'' has retired after a 34-year career The NIHAA has been fortunate spent entirely within lhe walls of Bldg. 10. He worked in various jobs ac the since you last heard from me in CC and was on the staff of the special events secti on and in 1986 was named that a generous alumna. Onie head of the office. Now that he is retired his plans include traveling and Powers Adams. has provided us meshing with his fondness for sports. he has taken a part-time job at a local with the funds to have an extra sporting goods store ... Dr. Melvin L. Spann , associate director for special issue of NIHAA Update and to ized information services at the NLM. recently retired after 35 years of continue our activiti es through the government service from the library where he had worked since 1976 .. . rest of the year. We need to keep Marvin Trusty, NIAAA executive officer. has retired after 38 years of looking for support for our annual service. Plans for retirement include travelling, finishing house projects. more meeting, the Shannon lecture and family activities, and time devoted to the civic association in Rockville and as ocher events, including the an active member of the Baha' i Faith community ... Paul Van Nevel, director newsletter. of the Office of Cancer Communications, NCI since 1974, retired Dec. 31. He had been with the instilllte for 26 years. Van Nevel recently received the Our executive director. Harriet Presidential Rank of Meritorious Executive. Early last year he received an GreenwaJd, has arranged for us award for distinguished service to journalism and mass communications from to have a web site at http:// the University of Wisconsin, Madison, for being a "pioneer in the way www.fnih.org/nihaa.html. Look professionals in the United States and throughout the world communicate for it on your computer. We look about cancer and other health issues." He has started a communications forward to keeping in closer touch consulting service to companies and organizations in 1J1e health fields. with our members through this site and hopefully to recruit more new Clarification: members. In our last issue we wrote in the note about Dr. Samuel Broder that Cetera G enomics and T he lnstitute for Genomic Research Sincerely. (TIGR) were a joint venture. This is not accurate. Dr. Craig Venter left TIGR to found Celera Genomics. TIGR is a not for profit William J. 10 WIN T ER 2 0 0 0 Fifty-five Years Later: A World War II Recollection By D1: John F. Sherman, former NIH deputy director lo early April 1945, elements of the lime. In anotl1er nearby buHding was a Le Harve. Th.e camps bore dle names U.S. Army 89th Infantry Division and row of about four large furnaces, doors of then-popular American brands of the 4th Armored Division confirmed ajar and bones visible inside. The cigarettes. Camp Lucky Strike, the long-held rumors about notorious scene, such as from some movie so largest, was located on a former Gem1an camps iD which Jews, gypsies, hooible as not yet made, continued German airfield and had a capacity of people from occupied countries and with the discovery of a large pile, about 60,000 men. Others were called political dissidents were imprisoned in partially filled with half-burned logs Old Gold, Twenty Grand and Philip large numbers. Much to the surprise intermingled widl human bodies and Morris. and horror of men in the leading railroad rails. (It was here dlat the Of panicular interest co Ille touring components of those units, they had frequently shown photograph of group was a warm greeting by dle two over-run one of the fi rst of those many Generals Eisenhower, Bradley, Patton generation members of a club in the camps during the rapid advance of and others was taken. A copy of iliat town ofYvetot. Over the years dley AUied forces over Ge1many east of the picture is on djsplay at Ille U.S. had salvaged, restored and maintained Rhine Ri ver. This camp was located Holocaust Memorial Museum). a sizable number of WW IT U.S. Army on the outskirts of a smaU German Questioning of a few remaining vehicles. In many instances, both dle town caUed Ohrdruf, a few miles inmates who were still ali ve revealed vehicles and the authentic uniforms of south of the city of Gotha. that only a day or two previously dle club members bore the.Rolling W, the The sight that greeted those U.S. camp guards had rounded up those insignia of Ille 89th Division. Other soldiers was beyond belie f. Inside a wbo were able to walk and forced highlights of the tour included ceremo wire-fenced area were several rows of them out of the camp to the east. nies for fallen comrades at the one-story, dark-colored wooden Word had been received iliat tlle Normandy and Luxembourg military structures. such as might have sheltered American trnops were approaching cemeteri es. German soldiers. Nothing especia.ll y rapidly. Those wbo could not join the Most impressive and dle high-point unusual about them, but whar inunedi rnarcb were summarily shot. Among of Ille tour was a memorial service at ately drew the soldiers' attention was the corpses found in the compound St. Goar in honor of those who had what they saw on the grounds of dtis was at least one former guard who had perished in a combat crossing of the enclave. Scattered in haphazard attempted to hide his identity by Rhine River near dle Loreley Rock. fashion were bodies of many humans dressing in inmate's clothes. Memories returned vividly of tl1e swift dressed in fi lthy, ragged, black-and In October L999, I joined about 50 of river current and Ille steep banks on white striped clothing. Closer exami my World War IT coll eagues as well as either side of the river, making the nation revealed them to be not on ly wives. fri.ends and some adult children crossing under enemy fire especiall y dead but reduced to mere skeleton on a Tour of Remembrance in France hazardous. appearance and most had visible bullet and Germany. l had been a major on Demonstrating that over time some wonnds. As the Americans moved the staff of Division Artillery, 89th attitudes have re flected an increased through tl1e fenced area they were Division, during the unit's engagement sense of tolerance and desire for confronted by more sights that in that conflict, and the site of the peace, units of l:h e American I st increased the initial reaction of Ohrdruf concentration camp was one Armored Division and oft.he German disbelief and horror. Through the open o:f the stops on ow- two-week tour. 5th Panzer Division played prominent doors of the nearest buildings, they The early part of the tour was spent in roles in that ceremony. Later, moving discovered many more skeleton-li ke Normandy where following V-E day, from what had been West Germany bodi es arrayed on tiers of wooden the 89th spent most of Ille remainder into Ille former East Germany. it bnnks. In one structure were still more of that year managing several huge became obvious that even several bodies in the same condi tion, piled tent camps and processing hundreds of years after reuni fication much re like cordwood and sprinkled with a thousands of U.S. troops destined to mained to bring d1e latter up to par white substance that must have been return to the U.S. through the port of with the west. 11 N I H A A U P D A T E In visi1ing the si1e of 1he former concentra1ion camp. I recalled tha1 I and 01hers were, in effecl. ordered to 1our th e camp on th e day following its discovery and before any attempt had been made to alter its appearance. T he American commanders also forced the burgermeister or the town, his fellow officials and their wives to see the camp and its •·exhibits." The Germans had denied any knowledge of the camp or its ex istence. That night following their tour the burgermeister and his wife committed suicide. Little information is now available about Ll1 e camp. After the war ended that section of Germany was a part of the country occupied by the Soviet Union and was later included in East Germany. Apparently the camp in some form was used by the Soviet military and is now the site or a German Army 1raining ground. No Major John Sherman {far r) shown with other soldiers at Camp Lucky Strike in Normandy, in the summer of 1945. physical evidence of the concentration camp remains although members of recollection on one of the 1our buses possible resuscitation. They linally the tour group were able to identify its after the Ohrdruf stop. The speaker. at found one man alive but who was so general locat ion. Not surprisingly. lhe earlier time a junior enlisted man weak and dist11rbed that there was no little apparenlly was documenLed and probably in his late teens, related possibility or communication. Before during the Cold War and the Germans his eyewitness account as one of the he could complete his sto1y on the bus, have shown no evident interest in first into the camp. A long w ith a the speaker was overcome by emotion. auempting to locme sources of lieutenam physician, he was directed Even U1e passage of 55 years could information. When the tour group co move among the corpses to deter not erase the horror of Ll1ose sights. reached th e area, only a civilian and a mine if any might reveal a pu lse for senior enlisted man were available, it being a Sunday. After some negotia tions, they agreed to accompany some What's Your News? members of the group to the area The NIHAA wants to hear from members. Please type or print your note (include avail where it was thought the camp had able photographs), and send to Update at 9101 Old Georgetown Rd ., Bethesda, Md; been located. 