The Newsletter of the NIH Alumni Association
Summer 1995 Vol. 7, No. 2 date Breakfast with Raskey From 'Watermelon to Plum' NIH's 'Iron Man' Marks NIH Edges Closer to 65th Year of Service 20·Year Master Plan
By Carla Gameu By Rich McMa1111s
Sitting around a Bldg. I cafeteria Toward the end of NIH"s recent cable at about 7:30 on a recent Friday employee meeting on drafting a new morning, Roskey Jennings, who'd just 20-year master plan for the Bethesda finished a week of night shifts, remem campus, Sieve Ficca. NIH associate bered something humorous that former director for research services, coined a NIH director Dr. James Shannon once metaphor that may well have explained said to him: ··He said. "Roscoe. you go the modest turnout for the event. The out side and hang over the side of the master plan. he said. could be thought front ra il. And you just stay there. of as a watermelon that. once pared And if anyone says anything to you Dr. Maxine F. Singer away by budget realities. shifts in sci about it. you te ll them this building is ence, and vagaries of staffing and plan just as much yours as it is mine. Your Singer Chosen as 1995 ning needs over the next two decades. name ought to go right along side could shrink to the size of a plum: mine. Public Service Awardee NIH"ers. it seems. are really more inter Since Bldg. I was renamed in honor ested in plums than watennelons. The NlH Alumni Association is of Shannon in 1983. that quote has Lo But it was a pretty succulent water pleased to announce that its third Public be at least 12 years old. It 's probably melon that was on view May 16 in Service Award will go to Dr. Maxine F. not even remarkable to recall the story. Lipsetr Amphitheater as planning con Singer. except that Jennings can remember NIH sultants and IH authorities unveiled Singer. president of the Carnegie tales loLS further back than that. He can details-collected s ince the last draft Institution of Washington since 1988. remember when he used to chat fre was introduced in 1993-of the Big graduated from Swarthmore College in quently with Shannon- when Shannon Picture for year 20 15. 1952, receiving an A.B. with high hon was director during NIH" s golden days ors. She proceeded to Yale University (See Master Plan p. 18) (See Jennings p. 20) for graduate study, where she was awarded a Ph.D. in biochemistry in In This Issue Page 1957. Joining the ational In stitutes of NIHAA members bridetl 011 budget, Health initially as a postdoctoral fel ··reim·emi Singer ( comi1111ed.fi·o111 p. I ) Carnegi.e rnstirution's aclministrntion Her contribuLions ro the public good building. have not been limited, however. to her She has been the recipient or numer Update research. From her early days as a sci ous major honors, including the entisr, she took a leadership role in Distinguished Presidemial Rank A ward The NIHAA Uptf(lfe is the newslefler of the speaking ouL on policy. social and ( 1988); rhe National Medal of Science NIH Alumni Associmion. The NIHAA office moral issues. In 1957, she interpreted ( 1992): elect ion to Lhe National is 01 9101 Old George1m1·11 Rd .. Bethesda. MD 20814. (301) 530-0567. in the pages ofScience the research of Academy of Sciences ( 1979) and the Dr. Arthur Kornberg and his colleagues PontiJical Academy of Sciences ( 1986). Editor's Note involving the synthesis of DNA in She has served as a trustee of the Yale The NIHAA Updare welcomes leuers and l'irro. Ln 1973. she served as co-chair University Corporation. chairman of a news from re(lt/ers. We ll'ish 1101 011/y 10 of the Gordon Conference where early the Smithsonian Council, a director of brillf! alumni ne 11·s al10111 NIH . /mt also 10 concerns abour risks in recombinant the Whitehead Institute and of Johnson serve tis a means /(>r reporting i11formmio11 aho111 al1111111i-1heir co11cem .1'. information DNA research were ra ised. She was an Johnson and on the Board of & 011 recem appoi11tnu:111s. honors. books pub organizer of the landmark Asilomar Governors and Scientific Advisory lished and other developme11ts ofi111eresr to Conference and one of five signers of Council of the Weizmann Institute. their mllet1g11es. If you ht11•e nell's a/Jo111 Lhe summary st·mement of Lhe Asilomar yourself or ti/Joi// other alumni. or co111 She has also received numerous hon 1111:111s 011 and suggestions for the NINA.A Report. orary degrees. Updme. please drop a 1101e 10 rite editor. We More recently. reflecring her con On Thursday, Oct. 12, 1995, a recep reserl'e the right IO edit materials. cerns about the country ·s low level of tion in her honor will be hosted by the Ediror: Harriet R. Greenwald science educarion and publ'ic under N fl-I A lumni Asssociation at the Mary standing, she initiated the project. Woodard L asker Cemer (the C loister) N I HAA Ne ll'sletter Editorial A d .,isory "First Light" In this effort, from 5:30 p.m. to 7:30 p.m. fnvitations Commirtee Washington 3rd, 4th and 5th graders with detai ls will be mailed to members .Jerome G. Green. Clmimu111 anend a Saturday science school al the in September. Li11dt1 .I . 8roll'11 Mic'111£•I M. Gouesman Harrier R. Greemrald \licto,.ia A. Ht.mien Colleen IIenriclm!ll Leon Jacobs Harrn Klein Ro/Jeri G. Martin Almer Louis Nmkins Lois A. Sa/;11u111 Philip £. Schambra £/i;a/1er/1 H. Singer S10r111 Wlwlel' Rirlwrd G. \,ifyall NlflA A Newsletter 81)ard of Co11tributing Editors Giorgio Bernardi H. Franklin 8111111 Roger O. Egeberg Henryk £ise11bt•rg Donald S. Fredrickson Lars A. Hanson Wa/w· W. Holland Georoe Klein R ich~~·d M. Krause In a photo, circa 1956, members of the Laboratory of Biochemistry and Metabolism, Robert Q. Marston NIAMO, get together for a musical evening. They are (from I): Maxine Singer, alto recorder; Carlos Monge Bru ce Ames, alto recorder; Vi c Ginsburg, tenor recorder; and Jesse Rabinowitz, soprano Roger Monier Seymour Pt•n-;· re corder. Michael Sela 2 SUMMER 1 9 9 5 Members Briefed on NIH Budget, "Reinvention" NIHAA Bo(lr 3 N I H A A UPDATE ;\ w w al Meeting ( conti1111edji·o111 p. 3) & D contract proposals. Beginning phone directory is now provided On medical research in any healtJ1 care with the February 1995 reviews. all line as well as to the CRISP database reform package. The fund so created Division of Research Grants srudy sec which lists all NIH grants and con for medical research would supplement tions have employed a streamlined tracts. the budget of rhe NrH through a I per review process that allows for fuller The third speaker at the meeting was cent set-aside of health-insurance pre discussion of applications identified in Dr. Roben N. Burler. founding director miums and a voluntary check-off on advance by reviewers as the best of the National Institute on Aging who income tax returns. (approximately half of pending applica now heads the Institute on Aging In response to the question "Do we tions.) Only the upper "half ' of appli Research at Mt. Sinai School of do harm in strong advocacy of research cations wi ll receive scores. This proce Medicine, N.Y. He chal lenged the over olher national needs?" she dural change followed successful pilot NIHAA LO take a strong role in public responded that "to be quiet would studies conducted on two review education. He warned that the health invite the cyclone. Members of rounds in 1994. Under another change. prospects for our rapidly aging popula Congress respond to the people they now in effect. all applicants will tion are in jeopardy. citing the drive 10 represent, especially when they give receive the essentiall y unedited com cut Medicare. threats to the suppon of good reasons for what they request. .. ments and critiques from reviewers. fundamental and clinical research on Morella said, adding, "and you have Scored applications will be given a aging and gaps in the trnining of physi good reason.'' "Resume and Summary of Discussion'· cians. He The audience was also given a view in addition to the critiques. was gloomy of "reinventi on," from an opera1ional Experimental procedures are under regarding perspective way to postpone l'he collection of a fair prospects for by Dr. ly substantial amount of the "other sup NIH in gen Wendy port'' information and complete budget eral and Baldwin. detail currently required at the rime of emphasized NIH deputy submission of all grant applications. the need for director for This would reduce the administrative better public extramural burden associated with grant applica understand research. tion without compromising the initial ing of the The NIH review for scientific merit. Detailed practical extramural budget informat ion relevant to an value of research. Butler said he feels programs award would be submiued when it is that the NIH Alumn i Association can have been first needed, "just in time" prior to do much in public education. that we designated one of the several Executive award. This would reduce the adminis should lake the lead in helping to lind Branch "reinvention laboratories" to trative burden for the approximately 75 additional sources of financial support lead in the process of change for extra percent of applicants who do not for research. "As alumni ... he said. "we mural functions in the Publ ic Health receive an award. can be outspoken and maybe outra Service. She told how this particular Pilot experiments arc under way as a geous" (Sec excerpts from his talk " laboratory" activity. which she heads, part of the planning process for effec starting on page 5.) has facilitated efforts of the Office of ti ve use of electronic communications Ex tramural Research to reevaluate NIH technologies for the exchange of essen At the business meeting part of the policies and procedures. In her view tial information in the application and program, Dr. Wi ll iam S. Jordan. nomi "reinvention" came along at a good grant administration processes. Since nating committee chairman, reported time to give impetus to ongoing efforts there is diversity in the way applicant the election by the board of directors of to improve the way Nl H does business. organizations use systems 10 create the following officers for two-year Baldwin spoke of her long-standing app lications. NIH is cooperating with terms: interest in reducing .. administrivia." other federal agencies to design and President: Calvin B. Baldwin. Jr. Initia ti ves are underway to stream publish Electronic Data Interchange Vice President: Dr. William I. Gay line peer review and processing of standards. Vice President : Dr. Joseph Perpich research grant applications as well us R Access to the NIH Guide and tele Secretary: Storn1 Whaley 4 SUMMER 1 9 9 5 Treasurer: Dr. Harley Sheffield. Health Prospects for An Aging Population Noting that. under the NIH AA Constitut ion. two-thirds of the vacan By Dr. Robert N. B11tler aging! ... cies in Lhe board of directors are fi lled Research in aging is not only in jeop by vote of the board, and one third by a (Editor's note: This is rite excerpted re.rt ardy, NIH as a whole is. As you well membership ballot. Jordan an nounced ofa /(//k de/frered by Dr. Robert N. 8111/er know despite the passage of the the following were elected by the board a1 rite annual meeting oflite NIHAA on .!1111e Hatfield Amendment- thankfully to se rve a three-year term: 10. 1995. lfyo11 wo11/d like a copy ofrite and its possible influence upon the Dr. Peter Conclliffe entire re.rl plet1se write 10 1/te NIHAA. 