SEAFOOD ZOOMER

Seafood Zoomer

3HSWLGHOHYHOLGHQWLĆFDWLRQRIVHDIRRGVHQVLWLYLW\

1(866) 364-0963 www.vibrant-wellness.com 1360 Bayport Ave. Ste. B [email protected] San Carlos, CA 94070

Page 1 of 16 Vibrant Wellness | 1360 Bayport Ave, Ste B. San Carlos, CA 94070 1(866) 364-0963 | [email protected] | www. vibrant-wellness.com

Final Report Date: 10-19-2018 16:24 Specimen Collected: 11-30-2015

Accession ID: 1512010000 Specimen Received: 12-01-2015 00:00

LASTLAST NAME NAME FIRSTFIRST NAME NAME MIDDLEMIDDLE NAME NAME DATE OF BIRTHGENDER GENDERDATE OF PHYSICIANBIRTH ID ACCESSION ID

TESTNAME PATIENT MALE 1996-10-22 1512010000

PATIENT PROVIDER

Name: PATIENT TESTNAME Practice Name: Test Client, MD Date of Birth: 1996-10-22 Provider Name: Internal2 Test Client2, MD (999999) Gender: Male Phlebotomist: Age: 22 Street Address: 999999 PRACTICE STREET AVE City: SAN CARLOS Telephone #: 000-001-0002 State: CA Street Address: 1021 HOWARD AVENUE SUITE B Zip #: 94404 City: San Carlos Telephone #: 666-666-6662 State: CA Zip #: 94070 Fax #: 111-222-0000 Fasting: FASTING No. of hours: 12.0 For doctor's reference

Vibrant Wellness LvrѴ;-v;7|oru;v;m||o‹o†";-=oo7,ool;uķ|o_;Ѵr‹o†l-h;_;-Ѵ|_‹Ѵb=;v|‹Ѵ;-m77b;|-u‹1_ob1;vbm 1omv†Ѵ|-|bom‰b|_‹o†u_;-Ѵ|_1-u;ruoˆb7;uĺ|bvbm|;m7;7|o0;†v;7-v-|ooѴ|o;m1o†u-];-];m;u-Ѵv|-|;o=_;-Ѵ|_-m7 ‰;ѴѴŊ0;bm]ĺ

The Vibrant Seafood Zoomer bv-m-uu-‹o=1ollomѴ‹1omv†l;7v;-=oo7-m|b];mv‰_b1_o==;uvˆ;u‹vr;1b=b1-m|b0o7‹Ŋ|oŊ -m|b];mu;1o]mb|bomĺ$_;r-m;Ѵbv7;vb]m;7|o-vv;vv-mbm7bˆb7†-ѴĽv]-m7]v;mvb|bˆb|‹|o|_;v;-m|b];mv-||_; r;r|b7;Ѵ;ˆ;Ѵĺ Interpretation of Report:$_;v†ll-u‹u;rou|ruoˆb7;7=ou";-=oo7,ool;uѴbv|v|_;v;|o=v;-=oo7|o0;-ˆob7;70-v;7om |_;1-Ѵ1†Ѵ-|;7u;v†Ѵ|vĺm|_;7;|-bѴ;7u;rou|ķ|_;|;v|u;v†Ѵ|vo=-m|b0o7‹Ѵ;ˆ;Ѵv|o|_;bm7bˆb7†-Ѵruo|;bmv-u;1-Ѵ1†Ѵ-|;70‹ 1olr-ubm]|_;-ˆ;u-];bm|;mvb|‹o=|_;bm7bˆb7†-Ѵruo|;bm-m|b0o7‹|o|_-|o=-_;-Ѵ|_‹u;=;u;m1;ror†Ѵ-|bomĺ!;=;u;m1; u-m];v_-ˆ;0;;m;v|-0Ѵbv_;7†vbm]ƐƖƑ_;-Ѵ|_‹bm7bˆb7†-Ѵvĺ$_;u;v†Ѵ|v-u;7bvrѴ-‹;7-vovb|bˆ;ķo7;u-|;ou;]-|bˆ;ĺ ovb|bˆ;u;v†Ѵ|bm7b1-|;v|_-|‹o†_-ˆ;-mbm1u;-v;7u;-1|bˆb|‹|o|_;-m|b];m‰b|_u;vr;1||o|_;u;=;u;m1;u-m];ĺo7;u-|; v;mvb|bˆ;u;v†Ѵ|bm7b1-|;v|_-|‹o†_-ˆ;-lo7;u-|;u;-1|bˆb|‹|o|_;=oo7-m|b];m‰b|_u;vr;1||o|_;u;=;u;m1;u-m];ĺ;]-|bˆ; oumov;mvb|bˆb|‹u;v†Ѵ|bm7b1-|;v|_-|‹o†_-ˆ;-Ѵo‰u;-1|bˆb|‹|o|_;=oo7-m|b];m‰b|_u;vr;1||o|_;u;=;u;m1;u-m];ĺ(b0u-m| †|bѴbŒ;vruorub;|-u‹=Ѵ†ou;v1;m|-m-Ѵ‹vbv‰_b1_bv7;vb]m;7|o-vv-‹vr;1b=b1|o|-Ѵ]Őv†01Ѵ-vv;vƐķƑķƒķƓő-m7|o|-Ѵ]Őv†01Ѵ-vv;v ƐķƑő-m|b0o7b;vĺ$_;1Ѵ-vvb=b1-|bomo=ovb|bˆ;|oo7;u-|;|o;]-|bˆ;7;mo|;v|_;Ѵ;ˆ;Ѵo=-m|b0o7‹u;-1|bˆb|‹7;|;1|;7|_uo†]_ |_bv-m-Ѵ‹vbvĺ

$_;(b0u-m|);ѴѴm;vvrѴ-|=oulruoˆb7;v|ooѴv=ou‹o†|o|u-1h-m7-m-Ѵ‹Œ;‹o†u];m;u-Ѵ‰;ѴѴm;vvruo=bѴ;ĺ$;v|bm]=ou";-=oo7 ,ool;ur-m;Ѵbvr;u=oul;70‹(b0u-m|l;ub1-ķ-1;u|b=b;7Ѵ-0ŲĹƏƔ ƑƏƕѶѶƏƖĺ(b0u-m|);ѴѴm;vvruoˆb7;v-m7l-h;v -ˆ-bѴ-0Ѵ;|_bvu;rou|-m7-m‹u;Ѵ-|;7v;uˆb1;vr†uv†-m||o|_;$;ulvo=&v;]u;;l;m|Ő|_;Ş$;ulvŞőomb|v‰;0vb|;-| ‰‰‰ĺˆb0u-m|Ŋ‰;ѴѴm;vvĺ1olĺ‹-11;vvbm]ķ0uo‰vbm]ķouo|_;u‰bv;†vbm]|_;u;rou|ou‰;0vb|;ou-m‹v;uˆb1;vķ‹o†-1hmo‰Ѵ;7]; |_-|‹o†_-ˆ;u;-7ķ†m7;uv|oo7ķ-m7-]u;;|o0;0o†m70‹|_;v;|;ulvĺ=‹o†7omo|-]u;;|o-11;r||_;v;|;ulvķ‹o†v_-ѴѴmo| -11;vvķ0uo‰v;ķou†v;|_;u;rou|ou‰;0vb|;ĺ$_;v|-|;l;m|vbm|_bvu;rou|_-ˆ;mo|0;;m;ˆ-Ѵ†-|;70‹|_; oo7-m7 u†] 7lbmbv|u-|bom-m7-u;omѴ‹l;-m||o0;Ѵb=;v|‹Ѵ;1_ob1;v=ouro|;m|b-Ѵubvhlb|b]-|bomĺѴ;-v;1omv†Ѵ|‹o†ur_‹vb1b-mņ7b;|b|b-m =oul;7b1-|bomķ|u;-|l;m|ķouѴb=;v|‹Ѵ;l-m-];l;m|ĺ$_bvruo7†1|bvmo|bm|;m7;7|o7b-]mov;ķ|u;-|ķou1†u;-m‹7bv;-v;ĺ