20814; or email: [email protected] . The Ohrdruf camp. as ten·ible as i1 Name: (Include NIH affiliation) was. did not approach in size or purpose 1he ex1ermina1ion camps Home Phone: locaiecl eas1 of Germany. Ohrdruf was News: considered a sa1elli1e of Buchenwald and apparently housed inmates working as laborers on some projec1 1he nature or which has never been es tablished. A liuing commentary on what th ose vetcrnns experienced was a 12 WI N TE R 2 0 0 0 Budget, ( co11ti11ued from p. 1) on a one-for-one matching basis to • The N1H director is requested to qualified organizations. contract with an independent board budget cut of 0.38 percent; NIH The National Center for Research group to study the overall security is among the agencies affected by this Resources is slated to receive $75 situation ai the Bethesda campus. reduction but wil\ have flexibility in million for extramural constrnction, an The study shou ld include recom applying the cut, with no program 10 increase or $45 million over FY 1999. mendations regarding the be trimmed by more than 15 percent. The National lnstituce of Environmen appropriate manpower, training According to Sue Quantius, NIH tal Health Sciences is strongly urged to and equipment needed to provide associate director for budget, NfH's study the effects of dioxin and Agent adequate security for NIH em share of the budget cut is in the range Orange in Southeasl Asia. The bill ployees and all visitors to the of 0.55 percent, or a reduction of some contains a number of specific direc campus as well as any recom $98 million. tions affecting OD: mended changes to the current The bill wi.11 resu lt in budget in security policy. creases al all or N !H's 24 institutes and Programs including Minority cenrers, as well as the Office of the Access to Research Careers, • NIH is strongly encouraged to Director. l.t wi ll also boost to nearly Minority Biomedical Research dedicate more resources to autism I 0,000 1.he number of new and Support, Research Centers in research and to intensify these competing research project grants Minority Institutions, and the efforts through the NIH autism supported in FY 2000. The National Office of Research on Minority coordinating committee. Cancer Lnstitute, Nlffs largest, will Health programs should continue ge1 an increase of 14.8 percent to $3.3 to be supported a1 a level com • The National Institute of Diabetes billion, while NBLBJ, the second mensurate wi.th their importance. and Digestive and Kidney Dis larges! institute, will realize a gain of eases and NIAID are commended 14.5 percent to a total of $2 billi.on. Nill is encouraged to pursue for jointly supporting research on The National Human Genome Re research on all types of diabetes. foodborne illness; the institutes search Institute budget is set to ri se by NIH is requested to develop a are encouraged to enhance 25.4 percem. to a total of $337 report co Congress by Mar. 1, research on the reaction of the miUion, and the National Center for 2000. outlining a research agenda gut to foodborne pathogens. Complementary and Alternative for Parkinson's focused research Medicine gels a 37.5 percent increase for the next 5 years, along with The omnibus bill was signed after LO $69 million. The Office of AIDS professional judgment funding eight Continuing Resolutions kepi Research, part of the Office of the projections. unfunded federal agencies operating Director. gets $44.953 million and the beyond the Oct. I start of the new Foundation for NIH is set to receive NIH is urged to establish an Office fiscal year. It keeps NIH on target for of Bio-imaging/Bioengineering $500,000. a congressional effort to double Lhe The omnibus bill directed N1H to and to review tbe feasibility of NIH budget by 2004. transfer $20 mi 11 ion from NlAID to the establishing an Institute of Centers for Disease Control and Biomedical Imaging and Engi Prevention by Jan. LS , 2000, for study neering. The office should of the safety and efficacy of vaccines coordinate imaging and bioengi FY 2001 NIH Budget used against agents of biological neering research activities, both Proposed terror. Nl H must also set aside $20 across NIH and with other federal President Clinton has proposed a million for a new program of chal agencies. NIH must reporr on $ 1 billion. or 5.6 percent. boost for lenge grants - to be funded by 1he progress achieved by this office by NJH in his FY 200 1 budget Public Health and Social Services June 30, 2000. request released Feb. 7. NLH's Emergency Fund - to promote joint total budget would be approxi venlures between NlH and the biotech mately $18.9 billion nex1 fiscal nology, pharmaceu1ical and medical device industries; the program is to be yea r. 13 N I H A A U P D A T E ACD Meeting, ( co111i1111ed from p. 1) Gerald Fischbac h of NINDS and Dr. cooperation that [Vannus has] obvi Steven Hyman of NfMH recom ously been able to incite here is California Dental School; Dr. Norman mended the formation of an "inte exactly what this problem is going to Anderson, director of lhe Office of grated neuroscience research" program need in the future." Behavioral and Social Sciences that could be housed by 2004 in a Attendees also heard from presenters Research, leaves in March for a 200.000-square-foot Neuroscience about planning and budgeting for professorship a1 Harvard University's Center on campus. The new center extramural building projects: Dr. School of Public Health; and Varmus would bring together researchers David Kaufman, president of 1he himself moved on. ending his sixth from several ins1iw1es jncluding Federation of American Societies for year as NIH director 10 Lake the reins NINDS, NIMH, NIAAA, NIDA. Experimental Biology, gave a needs of New York City's Memorial Sloan NIDCD and NIA. assessment for research institutions; Kenering Cancer Center in February. Taking for example the molecule Quantius offered a legislative proposal Also anticipated is the departure of dopamine-which has implications in for NfH 's support of such needs: and Rep. John Porter (R-111.). who will not NINDS's Parkinson's disease research, Dr. Wendy Baldwin, NIH deputy run for reelection. Yarmus hailed NIAAA's and NlDA's drug addiction director for extramural research. Porter-longtime chai r of the House of and reward research, and NIMH's explained the role of NfH funding in Representatives commiuee that emotion and mood disorder research outside construction matters. oversaw NIH-as "one of 1he great Hyman explained, "lt's patently Issues in the News champions of NLH'' and credited him ridiculous to divide investigators who Two other topics 1hat were discussed for being instrumental in acquiring via are interested in the action of this during the ACD meeting coinciden legislation the tremendous prosperit y molecule into different buildings tally were also being covered in the the agency has enjoyed in recent years. even different intellectual universes media that day: NIH had released 1he Construction On Campus and Off by vi m1e of the accident of where we first-ever proposed guidelines for stem divided up the clinical sciences years "[n view of NlH 's prosperity and the eelI research on Dec. I : and the annual ago. It will lead to enormous progress number of projects in progress and meeting of the recombinant DNA both in terms of the basic science. but projected both here and around the advisory commiuee (RAC) was also in terms of the translation of country." Varmus said, '"f thought it scheduled for the next week. The discovery into clinical therapeutics by would be useful to think about how RAC would be reviewing issues bringing these scientists together. We NTH supports construction and related to the death of a young man would li ke to create a model that goes renovation, and what more we ought to taking part in an NJH-supported from molec ule to behavior to clinical be doing. We're developing our 2001 clinical study of gene therapy at the application.'· budget and planning for 2002. This University of Pennsylvania. The Citing the cost of renting off-campus seems like an auspicious time to safety, and successes and failures of lab space coupled with the need for consider whether the ways we cur gene therapy clinical trials, a well as rentl y support infrastructural needs are scientists 10 interact with those doing what oversight roles NIH and the Food similar work. Hyman continued, sufficient, or whether we should be and Drug Administration should have 'There are other benefits that arc less pressing for even greater increases in in the conduct of such studies were all intellectual and lofty and more the amount of money we can supply to concerns slated to be discussed at the financial. There is this broad intellec extramural institutions' constructi on RAC meeting. tual vision. but there is also a very acti vities or 10 projects we can carry ·The NLH is in a difficult situation in practical aspect 10 this.'' out here on campus." tha1 it is not inherently a regulatory think this was the most exciting Updates on several intramural .. r agency." Varmus explained. Regul a thing that l have read about in all the building projects were presented, tion is handled by FDA. he continued. time that I have been involved with including the Clinical Research .. Gene therapy is one of a variety of this group." e111hused Dr. Shirley Center, the Louis Stokes Laboratori es therapeutic modalities, all of which Tilghman, a professor in Princeton Bldg., and the Vaccine Research have risks. NIH continues 10 believe it University"s department of molecular Center. fn addition, a new project was has a very impona111 role in maintain biology and ACD member. "This is proposed to occupy wha1 is currently ing the pub lic discussions of novel reall y spectacular. The spirit of Bldg. 35. Institute directors Dr. developments in gene therapy re- 14 WINTER 2 0 0 0 search," he said. "Recent events require that NIH take a closer look to Kirschstein and Maddox at the Helm ensure that we are doing everything Dr. Ruth Kirschstein has been named acting director of NIH until a pennanenL director that can be done to minimize the is appointed. She has served as depury director si nce 1993 and was also acting director dangers of gene therapy.. .l believe of NIH for 5 months before Dr. Harold Varmus took over in November L993. gene therapy has promise despite the HHS Secretary, Donna E. Shalala, iu her unfortunate events and that we need to announcement of Lhe designation, said take a long tem1 outlook." Kirschstein "brings to her new role a wealth of Health Disparities Addressed experience within Lhe NlH and Lhe Department ... Her proven leadership qualities. administra Another issue that merited special tive abilities and skill in representing the NIH mention in the 2000 appropriation was and HHS to various public and congressional the marked difference in health status constituencies ensure a smooth leadership between minority and majority transition." populations in the U.S. and the world. Kirschstein, a native of Brooklyn, N. Y. "The administration bas taken a very received her B.A. degree in 1947 from Long firm position on reducing disparities Ts land University and her M.D. in 1951 from in health status," Vannus said. "It's Tulane University School of Med.icine. She important that those of us who are interned in medicine and surgery at Kings County Hospital, Brooklyn, and did resi charged with seeing technological dences fo pathology at Providence Hospital, Detroit; Tulane University School of improvements in medicine not Jose Medicine; and the Clinical Center in 1956. From 1957 to 1972. she did vaccine safety sight of the fact that public health research at the Division of Biologics Standards (now the Cemer for Biologjc Evaluation goals are paramount. In the 2000 and Research) of the FDA. In 1974, she was named director of the National Institute of budget, one of our key areas of General Medical Sciences and remained in that position until 1993. She was also actino emphasis is health dispari ties, both 0 associate director or the Offiee of Research on Women's