Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_001431405Cyc: Pseudoxanthomonas dokdonensis DSM 21858 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari

lipid II (meso diaminopimelate molybdate containing) putrescine ammonium phosphate spermidine

ModC FtsW PotA RS08900 RS02430 MgtE FtsE SecG RS05420 RS06870 RS09970 RS04725 RS08315 CorA RS08215 RS01625 RS13675 FliF FliN RS11545 FlhF RS06485 MreD RS13365 RS09305 GltS RS09200 TatC TatA RS03945 LptG RS09330 Cls RS14980 RS13465 FlhA RS12200 RS04390 RS00535 TolR RS09715 RS04570 RS09765 RS09805 SecD RS04950 CcmD RS13940 RS02110 UbiB PstC RS00880 RS09005 PstB

lipid II (meso diaminopimelate putrescine molybdate ammonium containing) spermidine phosphate

RS01265 FlgL Cofactor, Carrier, and Vitamin Biosynthesis Hormone Biosynthesis Inorganic Nutrient Metabolism Macromolecule Modification tRNA-uridine 2-thiolation Degradation/ ATP biosynthesis ditrans,octacis- a peptidoglycan with a methylated UDP-N-acetyl-α-D- L-alanyl-γ-D- a peptidoglycan β a [protein] and selenation (bacteria) Utilization/ ditrans,octacis- ditrans,octacis- UDP-N-acetyl- a nucleoside N- -aspartyl- an L-asparaginyl- biotin biosynthesis I indole-3-acetate selenate reduction assimilatory Assimilation - Other undecaprenyldiphospho- (L-alanyl-γ-D-glutamyl- 2-oxoglutarate nucleobase muramoyl-L-alanyl- undecaprenyldiphospho- undecaprenyldiphospho- glutamyl-meso- UDP-N-acetyl- a [glutamine- α-D-muramoyl- D-glt γ-L-glutamyl- gly dimer (meso- RNA C-terminal glu [2Fe-2S] iron-sulfur superpathway of tetrahydrofolate biosynthesis dipyrromethane ubiquinol-8 biosynthesis cytidylyl molybdenum superpathway of coenzyme A biosynthesis I (bacteria) superpathway of thiamine diphosphate biosynthesis II pyridoxal 5'-phosphate biosynthesis I menaquinol-9 biosynthesis Tetrapyrrole Biosynthesis thiosulfate oxidation III (multienzyme complex) nitrate reduction V (assimilatory) ATP triphosphate L-arginine dGDP [tRNA Asn ] FlgJ FlgK N-acetyl-(N-acetyl-β-D- L-lysyl-D-alanyl-D- within DNA γ-D-glutamyl-meso- diaminopimelate α-D-muramate synthetase]- D-alanine diaminopimelate L-glutamate cluster biosynthesis cofactor biosynthesis (late decarboxylation) cofactor sulfurylation biosynthesis sulfate reduction IV acrylonitrile D-alanyl-D-alanine N-acetyl-(N- N-acetyl-(N- L-alanine cys ADP glucosaminyl)muramoyl- alanine) pentapeptide 2,6-diaminopimelate L-tyrosine containing) ribonucleotide- a malonyl-[acp] 3-methyl-2- a 5,10- D-erythrose superpathway of heme b IV (bacteria) selenate degradation I acetylglucosaminyl) acetylglucosaminyl) an apo-[hydroxymethylbilane cytidylyl molybdenum a [ThiS sulfur- demethylmenaquinol-9 siroheme biosynthesis (indol-3-yl) sulfate a [SoxY protein]-L-cysteine sulfate nitrate L-alanyl-γ-D-glutamyl-L- alpha-ketoglutarate- γ isoaspartyl diphosphate malonyl-ACP O- L-cysteine desulfurase GTP chorismate oxobutanoate methylenetetrahydrofolate 4-phosphate biosynthesis from glutamate cysteine F0F1 ATP synthase: muramoyl-L-alanyl- - muramoyl-L-alanyl- UDP-N- UDP-N- glutathione DNA- 30S aminoacyl- synthase]-L-cysteine cofactor (trioxo) cys carrier protein] bifunctional acetonitrile adenylyltransferase: sulfate lysyl-D-alanyl-D-alanine dependent β γ peptidase/L- reductase: methyltransferase D-erythrose- desulfurase: ABB29_RS02470 atpD acrylonitrile UDP-N- D-isoglutaminyl-N-( - -D-isoglutaminyl- acetylmuramate:L- bifunctional [glutamate- acetylmuramoyl- synthetase: penicillin- directed RNA ribosomal tRNA demethylmenaquinone adenylyltransferase: dioxygenase AlkB: β asparaginase: ABB29_RS13165 RS04085 FliD BioC: bioC cysteine 3-methyl-2-oxobutanoate 4-phosphate uroporphyrinogen-III atpG ABB29_RS02485 cysD cysN acetylmuramoyl- D-asparaginyl)-L-lysyl- N-( -D-asparaginyl) alanyl-gamma-D- -ammonia ligase]- L-alanine--D- ABB29_RS05315 binding polymerase protein hydrolase: a malonyl-[acp] GTP an [MCD cofactor cysteine methyltransferase/2- glu ABB29_RS14575 adenosine 5'- cysD cysN ABB29_RS14330 ABB29_RS05830 ABB29_RS13175 desulfurase: a [hydroxymethylbilane hydroxymethyltransferase: dehydrogenase: uroporphyrinogen-III (indol-3-yl) an [L-cysteine ABB29_RS02490 monofunctional tripeptide--D-alanyl- D-alanyl-D-alanine -L-lysyl-D-alanine glutamyl- meso- adenylyl-L-tyrosine glutamate ligase: protein subunit S6--L- pth methyl ester cyclohydrolase 4-hydroxybenzoate chaperone]-MCD desulfurase: methoxy-6-polyprenyl- glutamate- phosphoselenate APS glutathione ABB29_RS14575 synthase] ES intermediate panB gap C-methyltransferase: acetamide desulfurase]-S- ABB29_RS02495 atpE a [SoxY protein]-S- nitrite biosynthetic alpha-ketoglutarate- D- alanine ligase: diaminopimelate phosphorylase/ ABB29_RS14660 2: mrdA omega: rpoZ isoaspartyl adenosylcobalamin- glutamate I FolE2: 2 a carboxy- 1,4-benzoquinol -tRNA acrylamide synthase: aminoacyl- beta-ketoacyl- 4-hydroxybenzoate cysteine ABB29_RS14575 atpB ABB29_RS02510 sulfosulfanyl-L-cysteine dependent [glutamate-- peptidase/L- dependent an S-sulfanyl-[L- ABB29_RS03565 hydroxymethylbilane asp an [L-cysteine adenylated- 4-phospho- methylase UbiE: ubiE ligase: gltX ABB29_RS00500 amidase: sulfanyl-L-cysteine peptidoglycan ABB29_RS06780 monofunctional monofunctional ligase: mpl gshB [+ 4 isozymes] ligase: rimK tRNA ACP synthase octaprenyltransferase: desulfurase: D-glyceraldehyde an L-glutamyl- ATP adenylyl-sulfate dioxygenase AlkB: ammonia-ligase] asparaginase: ribonucleoside- cysteine desulfurase] synthase: hemC desulfurase]-S- [ThiS sulfur- D-erythronate menaquinol-9 [+ 2 isozymes] ABB29_RS13950 amidase: transglycosylase: biosynthetic biosynthetic UDP-N-acetyl- a peptidoglycan hydrolase: FlgA RS04495 GTP ABB29_RS14575 2-dehydropantoate 3-phosphate [tRNA Glu ] cytochrome c: kinase: cysN adenylyltransferase: ABB29_RS00145 diphosphate II: fabF ubiA aspartate 1- precorrin-1 ABB29_RS13950 mtgA ABB29_RS09180 UDP-N-acetyl-α-D- peptidoglycan peptidoglycan UDP-N-acetyl- α-D-muramoyl-L- with D,D cross- D-ala arfB cyclohydrolase a [hydroxymethylbilane a [cytidylyl molybdenum sulfanyl-L-cysteine carrier protein] selenite ABB29_RS10145 glnE RNA reductase: a [protein] C- a 3-oxoglutaryl- 4-hydroxy-3- decarboxylase: 1-deoxy-D- glutamyl-tRNA (indol-3-yl)acetate PAPS muramoyl-L-alanyl- transglycosylase: transglycosylase: α-D-muramoyl- alanyl-D-glutamate norophthalmate links (meso- α I FolE: folE synthase] ES intermediate cofactor chaperone]- uroporphyrinogen-III a [TusA sulfur- cytochrome c: ammonium ABB29_RS01930 terminal -L- 3 octaprenylbenzoate ABB29_RS10730 xylulose-5- acrylate a nucleobase γ γ [acp] methyl ester 7,8- cysteine gly reductase: carrier protein]-S- a peptidoglycan with di-trans,octa-cis formaldehyde succinate -D-glutamyl-meso- mtgA mtgA L-alanyl- -D- diaminopimelate glutamate-α- hydroxymethylbilane cytidylyl molybdenum phosphate (3R)-3-hydroxy-2-oxo- C-methyltransferase: ABB29_RS04650 phosphoadenylyl- within DNA arg asp GDP 3-oxoacyl- an S-sulfanyl-[cysteine dihydroneopterin 4-hydroxy-3- desulfurase: ABB29_RS15715 sulfanyl-L-cysteine (L-alanyl-γ-D-glutamyl- -undecaprenyl 2,6-diaminopimeloyl- glutamyl-meso-2,6- a [glutamine containing) L-glutamate asn tRNA Asn RS14960 RS04500 synthase: hemC cofactor (sulfo-dioxo) β-alanine synthase: 4 phosphooxybutanoate ABB29_RS00500 sulfate reductase: ACP desulfurase]-[disordered- 3'-triphosphate octaprenylbenzoate (R)-pantoate ABB29_RS14575 menaquinol-8 biosynthesis (S)-4-amino-5- a [SoxY protein]-S- a [SoxY protein]-S glutamine glutamate L-lysyl-D-alanyl-D- diphosphate D-alanyl-D-alanine a peptidoglycan di-trans,octa-cis a peptidoglycan di-trans,octa-cis diaminopimelate synthetase]-O dxs phosphoserine uroporphyrinogen-III ABB29_RS07610 4 form scaffold a [hydroxymethylbilane 5-hydroxylase: D-glyceraldehyde oxopentanoate selenodiglutathione disulfanyl-L-cysteine -sulfanyl-L-cysteine synthetase: synthase alanine) pentapeptide dimer (E. faeciums) -undecaprenyl dimer (E. faecium -undecaprenyl -(5'-adenylyl) reductase a thiocarboxylated- transaminase: pyruvate C-methyltransferase: protein] complex synthase] ES intermediate ABB29_RS03010 1-deoxy-D- 3-phosphate ABB29_RS08350 large diphosphate , tetrapeptide) diphosphate -L-tyrosine FabG: fabG 4 pantoate--beta- serC demethylmenaquinol-8 glutamate-1- a [TusD sulfur- sulfite 3,4-dihydroxy- xylulose 5- [ThiS sulfur- 2-iminoacetate cobA subunit: gltB 3-oxoacyl- 7,8- hydroxymethylbilane alanine ligase: bifunctional semialdehyde carrier protein]-S- [+ 2 isozymes] YbgF RS14370 5-all-trans- phosphate carrier protein] 4-phosphooxy- 1-deoxy-D- ACP dihydroneopterin synthase: hemC ABB29_RS10735 demethylmenaquinone 2,1- precorrin-2 sulfanyl-L-cysteine di-trans,octa-cis UDP-N-acetyl- a mature peptidoglycan a [bis(guanylyl a [glutamine DNA with adenine:7,8- L-alanyl-γ-D- octaprenylbenzoate AIR L-threonine + a [DNA]-3'- a 5'-phospho- ditrans,octacis- phosphoenol a [protein]-L- a [cysteine desulfurase]- xylulose-5- menadione NADH H NAD + MoO - 34 an L-cysteinyl- F0F1 ATP 3'-phosphate aminomutase: glutathioselenol -undecaprenyl α molybdopterin) synthetase]-O dihydro-8- 2 β glutamyl-L-lysyl- a cytidine lys + + reductase thiazole synthase: methyltransferase/2- -D-muramoyl- (meso-diaminopimelate hydroxyl [DNA] undecaprenyldiphospho- cys -isoaspartate Cys H H a holo-[hydroxymethylbilane 4-hydroxythreonine- phosphate gln glu ATP dGDP pyruvate dADP Ile2 [tRNA ] synthase FabG: fabG S-sulfanyl-[disordered- ABB29_RS07705 methoxy-6-polyprenyl- hemL siroheme synthase: phosphatephospho-N- L-alanyl-γ-D- containing) cofactor 4 -(5'-adenylyl) oxoguanine mismatch molybdopterin protein-L- D-alanyl-D-alanine in tRNA synthase] (R)-pantothenate phosphomethylpyrimidine 4-phosphate synthase: hydrogen sulfide N-acetyl-(N- a (3R)-3- form scaffold 1,4-benzoquinol ABB29_RS01790 a [SoxY protein]-S-(2- acetylmuramoyl- glutamyl-meso-2,6- chaperone]- -L-tyrosine cofactor isoaspartate O- ribonucleotide- 3-methoxy-4- synthase ThiC: thiC dehydrogenase dxs 5-aminolevulinate a [TusE sulfur acetylglucosaminyl) TolB RS08665 hydroxyglutaryl- protein] complex 2-[(2R,5Z)- urea cycle sulfodisulfanyl)-L-cysteine pentapeptide- NADH-quinone DNA γ L-cysteine methyltransferase: diphosphate type III methylase UbiE: ubiE 34 carrier protein]-S diaminopimeloyl- muramoyl-L-alanyl- -D- A/G-specific penicillin- tRNA cysteine D-erythro-7,8- hydroxy-5-all-trans 2-carboxy-4- PdxA: pdxA sirohydrochlorin a uridine in tRNA transferase: lytic murein oxidoreductase: nuoN ligase reductase: aminoacyl- NAD(P) [acp] methyl ester pantothenate HMP-P 3-amino-1- menaquinol-8 -sulfanylcysteine D-alanyl-D-alanine transglycosylase: isoglutaminyl-L-lysyl- adenine molybdenum cofactor pyruvate ABB29_RS12515 binding lysidine(34) tRNA H + H + 3-hydroxyacyl- desulfurase: dihydroneopterin chorismate -octaprenylbenzoate methylthiazol-5(2H 1-deoxy-D- porphobilinogen hydrogen selenide ABB29_RS06785 ABB29_RS10430 nuoK D: ligD bifunctional [glutamate- ABB29_RS13165 transhydrogenase kinase: hydroxyacetone assimilatory ABB29_RS12650 (glycyl) -D-alanyl-D-alanine glycosylase: guanylyltransferase: kinase: pyk protein-L- protein synthetase hydrolase: ACP ABB29_RS14575 dihydroneopterin bifunctional )-ylidene]ethyl xylulose 5- synthase: hemB siroheme synthase: arg ABB29_RS10445 nuoI 5 cysteine -ammonia ligase]- ABB29_RS13175 an S-sulfanyl-[cysteine aminodeoxychorismate ABB29_RS08755 1-phosphate tRNA 2- polyphosphate metabolism sulfate reduction III NAD- mutY ABB29_RS01780 isoaspartate(D- 2: mrdA TilS: tilS pth dehydratase aldolase: folB hydroxymethylpyrimidine phosphate phosphate ABB29_RS01790 [+ 2 isozymes] nuoH nuoG nuoF nuoE desulfurase: adenylyl-L-tyrosine RS08330 desulfurase]-S- synthase component (R)-4'- porphobilinogen thiouridine(34) dependent aspartate) O- adenosylcobalamin- FabZ: fabZ kinase/ ABB29_RS10475 monofunctional ABB29_RS14575 phosphorylase/ aminoacyl- sulfanyl-[disordered- 6-(hydroxymethyl) I: ABB29_RS03170 2-methoxy-6-(all-trans phosphopantothenate pyridoxine 5'- siroheme synthase ammonium sulfate DNA ligase adenylyl methyltransferase: L-alanyl-γ-D- dependent phosphomethylpyrimidine argininosuccinate long chain a mature peptidoglycan a mature peptidoglycan ABB29_RS10480 biosynthetic [glutamate-- an apurinic site pyruvate a lysidine 34 tRNA RS12355 a (2E)-enoylglutaryl- form scaffold -7,8-dihydropterin -octaprenyl)phenol phosphate hydroxymethylbilane MnmA: mnmA arginase: sulfate LigA: ligA molybdenum dGTP ABB29_RS15175 glutamyl-L- ribonucleoside- aminodeoxychorismate/ bifunctional kinase: thiD lyase: argH polyphosphate undecaprenyldiphospho- UMP with (L-alanyl-γ-D- strand (non- peptidoglycan a [bis(guanylyl ammonia-ligase] within DNA a protein L-β- D-ala in tRNA Ile2 hydrolase: [acp] methyl ester protein] complex 2-(2-carboxy-4- synthase: hemC rocF glutamine- adenylyltransferase: adenine cofactor diphosphate 2-amino-4-hydroxy-6- anthranilate synthase 2-octaprenyl-6- phosphopantothenoylcysteine synthase: N-acetylmuramoyl-L- glutamyl-meso-2,6- reducing terminus) transglycosylase: ala molybdopterin) adenylyltransferase: isoaspartate lysyl-D-alanine arfB methylthiazol-5- a 2-thiouridine 34 hydrolyzing cysD cysN reductase: RS08335 methoxyphenyl ABB29_RS00855 γ + enoyl-ACP hydroxymethyldihydropteridine component II: decarboxylase/ HMP-PP carbamoyl- alanyl- -D-glutamyl-meso diaminopimeloyl-D- NAD menadiol [DNA] NMN mtgA cofactor glnE α-methyl ester hydroxylase: ubiH yl)ethyl phosphate preuroporphyrinogen in tRNA L-arginino- polyphosphate APS ABB29_RS01930 reductase: diphosphokinase: ABB29_RS08955 phosphopantothenate-- L-ornithine phosphate -2,6-diaminopimeloyl- alanine) tetrapeptide AMP chaperone]-S- 2-methoxy-6-all tRNA uridine-5- succinate kinase 2: ppk2 ADP ABB29_RS15060 a [cysteine ABB29_RS13740 4-amino-4- cysteine ligase CoaBC: coaBC pyridoxine uroporphyrinogen- synthase: exopolyphosphatase: ppx phosphoadenylyl- D-alanyl-D-alanine a peptidoglycan di-trans,octa-cis sulfanyl-L-cysteine a [glutamine- cys a tRNA Cys RS08985 trans-octaprenyl- thiamine carboxymethylaminomethyl(34) polyphosphate a glutaryl-[acp] desulfurase]-(S- 2-amino-4-hydroxy-6- deoxychorismate (R)-4'- 5'-phosphate III synthase: carA carB sulfate reductase: dimer (S. aureus) -undecaprenyl synthetase]- 1,4-benzoquinol phosphate synthesis enzyme MnmG: mnmG kinase 1: ppk1 ADP methyl ester sulfanyl) -[disordered- hydroxymethyldihydropteridine phosphopantothenoyl- pyridoxamine ABB29_RS00495 Secondary Metabolite Biosynthesis ABB29_RS07610 diphosphate L-tyrosine RS15920 2 bifunctional synthase: carbamoyl form scaffold diphosphokinase: folK L-cysteine superpathway of thiamine diphosphate biosynthesis I 5'-phosphate NAD salvage pathway II (PNC IV cycle) tRNA uridine-5- beta-ketoacyl- demethylmenaquinone ABB29_RS07165 uroporphyrinogen-III carboxymethylaminomethyl(34) phosphate sulfite protein] complex (7,8-dihydropterin- bifunctional oxidase: pdxH methylerythritol phosphate pathway I argininosuccinate ornithine ACP synthase methyltransferase/2- phosphopantothenoylcysteine preQ biosynthesis synthesis GTPase MnmE: mnmE synthase: carbamoyltransferase: long chain 6-yl)methyl + 0 γ II: fabF 4-aminobenzoate ubiquinol-8 biosynthesis methoxy-6-polyprenyl- cys NAD uroporphyrinogen polyphosphate assimilatory sulfite a ring-opened 7- a single L-alanyl- -D- a peptide with a [protein]- a 2,3,4-saturated phosphoenol a peptidoglycan queuosine at diphosphate decarboxylase/ thiamine PLP NAD(+) a 5-carboxymethylaminomethyl- ABB29_RS03625 ABB29_RS03620 methanethiol O-succinyl-L- a [ThiI sulfur-carrier an N-modified serotonin NADH MotD (early decarboxylation) 1,4-benzoquinol decarboxylase: D-glyceraldehyde reductase (NADPH): methylguanine stranded DNA cys glutamyl-meso-2,6- an N-terminal L-glutamine 1,2-diacyl-sn pyruvate dimer (E. faeciums) ala UDP-N-acetyl- glu position 34 LolA a 3-oxopimeloyl- flavin biosynthesis I (bacteria and plants) phosphopantothenate-- phosphate diphosphatase: pyruvate 34 L-citrulline homoserine protein]-L-cysteine aminoacyl-[tRNA] dADP ATP 3-phosphate 2-thiouridine in tRNA in DNA diaminopimeloyl- UDP-N-acetyl- Xaa-L-proline -glycerol 3- α of a tRNA Asp a [cysteine desulfurase]- dihydropteroate all-trans- methylase UbiE: ubiE cysteine NAD+ synthase: ABB29_RS08115 cysI ABB29_RS07620 -D-muramate biotin [acp] methyl ester 6-methoxy-3-methyl- cysteine ligase CoaBC: coaBC thiamine- nudC GTP D-alanine α-D-muramate phosphate CTP [scaffold protein- synthase: folP octaprenyl desulfurase: ABB29_RS06905 penicillin- NAD(+) 3-oxoacyl- 4-hydroxybenzoate 2-all-trans-octaprenyl- phosphate coproporphyrinogen III 1-deoxy-D- GTP cyclohydrolase I hydrogen sulfide exodeoxyribonuclease O-succinylhomoserine transglutaminase (2Fe-2S)] complex diphosphate 4'-phosphopantetheine ABB29_RS14575 NAD+ synthase: bifunctional DNA- cysteine leucyl aminoacyl- binding UDP-N- tRNA diphosphatase: ACP 1,4-benzoquinol GTP kinase: thiL an [L-cysteine xylulose-5- FolE2: ABB29_RS03565 VII large subunit: (thiol)-lyase: domain-containing 7,8- ABB29_RS06905 oxygen-dependent a 5-aminomethyl-2- formamidopyrimidine desulfurase: UDP-N- aminopeptidase: tRNA pyruvate protein acetylmuramate-- glutamyl- nudC bifunctional RS05015 reductase thiamine desulfurase]-S- a [ThiS sulfur- phosphate ABB29_RS03340 ABB29_RS08020 protein: RS00870 4-hydroxybenzoate pantetheine- nicotinate adenine coproporphyrinogen GTP cyclohydrolase 34 glycosylase/ ABB29_RS14575 acetylmuramate:L- ABB29_RS09255 hydrolase: kinase: pyk 2: mrdA L-alanine ligase: Q(34) biotin-- dihydropteroate GTP sulfanyl-L-cysteine carrier protein] NMN thiouridine in tRNA exodeoxyribonuclease ABB29_RS00405 FabG: fabG octaprenyltransferase: phosphate diphosphate dinucleotide synthase: dxs I FolE: folE Carboxylate Degradation DNA-(apurinic cystathionine ABB29_RS06800 [acetyl-CoA- a [co-chaperone]- bifunctional cyclohydrolase cysteine oxidase: hemF 7,8-dihydroneopterin 3'-triphosphate VII small subunit: alanyl-gamma-D- Xaa-Pro pth synthetase reduced β- 3-oxoacyl- ubiA adenylyltransferase: or apyrimidinic gamma-synthase: a [ThiI sulfur- glutamyl- meso- GluQRS: carboxylase] [scaffold protein- tetrahydrofolate II: ribB aminopeptidase: aminoacyl- 6 a peptidoglycan nicotinamide D- ACP 3-demethylubiquinol-8 coaD desulfurase: protoporphyrinogen IX 1-deoxy-D-xylulose 2-methylcitrate cycle I ABB29_RS11495 ABB29_RS09065 a [protein] N - a CDP-2,3,4- AMP ligase/biotin (2Fe-2S)] complex synthase/ 2,5-diamino-6- site) lyase: mutM ala carrier protein]-S- diaminopimelate pepP tRNA pyruvate tetramer with a D-ala UDP-N-acetyl- gluQRS ribonucleotide reductase NAD de novo biosynthesis ABB29_RS14575 5-phosphate 6-carboxytetrahydropterin a 5-methylaminomethyl- pyruvate decarboxylation to acetyl CoA I acrylate degradation II [(5-hydroxy-1H- saturated- operon RS01935 dihydrofolate 4-hydroxy-3- (5-phospho-D- 3'-dephospho- a [ThiI sulfur- a carboxy- nicotinate-nucleotide sulfanyl-L-cysteine ligase: mpl hydrolase: dATP D,D cross-link α-D-muramoyl- FabG: fabG bifunctional 2- ribosylamino) CoA II (from tryptophan) D-glyceraldehyde 1-deoxy-D-xylulose- synthase QueD: queD 2-thiouridine 34 in tRNA a single-stranded indol-3-yl)ethyl]- diacylglycerol repressor synthase: folC octaprenylbenzoate carrier protein]-S- adenylated-[ThiS adenylyltransferase: propanoate a [pyruvate dehydrogenase a [DNA]- a 5'-phospho- 2,6-diamino-4- a ribonucleoside succinate a peptide with arfB (Enterococcus L-alanine glutamyl- RS08775 a (3R)-3- polyprenyl-6- pyrimidin- AIR 3-phosphate 5-phosphate pyruvate coenzyme A acrylate 4-oxo-2-pentenal oligodeoxyribonucleotide met a proteinogenic L-glutamine BirA: birA dephospho- sulfanyl-L-cysteine sulfur-carrier protein] nadD 6-carboxy-5,6,7,8-tetrahydropterin E2 protein] N 6 -lipoyl-L-lysine pyruvate nucleotide- hydroxy-5-(N-methyl) 5'-monophosphate UDP-N-acetylmuramoyl- faecium) queuosine at hydroxypimeloyl- a [chaperone-ATP]- 7,8-dihydrofolate hydroxyphenol tyr reductoisomerase: dehydrogenase [DNA] an N-terminal 4(3H)-one CoA kinase: trp 1-deoxy-D- NaMN propionate- 3'-phosphate formamidopyrimidine L-alanyl-γ-D- amino acid position 34 [acp] methyl ester [co-chaperone]- monoglutamate methylase/3- phosphomethylpyrimidine protoporphyrin IX ABB29_RS11415 (acetyl-transferring) L-proline RS12990 bifunctional ABB29_RS06845 tryptophan 2,3- xylulose-5- 7-carboxy-7-deazaguanine -CoA an N-modified an uncharged Asp 3-hydroxyacyl- [scaffold protein- demethylubiquinol 3- synthase ThiC: thiC a 5-methylaminomethyl- dihydrolipoyl , homodimeric propionate- glutamyl-meso-2,6- of a tRNA biotinyl-5'- 2-octaprenylphenol diaminohydroxyphosphoribosylaminopyrimidine dioxygenase: phosphate synthase QueE: queE ligase: prpE amino acid tRNA ACP (2Fe-2S)] complex O-methyltransferase coenzyme A ferrochelatase: MEP 2-(S-geranyl) dehydrogenase: lpdA type: aceE -CoA diaminopimeloyl- adenylate deaminase/5-amino-6-(5-phosphoribosylamino) ABB29_RS08845 synthase: dxs 34 long-chain fatty dehydratase UbiG: ubiG N-Formyl-L- HMP-P a thiocarboxylated- adenosylcobinamide-GDP hemH thiouridine in tRNA ligase: prpE D-alanine uracil reductase RibD: ribD 1-deoxy-D-xylulose 7-carboxy-7-deazaguanine acid--CoA ligase: dihydrolipoyl pyruvate PstS FabZ: fabZ kynurenine 2-iminoacetate [ThiS sulfur- salvage from cobinamide I 2-C-methyl-D- a 7,8-dihydrofolate 5-amino-6-(5- 5-phosphate tetrahydrofolate salvage from protein S-nitrosylation ABB29_RS05180 dehydrogenase: lpdA dehydrogenase ubiquinol-8 bifunctional carrier protein] protoheme erythritol 4-phosphate a 7,8-dihydro- α a [protein]-L- RS12995 a (2E)-enoylpimeloyl- phospho-D- 5,10-methenyltetrahydrofolate 7-cyano-7-deazaguanine and denitrosylation (acetyl-transferring) acryloyl-CoA -Kdo-(2->4)- a carboxy- a DNA containing a mature a guanine 2445 3-(all-trans hydroxymethylpyrimidine cob(II)inamide a ribonucleoside 5 a [chaperone- dihydrofolate cytidylyltransferase: a 5-methylaminomethyl- 8-oxoguanine α H O palmitoyl-CoA H O glutamate-O lauroyl-CoA H O sec ribosylamino)uracil propanoyl-CoA E1 component -Kdo-(2->6)- a palmitoleoyl-[acp] adenylated- cys DL-allothreonine an apurinic/ peptidoglycan 2 2 2 repressor LexA ser a tRNA [acp] methyl ester an [2Fe-2S] -octaprenyl) kinase/ thiazole synthase: cob(I)yrinic acid synthase QueC: queC a [protein]- (n) diphosphate in 23S rRNA GTP ATP roseoflavin ADP]-[disordered- reductase: D-ribulose bifunctional a 5,10- ABB29_RS15205 2-(Se-phospho) a [pyruvate dehydrogenase in DNA lipid IV (E. coli) [ThiS sulfur- apyrimidinic site (meso-DAP bifunctional -methyl-ester cluster protein benzene-1,2-diol ABB29_RS07705 L-cysteine a [pyruvate dehydrogenase E2 subunit alpha: pdhA A ribonucleotide- 5'-phosphate transcriptional enoyl-ACP form scaffold ABB29_RS02955 diaminohydroxyphosphoribosylaminopyrimidine phosphomethylpyrimidine a,c-diamide methenyltetrahydrofolate 4-(cytidine 5'- selenouridine 34 in tRNA 2-methylcitrate E2 protein] N 6 -S- carrier protein] 5-phosphate L-kynurenine bifunctional preQ 6 containing) diphosphate 23S rRNA repressor reductase: protein] complex bifunctional 2- kinase: thiD adenosyltransferase: diphospho)-2-C- 0 protein] N -dihydrolipoyl-L-lysinedihydrolipoyllysine- tol-pal system- tol-pal system- RS15410 deaminase/5-amino-6-(5-phosphoribosylamino) 2-[(2R,5Z)-2-carboxy- methylenetetrahydrofolate synthase: prpC acetyldihydrolipoyl-L-lysine LpxL/LpxP family serine (guanine(2069)-N(7) LexA: lexA RS13010 ABB29_RS15060 a tetrahydrofolate polyprenyl-6- 3,4- [corrinoid ABB29_RS02995 methyl-D-erythritol residue bifunctional DNA- endonuclease reductase: GTPase associated chemotaxis associated serine- uracil reductase RibD: ribD 4-methylthiazol-5(2H)- dehydrogenase/ 3-hydroxypropanoyl- Kdo(2)-lipid IV(A) hydroxymethyltransferase: )-methyltransferase bifunctional hydroxyphenol dihydroxy-2- 5-amino-6-(5- HMP-PP adenosyltranferase]- 4-(cytidine 5'- (2S,3S)-2- acetyltransferase: propanoyl-CoA formamidopyrimidine cysteine III: nth lytic murein ABB29_RS13165 HflX: hflX acyl-CoA response regulator acyl-CoA transcriptional -tRNA a pimeloyl-[acp] ylidene]ethyl phosphate methenyltetrahydrofolate a [protein] 3- CoA lauroyl/palmitoleoyl ABB29_RS09410 RlmK/23S rRNA riboflavin kinase/ thiamine methylase/3- butanone-4- phospho-D- cob(II)inamide diphospho) a 5-methylaminomethyl- methylcitrate ABB29_RS02540 glycosylase/ desulfurase: bifunctional DNA- transglycosylase: ABB29_RS13175 [+ 5 isozymes] thioesterase: protein-glutamate thioesterase: repressor ligase: methyl ester 34 nitrosothio- (guanine(2445)-N(2) FAD synthetase: an [Fe-S cluster 10 cyclohydrolase FolD: folD 2-selenouridine DNA-(apurinic acyltransferase: ABB29_RS14575 ABB29_RS12650 methylesterase: LexA: lexA serS diphosphate demethylubiquinol 3- phosphate ribitylamino)uracil 3-hydroxy- thiamine an N - -2-C-methyl- L-alanine bifunctional 2- formamidopyrimidine adenosylcobalamin- ybgC ybgC pimeloyl-ACP biosynthesis myo-inositol in tRNA or apyrimidinic ABB29_RS12550 )-methyltransferase ABB29_RS04165 ABB29_RS11135 cleaved LptA salvage I O-methyltransferase synthase: formyltetrahydrofolate D-erythritol methylcitrate glycosylase/ [+ 2 isozymes] dependent + methyl ester chaperone]-ATP L-kynurenine phosphate 2-hydroxypenta-2,4- site) lyase: mutM acetaldehyde RlmL: rlmKL phosphate H repressor LexA RS12720 UbiG: ubiG ribB thiamine diphosphate salvage II kinase: ispE biosynthesis dehydratase/ a thiocarboxylated- gly DNA-(apurinic ribonucleoside- an N 2 - GDP adenosylcobalamin thiamine synthase: [corrinoid phosphoribosylglycinamide dienoate degradation C1 Compound Utilization and Assimilation roseoflavin an L-seryl- esterase 2-methoxy- 1-deoxy-L- NAD de novo biosynthesis 2-phospho-4-(cytidine Kdo - ala [ThiS sulfur- 2445 kynureninase: D-glucopyranose aconitate 2 or apyrimidinic a mature GlcNAc-1,6- diphosphate methylguanine palmitate a [protein]-α- laurate sec BioH: bioH salvage from cobalamin ABB29_RS07165 adenosyltranferase]- formyltransferase: acetyl-CoA (2Z)-2- AMP MeOH adenine [tRNA ] 6-(all-trans- glycero-tetrulose ARP 4-amino-2-methyl-5- kynU I (from aspartate) 5'-diphospho)-2-C- 6-phosphate hydratase: a [DNA]- acyl-carrier protein (palmitoleoyl) carrier protein] site) lyase: mutM peptidoglycan anhMurNAc- reductase: in 23S rRNA L-glutamate cob(I)inamide ABB29_RS14470 a [protein]- hydroxypenta- a 5'-phospho- 7,8-dihydro- (n) octaprenyl)phenol 4-phosphate pyrimidinemethanol methyl-D-erythritol S-nitrosoglutathione formaldehyde oxidation nucleotide- 4-oxo-2-pentenal -lipid IV γ dinucleotide cob(I)alamin thiamine ABB29_RS14080 [DNA] 8-oxoguanine A (meso-DAP L-Ala- -D-Glu- a 2'- ABB29_RS01930 RS09280 a pimeloyl-[acp] thioredoxin 2-octaprenyl-6- 3-hydroxyanthranilate cob(I)yrinic acid a tetrahydrofolate 2-C-methyl-D- L-cysteine 2,4-dienoate2-keto-4- VII (THF pathway) formaldehyde oxidation 3'-phosphate a reduced phosphate bifunctional thiamine phosphate asp cis-2- containing) DAP-D-Ala deoxyribonucleoside pathway methoxyphenyl 6,7-dimethyl-8- a,c-diamide erythritol 2,4- S-(hydroxymethyl) pentenoate II (glutathione-dependent) a 3'-terminal a 5'-phospho- H O c-type hydroxymethylpyrimidine Ins(3)P methylaconitate 2 8-amino-7- thiamine- hydroxylase: ubiH ribityllumazine 3-hydroxyanthranilate thiamine- adenosyltransferase: glutathione hydratase: formaldehyde unsaturated sugar [DNA] 5'-diphosphate cytochrome kinase/ cyclodiphosphate acetate ancytochrome oxidized oxononanoate an oxidized cob(II)alamin phosphate 2-methoxy-6-all synthase: 3,4-dioxygenase: phosphate ABB29_RS02995 dehydrogenase/ bifunctional ABB29_RS12340 formaldehyde c oxidase phosphomethylpyrimidine synthase: ispF inositol conversion (S)-4-hydroxy- O c-type synthase: bioF thioredoxin kinase: thiL trans-octaprenyl- ABB29_RS06100 2-iminosuccinate class III alcohol aconitate 2 RS12345 ABB29_RS09445 kinase: thiL 2-oxopentanoate a reduced an N-formyl-L- 2069 cob(I)yrinic acid 1,4-benzoquinol kinase: thiD 2-amino-3- adenosylcobinamide 2-C-methyl-D-erythritol- monophosphatase: hydratase 2/2- to acetyl-CoA a 5,10- sn-glycerol a CDP- a guanine cytochrome (8S)-8-amino-7- thiamine dehydrogenase: a 5,10- a uridine 34 ubiquinone-6 O-succinyl-L- γ-L-glutamyl-(S)- O-phospho- a RNA-DNA hybrid acetyl-CoA H O stearoyl-CoA H O an acyl-CoA H O oleoyl-CoA H O a,c-diamide 2,4-cyclodiphosphate ABB29_RS06670 S-(hydroxymethyl) gly diacylglycerol electron-transfer methionylaminoacyl- gly cys in 23S rRNA 2 2 2 2 ser a protein MscL oxononanoate bifunctional 6,7-dimethyl-8-(1- carboxymuconate- thiamine diphosphate ABB29_RS15450 methylisocitrate acetate methylenetetrahydrofolate 3-phosphate homoserine L-homoserine adenosyltransferase: diphosphate HMP-P inositol glutathione methylenetetrahydrofolate in tRNA flavoprotein tRNA 2-aminobutanoate bifunctional ATP- thioredoxin- demethylmenaquinone D-ribityl)lumazine 6-semialdehyde flavodoxin- dehydratase: acnB acetate- bifunctional threonine/serine adenosylmethionine- ABB29_RS02995 monophosphatase: S-(hydroxysulfenamide) 23S rRNA dependent disulfide methyltransferase/2- bifunctional 5-(2-hydroxyethyl) dependent (2R,3S)-2- -CoA methylenetetrahydrofolate S-(hydroxymethyl) ribonuclease acetyl-CoA tol-pal system- tol-pal system- tol-pal system- dehydratase: -8-amino-7- cob(II)alamin- riboflavin synthase: quinolinate ABB29_RS11695 glutathione acetaldehyde tRNA uridine-5- CDP-diacylglycerol-- electron transfer peptide O-succinylhomoserine glutathione O-succinylhomoserine (guanine(2069)-N(7) Clp protease reductase: methoxy-6-polyprenyl- hydroxymethylpyrimidine -4-methylthiazole adenosyl-cobinamide (E)-4-hydroxy- methylisocitrate ligase: acs dehydrogenase/ glutathione HI: rnhA hydrolase: associated associated associated ABB29_RS13090 oxononanoate [corrinoid ABB29_RS09435 carboxymethylaminomethyl(34) glycerol-3-phosphate 3- flavoprotein- deformylase: (thiol)-lyase: synthetase: (thiol)-lyase: )-methyltransferase ATP-binding trxB 1,4-benzoquinol kinase/ phosphate 3-methylbut- acetyl-CoA methenyltetrahydrofolate dehydrogenase/ ribonuclease ABB29_RS07470 acyl-CoA acyl-CoA acyl-CoA L-serine transaminase: carboxylating myo-inositol synthesis enzyme MnmG: mnmG phosphatidyltransferase: ubiquinone ABB29_RS09600 RlmK/23S rRNA adenosyltranferase] methylase