PleaseNote -,WLVLPSRUWDQWWKDW\RXGLVFXVVDQ\PRGLĆFDWLRQVWR\RXUGLHWH[HUFLVHDQGQXWULWLRQDOVXSSOHPHQWDWLRQZLWK \RXUSK\VLFLDQEHIRUHPDNLQJDQ\FKDQJHV7RVFKHGXOHDQDSSRLQWPHQWZLWK9LEUDQW&OLQLFDO'LHWLWLDQV SOHDVHFDOO7ROO)UHH866-364-0963.

Page 2 of 16 Vibrant Wellness | 1360 Bayport Ave, Ste B. San Carlos, CA 94070 SeafoodZoomer 1(866) 364-0963 | [email protected] | www. vibrant-wellness.com

LASTLAST NAME NAME FIRSTFIRST NAME NAME MIDDLEMIDDLE NAME NAME DATE OF BIRTHGENDER GENDERDATE OF PHYSICIANBIRTH ID ACCESSION ID

TESTNAME PATIENT MALE 1996-10-22 1512010000

INTRODUCTION

Seafood, ZKLFK LQFOXGHV YDULRXV VSHFLHV RI ĆVK DQG VKHOOĆVK FUXVWDFHDQ DQG PROOXVN  LV D SULPH VRXUFH RI KLJKTXDOLW\ SURWHLQ 6HDIRRG LV KLJK LQ YLWDPLQV DQG PLQHUDOV EXW ORZ LQ FDORULHV WRWDO IDW DQG VDWXUDWHG IDW &RQVXPSWLRQRIVHDIRRGKDVEHHQOLQNHGWRQXPHURXVKHDOWKEHQHĆWV

:KLWHĆVKVXFKDVKDGGRFNDQGFRGDUHYHU\ORZLQIDWDQGFDORULHVZKLFKFRPELQHGZLWKRLO\ĆVKULFKLQRPHJD IDWW\DFLGVVXFKDVPDFNHUHOVDUGLQHVIUHVKWXQDVDOPRQDQGWURXWFDQKHOSWRSURWHFWDJDLQVWKHDUWGLVHDVHDV ZHOODVKHOSWRGHYHORSVWURQJERQHVDQGWHHWK6KHOOĆVKDUHSDUWLFXODUO\ULFKLQ]LQFZKLFKLVHVVHQWLDOIRUKHDOWK\ VNLQDQGPXVFOHVDVZHOODVIHUWLOLW\6HDIRRGFDQSURYLGHHVVHQWLDOQXWULHQWVIRUGHYHORSLQJLQIDQWVDQGFKLOGUHQ

'HVSLWHWKHQXWULWLRQDOEHQHĆWVERWKĆVKDQGFUXVWDFHDQVKHOOĆVKDUHDPRQJWKHHLJKWPRVWFRPPRQDOOHUJHQLF IRRGVGHVLJQDWHGE\WKH)RRG$OOHUJHQ/DEHOLQJDQG&RQVXPHU3URWHFWLRQ$FW )$/&3$ 

,Q FUXVWDFHDQV WKH SURWHLQ Tropomyosin LV WKH PDMRU DQWLJHQ UHVSRQVLEOH IRU LQJHVWLRQUHODWHG UHDFWLRQV 7URSRP\RVLQEHORQJVWRWKHIDPLO\RIDFWLQĆODPHQWELQGLQJSURWHLQVZLWKGLIIHUHQWLVRIRUPVWKDWFDQEHH[SUHVVHG LQ PXVFOH DQG QRQPXVFOH WLVVXHV $ FRPSOH[ RI WURSRP\RVLQ DQG WURSRQLQ UHJXODWHV WKH FDOFLXP VHQVLWLYH LQWHUDFWLRQRIDFWLQDQGP\RVLQ7KHDQWLJHQLFLW\RIWURSRP\RVLQZDVFRQĆUPHGLQVL[VSHFLHVRIFUXVWDFHDQVEODFN WLJHU SUDZQ NXUXPD SUDZQ SLQN VKULPS NLQJ FUDE VQRZ FUDE DQG KRUVHKDLU FUDE E\ LPPXQREORWWLQJ DQG WKH RYHUDOOVHTXHQFHLGHQWLW\VKRZHGPRUHWKDQKRPRORJ\

Arginine kinase (40 kDa) LV DQRWKHU DQWLJHQ ZKLFK KDV EHHQ LGHQWLĆHG LQ SUDZQ NXUXPD SUDZQ  VKULPS ZKLWH VKULPSJXOIVKULPS&KLQHVHVKULPS DQGFUDEVSHFLHV PXGFUDEVQRZFUDE 

Sarcoplasmic reticulum Ca-binding protein (20 kDa)LVDQRYHOFUXVWDFHDQDQWLJHQH[WUDFWHGIURPEODFNWLJHUVKULPS DQGLGHQWLĆHGLQZKLWHVKULPSDQGVQRZFUDE6DUFRSODVPLF&DELQGLQJSURWHLQLVDQLQYHUWHEUDWH()KDQGFDOFLXP EXIIHULQJSURWHLQWKDWIXOĆOOVDVLPLODUIXQFWLRQLQPXVFOHUHOD[DWLRQDVYHUWHEUDWHPDMRUDQWLJHQSDUYDOEXPLQ

,Qmyosin light chainZDVLGHQWLĆHGDVDQDQWLJHQLQZKLWHVKULPSDQGEODFNWLJHUSUDZQ2YHUDOOLQGLYLGXDOV ZLWKIRRGVHQVLWLYLW\WRRQHNLQGRIFUXVWDFHDQDUHXVXDOO\DGYLVHGWRDYRLGDOOW\SHVRIFUXVWDFHDQIRRGV,QGLYLGXDOV ZLWKVHQVLWLYLW\WRLQVHFWVVXFKDVFRFNURDFKRUPRWKVPD\DOVRUHDFWWRFUXVWDFHDQV7KH$WODQWLFFRGZDVWKHĆUVW PRGHOIRUVWXG\LQJĆVKDQWLJHQV

Parvalbumin (12 kDa)LVDJO\FRSURWHLQWKDWEXIIHUVFDOFLXPGXULQJPXVFOHUHOD[DWLRQ3DUYDOEXPLQUHSUHVHQWVWKH PDMRU FOLQLFDO FURVVUHDFWLYH ĆVK DQWLJHQV ZLWK KXPDQ VHTXHQFH KRPRORJ\ UDQJLQJ IURP  $V WKH SDUYDOEXPLQVDUHVLPLODULQDOOĆVKVSHFLHVLQGLYLGXDOVUHDFWLYHWRRQHĆVKDUHOLNHO\WRUHDFWWRDUDQJHRIGLIIHUHQW ĆVKVSHFLHV$GGLWLRQDOO\ĆVKVHQVLWLYLW\LVQRWWREHFRQIXVHGZLWKDWR[LFUHDFWLRQWRKLVWDPLQHLQVSRLOHGĆVK VFRPEURLGĆVKSRLVRQLQJ 