Health (1990-1991) when it domestic and international. There are was first established. She _is the author of more than 70 scientific publications and a more than 50 new initiatives across NIH addressing various aspects of member of the Instituce of Medici.ne and the American Academy of Arts and Science. She received Lhe highest honor for career civiJ servants, the Presidential Rank Award for health disparities." Distinguished ExecuLive.s. NIH is supporting a bi.II i.n Congress Recently Kirschstein announced the appointment of Dr. Yvonne Maddox as acting that would strengthen NIH's Office of deputy director for NIH. Maddox bas been Research on Minority Hea.lth (ORMH) the deputy director of NICHD since January by giving the office grantrnaking 1995. Before joining NICHD, she served in authority, Varmus said. While "the fate of that bill is still unclear," be various positions with NIGMS, including continued, "I will be taking specific acting director of Lhe Minority Access to administrative action before I leave to Research Careers Program and deputy implement many of the ideas within di.rector of the Biophysics and Physiological the legislation. It doesn't include Sciences Program branch. everything in the bill that I'd like to She completed her undergraduate studies at the Virginia Union University in Richmond, see- I can't establish a loan repay ment program or award grantmaking Va. She completed advanced studies in authority-but I can do a number of biology at American University, and received other things that will be in this her doct0rate in physiology and biophysics administrative directive." fron:i Georgetown University, where she served as an assisLant professor and indepen One thing Varmus's di.rective will dent investigator. She has been involved with several DHHS initiatives includino the National Strategy to Prevent Teen Pregnancy and the DHHS Race and Healt; do is activate an annual strategic plan that will be fonuu lated by Disparities initiative. She has received numerous awards including the Presidential institute directors, ORJ\>1H and the Meritorious Executive Rank Award, PHS Special Recognition Award and the NIH NIH di.rector. Director's Award. 15 N I H A A UPDATE Dr. Harold Varmus Leaves NIH: Excerpts from Exit Interview A few days before Varmus left NIH to head Memorial Sloan-Kettering Cancer Center in New York City, he was inteviewed by Rich McManus, editor of the NIH Record and other reporters. McManus wrote a two-part interview that appeared in the Jan. 11 and Jan. 25 issues (http:www.nih.gov/news/NIHRecord/archives/htm). Following are excerpts fro m those articles: Why did you decide to leave now? have one major office in Bldg. I and I involved in clinical research .. .! thjnk Various reasons. One of them is I spend almost all my day in Bldg. I. 1 in general the feeling is that the began to feel it was repetitive ... go co my lab for an hour or so a day, (inu·amural) program is incredibly Second ly. there is a timing of one's but I don' t have my office equipment healthy and that the new buildings are career. To have gone deeply into my there, so I don't settle in. But at going to make it even more so. sixties would have. r think. reduced M emorial Sloan-Kettering, my f'll point co the Vaccine Center as a the chances of my getting another intention is to spend half my day in the particularly exciting accomplishment really good job, and I did want to have hospital executive office and half the becau se we've gouen that center built a really good job. Third, this opportu day next door at my lab in the both physically and intellectually in a nity became available. There have Rockefeller Bldg. very short time. Great people have been oth er things With respect to the been brought in here - certainly Gary that I've heard (N[H) intramural Nabel's recnaitment was a godsend - about. and occa program. l have to and the idea that the intramural sionally even say that from th e lirst program can really. as advertised. inquired about and day I got here, I've respond quite quickly to what was gouen into discus really enjoyed being perceived to be a nationa.I need. sions about, but this in the intramural namely we weren't doing enough to is the first thing that program. I did foster the development of an AIDS seemed LO be very choose wisely, I vaccine, has been responded to in a appealing. and I believe, by placing way that probably could not happen really couldn't put my lab in one of the on this scale anywhere else except this off for another nicer buildings - at N IH. couple of years. I Bldg. 49 and in How involved do you intend to be in think in an ideal choosing co be in the the private sector once you leave world l probably would have left midst of investigators in the Human federal service? maybe a year after the next administra Genome Projecc...being enmeshed in I want to be associated, for th e time tion. assuming that I could stay on and thac network of investigators has been being, with nonprofit ventures. and I they didn't ask for my resignation. very energizing. And we've had a lot am interested in encouraging the But my wife was also interes ted in of collaborative arrangements. I've growth of biotech in New York. One leaving nnd then I find th e draw of a seen though. and heard from many of the things I've spoken about combination of New York and putting inves tigators. that they feel that the elsewhere in the last couple of months cancer research together with cancer esprit de corps has risen, and that the that I think could end up being A) a IOI treatment, and being in a strong seminar programs have improved. A of fun. B) quite stimulating scientifi institu tion with interesting neighbors lot of this I don't take credit for - cally. C) actually economically like Dr. Arnold Levine and the Michael Gottesman has been a beneficial to the state and city of New Rockefeller. all preuy appealing. tremendous director of intramural York is to try to find a location for Can you assess your role, accom research here.. .rve also enjoyed building a kind of science park or plishments and what you've learned watching new buildings go up. and biotech incubator. A place I have in as NIH director and NIH scientist in clinical investigation prosper, to th e mind. and I haven't been shy about the intramural program? point where we're now worried about saying this, is the waterfront in Obviously r mgo ing to have both having too many activities in the Queens. Many of the major institu roles at Memorial Sloan-Keuering, in Clinical Center rather than loo few. tions in New York l'hat I care about are fact my roles there w ill probably be That's all been exciting to me, even on the East River-Sloan-Keuering, more obviously divided because here I though my own lab has not been Cornell, Rockefeller and NYU. Others 16 WI N TER 2 0 0 0 are not that far away. The streets are You have advice for the reorganiza organizations or clusters of organiza crowded, the ri ver is pretty tion of NIH - would you want to be tions that work very effectively open ... There is space over on the on any task force that would deal together and make the whole process riverfront in Queens that is less with that? of running the NIH one that is much expensive and more available, and Sure. But my own view is that the more effective. connected to interesting neighbor kinds of changes that are being If you were around for another hoods. So I envision this little ferry contemplated are. first of all, reason 6 years as NIB director, bow service running back and forth among ably radical. Secondly, they may fly would you improve the intramural these places, and bringing our investi in the face of the interests of advocacy program? gators back and forth (and) seeing not groups and Congress, both of which Part of it is location. I'm concerned for-profit and for-profiL labs that do have been extremely generous to the about having significant components genomics and other technology NIH. I feel that it would be wrong for of our program in less than ideal development and pharmaceutical it to appear that NIH was driving these space, and too far removed from development kinds of things side by changes. NIH is a publicly created centers of activity. I think we're going side, io a way that would be quite institution, and it's been successful for to have tremendous flowering of the attractive to investors. It would be that reason. Any sense that NIH is program as a result of the new Clinical fun. trying to take matters into its own Center and Bldg. SO, but there are still What advice would you give your bands and make it more convenient for outlying groups that worry me. The successor? itself I think could produce some campus up in Bayview (Baltimore) is One is ro continue the budget fight, waves of disgruntlement that would going to become mote self-sufficient; second is to take great advantage of serve the institution very poorly. My as we bring the three components chat the strong advocacy that NIH bas. I've own advice is that at some point, are up there together, they'll have a been saying to both the scientific enlightened members of Congress and nucleus of activiry. I am worried that advocacy groups and the patient and the administration who understand we do have pieces, and sometin1es disease-oriented advocacy groups that some of the difficulties that result from al.most all of certain other programs they need to work better with each having tremendous proliferation of not well organized. One of the most other. NIH. I think, bas done a good institutes and centers should consider promising things that I've strong.ly job working with its scientist constitu asking the National Academy (of supported and have helped to get under encies; I tl1ink it's done an improved Sciences) to set up a commission to way is the concept of having a Neuro job, and at many of the institutes a think, over the course of a couple of science Center on campus, with some splendid job, of working with patient years, about t11e future of the new and renovated buildings in the advocates ...I th ink I was slow to NIH.. .Our budget is soon going to pass Bldg. 35-36 complex that wilJ help to appreciate the importance of develop the $20 billion mark, we have 25 bridge some of the chasms that ing a ldnd of nonsectarian council of institutes and centers, a 11d them will be currently eidst between some of the advocacy individuals of the sort that I more because things never seem to go institutes. even though they do very finally have now with my Council of backwards. As I noted when I first similar tl1ings. Public Representatives ... I've found my came here, when you create new interactions with those folks tremen institutes, it's Like the spring is coming dously useful...I've also tri.ed to out of a little peanut brittle can and remind