9101 forthcoming conference between the Dr. Marguerite Coomes Old George1own Rd .. Be1'1esda. MD 20814). House and the Senate, we are likely to Dr. William Goldwater see a real decline of NIH support below Ms. Jane Leitch ... The ultimate prospect for better inllation. We will likely see a decline health for an aging population resides Dr. Pau I Parkman in training monies as well as fewer Dr. Eugene Weinbach. in fundamental and clinical research. It is for that reason that I took special grants. pride when l had the opportunity and It is not possible to make up these The fol lowing were elected by ballot responsibility to direct the National losses in the corporate, foundation and of the NIH AA membership: Institute on Aging in trying to build up philanthropic world- although we Mr. Joseph Keyes a field which was then considered both must try. Dr. Bayard Morrison modest and diffuse. Modest in its Today, we confront a kind of Dr. Joseph Perpich (also elected vice development and diffuse and capacious American mindless ·'Cultural president) in its content and goals. Revolution" with marked anti-intellec Dr. Marvin Schneiderman. The National lnstitute on Aging's tualism. rising anti-science. anti-schol status has improved. The field of arship, anti-humanities. anti-arts. anti Following the forma l presentations research in aging is no longer consid public broadcasting. and a business meeting, 1he members ered second rate. The NIA has made Those of us who are in the scholarly and guests adjourned 10 a barbecue significant contributions to understand and service professions must not "picnic" arranged by board member ing Alzheimer's disease such as the become divided, for example, science Randy Schools in the Rathskeller finding that Apolipoprotein E4 is a ri sk against service, and service against sci Room of the Mary Woodard Lasker factor. The institute has prospered rea ence. Moreover, the l'ield of science Center. sonably well in part because of its dedi itself must not be divided, for example. cation to Alzheimer's disease. with allacks upon the intramural pro However, the institute's extramural gram by 1hc extramural communi ty. by grant support is not in balance. As basic scientists versus clinical investi much as 50 percent of its support goes The NIHAA gators, etc. to one disease alone, Alzheimer's dis Whal can we do to support science at Historical Committee ease, despite 1he myriad diseases and NIH in general and aging research in Needs Your Help disabilities of age. Moreover the NIA particul ar that would help build health should be able to provide greater sup prospects for an aging America? We The NIH AA historical commit port for studies of the basic biology of must be more willing as scientists and tee has contracted with NIH to aging in addition to elucidation of its scholars to help educate the American conduct a comprehensive survey social and behavioral aspects. Do not community about science. This will of historical memorabilia and misunderstand, l favor every dollar that take time and energy. Obviously we objects. If you would like to vol goes to Alzheimer's disease research. cannot assume that money will simply unteer to help with this project There should be more! But. I am talk be given to us. We must translate our please contact Richard L. Scggel, ing about proportionate representation technical knowledge into clear under chairman of the cornmi11ce, at of target topics in a needed agenda for standable terms for the public. The (30 I) 424-6449. research in aging. NIH Alumni Association could help ... But we only spend $50 million a accomplish 1his. We must not be year to understand the basic biology of (See Butler p. 6) 5 N I H A A UPDATE Butler ( co11ti1111ed fi'om p. 5) tion must be drawn to those activities must be w illing to take chances-for arrogant about patronage. Understand thm are cl iflicult or impossible 10 do in science tends to become more conserv thal just as Joseph Haydn had an the academic world. T his is not a new ative when money is tight. Estcrhazy family. we need our pa11u11:-.. iclca at N IH. Studies that require the As an advocate of the modern new 100. We should actively seek individ longitudinal perspective arc illustrative. biology, molecular genetics and molec ual philanthropic support. Science A IDS research may be one example. ular biology in general. I agree enthusi should not and cannot depend upon We need to srudy the immune and other astically that the building blocks of life government alone. Before the re biological runc1ions of those who arc must be understood. A t the same time, invention Of government sweeps LIS H IV positive for years before sero-con we must not lose sight or the building away we should take leadersh ip in vcrsion. Longitudinality is certainly as well as the milieu or field in which helping to dcline what we think NIH quintessential to gerontologica l 1he building resides. shou ld be. I challenge the NIH Alumni research. which requires many mea We need the nexus of the basic biolo Association. As alumni we can afford surements over time. We must belier gist working with the clinic where to be outspoken. perhaps even outra understand the natural history of the searching questions arise. The Clinica l geous. We have lhc freedom to speak . menopause. Second, the NIH needs 10 Center was set up that way and in 1955 We should be s1rong lH advocates. focus more on chronic, multi-system when I first arrived. it was a statc-of How could NIH change its extramur diseases. Third, diversity, 10 be certain 1he-art building. We need a similar al programs? It cou ld be more proac that varied populations- by age. gen state-of-the-art (new) Clinical Center tive: N IH could carerully review its der and ethnicity-are represented in once again! extramural holdings and fill in the gaps. studies al N IH. Fourt h, interdiscipli We must not only reap 1he findings scicmific opportunities and needs. Not nary research. often difficult 10 accom in molecular biology but lest their gen just institute-by-institute but across plish in academia where one's promo eral applicability through clinical inves institutes. Trans-NIH efforts such as tions are dependent upon one's status 1igations and trials as well as establish aging arc illustrative. NIH could devel within one's own disciplinary specialty. 1heir appropriateness to specific condi op a new training system. a "coupling The NIMH Human Aging Study. 1955 1ions, often called outcomes research. sys tem." 10 ensure that those who win 66, catalyzed by 1he Kety-Schmidt We cer1 ainly need the new Clinical training grnn1s will also receive s1<1rt-up method or measuring blood flow. oxy Center and a range of clinical programs support grants ba.-;ed on systematic gen and glucose consumption is an in the country linanced possibly by new annua l re-evaluation. Clearly it is example of a successful N IH interdisci mechanisms and funding (perh aps socially unwise and personally disas plinary program. Fifth. NIH should under the DRG methodology.) trous 10 train people if there arc no deal w ith orphan or rare diseases. It is not my view that N IH should lit oppor1uni 1ics for them 10 pursue Sixth . further collaboration wi1h indus erally take on all these responsibilities research ca reers. Young people need try including animal model s. especially at once and work in all areas. but NIH something like a 5 year start-up to build aging animal models whose husbandry and its leadership must have a vision of compel it i vc careers. N fH could devel is very expensive. Consider the McCay the en tire spectrum of basic rescmch to op stronger partnerships wi1h the foun effect studies a1 Poolesville, application 10 care in its direction of dation and individual philanlhropic Maryland- testing of the effects of both the extra- and intramural pro organizations. NIH should work 10 low-caloric diets on life expectancy in grams. secure add itional funding via the non-human primates. Phamiaceutical To return to the issue of chronic dis Health Care Financing Administration companies are necessarily devoted to cases~th ey should certainly be studied (HCFA ). An example: One percent of application and depend upon NIH. An at NIH to a grea1er exten t given 1he rev health costs under Medicare should be estimated $ 100 billion of N IH funding olution in longevity. In 1975 the invested in research in aging and agc helped build the biotechnology indus admission of those over 65 to the rclmecl diseases. A wise invcs1men1 try. Seventh, N IH must maintain Clinical Center was less than 2 percent. since successful research is the ultimate breadth- from basic science 10 clinical This was defended. by saying that ii is cost containment. application and ex pand specialized difficult 10 study older people because Within 1hc intramural program a11 cn !ra ining opportuni1ies. Eighth. NIH of their frai lty and many confounding 6 SUMMER 1 9 9 5 variables. But that is precisely why gained nearly 28 years of life expectan fully realized but is of added impor older and fntil persons must be studied cy from birth in this country since tance given the rise of the devastating to understand belier multi-system dis 1900. And more than 5 years from dementias wi th aging. eases. their impact upon homeostasis base year 65. The revolution in It has been said that NrH is a victim and the different nature of the presenta longevity w ill become even more of its own successes by building extra tion and course or diseases in old age. intense in the next century. 1 IH should mural competitors. It i good that IH Ultimately, we must have a vision of be in the lead with st udies of the funda did so. So now we have to find new what we think arc the proper functions menial processes ofaging as well as the opporrunities to make new successes. of the Nationa l Institutes of Health at many associated cli scases. The clisease NIH is a great national treasure that this time. l. 1 is called 1he National mission institutes lwve already con must not be put at risk. We must all Institutes of Health. not of diseases. Its tributed enormously to building up respond to Tom Kennedy 's ..A Call to job is to address the health of the population aging. 1ow we need coor Anns.. Spring 1995 issue of the American people with respect to pre dination amongst the IH institutes to llHAA Updme. vention as well as care and treatment. address this new public health chal The Congressional commitment to This requires a spectrum of types of lenge, specifically the interact ing of reducing the federal deficit, downsizing research, which ultimately shou ld result aging and dise ases. To do so we must the fed era l government and emphasiz in more effective services. But never at be proactive, not passive. There should ing the power or the private market the expense of inadequate investmen t be an NIH-wide aging initiative as I place is vastly changing our country at in undifferentiuted. curiosity-driven already emphasized. large. including its science. Since sci ha~ic science ... Emerging populations like emerging ence and technology are the engines of The great 2 1st century issue will be diseases require special attention as we economic growth and.change. our aging. (Unless we lose th e battle move into the 2 1st cemury. The nation had best be careful that we do against infectious diseases.) We have Decade of th e Brain has never been nor stifle them. Since the health indus try is one-seventh of the nation's econ omy. its biggest industry and largest employer. we best beware of the law of unintended consequences when we introduce radical clumges of constraint. We need a national effort. perhaps a commission on the role of biomedical science in America-an engine to the economy as well as the basis of a healthy America. The IH Alumni Association should have a political arm and lobby on Capitol Hill. You also have the historic memory or value to contribute wise counsel to N IH planning. I challenge all of us who love this great institution to do all we can to pre serve that which is great and develop new directions where appropriate to build a new 2 1st century NIH. This is essen tial to ensure the health prospec ts of an aging population. indeed. to the Among the attendeesat the NIHAA annual meeting on June 10, 1995, are (fromI) Toby nation's population as a whole. Hertz, Dr. Robert N. Butler, Dr. Thomas Malone, co-chair of the annual meeting co mmittee, Thank you. Good health. and Dr. Roy Hertz. 7 N I H A A U P D A T E Research Festival '95 Schedule Announced NIH Research Festival '95 General Schedule of Events Mark your calendars for the 1995 All acti vities will take place in the William H. Natcher Bldg. (near the NlH Research Festival. scheduled for Metro station). unless otherwise noted. the week or Sept. 18-22. Dr. James Battey. scienti fic director for 1IDCD. SATUROA Y. SEPT. 16 chairs th is year·s organizing commi11ee. The annual festi val features NII-l's 10:00 a.m.-3:00 p.m. Public Open House intramural research programs. All are invited to attend. Nrl-IAA will have a table. Organizers plan to include 2 days of scientific meetings on Sept. 18 and 19. ~10~D \\ . SEPT. 18 with 2 major symposia. 24 workshops, and 4 poster sessions. All these events 8:30 a.m.- 11 :00 a.m. Symposium - Neuroscience, An NIH Sample are to be held in the Natcher Bldg. ·s Chair: Dr. Robert Wurtz. NEI conference faciliti es. I 1: 00 a.m.-1 :00 p.m. Poster Session I The week concludes with a Scientific 1: 30 p.m.-4:30 p.m. Workshop Session I Equipment Show, sponsored by the 4:30 p.m.-6:30 p.m. Poster Session 2 Technical Sales Association. Displays 6:30 p.m. Evening Picnic* and information booths are held in the Research Festival tents located in park * All a11enclees arc welcome; sponsored by the Technical Sales Association ing 10 1 lOD. (TSA). Tickets, ava ilable for a nominal fee, must be purchased in ad vance "The festival has al ways been a pop on the campus. ular format for NIH researchers to develop new contacts and establish net TUESDAY, SEPT. 19 works.'' said Tom Flavin. chairman of the commi11ee that coordinates the fes 8:30 a.rn.- 11 :00 a.111 . Symposium - Regulation of Cellular Functions by tival each year. ·· 11 · s a great chance to Protein Phosphorylation and Dephosphor~• l ation connect real people and faces with the Chair: Dr. Jacal yn Pierce, NCI names you read in research papers:· 11: 00 a.111.- I :00 p.111. Poster Session 3 The Research Festi val was begun 10 I :30 p.m.