Anisakis simplex (herring or whale worm)LVWKHPRVWZHOOVWXGLHGĆVKHU\SURGXFWFRQWDPLQDWLQJSDUDVLWHHOLFLWLQJ FOLQLFDOVHQVLWLYLW\UHVSRQVHV7RGDWHHLJKW$QLVDNLVVLPSOH[DQWLJHQVKDYHEHHQGHVFULEHGDWWKHPROHFXODUOHYHO $QLVWR$QLV VL[RIWKHVHDUH(6GHULYHGWZRDUHVRPDWLFLQRULJLQDQGQRQHDUHDVVRFLDWHGZLWKWKHFXWLFOHRI WKHZRUP

:KLOH IRRG DOOHUJ\ LV DQ LPPHGLDWH ,J(PHGLDWHG LPPXQH UHVSRQVH IRRG VHQVLWLYLW\ LV XVXDOO\ D GHOD\HG ,J*PHGLDWHG LPPXQH UHVSRQVH WKDW LV IUHTXHQWO\ RYHUORRNHG RU PLVGLDJQRVHG 'HWHFWLRQ RI ,J* DQG ,J$ DQWLERGLHVWRSRVVLEOHVHDIRRGDQWLJHQVFDQEHSUHGLFWLYHRIDQHHGWRFKDQJHQXWULWLRQDOLQWDNH LQFRQVXOWDWLRQ ZLWKDGLHWLWLDQ DQGFDQUHGXFHWKHULVNRIGHYHORSPHQWLQWRPRUHVHULRXVKHDOWKFRQFHUQVORQJWHUP

Page 3 of 16 Vibrant Wellness | 1360 Bayport Ave, Ste B. San Carlos, CA 94070 SeafoodZoomer 1(866) 364-0963 | [email protected] | www. vibrant-wellness.com

LASTLAST NAME NAME FIRSTFIRST NAME NAME MIDDLEMIDDLE NAME NAME DATE OF BIRTHGENDER GENDERDATE OF PHYSICIANBIRTH ID ACCESSION ID

TESTNAME PATIENT MALE 1996-10-22 1512010000

Positive Moderate Negative IgG IgA IgG IgA

Oyster Parasite Crab Lobster Shrimp and Prawn Anisakis simplex Salmon and Trout Cod and Pollock Clam Parasite Anisakis simplex Mussel

Snail

Scallop

Squid

Octopus

Flatfish (Plaice, Sole, Flounder)

Monkfish

Mackerel and Tuna

Sardine, Herring, Pilchard

Anchovies

Bass

Carp

Catfish

Bream

Hake

Pufferfish

Croaker

Tilapia

Swordfish

Page 4 of 16 Vibrant Wellness | 1360 Bayport Ave, Ste B. San Carlos, CA 94070 SeafoodZoomer 1(866) 364-0963 | [email protected] | www. vibrant-wellness.com

LAST NAME FIRST NAME MIDDLE NAME GENDER DATE OF BIRTH ACCESSION ID LAST NAME FIRST NAME MIDDLE NAME DATE OF BIRTH GENDER PHYSICIAN ID TESTNAME PATIENT MALE 1996-10-22 1512010000

LIFESTYLE CONSIDERATIONS

Avoid seafood

6KHOOĆVKLVUDUHO\DKLGGHQLQJUHGLHQWEXWLWPD\EHLQĆVKVWRFNRUVHDIRRGćDYRULQJ&RPSDQLHVDUH UHTXLUHG WR ODEHO DQ\ SURGXFW WKDW FRQWDLQV VKHOOĆVK RU RWKHU IRRGV WKDW RIWHQ FDXVH IRRG VHQVLWLYH UHDFWLRQVEXWWKHUHJXODWLRQVGRQRWDSSO\WRPROOXVNVVXFKDVFODPVR\VWHUVDQGVFDOORSV

,IĆVKRUVKHOOĆVKLVSUHVHQWLQDIRRGSURGXFWLWLVXVXDOO\OLVWHGRQWKHSDFNDJLQJ+HUHLVDOLVWRIVHDIRRG WRDYRLGLI\RXDUHVHQVLWLYHWRĆVKRUVKHOOĆVK

Crustaceans FUDEOREVWHUVKULPSSUDZQ :KLWHĆVK FRGSODLFHVROHFROH\KDGGRFNSROORFNPRQNĆVK )DWW\ĆVK PDFNHUHOWXQDVDUGLQHVDQFKRYLHVVDOPRQSLOFKDUGVKHUULQJWURXW Mollusks FODPVPXVVHOVR\VWHUVVQDLOVVFDOORSVVTXLGRFWRSXV

Replacements for seafood for a balanced diet

6HDIRRG LV DQ H[FHOOHQW VRXUFH RI SURWHLQ YLWDPLQV DQG PLQHUDOV 7KH )RRG 6WDQGDUGV $JHQF\ UHFRPPHQGVWKDWZHHDWDWOHDVWWZRSRUWLRQVRIĆVKDZHHNZLWKDWOHDVWRQHRIWKHVHEHLQJIDWW\ĆVK ZKLFKLVSDUWLFXODUO\KLJKLQHVVHQWLDORPHJDIDWW\DFLGV+RZHYHULI\RXDUHVXIIHULQJIURPVHDIRRG VHQVLWLYLW\ LW LV LPSRUWDQW WR GLVFRYHU ZKLFK VHDIRRG LQ SDUWLFXODU \RX UHDFW WR DQG WR PDNH VXUH \RX LQFOXGHVXLWDEOHIDWW\DFLGUHSODFHPHQWVLQ\RXUGLHWVXFKDV

Coconut oil Walnuts Tofu Brazil nuts Sesame butter Hazelnuts Pumpkin seed butter Pecans Eggs Avocado Olive oil Spinach and other leafy greens Flaxseed oil

Page 5 of 16 Vibrant Wellness | 1360 Bayport Ave, Ste B. San Carlos, CA 94070 SeafoodZoomer 1(866) 364-0963 | [email protected] | www. vibrant-wellness.com

LASTLAST NAME NAME FIRSTFIRST NAME NAME MIDDLEMIDDLE NAME NAME DATE OF BIRTHGENDER GENDERDATE OF PHYSICIANBIRTH ID ACCESSION ID

TESTNAME PATIENT MALE 1996-10-22 1512010000

6KHOOĆVK&UXVWDFHDQV

Crab

&UDELVDPHPEHURIWKHFUXVWDFHDQIDPLO\$OOFUDEVSHFLHVDUHORZLQIDWDQGDJRRGVRXUFHRISURWHLQDVZHOODVPLQHUDOV OLNHVHOHQLXP)RRGVHQVLWLYLW\WRFUDELVUHODWLYHO\FRPPRQ&RRNLQJGRHVQRWUHPRYHWKHVHQVLWLYLW\DVVRFLDWHGDQWLJHQV 0DMRU SURWHLQV LQYROYHG LQ FUDE VHQVLWLYLW\ DUH WURSRP\RVLQ DUJLQLQH NLQDVH DQG VDUFRSODVPLF UHWLFXOXP &DELQGLQJ SURWHLQZKLFKDUHYHU\VLPLODULQDZLGHUDQJHRIFUXVWDFHDQIRRGV