people of the equity you never stuff things back in. You issues ... the need to be conscious of can't deal with this issue piecemeal health disparities and the need to pay it's very apparent to me that the small attention to the more general applica institutes simply can't operate with the tion (of scientific advances), kinds of efficiencies and carry out some of the tasks the bigger institutes especially as our science becomes Whimisica l artwork announcing the heavily technological and potentially can carry out...I can see an NIH in farewell included a caricature of very expensive. which there are, basically, five or six Varmus biking to his new job. 17 N I H A A UPDATE Update on Gene Therapy Oversight Editor's Note: Almost a decade ago, NIH intramural researchers pioneered two human gene therapy trials. Since. then ~he re ha.ve been some 350 human gene therapy protocols. The death last September of Jesse Gel s in ~er, ~ 18-year-old p~ ti~nt w~th par~al ornithine transcarbamylase (OTC) deficiency, who was enrolled in a study protocol at the Umvers1ty of Pcnnsylvama m Phil ad e lph1~, prompted congressional hearings, media articles and. an FDA freeze on the study in which Gelsinger was enrolled. The NIH recombi nant DNA advisory committee (RAC), held a 3-day meeting at Nm in December to review th~ scientific, ethic.al and overs!gh t q~ es tions. Following is an excerpt of an article from the Jan-Feb. 2000 issue of the NIH Cauzlyst, written by Fran Pollner, managmg editor. The rules and roles of federal agencies involved in overseeing gene therapy experiments are undergoing review and may be revised in the wake of Jesse Gelsinger's death. Specifically, the role of the NIH recombinant DNA advisory commit tee is being revisited, and proposed amendments to the NTH Guidelines for Research Involving Recombi11a111 DNA Molecules (NIH Guidelines) have been published. The harmony or lack of it-between NTH and FDA adverse event reporting requirements in the conduct of clinical trials is also Responding to questions during a news briefing after the first day of the RAC meeting are being scrutinized. (from I), Amy Patterson, director, NIH Office of Biotechnology Activities; Lan a Skirboll, Revisiting the RAC. Before director, NIH Office of Science Polley; Phil Noguchi, director, FDA Division of Cellular vacating the office of NIH director, and Gene Therapies; and Kathryn Zoon, director, FDA Center for Biologics Evaluation and Harold Varmus announced the Research. Nearly all questions centered on FDA's oversight role in the OTC study, formation of a subcommittee of the protocol violations, and FDA's steps to uncover, punish, and prevent irregularities in gene therapy clinical trials. director's advisory group to recom mend further actions NIH might take RAC and ochers involved in gene adverse events to local review bodies to mi nimize adverse events in gene Lransfer studies. "Inm1ediately" is and tbe FDA as well as to NlH and therapy triaJs. Although the group's defined as no later than 15 days from the federal Office of Protection from charge also places the role of the RAC the event A "serious adverse event' is Research Risks. FDA reporting back on the table, Varmus stands by defined as any "expected or unex requirements require the study his actions in 1995 to recast the RAC pected adverse event, related or sponsor (who has presumably been from a quasi-regulatory body with unrelated ro the intervention, occurring informed by the investigator) Lo approval authori ty over every gene at any dose" that resultS in dealh, a immediately report serious and therapy application to a public policy life-threatenfog event, bospitaJ unexpected adverse events to FDA. forum on novel methods in gene admission or prolonged stay, or NIH proceedings are public; FDA therapy clinical trials and thorny disability. proceedings are often closed. issues related to gene therapy. II also rejects recent claims by some During the RAC proceedings, clarified the NIH Guidelines. NIH gene therapy investigators and spon industry representatives accepted the definition of adverse events and sors that human gene transfer proto need for immediate reporting only of investigators' reporting obligations in cols and serious adverse event reports "related and unexpected'" serious a proposed action to amend the NTH are trade secrets. Informed consent adverse events, and some RAC Guidelines, published in the Federal documents would reflect the necessar members voiced skepticism chat they Nov. 22, 1999. The proposal Register ily pubLic nature of RAC discussions could deal meaningfully with reports reaffirms that investigators must report of adverse events. of aJI adverse events. serious adverse evenrs immediately to The NTH Guidelines require the NIH, so NIH may rapidly notify the principal investigator to report serious 18 WIN T ER 2 0 0 0 Science Research Updates Gene Mutation Results in "This is an example of an astute in a mouse's genes better-and modify Missing Teeth clinical observation unveiling a ing the mice to add or subtract a classic pattern of autosomal domi human-like gene with its variations Approximately 20 percent of the nant inheritance, where offspri ng of wi 11 help scientists unlock tile secrets of population are born unable to develop both sexes have a 50-50 chance of these and other human diseases in a a full set of teetb. Although the inheriting a mutated gene and the variable humankind. underlying causes are mostly un disorder associated with it," said known, members of a Houston family D'Souza. ''From tbat point it was a who lack mainly their first and second matter of applying the techniques of NIAMS Launches Projects in molars were found to have a mutation molecular epidemiology and DNA Autoimmunity in a gene called PAX9. This is the first analysis to identify the gene." report of a human disorder linked to The National Institute of Arthritis and PAX9, one of a family of "master" Musculoskeletal and Skin Diseases has genes that help determine body shape Centers To Breed awarded nearly $4 million for new and organ formation during embryo Genetically Variant Mice projects on autoimmune diseases, logical development. This discove11' is conditions in which cJ1e body's immune an important contribution to under To help learn more about how cells mistakenly attack irs own tissues standing the genetics of human tooth human bodies repair their and vital organs. The funds are part of a development and brings scientists a environment-damaged DNA and $30 million allocation from Congress to step closer to someday replicating the control their cells' life cycles, NIEHS bolster research in autoimmuni ty. process. will fund up to five research centers The awards enhance NIAMS' com Scientists m the University of to develop and breed mice with mitment in this area, and involve the Texas-Houston Dental Branch and genetic variations that are more like start-up of nine projects targeted against Baylor College of Medicine discov those of humans in these regards. some 80 serious, chronic, autoimmune ered the PAX9 mutation in a family in The centers will provide t11e special illnesses involving almost every human which congenitall y absent molars were mutant mice for scientists through organ system. documented in members of three out ND-I and to other research "Auroimmune diseases like rheuma generations. programs as well. Many cases of toid arthritis, lupus, scleroderma. The finding, published in the January human disease are caused or crig alopecia areata, and many blistering issue of Na111re Generics, was sup gered by a natural or man-made skin diseases exact a huge toll in human ported by the National Institute of substance in the environment, often suffering and economic costs," said Dental and Craniofacial Research. when an environmental substance NLAMS director Dr. Stephen Katz. The discovery of the PAX9 mutation causes a genetic mutation or a "But we've recently wi tnessed exciting began with Dr. Rena D'Souza disturbance in cell growth. Varia research advances in several of these, associate professor of orthodo~tics, tions in a person's genes make the and we have every intention of pushing directing her students to look for person more, or less, sensitive to our knowledge base further." patterns of missing teeth in their these substances or more, or less, patients. One of these students, able to resist or repair the damage. coauthor Monica Goldenberg, ob Generic variati ons explain why one Are you a life member? If not, served a 13-ycar-old boy missing 14 smoker gels cancer or heart disease you will receive a dues notice from permanent teetJ1. Further investigation from tJiat exposure while another NIHAA this spring. revealed that the father and two smoker doesn 't. Or why some brothers had a similar condition. and members of a family react to environ Dues are an important source of out of 43 family members, 21 were mental substances and develop our income, and we need your determined to have congenitall y asthma, while others do not. NIEHS continued support. Please renew missing molar . said that understanding the variations promptly. 19 N I H A A UPD A TE For Your Information NIH Revises Master Plan NlH has prepared a Master Plan modification for the northwest quadrant of the campus. The Glenn Visits NIH modification originated from che road changes associared with the On Thursday evening, Jan. 27, Sen. John H. Glenn and fellow astronauts Clinical Research Center project. from the Space Shuttle Disc0very, STS-95, visiced NTH to present "home Replacement sites had to be found movies" from their October 1998 scientific research mission. The for four major facilities in the 1995 presentation took place in Mascer Plan. lt also became clear chat rhe main auditotium of the NIH would need a third electrical Natcher Conference Center. power substation. NJ H and NASA are collabo Several alternate sires were evaluated rating on a wide range of to accommodate a day care center. a research areas. The STS-95 patient family guesr house. a parking mission studied body garage. and a fire station. As part of changes that are shared by the process, NTH consulted with astronauts and older people. nearby neighborhood and civic On Friday, Jan. 28. scien organizations as well as the Montgom tists of the STS-95 mission ery County Planning Boar.:d and lhe participated in a symposium National Capital Planning Commis that featured a scientific sion. session about the experiments carried out on their flight. That rook place Final site selection was also endorsed all day in Masur Auditorium, Bldg. 10. by che NIH Community Liaison Council, which is composed of representatives of SlllTOunding commu nities. The Master Plan modification includes the following: Day Care Center. A future child day care facility will be locared just north Ship Ahoy! of Center Drive directly northwest of the CRC. It will be accessible from Continuing Education, lnc., University major circulation routes. A drop-off at Sea is sponsoring, in conjunction with lane is readily situated from the Holland America. a 7-·nightAlaska Master Plan loop road. The plan Cruise starting May 20, 2000, featuring includes playground space that can Dr. C. Everett Koop. accommodate 75-150 chiJdren. The theme is "The Excellence of PEPCO Substation. One-third of the Aging - Design Your Lifestyle for the NIH power demand will be si ruaced in Best Years of Your Life." this quadrant when the CRC and other NIH AA will benefit if we participate. facilities are completed. The substa ll1terested NTHAA members should call tion will be placed on the slope of the 1-800-422-07 11 or email: hill just north of Center Drive near the [email protected] for proposed fire stati on and adjacent to delails. the wooded area in the northwest quadrant The site selection ensures minimal removal of trees and avoids major drainage impacts. Lt will be 20 W I N T ER 2 0 0 0 away from Lhe medical building complex and allows the main under Volunteers Needed to ground elecLri cal feeder lines 10 be Record Scientific Texts placed within the right-of-way of for Students Ce111er Drive. Parking Structure. Six and one-half Recording for the Blind & levels of parking! 