-4:30 p.m. Workshop Session 2 years ago by Dr. Abner Notk ins. chief. 4:30 p.m.-6:30 p.m. Po ter Session 4 Laboratory of Oral Medicine. NIDR. Effons by Notkins, subsequent com THURSDAY, SEPT. 21 mi11ee chairpersons. the addit ion of the Alumni Symposium fi rst presented in 9:30 a.m.-3:30 p.m. Technical Sales Association (TSA) Scientitic 1990. and the NIH Special Projects Equipment Show Office headed by Flavin. have made the event a great success. This year. how FRIDA\ . SEPT. 22 ever. because of the newness or the sponsoring institute. NIOCD. there will 9:30 a.m.-2:30 p.m. Technical Sales Association (TSA) Scientific not be a Distinguished Al umni Equipment Show Symposium and Award. The booklet detai ling the linal sched Exhi bits located under the tents in Parking Lot 10-D. near the Clinical uling is now available. For more infor Center. mation call the NIH Visitor Information Center :11 (30 I) 496- 1776 or the NIHAA office at (30 1) 530-0567. 8 SUMMER 1 9 9 5 Calendar of Exhibits and Upcoming Events SEPTE'.\1UER-DECE:\-1BER This is a lecture series on health and Sept. 2 1 and 22-Technical Sales disease presented by NIH physicians Association Scientific Equipment "Here Today. Here Tomorrow: and sciemists sponsored by the Clinical Show Varieties of Medical Ephemera.'' an Cemer. NlH. The lectures are free and exhibit or printed medical ephemera held on Tuesday evenings beginning at OCTOBER from the collections of Wil liam H. 7 in Masur Auditorium, Bldg. 10. For Helfund and the Nat ional Library of more in format ion call (30 I) 496-2563. On Oct. 12, "The First NIH Medicine now on display in the front Postdoctoral and Clinical Fellows lobby of NLM (Bldg. 38, 8600 SEPTE:\1BER-'.\1ARCH 1996 Symposium.'' a day-long program fea Rockville Pike) until Sept. 11. turing 7 nationally recognized scien Opening later in September will be an The Foundation for Advanced tists from a diverse range of biological exhibit on "Medicine in India in the Education in the Sciences. Inc .. will disciplines. will focus on the latest ineteenth Century.'' The exhibit will sponsor eight concerts in the 1995-96 developments in molecular biology. feature photographs. books and memo season. especially those that contribute to an rabilia from the NLM and the collec Sept. 17-Richard Goode. piano underst;rnding of the etiology of major tion of Dr. Kenneth Robbins. For more Oct. 8-Pamela & Claude Frank. diseases. It will be held in the Natcher informat ion call the History of violin and piano Auditorium from 8:00 a.m. to 5: 15 Medicine Division, NLM, (30 I) 496 Oct. 22-Raphael Ensemble p.m. This program is sponsored by the 5405. Nov. 19-Pamela & Claude Frank NIH Office of Education and the NIH Dec. 3-Yenneer String Quartet Fellows Committee. For more infor SEPTEMBER-'JOVE'.\lBER Feb. 4-Radu Lupu. piano mation call (30 1) 496-3887. Mar. 3-Ysaye String Quartet Medicine for the Public: Mar. 17-Pamela & Claude Frank Oct. 10-AIOS: Can We Boost the Oct. 12. recep1jon in honor of Or. Immune System? Concerts are held on Sunday at 4 Maxine F. Singer. recipient of the 19<)5 Dr. Joseph Kovacs. p.m. in Masur Auditorium. Bldg. 10. NlHAA Public Service Award. 11 will NIH- CIinical Center Tickets are required. For more infor be held at the Mary Woodard Lasker Oct. 17- Melanoma and the Suntan mation call (30 I) 496-7976. Center (the Cloister). Bldg. 60, on the Generation grounds of the NIH campus, from 5:30 Dr. Stephen Katz SEPTEMBER p.m. to 7:30 p.m. Details will be se nt NIAMS and NCI to members in September. Oct. 24-Sickle Cell Anemia: cw Treatments and the Search for a Cure The First Robert S. Gordon Lecture Dr. Griffin Rodgers will be Wednesday. Sept. 13 at 3 p.m. * * * in Masur Auditorium. Bldg. 10. The NIDDK There is a series at NIH ca lled the Oct. 31- Understanding Infertility speaker will be Dr. Charles Hennekens who will speak on "Aspirin in the Wednesday Afternoon Lectures. held and the Ovary at 3:00 p.m. in Masur Auditorium, Dr. Lawrence Nelson Secondary and Primary Prevention of Cardiovascular Disease." This is an Bldg. I0. For info1111ation call Hilda NICI-I D Madine at (30 I) 594-5595. Nov. 14-Drug-Resistant Bacteria: annual NIH epidemiology award to rec Old Foes wi th New Faces ognize and honor a prominent epidemi ologist/9linical trialist. Dr. David Henderson For more infom1ation about various NIH Clinical Center lectures and events m rrH. call (30 I) Nov. 21 - Depression Research Festival ·95 Sept. 18 and 19-Symposium. 496-1766. For more infon11atio11 about Dr. Philip Gold NIHAA call (301) 530-0567. NIMH Poster Sessions. Workshops. Picnic 9 N I H A A UPDATE News From and About NIHAA Members and Foreign Chapters Dr. Cosimo Ajimone-Marsan, chief Dr. Bruce A. C habner recently retired Hope National Medical Center in of the Electroencephalograph y & from the ational Cancer Institute after Duarte, Calif. In 1990 he became Clinical Neurophysiology Branch. 23 years. He first joined NCI in 1967 director of Lhe Hagedorn Research 1954-1979. is now professor of neurol as a commissioned officer and clinical Institute in Copenhagen. Denmark. a ogy. Universi1y of Miami. School or associate. He served as director of basic research institute devo1ed to dia Medicine. department of neurology. NCl's Division of Cancer Treatment betes research. afliliated with 1he dan and head of the EEG Laboratory. since 1982 and retired as a rear admiral ish pharmaceutical company Novo Jackson Memorial Hospilal. He recent in the U.S. Public Health Service. ln ordisk. He is also professor in the ly published in the Joumo/ ofC/i11ical June he became chief of hematology sciences faculty at the Catholic Neurophysiology 12(1):46-56, an histor and medical oncology at Massachusells University of Lou vain in Belgium. He ical anicle entitled '"National Institute General Hospital Cancer Center in recenlly won the 1995 Quinquennial of Neurological Diseases and Stroke. Bos1on. Joseph Maisin Scientific Prize in National Jns1i1u1es of Health: Clinical Biomedical Sciences from the Belgian Neurophysiology and Epilepsy in the National Fund for Scientific Research First 25 Years of Its Intramural Dr. Pierre De Meyts came to NIH in for his work on the structure and func Program... A ddress correspondence January 1973 as a Fogany .International tion of insulin and growth hormone and reprin1 requests to Dr. C. Ajimone Postdoctoral Fellow 10 work with Jesse receptors. The prize. which carries a Marsan at 5895 SW I 17th St.. Miami. cash award of about $80.000 U.S. dol FL 33 156-5007, U.S. lars. was given a l an o fficial ceremony by the King of Belgium in Brussels on July 5. 1995. Dr. Serena M. Bagnasco, who wa-; a visiting associate in the Laborat ory of Kidney and Electrolyte Metabolism , Dr. Sara Fuchs repons that 1he N IH NHLBI. from 1982 to 1987, is now in Alumni A ssociation or Israel will the department or pathology and labo sponsor the lirst Christian B. Anfinsen ral ory of medicine at Emory University memorial lecture on Nov. 16. 1995. at School or M edicine in Atlanta. the Weizmann Institute or Science. Dr. Harold Varn1 us. IH direc tor. has agreed to speak. " A nfinsen's students Dr. Paul Calahr esi, who was a field and friends feel his loss very much ... investigator al Cl from 1956 to 1960. i. professor and chairman emeritus. department or medicine at Brown Dr. Harry A. Gailis, who was a srnff University. He has been named to the associate in Lhe Laboratory of President· s Cancer Panel. He also was Microbiology. IA ID. from 1968 to recently elected president of Lhe New Roth in the Clinical Endocrinology 1970, writes that he is " currently on England Cancer Society. having served Branch, where he developed the con the faculty in Internal Medicine at on the executive commi11ce of 1he soci cept of negative cooperativity in insulin Duke University School of M edicine:· ety since 1992. and was president-elect binding. He became a visiting associ His current research interests and last year. He also has received the St. ate in 1975. In July 1976. he went back research are administrative clirect0r or George M edal from th e American to the International Institute of Cellular the Duke AIDS Clinical Trcaiment Cancer Socie1y ational Division. T his and Molecular Pathology in Brussels. Unit ( IH-ACTG): director of Clinical award is given to ACS volunteers for In 1986. he left 10 become director of Research at Duke Center for AIDS distinguished local service and 10 of 1he department or diabetes. endocrinol Rese arch. and direc1or. antimicrobial the awards have been given since 1965. ogy and metabolism at the City of evaluation unit. 10 SUMMER 1 9 9 5 Dr. Thomas Q. Garvey, Ill, a research been professor of surgery and chief of associate at NCI from 1969-72 and a the division of oncology since joining guest investigator at NIADDK. 1976 the Miami faculty in 1974. He had 81. is now a clinical professor at served at the National Cancer Institute George Washington University from 1957 through 1974. first as a sur Medical School. He and his wife, gical investigator under Bob Smith. the Carol Wilson Garvey. have moved their first chief of surgery al NCL then pro practice into 1he univcrsi1y health plan gressing to chief of the Surgical Branch facility in Rockville, Mel. She will of NCI in 1962. He was also appointed teach in GW's new family practice resi clinical director of the National Cancer dency program. while he. in addition to Institute in 1970, a position he held maintaining his practice. continues as a until re1i ring to a second career at the consultant on drug development to Lhe University of Miami. pharmaceutical incluslry. Dr. Edwin H. Ko l od n ~· , a special fel Dr. Leonard G. Gomella, a medical low. Laboratory of eurochemistry physics group in 1973. From 1987 to staff fellow in the Surgery Branch at (Dr. Roscoe Brady). NINOS. from 1990. he was a scientist at the Naval Cl from Jul y 1986 to Ju ne 1988. has 1967 to 1970. fom1erly was the director Medical Research Institute. Bethesda. recently been named the first ··Bernard of the Eunice Kennedy Shriver Center Mel., and from 1990 to 1994. he was a W. Godwin. Jr.. Associate Professor of for Mental Retardmiol} in Waltham. patenr examiner at the U.S. Patent and Prostate Cancer·· at Thomas Jefferson Mass. Since 1991. he has been the Trademark Office, Arlington, Ya.. in University in Philadelphia. Bernard and Charlorre Marden profes the pharmaceutical part. sor of neurology and chairman of the department of neurology at New York Dr. Bernadine P. Healy, former direc University School of Medicine. He Dr. Alfred S. Ketcham reports Lhut tor of NI1-1 from 1991 to 1994, has been received the Solomon A. Berson ··having completed 38 years as a surgi named the new clean of the Ohio State Mecl ic;LI Alumni Ac hievement Award cal oncologist. r retired from the faculty Universi1y Co ll ege of Medicine. Healy in Clinical Science from NYU School at the University of Miami School of will srnn Sepl. 25. "This is a major of Med icine in 1993. He is also co Medicine on Apr. 30, 1995." He had commitment and an opportunity to lead author with professors Raymond an ins1itu1ion into 1he next centu ry,•· Adams and Gilles Lyon of the forth said Healy in an interview in the coming second edition of The Cleveland Plain Dealer. OSU's Neurology oflnherired Merabolic College of Medicine has an enrollment Diseases ofChildren. of about 900 s1udents and more than 1.000 full- and part-time faculty. Dr. Art hur Kornberg, a current 1 IGMS grantee who won Lhe 1959 Dr. Gregory R. Hook, who was an Nobel Prize in physiology or medicine. NIH staff fellow from 1982 to 1987. is is an emeritus professor in the bio an attorney with Campbell and Flores chemistry department of Stanford in San Diego. Calif.. specializing in Universit y. He was at IH from 1942 biotechnology patent law. He writes to 1953. Recently he received the 1995 that he received his JD in 1993 from Cosmos Club Award ··in recognition of George Mason University Law School. his internationally renowned contribu He received his Ph.D. from the ti ons to defining the role of chemistry Uni versit y of California. Berkeley. bio (See Members p. 12) 11 N I H A A U P D A T E in 1986. I worked as president of the Re1•ersi11g F({1y Years o.fG01•e1w11e111 Members (co111i1111ed.fim11 p. 11 ) Medical Research Division of Sernrity Failure. The book de1ails no1 in understanding life:· He also was American Cyanamid Co. from 1986 onl y a half centu ry of spies and traitors. selected to receive the Gairdner until I reached age 65 and retired in and their exploits. but the reasons and Foundat ional lnternational Award for December 1993. Since 1hen. in addi circumstances that made their actions his con1riburion 10 the understanding of tion to planning our new house. selling possible. An interesting feature of his DNA synthesis. He is one of three the old one and moving. I work as a book is the foreword wri11en by John A. recipients of the award. In October pan-time research