Current Result Previous Result Reference Range

IgG 2.8 0.4 ≤2.0 0.1 2.0 4.0 6.0

IgA 1.3 1.0 ≤2.0 0.1 2.0 4.0 6.0 Specific Reactivity: Freshwater crab IgA, Red king crab IgA

Shrimp & Prawn

6KULPS DQG SUDZQ DUH ERWK PHPEHUV RI WKH FUXVWDFHDQ IDPLO\ 7KHUH DUH QR PDMRU GRFXPHQWHG GLIIHUHQFHV EHWZHHQ SUDZQVDQGVKULPSLQWHUPVRIQXWULWLRQDOYDOXH7KH\ERWKDUHULFKLQSURWHLQVDQGYLWDPLQVDVZHOODVWKHFDURWHQRLG DVWD[DQWKLQDQDQWLR[LGDQWDQGDQWLLQćDPPDWRU\QXWULHQW7KH\UDQNDVJRRGVRXUFHVRIRPHJDIDWW\DFLGVDQGFRQWDLQ WZRVSHFLĆFRPHJDIDWW\DFLGV(3$DQG'+$0DMRUSURWHLQVLQYROYHGLQVKULPSVHQVLWLYLW\DUHWURSRP\RVLQDUJLQLQH NLQDVH VDUFRSODVPLF UHWLFXOXP &DELQGLQJ SURWHLQ DQG P\RVLQ OLJKW FKDLQ ,Q DGGLWLRQ VRPH DGYHUVH UHDFWLRQV WR VKULPSSUDZQPD\QRWLQYROYHDFWXDOIRRGVHQVLWLYLW\EXWUDWKHUUHDFWLRQWRVXOĆWHSUHVHUYDWLYHVXVHGWRSURWHFWWKHVKHOI OLIHRIWKHVKULPSSUDZQSURGXFWV Current Result Previous Result Reference Range

IgG 0.4 0.3 ≤2.0 0.1 2.0 4.0 6.0

IgA 0.9 0.3 ≤2.0 0.1 2.0 4.0 6.0

Lobster

/REVWHUV DUH PHPEHUV RI WKH FUXVWDFHDQ IDPLO\ /REVWHU LV D ORZFDORULH SURWHLQ VRXUFH DQG ULFK LQ SKRVSKRURXV PDJQHVLXPSRWDVVLXPDQG%YLWDPLQV)RRGVHQVLWLYLW\WROREVWHULVUHODWLYHO\FRPPRQZLWKPLOGV\PSWRPV&RRNLQJGRHV QRWUHPRYHWKHOREVWHUDQWLJHQLFSURWHLQV0RVWOREVWHUVHQVLWLYLW\VHHPVWRLQYROYHDPXVFOHSURWHLQWURSRP\RVLQZKLFK LVYHU\VLPLODULQDZLGHUDQJHRIFUXVWDFHDQIRRGV

Current Result Previous Result Reference Range

IgG 1.4 0.8 ≤2.0 0.1 2.0 4.0 6.0

IgA 2.9 0.3 ≤2.0 0.1 2.0 4.0 6.0 Specific Reactivity: American lobster IgA, Chinese spiny lobster IgA

Page 6 of 16 Vibrant Wellness | 1360 Bayport Ave, Ste B. San Carlos, CA 94070 SeafoodZoomer 1(866) 364-0963 | [email protected] | www. vibrant-wellness.com

LASTLAST NAME NAME FIRSTFIRST NAME NAME MIDDLEMIDDLE NAME NAME DATE OF BIRTHGENDER GENDERDATE OF PHYSICIANBIRTH ID ACCESSION ID

TESTNAME PATIENT MALE 1996-10-22 1512010000

6KHOOĆVK0ROOXVN

Clams

&ODPLVDFRPPRQQDPHIRUVHYHUDONLQGVRIELYDOYHPROOXVNV7KHUHDUHRYHUGLIIHUHQWHGLEOHVSHFLHVRIFODPVLQWKH ZRUOG &ODPV DUH D ORZ IDW KLJK SURWHLQ VHDIRRG FKRLFH ZLWK DQ DERYH DYHUDJH DPRXQW RI KHDOWKIXO PLQHUDOV VXFK DV VHOHQLXP]LQFLURQDQGPDJQHVLXPDQG%YLWDPLQVOLNHQLDFLQ'XHWRWKHSURWHLQFRQWHQWGLIIHUHQFHWKHLQGLYLGXDOVZKR DUHVHQVLWLYHWRFUXVWDFHDQVPD\QRWQHFHVVDULO\UHDFWWRFODPV

Current Result Previous Result Reference Range

IgG 0.2 1.9 ≤2.0 0.1 2.0 4.0 6.0

IgA 0.9 1.3 ≤2.0 0.1 2.0 4.0 6.0

Mussel

0XVVHOLVDFRPPRQQDPHIRUPHPEHUVRIVHYHUDOIDPLOLHVRIELYDOYHPROOXVNVIURPVDOWZDWHUDQGIUHVKZDWHUKDELWDWV 0XVVHOVRIIHUVHYHUDOKHDOWKEHQHĆWV7KH\DUHKLJKLQ%YLWDPLQVDQGSURYLGHDUHDGLO\DEVRUEHGVRXUFHRIPDQ\RWKHU %YLWDPLQVYLWDPLQ&DPLQRDFLGVDQGYLWDOPLQHUDOVLQFOXGLQJLURQPDQJDQHVHSKRVSKRUXVSRWDVVLXPVHOHQLXPDQG]LQF 0XVVHOVKDYHPRUHRPHJDIDWW\DFLGVWKDQDQ\RWKHUVKHOOĆVK,QDGGLWLRQVRPHDGYHUVHUHDFWLRQVWRPXVVHOVPD\QRW LQYROYHDFWXDOIRRGVHQVLWLYLW\EXWUDWKHUVKHOOĆVKSRLVRQLQJ$YRLGHDWLQJPXVVHOVLIWKH\ZHUHKDUYHVWHGLQRUQHDUDUHG WLGHZKLFK LQGLFDWHV D KLJK SRSXODWLRQ RI GLQRćDJHOODWHV UHGGLVKEURZQ PLFURRUJDQLVPV WKDW FDQ LQIHFW PXVVHOV DQG FDXVHVKHOOĆVKSRLVRQLQJ

Current Result Previous Result Reference Range

IgG 1.3 1.0 ≤2.0 0.1 2.0 4.0 6.0

IgA 1.0 1.2 ≤2.0 0.1 2.0 4.0 6.0

Oyster

0DQ\EXWQRWDOOR\VWHUVEHORQJWRWKHVXSHUIDPLO\2VWUHRLGHD3DFLĆFR\VWHUVDUHQDWXUDOO\RQHRIWKHPRVWQXWULWLRQDOO\ ZHOOEDODQFHGRIIRRGV7KH\DUHORZLQIDWFDORULHVDQGFKROHVWHUROLQDGGLWLRQWREHLQJKLJKLQSURWHLQLURQRPHJDIDWW\ DFLGVFDOFLXP]LQFDQGYLWDPLQ&%HFDXVHR\VWHUVDUHELYDOYHPROOXVNVVHQVLWLYLW\WRR\VWHULVPRVWFRPPRQO\DVVRFLDWHG ZLWK VHQVLWLYLW\ WR RWKHU ELYDOYHV HJ FODPV PXVVHOV DQG VFDOORSV  DV ZHOO DV GLVWDQWO\ UHODWHG PROOXVNV HJ VQDLOV RFWRSXVDQGVTXLG  Current Result Previous Result Reference Range