850 spaces! The Dyslexic of MeLropolitan Wash parking facility's exterior design will ington (RFB&D) is setting up a adhere Lo the guidelines for architec recording booth in Bldg. 31 for tural materials identilied in the 1995 the conven.ience of N1H employ Master Plan. It will be built on a ees, alumni and neighbors. parce l that is currently being used as a Local students who have visual. surface parking lot nex t to Bldg. I 0. learning or other physical disabili All vehicle access w ill occur from ties urgently need taped versions Back, And To The Future Convent and South Drives using the of their science textbooks. The 1999 perimeter loop road system. Adjacent NTH's Broadcast Services I I Research sidewalks will provide convenient Office is providing studio time to Festival pedestrian access 10 the CC. RFB&D from I 0 a.m. to I p.m. attracted a Fire Station. The new fire station on Tue days and Thursdays. To J record will replace the existing outdated learn more about thi volunteer number. as facility that is not well connected 10 opportunity and to sign up for attendees the new roadways. The planned upcoming orientation sessions crowded station will have approximately 22,000 contacr Chris Smith at 202-244- three square feet of space, including an 8990 or [email protected]. plenary apparatus room and dormitory space. sessions Takeshi Ito of NIMH IL will be built on an existing parking (gene describes his poster. lot to minimize Lrec rem oval. New emergency vehicles will have rapid therapy, transplantation and access 10 the N IH campus road system. imaging); a host of mini-symposia Guest H ouse. This building will be and poster sessions; and a hugb situated on the lawn area south of Technical Sales Association Center Drive and north of th e former vendors show. Research Festival convent. This structure will house 2000 is scheduled for the week of patie111s and th eir families in a 1wo Oct. 9-13. s1ory building that will be residential in scale and detailing, featuring materials and forms compatible with the former convent building. As with the 1995 Master Plan, this NIEHS HQ Renamed to Honor Dr. David Rall amendment provides a guideline for The NIEHS headquaners and laboratory Bldg. I 0 I in Research development if and when funding Triangle Park. N.C.. has been renamed 1hc RaJJ Bldg., in honor of becomes available for any of the former NLEHS director Dr. David Platt Rall. who died Sept. 28 after projects mentioned. Currently, only an automobile collision. NJH and Rep. D avid Obey of Wisconsin the fire station and the electrical recommended the designation, which was approved by HHS. substation arc scheduled to be con Rall was remembered at two memorial services in December. one structed rhi s year. was held at NIH and the other at Nl EHS. The announcement was made by Dr. Ruth Kirschstein at the NJH service. 21 N I H A A UPDATE Dr. Mark. A. Klebanoff was recently Referral, CSR. She comes from the for Complementary and Alternative named director of NICHD's Division of department of applied cellular radiobiol Medicine. He was selected for his Epidemiology, Statistics and Prevent.ion ogy, Armed Forces Radiobiology Research experience in alternati ve therapies and his Research. He has been at NlCHD since Institute, where she was a visiting scientist expertise in clinical evidence, which will 1983 ... Dr. Michael Marti:n has recently ( I989- l994) and a research biologist result in significruit expruision of clinical joined CSR as director of the Di vision of ( 1994-1999) ... Alexander I. Rosenthal research in this field ... Dr. Anne T homas Physiological Systems. He wi.ll coordinate was recently named director of the new recently joined the staff of NINR as clinical and monitor the initial peer review of grant Division of Enterprise and Custom director of the Division of Intramural applications submined to NIH ... Ana Applications for CIT. He came to NIH in Activities and chief. Aeallh Promotion Martinez bas been appointed chief of Lhe 1995 from R.O.W. Sciences, Inc., where Laboratory. She comes to NJNR from newly established Phrumaceutical Affairs be worked as a senior systems analyst ... lndiruia State Un iversiry School of Nursing Branch in NLAID's Division of AlDS ... Dr. Julia Rowe Rowland has been named at Terre Haute ... Esmail Torkashvan Dr. Elizabeth Nabel recently joined director, Office of Cancer Survivorship, recently joined NCRR as a general engineer NHLBI as director of the Clinical NCL. The office is the focal point for in the research infrastruc[ure are:L He is a Research Program in tl1e Division of support of special initiatives aimed at registered professional engineer in the state lntramural Research. She becomes one of investigators who interact with cancer of Maryland who specializes iJ1 administer two directors for NHLBl's intramural survivors. and research programs relevant ing and evaluating construction and research program. Last summer. NHLBI to survivors and their families ... Dr. renovation grants. A[ NCRR. he will work reorganized the division into clinical and Michael Sayre recendy joined CSR as prin1arily on the Research Facilities laboratory research programs. The scientific review administrator of the CDF- Improvement and Animal Facilities reorganization allowed creation of several 1 study section within the cell develop improvement Programs ... Frederick new units includ.ing a Vascular Biology ment and function integrated review group. Walker became the executive officer for Branch, which also will be headed by Prior to joining CSR, he was rui assistant OD on Oct 1. He has a long background in Nabel ... Dr. Richard Nahio has been professor in the department of biochemis human resource management at NIH. named first director of the Division of try, and continues as an adjunct assistruit serving most recently as director, Di vision Extramural Research Training and Review professor in the department of biochemis of Senior ruid Scientific Employment. by the National Center for Complementary try and molecular biology at Johns Office of Human Resource Management ... and Alternative Medicine (NCCAM). He Hopkins University School of Hygiene and Dr. Lawrence Wolfe has been named served as the division's acting director Public Health ... Dr. Arthur Schatzkin NlAID's chief information officer and since early 1999. after becoming the has been selected to head the Nutritional director of the instirute's Office of program officer for NCCAM extramural Epidemiology Branch in the Division of Technology Information Systems. He activities in .1996 ... Dr. Michael Nunn Cancer Epidemiology and Genetics, NCI. comes to NIH from General Services has been appointed scientific review His research focuses OD the nutritional Administration ... Dr. Lawrence Yager administrator of the molecular, cellular. causes and prevention of cancer. He first recently joined the CSR as a health and developmental neuroscience 6 study joined NCI in J984 as a senior staff fellow scientist administrator in the infectious section in CSR. He was a senior staff in tl1e Cancer Prevention Studies Brruich of diseases and microbiology integrated fellow in the Laboratory of Molecular the Division of Cancer Prevention and review group. He comes to CSR from Biology, NIMH ... Christopher J. Control, becomiog a senior investigator in Temple University. Ohlandt was recently named director of 1988 ... Dr. Anne Schaffner, a former the new Division of Customer Support in biologist in the NINOS Laboratory of Honors and Awards CIT. He returns to NIH after working for Neurophysiology, is now a scientific Dr. Arthur A. Atkinson, Jr., sen.ior advisor Microsoft ... Dr. Angela Pattatucci joined review administrator in CSR. In her new in clinical pharmacology to the CC director the CSR as scientific review administrator position, she is managing the peer review and director of the ClinPRAT postdoctoral for two study sections in the AIDS and of research grant applications in the training program, has been named a master related research integrated review group. molecular. cellular, and developmental by tl1e American College of Physicians She recently completed a I-year visiting neuroscience integrated review group ... American Society of lntemal Medicine for professorship at the University of Louis Dr. Marcia Steinberg has joined the CSR his distinguished contributions to internal ville in women's st11dies and psychology ... as chief of the cell development and medicine ... Dr. Robert Balaban delivered Susan Quantius recently was appointed functi.on integrated review group and as the G. Burroughs Mider Lecture on Feb. 2 NIH associate director for budget. She had scientific review administrator of the cell in Masur Auditorium speaking on "Domes been director of federal relations for the development and function 4 study section. tication of the Mitochondrion for Cellular Association of American Universities for 2 Her re.search interests encompass cell Energy Conversion:· Longtime chief of years prior to joining NIH. She replaces biology and biochemistry ... Dr. Stephen NHLBl's Laboratory of Cardi ac Energetics, Francine Lillie. who joined NlEHS ... Dr. E. Straus, chief of the Laboratory of he recently became director of the Labora Narayani Ramakrislman has recently Clinical lnves[igation, NIALD. has been tory Research Program in NHLBI's joined the Division of Receipt and appo.inted director of the National Center Division of Intramural Research ... 