WHO Americas Region (PAHO) Source: Globocan 2018

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WHO Americas region (PAHO) Source: Globocan 2018

Number of new cases in 2018, both sexes, all ages Geography

Breast 462 081 (12.2%)

Prostate 424 663 (11.2%)

Lung Other cancers 342 518 (9%) 2 129 190 (56.2%) Colorectum 307 777 (8.1%)

Thyroid 125 288 (3.3%)

Total: 3 791 517

Number of new cases in 2018, males, all ages Numbers at a glance

Total population Prostate 424 663 (21.7%) 1015856487 Lung 185 707 (9.5%) Number of new cases Other cancers Colorectum 1 032 073 (52.7%) 156 934 (8%)

Bladder 90 730 (4.6%) 3791517

Number of deaths Non-Hodgkin lymphoma 66 692 (3.4%) Total: 1 956 799 1371024 Number of new cases in 2018, females, all ages Number of prevalent cases (5-year)

Breast 462 081 (25.2%) 11468905

Lung 156 811 (8.5%) Data source and methods Other cancers 871 940 (47.5%) Colorectum 150 843 (8.2%) Incidence

Thyroid Population weighted average of the rates of the region- 98 482 (5.4%) specific countries included in GLOBOCAN 2018.

Mortality Corpus uteri 94 561 (5.2%) Population weighted average of the rates of the region- specific countries included in GLOBOCAN 2018. Total: 1 834 718 Prevalence Summary statistic 2018 Sum of region-specific prevalent cases.

Males Females Both sexes Populations included Population 502 386 679 513 469 796 1 015 856 487

Number of new cancer cases 1 956 799 1 834 718 3 791 517 Caribbean, Central America, North America, South America Age-standardized incidence rate (World) 291.4 246.6 265.2 Risk of developing cancer before the age of 75 years (%) 28.7 24.0 26.2 Number of cancer deaths 713 463 657 561 1 371 024 Age-standardized mortality rate (World) 101.9 80.2 89.6 Risk of dying from cancer before the age of 75 years (%) 10.4 8.4 9.4 5-year prevalent cases 5 663 206 5 805 699 11 468 905 Top 5 most frequent cancers excluding non-melanoma skin cancer Prostate Breast Breast (ranked by cases) Lung Lung Prostate Colorectum Colorectum Lung Bladder Thyroid Colorectum Non-Hodgkin Corpus uteri Thyroid lymphoma

Incidence, Mortality and Prevalence by cancer site

New cases Deaths 5-year prevalence (all ages) Cancer Number Rank (%) Cum.risk Number Rank (%) Cum.risk Number Prop. Breast 462 081 1 12.2 7.35 99 521 2 7.3 1.41 1 727 435 0 Prostate 424 663 2 11.2 8.19 86 484 4 6.3 0.87 1 251 023 0 Lung 342 518 3 9.0 2.82 254 662 1 18.6 1.95 369 441 0 Colon 197 356 4 5.2 1.49 97 246 3 7.1 0.64 530 443 0 Thyroid 125 288 5 3.3 1.04 6 426 24 0.47 0.05 479 023 0 Bladder 120 787 6 3.2 0.90 31 999 13 2.3 0.17 389 117 0 Non-Hodgkin lymphoma 120 771 7 3.2 0.96 41 294 10 3.0 0.27 356 035 0 Kidney 99 362 8 2.6 0.86 31 546 14 2.3 0.24 268 558 0 Melanoma of skin 97 856 9 2.6 0.78 16 020 20 1.2 0.11 334 194 0 Stomach 96 333 10 2.5 0.74 65 317 7 4.8 0.47 135 905 0 Rectum 96 144 11 2.5 0.80 29 032 16 2.1 0.21 276 854 0 Corpus uteri 94 561 12 2.5 1.68 19 391 18 1.4 0.30 349 007 0 Leukaemia 93 680 13 2.5 0.70 53 163 8 3.9 0.34 270 526 0 Pancreas 91 272 14 2.4 0.70 84 056 5 6.1 0.62 57 572 0 Liver 80 251 15 2.1 0.67 70 775 6 5.2 0.56 61 902 0 Cervix uteri 71 689 16 1.9 1.12 34 170 12 2.5 0.52 212 862 0 Brain, central nervous system 56 601 17 1.5 0.45 42 285 9 3.1 0.35 158 315 0 Ovary 50 479 18 1.3 0.80 29 530 15 2.2 0.44 141 370 0 Lip, oral cavity 47 010 19 1.2 0.40 13 072 22 0.95 0.10 144 440 0 Multiple myeloma 43 694 20 1.2 0.36 25 277 17 1.8 0.18 110 083 0 Oesophagus 43 664 21 1.2 0.36 36 116 11 2.6 0.29 44 751 0 Larynx 33 396 22 0.88 0.30 14 656 21 1.1 0.12 104 343 0 Gallbladder 33 082 23 0.87 0.25 18 478 19 1.3 0.13 35 506 0 Testis 24 798 24 0.65 0.35 2 448 30 0.18 0.03 97 301 0 Oropharynx 22 500 25 0.59 0.20 8 549 23 0.62 0.07 74 174 0 Hodgkin lymphoma 20 863 26 0.55 0.16 3 778 26 0.28 0.03 79 883 0 Anus 14 277 27 0.38 0.12 2 509 29 0.18 0.02 41 757 0 Salivary glands 10 595 28 0.28 0.08 2 722 28 0.20 0.02 27 204 0 Vulva 10 116 29 0.27 0.14 2 807 27 0.20 0.03 32 958 0 Penis 6 740 30 0.18 0.10 1 836 33 0.13 0.03 20 412 0 Mesothelioma 6 038 31 0.16 0.04 3 964 25 0.29 0.03 6 247 0 Hypopharynx 5 881 32 0.16 0.05 1 865 32 0.14 0.02 9 972 0 Nasopharynx 5 092 33 0.13 0.04 2 360 31 0.17 0.02 16 118 0 Kaposi sarcoma 4 109 34 0.11 0.03 700 35 0.05 0.00 12 024 0 Vagina 3 564 35 0.09 0.05 1 093 34 0.08 0.01 10 221 0 All cancer sites 3 791 517 - - 26.17 1 371 024 - - 9.35 11 468 905 0

Age-standardized (World) incidence rates per sex, top 10 cancers

Males Females

Breast 66.5

Prostate 64.1 Lung 27.0 19.4 Colorectum 23.5 18.9 Thyroid 4.5 16.1 Non-Hodgkin lymphoma 10.4 7.2 Bladder 12.8 3.5 Leukaemia 8.9 6.1 Kidney 9.7 5.2 Melanoma of skin 8.3 5.9

80 60 40 20 0 20 40 60 80 ASR (World) per 100 000

Age-standardized (World) incidence and mortality rates, top 10 cancers

Incidence Mortality

Breast 66.5 12.9

Prostate 64.1 10.8 Lung 22.8 16.4 Colorectum 21.1 8.2 Corpus uteri 13.5 2.4 Cervix uteri 11.2 4.9 Thyroid 10.4 0.41 Non-Hodgkin lymphoma 8.7 2.7 Bladder 7.7 1.8 Leukaemia 7.4 3.7

80 60 40 20 0 20 40 60 80 ASR (World) per 100 000