IgG 5.3 0.8 ≤2.0 0.1 2.0 4.0 6.0

IgA 1.9 1.1 ≤2.0 0.1 2.0 4.0 6.0 Specific Reactivity: Olympia Oyster IgG

Page 7 of 16 Vibrant Wellness | 1360 Bayport Ave, Ste B. San Carlos, CA 94070 SeafoodZoomer 1(866) 364-0963 | [email protected] | www. vibrant-wellness.com

LASTLAST NAME NAME FIRSTFIRST NAME NAME MIDDLEMIDDLE NAME NAME DATE OF BIRTHGENDER GENDERDATE OF PHYSICIANBIRTH ID ACCESSION ID

TESTNAME PATIENT MALE 1996-10-22 1512010000

Snail

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

Current Result Previous Result Reference Range

IgG 1.2 1.5 ≤2.0 0.1 2.0 4.0 6.0

IgA 1.0 0.8 ≤2.0 0.1 2.0 4.0 6.0

Scallops

6FDOORSV DUH D FRVPRSROLWDQ IDPLO\ RI 3HFWLQLGDH DQG 3HFWLQRLGHD ELYDOYHV IRXQG LQ RFHDQV DQG QHYHU LQ IUHVK ZDWHU 6FDOORSVDUHDORZIDWVHDIRRGFKRLFHWKDWLVDJRRGVRXUFHRISURWHLQDQGVRPHPLQHUDOVDQGYLWDPLQV6FDOORSVDUHDOVRORZ LQPHUFXU\VRWKDWWKH\FDQEHLQFOXGHGLQWRDVHDIRRGEDVHGGLHWRQDUHJXODUEDVLV'XHWRWKHSURWHLQFRQWHQWGLIIHUHQFH WKHLQGLYLGXDOVZKRDUHVHQVLWLYHWRFUXVWDFHDQVPD\QRWQHFHVVDULO\UHDFWWRVFDOORSV

Current Result Previous Result Reference Range

IgG 1.2 1.5 ≤2.0 0.1 2.0 4.0 6.0

IgA 0.8 1.6 ≤2.0 0.1 2.0 4.0 6.0

Other mollusks

$OWKRXJKVTXLGDQGRFWRSXVKDYHQRVKHOOWKH\DUHFHSKDORSRGVWZRFRPPRQO\FRQVXPHGPROOXVNV6HQVLWLYLW\WRVTXLGLV DVVRFLDWHGZLWKVHQVLWLYLW\WRRWKHUFHSKDORSRGVVXFKDVRFWRSXVDQGSRWHQWLDOO\RWKHUPROOXVNV Current Result Previous Result Reference Range

Squid IgG 0.8 0.2 ≤2.0 0.1 2.0 4.0 6.0

Squid IgA 0.3 1.7 ≤2.0 0.1 2.0 4.0 6.0

Current Result Previous Result Reference Range

Octopus IgG 0.5 0.1 ≤2.0 0.1 2.0 4.0 6.0

Octopus IgA 1.6 1.3 ≤2.0 0.1 2.0 4.0 6.0

Page 8 of 16 Vibrant Wellness | 1360 Bayport Ave, Ste B. San Carlos, CA 94070 SeafoodZoomer 1(866) 364-0963 | [email protected] | www. vibrant-wellness.com

LASTLAST NAME NAME FIRSTFIRST NAME NAME MIDDLEMIDDLE NAME NAME DATE OF BIRTHGENDER GENDERDATE OF PHYSICIANBIRTH ID ACCESSION ID

TESTNAME PATIENT MALE 1996-10-22 1512010000

)LVKå:KLWHĆVK

Cod and Pollock

&RGEHORQJWRWKHVDPHIDPLO\*DGLGDHDVERWKKDGGRFNDQGSROORFN&RGLVDORZIDWćDN\ZKLWHPHDWĆVKWKDWLVDJRRG VRXUFH RI SURWHLQ SKRVSKRUXV QLDFLQ DQG YLWDPLQ % 7KH $WODQWLF FRG PDMRU DQWLJHQ *DG P  ZDV LGHQWLĆHG DV SDUYDOEXPLQ

Current Result Previous Result Reference Range

IgG 3.2 2.0 ≤2.0 0.1 2.0 4.0 6.0

IgA 0.7 1.9 ≤2.0 0.1 2.0 4.0 6.0

)ODWĆVK 3ODLFH6ROH)ORXQGHU

3ODLFHVROHDQGćRXQGHUDUHFRPPRQQDPHVIRUWKUHHGLIIHUHQWJURXSVRIćDWĆVK3ODLFHVHHPWRVKDUHPRGHUDWHDQWLJHQLF FRPSRQHQWV ZLWKLQ JURXSV RI ĆVK HJ FRGĆVK KDNH PDFNHUHO DQG WXQD  6SHFLĆF ,J( DQWLERGLHV WR SODLFH KDYH EHHQ PHDVXUHGLQDWRSLFGHUPDWLWLVSDWLHQWVDQGLQIRRGDOOHUJLFFKLOGUHQ

Current Result Previous Result Reference Range

IgG 1.8 1.2 ≤2.0 0.1 2.0 4.0 6.0

IgA 1.7 <0.1 ≤2.0 0.1 2.0 4.0 6.0

0RQNĆVK

0RQNĆVKDOVRNQRZQDVIURJĆVKLVDPHPEHURIWKH/RSKLXVJHQXVIRXQGLQWKH$WODQWLFDQG,QGLDQ2FHDQV0RQNĆVK SURYLGHVEHQHĆFLDOPLQHUDOVDVZHOODVSURWHLQVDQGYLWDPLQV+RZHYHU0RQNĆVKLVUHODWLYHO\KLJKLQPHUFXU\DQGLWFDQ SRVHKHDOWKULVNVLIHDWHQLQODUJHDPRXQWV

Current Result Previous Result Reference Range

IgG 0.7 1.4 ≤2.0 0.1 2.0 4.0 6.0

IgA 0.1 0.2 ≤2.0 0.1 2.0 4.0 6.0

Page 9 of 16 Vibrant Wellness | 1360 Bayport Ave, Ste B. San Carlos, CA 94070 SeafoodZoomer 1(866) 364-0963 | [email protected] | www. vibrant-wellness.com

LASTLAST NAME NAME FIRSTFIRST NAME NAME MIDDLEMIDDLE NAME NAME DATE OF BIRTHGENDER GENDERDATE OF PHYSICIANBIRTH ID ACCESSION ID