24 w N T E R 2 0 0 0 Dr. Leslie Ford, associate director for associate director for extramural affairs. Lister Hill National Center for Biomedical clinical research in NCT's Division of recently received the Career Service to Communications. NLM. is one of 24 Cancer Prevention, received from the Health Psychology Award from the members of the International Society for Association of Community Cancer Centers American Psychological Association's Optical Engineering who were promoted to its Outstanding Achievement Award for health psychology division. She was cited fellow of the society. He was cited .. for "significant efforts in enhancing clinical for her '·contributions to the field of health technical accomplishments and extensive research through the NCrs Community psychology and behaviora.I medicine contributions in the areas of imaging Clinical Oncology Program and her research and to the division..... Dr. processing. document image understand leadership in the Breast Cancer Prevention Richard Klausner, NCI director, received ing, and biomedical image databases" ... Trial'" ... Dr. Phillip G-Orden was pre the 12th Donald Ware Waddell Award from Dr. Maria Turner, chief of the Dermatol sented the American Diabetes the Arizona Cancer Center, Tucson, Ariz. ogy Branch Consultation Service. NCJ, Association's Albert Renold Award for a The award is presented annually to a basic received the Everett C. Fox Memorial career distinguished by outstanding or clinical investigator who has made Lecture Award of the American Academy achievemems in the training of diabetes outstanding contributions to cancer of Dermatology recently. After her researchers and his efforts "to preserve che research ... Dr. Edward Lakatta, chief of lecture. entitled ··Medical Dermatology ls integrity of basic research during times of NlA's Laboratory of Cardiovascular Alive and Well," she was presented with a fiscal constraint and to strengthen Science, was recently coawarded the 1999 commemorative plaque and a $ I0.000 mechanisms for research training and Novartis Prize for Geronto1ogical Research check ... Dr. Weidong Wang, head of the career development in diabetes.'" He has with Dr. Pau.I Baltes of the Max-Planck transcription remodeling and regulation stepped down as NIDDK director and will Institute for Educational Research in unit al NlA's Laboratory of Genetics. continue to work as head of the Diabetes Berlin. His research emphasizes how the recently received the Ellison Medical Branch ... Dr. Robert Hoover, director of cardiovascular system is altered by aging Foundation New Scholar in Aging Award . the NCI Epidemiology Program, was ... Bill Leonard, a producer in NLM 's The $200,000 award provides 4 years of presented the Distinguished Service Award Audiovisual Program Development support to conduct basic biological by DES Action USA, for hi s research Branch. has been selected for membership research in the field of aging. Wang is benefiting DES-exposed individuals ... Dr. in the "Silver Circle" by the Washington. characterizing a novel protein complex Alice Horowitz, a health educator in D.C. chapter of the National Academy of involved in_.ile premature aging disease NIDCR"s Health Policy. Analysis and Television Arts and Sciences. The Silver Werner syndrome at NlA's Gerontology Development Branch, recently received the Circle was established in 1987 to honor Research Center in Baltimore ... Dr. Koji Distinguished Service Award from the media professionals for their outstanding Yoshinaga, NJCHD health science American Association of Public Health contributions to the D.C. television administrator. has received the 1999 Dentistry. She was honored for her industry ... Dr. G. Reid Lyon. chief of Distinguished Service Award from the .. excellent and distinguished service" to NlCHD's Child Development and Society for the Study of Reproduction. public health dentistry ... Frances Behavior Branch. recently received the The award acknowledges his contributions Humphrey Howard, special assistant to Kingsbury Center 60th Anniversary Award to the reproductive biology community the associate director, Division of for his "critical leadership of scientilic through work as an investigator, adminis Extramural Programs. NLM. has received inquiry in mentRI development and trator and ·'facilitator of scientific the Institute of International Education's learning,. and for his own research efforts exchange:· He was the first researcher to Duggan Award. She was hailed for the in reading development and reading invescigate the effecLS of nicotine on significant contribULions she has made disorders ... Dr. Barbara Sonies, chief of pregnancy. toward increasing understanding and ties the speech-language pathology section and between citizens of the U.S. and those of director of the ultrasound oral pharyngeal other nations ... Dr. Muriel Kaiser imaging laboratory of the department of Five Elected to IOM Kupfer, chief of the Ophthalmic Genetics rehabilitation medicine, CC. received the Five NIH employees were among and Clinical Services Branch. NEl, highest award. the HONORS. bestowed the 55 people newly elected to the recently received a Lifetime Achievement upon its members by the American Institute of Medicine of the National Award from the Cystinosis Foundation for Speech-Language Hearing Association. Academy of Sciences: Dr. Kenneth her work in describing and treating that The award recognized her work in Fischbeck, chief of NrNDS's disease ... Dr. Albert Z. Kapikian diagnosis of swall owing and swallowing Neurogenetics Brnnch: Dr. Patricia recently received a doctor of science. disorders that raised the area of dysphagia Grady. NINR director; Dr. Richard honoris ccmsa degree from his alma mater management to a respected position within Bodes. NIA director. Betsy Queens College in recognition of his medicine ... Dr. Constantine A. Stratakis, Humphreys. assistant director for ouistanding scientific contributions in the head of the unit on endocrinology and health services research information. fields of epidemiology, virology and genetics of NICHD's Developmental and deputy associate director for vaccinology. I-le also delivered on Nov. 16 Endocrinology Branch, has received the library operations. NLM: and Dr. the Kinyoun Lecture, on "Development of first annual International Award for Daniel Weinberger. chief of the a Rotavirus Vaccine for the Prevention of Excellence in Published Clinical Research Clinical Brain Disorders Branch in Severe Diarrhea in Infants and Young ... Dr. George Thoma, chief of the NCMH's intramural research program. Children,. ... Dr. Miriam F. Kelty, NIA Communications Engineering Branch. 25 w N T E R 2 0 0 0 Dr. Leslie Ford, associate director for associate director for extramura l affairs, Lister Hill National Center for Biomedical cli nical research in NCI's Division of recently received the Career Service Lo Communications. NLM. is one of 24 Cancer Prevention. received from the Health Psychology Award from the members of the lntemational Society for Association of Community Cancer Ccmers American Psychological Association's Optical Engineering who were promoted to its Outstanding Achievement Award for health psychology division. She was cited fellow of the society. He w:is cited "for "significant efforts in enhancing clinical for her "contributions to the lield of health technical accomplishments and extensive research through the NCl's Community psychology and behavioral medicine contributions in the areas of imaging Clinical Oncology Program and her research and to the division" ... Dr. proces ing. document image understand leadership in the Breast Cancer Prevention Richard Klausner, NCI director, received ing, and biomedical image databases'' ... Trial" ... Or. Philli p Gorden was pre the 12th Donald Ware Waddell Award from Dr. Maria Turner, chief of the Dern1atol sented the American Diabetes the Arizona Cancer Center. Tucson, Ariz. ogy Branch Consultation Service. NC I. Association's Albert Rcnold Award for a The award is presented annually to a basic received the Everert C. Fox Memorial career distinguished by outstanding or clinical investigator who has made L~cture Award of the American Academy achievements in the training of diabetes outstanding contributions to cancer of Dem1atology recently. After her researchers and his efforts ··to preserve the research ... Or. Edward Lakntta, chief of lecture, entitled ''Medical Dernmtology Is integrity of basic research duri ng times of NIA's Laboratory of Cardiovascul ar Alive and Well ,'' she was presented with a liscal constraim and to strengthen Science. was recently coawarded the 1999 commemorative plaque and a $I 0,000 mechanisms for research training and Novanis Prize for Gerontological Research check ... Or. Weidong Wang, head of the career development in diabetes." He has with Dr. Paul Balles of the Max-Planck transcription remodeling and regulation stepped down as NlDDK director and will Institute for Education~! Research in unit at NIA's Laboratory of Genetics, continue to work as head of the Diabetes Berlin. His research emphas izes how the recentl y received the Ell ison Medical Branch ... Dr. Robert Hoover, director of cardiovascular system is altered by aging Foundation New Scholar in Aging Award. the NCI Epidemiology Program. was ... Bill Leonard, a producer in NLM's The S200.000 award provides 4 years of presented the Distinguished Service Award Audiovisual Program Development support to conduct basic biological by DES Action USA, for his research Branch, has been selected for membership research in the field of aging. Wang is benefi ting DES-exposed ind ividuals ... Dr. in the "Silver Circle" by the Wash ington, characterizing a novel protein complex Alice Horowitz, a hea lt h educator in D.C. chapter or the National Academy of involved in Ire premature aging disease NIDCR's Health Policy. Analysis and Television Arts and Sciences. The Silver Werner syndrome at NIA's Gerontology Development Branch. recently received the Circle was established in 1987 to honor Research Center in Baltimore ... Dr. Koji Disti nguished Service Award from the media professionals for tJ1eir outstanding Yosbinaga, NlCHD health science American Association of Publi c Health comributions to the D.C. television administrator. has received the 1999 Dentistry. She was honored for her industry ... Or. G. Reid Lyon. chief of Distinguished Service Award from the "excellent and distinguished service" to NICHD's Child Development and Society for the Study of Reproduction. public health demistry ... Frances Behavior Branch, recently received the The award acknowledges his contributions Hum1>hrey Howard, special assistant to Kingsbury Center 60th Anniversary Award to the reproductive biology community the associate director. Division of for his '·critical