consultant:· Walker. Jr .. the convicted spy who is 1995, during a ceremony in Toronto. serving a life sentence after his convic Canada. he will receive $22,500, a ti on for stealing and selling U.S. secrets fram ed inscription and a sculplUre. Dr. Karen (Chayt) Marcus, who was 10 the Soviets over a period or 18 years a clinical associate at Cl Pediatric whom Morse interviewed. Morse is Branch from July 1983 to June 1986. is also the president and publisher of an Dr. Thomas J.A. Lehman, a medical now at the Dana-Farber Cancer eleven-volume series of Preci.1· of staff fellow with NIDDK from July Institute. She writes "an update or Ojjicial Catholic Teaching that are 198 1 10 June 1983. reports that he was where I have been and what f have summaries of Papal encyclicals. and recently promoted 10 professor of clini been doing since leaving the Cl other documen1s or the Magisterium or cal pediatrics at Cornell Universit y Pediatric Branch. In July of 1986. after 1hc Catholic Church. They are now Medical Center. comple1i on of my NCI pcdia1ric oncol se nl th roughout the Catholic world for ogy fellowship. I began a residency in use by seminaries. bishops. Papal radiatfon oncology at Harvard Medical uncios and others. Morse and his Dr. Arthu r W. Merrick, who was a School's Joint Center for Radial ion wife have been cited by the Pope on a health sc ience adminis1rator a1 NHLBI Therapy (JCRT). Upon completion of number of occasions during Papal audi· from 1972 10 1985. writes that he is 1hat training in 1989. I was invited 10 ences ar tbe Vatican. sorry to hu ve missed the ··annual meet join the JCRT facu lt y where I have ing and picnic ... my wife, all fi ve off remained. I am di vision chief of radia spring (from Montana, Kansas. Oregon. tion oncology at the Dana-Farber Dr. Donald L. Morton, who was at and Maryland) ... wi ll be in Santa Cancer Institute and an associate in Cl from 1960 to 197 1. is now medical Barbara. Calif.. winding down a cele radiation oncology at the Boston dircc1or of the John Wayne Cancer bration of our 501h wedding anniver Children's Hospital. I am an assistant ln ~ lilllt e . Santa Monica, Calif. He was sary ... I marvel at the incredible pro professor of rad iation oncology at recently presented the Uni versity or fess ional beginning of 1he NIH AA and Harvard Medical School. I am also Texas M.D. Anderson Cancer Center's 1J1e newsleuer. All of your hard work very active in the pediatric oncology Jeffrey A. Go11lieb Award for his work obviously will reap great dividends.'' group and am on the executive commi1 in surgical oncology and immunothern 1ee for the radiation oncology disci· py of solid tumors. pline. In 1990. I married Michael Dr. Harry M. Meyer, who was an Marcus. who was originally from NIH/FDA scien 1is1 from 1959 to 1986. Manchester. England. We li ve in Dr. Raj K. Narayan, who was n spe writes 1ha1 "My wife and I moved from Brook line, Mass .. but make regular vis cial expert. NINDS. Surgical our longtime home in 1he Washington, i1s to Israel where Michael's famil y has eurology Branch. July 1982 10 June D.C. area 10 San Juan ! ~ land in li ved since 1973 ... 1985. has reccn1ly been named profes Washing1on State th is spring. We are sor and chainnan, department of neuro· building a new home on the wes1 side surgery. Temple Uni versit y Hospital. of 1he island looking over the Haro George " Pat" Morse, who was at NIH Philadelphia. Prior 10 that he was a Strait at Vancouver Island. some eight as head or Protection and Safety professor of neurosurgery at Baylor miles away. It is the be.;1location in Managemenl. 1955-1970. is now direc Coll ege of Medicine in Texas. chief of the 50 states to whale-wt11ch. Orcas tor of his own company that consulls in neurosurgery at Ben Taub General sw im right into our cove. After retire protection. Recently he has wriuen a Hospital and auending neurosurgeon at ment from Pl-I S afler 31 years service book. America. Twice Betrayed Methodist Hospital. 12 SUMMER 1 9 9 5 H. Kenneth Painter, who was at N IH membrane. Studies to elate are quite affairs . U.S. from 1946 co 1978. is now retired. He encouraging. and my guess would be Human identified one of th e people (middle of that at least two polyurethane condoms Heahh. the second row) in th e photo on p. 38 of will be on the market within a year or M erck & the Spring 1995 Updc11e as James two. Other ac1ivi1ies included interac Co.. and r ·Ji111111{» Marshall. who worked as a tions with the FDA 10 develop appro adjunct pro laboratory 1echnician in 1he a1ional priate study protocols for both premar fessor of Microbiologica l lnsti1ute. In May ket testing and po tmarkel 1es1ing of medicine. 1995. Painter was the subject of an barrier co111racep1i ve devices. especial University interview in the Be1fte.wla Ga: e11e l y those intended to prevent sexually of Pennsyl reca lling his experiences as part of an transmiued diseases." vania. He Allied unit that liberated Dachau. was chair man. department of medicine. A lbert Dr . Saul A. Schepartz reports that on Einstein College of M edicine before Or. A urora K. Pajean, who was a ··oec. 30. 1 99~ . I retired from my posi going 10 M erck in 1987. clinical associate in 1he Neuroepidemi tion as deputy associate director for the ology Branch. NIN OS. from 199 1 to NCI Developmental T herapeutics 1994. is now in the neuroepidemiology Program and am s1art ing a consulting Dr. Lawrence Shulman, who recently unit. cerebrovascular !.ection at 1he activ i1y from home. Altogether, I spent retired as director of NIA MS. has been eurology-Rush M ed ical Cen1er in over 3 1 years at Cl. 1958- 1995 (I was appoi111ed dircc1or emeritus. He i!, now Chicago. away in academia. 1984-1989). .. serving as the IH direc1or·s emissary to the clinical research community. Recently he was hono1,ecl by two Dr. Barbara L. Parry, a senior staff Dr. S. Stephen Schiaffino, who was groups: The American Academy or associate in clinical psychology. deputy director of DRG and then senior Dermatology (A A D) and 1he IMH. from July 1982 to Oc1ober science advisor for Ex1ramural Orthopaedic Research Socie1y (ORS). 1985. writes th ai she recently received Programs. OD. 11-1 . until his retire The A A D organized a symposium from ..the ational A lliance for ment in 1987 . rel ired last year from his ti tled ..Wha( s cw and Ho1 in Clinical Research on Schizophrenia and posi1ion as execu1i ve officer of the Research'? A Tribute to Lawrence E. Depression. an award for established A merican Society for Clinical Shulman. M.D:· where accolades were inves tigators. Nutrition. He is currently a volunteer presented by rcpresenlatives or medical at the N ational Museum of Health and centers and major dermarology organi M edicine located on the campus of 1he zation . . The ORS dedicated 1hc trans Or. Dolores J. Patanelli who was at Waller Reed A nny Medical Center. He actions of i1s 4 l st annual meeting to lCHo·s Center for Population reports .. the museum is urgently in need Shulman and to Ileen Stewart. who Research. Contraceptive Branch. writes of clocems (lour leaders). A nyone recently retired from her position as thut. .. while ut N JCHD, I wus re~ po n s i interested in 1he volun1eer activity !>C ientific review adminis1rator in ORG. ble for implementing an extensi ve pro should call the direc tor of volunteer ORs·s dedication to Shulman stated gram for the development and clinical activitie. a1 the museum (202) 782 !hat '·during his tenure as NIAMS testing or new and improved barrier 220 1) for infonnaiion. Several N IH Director. Dr. Shulman ·uccess fully contraceptive . l was projec1 officer on alumni are currently serving as volun guided 1he development of 1he Institute clinical studies that led to the FD A teen; ai 1he museum.·· through its formative years. He played approval or 1he T oday Con1raceptive a pi votal role in facilitating 1he growth Sponge and the Cervical Cap. Before of both the intramural and extramural leaving NIH. I initiated studies wi1h Dr. Louis M. Sherwood, who was al research area of the Institute by devel condoms made from polyurethane N IH as ·a clinical associa1 e working oping new programs. encouraging polymers. A n impon ant issue in these with Dr. John Polls. National Hean innova 1ion. and seizing scien1ific s1udies is 1he accep1abili1y of the lnsti1u1e. 1963-1966. is currently senior opportuni tie:-.:· polyureth ane polymer :-. as a condom vice president. medical and scientific (See Membersp. l../J 13 N I H A A UPDATE Members (co11ti11uedfro111 p. 13) who analyzed SEER data on frequency. Dr. J. Craig Venter, who was chief. incidence, and survival by cell type and receptor biochemistry and molecular Dr. Marc A. Sil ver, who was a med cancer site. biology section. NINOS. from 1987 to ical staff fellow in the NHLBI 1992, is now director of the Institute of Pathology Branch from 1982- 1984, is Genomic Research. Gaithersburg. Md. now with the Henri Failure Program at Dr. John P. Utz, chief, infecti ous dis Recently he was feat1ired in a cover Loyola University in fllin ois. He has ease service, NIArD. 1952-1965. and story in Business Week. May 8. 1995. recently published a book (Plenum) currently professor emeritus. School of He also received wide coverage for his about congestive heart failure wrinen Medicine. Georgetown University, deciphering of the entire DNA for patients and families titled: Success Washington D.C .. has moved to sequence of the bacterium. Hemophilus with Heart Failure. Naples, Fla. He continues 10 serve on influenzae. a feat never before achieved the boards of directors for: National in a free-living organism. Foundation for Infectious Diseases. Dr. Charlotte Silverman, who was al National Institutes of Health Alumni NIMH from 1962 10 1967 in the com Association and Data and Safety Dr. Barbara A. Ward, a clinical staff munity services branch in various posi Management Board, NLAID. fellow at NCI in the Surgery Branch tions. finall y becoming chief of epi from 1985 to 1987. has been named demiologic studies. received an Alumni director of the Comprehensive Breast Life Achievement Award from Dr. P. Roy Vagelos, senior surgeon Care Center at the Yale University Brooklyn College last year. and then head of the section of compar Cancer Center. She also is an assistant ative biochemistry, Laboratory of professor or surgery at the center. Biochemistry, NHLBI. from 1956 10 0 1· ••J ames A. Steele, who worked with 1966. is now chairman or the board of Dr. Charles Annstrong in brucellosis Regeneron Phannaceuticals. Inc. He Dr. Robert Warren, who was in the and infectious diseases from September recently joined the research advisory Medicine Branch, NCI, from 1974-77. 1945 to September l947. is now pro board of the lnstitut de Recherche recently has been named clinical affairs fessor emerillls at the University of Cliniques de Montreal. di rector of the Georgetown University Texas School of Public HealtJ1. Recently. he was involved with the editing of 1wo books: MycobaC1eri11m !JOis Infection in Animals and Humans that was publ ished by Iowa State University Press. and the second edi tion of Tlte I landl10ok of Zoonoses Section A: Bacterial. Rickeusial. Chlamydia. and Mycotic. Se('(ion 8: Viral. Dr. Harold L. Stewart, who has had a long and distinguished career at the National Cancer Institute since 1937, still works on campus as an NIH scien- 1isi emeritus. A special supplt:1m:nt of Cancer. Jan. 1.1995. issue. was dedi Rachel Thrasher, who from December 1958 to March 1978 was at the Clinical Center affili· cated 10 him. The monograph titled ated with NINDB, NIAID, and NEI, where she retired as head nurse, now lives at Asbury ''Histology of Cancer Incidence and Methodist VIiiage In Gaithersburg. She is very much involved In activities there as you see Prognosis: SEER Population-Based In the above photo (she is in back of the # 4) appearing in a production of Campus Capers. Data 1973- 1987," brings together 38 Other former NIH staff now living at Asbury include: Mary Daniel (NIMH), Dr. Robert Ing expens in pathology and epidemiology (NCI), Rachel Larson-Henry (NIDR), Dr. Donald M. MacCanon (NHLBI and DRG), Dan Rice (00) and Del Thrasher (NIDR and NIAMD). 14 SUMMER 1 9 9 5 Lombardi Cancer Center. Washington. A Message From the New NIHAA President D.C. In this newly created position. he will oversee cancer patient care ser On June I of this year. I vices and resources. replaced Thomas J. Kennedy. Jr.. as the president of the N IH A lumni Association. Other Dr. Gar y M. Williams, who was at new officers are William I. NCI in the Etiology Division. 