UbiE: ubiE phosphomethylpyrimidine quinolinate 2-enyl- methylisocitrate cyclohydrolase FolD: folD class III alcohol ABB29_RS08020 ABB29_RS05315 ABB29_RS08020 thioesterase: thioesterase: thioesterase: ammonia-lyase: subunit RS07480 ABB29_RS01380 riboflavin nicotinate- pgsA oxidoreductase: (guanine(2445)-N(2) HII: rnhB 6-methoxy-3- kinase: thiD diphosphate lyase: prpB dehydrogenase: tRNA uridine-5- cystathionine glutathione cystathionine ybgC ybgC ybgC ABB29_RS08080 ClpA: clpA (7R,8S)- 4-methyl-5-(2- carboxylating nucleotide hydroxylamine a 5,10- ABB29_RS09175 )-methyltransferase a reduced methyl-2-all- bifunctional synthase: ispG ABB29_RS15450 carboxymethylaminomethyl(34) gamma-synthase: synthase: gshB gamma-synthase: acetate pyruvate [+ 2 isozymes] diaminononanoate phosphooxyethyl) nicotinate- diphosphorylase: acetyl-CoA methenyltetrahydrofolate 1-(3-sn- formate a L-methionylaminoacyl- RlmL: rlmKL thioredoxin cob(I)alamin- trans-octaprenyl- riboflavin kinase/ HMP-PP adenosylcobinamide- (E)-4-hydroxy-3- synthesis GTPase MnmE: mnmE CMP ABB29_RS09065 ABB29_RS09065 an N 7 - DNA a nucleoside 5'- a peptide thiazole nucleotide nadC tRNA processing pyruvate succinate bifunctional S-formylglutathione phosphatidyl) an oxidized tRNA dethiobiotin [corrinoid 1,4-benzoquinol GDP methylbut-2-en- H + ubiquinol-6 2069 monophosphate stearate a carboxylate oleate FAD synthetase: methylenetetrahydrofolate electron-transfer methylguanine synthase: bioD adenosyltranferase] diphosphorylase: 1-yl diphosphate 3-methylthiopropanoate -sn-glycerol ophthalmate ABB29_RS11135 thiamine NaMN a 5-carboxymethylaminomethyluridine 34 flavoprotein in 23S rRNA cob(I)yrinic acid nadC a polycistronic dehydrogenase/ S-formylglutathione a 7,8-dihydrofolate 3-phosphate succinate RS07150 phosphate biosynthesis ammonium in tRNA L-homocysteine L-cystathionine dethiobiotin a,c-diamide FMN nicotinate-nucleotide tRNA precursor methenyltetrahydrofolate hydrolase: fghA synthase: NaMN 4-hydroxy- 1,2-dihydroxy-5- NADP adenosyltransferase: 3-demethylubiquinol-8 adenylyltransferase: cyclohydrolase FolD: folD ABB29_RS07165 folate transformations III (E. coli) 3-methylbut- (methylsulfanyl) formate biotin biosynthesis bifunctional nadD an N 10 - ABB29_RS02995 nicotinate-nucleotide 2-enyl pent-1-en-3-oneacireductone synthase adenosylcob(III) bifunctional 2- riboflavin kinase/ Fatty Acid and Lipid Degradation a purine base a [protein]-S- a uridine 34 3-benzyl-3,6 - an N-terminal- Nα,Nε-diacetyl-lysyl- a 1-acyl-2- a supercoiled adenylyltransferase: nicotinate adenine formyltetrahydrofolate 37 UDP a [protein]- + 4-hydroxy- diphosphate dioxygenase: a 5-L-glutamyl- H O an adenosine a uracil in DNA an ADP-sugar BioB: bioB NAD alamin-[corrinoid polyprenyl-6- FAD synthetase: thiamine a tetrahydrofolate lesion in DNA an amino acid sulfanyl-L-cysteine in tRNA diphosphate 2 DMAPP bis(cysteinylglycine) L-methionyl-L- D-alanyl-D-alanine arachidonoyl- duplex DNA L-histidine nadD dinucleotide 3-methylbut- reductase: ABB29_RS03750 a tRNA precursor a tRNA precursor with formyltetrahydrofolate [peptide] hypoxanthine in tRNA ribonucleotide- RS10315 NAD kinase: adenosyltranferase] hydroxyphenol ABB29_RS11135 phosphate 3-(methylsulfanyl) oleate β-oxidation PRPP - 6-(hydroxymethyl) threonyl-[protein] sn-glycerol ATP- two- 9-mercaptodethiobiotin nicotinate adenine NAD+ synthase: NAD+ synthase: 2-enyl ispH with a 5' extension a 5' extension and fatty acid β-oxidation I (generic) deformylase: purU diphosphate reductase: ABB29_RS06155 cob(I)yrinic acid methylase/3- propanoate -diketopiperazine 3-phosphate CTP dependent component FAD thiamine- dinucleotide ABB29_RS06905 ABB29_RS06905 methionine diphosphate and a long 3' trailer a short 3' extension bifunctional DNA- tRNA 2- ABB29_RS13165 uracil-DNA penicillin- ADP + demethylubiquinol 3- RdgB/HAM1 family tRNA (adenosine(37)-N6) type I methionyl DNA system biotin NADP a,c-diamide phosphate reductase: formate gamma- thiouridine(34) ABB29_RS13175 glycosylase: binding compounds NAD+ synthase: synthase: metH ribonuclease P oleate a (3Z)-alk-3- formamidopyrimidine hypoxanthine-guanine non-canonical -dimethylallyltransferase helicase sensor synthase adenosyltransferase: O-methyltransferase kinase: thiL + glutamyltransferase: ggt membrane aminopeptidase: hydrolase NAD ispH protein component: enoyl-CoA glycosylase/ phosphoribosyltransferase: synthase adenosylcobalamin- ung protein BioB: bioB ABB29_RS02995 UbiG: ubiG ABB29_RS06905 dihydrofolate IPP ribonuclease long-chain fatty gamma- purine NTP MiaA: miaA dipeptidase: map NudE: nudE RecG: recG histidine thiamine ribonuclease ABB29_RS00930 DNA-(apurinic ABB29_RS03265 MnmA: mnmA dependent 2: mrdA reductase: D: rnd acid--CoA ligase: glutamyltransferase: ggt pyrophosphatase: ABB29_RS15375 [+ 3 isozymes] kinase CcmE diphosphate + molybdopterin biosynthesis D: rnd ribonuclease or apyrimidinic biotin adenosylcobalamin ubiquinol-8 NAD ABB29_RS02955serine a tRNA precursor with rdgB 6 ribonucleoside- an apyrimidinic uracil a single CreC: creC bis(guanylyl molybdopterin) cofactor sulfurylation PH: rph ABB29_RS05180 site) lyase: mutM N -(3-methylbut- an N-terminal L- an α-D-aldose a [protein]- a 7,8-dihydrofolate hydroxymethyltransferase:a 5-methyltetrahydrofolate a short 3' extension a [protein]- a 2-thiouridine 34 diphosphate reductase: site in DNA Nα,Nε-diacetyl- a CDP-1-acyl- stranded DNA a (2E)-2- an α-(5-L- [+ 3 isozymes] 2-en-1-yl)- 3-benzyl-3,6 - met threonyl-[protein] 1-phosphate N-phospho- ABB29_RS09410 glycine cleavage system oleoyl-CoA L-cysteine in tRNA 37 ABB29_RS01930 lysyl-D-alanine D-ala 2-arachidonoyl- AMP molybdenum a tRNA precursor enoyl-CoA glutamyl)- a peptide IMP adenosine bis(cysteinyl)- 6- gly L-histidine cys ATP thymidylate aminomethyltransferase a [DNA]- a 5'-phospho- a modified dUDP glycerol cofactor biosynthesis GTP DMAPP with a 5' extension a 2,3,4-saturated 4-oxo-2-pentenal amino acid in tRNA (hydroxymethyl) GcvT: gcvT a (6S)-5-formyltetrahydrofolate a 2,3,4- nucleotide- + cys synthase: bifunctional ribonuclease ribonuclease fatty acid long-chain fatty [DNA] nucleobase phosphate H -diketopiperazine CcmA glutathione S-adenosyl-L-methionine salvage II menaquinol-7 biosynthesis cysteine saturated (3R)-3- 3'-phosphate molybdopterin molybdopterin- ABB29_RS02950 [+ 3 isozymes] methylenetetrahydrofolate PH: rph D: rnd acid--CoA ligase: molybdate biosynthesis desulfurase: GTP 3',8- 5-formyltetrahydrofolate ribonuclease P a 2,3,4- hydroxyacyl-CoA all-trans- synthase cysteine dehydrogenase/ (2E,9Z)- ABB29_RS05180 a 2,3,4-saturated ABB29_RS14575 cyclase cyclo-ligase: protein component: saturated (3S)-3- heptaprenyl 1,4-dihydroxy- bis(guanylyl adenylyltransferase desulfurase: methylenetetrahydrofolate methenyltetrahydrofolate octadecenoyl-CoA fatty acyl CoA SAH an [L-cysteine folate polyglutamylation MoaA: moaA ABB29_RS07205 hydroxyacyl-CoA 34 32 an [L-cysteine lipid II (meso a 2'- a peptidoglycan (E)-4-hydroxy-3- cys glu reductase [NAD(P)H]: metF ABB29_RS00930 a 5,10- a 2-thiouridine a cytosine + dCDP 4-nitrophenyl diphosphate 2-naphthoate molybdopterin) cofactor MoeB: moeB ABB29_RS14575 (8S)-3',8-cyclo-7,8- a lipid II a peptidoglycan a protein with glutathione NADPH NAD Ala acetyl-CoA L-canavanine desulfurase]-S- cyclohydrolase FolD: folD methylenetetrahydrofolate in tRNA desulfurase]-S- diaminopimelate deoxyribonucleoside [DNA] a glycyl-[tRNA ] butanoate dimer (S. aureus) methylbut-2-en- molybdopterin adenosylhomocysteinase: formate a carboxy-adenylated an [L-cysteine dihydroguanosine a 5,10-methylenetetrahydrofolate a 5,10-methenyltetrahydrofolate in tRNA a disulfide bond ribonucleotide- ATP sulfanyl-L-cysteine sulfanyl-L-cysteine containing) 5'-triphosphate RNA 1-yl diphosphate acetyl-CoA FucP adenine ABB29_RS07760 dehydrogenase a tetrahydrofolate [small subunit of desulfurase]-S- 5'-triphosphate Carbohydrate Biosynthesis diphosphate reductase: flavodoxin- molybdate glutamate-- cysteine carboxylase dinucleotide L-homocysteine accessory molybdopterin synthase] sulfanyl-L-cysteine cyclic pyranopterin bifunctional (S)-3-hydroxy-(9Z) coenzyme A a 2,3,4-saturatedacetyl-CoA C-a 2,3,4-saturated tRNA uridine-5- monofunctional NAD(P)(+) ABB29_RS13165 penicillin- dependent cysteine ligase: desulfurase: methylenetetrahydrofolate -octadecenoyl-CoA biosynthetic tRNA 2- monofunctional DNA polymerase D-tyrosyl-tRNA(Tyr) arylesterase: binding (E)-4-hydroxy- biotin arginase: sulfurtransferase serine monophosphate gluconeogenesis I an uncharged tRNA fatty acyl CoAacyltransferase:3-oxoacyl-CoA carboxymethylaminomethyl(34) glutaredoxin transhydrogenase ABB29_RS13175 ABB29_RS12975 ABB29_RS14575 bifunctional α CMP-3-deoxy-D- GDP-mannose biosynthesis thiocytidine(32) biosynthetic III subunit chi: deacylase: ABB29_RS02640 polynucleotide carboxylase rocF molybdopterin 5-methyltetrahydropteroyltriglutamate- demethylmenaquinol-7 FdhD: fdhD synthase dehydrogenase/ UDP- -D- ABB29_RS04750 synthesis enzyme MnmG: mnmG peptidoglycan (Re/Si-specific): protein 3-methylbut- a [bis(guanylyl hydroxymethyltransferase: tetrahydrofolate manno-octulosonate synthetase 3: grxC peptidoglycan ABB29_RS09250 adenosylcobalamin- ABB29_RS09545 adenylyltransferase subunit: accC molybdotransferase - homocysteine S- MoaC: moaC NAD salvage pathway III bis(guanylyl molybdenum methenyltetrahydrofolate galactose transglycosylase: ABB29_RS15615 2: mrdA 2-enyl- γ bifunctional molybdopterin) ABB29_RS09410 synthase/ an N 10 - (S)-malate biosynthesis D-glucopyranose tRNA uridine-5- TtcA: ttcA transglycosylase: dependent PcnB: pcnB [+ 3 isozymes] MoeA: -L-glutamyl- methyltransferase: metE [bis-MGD cofactor a thiocarboxylated (to nicotinamide riboside) cofactor) biosynthesis cyclohydrolase FolD: folD biosynthesis mtgA [+ 7 isozymes] ABB29_RS15635 diphosphate RS10045 demethylmenaquinone cofactor chaperone]- dihydrofolate formyltetrahydrofolate cyclic pyranopterin D-ribulose 6-phosphate 3-oxo-(9Z)- carboxymethylaminomethyl(34) a protein with mtgA ribonucleoside- butanoate 4-nitrophenol urea ABB29_RS04800 L-cysteine methionine synthase: metH chaperone]-bis-MGD [small subunit of UDP-α-D-glucose glucose-6- ABB29_RS15640 a peptidoglycan 2-C-methyl-D-synthase: ispG malonyl-CoA L-canaline S-sulfanyl-L-cysteine a 5,10- synthase: folC phosphate + MoO - 10 5-phosphate synthesis GTPase MnmE: mnmE 32 an [L-cysteine GSSG diphosphate reductase: Ala methyltransferase/2- bifunctional molybdopterin synthase] NADP 2 an N -formyltetrahydrofolate malate D-arabinose phosphate octadecenoyl-CoA a 2-thiocytosine reduced L- a tRNA gly molybdopterin glutathione methylenetetrahydrofolate molybdopterin UDP-glucose lipoprotein posttranslational di-trans,octa-cis desulfurase]- ABB29_RS01930 with D,D cross- D-ala RNA erythritol-2,4- synthetase: met methoxy-6-polyprenyl- tetrahydrofolate molybdopterin dehydrogenase: 5-phosphate isomerase: pgi acetyl-CoA C- acetyl-CoA a peptidoglycan -undecaprenyl in tRNA cysteine residues lipid II (meso di-trans,octa-cis [DNA] link (S. aureus) cyclodiphosphate molybdotransferase 1,4-benzoquinol formate bifunctional molybdopterin cofactor 4-epimerase modification L-cysteine CDP a tetrahydrofolate synthase/ ABB29_RS13975 isomerase: F6P acyltransferase: a 5-aminomethyl-2- -undecaprenyl + MoeA: ABB29_RS05315 dehydrogenase NAD GalE: galE a 7,8-dihydrofolate diphosphate diaminopimelate NADH NADP methionine methylase UbiE: ubiE tetrahydrofolate synthase: + a [prolipoprotein]- ABB29_RS04750 34 glutathione accessory dihydrofolate NAD molybdenum cofactor phosphorylation and UDP-α-D-galactose aldehydo-D-ABB29_RS14440 thiouridine in tRNA containing) diphosphate ABB29_RS01785 adenosyltransferase: synthase/ ABB29_RS15145 mannose-1-phosphate L-cysteine YajC synthase: sulfurtransferase synthase: folC glutathione- guanylyltransferase: transhydrogenation pyruvate arabinose 5- ABB29_RS07775 menaquinol-7 dihydrofolate NAD(+) oxaloacetate guanylyltransferase/ (7Z)-hexadecenoyl-CoA MoO - an N 10 - glutaredoxin prolipoprotein 2 gshB FdhD: fdhD ABB29_RS01780 + phosphate UDP-N-acetyl-α-D-muramoyl- a 2'- an N-terminal- an N-terminal- a peptide with synthase: folC diphosphatase: NAD mannose-6- diacylglyceryl di-trans,octa-cis- an L-arginyl- an (R)-2- an N-acylated- a D-aspartyl- a [protein]-L- (S)-1-pyrroline- molybdopterin formyltetrahydrofolate redox reactions molybdopterin phosphoenolpyruvate L-alanyl-γ-D-glutamyl-L- cob(II)alamin 3-methylbutanoate a protein deoxyribonucleoside L-methionyl-L- ω L-methionyl- an N-terminal carbonic acid glutathione SAM glutathione- a 5,10- nudC NAD kinase: phosphate isomerase: transferase: undecaprenyl phosphate ATP [tRNA Arg ] halocarboxylate [DNA] [tRNA asp ] proline ( = 180) 5-carboxylate IMP cofactor sulfo-bis(guanylyl bis(molybdenum synthase: ppsA 5'-triphosphate D-amino acid cysteinyl-[protein] FKBP-type bifunctional glycyl-[protein] L-methionine peroxide methylenetetrahydrofolate glutathione lipoate biosynthesis ABB29_RS06155 ABB29_RS09115 ABB29_RS02945 lysyl-D-alanyl-D-alanine molybdopterin) cofactor NMN cofactor) peptidyl-prolyl cis- proline 5'/3'-nucleotidase bis(guanylyl tungstenpterin) redox reactions and incorporation I NADP + D-arabinofuranose D-mannopyranose a [prolipoprotein]- (2E,7Z)- acetate- carbonate HAD family trans isomerase: dehydrogenase/L- SurE: surE RS05270 cofactor biosynthesis molybdenum cofactor phosphoenolpyruvate 5-phosphate 6-phosphate S-1,2-diacyl-sn- hexadecenoyl-CoA phospho-N- cob(I)yrinic acid -CoA DNA polymerase D-aminoacylase: type I methionyl D-tyrosyl-tRNA(Tyr) type I methionyl type I methionyl dehydratase: GSSG a reduced 5'-nucleotidase: guanylyltransferase: acetylmuramoyl- arginyltransferase: hydrolase: ABB29_RS09885 glutamate gamma- 5'-nucleotidase: menaquinol-6 biosynthesis NAD(P) 3-deoxy-8- phosphomannomutase/ glyceryl-L-cysteine Nucleoside and Nucleotide Degradation a,c-diamide ligase: acs III subunit delta: ABB29_RS06615 aminopeptidase: deacylase: aminopeptidase: aminopeptidase: can guanylyl molybdenum glutaredoxin an octanoyl-[acp] ABB29_RS06145 ABB29_RS01780 pentapeptide- ABB29_RS08455 ABB29_RS12390 [+ 6 isozymes] semialdehyde ABB29_RS06145 transhydrogenase: phosphopyruvate phosphooctulonate phosphoglucomutase: adenosyltransferase: ABB29_RS11565 D-aminoacylase: map ABB29_RS09545 map map cofactor biosynthesis GTP lipoyl(octanoyl) 1-(β-D bis(guanylyl transferase: HAD family a [protein]-L- dehydrogenase inosine bis(tungstenpterin) ABB29_RS15615 hydratase: eno synthase: kdsA ABB29_RS09120 signal ABB29_RS02995 [+ 8 isozymes] ABB29_RS15530 ω MoO - glutathione- demethylmenaquinol-6 glutaredoxin transferase ribofuranosyl) molybdopterin) (S)-3-hydroxy-(7Z) inosine 5'- ABB29_RS06785 3-methylbutanoyl- hydrolase: proline ( = 0) PutA: putA 2 cofactor ABB29_RS15635 α peptidase UTP and CTP dephosphorylation I pyrimidine deoxyribonucleotides an N-terminal CO H O bifunctional 3: grxC LipB: lipB -D-mannose S-methyl-5'- diphosphate Arg an N-terminal L- an N-terminal 2 2 molybdopterin disulfide a [lipoyl-carrier