leadership of scienti fic through work as an investigator. adminis Extramural Programs. NLM, has received inquiry in mental development and trator and "facilitator of scientific the lnstitute of Lnternmional Education's learning" and for his own research efforts exchange." He was the lirst researcher to Duggan Award. She was hailed for the in reading development and reading investigate the effecLS of nicotine on signi ficant contributions she has made disorders ... Dr. Barbara Sonics, chief of pregnancy. toward increasing understandi ng and ties the speech-language pathology section and between citizens of the U.S. and those of director of the ullrasound oral pharyngeal other nations ... Dr. Muriel Kajscr imaging laboratory of the department of Five Elected to IOM Kupfer, chief of the Ophthalmic Genelics rehabilitation medicine, CC, received the Five NIH employees were among and Clinical Services Branch, NEl, highest award, the HONO RS. bestowed the 55 people newly elected to the recentl y received a Lifeti me Achievement upon its members by the American Institute of Medicine of the National Award from the Cystinosis Foundation for Speech-Language Hearing Association. Academy of Sciences: Dr. Kenneth her work in describing and treating that The award recognized her work in Fischbeck. chief of NINDS'i. disease ... Or. Albert Z. Kapikian diagnosis or swallowing and swallowing Neurogenetics Branch; Dr. Patricia recently received a doctor of science. disorders th at raised the area or dysphagia Grady. N!NR director: Dr. Richard '1011oris ca11sa degree from his alma mater management lo a respected position withi n Hodes. NIA director; Betsy Queens College in recognition of his medicine ... Dr. Constantine A. Stratakjs, Humphreys, assbtant director for outs1anding scientific contributions in the head of the unit on endocrinology and health ~ervices research information, fields of epidemiology. virology and genetics or NIC HD's Developmental and deputy associate director for vncci nology. He also delivered on Nov. 16 Endocrinology Bn111ch, has received the library operations. NLM: and Dr. the Kinyoun Lecture, on "Development of lirst an nual International Award for Daniel Wein berger. chief of the a Rotavirns Vaccine for the Prevention or Excellence in Published Clinical Research Clinical Brain Disorders Branch in Severe Diarrhea in Infants and Young ... Or. George Thoma, chief or the NIMH's intramural research program. Children" ... Dr. Miriam F. Kelty, NIA Communications Engineering Branch. 25 W I NTER 2 0 0 0 to Washington from Iowa and worked for the Health Sciences and NIH. and Gail RosweU Park Memorial Institute for NIMH. From 1971-1975, he was deputy .Jacoby, 50, chief of planning at NIA, cancer research and treatment in Buffalo director of NlAAA and after leaving along with their 13-year-old daughter, ( 1970- 1985). He was an early member of NlAAA, he continued to work in alcohol Atira. died Nov. 26 as a result of injuries U1e National Cancer Advisory Board and abuse education until his retirement in sustained in an airplane crash in Newark. chaired the National Prostatic Cancer 1991 ... Dr. Richard Feinberg, a retired N.J. He was professor and director, Project. While in New York slate, his NINOS scientist, died Nov. 28. He was Division of Health Services Administration research group discovered prostate-specific the chief. visua l abnormalities section, in at USUHS. An expert in health services antigen (PSA). Recentl y he was clinical the perinatal project at NlNCDS. He had management and policy, he was deputy professor of urology at the University of worked at the institute from 1966 to 1979 director and director of the Office of Washington and research director of the ... .Janet L. Fitzwater, 79, the retired chi ef Medical Applications of Research at NIH Pacific Northwest Cancer Foundation in of surgical nursing services at the CC, died ( 198 1-1988). She was director of the Seattle ... Robert Johnson Nash, 70, a of Alzheimer's disease Oct. 24 in Rich Office of Planning. Analysis, and Evalua Washington architect who designed mond. She worked at NlH for 18 years, tion, and headed NlA"s ongoing effons to churches, public buildings and schools in beginning in 1953 and was a captain in the prioritize and evaluate it s research the metropolitan area, died of cancer Dec. PHS. She held patents for surgical program ... Dr. Melvin Kahn, a clinical 5 at his home in Fort Washington. He services and contributed articles to nursing professor of medicine. Mount Sinai School designed the ambulatory care research and clinical journals. After she retired, she of Medicine. and attending cardiologist at facility at NlH ... Dr. Daniel NaU1ans, 71. was director of the Washington Home and Mount Sinai Hospital, died in New York a Johns Hopkins University molecular taught nursing at Catholic Un iversity and City. In the mid-19SO's. Kahn was a biologist who shared the 1978 Nobel prize Montgomery Coll ege ... Dr. Clair L. clinical associate at NIH in cardiology and for medicine for research in molecular Gardner, 83. died at his home in Grants renal disease ... Dr. Jerome Irving work, died of leukemia Nov. 16 at his Pass. Oregon, on Oct. 12. He served as Klcinerm:rn, 75, a pathologist and lung home in Baltimore. He was a clinical acting director of NIDR ( 1975-1976) and specialist who helped develop nati onal associate at NCI in the mid- l 9SO's ... also as director of extramural programs. health standards for workers, died in an Eleanor O'Donoghue Nealon, 59. He retired in 1981 after 26 years in the automobile accident on Aug. 6 in Arcadia. director of NCI"s Office of Liaison PHS ... Dr. Dezider Grunberger, 77, a Fla. He was an Nll-1 advisory committee ActiviLies, died of metastalic breast cancer cancer researcher and professor emeritus member ... Audrey B. Lcnderking, 86, a Oct. 22 nt her home in Bethesda. She of biochemistry. molecular biophysics and retired nurse at NlH, died of congestive joined NCI in 198 1 as a speech writer and public health at the Columbia University heart failure Dec. 6 at Warren Memorial formed the liaison office in 1994. She also College of Physicians and Surgeons. died Hospital in Front Royal. Va. She worked was involved with the formation in 1997 of of colon ca ncer on Aug. 7. Hi s research as a pediatric nurse and retired from the 1hc Director's Consumer Liaison Group. focused on chemical carcinogens and th e child research brnnch in 1974 ... Francis NCI has established the Eleanor Nealon mechanisms by which they cause cancer. Joseph Miller, 86. an NIH systems analyst Extraordinary Communication Lecture In 1964, after worki ng in Prague, he came ( 1972-1978), died of congestive heart Series to honor her memory ... Dr. Robert 10 NIH to work and left in 1968, when he fa ilure on Dec. 13 at lnova Cameron Glen H. Parrott, 76, a pediatrician and vi rology began a long association with Columbia's Care Center in Reston. After retiring, he researcher who ran Children's Hospital in Comprehensive Cancer Center ... William participated in tournaments sponsored by Washington D.C. for 3 decades. died of a Cassel Hanson, Jr., 82. a retired security the U.S. Masters Swimming program ... stroke at his home in Highland, Md. From force member ( 1950- 1978) at NIH, died of Dr. Irving Louis Miller, 79, a genetics 1954 to 1956, he did virus research at congestive heart failure July 29 at research scientist at NIH ( 1982-1992), NIH, while serving in the PHS, in the Woodside Center Nursing Home in Silver died of cardiopulmonary arrest July 27 at Laboratory of Clinical Lnvestigation. Spring ... Virginia Thomas Harter, 72, an Cherrydale Nursing Home in Arlington ... NIAID ... Ruth Boyer Peck, 9 1, who NIH employee who relircd in 1994, died Floro Moore, a superv isor in the Division reti red in July 1973 after 16 years as a Sept. 29 at the NIH clinic after a heart of Nursing at the CC ( 1957- 1965), died science writer with NINOS. died of attack. She was secretary to the director of Sept. 19 in Texas of complications from pneumonia Sept. 17 at the Friends Nursing NfMH for 21 years before retiring ... heart disease. She was also a nurse officer Home. While at NIH. she received awards Rosemary Healy, 83, a registered nurse with the rank of commander in the PHS. for a series of NfH neurology publications who worked at NIH, died of heart disease After sbe left NIH she served in a surgical for laymen called "Hope Through Dec. 19 at the Montgomery Village Care unit that had a tour of duty in Vietnam ... Research"' ... Donna Phillips. a retired and Rehabilitation Center in Gaithersburg Louise E. Moore, 75, a nurse who also NEI employee, died Oct. 10, after a two ... Cnrolyn Doe Herber t, 60, a former worked as an interpreter at Nl~, died of year battle with cancer. She retired on registered nurse at NlH. died of' a cerebral cancer Sept. 15 at her home in Palm Bay, May 2 1. 1999, because of illness. She hemorrhage Jan. 3 at Montgomery General Fla .... Dr. Gerald Murphy, 65. secretary began working at NE! on Nov. 30. 1969. in Hospital. She worked at NIH as an general of the International Union Agai nst the admi nistrative office, arriv ing as one of occupati onal medicine and employee Cancer (UICC) and past president of the the institute's first employees ... Dr. health nurse in the mid- l 960's and I970's American Cancer Society, died Jan. 2 1 Clinton C. Powell who was at NIH ( 1946- ... Dr. ltzhak 0 . .Jacoby, 53, who worked after a heart attack while allending the 1964) lastly as the director of NIGMS, at tJ1e Uniformed Services Universi ty of meeting in Israel. Murphy directed the died of multiple myeloma in Redding. 