1969- Gay. vice president: Joseph 1971. writes that the " April 15, 1995, Perpich. vice president: and cover of Cc11wer Research featured Dr. Storm Whaley. secretary. John Weisburgcr (NCI 1949-1972) and Harley G. Sheffield continues me for our work on mechanisms of car as treasurer. cinogenesis. We arc now at the I want to pay special tribute American Health Foundation. Valhalla. to Tom Kennedy who. during N.Y .. and recently were invited speak his two years as president. ers at the 2nd Conference of the emphasized by example how International Federation of Societies of the NIHAA can support the Toxicologic Pathology. in Tours. NfH within the constraints France. The conference focused on placed on 50 I (c) 3 nonprofit cancer risk assessment and its applica organjzations. T he necessity tion to sound regulatory policies:· for NIH alumni to speak out in suppon of the IH mission also was a theme of two of o ur Mar y Woodside, who worked at the speakers at the 1995 annual Clinica l Center in the department of meeting of the N IHAA. held pathology with Dr. George Williams. at the Mary Woodard Lasker Calvin B. Baldwin, Jr. from 1964 10 1974. reports that she has Center on June 10. 1995. Rep. finally been able to move back to Connie Morella sa id that while she is ti al successes would be lost.·· where she and her husband lived .. cautiously optimistic .. about th e fat e or As th e new president of NTH AA. I before Hurricane Andrew hit. .. I've the FY 1996 NIH appropriation now am :;orry to greet you with a message of been in East Ridge Retirement V illage under consideration. she is conce rned concern over the fiscal prospects for since Gilbert and I moved here in about ··everyone thinking th at NIH is NIH. This is very different from my January 1989. Hull"icane Andrew did a automatically protected.'. Dr. Robert experiences during 33 very happy years lot of damage. We had been evacuated Butler. former director of the National as an administrator at JH when the ahead of the stonn. But the church we Institute on Aging. stressed that the problem we often faced was how best were sheltered in was itself in line with IHAA should take the lead in helping to to use our increased appropriations. I the storm. so we were taken care of find additional sources of financial sup welcome any advice from our members but djdn"t miss the excitement!!! Our port for re earch ...As alumni:· he said. about how the IHAA can be an effec damaged apartments were emptied. .. we can be outspoken and maybe outra tive advocate for the fJH. things put in storage. and we were geous:· In a recent editorial in Science. The strength of our organization is in housed in a Holiday Inn in Delray Congressman John E. Porter. current its members. And. as one of the enthu Beach for five months: while we were chairn1an of the House Appropriation~ siastic founders of the IHAA. I am there. Gilbert had another stroke from Subcomrninee responsible for the I H. frankly disappointed at our inability to which he could not recover. It was notes that House and Senate budget com amact a larger membership. About February 1993 before I returned to East minees have recommended cuts in the 1.800 per ons have joined t11e 1 lHAA Ridge with the others. J"vc enjoyed N IH budget and .. that these proposed cuts since its inception in I 987: presently reading the N IHAA Updare. The news would be disastrous. Award rates would we have about 1.400 active members. and pictures helped bring me into th e drop. young researchers would choose That is a rather poor showing. consider- presen1.'· other careers. and momentum and potcn- ( See President's Leiter p. 16 J 15 N I H A A UPDATE President's Letter (from p. 15) Attention ing the 50,000 or more people who NIHAA wants to hear from its members. Please type or print your note for a future have at one time worked at N IH. issue and mail it to Update at 9101 Old Georgetown Rd., Bethesda, Md 20814·1616 A maj or problem is that NTH has nei ther a record of who has worked on the campus nor how former staff can be located. The NIHAA has offered to Name assist NfH is establishing a system of Home Phone maintaining the addresses of alumni which we believe could be of immea Home address surable help to both the NfH and NIHAA. Tom Malone. former NJH deputy director and currently ehaimrnn News, including dates/position at NIH and photo if possible of the NIH AA membership committee. and I have both had considerable suc cess in attracting members by simply writing or calling acquaimances to urge them to join. I urge you to do the same to encourage membership. We will be happy to assist any of you who are will ing to volunteer to help boost recruit ment. The past year has been a product ive one for the N IHAA. We have pub lished two copies or our newsletter. Suggestions to newsletter NIHAA Update. that have kept you informed about activities al NIH and individual alumni: Tom Kennedy test i tied for the N IH appropriation be fore the House A pproprimions Committee; Roy Yagclos was the sec ond recipient of the NI HAA Public Service Award: we assisted NIH in the 1994 Research Festival and held a reception for new clinical research associates; Tom Kennedy prepared an imponant paper, published in the Suggestions for NIHAA Updc11e. concerning curren t issues fac ing the N IH and the biomedical research community: and the N IHAA historical committee has contracted with N CH to conduct a campus-wide survey of historical objects and memo rabilia. The NIHAA board and officers welcome any thoughts you may have to make the association both more effec tive and attrnctive to its members. Please renew if you have not done so. 16 SUM ME R 1 g g 5 Science Research NIAMS and NIA to help understand cent of women with two or fewer risk who is at risk for hip fracture. factors. "A very small number of Update .. The finding that there are many women wiLh a lot of the risk factors Researchers Identify Hip things that a woman can do on her own plus low bone density account for most that may decrease her risk of hip frac of the fractures." Cummings said. "The Fracture Risk Factors ture is exrremely important," said Dr. six percent of women who had five or Michael 0. Lockshin. former acting more risk factors in addition to low By Dr. Elia Ben-Ari director of NIA MS . .. Also imporiant is bone density accounted for one-third of the idea chat in the future it may be pos the 192 hip fractures we observed dur A host or readil y identifiable factors, sible to identify specific women-and ing the study period." many of which can easily be modified, perhaps men-who are at especially Because many of these risk factors increase Lhe risk of hip fracture in older high risk for hip fracture, and target can be identified by a simple physical women, according 10 researchers par them for intensive prevention effor1s." examination and patient interview. they ticipating in the Study of OsteoporoLic '·Avoiding hip fracture is a life and can provide health-care practitioners Fractures (SOF). The study. funded by death issue for many older people. lt's wiLh valuable and easily obtained infor NlH , involves more than 9,500 women a devastating injury." said Dr. Richard mation that can help identify those age 65 and older and suggests that there J. Hodes. director of NlA. One of older women who most urgently need are a number of steps women can take every six white women will have a hip to take steps to reduce their fracture Lhat may decrease their fracture risk. fracture during her lifetime. Of the risk. These include staying active. walking more than 250.000 people each year Cummings and colleagues found that for exercise. gelling treatment for who have hip frac tures. up to 20 per a woman whose mother suffered a hip impaired vision. quitting smoking. cent will not survive more than a year. fracture has twice the risk of hip frac stopping use of cer1ain medications. Of those who do survive, many are left ture. and that this risk factor is indepen reducing caffeine intake, maintaining unable to walk and are forced to enter a dent of a woman's bone density. body weight and taking steps to main nursing home. '·Focusing on the pre "Everyone has believed that family his tain bone density, with estrogen replac vention of hip fractures is an important tory is impo11ant. but this is Lhe first emelll therapy or other treatments. element in our efforts to promote inde time anyone has shown that iL is in fact The researchers found that women pendence and an enhanced quality of important and just how important it is." who have five or more risk factors have life for older people,.. noted Hodes. said Cummings. "What's surprising is an increased li kelihood of suffering a Researchers at the fou r participating that if your mother broke her hip, hip fracture. Previous results from this clinical centers did tests for bone densi you' re at higher ri sk of breaking your group and others show that women ty and assessed other potential risk fac hip regardless of what your bone densi with low bone density have a greater tors through physical examint11ions, ty is... Cummings emphasized, howev risk of hip fracture. This new study questionnaires and interviews in 9.516 er, that "alLhough you can 't change finds that assessing risk factors in addi- older women who had no previous hip your family history. you can reduce 1ion 10 bone density further improves fracture. They contacted these women your risk in oLher ways. Taking pre the ability 10 predict a woman· s risk. at 4-month intervals for an average of cautions to reduce the risk of hip frac The results by Dr. Steven R. 4.1 years to detem1ine the frequency of tures is even more important for those Cummings of the University of Cali hip fracture. with a family history:· fornia. San Francisco (UCSF). and his The SOF investigators identified 16 0Lher factors that increa ed the risk colleagues at UCSF and four participat independent factors besides bone densi of hip fracture were poorer health as ing clinical centers in Ballimore. Min ty Lhat increased Lhe risk of hip fracture rated by Lhe women Lhemselves. a his neapolis. Piusburgh. and Portland. Ore. in older women. The effect of most tory of hyperthyroidism. a history of were reported in the Mar. 23 issue of individual risk factors was modest. but any other fracture since age 50 and the New England .loumal ofMedicine. together Lheir impact was substantial. therapy with anticonvulsants or certain SOF is a multicenter sllldy in which Fifteen percent of the women in the long-acting medications commonly over 9,500 white women age 65 and study had five or more risk factors (not taken for anxiety or insomnia. The above and not living in nursing homes including low bone density): these risk of hip fracture also increased with have been participating for 6 lo 8 years. women bad an 18 times greater occur caffeine intake. lack of exercise and The study is supported by grams from rence of hip fractures than the 47 per- smoking. 17 SUMMER 1 9 9 5 Office of Community Liaison Established by NIH In September 1994. Janyce Hedetniemi was appoinred first director of NIH's newly established Office of Communi ty Liaison, l located in I the Office of the NTH Director. Among her responsibilities arc : 1l the oversight and monitoring of activities such as: Nl1-l 's d i s po~a l ' of medica l and pathological waste; \ ~ -:i 1he development of NIH 's campu!i master plan, including construc tion and transportation issues: and improvement in the way NIH inter acts with people who live and work near NIH. Also. the office w ill be involved in the conduct of ongo ing and planned studies related to test ing of soil for possible envi ronmental impact, recycling pro grams, standards related to noise levels. "green" buffer zones on the campus perimeter. and projection of NIH employment growth. The oflicc will interact with res idents of the nearby community, the neighborhood advisory groups, • SEAV CE.SUPP RT the regulmory. appointed and CLINICAL ClR EXPANSIO• ' t2N ?ARKl '~G elected bodies that advise and govern M ontgomery County, the LABORATORY REPLACE'vlEl'iT Ft\CIL TY State of Maryland, the National OfflCEJAC:/.11:, Capital Planning Commission, and RES oe~mAlJSPEC Al Fu~CTION members of Congress. On Mar. I, the office held ANIMA FAC L TY 1 1995, an NIH-Community Foru m to dis cuss issues and set an agenda to This Is a drawing of the preliminary master plan for the Bethesda ca mpus of NIH. Sketched promote and maintain communi by consultants to the Office of Research Services, it represents a vision of what the cam cation between NlH and the pus could look like in 2015. A final , approved version of the plan is expected by the end of neighboring communities. 1995. 19 N I H A A UPDATE 'Iron Man' ( comi1111ed jiwn p. 21) There·s not a window in it that you can raise. Friends of the DeWitt Stetten, Jr. Jennings once went on a stretch of 32 Museum of Medical Research at the years without a grade change. Most of National Institutes of Health his former supervisors he has not only outworked. but also outlived. He still hears from one. however- Dr. Victor "Medicine Now and in rhe 21st Century" Haas, who retired in 1957 from the Laboratory of infecti ous Diseases. Holland American Lines ·'His wife writes me a card every Dr. DeWitt Stetten, Jr. Eastern Caribbean Cruise Christmas," Jennings said. ·'She said Feb. 17-25, 1996 Dr. Haas doesn ·t get around as well as I do. I'm real lucky. I'm glad 10 have a-; Dr. C. Everett Koop, many friends as I do and l"m glad to Keynote Speaker. Re1ircd Surgeon General of the United Srates have a job. 