TESTNAME PATIENT MALE 1996-10-22 1512010000

)LVK2LO\RU)DWW\ĆVK

Mackerel and Tuna

0DFNHUHODQGWXQDDUHPHPEHUVRIWKHVDPHIDPLO\6FRPEULGDHZKLFKLQFOXGHVPDQ\VSHFLHVRIRSHQVHDĆVK0DFNHUHO KDVRXWHUOD\HUVRIUHGPHDWDQGOLJKWHULQWHULRUOD\HUVRIPHDW%RWKRIWKHPDUHDPRQJWKHWRSĆVKRQWKHOLVWIRURPHJD IDWW\DFLGFRQWHQWDQGYLWDPLQ%&DQQHGPDFNHUHOPD\KDYHUHGXFHGDQWLJHQLFLW\DVLVIRXQGZLWKWXQD

Current Result Previous Result Reference Range

IgG 1.3 1.5 ≤2.0 0.1 2.0 4.0 6.0

IgA 0.5 1.6 ≤2.0 0.1 2.0 4.0 6.0

Salmon and Trout

6DOPRQDQGWURXWDUHPHPEHUVRIWKHVDPHIDPLO\6DOPRQLGDOVRNQRZQDVUD\ĆQQHGĆVK$OOW\SHVRIVDOPRQDQGWURXW SURYLGHDJRRGVRXUFHRIKLJKTXDOLW\SURWHLQDQGWKHKHDUWKHDOWK\RPHJDIDWW\DFLGV7KHWU\SWRSKDQIRXQGLQVDOPRQ LVDSUHFXUVRUWRVHURWRQLQZKLFKPD\KHOSPDQDJHGHSUHVVLRQ6DOPRQLVDJRRGVRXUFHRIYLWDPLQ'DQGLQJHVWLQJLWPD\ DOVRKHOSWRLPSURYHPRRGSURWHFWDJDLQVWPDFXODUGHJHQHUDWLRQDQGDLGLQERQHKHDOWK6PRNHGVDOPRQLVOLNHO\WRKDYH DQWLJHQLFSURSHUWLHVVLPLODUWRRUGLQDU\ĆVK&DQQHGVDOPRQPD\KDYHUHGXFHGDQWLJHQLFLW\DVLVIRXQGZLWKWXQD

Current Result Previous Result Reference Range

IgG 5.4 1.3 ≤2.0 0.1 2.0 4.0 6.0

IgA 1.2 0.4 ≤2.0 0.1 2.0 4.0 6.0 Specific Reactivity: Sockeye salmon IgG, Pink salmon IgG

6DUGLQH+HUULQJ3LOFKDUG

6DUGLQHKHUULQJDQGSLOFKDUGDUHFRPPRQQDPHVXVHGWRUHIHUWRYDULRXVVPDOORLO\ĆVKLQWKHIDPLO\&OXSHLGDH7KH\DUH DQ H[FHOOHQW VRXUFH RI YLWDPLQ % VHOHQLXP SKRVSKRUXV RPHJD IDWW\ DFLGV SURWHLQ DQG YLWDPLQ ' 6DUGLQHV DUH FRPPRQO\FDQQHGDVWKH\DUHSHULVKDEOHKRZHYHUVHQVLWLYLW\WRWKHPDUHQRWUDUH7KHRYHUODSDQWLJHQLFLW\EHWZHHQWKLV JURXSDQG*DGLIRUPHV HJFRGĆVKKDNH DQG6FRPEURLGĆVKHV H[DPSOHVPDFNHUHODQGWXQD VHHPWREHPRGHUDWHRU HYHQVPDOO

Current Result Previous Result Reference Range

IgG 1.7 0.7 ≤2.0 0.1 2.0 4.0 6.0

IgA 0.4 1.7 ≤2.0 0.1 2.0 4.0 6.0

Page 10 of 16 Vibrant Wellness | 1360 Bayport Ave, Ste B. San Carlos, CA 94070 SeafoodZoomer 1(866) 364-0963 | [email protected] | www. vibrant-wellness.com

LASTLAST NAME NAME FIRSTFIRST NAME NAME MIDDLEMIDDLE NAME NAME DATE OF BIRTHGENDER GENDERDATE OF PHYSICIANBIRTH ID ACCESSION ID

TESTNAME PATIENT MALE 1996-10-22 1512010000

Anchovies

$QFKRY\LVDVPDOOFRPPRQIRUDJHĆVKRIWKHIDPLO\(QJUDXOLGDH7KHDQFKRY\EHLQJDQRLO\RUIDWW\ĆVKLVULFKLQRPHJD IDWW\DFLGVDQGSURWHLQZHOONQRZQIRULWVDELOLW\WRORZHUOHYHOVRIWULJO\FHULGHVDQGFKROHVWHUROLQWKHEORRG$QFKRY\ DQWLJHQVFDQEHHVSHFLDOO\SUREOHPDWLFEHFDXVHDQFKRYLHVDUHKLGGHQLQJUHGLHQWVLQRWKHUIRRGVVXFKDV:RUFHVWHUVKLUH VDXFH&DHVDUVDODGGUHVVLQJDQG%ORRG\0DU\FRFNWDLOV

Current Result Previous Result Reference Range

IgG 0.5 1.9 ≤2.0 0.1 2.0 4.0 6.0

IgA 1.1 1.0 ≤2.0 0.1 2.0 4.0 6.0

2WKHUĆVK

Bass

%DVVLVDPHPEHURIWKH6HUUDQLGDHIDPLO\%RWKVHDDQGIUHVKZDWHUEDVVLVORZLQFDORULHVDQGVHUYHVDVDQH[FHOOHQWVRXUFH RISURWHLQVHOHQLXPDQGHVVHQWLDORPHJDIDWW\DFLGVZKLOHKDYLQJYDU\LQJDPRXQWVRIYLWDPLQV%DQG%

Current Result Previous Result Reference Range

IgG 2.0 1.6 ≤2.0 0.1 2.0 4.0 6.0

IgA 1.4 0.6 ≤2.0 0.1 2.0 4.0 6.0

Carp

&DUSLVDPHPEHURIWKHIDPLO\&\SULQLGDHDYHU\ODUJHJURXSRIĆVKQDWLYHWR(XURSHDQG$VLD&DUSDVDQRLO\IUHVKZDWHU YDULHW\LVLQFUHGLEO\ULFKLQPLQHUDOVDQGYLWDPLQVDVZHOODVKLJKOHYHOVRIEHQHĆFLDOIDWW\DFLGVSURWHLQDQGDQWLR[LGDQWV

Current Result Previous Result Reference Range

IgG 1.0 1.9 ≤2.0 0.1 2.0 4.0 6.0

IgA 1.9 0.7 ≤2.0 0.1 2.0 4.0 6.0

Page 11 of 16 Vibrant Wellness | 1360 Bayport Ave, Ste B. San Carlos, CA 94070 SeafoodZoomer 1(866) 364-0963 | [email protected] | www. vibrant-wellness.com

LASTLAST NAME NAME FIRSTFIRST NAME NAME MIDDLEMIDDLE NAME NAME DATE OF BIRTHGENDER GENDERDATE OF PHYSICIANBIRTH ID ACCESSION ID

TESTNAME PATIENT MALE 1996-10-22 1512010000

&DWĆVK

&DWĆVKDUHDGLYHUVHJURXSRIUD\ĆQQHGĆVKQDPHGIRUWKHLUFDWèVZKLVNHUOLNHEDUEHOV&DWĆVKLVDPRGHUDWHO\IDWW\ĆVK WKDWLVDOVRDJRRGVRXUFHRIKLJKTXDOLW\SURWHLQDQG%YLWDPLQV$VDZKLWHĆVKFDWĆVKLVDPRQJWKHPRVWFRPPRQW\SHVRI ĆVKUHVXOWLQJLQDIRRGVHQVLWLYHUHDFWLRQ