27 N I H A A UPDATE Calif., on Oct. l I. Jn 1954, he came to 72. a retired registered nurse who worked and NlMH. She was a member of the NIH where he served successively in the for NIH in the I 970's, died Dec. 4 at her NIDA's AIDS behavioral subcommittee CC, NCI and DRG, evenrually becoming home in Bethesda. She had leukemia ... and NIH's commitree of behavioral and chief of the Division. In 1961 he was Dr. Sydney E. Salmon, 63, a cancer social science of transmission and named assistant director at NlAID. He researcher and founder of the Arizona prevention of HIV infection ... Dr. was appointed chief of the Division of Cancer Center in Tucson, died Oct. 13 of Sydney Udenfriend, 8 l. a forn1er NIH General Medical Sciences, becoming pancreatic cancer at hi s home in Tucson. biochemist who made contributions 10 director of the new institute on Jan. 30, Early in his career, he was a special fell ow srudies of amino acids, peprides and 1963. He served until I 964 when be left to in hematology and immunology at NIH. biogenic amines. died Dec. 29 in Atlanta. become associate coordinator of medical In 1991. he was named to the National Ga., following heart surgery. Before and health sciences at University of Cancer Advisory Board ... Benno coming to NIH in 1950, he had worked California ... Elizabeth Mary Hayes Schmidt, 86. a pioneering venture with DrS. Jan1es Shannon and Bernard Quinlan, 8 1, a former secretary at NJH, capitalist who was also an advocate for tbe Brodie al the Goldwater Laboratory, New died Oct. 6 at her home in Silver Spring of federal government's war on cancer, died Yo(k University. He was chief of the renal failure. She worked as a secretary at of heart failure on Oct. 21 at his home in Laboratory of Chemical Biochemistry, NIH from the late 1950's to the .late New York City. Ln 1970 as a member of NHI. He left NTH in 1968 to become L960's. She helped make her birth town in the National Panel of Consultants he was director of the Roche Institute for Ireland, Wexford, the sister city of involved in the shaping of the National Molecular Biology in Nutley. N.J .... Anne Annapolis ... Dr. David Platt Rall, 73, a Cancer Act of 1971 . He was appointed by Udoff died on Nov. 9. She worked in OD cancer researcher who simultaneously President Nixon to bead the President's at NIH ... Dr. Eric M. Wagsbal, 54. a headed both NlEHS and the National Cancer Panel and helped NCI secure its retired [ntemist, died of renal cell cancer Toxicology Program. died Sept. 28 in first substantial appropriation: $LOO Dec. 20 at the CC. After a post-residency Bordeaux, France. as a result of injuries million in L972. He was also the chairman fellowship in gastroenterology ac Johns suffered in an automobile accident. He of Memorial Sloan-Kettering Cancer Hopkins Hospital, he served in the PHS al joined NCI in 1954 and his early research Cenrer Boards of Overseers and Managers. NIH as a researcher at NCI in the mid- led, among other things. to methods for He was an acknowledged leader in both 197o·s ... Ur. Hans Waine, 92. an expert preventing the spread of leukemia to the tbe public and private sector efforts in in rheumatology. died Dec. 5 at a nursing brain. Meanwhile, he became increasing.ly biomedical research ... Dr. Paul B. Sigler, home in Stamford, Conn. Prior LO interested in the dilemma that anti-cancer 65. a mol.ecular biologist and biochemist becoming a physician. Waine received a drugs. in the doses needed to be effective. who studied organic structure at Yale doctorate in history in Gennany and tend to be higW.y toxic and may predispose University. died of a heart attack Jan. I I. worked as a journalist in Berlin. He was patients who are successfully treated for a He had worked briefly at NrH after chairman of grants at N1AMD ... Jean S. first cancer to develop a later malignancy. receiving a doctorate in biochemistry at Willis, 79, a secretary at NIH in the That kindled his interest in using animal Cambridge. England in l 968 ... Elizabeth 1960's, died Jan. l8 of cancer at Suburban research to predict toxic effects in patients Daley Snow, 67, a librarian and medical Hospital. After NTH. she worked as a and in systematically exploring the impact indexer at NLM, died of liver failure Aug. secretary to members of the board of the of environmental chemicals on health. 13 at her borne in Vero Beach, Fla. She Washington Star newspaper until it closed This made him a logical choice to head joined NLM in 1983 and continued to do in 1981 ... Dorothy C. Windham, 74, a NIEHS. He was director of the National work for NLM even after 1992 when she retired NIH executive assistam. died of a Toxicology Program when it was head retired and moved to Florida ... Tolbert pulmonary embolism Aug. I at Suburban quartered at NTEHS. He had been a Lee Strong, Jr., 50, a printing specialist Hospital. She worked at NIH ( 1960-1977) member of the NIHAA board of directors for 21 years with the printing procurement as executive assistant 10 the director of ... Ann E. Rathbone, 87. a secretary at section of the Office of Research research. She had been an active church NTH, died Sept. 27 at Shady Grove Serv.ices's Reprographic Communications leader and a community vol.unteer ... Dr. Hospital in Rockville after a heart attack. Branch, died on Nov. 26 of cancer. He Geraldine Woods, 78. former chairman of She worked at NlAID in the 1970's ... began his governmenr career in 1969 as an the Howard University board of trustees. George Ray, Sr., 53. a longtime Nrn administrative aide in the White House. died of cancer Dec. 27 in Los Angeles. employee who was also an African After being promoted 10 staff printer there. She maintained a relationship with NLH as Methodist Episcopal pastor, died Jan. 25 at be joined NIH in 1978 as a printing a special consultant (1969-1987) on the Malcolm Grove Medical Center after a specialist ... Dr. S. Susan Su, a National development and implementation of heart attack. He spent tbe past 28 years at Opinion Research Center senior research research, training and fellowship NIH where he was an engineering scientist whose field of research included programs in biomedical sciences at technjcian in the contracts department and drug abuse ·and AIDS prevention. died of minority i.nstitutions. an equal employment opportunity ovarian cancer Sept. 2 at a hospital in Los specialist. In addition to his work at NIH. Angeles. Al the time of her death, she was in he was involved in his church and tJ1e leader of long-term studies on drug use Mrs. Mary Calley Bartman made a working in tbe community to help people. and HIV risk behavior that was supported contribution to NLHAA in memory of He also drove a yellow taxicab for more by NIDA. She also served on grant Cpt. Janet Fitzwater. than 25 years ... Loraine Bishop Royal, application review committees for NIDA 28 WINTER 2 0 0 0 · NIHAA 2000 BOARD BALLOT PLEASE TEAR OUT AND RETURN WITH YOUR VOTE ln accordance with the bylaws of Lhe Nff!AA, alumni members of the association are to elect one-third of lhe board of Lhe association. The nominating commillee, appoimed by President William r. Gay, has nominated the alumni members listed below. Each has agreed to serve on the board of directors if elected, occupying posiLions on th e board left open by expiring terms of ol'flce of present members. Alumni members may vote for four (4) of these nominees. However, associate members (current NIH employees) are not eligible to vote in this election. Please vote for up to four (4) and return your ballot to the NIHAA office by April IS. Nominees Last NIH Affiliation D Dr. W. Emmett Barkley* Director, Division of Safety, OD D Dr. Rita Colwell Member, NIH Advisory Councils/Committees D Dr. Murray Eden* Chief, Biomedical Engineering, NCRR D Dr. James Ferguson Special Expert, NLM D Dr. Peter Frommer Deputy Director, NHLBI D Mr. Benjamin Fulton Executive Officer, NICHD D Dr. Samuel Greenhouse* Epidemiologist, NIMH D Dr. Joseph Handler Scientist, NHLBI D Dr. Irwin Kopin ScienList, NINDS D Dr. James F. O'Donnell Director, Office of Extramural Programs, OD D Dr. Lawrence Shulman* Director, NIAMS D Dr. Robert E. Stevenson NCI Virologist D Ms. Joan Topalian Executive Officer, ORS D Mr. Paul Van Nevel Director, Office of Cancer Communications, NCI *CURRENT BOARD MEMBERS WHO ARE ELIGIBLE FOR A SECOND TERM. 29 WINTER 2 0 0 0 NIH Retrospectives: 5 Decades of History outbreak arose from a single introduc Limes wi thin the limi ts established by tion of virus, affording an unusual NTH and B/l/D policy. The NlH opportunity for identifying the precise flexitime policy was developed as a time limits of virus activity in each result of experiments here and at other community. federal agencies. In order for the Winter 1950 program to work at NIH, arri val and departure preferences, rotation of Building 12 is now completed. It schedules with coworkers, and will provide maintenance, overhaul coordination of attendance at meetings and scorage facilities for NIH vehicles, arc essential ... Dr. Earl R. Stadtman, and general storage space {ll now has chief of the Laboratory of Biochemis been converted to office and machine try, NHLBI, was awarded the National space for data processing and com Winter 1970 Medal of Science. the highest honor puter operations Work is continu I ... that the federal government accords to ing on the CC construction site that On Dec. 18, 1969, Dr. Jesse this country's scientists and engineers. was begun in November 1948. In Steinfeld was confirmed as Surgeon Since 1959, when the medal was January Lhe superstructure began to General of the Public Health Service. established, live of the recipients have rise with wooden forms for pouring the He succeeds Dr. William H. Stewart been NIH scientists. reinforced-concrete walls set up. who retired ... Ors. Harry M. Meyer, Jr., and Paul D. Parkman, pediatricians in the Division of Biologics Standards, have been awarded the 1969 Parellls Magazine Medals for "outstanding TheNli Record ... _____ .. service to children" because of their ·· -. contribution lo mbella research. They ·- - Winter 1960 developed the first attenuated vi rus Winter 1990 strain, HPV-77 for rubella vaccines, ln January the NIH Record and NIH which is presently being used in Dr. Loujs W. Sullivan. secretary of Calendar of £11e111s offices moved nationwide immunization programs. Health and Human Services, has from Bldg. T-19 to Bldg. I, Rooms approved the long-awaited merger of 209-A and 209 ... Seventy-five "Old the Division of Research Resources Timers" who have worked at ~IH for and the Division of Research Services, over 12 years met informal ly on Jan. 7. a new organization named the National Among those present, James E. Center for Research Resources Phillips, Laboratory Aids Branch, (NCRR). Dr. Roben A. Whitney, Jr. DRS, was senior in length of service. Summer1980 has been named director of the new His 39 years with NIH extend back to center. He was director of DRS since the days when the Hygienic Labora The President's fiscal year 1981 November 1985 and director of ORR tory, forerunner of NIH, was located al budget request for NIH is $3.58 1.5 since October 1988, when NIH 25th and E Streets in Northwest million, a net increase of $138.9 proposed the merger ... The new Washington ... Outbreaks of Asian million over the 1980 comparable National Center of Human Genome innuenza on St. Paul Island and SL budget of $3,442.6 million ... Flex Research (NCHGR), formerl y the Lawrence Island in the Bering Sea ible and compressed work sched ules at Office of Human Genome Research were inves ti gated by scien ti sts of the NfH have been auLhorized by Dr. under the NIH director, will now be Arctic Health Research Center. Alaska Donald S. Fredrickson, NIH director. equivalent to other NIH inslitutes in its Department of Health, and NIAfD's Employees will be able to select and authority to award grants and plan and Rocky Mountain Laboratory. Each vary their starting, lunch and quining direct scientific research. 31