'The only advice I can offer to young Dr. Robert N. Butler people is to srarl now by changing your Former Direc1or. National lns1i1u1e on Aging. NIH auitude. Gel a job and stay with it. Curren1ly Chainnan of the Dept. of Geria1rics Don't ever give up. A person that Mount Sinai School of Medicine. New York City. N. Y. gives up is beat before he stans. The life you live is the life you die. Dr. Kurt Isselbacher Working never hurt anybody. I have a Direc1or of Massachuse11s General 1-lospiml (MGH) lot or faith and when I die I want the Harvard Medical School Cimcer Center Lord 10 say yo ur job has been well Previously Chief of the Gus1rocn1erology Uni1 of MGH done." On June 13. Jennings was honored as Dr. Seymour Kety part of the IH Director's Awards Fonner Scien1ilic Direc1or of 1he Na1ional lnstitu1e of Mental Heahh a1 NIH Fonner Chainnan, Dept. of Psychia1ry. Johns Hopkins Univer~i1y School of Medicine Ceremony. Curren1ly Profc~sor Emeri1us of Ncuro~cicncc. Dept. of P~ychiatry. Harvard Medica l School Curren 1l y Senior Scicn1ist. lnrramural Research Program. National lns1i1ute of Mental Heal1h. NIM Dr. P. Roy Vagelos Former Chief Execu1ive Officer of Merck & Co. If you are not a life Fornier Chairman of 1he Depr. of Biochemis1ry. School of Medicine. Washing.ion member, you have Univcrsi1y. Sr. Louis. Missouri received a dues no tice Curren1ly Chairman of 1he Board of Trus1ees of the Universi1y of Pennsylvania from NIH AA. Dues are an importan1 source of Marshall Loeb our income and we need Editor al Large Fortune magazine your continued support. Former Editor Money magazine Also check your address label. If it says .. member Sail the Eastern Caribbean- Holland America's \Vesrerdam ship expired'. please Departing from Ft. Lauderdale. ca ll at Philipsburg. S1. Maarten. St. John, U.S. renew promptly or this Virgin Islands. St. Thomas. Nassau. Bahamas and rewrning 10 Ft. Lauderdale wi ll be your Ima newslet- 1er. Proceeds will benefit the Steucn Memorial Fellowship in the History of 201h Century Biomedical Sciences and Technology. For more information call 1-800-926-3775 or write to: Continuing Education. Inc., 6800 Gulfport Blvd. S.. #103. South Pasadena. FL 33707 22 SUMMER 1 9 9 5 Clinical Center Town Meeting Addresses Budget Realities By Sara Byars it"s not 10 close it. It's to make it from the impact of all these events ... stronger. make it belier," Callin said. "The Clinical Center is the world's How do we cope with today's federal "And we will look at all alternatives largest hospital devoted to clinical budget realities while continufog ser that are needed to do that." research and an invaluable ac;set to the vice as the country's onJy hospital ··our aim is ... to lind methods, to naiion." HHS Secretary Donna Shalala devoted entirely to clinjcal research? find legal flexibilit y." added Smits, "ro said in a May I I broadcast message to Thal 's 1he essential question sur let this place be for the next 25 years employees . .. However. ri sing costs at rounding lhc Clinical Center today, and just as great as it's been for the last 25 the Clinical Center have forced us to it topped the agenda at the June 7. because you've got a lot of very impor scale back some of our research pro 1995. town meeting. tant work ro do.·· grams. To preserve. protect. and Dr. John Gall in, CC director. shared Medical and scientific discoveries strengthen our research we have to the podium in Masur Auditorium with that have unfolded and are being devel minimize overhead and hospital operat Dr. Helen Smits. deputy administrator oped at the CC have revolutionized bio ing costs." of the Health Care Financing Admini medical research and clinical care in The second phase of Vice President stration, who chairs a CC Options everything from cancer to infectious Gore· s reinventing government initia Comm ii tee looking for ways to help the diseases. "At the same time," Gallin tive. dubbed REGO-LI , fuels this dri ve Clinical Center 10 do its vi tal business continued. ·'our government is in the for increased effi ciency at the Clinical beucr. midst of the most drnmatic fisca l crisis Center. But. there wi ll be no quick and "The incentive is 10 improve the of our lives. and the NIH and the global fix. Clinical Center. It 's not to dismantle it, Clinical Center will not be immune .. Yes. we will be looking at whether contracting out portions of the Clinical Center is a wise direction:· Gall in explained . .. But. we wi ll not do any thing if it can't be shown to be cos1- effecti ve and if we can ·1 clearly con vince ourselves that the recommenda tions will result in a better research enterprise. Contracting out 1he entire Clinical Center would clearly, in my opinion, disrupt the delicate and valu able relationships between the Clinical Center and institute staff that makes our facility ~o special and so successful. '' '·Remember. half- 50 percent--of your budget.'' added Smits. "is not per sonnel costs. It 's other costs. It's pos sible to find tremendous savings in there which help become the cushion that allows you to maintain the employ ment, retain good staff, and keep good people here.,. Options team members will scrut i nize how other similar institutions Dr. Helen Smits, who heads a committee looking for ways to make the CC operation more operate to help detem1ine strategies for efficient, Joins Dr. John Galin, CC director, at the podium during June 7 town meeting to savings that would work here. update employees on future directions. ' (See Clinical Center p. 2./) 23 N I H A A U P D A T E Atl 24 SUMMER 1 9 9 5 murnl programs a1 Nn-1 ... Or. Ronald P. recen1ly honored with the Kitrl Spencer and served from 1987 to L993 as chief of Mason, a research chemist al NIEHS, has Lashley Awm·d by the American the Epidemiology Branch in NIAAA 's received 1he American Chemical Society's Philosophical Society, for "brilliant techni Division ofBiometTy and Epidemiology. 1994 SouLhern Chemist Award. The prize cal innovations in recording the activity of Among her special research interests are confers a gold medal and an award and rec single visual neurons of alert behaviorally alcohol-related morbidity and mortality, ognizes distinguished service 10 1he profes trai.ned monkeys that made possible salient especially alcoholic liver disease. breast sion. Mason, on the staff of the Laboratory scientific discoveries relati.ng individual cancer, alcohol liver d.isease, breast cancer, of Molecular Biophysics. has been among nerve cells to visual perception and the gen alcohol and women, ;ilcohol and nutrition, lhC pioneers in !he application of elecLron eration ol' eye movement." and risks and benefits or moderate alcohol spin resonance techniques to biochemical, consumption ... Or. Chhanda L . Ganguly, pharmacological. and 1oxicological prob formerly a scientific review administrator lems ... Or. Bernard Moss, chief of APPOINTMENTS AND (S RA) al NCRR and a senior srnff fell ow at NIAID"s Laboratory ol' Viral Diseases, PERSONNEL CHANGES N HLBL, has joined the Division of received 1he 1994 ICN International Prize in Research Grants as a SRA for 1he biochem Virology, consisting of an award and istry s1Udy section ... Michael Goldrich has $50,000. The prize recognizes Moss·s Or. Normann. Anderson has been named been named NIAID's deput y director for many fundamental conLributions to knowl lo the newly established posit ion of NIH management and operations. Prior to 1hc edge of vaccinia virus-well -k nown for i1s associate director for behavioral and social appointment he was the executive officer role as the vaccine tlrnt eraclica1ed small sciences research. He was an associate pro for the insLitu1e ... Dr. Patricia Grady has pox-and for the worldwide impact of his fessor in the departments or psychiatry and been named to head the National Institute of research ... Or. Roberl Nussenblatt, direc psychology: social and heahh sciences al Nursing Research. She had been 1he NINOS tor of NEl's Division of Intramural Duke Un iversity. He is also founder and deputy director and is nationally recognized Research. received a docte111· honoris ca11sa di rector of Duke's Program on Health, for her broad academic and clinical research (honorary doctor of science degree) from Behavior, and Aging in Black Americans background and experience in conducting the Universit y of Paris. Prance, in recogni and director of Duke's Exploratory Center and managing neurological research ... Or. tion of his lifelong work in imraocular dis for Research on Health Promotion in Older Stephen I. Kal:t., chief or the Dermatology eases ... Dr. ,Joost ,J. Oppenheim, chief of Minori tie~ ... Colleen Barros, chief admin Branch, NCI, has been l):lmed director of the NCI Laboratory of Molecular istrative officer for the Office of the the National Institute of Arthritis and lmmunoregulation in the Biologica.I Director, NlH. for the last 6 years , has been Musculosketal and Skin Diseases. An inter Response Modifiers Program, was recemly named executive officer for the National nationally known dermatologist and immu honored during a 2-day "festschrift" inter Institute on Aging ... Or. James Battey has nologist. he succeeds Dr. Michael D. national symposium on "Cytokines and been named director of the NIDCD's Lockshin, acting director, NIAMS, and Dr. Chemokines·· convened in his honor in Division of Intramural Research. He came Lawrence E. Shulmim, the first and found Lubeck, Germany. He was honored for his to NTH in 1983, firs1 on the staff of the ing director of the instilUte who reti.red. research accomplishments and his role in National Cimcer Institute, where he rose Katz wiJI maintain his branch at NCJ ... Or. training young scientists in immunol ogical from senior s1aff fell ow to senior investiga Thomas J. Kindt, chief of N1AID's research during hi s more thitn 30 years at tor. In 1988, he moved to NTNDS as chief Laboratory of lmmunogenetics. has been NlH ... Donald R. Shoplancl , coordinator of the molecular neuroscience section in the appointed director of the Division of of NCl 's Smoking and Tobacco Control Laboratory ofNeurochemistry. [n 1992, he Intramural Research at NTAJD. succeeding Program, was recently awarded the 1995 returned to NCI to head the molecular struc Dr. John Gallin. He has long been recog Joseph W. Cullen Award. He was honored ture section of the Laboratory of Biological nized for his expert ise in 1he field of with the Cullen Award i.n recognition of his Chemistry and became chief in 1993 ... Or. immunology and has made seminal contri lifelong contributions to lhe field of smok Anne Bavier has been named deputy direc butions in understanding human T-cell ing and tobacco ... Or. Cynthia Sung, a tor, Office of Research on Women 's Health, leukemia virus- I ... Or. Matthew Kinnard senior staff fellow wi1h the National Ce111er OD ... Evelyn R. Burrell was recently recently assumed the role of director of the for Research Resources, has recently been appointed chief, Administrative Extramural Associates Program within the named one of Maryland's Distinguished Manageme111 Branch, Division of Office of Extramural Research, OD. Young Engineers for 1995. She received the lntramural Research, N.ICHD. This office Established in 1978, EAP provides opportu award for her abil it y to apply engineering provides services and support to NICHD's nities for greater awareness of and panici principles to the problems of drug delivery Imramurnl Research Program ... Or. pmion in PHS-sponsored biomedical and in 1he body as well as for her academic Richard .J. Davey, who served 1he Clinical behavioral research ill minority and accomplishments and professional integrity Center's department of transfusion medi women's institutions throughout the coun ... Or. Federico Welsch, associate director cine as chief of the laboratory services sec try. He comes to EA P from NlDR where he for in1erna1 ional affairs, NCI, received from ti on. lcfl recentl y 10 become chief medical was director of the oral soft tissue diseases the Slovak Academy of Science the officer ot the American Red Cross ... Dr. and AIDS research area ... Or. Richard 0. Johannes Jessenius Medal of Honor for his Mary C. Dufour has been named deputy Klausner has been named director of 1he support or cancer research in Slovaki a ... director of the National Institute on Alcohol National Cancer Institute. He has been Dr. Robert Wurtz, chief of NEI's Abuse imd Alcoholism. She is a nationally chief or 1he Cell Biology and Meiabolism Laboratory or Sensorimotor Research. was recognized expert in alcohol epidemiology Bnmch of N ICH D si nce 1984. He is •m 25 N I H A A UPDATE interna tiona ll y recogni zed scientis1 who has grants associates board, and the STEP pro California School of Demistry. He Ors. J. E. Rall (c) and Jacob Robbins (r) were both honored with a special sympo sium entitled "Celebrating the Mentors: The Global Village of J.E. Rall and Jacob Robbins." They are shown here with Dr. Phillip Gorden, NIDDK direc tor. The symposium was held on June 17 in connection with the Endocrine Society annual meeting, held this year in Washington, D.C. Rall began his 40- year NIH career as chief of the Clinical Endocrinology Branch. He later became NIDDK scien tific director for 21 years and in 1983 was named NIH deputy director for intramural research, where he served for the next 8 years. Robbins followed Rall as chief of CED and led the scientific achievements of the branch for 28 years. Together, Rall , Robbins and collabo rators performed fundamental studies of thyroid function and pioneered the use of radioactive iodine in the treatment of thyroid cancer. Both Rall and Robbins recently retired and are scientists emeritus at NIDDK. Rall and Robbins are holding charcoal portraits done by Al Laoang, NCRR, which were presented to them at the symposium. 