protein] nicotinamide cofactor 2-phospho-D-glycerate -hexadecenoyl-CoA phosphate AMP CoA a tRNA ABB29_RS14435 asp KDO-8P II: lspA dephosphorylation thioadenosine arginyl-[protein] met tRNA D-aspartate glu met met a peptide RS10190 reductase: demethylmenaquinone a protein with 6 NADPH 1-phosphate degradation adenosylcobalamin cysteinyl-[protein] glycyl-[protein] cofactor molybdenum cofactor molybdenum cofactor N -octanoyl-L-lysine UTP undecaprenyl-diphospho-N- triphosphate [DNA] a carboxylate gorA methyltransferase/2- reduced L- 2,3-bisphosphoglycerate- mannose-1-phosphate nucleoside triphosphate degradation III UMP a D-amino acid guanylyltransferase: guanylyltransferase: lipoyl 3-deoxy-D-manno- an (S-diacyl- a lipoprotein S-methyl-5'- acetylmuramoyl-L-alanyl-γ-D- an (S)-2- guanylyl methoxy-6-polyprenyl- cysteine residues independent UDP-N-acetyl-D- guanylyltransferase/ IMP pyrophosphohydrolase: a halide anion ABB29_RS01780 ABB29_RS01780 synthase: lipA octulosonate sn-glyceryl) signal peptide CTP synthase: thioadenosine glutamyl-L-lysyl- D-alanyl-D-alanine hydroxycarboxylate molybdenum 1,4-benzoquinol phosphoglycerate glucosamine biosynthesis I mannose-6- 3-oxo-(7Z)- IMP mazG a [lipoyl-carrier 8-phosphate -L-cysteinyl- signal ABB29_RS15225 dCTP dCMP RS09075 cofactor methylase UbiE: ubiE mutase: phosphate isomerase: hexadecenoyl-CoA dehydrogenase: bis(guanylyl glutathione 6 D-glucopyranose phosphatase: [apolipoprotein] menaquinol-6 protein]-N -[(R)- Polyprenyl Biosynthesis ABB29_RS13605 peptide acetyl-CoA C- UDP S-methyl-5'- UDP-N-acetyl-α-D- N-acetyl-muramoyl-(L- an N-terminal- a peptidyl- CcmB tungstenpterin) cofactor 6-phosphate ABB29_RS14435 ABB29_RS09115 guaB CTP di-trans,octa-cis- quinoxaline-2- an (S)-2- a [protein]- a D-tyrosyl- β-citryl-L- dihydrolipoyl]-L-lysine glucose-6- peptidase acyltransferase: XMP nucleoside triphosphate thioinosine muramoyl-L-alanyl-γ-D- aryl-carrier protein 2-methylbutanoate hydrogen selenide O-acetyl-L-serine a [protein]-L-lysine alanyl-γ-D-glutamyl-L- a tRNA precursor a DNA segment L-methionyl-L- dipeptidase Ap4A a protein α SppA: sppA undecaprenyl phosphate carboxyl adenylate halocarboxylate L-glutamine [tRNA Tyr ] glutamine di-trans,poly-cis 3-phospho-D-glycerate phosphate α-Kdo GDP- -D-mannose ABB29_RS04750 pyrophosphohydrolase: S-methyl-5'- glutamyl-L-lysyl-D-alanine lysyl-D-alanyl-D-alanine) recombinase alanyl-[protein] Dcp substrate symmetrical an N-acyl-(S- ATP- -undecaprenyl isomerase: pgi 5'/3'-nucleotidase mazG thioinosine RecA: recA bis(5'-nucleosyl)- dependent phosphoglycerate 3-deoxy-manno- diacyl-sn-glyceryl) a peptide (5Z)-tetradecenoyl-CoA UMP acetate- HAD family transglutaminase phosphate biosynthesis F6P SurE: surE CDP dUTP diphosphatase: dut phosphorylase: phospho-N- acyl carrier cysteine penicillin- D-tyrosyl-tRNA(Tyr) recombinase RecT: type I methionyl peptidyl- tetraphosphatase: protease RS01305 kinase: octulosonate -L-cysteinyl- dUTP dUMP -CoA hydrolase: domain-containing ribonuclease N-formylglutamate (2E,6E)-farnesyl 5'-nucleotidase: 5'/3'-nucleotidase ABB29_RS03270 acetylmuramoyl- protein: acpP synthase binding deacylase: ABB29_RS12140 aminopeptidase: dipeptidase ABB29_RS02960 subunit IPP ABB29_RS07525 glutamine-- cytidylyltransferase: [lipoprotein] ligase: acs ABB29_RS12390 protein: D: rnd a DNA segment deformylase: hutG RS10255 diphosphate ABB29_RS06145 SurE: surE pentapeptide- [+ 2 isozymes] A: cysK protein ABB29_RS09545 map Dcp: dcp HslV: hslV lipid IV biosynthesis (P. putida) Cell Structure Biosynthesis fructose-6- kdsB ABB29_RS00405 in reverse A lipid IV biosynthesis (E. coli) peptidoglycan maturation (meso-diaminopimelate containing) 5-MTR-1-P HAD family ADP A 13-DPG 5'-nucleotidase: transferase: 2: mrdA orientation phosphate 5-hydroxy-CTP 5-hydroxy-CMP (2S)-2- hydrolase: a peptide a (3R)-3- di-trans,poly-cis- CMP-Kdo UDP-α-D-glucose (2E,5Z)- xanthosine CMP ABB29_RS06145 ABB29_RS06785 a (3R)-3- lipid II (meso transaminase queuosine biosynthesis I (de novo) a quinoxaline-2- methylbutanoyl- diphosphate acetate L-selenocysteine ABB29_RS14435 a protein with an a nucleoside 5'- an N-terminal L- citrate hydroxydecanoyl- UDP-N-acetyl- decaprenylcistransferase: type I biosynthesis tetradecenoyl-CoA 5'/3'-nucleotidase AMP N-acetyl-muramoyl-(L- D-tyrosine a tRNA Tyr a tRNA met gln a dipeptide a peptide hydroxytetradecanoyl- UDP-N-acetyl- diaminopimelate containing) Amine and Polyamine Biosynthesis (isomerizing) uridine AMP carboxyl-[aryl- CoA N 6 -(γ-glutamyl)- monophosphate alanyl-[protein] RS08885 [acp] α uppS glyceraldehyde- undecaprenyl-diphospho-N γ -D-glucosamine [acp] α-D-glucosamine : glmS D-glucopyranose SurE: surE UMP carrier protein] L-lysine crosslink alanyl- -D-glutamyl- D-ala RS05525 monofunctional 3-phosphate preQ -acetylmuramoyl-L-alanyl-γ- an (S)-2- spermidine biosynthesis III D-glucosamine 6-phosphate 0 5'-nucleotidase: a halide anion L-lysyl-D-alanine) acyl-ACP--UDP-N- biosynthetic di-trans,octa-cis triose-phosphate dehydrogenase: phosphomannomutase/ NADPH-dependent 7- D-glutamyl-L-lysyl- D-alanine hydroxycarboxylate acyl-ACP--UDP-N- 6-phosphate ABB29_RS06145 acetylglucosamine O- peptidoglycan -undecaprenyl isomerase: gap dTDP-β-L-rhamnose phosphoglucomutase: cyano-7-deazaguanine (3E,5Z)-tetradeca- (S)-3-hydroxy-(5Z) acetylglucosamine O- transglycosylase: diphosphate ABB29_RS09120 reductase QueF: queF xanthine cytidine acyltransferase: lpxA arg ABB29_RS10505 D-glyceraldehyde phosphoglucosamine biosynthesis α-D-glucopyranose 3,5-dienoyl-CoA -tetradecenoyl-CoA β α acyltransferase: lpxA undecaprenyl- UDP-N-acetyl- undecaprenyldiphospho- N-acetyl- -D-glucosamine- a peptidoglycan a [protein chain a peptide with 37 an N-terminal- a [lipoyl-carrier 5-deoxy- - mtgA SAM DHAP mutase: glmM preQ xanthine:NAD+ + an (S)-2- a guanine β RS02435 3-phosphate 1-phosphate 1 α MoO - phylloquinone NAD(P)H H -citryl-L- 6 spermidine biosynthesis I diphosphate α-D-glucopyranose -D-glucosamine N-acetylmuramoyl-L- 2 1,6-anhydro-N- dimer (generic) (R)-β-lysine elongation factor an N-terminal asp O-ureido-L- L-methionyl-L- protein]-N -[(R) a protein D-ribose 1- UDP-3-O-[(3R)-3- UDP-3-O-[(3R)-3- a nascent peptidoglycan α-D-glucosamine oxidoreductase: molybdopterin GTP halocarboxylate in tRNA glutamate RS02005 arginine 1-phosphate UTP--glucose- alanyl-γ-D-glutamyl-meso molybdopterin acetyl-β-D-muramate EF-P]-L-lysine 34 L-proline homoserine tRNA seryl-[protein] -dihydrolipoyl]- phosphate hydroxydecanoyl]- with (L-alanyl-γ-D-glutamyl- adenosylmethionine phosphatase: tRNA guanosine(34) ABB29_RS12770 metalloprotease S-methyl-5- hydroxymyristoyl]-N- decarboxylase: 1-phosphate glucose-1-phosphate 1-phosphate -2,6-diaminopimeloyl- cofactor (guanosine(37)-N1) L-lysine dihydrolipoyl N-acetyl-α-D- α meso-2,6-diaminopimeloyl-D- ABB29_RS00550 transglycosylase Tgt: tgt (3E,5Z)- 3-oxo-(5Z)- lytic murein PmbA: pmbA thioribose-1- acetyl- -D-glucosamine speA decarboxylase: speD SAM di-trans,octa-cis bifunctional UDP-N- thymidylyltransferase NAD(P)H:quinone HAD family -methyltransferase glucosamine alanyl-D-alanine) pentapeptide fructose- uridylyltransferase a 7-aminomethyl-7- tetradecadienoate tetradecenoyl-CoA urate D-alanyl-D-alanine beta-N- transglycosylase: EF-P lysine argininosuccinate type I methionyl dehydrogenase: metalloprotease phosphate UDP-3-O-acyl-N- -undecaprenyl acetylglucosamine RfbA: rfbA molybdenum cofactor oxidoreductase: wrbA hydrolase: prolyl TrmD: trmD N-formylglutamate UDP-3-O-acyl-N- bisphosphate α GalU: galU 34 acetyl-CoA C- acetylhexosaminidase: ABB29_RS12650 aminoacylase synthase: an N 1 - aminopeptidase: lpdA TldD: tldD isomerase: acetylglucosamine agmatine dAdoMet diphosphorylase/ dTDP- -D-glucose deazaguanosine in tRNA undecaprenyldiphospho- NAD(P)H:quinone ABB29_RS12390 aminopeptidase: pip deformylase: hutG RS00800 acetylglucosamine adenosylmethionine phosphate guanylyltransferase: nagZ ABB29_RS03625 37 map deacetylase: penicillin-binding penicillin-binding aldolase class I: UDP-α-D-glucose tRNA preQ1(34) S- acyltransferase: muramoylpentapeptide beta-N- [+ 2 isozymes] GenX: genX methylguanine dihydrolipoyl a peptide 5-deoxy-D-mtnA deacetylase: decarboxylase: speD glucosamine-1- dTDP-glucose 4,6- Detoxification ABB29_RS01780 oxidoreductase: wrbA HAD family SecE ABB29_RS06825 protein 2: mrdA protein 2: mrdA ABB29_RS07545 adenosylmethionine ABB29_RS04750 acetylglucosaminyltransferase: in tRNA dehydrogenase: ribulose 1- ABB29_RS06825 a mature peptidoglycan with polyamine phosphate N- dehydratase: rfbB hydrolase: a [lipoyl-carrierlpdA UDP-3-O-(3- putrescine dAdoMet ribosyltransferase- (3Z)-dodec- murG 1,6-anhydro-N- GlcNAc-1,6- [a protein chain an N-terminal phosphate UDP-3-O-(3- a nascent peptidoglycan a nascent peptidoglycan (L-alanyl-γ-D-glutamyl-meso- aminopropyltransferase: acetyltransferase dTDP-4-dehydro-6- reactive oxygen species degradation bis(guanylyl GlcNAc ABB29_RS14435 a lipid II a peptide pro canavaninosuccinate citrate glu protein]-N 6 -[(R hydroxymyristoyl) α isomerase QueA: queA 3-enoyl-CoA arsenate arsenate NAD(P) + phylloquinol acetyl-β-muramate anhydro-MurNAc- elongation factor met L-seryl-[protein] hydroxydecanoyl) with (L-alanyl-γ-D-glutamyl- with D,D cross-links (meso- speE GlmU: glmU deoxy- -D-glucopyranose 8-oxo-(d)GTP detoxification I molybdopterin) )-lipoyl]-L-lysine RS08675 -α-D-glucosamine 2,6-diaminopimeloyl-D-alanyl- β-D-fructose 1,6- detoxification detoxification lipid II (meso pentapeptide EF-P]-N-(β-L- RS14560 -α-D-glucosamine meso-2,6-diaminopimeloyl- diaminopimelate containing) N-acetyl-α-D- dTDP-4- 34 UDP cofactor LptC UDP-3-O-(3- D-alanine) pentapeptide polyamine bisphosphate an epoxyqueuosine in tRNA superoxide a (2R)-2- lysyl)-L-lysine 34 UDP-3-O-(3- D-alanine) tetrapeptide N 1 -(3-aminopropyl) dehydrorhamnose II (glutaredoxin) III (thioredoxin) diaminopimelate containing) a halide anion hydroxymyristoyl) aminopropyltransferase: glucosamine PRPP biosynthesis hydroxy fatty acid RS03120 hydroxymyristoyl) agmatine class 1 fructose- 3,5-epimerase: rfbC dGTP GTP glucosamine N- speE 1-phosphate tRNA (2E)-dodec- superoxide dismutase: arsenate arsenate glucosamine N- bisphosphatase: dTDP-4-dehydro- D-ribose 5- epoxyqueuosine(34) arsenate reductase arsenate reductase acyltransferase: a mature peptidoglycan bifunctional UDP-N- 2-enoyl-CoA ABB29_RS12270 6 4 acyltransferase: ABB29_RS00825 β-L-rhamnose phosphate reductase QueG: queG (glutaredoxin): arsC (glutaredoxin): arsC N -(3-methylbut- a [protein]- an O - all-trans- an (R)-2- a [protein]- a peptide with 1,6-anhydro-N- an N-terminal- a cis-delta21-39- an unstable RS12860 lpxD with D,D cross-links (meso- Kdo transfer to acetylglucosamine ribose-phosphate a proteinogenic leukotriene-C4 FAD leukotriene-D4 chitin L-methionyl-L- RNA RecA filament- RS05805 lpxD a nascent peptidoglycan a nascent peptidoglycan with a nascent peptidoglycan a mature peptidoglycan spermidine dTDP-4- 8-oxo-dGTP 8-oxo-GTP a sulfurated [sulfur carrier] 2-en-1-yl)- L-cysteine methylthymine 4-hydroxybenzoate nonaprenyl halocarboxylate L-threonine an N-terminal acetyl-β-muramate L-kynurenine oxo-40-methyl- UDP-2-N,3-O-bis[(3R)- diaminopimelate containing) lipid IV I (E. coli) F6P diphosphorylase/ diphosphokinase: 34 hydrogen peroxide arsenate reductase arsenate reductase 37 amino acid UDP-2-N-[(3R)-3- with L,D cross links (meso- (L-alanyl-γ-D-glutamyl-meso- with (L-alanyl-γ-D-glutamyl- with (L-alanyl-γ-D-glutamyl- A a queuosine in tRNA adenosine in tRNA in DNA diphosphate Xaa-L-proline anhydro-N- valyl-[protein] C59:1-[acp] DNA complex RS12840 3-hydroxytetradecanoyl]- spermidine glucosamine-1- dehydrorhamnose ABB29_RS15740 (glutaredoxin): arsC (glutaredoxin): arsC cyclopropane DNA hydroxydodecanoyl]- α diaminopimelate containing) 2,6-diaminopimelate) tripeptide meso-2,6-diaminopimeloyl- meso-2,6-diaminopimeloyl- CMP-Kdo lipid IV (E. coli) glucose-6- reductase: rfbD (S)-3- arsenite arsenite 8-oxo-dGTP beta-N- acetylmuramic fatty acyl repair RS15675 -D-glucosamine A phosphate N- PRPP HAD family FAD:protein FMN membrane 3-O-[(3R)-3- glycine) tetrapeptide D-alanine) tetrapeptide phosphate hydroxydodecanoyl-CoA catalase: diphosphatase: gamma- methylated-DNA-- 4-hydroxybenzoate Xaa-Pro acetylhexosaminidase: acid kinase: type I methionyl ribonuclease phospholipid protein UDP-2,3- acetyltransferase dTDP-β-L-rhamnose tRNA (N6-isopentenyl hydrolase: transferase: dipeptidase: kynureninase: hydroxydecanoyl]- isomerase: pgi ABB29_RS05730 ABB29_RS10360 glutamyltransferase: ggt [protein]-cysteine S- octaprenyltransferase: aminopeptidase: nagZ ABB29_RS00020 aminopeptidase: PH: rph synthase: cfa RecO: diacylglucosamine 3-deoxy-D-manno- GlmU: glmU adenosine(37)-C2)- ABB29_RS12390 ABB29_RS14535 ABB29_RS15375 N-acetyl-D- kynU α-D-glucosamine [+ 2 isozymes] 8-oxo-GMP methyltransferase: ubiA pepP map a cis-keto-C60- recO RS00305 diphosphatase: a mature peptidoglycan a mature peptidoglycan with octulosonic acid D-glucopyranose UDP-N-acetyl- 5-oxo-L-proline metabolism H O hydroxyl radical 8-oxo-dGMP methylthiotransferase gamma- muramate 6- a stabilized LolB 2 ABB29_RS14215 HAD family meroacyl-[acp] RS11090 UDP-2,3- ABB29_RS07780 with L,D cross-links (meso- (L-alanyl-γ-D-glutamyl-meso- a mature peptidoglycan 6-phosphate α-D-glucosamine MiaB: miaB glutamyltransferase: ggt N-acetyl-D- phosphate RecA filament- transferase: a [protein] with a [protein] with arsenite arsenite hydrolase: a [protein]-FMN- chitin a nucleoside RNA diacylglucosamine diaminopimelate containing) 2,6-diaminopimelate) tripeptide with (L-alanyl-γ-D-glutamyl- 3-oxododecanoyl-CoA O 3-nonaprenyl-4- a peptide with leukotriene-E4 glucosamine an N-terminal DNA complex MurJ UDP-2,3- ABB29_RS12545 2 ABB29_RS14435 L-threonine a proteinogenic gly anthranilate diphosphate diphosphatase: an N-terminal an N-terminal 6 a [protein]-S- AMP ala diacylglucosamine meso-2,6-diaminopimeloyl- Kdo transfer to lipid N -(3-methylbut-2-en- α γ a thymine in DNA hydroxybenzoate an N-terminal met L-valyl-[protein] ABB29_RS07780 L-glutamine L-glutamate acetyl-CoA C- 5'-deoxyadenosine an unsulfurated an -( -L-glutamyl) leukotriene-D4 methyl-L-cysteine amino acid diphosphatase: lpxH glycine) tetrapeptide IV II (Haemophilus) α-Kdo-(2->6)- 1-yl)-2-(methylsulfanyl) met L-proline A acyltransferase: arginine -L-amino acid UDP-2,3- lipid IV (E. coli) adenosine 37 in tRNA [sulfur carrier] a (2R)-2- RS14180 A dependent a halide anion RS07830 diacylglucosamine lipid X CMP-Kdo lipid IV (E. coli) ABB29_RS04750 hydroxy fatty acid A acid resistance RS16195 diphosphatase: lpxH lipid-A- a [protein] with decanoyl-CoA LptB 6 3-deoxy-D-manno- α-Kdo-(2->4)- arg a nascent peptidoglycan an O - all-trans- a hypoxanthine a [protein] N- 2251 1498 an L-1- lipid X (P. putida) disaccharide an N-terminal 5- a proteinogenic glutathione a [protein]- a D-aminoacyl- guanosine a uracil citrate octulosonic acid α-Kdo-(2->6)- Fatty Acid and Lipid Biosynthesis arginine (meso-DAP containing) methylguanine heptaprenyl in