Current Result Previous Result Reference Range

IgG 0.4 1.9 ≤2.0 0.1 2.0 4.0 6.0

IgA 0.5 1.4 ≤2.0 0.1 2.0 4.0 6.0

Other species

6RPHFRPPRQO\FRQVXPHGĆVKWKDWDUHQRWLQFOXGHGLQWKHDERYHIDPLOLHVDUHOLVWHG)RRGVHQVLWLYLWLHVKDYHDOVREHHQ IRXQGLQWKHVHĆVKVSHFLHV

Current Result Previous Result Reference Range

Bream IgG 0.1 2.0 ≤2.0 0.1 2.0 4.0 6.0

Bream IgA 1.4 1.1 ≤2.0 0.1 2.0 4.0 6.0

Current Result Previous Result Reference Range

Hake IgA 0.5 0.8 ≤2.0 0.1 2.0 4.0 6.0

Hake IgG 1.0 1.3 ≤2.0 0.1 2.0 4.0 6.0

Current Result Previous Result Reference Range Pufferfish IgG 0.4 1.7 ≤2.0 0.1 2.0 4.0 6.0 Pufferfish IgA 1.0 2.0 ≤2.0 0.1 2.0 4.0 6.0

Current Result Previous Result Reference Range

Croaker IgG 0.3 1.9 ≤2.0 0.1 2.0 4.0 6.0

Croaker IgA 2.0 1.2 ≤2.0 0.1 2.0 4.0 6.0

Current Result Previous Result Reference Range

Tilapia IgG 1.0 1.8 ≤2.0 0.1 2.0 4.0 6.0

Tilapia IgA 1.4 1.8 ≤2.0 0.1 2.0 4.0 6.0

Current Result Previous Result Reference Range Swordfish IgG 0.3 0.2 ≤2.0 0.1 2.0 4.0 6.0 Swordfish IgA 1.7 0.6 ≤2.0 0.1 2.0 4.0 6.0

Page 12 of 16 Vibrant Wellness | 1360 Bayport Ave, Ste B. San Carlos, CA 94070 SeafoodZoomer 1(866) 364-0963 | [email protected] | www. vibrant-wellness.com

LASTLAST NAME NAME FIRSTFIRST NAME NAME MIDDLEMIDDLE NAME NAME DATE OF BIRTHGENDER GENDERDATE OF PHYSICIANBIRTH ID ACCESSION ID

TESTNAME PATIENT MALE 1996-10-22 1512010000

3DUDVLWH

Anisakis simplex

$QLVDNLVVLPSOH[LVDSDUDVLWLFZRUPZKLFKLQIHFWVPDULQHĆVKRUVKHOOĆVK7KHSDUDVLWHFDQDOVRLQIHFWKXPDQV NQRZQDV DQLVDNLDVLV DVZHOODVWULJJHUVHQVLWLYHUHDFWLRQV6HQVLWLYHUHDFWLRQVWR$QLVDNLVVLPSOH[FDQEHPLVWDNHQIRUVHQVLWLYLW\WR ĆVKRUVKHOOĆVK(LJKW$QLVDNLVVLPSOH[DQWLJHQVKDYHEHHQGHVFULEHGDWWKHPROHFXODUOHYHO $QLVWR$QLV $QLVLVQRZ NQRZQWRRFFXULQGLIIHUHQWLVRIRUPVDQGKDVEHHQIRXQGWREHKLJKO\UHVLVWDQWWRKHDW$QLV SDUDP\RVLQ LVVLPLODUWR SDUDP\RVLQIURPGXVWPLWHVDQGWKHVLPLODULW\LQVHTXHQFHRIWKHVHKLJKO\FRQVHUYHGSURWHLQVLVSUREDEO\WKHFDXVHRI FURVVUHDFWLYLW\ELQGLQJWR$QLVDNLVVLPSOH[SURWHLQVVHHQIRU*HUPDQFRFNURDFKHVFKLURQRPLGVDQGGXVWPLWHV Current Result Previous Result Reference Range

IgG 2.1 0.9 ≤2.0 0.1 2.0 4.0 6.0

IgA 4.5 1.7 ≤2.0 0.1 2.0 4.0 6.0

Page 13 of 16 Vibrant Wellness | 1360 Bayport Ave, Ste B. San Carlos, CA 94070 SeafoodZoomer 1(866) 364-0963 | [email protected] | www. vibrant-wellness.com

Key Terms/Glossary

1ঞm $FWLQSURWHLQLVDQLPSRUWDQWFRQWULEXWRUWRWKHFRQWUDFWLOHSURSHUW\RIPXVFOHDQG RWKHUFHOOV

mঞ0o7‹ $Q DQWLERG\ DOVR NQRZQ DV DQ LPPXQRJOREXOLQ ,J  LV D ODUJH <VKDSHG SURWHLQ SURGXFHGPDLQO\E\SODVPDFHOOVWKDWLVXVHGE\WKHLPPXQHV\VWHPWRQHXWUDOL]H SDWKRJHQVVXFKDVSDWKRJHQLFEDFWHULDDQGYLUXVHV

uovvŊu;-1ঞˆb|‹ &URVVUHDFWLYLW\KDSSHQVZKHQDQDQWLERG\GLUHFWHGDJDLQVWRQHVSHFLĆFDQWLJHQ DOOHUJHQ LVVXFFHVVIXOLQELQGLQJZLWKDQRWKHUGLIIHUHQWDQWLJHQ

Crustacean &UXVWDFHDQVIRUPDODUJHGLYHUVHDUWKURSRGWD[RQZKLFKLQFOXGHVVXFKIDPLOLDU DQLPDOVDVFUDEVOREVWHUVFUD\ĆVKVKULPSNULOOZRRGOLFHDQGEDUQDFOHV

Decapod 7KH 'HFDSRGD RU GHFDSRGV DUH DQ RUGHU RI FUXVWDFHDQV ZLWKLQ WKH FODVV 0DODFRVWUDFD LQFOXGLQJ PDQ\ IDPLOLDU JURXSV VXFK DV FUD\ĆVK FUDEV OREVWHUV SUDZQVDQGVKULPS0RVWGHFDSRGVDUHVFDYHQJHUV

Histamine +LVWDPLQHLVDQRUJDQLFQLWURJHQRXVFRPSRXQGLQYROYHGLQORFDOLPPXQHUHVSRQVHV DV ZHOO DV UHJXODWLQJ SK\VLRORJLFDO IXQFWLRQ LQ WKH JXW DQG DFWLQJ DV D QHXURWUDQVPLWWHUIRUWKHEUDLQVSLQDOFRUGDQGXWHUXV+LVWDPLQHLVLQYROYHGLQWKH LQćDPPDWRU\UHVSRQVHDQGKDVDFHQWUDOUROHDVDPHGLDWRURILWFKLQJ

IgA ,PPXQRJOREXOLQ$ ,J$ DVDPDMRUFODVVRIDQWLERG\SUHVHQWLQWKHPXFRVDO VHFUHWLRQVRIPRVWPDPPDOVUHSUHVHQWVDNH\ĆUVWOLQHRIGHIHQVHDJDLQVWLQYDVLRQ E\LQKDOHGDQGLQJHVWHGSDWKRJHQVDWWKHYXOQHUDEOHPXFRVDOVXUIDFHV