26 SUMMER 1 9 9 5 cies to deal with Capitol Hill's evcrchang she became professor and chief of 1hc unit Business Lnnovation Research Applications. ing environment ... Dr • .Janna Wehrle on neurovirology and regeneration of the He plans to travel and spend time in the recenLly joined the swff of NIGMS as a nervous system at the Pasteur Institute in library on research projects... Or. Za\!en health scientist administrator in the Division Paris. Frnnce ... Dr. .J er ome G. Green Khachat urian, associate N IA director for of Cell Biology and Biophysics. Prior to recently reLired after 40 years at NII-I. For neuroscience and neuropsychology and joining NIH. she se rved as an associate the past 9 years. he was director of Division head of NIA ·s Oflice of Alzheimer's professor in the department or radiology in ur Research Grants. Priur lU bccu111i11g Lite Di:.ca:.e Re~earc h. has retired after 18 year~ the division or nucle:1r magnetic resonance DRG director. he spent 3 I years with the or government service. Once rcLirecl. he research al Johns I lopkins University National I-lean. Lung. and Blood Institute. plans to remain active in the fight against School or Medicine ... Or. Terrie W elle. a where he occupied several positions. H is Alzheimer\ disease. He will be working gcron1ologis1 who most rece ntly was direc re tirement plans include travel and time to with a former N IA colleague. NINR's Dr. tor of Lhc Brncelancl Ce nter ror Mental study history and archeology ... Dr• .Jan1 es Theresa Radebaugh. in a new consultancy Hea lth and Aging in Co11 nec1icu1. was C. Hill, N IA ID institute depu ty director called Khachalllrian Radebaugh Associates. named deputy director or the National since 1987. has retired after 20 yea rs al Inc., based in Potomac. Md .... Robert N. Institute on Aging ... Dr. Scott Whitcu11, N I H. He looks forward 10 travel ... Shirley " K nick" Knickerbocker . administra tive NEI associate cl inical direc tor since H opkins, who worked in the Office of officer for the N INOS Division of October 1993. has recen tly been named Human Resource Management in NII-l's Intramural Resea rch. has re1ired after 38 clinica l direc1or. As NEI clinical director. Division of Career Resources, fondly )'Cars of government service. His retire he is responsible ror the in1ra11111ral clinical known as the "recruitmem lady.'' has retired ment plans include traveling. learning oil research program and has established a sec after 25 years of government service ... Dr. painting. !>ailing and golling. He also will tion 10 provide resources for the design and A rthur Hoversland, scientilic review If) to work pan-time and volunteer ... Dr. conduct of intramural clinical tritLls ... D r . administrator of the human embryology and Kcit h L. Kraner. scientific review admin Jack Yano\!ski, an N ICI ID pediatric development study section. Referral and istrator of the surgery. anesthesiology. and endocrinologist since I 989, has been named Review Branch. DRG. has retired after I 7 trauma study ::.ection. Referral and Review chief of I I East. the Clinical Center·:. lirs1 years. In retirement. he will continue 10 live Branch. DRG. has retired after 28 years or muhi-instituh.! unit designed and staffed in the Frederick area and has plans 10 travel. active duty in 1hc uniformed services. His especially for children. including visits with his children in Indiana. future planli include writing a boo!... restor Oregon. and Hawaii .... Dr. Mor ris .J ones, ing a vintage car and fam1house. and travel head of the Special Foreign Currency ing ... Or . C harles Lowe. associate director RETIREMENTS Program at the Fogarty l111erna1ional for special projects at N ICHD. retired after Center. and a champion of international sci 27 years or government service. Although .J. Harr ison Ager , NIODK minority rro entilic cooperation, retired after more than he brought his expertise to a number of fed gram specialist. retired after 42 years or four decades of service to the U.S. govern era l and private institutions through his government service. 3X wi1h N II I. By train ment. The past 30 of Lhese yea rs were spent career. he both began and ended his service ing. he is a resea rch scientist 11nd came 10 at FIC and its predecessor. the Office or with N ICI ID. In re1ireme111. he will divide NIH in 1956 to work in the Laboratory or lmern<1lional Relations, N IH ... Richard .J . his 1ime between Woods Hole and Chemistry, bu t he gave up bench work in Kagan, health physicis1 with N II-l 's Office Camhriclgc. Mass .. pursuing his many inter 1973 1(1 become N IDDK 's firs1 EEO coordi or Research Services, retired 011 June 30. ests in public issues. as wel l as enjoying his nator ... Dr. Benjamin Burton, NIDDK One thing he will 1101 miss is an hour and hobbies ... Constance A. M atthews. 11 com associate uircctor for disease prevention and half' commute from the Ferndale. Md. area puter specialist for NCI 's Research technology transfer, has been named NIH (near Baltimore) that he has been doing Analysis and Evaluation Branch. part of the sc ientist emeritus after re1iring. During his since 1966. I-le is looking forward 10 travel Division of Extramural Activities. re1ired 34-ycar career. he helped develop protein ing with his wife ... Dr. Anthun.v R. Kalica J\pr. 14 after 3 1 yea rs or service. For three supplemen ts 10 fight m:ilnutrition in devel h a~ retired from lH after :i 3 I -year career decade),. she analyzed and indexed NCJ's oping countries. and helped develop new that spanned 1wo institutes and many scien scientilic grants. tracked the published technology for kidney dialysis. His text tific interests. Most recently he served as results through literature searches. main book. ll11111an Nutrition. now in it:. 4th edi senior scicntilic advisor in N HLBI 's tained 1he office's GENI US computer pro tion. has been translated into Spanish, Division of Lung Diseases. He started his grams and llow charts. corrected computer Ponugucse. and Arabic. At 75. he plans a career al IH and while working here malfunctions. and designed modilications 10 fifth edition of his tex1 and will continue his earned his Ph.D. His plans after retirement make the computer run smootl1er. Once research ... Dr. George .I. Cosmides, include continuing his profc:.sional inter retired. she is looking forward 10 spending deputy chief of NLM's Specialized ests. spending more time with his family. more time with her children. her church and Information Services. ha:. retired. He plans and enjoying such hobbies as running. gar l-Wimming ... Dr. Donald Murph ~• , direc to continue 10 pursue scholarly interests and dening and traveling ... Dr. Mel vin Kelchel tor of the Orlicc of Extramural Research's his passion for writing ... D r. Monique or the Referral and Review Brunch. DRG. Ex1r:1111ura l Starr Training Office. has Oubois- Oalcci, chief of NINOS' Laboratory has retired after 13 years of federal service. retired after a 28-ycar N il I career ... ol' Viral nnd Molecular Pathogenesis, Since 198 1. he was scientific review admin M ar ian Par k. an NINOS grants manage recent ly retired al'tcr 22 yea rs in the NII I istrator of a special study section 1ha1 mem officer. recently retired. ending a 35- community. Upon leaving her N INOS post. reviewed rehabili1ation and vision Smal l year career ol' dedicated service to NIH ... 27 N I H A A U P D A T E Ur. Richard J. Podolsky, a muscle biolo· become chief of the Laboratory of Cell ular scientist administrator until he retired in gist who served as chief of the Laboratory Physiology in the hean institute. During the 1968. died Apr. 6 in Tallahassee. Fla .... of Physical Biology at NIH for 20 years. I 95o·s and I 960·s. his work -pan of the Carolyn 8. Casper, 82. died of respiratory has retired. He was appointed scientist explosive growth of biomedical research failure July 27 at George Washington emeritus upon his retirement and he will and scient ific accomplishments-was Hospital. She lived in Washington. From continue his research ... Dr. Wilfred Rall, capped by his sharing of the Nobel prize. 1960 to 1975 she was tl1e director of Nlffs senior research physicist. Mathematical He influenced NIH on many other fronts: he Ofli ce of Management Policy .... Or. .J ohn Research Brnnch, NIDDK. has retired after help create the Foundation for Advanced W. Diggs, 59. fonner J}I deputy director 37 years of service with NIH and more than Education in the Sciences. he supponed for extramurnl research. died of colon can 40 years of research on the theoretical foun international scientists. and he involved cer, at his home on May 15. During his 20- dation of dendrit ic fu nction in neurons. hi mself in polit ical issues and human rights year NlH career he also held posit ions in Rall will continue his research as scientist activism ... Or. A.L. Loomis Bell, Jr., 72. NIAID and NINCDS. In 1993. nfter nearl y emeritus ... Or. Gerassimos Roussos, a who developed new diagnostic methods 35 years of federal service. Diggs left NlH health scientist administrator at the National during his 46 years as a heart and lung spe to become vice president for biomedical Institute of Dental Research. retired recently cialist at St. Luke·s Hospital in ew York, research at the Association of American after 32 years of federal service. His gov died from pulmonary fibrosis Apr. 25 at his Medical Colleges in Washington. D.C .. ernment career included 21 years at NIH. 12 home in Birdsboro, Pa. He was a postdoc where he was responsible for the develop of which were with NI DR ... .John Small, a toral fellow at the National Heart Institute ment of research and administrative policy public health advisor in NIDR's Disease in the USPHS in the early 1950's ... Dr. for the nation·s medical schools and teach Prevention and Health Promotion Branch. Orvil E.A. Bolduan, 78. who retired in ing hospitals ... Celia Carnine Dorn. 9 1. a has retired after 47 •/1 years of federal ser 1984 as executive secretary of the visual retired NIH employee who lived in the vice. almost 30 of them with the U.S. Public sciences study section of NII-r s research Washington area from 1932 to 1982. died of Health Service. Most of his PHS career grants division. died of a hean ailment Apr. pneumonia Apr. I 7 at a nursing home in focused on fl uoride. He has all sons of 7 at Suburban Hospital. Bolduan. who had Concord. Mass. She worked for NII-I , retirement plans includ ing one project. a doctorate in physical chemistry from where she did library services clerical work already under way. to work with the pla11 - Stanford Un iversity. also worked for U1e for about a clccade. before retiring in 1966. ning board for an aviation technology muse National Eye Institute before becoming Her husband. Dr. Harold Dom. a longtime um in College Park. He will also have more executive secretary of the visual sciences NCI scientist and statistician. died in 1963 time to devote to his fmnily. his antique car. study section in 1973 ... Or. Robert W. ... Dr. C harmian Elkes, 75. a psychiatrist travel. and his hobbies, especially photogra Bowman, 79. who retired in 1989 as chief who conducted early drug studies. died of a phy and dancing ... Eileen Smith, secretary of the Technical Development Laboratory heart attack Mar. 19 at Suburban Hospital. in the O ffice of Policy for Extramural at the National Hean. Lung and Blood In 1957. she moved to the Washington area Research Administration. Grants Policy Institute. died of pneumonia Feb. 27 at from England. where she joined the Office.OD. retired after 26 years of service. Suburban Hospital. A scientist at NIH since ational Institute of Mental Health. In Her retirement plans includ ing painting 1950. he became chief of the Laboratory of 1963, she joined the medical raculty at (oils and wutercolors), travel. and family. Technical Development in 1956. He devel Johns Hopkins as an associate professor of oped the Aminco-Bowman spectrophorol1u psychiatry. Beginning at NIMH and later at orometer. For that invention. he received Johns Hopkins. she played a major role in DEATHS the American Chemical Society award ia starting programs to train ment:1I health chemical instrumentation and the meritori counselors ... Godfrey Frankel, 82. a social William Oliver Allen, 75. a retired grants ous service and the distinguished service worker who was a program director for the management official. died May 27 ath is awards of the Public Health Service ... National Institute on Drug Abuse for 20 home in Bethesda following a heart attack. George Henry Brockelbank, 9 1. a certi years. died of congestive heart fa ilure July Arter retiring from the Navy in 1960. he fi ed public account:mt and lawyer who 11 at George Washi ngton University joined NIH where he worked until retiring retired from the office of management sur Hospital. He had a lifelong interest in pho in 1984 ... Or. C hristian B. Anfinsen, 79. vey and review at NIH in 1973. died May tography and after his retirement in 1982 died suddenly on May 14. He was profes 27 at Montgomery General Hospital. He began to exhibit his photographs of sor of biophysical chemistry at the Johns had joined NIH in the mid- 1960's ... Washington scenes. He received critical Hopkins University, a position he had Frederick S. Buschmeyer, Jr., 69, :1ssis acclaim and this fa ll. the Smithsoni an assumed after his reti rement from NIH in rnnt chief of the Audiovisu:1I Program Institution Press will publish a book of his 198 1. In 1972. he shared with Stanford Development Branen of the National photographs. "In The Alleys: Kids in the Moore and William H. Stein of Rockefeller Library of Medicine. died of cancer Apr. 11 Shadow of the Capitol'' ... Dr. Da\'id M. University the Nobel Prize for Chemistry. at his home in Washington. He transferred Fried. 86. who retired from Iii in 1974. He had been cited by the Swedish Royal to NIH in 1970 from the U.S. lnfom1ation died in February 1995 of a brain tumor in Academy of Sciences for his "studies in Agency where he had worked as a TV pro Majorca, Spain. He was chief of the ribonuclease. in parti cular the relationship duction chief and infomiati on officer ... Dr. Rehabilitation Department in the Clinical between the amino acid sequence and the .Jerry W. Carter, Jr. who served as chief Center from 1953 to 1974 ... Dr. George G. biologically active confomiation." He had clinical psychologist at NIMl-I from 1948 to Glenncr, 67. died July 12 at his home in first come to NIH in 1950 from llarvard to 1962 and then as program and personnel San Diego of complications from systemic 28 SUMMER 1 g g 5 senile amyloiclosis, a di~ea~e Lhat he hacl 15 years as a grant administrntor with NIH, Robert Thaddeus Scanlon, 68, a pedia1ric researched. From 1968 to l980. he worked died of complications from bronchitis and allergist and clinical professor al George at NIH as chief of the section of experi men emphysema Mar. 7 at a hospital in Boca town Universi1y Medical School, died of tal pa1hology. NIDDK. After he lefl NIH. Raton. Fla. She moved 10 Delray Beach. lymphoma Feb. 23 at Georgetown Univer he was appointed :lllending physician and Fla. in 1980 ... Or. Ralph Meader, 90, a sity Hospital. After finishing Georgetown research p:11hologis1 at 1he Medical School medical research administraior and inves1i University Medical School in 1954. he stud of the University of California at San gator. died May 5 a1 Franklin Regional ied allergy and immunology at NTH ... Dr. Diego. He colllinued his research in10 the Hospital in Franklin. N.H. In 1948. Meader Matthew Suffness, 52. an NCI cancer 1her molecular s1 ructure of 1he protein amyloid became a research grams executive at the apy researcher. died of pneumonia June 14 and it s re lation to Alzheimer's disease ... National Cancer Jnstilute. He left in 1965 at Holy Cross Hospital. In Nove mber, he Margarcl Lillia n Harris, 94. a registered 10 become deputy direc1or of research had received a bone marrow transplant. He nurse al NIH in the mid- I 950's and 60's. administration and cxcc111ive secrcrnry of came to NCI in 1976 as head of the plan I died of cercbrovascular arterioscleros is July the Commjttee on Research al and ani mal products section. Jn I 98 1, he 3 1 at Kensington Gardens Nursing and Massachusetts General Hospilal. He retired became chief of the Na1ura l Products Branch Rehabililation Cen1er. ln tbe 1950's. she in 1976 ... Dr. Alton Meister, 72. a bio and in 1989 became natural products grants moved to Washington from Phjladelphia chemist who was at NIH from 1945 to program coordinator. He was involved in and joined NII-l's fnsti1ute of Arthritis and 1957, died on Apr. 6 at the Mecliplex reha the development of taxol and was 1he editor Metabolic Diseases ... Dr. Clifton Keck bilitation center in Stamford Ct.. of compli of and contribu1ed 10 the 1995 text Himmelsbach, 88. a retired physician in the cations from a s1roke. He began his "Taxol-Science and Applications" ... Rose U.S. Pu bl ic Heallh Service who was 1he research career al NIH in 1945 and in 1957 Tortorella, 77. a medical librarian at NIH founding director of the Addiction Research lef1 10 become chairman of 1he dcpanmen1 from 1956 10 1968, died of cancer May 9 at Cen1er in Lexington, Ky .. and later the asso of biochemistry at Cornell ... Dr. Meiha n a nursing home in Boynton Beach. Fla .... cia1e dircCIOr or the Clinical Cenle r, died of Nonoyam, 57. cofoundcr and president of Rolf Versteeg, 59. a retired NIH program respiratory failure Mar. 20 at Sibley 1he Tampa Bay Research Institute in St. analyst. died May I :11 Holy Cross Hospiial Memorial Hospital. After a long career in Petersburg, died Mar. 24 of cancer al his afler a heart at1ack. Af1er he re1ired from 1he Public Health Service, be became in home. His research in molecular biology the Air Force in 1961, he joined NlH and 1955 the associate director of the Clinical and viral oncology was supported by grants retired as a program analyst in 1992 ... Center until he retired in 1965. Following from NlH. He also served on various NIH Hania M. Warfield, 89. a former scientific his rcti remc111 he taught from 1965 10 1977 and NCI boards. He was especially known Lrw1slator for NII-I . died Mar. 16 at al Georgetown University Medical School for his original studies of 1he Epstein-Barr Rockville Nu rsing Home of complicalions where he was forn1er associa1e clean and virus ... .John James Norlon, 80. a reti red related to a stroke suffered in 1990. She professor cmeri1us of pharn1acology ... NIH employee. died in his Rockville home was a scientific 1ranslator at NrH from 1949 John Jackson, 68, a labora1ory 1echnician on Mar. 2. He worked at NIH in planning until 1954 and again in the la1e I 950's and who retired from NIH in 1992, died of can and con1Tol in the Division of Researc h early I 960's ... Elsie Irene Weide, 84, a cer June 27 al his home in Mitchell ville. He Services before retiring in 1974 ... Marie secretary who retired in 1974 from NJMH joined NIH in the early 1960's and worked O 'Neil, 64, died Jul ~· 19 of cancer at her after I 0 years of service, died of pneumonia !here 29 years before re tiring ... Isabel home in Bethesda. A secretary in 1he July 30 at 29 N I H A A U P D A T E NIH Retrospectives mals (see phoro below) ... According to of this institution which is testimony to a recent survey. the typical Federal its greatness as a training ground for career employee retiring in 1964 after leaders in health and in medicine.. ·- age 60 w ith at leas t 30 years service On Aug. 1. Dr. Dorland J. Davis retired was male. married. 65 years old. and as Nl A rD director. a position he had entitled to an annuity of $402 a month held since I 964. His retiremeni com based on an average of about 38 years pleted a 36-year PHS career marked by of Federal service. scientific achievements and administra tive innovari ons. Summer 1955 By a departmental order dated June 8. 1955. DHEW Secretary Ovew Culp Hobby created a new organization at • .0.11~,.:. TheNIH Record NIH-the Division of Biologics -....··-- -- - Standards. Established to reflect the - expanded NIH program in biologics Summer 1975 control. the Division replaces the for Summer 1985 mer National Microbiol()gical President Gerald R. Ford and HEW Institute ·s Laboratory of Biologics Secretary Caspar W. Weinberger par The Howard Hughes Medical Control. The new program has divi ticipated in ceremonies held at N I 1-1 on Institute and the National lnstitute or sional status (comparable orgm1ization Ju ly I to administer the oath of ofiice Health have chosen 25 medical Slll al ly ro an institute) and thus w ill be to Dr. Theodore Cooper. the new HEW dents who will panicipate in the first responsible to th e N IH direc tor. Dr. assistant secretary for heallh. and Dr. year of the HHMl-NIH Research Carl L. Larson. direc1or or the NMI Donald S. Fredrickson. the new NIH Scholars Program ... American and Rocky M ountain Laboratory, in director. At the ceremony. President Japanese scientists met July 18 and 19 Ham ilton, Mon1., has been named chief Forti noted that in ··honoring the two 10 celebrate 20 years or internmional or th e Division and will be responsible men who are raking office today. we biomedical cooperation begun with the for planning and organizing 1he new are paying a long-deserved tribute to U.S.-Japan Cooperative Medical program. NIH because both or them are products Science Program. On May 26, 1995, Dr. Helen M. Dyer celebrated her 100th birthday. She is shown here in a photo taken by Dr. Mairin Brennan, senior editor at Su mmer 1965 Chemical & Engineering News. Dyer who received Dr. Helen M. Dyer of 1he Nutrition the 1962 Garvan Medal for and Carcinogenesis Section in NCl"s her pioneering research in Laboratory of Biochemis1ry. retired biochemistry, is still May 31. She Carne to NCI as a active, reports Brennan. Dyer " ... reads C&EN, fol research fellow. recruited by Dr. Carl lows the DNA evidence Voegtlin, the first NCI director. Her being presented at the O.J. research focused on the metabolism or Simpson trial, and is learn rhe carcinogen lluorenylacetamide and ing all about e-mail." chemically related compounds in ani- Photo courtesy of Chemical & Engineering News. 30 SUMMER 1 9 9 5 NIH HISTORICAL OFFICE DEWITT STETTEN, JR. MUSEUM OF MEDICAL RESEARCH OFFICE OF COMMUNICATIONS SELECTED REFERENCES ON NIH HISTORY Harden. Victoria A .. Inventing 1he NIH: Federal Bio111edical Research Policy. 1887- 1937. Baltimore: Johns Hopkins Un iversity Press. 1986. Focuses especially on transition rrom private Lo federal support for research between World War I and 1930. Mider, G. Burroughs, ·'The Federal lmpacr on Biomed.ical Research," in John Z. Bowers and Elizaberh F. Purcell. eds., Advances i11 American Medicine: Essays a11/Je Bicewe1111ial, 2 vols. (New York: Josiah Macy, Jr., Foundation, 1976) 2: 806-7 1. Especially good on post-World Warll period. Mullan, Fitzhugh. Plag 11es and Polilics: T/le S1ory of 1/Je United Stares Public Heal1/J Sen•ice. New York: Basic Book:.>, 1989. Photo essay prepared ror the centennial or the PHS Commissioned Corps. Shorter, Edward, The Heal!h Century. New York: Doubleday. l987. Popular account of med ical research written as a companion to the PBS series by the same title. Steuen, DeWiu , Jr. and William T. Carrigan, eds. NIH: A11 Acco11111 of Research in /1s Laboratories and Clinics. Orlando, Fla.: Academic Press, 1984. Chapters by leading intramural NJH investigators about their work. Stri.ckland, Stephen P .. Politics. Science. cmd Dread Disease: A Short History of United Stmes Medirnl Research Policy. Cambridge: Harvard University Press. 1972. Covers emergence of modern NIH after World War fI. Strickland, Stephen P., The Story of the NIH Grams Program. Lanham, Md.: Uni versity Press of Ameri ca. 1989. Based largely on oral histori es with key fi gures who shaped the grants progntm. For a copy of the NIH Historical Office's ;u111otated bibliography of selected NIH history references. wri1 e to Dr. Victoria A. Harden. NIH historian. at Bldg. 3 1. Room 2809. NTH. Bethesda. MD 20892-2092: (30 I) 496-66 I 0. The bibliograp hy is also avaiJable to be downloaded from the NIH informati on Center computer bu lletin board. To access it, set you communications parameters for: 8 databits. I stop bit. and no parity: ter mi nal emulation to ANSI; highest speed supported is 14.400 bps. The local number in Bethesda. MD. is (30 1) 480-5 144. If you live outside the local calling area, dial 1-(800) NrH-BBS I (644-227 1) . These architect's drawings of the proposed Bldgs. 3, 1, and 2 for the new NIH campus in Bethesda, appeared in the Washington Star, Aug. 26, 1937 31