IgG ,PPXQRJOREXOLQ* ,J* DVWKHPRVWDEXQGDQWW\SHRIDQWLERG\LVIRXQGLQDOOERG\ ćXLGVDQGSURWHFWVDJDLQVWEDFWHULDODQGYLUDOLQIHFWLRQV$Q,J*UHDFWLRQWRIRRG SURWHLQVVXJJHVWVWROHUDQFHUHODWHGWRLPPXQHFHOOUHDFWLRQ5HSHDWHGH[SRVXUH LQćDPPDWLRQ DQG LPPXQH UHDFWLYLW\ FRQWULEXWH WR VHQVLWLYLW\ DQG KLJK ,J* LQ UHVSRQVHWRIRRGSURWHLQV

Isoform $SURWHLQLVRIRUPLVRQHRIDQXPEHURIGLIIHUHQWVWUXFWXUDOO\VLPLODUSURWHLQVWKDW DUHFUHDWHGDVWKHUHVXOWRIDOWHUQDWLYHVSOLFLQJRUIURPVLPLODUJHQHVIRUPHGIURPD FRSLHGJHQHDQGGLIIHUHQWLDWHGDVWKHUHVXOWRIHYROXWLRQ

‹ovbm 0\RVLQVDUHDVXSHUIDPLO\RIPRWRUSURWHLQVEHVWNQRZQIRUWKHLUUROHVLQPXVFOH FRQWUDFWLRQDQGLQDZLGHUDQJHRIRWKHUPRWLOLW\SURFHVVHVLQHXNDU\RWHV

Page 14 of 16 Vibrant Wellness | 1360 Bayport Ave, Ste B. San Carlos, CA 94070 SeafoodZoomer 1(866) 364-0963 | [email protected] | www. vibrant-wellness.com

Citations/Sources

[1] 0RWR\DPD.6XPD<,VKL]DNL61DJDVKLPD< 6KLRPL.  0ROHFXODUFORQLQJRIWURSRP\RVLQV LGHQWLĆHG DV DOOHUJHQV LQ VL[ VSHFLHV RI FUXVWDFHDQV -RXUQDO RI DJULFXOWXUDO DQG IRRG FKHPLVWU\    å [2]

Page 15 of 16 Vibrant Wellness | 1360 Bayport Ave, Ste B. San Carlos, CA 94070 SeafoodZoomer 1(866) 364-0963 | [email protected] | www. vibrant-wellness.com

Risk and Limitations

$_bv|;v|_-v0;;m7;ˆ;Ѵor;7-m7b|vr;u=oul-m1; 1_-u-1|;ubv|b1v 7;|;ulbm;70‹(b0u-m|l;ub1- ĺķ-1;u|b=b;7Ѵ-0ĺ$_;v;-vv-‹v_-ˆ;mo|0;;m1Ѵ;-u;7ou-rruoˆ;70‹|_;&ĺ"ĺ oo7-m7 u†]7lbmbv|u-|bomĺ

ѴѴ;u];mŊvr;1b=b1] -vv-‹v7omo|7;lomv|u-|;-0voѴ†|;rovb|bˆ;-m7m;]-|bˆ;ru;7b1|bˆ;ˆ-Ѵ†;v=ou -ѴѴ;u]b1 7bv;-v;ĺ Ѵbmb1-Ѵ _bv|ou‹ l†v| 0; bm1ourou-|;7 bm|o |_; 7b-]mov|b1 7;|;ulbm-|bomĺ †-m|b=b1-|bom o= vr;1b=b1 ] -m7 ] -m|b0o7b;v bv mo| Ŋu;1o]mbŒ;7 7b-]mov|b1 bm7b1-|ou o= -ѴѴ;u]‹ĺ

";-=oo7 ,ool;u |;v|bm] bv r;u=oul;7 -| (b0u-m| l;ub1-ķ - 1;u|b=b;7 Ѵ-0ou-|ou‹ -m7 †|bѴbŒ;v "ŊƐƒƓѶƔ 7;ˆ;Ѵor;7 |;1_moѴo]‹ĺ (b0u-m| l;ub1- _-v ;==;1|bˆ; ruo1;7†u;v bm rѴ-1; |o ruo|;1| -]-bmv| |;1_mb1-Ѵ -m7 or;u-|bom-Ѵ ruo0Ѵ;lvĺ o‰;ˆ;uķ v†1_ ruo0Ѵ;lv l-‹ v|bѴѴ o11†uĺ Š-lrѴ;v bm1Ѵ†7; =-bѴ†u; |o o0|-bm |_; u;v†Ѵ| =ou - vr;1b=b1 -m|b];m 7†; |o 1bu1†lv|-m1;v 0;‹om7 (b0u-m|Ľv 1om|uoѴĺ(b0u-m|l-‹u;Ŋ|;v|-v-lrѴ;bmou7;u|oo0|-bm|_;v;u;v†Ѵ|v0†|†romu;Ŋ|;v|bm]|_;u;v†Ѵ|v l-‹ v|bѴѴ mo| 0; o0|-bm;7ĺ v ‰b|_ -ѴѴ l;7b1-Ѵ Ѵ-0ou-|ou‹ |;v|bm]ķ |_;u; bv - vl-ѴѴ 1_-m1; |_-| |_; Ѵ-0ou-|ou‹1o†Ѵ7u;rou|bm1ouu;1|u;v†Ѵ|vĺ|;v|;7bm7bˆb7†-Ѵl-‹‰bv_|or†uv†;=†u|_;u|;v|bm]|o ˆ;ub=‹-m‹u;v†Ѵ|vĺ

$_;bm=oul-|bombm|_bvu;rou|bvbm|;m7;7=ou;7†1-|bom-Ѵr†urov;vomѴ‹ĺ)_bѴ;;ˆ;u‹-||;lr|_-v 0;;ml-7;|oruoˆb7;1†uu;m|-m7-11†u-|;bm=oul-|bomķm;b|_;u|_;-†|_oumou|_;r†0Ѵbv_;u1-m0; _;Ѵ7-11o†m|-0Ѵ;=ou-m‹;uuouvouolbvvbomvĺ

(b0u-m| );ѴѴm;vv l-h;v mo 1Ѵ-blv -v |o |_; 7b-]mov|b1 ou |_;u-r;†|b1 †v; o= b|v |;v|v ou o|_;u bm=oul-|bom-Ѵl-|;ub-Ѵvĺ(b0u-m|);ѴѴm;vvu;rou|v-m7o|_;ubm=oul-|bom7omo|1omv|b|†|;l;7b1-Ѵ -7ˆb1; -m7 -u; mo| - v†0v|b|†|; =ou ruo=;vvbom-Ѵ l;7b1-Ѵ -7ˆb1;ĺ Ѵ;-v; 1omv†Ѵ| ‹o†u _;-Ѵ|_1-u; ru-1|b|bom;u=out†;v|bomvu;]-u7bm]|;v|u;v†Ѵ|vķou0;=ou;0;]bmmbm]-m‹1o†uv;o=v†rrѴ;l;m|-|bom ou7b;|-u‹1_-m];vĺ

Page 16 of 16