DNA terminal-formyl- glu ala a protein phosphatidyl- synthase: lpxB oxo-L-proline γ-L-glutamyl amino acid L-cysteine 4-hydroxybenzoate ATP [tRNA] in 23S rRNA in 16S rRNA AMP lipid-A- transferase: lipid IV (E. coli) decarboxylase: in DNA diphosphate a tRNA precursor L-methionine 23S rRNA 16S rRNA bifunctional 2- sn-glycerol RS09380 lipid A disaccharide A glutathione ATP- lipid RS07420 disaccharide 5-phosphate Secondary Metabolite Degradation speA CTP (guanosine(2251) (uracil(1498)-N(3))- 5'/3'-nucleotidase (E. coli) ABB29_RS12545 palmitate biosynthesis (type II fatty acid synthase) pyroglutamyl- lytic murein DNA-deoxyinosine methylcitrate dependent zinc kinase ModB synthase: lpxB octanoyl-[acyl-carrier gondoate biosynthesis (2E)-dec-2-enoyl-CoA agmatine methylated-DNA-- -2'-O)- methyltransferase: SurE: surE tetraacyldisaccharide peptidase transglycosylase: gamma- 4-hydroxybenzoate D-tyrosyl-tRNA(Tyr) glycosylase: peptide dehydratase/ glutamate-- metalloprotease YegS: lipid A α-Kdo-(2->6)- protein] biosynthesis (anaerobic) [protein]-cysteine S- methyltransferase ABB29_RS01385 5'-nucleotidase: RS02395 I: pcp myo-inositol degradation I ABB29_RS12650 glutamyltransferase: ggt octaprenyltransferase: multifunctional deacylase: deformylase: an N 3 - aconitate cysteine ligase: FtsH: ftsH yegS 4'-kinase: lipid IV (E. coli) an acetoacetyl-[acp] (mitochondria, yeast) 4-deoxy-L-threo-hex-4- β-D-glucuronide ABB29_RS02550 ABB29_RS06145 1-(3-sn- disaccharide A long-chain fatty methyltransferase: ubiA CCA addition/ ABB29_RS09545 ABB29_RS09600 RlmB: rlmB 1498 hydratase: ABB29_RS12975 ABB29_RS03960 enopyranuronate degradation and D-glucuronate [+ 2 isozymes] gamma- 2-O- methyluracil a peptide phosphatidyl) (P. putida) 3-deoxy-D-manno- a malonyl-[acp] an oleoyl-[acp] acid activation ABB29_RS14215 repair protein: 2251 ABB29_RS14080 adenosine 3-oxoacyl-ACP an acetoacetyl-[acp] 5-oxo-L-proline myo-inositol degradation glutamyltransferase: ggt methylguanosine in 16S rRNA -sn-glycerol RS07055 tetraacyldisaccharide lipid IV (E. coli) octulosonic 3-oxoacyl-ACP (S)-3- 4-deoxy-L-threo-hex- β ABB29_RS13015 an apurinic site [+ 2 isozymes] BamE A reductase a long-chain a -D- a mature peptidoglycan a nascent peptidoglycan 3-heptaprenyl-4- an N-terminal L- in 23S rRNA γ-L-glutamyl- 3-phosphate RS13985 4'-kinase: acid kinase: reductase 5-oxoprolinase hydroxydecanoyl-CoA inositol 2- 4-enopyranuronate a [protein]-S- an uncharged within DNA hypoxanthine formate FabG: fabG fatty acid glucuronoside with (L-alanyl-γ-D-glutamyl- (meso-DAP containing) α γ a guanine in DNA hydroxybenzoate a D-amino acid methionyl-[protein] D-threo-isocitrate D-alanine ABB29_RS03960 ABB29_RS15120 FabG: fabG beta-ketoacyl- long-chain fatty subunit dehydrogenase: an -( -L-glutamyl) L-cysteinylglycine methyl-L-cysteine a tRNA tRNA RS00865 lipid IV 4-O-phospho-α- 3-oxoacyl-ACP ACP synthase acid--CoA ligase: meso-2,6-diaminopimeloyl- with GlcNAc terminus -L-amino acid A 3-oxoacyl-ACP PxpB: pxpB iolG containing a (P. putida) Kdo-(2->6)-lipid IV reductase II: fabF ABB29_RS05180 D-glucopyranuronate D-alanine) tetrapeptide A Aminoacyl-tRNA Charging reductase a long-chain inositol 2- 5-dehydro-4-deoxy- 3' CCA end FabG: fabG RS06925 FabG: fabG fatty acyl-CoA glu 3-oxodecanoyl-CoA dehydrogenase: D-glucuronate RS06945 a (3R)-3- a (3R)-3- an (11Z)-3-oxo- iolG 5-dehydro- all-trans- a 5,6- (3R)-3- SecY tRNA charging acetyl-CoA C- a [2-oxoglutarate- a uridine 34 a thiocarboxylated all-trans- an [RNA]-3'- a dipeptide with a a mismatched hydroxybutanoyl-[acp] a D-tryptophanyl- 20 an isocitrate hydroxybutanoyl-[acp] icos-11-enoyl-[acp] 4-deoxy-D- a sulfurated SAM dehydrogenase hypoglycin A glutathione [SAMP] C- hexaprenyl glu a (6S)-5- hexaprenyl a [protein] Ser/Thr ribonucleoside- dihydrouracil hydroxypentanoyl- YidC acyltransferase: scyllo-inosose aldehydo-D- in tRNA 4-hydroxybenzoate 4-aminobenzoate [tRNA Trp ] C-terminal L-proline dehydrogenase GMP DNA base pair 3-hydroxyacyl- glucuronate [sulfur carrier] 6 formyltetrahydrofolate diphosphate serine/threonine- in tRNA CoA 3-hydroxyacyl- 3-oxoacyl-ACP periplasmic disulfide bond formation ABB29_RS04750 glucuronate E2 protein] N - terminal glycine diphosphate 2',3'- tRNA bifunctional acetoacetyl- DNA gln a tRNA Gln ACP dehydratase isomerase: protein kinase: cyclophosphate 5'/3'-nucleotidase mismatch ACP dehydratase reductase myo-inosose-2 glucuronate octanoyl-L-lysine RNA 2',3'-cyclic dihydrouridine(20/ isocitrate CoA tRNA asp asp ser a tRNA ser a tRNA Ala ala gly a tRNA Gly phe a tRNA Phe FabZ: fabZ a [DsbB protein] a [DsbA protein] two reduced octanoyl-CoA kduI ABB29_RS00450 Xaa-Pro SurE: surE BamB elongator FabZ: fabZ FabG: fabG an electron- isomerase: gamma- tRNA 2- 4-hydroxybenzoate bifunctional 4-hydroxybenzoate D-tyrosyl-tRNA(Tyr) 20a) synthase dehydrogenase reductase: repair RS05250 Tyr Arg Cys His Lys Asn Trp Pro Met Ile Leu Thr glu with reduced L- carrying a cysteine residues dehydratase: iolE phosphodiesterase: dipeptidase: tyr a tRNA arg a tRNA cys a tRNA his a tRNA lys a tRNA asn tRNA trp a tRNA pro a tRNA Met met initiator tRNA met ile a tRNA leu a tRNA thr a tRNA glu a tRNA lipoyl thiouridine(34) HPr kinase/ 5'-nucleotidase: protein tRNA a (2E)-but-2-enoyl-[acp] 3-oxoacyl-ACP transfer quinone 3D-(3,5/4)- 3-deoxy-D-glycero- uxaC glutamyltransferase: ggt octaprenyltransferase: tetrahydrofolate octaprenyltransferase: deacylase: thpR DusA: dusA pepQ kinase/ phbB FtsA glutamine-- val a tRNA Val cysteine residues disulfide bond in a protein synthase: synthase an [RNA]-3'- ABB29_RS06145 3-oxopentanoyl- MutS: mutS a (2E)-but-2-enoyl-[acp] reductase 2,5-hexodiulosonate ubiA synthase/ ubiA ABB29_RS09545 phosphorylase: 20 aspartate- tRNA ligase/ serine- alanine- glycine-- phenylalanine- trihydroxycyclohexane- gamma- ribunucleoside- a uracil in tRNA phosphatase: a properly RS00975 FabG: fabG D-fructuronate lipA MnmA: mnmA dihydrofolate ABB29_RS14405 guanosine CoA tyrosine-- arginine-- -tRNA YqeY domain cysteine-- histidine-- -tRNA lysine- asparagine- tryptophan-- proline-- methionine- methionine- -tRNA isoleucine- leucine-- threonine- glutamate- tRNA ligase: -tRNA ligase: enoyl-ACP 1,2-dione 2-dehydro- glutamyltransferase: ggt 2'-phosphate a phosphorylatedaceK matched enoyl-ACP synthase: folC 3-all trans- a [protein] (L-serine/L- a proteinogenic tRNA ligase: tRNA ligase: ligase: fusion protein: tRNA ligase: tRNA ligase: ligase: -tRNA -tRNA tRNA ligase: tRNA ligase: valine--tRNA ligase: -tRNA -tRNA ligase: -tRNA tRNA ligase: -tRNA -tRNA ABB29_RS13125 ABB29_RS11900 reductase: a (3R,11Z)-3-hydroxy- (2E)-oct-2-enoyl-CoA 3D-(3,5/4)- 3-deoxy-D- a [2-oxoglutarate 3-hexaprenyl-4- pro isocitrate DNA base pair reductase: an unsulfurated 34 Trp threonine) phosphate ABB29_RS15060 gluconate 5- 5'-deoxyadenosine met dehydrogenase a [SAMP] C- a 2-thiouridine hexaprenyl-4- D-tryptophan a tRNA amino acid BamE ABB29_RS00010 ABB29_RS00070 aspS ABB29_RS03050 ABB29_RS03610 ABB29_RS03675 serS ligase: lysS ligase: asnS ABB29_RS08795 ABB29_RS09220 ABB29_RS09245 ligase: metG ligase: metG alaS ligase: ileS ABB29_RS11575 ligase: thrS ligase: gltX glyQ pheS ABB29_RS15060 icos-11-enoyl-[acp] trihydroxycyclohexane- [sulfur carrier] hydroxybenzoate dehydrogenase RS09730 dehydrogenase E2 protein] N 6 hypoglycin B L-cysteinylglycine terminal glycine in tRNA aminobenzoate 3-hydroxyacyl- 1,2-dione acylhydrolase a (6S)-5- RS09580 an L-methionyl- a butanoyl-[acp] KduD: kduD -lipoyl-L-lysine an L-tyrosyl- an L-arginyl- an L-aspartyl- an L-glutaminyl- an L-cysteinyl- an L-histidyl- an L-seryl- an L-lysyl- an L-asparaginyl- an L-tryptophanyl- an L-prolyl- an L-valyl- an L-methionyl- an L-alanyl- an L-isoleucyl- an L-leucyl- an L-threonyl- an L-glutamyl- an L-phenylalanyl- a butanoyl-[acp] ACP dehydratase (decyclizing): iolD formyltetrahydrofolate RS12350 [elongator a glycyl-[tRNA Gly ] [tRNA Tyr ] [tRNA Arg ] [tRNA asp ] [tRNA Gln ] [tRNA Cys ] [tRNA His ] [tRNA ser ] [tRNA Lys ] [tRNA Asn ] [tRNA Trp ] [tRNA Pro ] [tRNA Val ] [initiator tRNA Met ] [tRNA Ala ] [tRNA Ile ] [tRNA Leu ] [tRNA Thr ] [tRNA Glu ] [tRNA Phe ] FabZ: fabZ (S)-3- 2-dehydro-3- Met beta-ketoacyl- 5-deoxy-D-glucuronate tRNA ] beta-ketoacyl- hydroxyoctanoyl-CoA deoxy-D-gluconate ACP synthase 3 β a (2E,11Z)-icosa- 3-phenyl-2- a [protein]- a DNA methyl all-trans- an N -methyladenine N-acetyl- -D- a phosphorylated (3R,5S)-3- a 2,3,4- a [protein]-L- ACP synthase II: fabF 5-deoxy- cob(II)inamide aci-nitroethane a holo [BryU acyl- a ribonucleoside FlgH 2,11-dienoyl-[acp] oxopropanoate tyr L-cysteine phosphotriester decaprenyl in DNA glucosaminyl-(1 Ins(2)P isocitrate hydroxy-1- saturated (3R)-3- methionine RS01515 II: fabF glucuronate ATP 4-hydroxybenzoate adenine carrier protein] 5'-monophosphate RS05380 enoyl-ACP diphosphate PRPP -> 4)-N-acetyl- 5'-nucleotidase: inositol dehydrogenasebifunctional pyrroline-5- hydroxyacyl-CoAacetoacetyl- peptide- a 3-oxohexanoyl-[acp] isomerase: iolB β ACP S- a 3-oxohexanoyl-[acp] reductase: DsbA family -D-muramate ABB29_RS06145 monophosphatase: isocitrate carboxylatepyrroline-5- CoA methionine Amino Acid Biosynthesis oxidoreductase: 3-oxooctanoyl-CoA 5-dehydro-2- KDGP aspartate/ methylated-DNA-- DNA-3- nitronate malonyltransferase: (S)-S-oxide 3-oxoacyl-ACP ABB29_RS15060 4-hydroxybenzoate 5'/3'-nucleotidase ABB29_RS06670 dehydrogenase carboxylate reductase: ABB29_RS02650 deoxy-D-gluconate cob(I)yrinic acid tyrosine/aromatic [protein]-cysteine S- adenine methyladenine monooxygenase: fabD reductase 3-oxoacyl-ACP reductase a [DsbB protein] a [DsbA protein] acetyl-CoA C- octaprenyltransferase: beta-N- a malonyl- SurE: surE inositol kinase/ reductase: phbB an electron- an intra- 5-dehydro-2- a,c-diamide aminotransferase: methyltransferase: phosphoribosyltransferase: glycosylase I: ABB29_RS15110 a 2,3,4-saturated MsrA: msrA RS09295 superpathway of L- superpathway of L-methionine L-tryptophan biosynthesis reductase FabG: fabG a gondoyl-[acp] carrying a with reduced L- acyltransferase: ubiA acetylhexosaminidase: [BryU acyl- a ribonucleoside monophosphatase: phosphatase: ABB29_RS08160 a protein-L- RS02565 L-histidine biosynthesis L-arginine superpathway of branched chain amino acid biosynthesis L-tyrosine L-arginine biosynthesis I (via L-ornithine) superpathway of L- L-cysteine biosynthesis I transfer quinol protein disulfide deoxygluconokinase: bifunctional adenosyltransferase: ABB29_RS09710 ABB29_RS14215 ABB29_RS06980 ABB29_RS10780 3-oxoacyl-CoA isoleucine biosynthesis I biosynthesis (transsulfuration) FabG: fabG disulfide bond cysteine residues ABB29_RS04750 nagZ carrier protein] ABB29_RS11695 aceK Hyp methionine- RS01820 degradation I biosynthesis I threonine biosynthesis 3-oxoacyl-ACP iolC 4-hydroxy-2- ABB29_RS02995 3-oxoacyl-ACP acetaldehyde nitrite an isocitrate (S)-S-oxide oxaloacetate PRPP (arginase pathway) pyruvate reductase oxoglutarate 3-(4- 3-decaprenyl-4- myo-inositol oxaloacetate thr glu gln ser reductase hexanoyl-CoA 5-dehydro-2-deoxy-D- a [protein]-S- an apurinic site N-acetyl-D- dehydrogenase aspartate/ chorismate oxaloacetate chorismate FabG: fabG aldolase/2- adenosylcobinamide hydroxyphenyl) phe [DNA] hydroxybenzoate 3-methyladenine GlcNAc arg FabG: fabG gluconate 6-phosphate triphosphate methyl-L-cysteine within DNA muramate tyrosine/aromatic ATP acetolactate chorismate aspartate/ dehydro-3-deoxy- pyruvate AMP aspartate/ threonine/serine a (3R)-3- CDP-diacylglycerol N 6 -L-threonylcarbamoyladenosine 37 RS01245 phosphoribosyltransferase: arginase: synthase: mutase: pheA tyrosine/aromatic a (3R)-3- phosphogluconate RS13255 aminotransferase: tyrosine/aromatic dehydratase: anthranilate hydroxyhexanoyl-[acp] biosynthesis II -modified tRNA biosynthesis ABB29_RS09710 ABB29_RS03695 rocF ABB29_RS12435 prephenate aminotransferase: synthase component hydroxyhexanoyl-[acp] Glycolysis aldolase: UgpC aminotransferase: ABB29_RS13090 ABB29_RS09710 3-hydroxyacyl- 1-(5-phospho- L-ornithine acetolactate I: ABB29_RS08945 3-hydroxyacyl- (2E)-hexenoyl-CoA ABB29_RS09955 asp ABB29_RS09710 prephenate N-acetyl-L- ACP dehydratase DHAP 2503 (1S,2R)-1- a cis-delta19- a [ribosomal β-D-ribosyl)-ATP synthase 2 threonine asp O-acetyl-L-serine thr DHAP 3-oxopropanoate adenine 2-amino-6-[1-hydroxyethyl]- a ferrocytochrome an isoprenoid a ferrocytochrome a peptide with a a holo [BryP acyl- a negatively histidinol dehydrogenase: glutamate hydrogen sulfide ACP dehydratase FabZ: fabZ glycolysis III (from glucose) palmitoyl-CoA 4-hydroxybenzoate ser C-(indol-3- stearoyl-CoA canavaninosuccinate Ins(1)P thr 37-methoxy-38- protein L3]- catalytic subunit: dehydratase: threonylcarbamoyl- D-glyceraldehyde in 23S rRNA 7-methyl-7,8-dihydropterin b diphosphate b leader sequence carrier protein] supercoiled DNA bifunctional bifunctional asp FabZ: fabZ 2-amino-4-hydroxy-6- 5 5 DNA L-glutamine ABB29_RS12440 ABB29_RS05095 acetylglutamate anthranilate PRPP AMP synthase: 3-phosphate pyruvate yl)glycerol inositol threonine/serine methyl-C57:1-[acp]cyclopropane histidinol aspartate kinase/ phosphoribosyl- ABB29_RS12430 bifunctional a (2E)-hex-2-enoyl-[acp] sn-glycerol hydroxymethyldihydropteridine ACP S- topoisomerase BamA (2Z)-2-aminobut- 3-(4- kinase: cysteine D-glucopyranose ABB29_RS09640 3-phosphate monophosphatase: dehydratase: fatty acyl dehydrogenase: GspD + + homoserine bifunctional aspartate aspartate kinase/ a (2E)-hex-2-enoyl-[acp] 3-phosphate (L-threonylcarbamoyl) (S)-3- 23S rRNA malonyltransferase: Na RS07090 Na AMP (S)-2-acetolactate hydroxyphenyl) synthase A: cysK diphosphokinase: 4-hydroxybenzoate signal argininosuccinate IV subunit A: parC ABB29_RS06670 phospholipid hisD dehydrogenase kinase/homoserine L-glutamate-5- 2-enoate ABB29_RS03640 homoserine anthranilate enoyl-ACP glucokinase: adenylate hydroxyhexanoyl-CoA (adenine(2503)-C(2) fabD ABB29_RS13090 cyclohydrolase/ pyruvate glycerol-3- acetyl-CoA ABB29_RS13740 octaprenyltransferase: tryptophan peptidase lyase: argH [+ 2 isozymes] synthase: cfa a [ribosomal I: thrA dehydrogenase I: thrA semialdehyde N-acetylglutamyl- dehydrogenase phosphoribosyltransferase: trpD enoyl-ACP reductase: ABB29_RS15340 )-methyltransferase a malonyl- inositol threonine phosphoribosyl- ketol-acid aspartate/ phosphate 1-O- tRNA (adenosine(37)-N6)- 2-amino-4-hydroxy-6- ubiA synthase: I: lepB a relaxed DNA a cis-methoxy- his protein L3]- phosphate I: thrA reductase: ABB29_RS15060 glucokinase: RlmN: rlmN [BryP acyl- monophosphatase: dehydratase: ATP diphosphatase bifunctional aspartate bifunctional reductoisomerase: tyrosine/aromatic cys threonylcarbamoyltransferase hydroxymethyldihydropteridine ABB29_RS10530 C59-meroacyl-[acp] 5 potassium- bifunctional ABB29_RS15060 acyltransferase carrier protein] ABB29_RS11695 ABB29_RS12440 N -methyl- HisIE: kinase/diaminopimelate proline ilvC aminotransferase: N-acetyl-gamma- bifunctional N-(5-phosphoribosyl)-anthranilate glk complex ATPase subunit diphosphokinase: folK trpB RS01545 K + transporting K + aspartate kinase/ a hexanoyl-[acp] PlsB: plsB a 4-hydroxy-3- L-canavanine fumarate L-glutamine Pal ABB29_RS03730 decarboxylase: dehydrogenase/L- (2R)-2,3- 2-iminobutanoate ABB29_RS09710 aspartate kinase/ superpathway of L- 2503 [1-(2-amino-7-methyl-4-oxo- palmitoleoyl-CoA a ferricytochrome a ferricytochrome oleoyl-CoA myo-inositol 2-oxobutanoate diaminopimelate glutamyl-phosphate a hexanoyl-[acp] a 1-acyl-sn D-glucopyranose type 1 TsaE: tsaE 3-oxohexanoyl-CoA a 2-methyladenine polyprenylbenzoate a leader sequence a peptide ATPase ABB29_RS14650 glutamate gamma- dihydroxy-3- diaminopimelate asparagine biosynthesis 5'-deoxyadenosine met 7,8-dihydro-3H-pteridin- b D-glyceraldehyde b decarboxylase: 1-(5-phospho-β- reductase: phosphoribosylanthranilate beta-ketoacyl- -glycerol 3- 6-phosphate [+ 2 isozymes] in 23S rRNA 5 5 semialdehyde methylbutanoate tyr decarboxylase: an N 6 -L- acetyl-CoA C- 6-yl)]ethyl diphosphate 3-phosphate trp ABB29_RS14650 D-ribosyl)-AMP ABB29_RS03650 isomerase: ABB29_RS10550 beta-ketoacyl- ACP synthase phosphate glucose-6- dehydrogenase dihydroxy-acid N-acetyl-L- ABB29_RS14650 asp threonylcarbamoyladenine 37 acetyltransferase: L-aspartyl-4-phosphate 1-(2-carboxyphenylamino)-1- ACP synthase II: fabF 1-acyl-sn-glycerol- phosphate RS08560 L-aspartyl- bifunctional PutA: putA dehydratase: glutamate 5- 3-phosphate in tRNA ABB29_RS00510 phosphoribosyl- 2-oxobutanoate L-aspartyl- deoxy-D-ribulose 5-phosphate II: fabF isomerase: pgi RS13795 4-phosphate ilvD semialdehyde acyltransferase: acetyl-CoA C- 10 an α-D- RNase III mRNA 527 RS01685 aspartate-semialdehyde 4-phosphate indole-3-glycerol a 3-oxooctanoyl-[acp] an N-terminal an L-phenylalanyl- an L-methionyl- an N - 4-nitrophenyl a guanine (3E)-5-chloro-2- hydrogen a [phospholipid]- long chain AMP glu acetylornithine asparagine asparagine a 3-oxooctanoyl-[acp] ABB29_RS00150 F6P acyltransferase: isobutanoate galactoside processing ala pimeloyl-CoA a PII protein A(H2) phenyl acetate 3',5'-ADP aspartate- dehydrogenase: 3-methyl-2- acetolactate arginyl-[protein] Phe [initiator tRNA Met ] formyltetrahydrofolate palmitate in 16S rRNA oxopent-3-enoate peroxide palmitoleate polyphosphate cyclohydrolase/ transaminase: hydrogencarbonate phosphate synthase synthase ABB29_RS04750 Carbohydrate Degradation [tRNA ] UTP semialdehyde ABB29_RS10565 oxobutanoate synthase: aspartate- 3-oxoacyl-ACP 1-acyl-sn-glycerol- substrate 16S rRNA 2-keto-4- cyclopropane 3'(2'),5'- phosphoribosyl- ABB29_RS07155 synthase TrpC: trpC (glutamine- B: asnB 3-oxoacyl-ACP N-end rule pathway I (prokaryotic) dehydrogenase: ABB29_RS12435 semialdehyde reductase 3-phosphate alpha- (guanine(527)-N(7) pentenoate fatty acyl polyphosphate bisphosphate ATP diphosphatase glutamine- (1S,2R)-1-C-(indol-3- hydrolyzing) [+ 2 isozymes] reductase butanoyl-CoA catalase/ PutP ABB29_RS10565 L-aspartate 4-semialdehyde 2-isopropylmalate acetolactate N-acetyl-L- dehydrogenase: FabG: fabG acyltransferase: leucyl/phenylalanyl- superpathway of glucose and xylose degradation leucyl/phenylalanyl- methionyl-tRNA acetate--CoA galactosidase: 8-amino-7- [protein-PII] arylesterase: )-methyltransferase hydratase: arylesterase: phospholipid kinase 2: ppk2 nucleotidase HisIE: hydrolyzing yl)glycerol 3-phosphate : asnB FabG: fabG β Entner-Doudoroff pathway I ribonuclease peroxidase synthase: ornithine ABB29_RS10565 3-oxoacyl-ACP ABB29_RS00600 -D-fructose 1,6- tRNA--protein formyltransferase: ligase: acs ABB29_RS01120 oxononanoate uridylyltransferase: ABB29_RS02640 7 RsmG: rsmG ABB29_RS12340 ABB29_RS02640 synthase: cfa CysQ: cysQ RS10165 L-aspartate 4- ABB29_RS03730 synthase 2 carbamoyl- tRNA--protein III: rnc an N - 5-chloro-4-hydroxy- HPI: katG a [phospholipid]-8- long chain RS05060 homoserine ABB29_RS12445 [+ 2 isozymes] 3-oxoacyl-ACP a 1,2-diacyl- bisphosphate D-glucopyranose transferase: 527 1-(5-phospho-β-D-ribosyl)- catalytic subunit: acetylornithine phosphate L-aspartate 4- tryptophan synthase: asn reductase transferase: D-glucopyranose ABB29_RS09595 synthase: bioF glnD methylguanine (2-hexylcyclopropyl) polyphosphate semialdehyde dehydrogenase: reductase sn-glycerol a [protein] 6-phosphate ABB29_RS05245 2-oxopentanoate AMP 5-[(5-phosphoribosylamino) val ABB29_RS12430 deacetylase: synthase: semialdehyde ABB29_RS10530 trpB FabG: fabG ABB29_RS05245 6-phosphate α-D- a non in 16S rRNA octanoate ABB29_RS08025 (2S)-2- 3-phosphate an N-terminal RNase III homoserine ABB29_RS03635 FabG: fabG fructose- N-terminal L- crotonyl-CoA glucose-6- an N-formyl- isobutanoyl-CoA diphosphate galactopyranose galactosylated 4-nitrophenol palmitate A H O acetate phenol methylideneamino]imidazole- (S)-2-aceto-2- carA carB homoserine asn a (3R)-3- arginyl-[protein] glucose-6- AMP an mRNA fragment (8S)-8-amino-7- 2 dehydrogenase: bifunctional aspartate isopropylmalate indole ser bisphosphate leucyl-L-arginine phosphate L-phenylalanyl-L- L-methionyl- a tetrahydrofolate galactose acceptor processing coenzyme A a uridylylated CrcB 4-carboxamide superpathway of L-homoserine hydroxybutanoate dehydrogenase: a (3R)-3- hydroxyoctanoyl-[acp] phosphate a tRNA Phe oxononanoate ABB29_RS08025 kinase/homoserine 3-isopropylmalate carbamoyl aldolase class I: dehydrogenase: arginyl-[protein] met product mRNA PII protein RS10370 1-(5-phosphoribosyl)-5- and L-methionine biosynthesis ketol-acid L-ornithine ABB29_RS08025 hydroxyoctanoyl-[acp] dehydrogenase: [initiator tRNA ] RS07050 bifunctional dehydrogenase I: thrA dehydratase: phosphate 3-hydroxyacyl- ABB29_RS07545 leucyl/phenylalanyl- zwf [(5- phosphoribosylamino) reductoisomerase: tryptophan synthase: 3-hydroxyacyl- a CDP- zwf aspartate kinase/ leuC leuD bifunctional ACP dehydratase tRNA--protein 6-phospho methylideneamino]imidazole-4- ilvC ABB29_RS10530 trpB ACP dehydratase diacylglycerol (S)-3- 6-phospho L-homoserine asp ornithine aspartate kinase/ FabZ: fabZ D-glucono- a Chi-site containing a RecA DNA 2030 966 a protein-L- homoserine carboxamide isomerase: hisA triose-phosphate transferase: hydroxybutanoyl-CoA an N-terminal an L-phenylalanyl- a single- a [DNA]-3'- adenine a guanine a (2E,4Z)-2,4- succinate a D-hexose pyridoxamine 2-isopropylmaleate (R)-2,3-dihydroxy- carbamoyltransferase: homoserine FabZ: fabZ a [protein] 1,5-lactone D-glucono- glycyl-glycine glutathione double stranded recombination coenzyme A a type IV prepilin a phenyl acetate methionine- dehydrogenase isomerase: an N-terminal ABB29_RS05245 L-lysyl-[protein] [tRNA Phe ] stranded RNA hydroxyl in 23S rRNA in 16S rRNA dienoyl-CoA semialdehyde 5'-phosphate RS06855 phosphoribulosylformimino- homoserine O- bifunctional aspartate 3-methylpentanoate ABB29_RS03620 dehydrogenase a (2E)-oct-2-enoyl-[acp] N-terminal L- 1,5-lactone DNA with a blunt end and repair protein 23S rRNA 16S rRNA NADPH-dependent NAD-dependent glucokinase: (R)-S-oxide I: thrA 3-isopropylmalate trp ABB29_RS10505 L-lysyl-[protein] 6-phosphogluconolactonase: pyridoxamine peptide- AICAR-phosphate succinyltransferase: kinase/homoserine dihydroxy-acid L-lysine biosynthesis I I: thrA a (2E)-oct-2-enoyl-[acp] D-glyceraldehyde leucyl-L-lysine 6-phosphogluconolactonase: (adenine(2030)-N(6) (guanine(966)-N(2) 2,4-dienoyl- succinate- glk RS15860 dehydratase: enoyl-ACP DHAP pgl 5'-phosphate methionine RS14085 ABB29_RS08015 dehydrogenase I: thrA dehydratase: L-arginine biosynthesis III 3-phosphate pgl leucyl/phenylalanyl- gamma- polyribonucleotide CoA pyrophosphatase: exodeoxyribonuclease )-methyltransferase )-methyltransferase CoA reductase: arylesterase: semialdehyde glucokinase: L-homoserine leuC leuD enoyl-ACP reductase: oxidase: pdxH (R)-S-oxide imidazole bifunctional aspartate ilvD asp L-citrulline (via N-acetyl-L-citrulline) L-homoserine type I acetoacetyl-CoA D-gluconate tRNA--protein glutamyltransferase: ggt exodeoxyribonuclease nucleotidyltransferase: pnp ABB29_RS11195 III: xth prepilin peptidase: RlmJ: RsmD: rsmD ABB29_RS14040 ABB29_RS02640 dehydrogenase: ABB29_RS15340 cys O-succinyl-L-homoserine reductase: ABB29_RS15060 D-gluconate an N 2 - reductase glycerol kinase/diaminopimelate (2R,3S)-3- (3S)-3-methyl-2- asp glyceraldehyde- 6-phosphate transferase: gamma- V: recD recB recC [+ 3 isozymes] ABB29_RS06850 ABB29_RS14905 a (2E)-2- ABB29_RS08310 D-hexose 6- homoserine kinase: ABB29_RS15060 acetyl-CoA C- 6-phosphate an N 6 - methylguanine 966 PLP MsrB: msrB phosphate decarboxylase: isopropylmalate oxopentanoate bifunctional aspartate glu homoserine kinase: 3-phosphate decarboxylating 6- ABB29_RS05245 glutamyltransferase: ggt enoyl-CoA phosphate a [protein]-L- CcsA ABB29_RS03425 argininosuccinate an octanoyl-[acp] acyltransferase: phosphogluconate methyladenine 2030 in 16S rRNA succinate synthase: ABB29_RS14650 3-isopropylmalate kinase/homoserine ABB29_RS03425 superpathway of L-serine dehydrogenase: phosphogluconate a double stranded DNA a nucleoside a single- a [DNA]-3'- a 2'- methionine RS10660 O-succinylhomoserine synthase: an octanoyl-[acp] ABB29_RS04750 dehydratase: 3',5'-ADP 4'-phosphopantetheine in 23S rRNA acetate a phenol RS08670 O-phospho- hisH hisF dehydrogenase: dehydrogenase I: thrA and glycine biosynthesis I gap dehydrogenase: gnd γ with a RecA protein diphosphate stranded RNA deoxyribonucleoside a cleaved type (thiol)-lyase: acetyl-CoA C- ABB29_RS09950 L-phenylalanyl- -L-glutamyl- hydroxyl a peptide leuB ABB29_RS03625 O-phospho- D-ribulose a tRNA Phe L-cysteinylglycine 5'-monophosphate IV prepilin L-homoserine ABB29_RS08020 L-aspartyl-4-phosphate bifunctional aspartate beta-ketoacyl- fatty acid elongation -- saturated L-lysyl-[protein] glycylglycine loaded 3' overhang (2S)-2-isopropyl- L-homoserine TCA cycle TCA cycle I (prokaryotic) acetyltransferase: threonine D-erythro-1- kinase/diaminopimelate 3-phospho-D-glycerate ACP synthase 13-DPG 5-phosphate KDGP AICAR cystathionine 3-oxosuccinate ile L-arginino- ABB29_RS00510 synthase: (imidazol-4- aspartate-semialdehyde decarboxylase: N-acetyl-L- threonine phosphoglycerate II: fabF SecA yl)-glycerol gamma-synthase: ABB29_RS14650 succinate glutamate synthase: dehydrogenase: serA an acetoacetyl-[acp] phosphoglycerate ribulose-phosphate ribose-5- thrC dehydrogenase: S-methyl-5-thio-α-D-ribose acetyl-CoA acetyl-CoA an N-terminal RNase R degradation a 3-O-acetylated an [amino-group carrier a guanine 46 a double-stranded a supercoiled UDP-N-acetyl- ABB29_RS09065 + an L-arginyl- (2E,6E)-farnesyl (S)-2- RS08040 3-phosphate ABB29_RS10565 L-aspartyl-4-phosphate argininosuccinate thrC 1-phosphate degradation I 3-phosphooxypyruvate a 3-oxodecanoyl-[acp] kinase: 3-epimerase: phosphate bifunctional meso-diaminopimelate α NAD(P)H a plastoquinone H 3-sulfo-L- rhamnogalacturonan I protoheme glu protein]-C-terminal-γ- α-D-muramate trp DNA with lesion a protein RS08200 acetylglutamate UDP-N-acetyl- -D-muramoyl- Arg substrate RNA diphosphate in tRNA oligonucleotide duplex DNA thr bifunctional lyase: argH ABB29_RS07525 ABB29_RS08935 isomerase 4-hydroxy-2- [tRNA ] aminobutanoate (L-glutamyl)-L-glutamate UDP-N- excinuclease 4-methyl-2- kinase: oxaloacetate citrate synthase: D-xylose L-alanyl-D-glutamate alanyl-[protein] tRNA UvrD-helicase tryptophan 7- histidinol- L-aspartate 4-semialdehyde thr phosphoserine 3-oxoacyl-ACP RpiA: rpiA oxoglutarate acetylglutamate oligoribonuclease: acetylmuramate ABC subunit L-cystathionine oxopentanoate aspartate-semialdehyde ABB29_RS03640 5-MTR-1-P 3-phospho-D-glycerate ABB29_RS07385 rhamnogalacturonan (guanosine(46)-N7) domain-containing halogenase: endopeptidase threonine/serine phosphatase/ dehydrogenase: arg transaminase: serC reductase xylose D-xylulose aldolase/2- NAD(P)H:quinone ribonuclease protoheme IX kinase: -methyltransferase orn protein: dehydrogenase: UvrA: uvrA N-acetylglutamyl- UDP-N-acetylmuramoyl- acetylesterase: glutamate-- ABB29_RS05785 La: lon dehydratase: imidazoleglycerol- homoserine ABB29_RS10565 S-methyl-5- FabG: fabG 2-methylcitrate Amine and Polyamine isomerase: 5-phosphate D-ribose 5- dehydro-3-deoxy- oxidoreductase: wrbA arginyltransferase: R: rnr farnesyltransferase: ABB29_RS03640 TrmB: trmB ABB29_RS13295 murB [+ 2 isozymes] RS07065 phosphate a 3-oxoacyl-[acp] 2,3-bisphosphoglycerate- L-alanyl-D-glutamate-- ABB29_RS08690 cysteine ligase: an [amino-group carrier an N 7 - a nucleoside 5'- UDP-N-acetyl-α- ABB29_RS13090 phosphate dehydrogenase: thioribose-1- O-phospho-L-serine 3-oxoacyl-ACP 3-oxoacyl- synthase: prpC Degradation xylA phosphate phosphogluconate NAD(P)H:quinone ABB29_RS08455 ABB29_RS13690 [+ 4 isozymes] DNA without RS03445 independent 2, 6-diaminopimelate ABB29_RS12975 protein]-C-terminal- methylguanine 46 monophosphate [+ 4 isozymes] D-glucosamine- 7-chloro-L- a peptide RS00400 dehydratase ABB29_RS08025 L-aspartate 4-semialdehyde N-acetyl-gamma- phosphate reductase ACP malate dehydrogenase: transketolase: tkt aldolase: oxidoreductase: wrbA a single lesion threonine phosphoglycerate N-acetylglucosamine D-xylulose ligase: ABB29_RS06775 a rhamnogalacturonan γ-(5-phospho-L- in tRNA enolpyruvate tryptophan HisB: hisB bifunctional aspartate leu glutamyl-phosphate isomerase: mtnA FabG: fabG reductase ABB29_RS13975 ABB29_RS09955 an N-terminal L- a nucleoside 5'- stranded DNA dehydratase: 3-(imidazol-4- L-homocysteine mutase: degradation II a diribonucleotide acetate type I γ-L-glutamyl-(S)- glutamyl)-L-glutamate kinase/homoserine 4-hydroxy- reductase: hydrogencarbonate FabG: fabG (S)-malate citrate D-sedoheptulose D-glyceraldehyde a tRNA Arg arginiyl-3-sulfo- monophosphate ferroheme o ABB29_RS12440 L-phenylalanine S-methyl-5-thio-D- a (3R)-3- ABB29_RS13605 xylulokinase: UDP-N-acetyl-α-D-muramoyl-L-alanyl- + yl)-2-oxopropyl dehydrogenase I: thrA tetrahydrodipicolinate ABB29_RS03650 N-acetyl-D- 7-phosphate 3-phosphate D-glyceraldehyde a plastoquinol NAD(P) L-alanyl-[protein] 2-aminobutanoate (2Z)-2-aminobut- biosynthesis I ribulose 1-phosphate hydroxydecanoyl-[acp] beta- 3-oxoacyl- xylB γ-D-glutamyl-meso-2,6-diaminopimelate RS02010 phosphate 5-methyltetrahydropteroyltriglutamate- synthase: ABB29_RS10775 N-acetyl-L- glutamine- 2-phospho-D-glycerate glucosamineN-acetylglucosamine 3-phosphate pyruvate 2-enoate methionine ser ketoacyl- ACP aconitate hydratase D-xylulose BtuB histidinol- - homocysteine S- L-homoserine (2S,4S)-4-hydroxy-2,3,4,5- glutamate 5- hydrolyzing methylthioribulose 3-hydroxyacyl- fumarate hydratase: kinase: RS05860 synthase: metH chorismate carbamoyl- 1-phosphate ACP reductase AcnA: acnA 5-phosphate transaldolase: type I phosphate methyltransferase: metE L-methionine biosynthesis III tetrahydrodipicolinate semialdehyde ACP dehydratase phosphopyruvate ABB29_RS10185 ABB29_RS01100 UDP-N-acetyl- decaprenyl-diphospho-N- ADP-L-glycero-β- heptosyl- an N-terminal p-nitrophenyl-α-D- a [release factor]- guanine 37 α-Kdo8N- chorismate serine FabG: fabG [+ 2 isozymes] N-acetyl-D- ABB29_RS03060 glyceraldehyde- α an L-arginyl- H + hydrogencarbonate a ribonucleoside a single stachyose roseoflavin an aldehyde an unfolded transaminase: methionine homoserine O- acetylornithine phosphate dehydratase: FabZ: fabZ synthase -D-glucosamine acetylmuramoyl-pentapeptide D-manno-heptose Kdo -lipid A 3-sulfino-L- galactopyranoside Phe D-ala (2->6)-lipid IV his 4-hydroxy- hydroxymethyltransferase: a (3R)-3- hydratase: eno class II fumarate hydratase: 3-phosphate 2 Arg triphosphate L-glutamine in tRNA A ABB29_RS03705 mutase: pheA transaminase: synthase: ABB29_RS03755 a 2,3,4-saturatedII: fabF glucosamine D-erythrose [tRNA ] stranded DNA 3-deoxy-D-manno- bifunctional protein synthase: metH succinyltransferase: tetrahydrodipicolinate ABB29_RS09410 hydroxyacyl-[acyl- ABB29_RS06265 F6P dehydrogenase: alanyl-[protein] peptide chain tRNA aldehyde 2-iminobutanoate ABB29_RS08015 L-homoserine prephenate ABB29_RS07155 carA carB a (2E)-dec-2-enoyl-[acp] fatty acyl-[acp] phosphoenolpyruvate fumarate cis-aconitate 6-phosphate 4-phosphate undecaprenyldiphospho- release factor (guanosine(37)-N1) D-alanine--D- octulosonic L-histidine N(alpha) riboflavin kinase/ dehydrogenase RS13005 L-histidinol reductase: ABB29_RS05105 5-(methylsulfanyl)-2,3- 3-hydroxyacyl-carrier protein] aconitate hydratase gap ADP-heptose--LPS carbonate alpha- alpha- chaperonin met N-acetylglucosamine- muramoylpentapeptide beta-N- N(5)-glutamine -methyltransferase alanine ligase: acid kinase: -methyltransferase: FAD synthetase: iron-sulfur RS05920 phosphate prephenate N-acetyl-L- carbamoyl dioxopentyl 1-phosphate gly ACP AcnA: acnA heptosyltransferase: dehydratase: galactosidase: DNA primase: galactosidase: GroEL: groL RS01135 cys O-succinyl-L-homoserine homoserine O- (S)-2,3,4,5-tetrahydrodipicolinate enoyl-ACP pyruvate 6-phosphate transketolase: tkt acetylglucosaminyltransferase: arginyltransferase: methyltransferase: TrmD: trmD ABB29_RS06805 ABB29_RS15120 egtD ABB29_RS11135 subunit: paoA dehydratase: ornithine phosphate dehydratase [+ 2 isozymes] 13-DPG ABB29_RS15115 can ABB29_RS01120 ABB29_RS13700 ABB29_RS01120 an N 1 - 4-O-phospho- bifunctional L-proline acetyltransferase: acireductone reductase: kinase: pyk deacetylase: nagA murG ABB29_RS08455 prmC D-alanyl-D-alanine roseoflavin pheA FabZ: fabZ methylguanine 37 α-Kdo8N- hercynine a carboxylate a protein histidinol- biosynthesis I ABB29_RS10275 2,3,4,5-tetrahydropyridine- synthase: mtnC ABB29_RS15060 D-glucosamine D-glyceraldehyde a [release factor]-N 5 5'-phosphate 2-oxobutanoate 3-phenyl-2- N-acetylornithine D-galactosamine and N- phosphoglycerate (heptosyl) - α-D- in tRNA Phe (2->6)-lipid IV phosphatase/ (from L-glutamate) O-succinylhomoserine 2,6-dicarboxylate N- 2-hydroxy-5- pyruvate 6-phosphate 3-phosphate 2 an N-terminal L- D-galactopyranose raffinose -methyl-L-glutamine A O-acetyl-L- oxopropanoate carbamoyltransferase: a decanoyl-[acyl-carrier protein] acetyl-D-galactosamine kinase: decaprenyl-pyrophosphoryl- Kdo -lipid A CO H O 4-nitrophenol ssDNA/pppN(pN) galactopyranose RS00180 imidazoleglycerol- (thiol)-lyase: succinyltransferase: dapD (methylsulfanyl)-3-oxopent- UDP ADP 2 Arg 2 2 acetolactate homoserine hydrogen sulfide succinate D-threo-isocitrate type I degradation ABB29_RS07525 a tRNA arginiyl-3-sulfino- hybrid phosphate ABB29_RS08020 aspartate/ ABB29_RS03620 ammonia assimilation cycle III (N-acetylglucosamine)-N- n -1 synthase: glu 1-enyl 1-phosphate isocitrate dehydrogenase glyceraldehyde- N-acetyl-D- L-alanyl-[protein] dehydratase N-succinyl-2-amino-6-ketopimelate tyrosine/aromatic beta-ketoacyl- a trans-2- 3-phospho- acetylmuramyl-(pentapeptide) glutamate 5- cystathionine acireductone enoyl-ACP α 3-phosphate galactosamine ABB29_RS12435 ACP synthase a 2,3,4-saturated enoyl-[acyl- ADP-forming succinate- (NADP(+)): icd -D-glucosamine D-glycerate HisB: hisB kinase: proB gamma-synthase: N-succinyldiaminopimelate aminotransferase: N-acetyl- synthase: mtnC ammonium reductase: dehydrogenase: 6-phosphate acetolactate γ II: fabF fatty acyl-[acp] carrier protein] -CoA ligase: sucC sucD 6-phosphate a [glycine-cleavage β an N-terminal L- (2Z)-2- 5-(methylsulfanyl) (3R)-3- -L-glutamyl ABB29_RS09065 aminotransferase: ABB29_RS09710 L-citrulline ABB29_RS15060 N-acetylglucosamine- UDP-N-acetyl-α-D-muramoyl-L- 3-aci- D-threo-7,8- an N-acetyl- - an adenine 34 synthase 2 histidinol 1,2-dihydroxy-5- gap nicotinate PRPP melibionate a [protein] (L-serine/L- 2-phosphoglycolate an aromatic 5-phosphate ABB29_RS07155 glu 6-phosphate a sulfurated [sulfur carrier] SAM complex H protein] alanyl-γ-D-glutamyl-meso-2,6- nitropropanoate dihydroneopterin D-hexosaminide alanyl-[S18 protein hydroxyhexa- -2,3-dioxopentyl in tRNA hydroxybutanoyl- RS00280 acetylornithine (methylsulfanyl) glutamine a 3-oxododecanoyl-[acp] 6 threonine) phosphate amino acid catalytic subunit: L-homocysteine phe 2-oxoglutarate N -octanoyl-L-lysine diaminopimeloyl-D-alanyl-D-alanine of 30S ribosome] 2,5-dienoate 1-phosphate tRNA CoA histidinol glutamate-5- deacetylase: pent-1-en-3-one glutamate synthetase: 13-DPG deacetylase: nagA 2-phospho- ribosomal protein protein phosphoglycolate 2-keto-4- aspartate/ acetoacetyl- ABB29_RS12430 L-cystathionine N-succinyl-L,L-2,6-diaminopimelate enoyl-ACP succinyl-CoA 2-oxoglutarate acireductone adenosine(34) dehydrogenase: semialdehyde ABB29_RS03635 acireductone synthase large ABB29_RS08350 3-oxoacyl-ACP F6P D-galactosamine D-glycerate nitronate nicotinate beta-N- alpha- S18-alanine N- phosphatase phosphatase: pentenoate tyrosine/aromatic CoA (S)-2-aceto-2- dehydrogenase: 5-methyltetrahydropteroyltriglutamate- reductase: phosphoglycerate dihydroneopterin acetylhexosaminidase: galactosidase: acetyltransferase: CheZ: ABB29_RS03555 synthase: mtnC deaminase hisD methionine dioxygenase: subunit: gltB [+ 2 isozymes] reductase 6-phosphate lipoyl penicillin-binding monooxygenase: phosphoribosyltransferase: hydratase: aminotransferase: reductase: hydroxybutanoate ABB29_RS03665 - homocysteine S- succinyl-diaminopimelate L-citrulline imidazole ABB29_RS15060 kinase: phosphopyruvate aldolase: folB nagZ ABB29_RS01120 rimI ABB29_RS04275 1,2-dihydroxy-5- TadA: tadA synthase: ABB29_RS03750 FabG: fabG Respiration synthase: lipA protein 2: mrdA ABB29_RS15110 pncB an N-terminal N-acetyl- glycolate ABB29_RS12340 ABB29_RS09710 a hypoxanthine phbB ketol-acid histidinal methyltransferase: metE desuccinylase: dapE glycerol ABB29_RS07525 hydratase: eno a [protein] Ser/Thr (S)-4-hydroxy- (methylsulfanyl) an aromatic L-glutamate-5- 4-(methylsulfanyl) 3-oxoacyl-ACP L-alanyl-[S18 protein 34 in tRNAs acetoacetyl-CoA HtpX reductoisomerase: metH methionine L-glutamate phosphate 2-oxohexanoate 2-oxo-acid semialdehyde argininosuccinate -2-oxobutanoate reductase 2-oxoglutarate 3-phospho- phosphoenol [unspecified 6-(hydroxymethyl) an N-acetyl-β- α-D- of 30S ribosome] pent-1-en-3-one ilvC histidinol synthase: L,L-diaminopimelate biosynthesis III ammoniumsynthase: gln 2-oxoglutarate decarboxylation to succinyl-CoA D-tagatofuranose a [glycine-cleavage UDP-N-acetylmuramoyl-L- glycolaldehyde an alcohol D-gluconate L-homocysteine synthase: FabG: fabG dehydrogenase D-glycerate pyruvate an unsulfurated 3-oxopropanoate nitrite degradation NaMN -7,8-dihydropterin D-hexosamine galactopyranose dehydrogenase: metH hisH hisF NADH repair (prokaryotes) 6-phosphate 5'-deoxyadenosine met complex H protein] N 6 D-ala alanyl-γ-D-glutamyl-meso-2,6- (R)-2,3-dihydroxy- ABB29_RS03625 CDP-diacylglycerol a [2-oxoglutarate E1 component: 2,3-bisphosphoglycerate- pyruvate [sulfur carrier] products] hisD L-alanine diaminopimelate epimerase: 2-oxoglutarate [+ 7 isozymes] a (3R)-3- fatty acid biosynthesis -[(R)-lipoyl]-L-lysine diaminopimeloyl-D-alanine 3-methylpentanoate 5-methyltetrahydropteroyltriglutamate- L-arginino- ABB29_RS06290 independent kinase: pyk glutamate hydroxydodecanoyl-[acp] biosynthesis I initiation (type II) dehydrogenase methionine met biosynthesis III ABB29_RS06475 6 NADH dihydroxy-acid his (S)-1-pyrroline- - homocysteine S- synthase large succinate E2 protein] N 2-oxoglutarate phosphoglycerate alanine synthase: metH 2-oxoglutaramate 3-hydroxyacyl- PstS dehydratase: 5-carboxylate methyltransferase: metE subunit: gltB met DHAP -lipoyl-L-lysine mutase: D-tagatofuranose pyruvate lysine within a 2-O-acetylated p-nitrophenyl- 2498 a [protein]- racemization meso-diaminopimelate argininosuccinate acetyl-CoA dehydrogenase a [pyruvate dehydrogenase E2 [DNA] S-(2-hydroxyacyl) raffinose a cytidine an insertion sequence (R)-3- a (2E,4E)-2,4- a [phospholipid]- ilvD cys glu ACP dehydratase 6 β L-tyrosine pyrroline-5- methionine glu lyase: argH acetyl-CoA carboxylase 2-oxoglutarate E1 component: ABB29_RS13605 1,6-bisphosphate a sulfurated [sulfur carrier] SAM protein] N -octanoyl-L-lysine gcv protein H an octanoyl-[acp] rhamnogalacturonan I -D-galactoside glutathione in 23S rRNA element IS30 hydroxybutanoate dienoyl-CoA asp oleate GTP cysteine FabZ: fabZ D-galactose degradation I (Leloir pathway) phosphate (3S)-3-methyl-2- carboxylate synthase: metH carboxyltransferase dehydrogenase ABB29_RS06290 2-phospho- 23S rRNA transposase: 3-hydroxybutyrate NADPH-dependent aspartate/ phosphotyrosine cyclopropane ala desulfurase: bifunctional aspartate sn-glycerol (cytidine(2498)-2'-O) 2,4-dienoyl- fatty acyl oxopentanoate reductase: arg subunit beta: E1 component: D-glycerate D-tagatose- β rhamnogalacturonan alpha- ABB29_RS12900 dehydrogenase: tyrosine/aromatic protein alanine ABB29_RS14575 kinase/diaminopimelate a (2E)-dodec-2-enoyl-[acp] 3-phosphate -D- lipoyl(octanoyl) exodeoxyribonuclease beta-glucosidase: hydroxyacylglutathione -methyltransferase CoA reductase: phospholipid ABB29_RS08160 met 2-oxoglutarate ABB29_RS10520 ABB29_RS06290 (R)-NADHX bisphosphate acetylesterase: galactosidase: [+ 5 isozymes] ABB29_RS10340 aminotransferase: phosphatase: racemase: ala decarboxylase: bifunctional phosphopyruvate galactopyranose transferase I: sbcB ABB29_RS09940 hydrolase: gloB RlmM: rlmM an insertion ABB29_RS14040 synthase: cfa enoyl-ACP glycerol-3- malonyl-CoA [+ 2 isozymes]a [2-oxoglutarate a [2-oxoglutarate aldolase, lipoyl synthase: lipA ABB29_RS08690 ABB29_RS01120 a 2-O- ABB29_RS09710 ABB29_RS12745 Cls alr ABB29_RS14650 ADP-dependent hydratase: eno aldose epimerase: LipB: lipB sequence IS30 with acetoacetate a (2E)-2- a [protein]- a [phospholipid]- pro reductase: phosphate 1-O- dehydrogenase dehydrogenase class II, non- methylcytidine 2498 oxaloacetate c-di-GMP D-ala NAD(P)H-hydrate ABB29_RS12850 integrated transposon enoyl-CoA L-tyrosine dihydrosterculate acyltransferase ACP S- 6 6 phosphoenol catalytic subunit: a 2'- α in 23S rRNA ile lys ABB29_RS15060 E2 protein] N E2 protein] N -S- α-D- a [glycine-cleavage a rhamnogalacturonan D-galactopyranose 4-nitrophenol a 2-hydroxy -D- PlsB: plsB malonyltransferase: fabD dehydratase/ pyruvate ABB29_RS01110 a [pyruvate dehydrogenase deoxyribonucleoside [DNA] acetate glutathione sucrose -dihydrolipoyl- succinyldihydrolipoyl- galactopyranose 5'-deoxyadenosine acyl-carrier protein complex H protein] type I carboxylate galactopyranose a 1-acyl-sn NAD(P)H-hydrate met 6 an unsulfurated [sulfur carrier] a dodecanoyl-[acp] L-lysine L-lysine pyruvate E2 protein] N -lipoyl-L-lysine N 6 -octanoyl-L-lysine 5'-monophosphate Nucleoside and Nucleotide Biosynthesis -glycerol 3- a malonyl-[acp] epimerase: kinase: pyk D-glyceraldehyde ABB29_RS10715 DHAP RS00875 phosphate (S)-NADHX 3-phosphate beta-ketoacyl- 1-acyl-sn-glycerol- ketoacyl-ACP synthase pyruvate α superpathway of pyrimidine 2-oxoglutarate -D-galactose α UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N α poly-3- (R)-S- a (1->4)- a cytidine 1402 (3R)-3- an adenosine 34 γ-glutamyl- Metabolic Regulator superpathway of guanosine superpathway of inosine-5'-phosphate biosynthesis I guanine and superpathway of pyrimidine deoxyribonucleoside salvage ACP synthase 3-phosphate III: ABB29_RS03140 bifunctional UDP- -D-glucose UDP-N-acetyl- -D-muramoyl- D-alanyl-D-alanine a lipid II maltohexaose oxaloacetate N-ethylmaleimide L-cysteate a dipeptide ribonucleotides de novo biosynthesis dehydrogenase 1-phosphate -acetylmuramoyl-L-alanyl-γ- γ hydroxyoctanoate lactoylglutathione α-D-glucan in 16S rRNA hydroxyoctadecanoyl- in [tRNA Arg2 ] isopropylamide Biosynthesis nucleotides de novo biosynthesis I adenosine nucleotides guanosine salvage II II: fabF acyltransferase: 3-oxoacyl-ACP synthase ADP-dependent L-alanyl- -D-glutamyl-L-lysine E1 component: D-glutamyl-L-lysyl- D-alanine 16S rRNA citrate synthase: aspartate/ membrane CoA tRNA ferredoxin- de novo biosynthesis I 2'-deoxycytidine laurate ABB29_RS00150 III: ABB29_RS00360 NAD(P)H-hydrate alkene reductase: acetoacetyl- ppGpp metabolism gln AIR ABB29_RS06290 lactose degradation II β undecaprenyldiphospho- (cytidine(1402)-2'-O) ABB29_RS07385 tyrosine/aromatic dipeptidase: adenosine(34) type protein hydrogencarbonate 1-acyl-sn-glycerol- dehydratase/ (1,4)- -D-xylan UDP-N-acetylmuramoyl- penicillin-binding alpha-glucosidase: alpha-glucosidase: ABB29_RS05450 CoA RS00945 IMP long-chain fatty muramoylpentapeptide beta-N- polyhydroxyalkanoate hydroxyacylglutathione -methyltransferase: 2-methylcitrate aminotransferase: ABB29_RS15375 deaminase NapF: napF IMP 5-(carboxyamino)imidazole guanosine nucleoside a 3-oxotetradecanoyl-[acp] 3-phosphate an acetoacetyl-[acp] dihydrolipoyllysine- NAD(P)H-hydrate degradation tripeptide--D-alanyl- protein 2: mrdA ABB29_RS03475 ABB29_RS03475 reductase: asp deaminase: acid--CoA ligase: (S)-lactate (R)-lactate α-lactose acetylglucosaminyltransferase: depolymerase: phaZ hydrolase: gloB a 2'-O- rsmI synthase: prpC ABB29_RS09710 phbB TadA: tadA N-(γ-L-glutamyl) pppGpp ribonucleotide synthase: acyltransferase: residue epimerase: UDP- D- alanine ligase: 1,2-dihydroxypropane- N-ethylsuccinimide a proteinogenic an inosine 34 glutamine- IMP ABB29_RS05180 a (1->4)-β-D-xylan murG 1402 3-sulfopyruvate 3-oxooctadecanoyl- ABB29_RS06440 dCMP 3-oxoacyl-ACP succinyltransferase: glucose 4- methylcytidine amino acid Arg2 -L-alaninol ABB29_RS12275 ABB29_RS00600 ABB29_RS10715 endo-1,4-beta- ABB29_RS06780 1,2,3-tricarboxylate CoA in [tRNA ] hydrolyzing dehydrogenase: nucleoside reductase a 1,2-diacyl- sucB epimerase a N-acetylglucosamine--N- a (1->4)- in 16S rRNA adenylosuccinate (d)CMP kinase: lauroyl-CoA xylanase: poly-3- poly-3- D-glucopyranose maltopentaose α D-glucopyranose bifunctional (p)ppGpp carbamoyl- guaB N5-CAIR guanine deaminase: FabG: fabG sn-glycerol NADH 3'-ketolactose GalE: galE ditrans,octacis-undecaprenyldiphospho- UDP D-ala acetylmuramyl-(tetrapeptide) (R)-lactate glutathione -D-glucan synthase: ABB29_RS04710 ABB29_RS12830 UDP-N-acetyl-α-D-muramoyl-L-alanyl- hydroxyoctanoate hydroxyoctanoate synthetase/guanosine- phosphate ABB29_RS03035 3-oxoacyl-ACP 3-phosphate a (1->4)-β-D-xylan N-acetyl-(N-acetylglucosaminyl)muramoyl- pyrophosphoryl-undecaprenol SugE ABB29_RS08610 beta-glucosidase: γ γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine 3',5'-bis(diphosphate) 3'- synthase: XMP 5-(carboxyamino)imidazole hypoxanthine-guanine dCDP reductase oligosaccharide L-alanyl- -D-glutamyl-L-lysyl-D-alanine Aromatic Compound Biosynthesis ABB29_RS09940 pyrophosphohydrolase: carA carB ribonucleotide mutase: purE phosphoribosyltransferase: 2'-deoxyuridine FabG: fabG 2-oxoisovalerate decarboxylation to isobutanoyl-CoA nucleoside- β ABB29_RS07285 glutamine- adenylo-succinate ABB29_RS03265 (Kdo) -lipid A 3-keto- -D- α-D- α undecaprenyl-diphospho-N-acetylmuramoyl-L- 1518 a 3,5,7,9,11,13,15- 1402 2 α UDP-N-acetyl- -D-glucosamine an [HPr]- phosphoenol 7,8-dihydrofolate + phosphoenol adenine / a cytidine a [protein]- phosphoenol chorismate biosynthesis I hydrolyzing GMP asp CAIR diphosphate a (3R)-3- a CDP- biosynthesis I (E. coli) an [apo BCAA galactose UDP- -D- γ NADPH H hydrogencarbonate uroporphyrinogen-III 3-oxopropanoate a double stranded DNA D-threo-isocitrate D-glyceraldehyde bifunctional (p)ppGpp 3-(4-hydroxyphenyl) carbamoyl thymidine kinase: stearate biosynthesis glucopyranose alanyl- -D-glutamyl-L-lysyl- D-alanyl-D-alanine L-histidine pyruvate monoglutamate pyruvate adenine 1519 in 16S rRNA hepta-oxo- in 16S rRNA thr L-glutamine pyruvate guanosine-5'- asp kinase: ndk hydroxytetradecanoyl-[acp] diacylglycerol dehydrogenase β galactose aldehyde synthetase/guanosine- phosphate synthase: guaA adenylosuccinate GMP ABB29_RS13305 II (bacteria and plants) α-Kdo-(2->4)- NADPH repair (prokaryotes) -D-xylopyranose 1-phosphate uroporphyrinogen-III C- 16S rRNA hexadecanoyl-[PKS-acp]aldo/keto 16S rRNA malonic DNA gyrase isocitrate chemoreceptor triphosphate,3'- pyruvate biosynthesis E2 protein] N 6 undecaprenyldiphospho- RS01330 3',5'-bis(diphosphate) 3'- D-erythrose lyase: purB dCTP 3-hydroxyacyl- α-Kdo-(2->6)- alpha-ketoacid methyltransferase: cobA (adenine(1518)-N(6)/ reductase: (cytosine(1402)-N(4) semialdehyde dehydrogenase L-threonine 3- glutamine pyruvate diphosphate phosphoribosylaminoimidazolesuccinocarboxamide thymidine -lipoyl-L-lysine phosphomannomutase/ muramoylpentapeptide beta-N- phosphoenolpyruvate- dihydrofolate subunit A: gyrA dehydrogenase: pyrophosphohydrolase: 4-phosphate GMP dUMP ACP dehydratase lipid IV (E.lauroyl coli) dehydrogenase phosphoenolpyruvate uroporphyrinogen-III adenine(1519)-N(6))- ABB29_RS04690 )-methyltransferase reductase: iron-sulfur dehydrogenase: deamidase kinase: pyk phosphatase: ppx 3-deoxy-7- aspartate synthase: ABB29_RS08925 a palmitoyl-[acp] A acetylglucosaminyltransferase: [+ 3 isozymes] ABB29_RS14975 tyr FabZ: fabZ dihydrolipoyl subunit beta: NADPH D-galactopyranose phosphoglucomutase: -protein reductase: carboxylase: ppc dimethyltransferase RsmH: rsmH ABB29_RS12575 subunit: paoA tdh CheD: cheD ABB29_RS01470 phosphoheptulonate carbamoyltransferase AMP beta-ketoacyl- acyltransferase: C-methyltransferase: [+ 3 isozymes] an N 4 - a negatively aspartate/ thymidine kinase: α dehydrogenase: ABB29_RS09120 murG phosphotransferase: ptsP ABB29_RS02955 9-hydroxy-3,5,7,11,13,15- 2-oxoglutarate a [protein]-α- pyruvate -Kdo-(2->4)ABB29_RS09550 ABB29_RS08835 ABB29_RS00500 RsmA: rsmA 1402 aminoacetone synthase: catalytic subunit: thymidylate ACP synthase D-mannose degradation N 6 -dimethyladenine 1518 methylcytidine 3-hydroxypropanoate supercoiled DNA D-glycerate tyrosine/aromatic guanylate SAICAR ABB29_RS13305 a (2E)-tetradec-2-enoyl-[acp] -α-Kdo-(2->6) lpdA hexaoxohexadecanoyl- L-glutamate ABB29_RS02065 ABB29_RS08195 synthase: II: fabF D-glucopyranose precorrin-2 6 1519 in 16S rRNA aminotransferase: kinase: gmk a 3-oxooctadecanoyl- dihydrolipoyl ditrans,octacis-undecaprenyldiphospho-N- an [HPr protein]- /N -dimethyladenine [PKS-acp] adenylate kinase: ABB29_RS02950 -(lauroyl)-lipid 6-phosphate UDP 5,6,7,8- + oxaloacetate GTP ppGpp 3-deoxy-7- 3-(4- D-mannopyranose π pyruvate NADP in 16S rRNA ABB29_RS09710 ABB29_RS07110 adenylosuccinate enoyl-ACP [acp] IV (E. coli) dehydrogenase: melibiose degradation acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L- N -phospho- tetrahydrofolate phosphoheptulonate hydroxyphenyl) A an [apo BCAA 6-phosphate N-carbamoyl- GDP lyase: purB reductase: 3-oxoacyl- myristoyl-acyl lpdA (R)-NADPHX mannose-1-phosphate alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine L-histidine synthase class II: pyruvate dehydrogenase an [apo BCAA dehydrogenase bifunctional L-aspartate 5-aminoimidazole ribonucleotide biosynthesis I ABB29_RS15060 ACP carrier protein- 6 guanylyltransferase/ bifunctional (p)ppGpp biotin-carboxyl carrier 6 E2 protein] N -S-[2- ADP-dependent melibiose 3-deoxy- ABB29_RS13945 ADP AICAR E2 protein] N mannose-6- synthetase/guanosine- dTMP reductase dependent methylpropanoyl]dihydrolipoyl- DNA combined with an [amino-group carrier protein]- 1939 nucleoside- dihydroorotase: a myristoyl-[acp] protein assembly -dihydrolipoyl- NAD(P)H-hydrate an N-terminal L- an L-arginyl- a uracil (2R,3S)-3- a phosphate 3',5'-bis(diphosphate) 3'- D-arabino- bifunctional FabG: fabG acyltransferase: L-lysine phosphate isomerase: dethiobiotin a sulfurated SAM a peptidoglycan exogenous DNA to form C-terminal-γ-(L-glutamate 5- maltoheptaose dihydrolipoamide a holo [PedN acyl- a folate wound RNA CAIR D-glucopyranose ABB29_RS03585 nucleoside- adenosylcobalamin- dTMP kinase: PRPP dehydratase/ aspartyl-[protein] Arg in 23S rRNA isopropylmalate diphosphate heptulosonate adenosylcobalamin- a [biotin carboxyl- ABB29_RS09550 L-lysine alpha-galactosidase: ABB29_RS09115 [sulfur carrier] [tRNA ] carrier protein] monoester pyrophosphohydrolase: diphosphate dependent phosphoribosylaminoimidazolecarboxamide ABB29_RS03180 beta-ketoacyl- 3-oxoacyl- NAD(P)H-hydrate a recombinational junction semialdehyde-2-yl)-L-glutamateN-acetyl-gamma- dihydrolipoyllysine- 23S rRNA dihydrofolate 3-isopropylmalate ATP-dependent 5-(carboxyamino) xylose kinase: ndk 7-phosphate dependent carrier protein]-L-lysine α-D-Kdo-(2->4) ABB29_RS01120 F6P Holliday junction ACP S- alkaline ABB29_RS07285 (S)-dihydroorotate kinase: ndk ribonucleoside- formyltransferase/IMP cyclohydrolase: purH ACP synthase ACP epimerase: glutamyl-phosphate residue (uracil(1939)-C(5)) reductase: dehydrogenase: RNA helicase imidazole isomerase: 3-dehydroquinate ribonucleoside- pyrimidine deoxyribonucleotides de novo biosynthesis I dTDP amidophosphoribosyltransferase: purF -α-D-Kdo-(2->6) resolvase RuvX: ruvX alpha-glucosidase: malonyltransferase: phosphatase: diphosphate II: fabF reductase bifunctional ABB29_RS10715 biotin arginyltransferase: reductase: acetyltransferase: -methyltransferase ABB29_RS02955 leuB RhlB: rhlB ribonucleotide xylA bifunctional (p)ppGpp synthase: diphosphate FAICAR -lipid A (E. coli) D-galactopyranose D-glucopyranose crossover junction ABB29_RS03475 fabD ABB29_RS15300 synthetase/guanosine- quinone-dependent reductase: UDP CTP nucleoside- β FabG: fabG biotin-- 2-oxo acid (S)-NADPHX synthase ABB29_RS08455 an [amino-group carrierABB29_RS03650 protein]- ABB29_RS02540 a malonyl[PedN RlmD: rlmD 4-methyl-2- [+ 2 isozymes] mutase: purE ABB29_RS08125 reductase: 5-phospho- - gly endodeoxyribonuclease a 5-methyluracil 1939 a 7,8-dihydrofolate keto-D-fructose dihydroorotate GTP ABB29_RS01930 bifunctional diphosphate a 3-oxohexadecanoyl-[acp] a (3R)-3- [acetyl-CoA- dehydrogenase BioB: bioB γ S-acetyldihydrolipoamide an unwound RNA an alcohol AIR 3',5'-bis(diphosphate) 3'- ABB29_RS01930 adenosylcobalamin- D-ribosylamine resolution of recombinationalRuvC: ruvC C-terminal- -(5-phospho- acyl-carrier in 23S rRNA oxopentanoate pyrophosphohydrolase: 3-dehydroquinate dehydrogenase: phosphoribosylaminoimidazolecarboxamide dependent kinase: ndk hydroxyoctadecanoyl- carboxylase] subunit E2: bifunctional an N-terminal N-acetyl-D- a N-acetylmuramoyl- L-glutamyl)-L-glutamate protein] ribonucleotide- ribonucleotide- CDP [acp] ligase/biotin ABB29_RS08825 ADP-dependent Amino Acid Degradation junction formation D-glucopyranose maltohexaose ABB29_RS01470 ABB29_RS03385 formyltransferase/IMP cyclohydrolase: purH ribonucleoside- dTTP 3-oxoacyl-ACP an unsulfurated Arg L-arginiyl-L- glucosamine pentapeptide- diphosphate diphosphate phosphoribosylamine- biotin 5'-deoxyadenosine met a tRNA of two intact strands type II 3- PRPP diphosphate reductase: reductase 3-hydroxyacyl- operon NAD(P)H-hydrate [sulfur carrier] aspartyl-[protein] diphosphoundecaprenol orotate reductase: reductase: adenosylcobalamin- -glycine ligase: purD L-leucine degradation I dehydroquinate ABB29_RS01930 FabG: fabG ACP repressor phosphatidylserine and dehydratase/ L-tyrosine degradation I L-alanine ABB29_RS13165 ABB29_RS13165 IMP dependent L-histidine degradation II L-proline degradation I GDP dehydratase: aroQ 3-oxoacyl-ACP dehydratase BirA: birA phosphatidylethanolamine NAD(P)H-hydrate degradation IV orotate ABB29_RS13175 ABB29_RS13175 ribonucleotide- ribonucleoside- GAR FabZ: fabZ a [biotin carboxyl- biosynthesis I epimerase: 10 N,N',N''- 1915 967 55 RNase G 3-dehydroshikimate phosphoribosyltransferase: diphosphate reductase: diphosphate reductase: guanine and reductase leu an N - an N-terminal L- an L-arginyl- β a pseudouridine a cytosine a uridine a monocarboxylic aldehydo-D- carrier protein]-N ABB29_RS10715 tyr pro phe a -D-galactoside triacetylchitotriose maltopentaose a holo [PedD acyl- a thiopurine a uridine in tRNA ethanol degradation pyrE ABB29_RS01930 phosphoribosylglycinamide FabG: fabG a (2E)-octadec- a CDP-diacylglycerol his ala formyltetrahydrofolate glutamyl-[protein] Arg in 23S rRNA in 16S rRNA in tRNA acid amide galacturonate dADP ABB29_RS13165 guanosine salvage 6 -biotinyl-L-lysine [tRNA ] carrier protein] shikimate 2-enoyl-[acp] aspartate/ bifunctional 23S rRNA 16S rRNA tRNA thiopurine S- tRNA catalase: substrate mRNA glucuronate dGDP ABB29_RS13175 ribonucleotide- formyltransferase: a (3R)-3- NADPH alanine ACP S- amidase: dehydrogenase: dUDP ABB29_RS14470 enoyl-ACP 4-methyl-2- tyrosine/aromatic proline beta-N- (pseudouridine(1915)- (cytosine(967)-C(5) pseudouridine(55) methyltransferase: dihydrouridine ABB29_RS05730 ribonuclease isomerase: orotidine 5'- nucleoside- diphosphate reductase: hydroxyhexadecanoyl-[acp] dehydrogenase: ald phenylalanine 4- beta-glucosidase: alpha-glucosidase: malonyltransferase: ABB29_RS13950 aroE guanosine reductase: a 3-sn-phosphatidyl- oxopentanoate urocanate aminotransferase: dehydrogenase/L- arginyltransferase: acetylhexosaminidase: N(3))-methyltransferase )-methyltransferase synthase TruB: truB ABB29_RS11315 synthase [+ 2 isozymes] G: rng uxaC phosphate nucleoside- diphosphate nucleoside- ABB29_RS13165 3-hydroxyacyl- 3-(4- pyruvate monooxygenase: ABB29_RS09940 ABB29_RS03475 fabD superpathway of pyrimidine FGAR a [biotin carboxyl- L-serine ABB29_RS09710 glutamate gamma- 3 RlmH: rlmH RsmB: rsmB 55 DusB: dusB ABB29_RS15060 ABB29_RS08455 nagZ an N - 967 a malonyl- a pseudouridine a thiopurine D-tagaturonate shikimate diphosphate kinase: ndk nucleobases salvage diphosphate kinase: ndk ABB29_RS13175 ACP dehydratase hydroxyphenyl) ABB29_RS00815 a 5-methylcytosine a monocarboxylate a 5,6-dihydrouridine acetaldehyde orotidine-5'- carrier-protein dimer]- phosphatidylserine urocanate semialdehyde methylpseudouridine 1915 [PedD acyl- in tRNA S-methylether an mRNA fragment kinase: ndk phosphoribosylformylglycinamidine FabZ: fabZ 6 pyruvate in 16S rRNA in tRNA phosphate uracil dUTP dCDP a stearoyl-[acp] N -biotinyl-L-lysine decarboxylase: psd hydratase: dehydrogenase an N-terminal a non galactosylated N,N'- N-acetyl-D- in 23S rRNA carrier protein] shikimate kinase: 10 D-galactopyranose D-glucopyranose maltotetraose decarboxylase: dATP guanine synthase: purL acetyl-CoA acetyl-CoA 3-methylbutanoyl- ABB29_RS14235 4-hydroxyphenylpyruvate PutA: putA 4a-hydroxy-N - Arg ABB29_RS08130 uracil nucleoside triphosphate nucleoside- a (2E)-hexadec-2-enoyl-[acp] an L-1- (S)-1-pyrroline- a tRNA L-arginiyl-L- galactose acceptor diacetylchitobiose glucosamine pyrF dGTP carboxylase carboxylase CoA dioxygenase: hppD formyltetrahydrofolate tyr phosphoribosyltransferase: upp pyrophosphohydrolase: diphosphate kinase: ndk phosphatidylethanolamine 4-imidazolone- 5-carboxylate glutamyl-[protein] shikimate 3- hypoxanthine-guanine FGAM carboxyltransferase biotin UMP UMP mazG enoyl-ACP 5-propanoate phosphate dCTP phosphoribosyltransferase: subunit beta: carboxylase homogentisate UMP kinase: phosphoribosylformylglycinamidine reductase: imidazolonepropionase: UMP kinase: dUTP diphosphatase: dut ABB29_RS03265 ABB29_RS10520 subunit: accC GDP-α-D- 3-phosphoshikimate 1- ABB29_RS11390 cyclo-ligase: ABB29_RS14475 ABB29_RS15060 stearate 3-methylcrotonyl- ABB29_RS14195 homogentisate 3-methyl-2- 5,10-methylene- 5-amino-4- β an [amino-group carrier protein]-C- a 5' triphospho- (2R,3S)-3- ABB29_RS11390 dUMP a [carboxyl-carrier PRPP a sialyloligosaccharide a 1,4- -D-glucan maltotriose [DNA] 4-guanidinobutyramide coniferaldehyde ethylphosphate propionamide mannose carboxyvinyltransferase: CoA 1,2-dioxygenase: L-glutamate-5- oxobutanoate tetrahydromethanopterin imidazolecarboxyamide terminal-γ-(L-ornithyl)-L-glutamate [mRNA] isopropylmalate CMP UDP GMP long-chain fatty protein dimer]-N 6 - DNA polymerase GDP- aroA UDP thymidylate synthase: AIR a palmitoyl-[acp] N-formimino- ABB29_RS08870 semialdehyde acetylornithine RNA coniferyl aldehyde 3-isopropylmalate alkaline 5-enolpyruvoyl- phosphorylation acid--CoA ligase: carboxybiotinyl-L-lysine acetyl/propionyl/ L-glutamate III subunit amidase: amidase: mannose 4,6- nucleoside- ABB29_RS02950 4-maleyl- 3-methyl-2-oxobutanoate adenine exo 1,3/1,4-beta-D- transaminase: pyrophosphohydrolase: dehydrogenase: dehydratase: phosphatase: shikimate 3- nucleoside- ABB29_RS05180 cyclopropane methylcrotonyl- bifunctional exo-alpha-sialidase: alpha-glucosidase: gamma/tau: dnaX ABB29_RS13950 ABB29_RS13950 dehydratase: CMP diphosphate kinase: ndk dTMP formimidoylglutamate acetoacetate hydroxymethyltransferase: phosphoribosyltransferase: glucan glucohydrolase: ABB29_RS07155 ABB29_RS02265 ABB29_RS13570 leuC leuD ABB29_RS15300 phosphate diphosphate fatty acid (CFA) CoA carboxylase proline ABB29_RS03345 an [amino-group carrier protein]- ABB29_RS03475 [+ 3 isozymes] gmd (d)CMP kinase: UTP stearoyl-CoA deiminase: panB ABB29_RS06980 ABB29_RS11830 a 5'-phospho- (2S)-2- GDP-4-dehydro- chorismate kinase: ndk dTMP kinase: biosynthesis subunit alpha: maleylacetoacetate dehydrogenase/L- C-terminal-γ-(L-glutamate 5- a 2'-deoxyribonucleoside 4-guanidinobutanoate ferulate ethanol propanoate gln ABB29_RS04710 a [phospholipid] cis ABB29_RS14205 [mRNA] isopropylmalate α-D-rhamnose synthase: CTP synthase: ABB29_RS03180 ABB29_RS03825 isomerase: maiA glutamate gamma- semialdehyde-2-yl)-L-glutamate 5'-monophosphate UTP CDP palmitate -olefinic fatty acid aroC ABB29_RS15225 cyclopropane methylcrotonoyl- N-formyl- semialdehyde N-acetylneuraminate an oligosaccharide a 1,4-β-D-glucan D-glucopyranose D-glucopyranose maltose nucleoside- dTDP 4-fumaryl- 2-dehydropantoate THMPT AICAR CTP synthase: long-chain fatty fatty acyl CoA carboxylase: L-glutamate dehydrogenase diphosphate CTP acetoacetate chorismate ABB29_RS15225 nucleoside- acid--CoA ligase: phospholipid ABB29_RS03865 N-formylglutamate PutA: putA kinase: ndk diphosphate kinase: ndk ABB29_RS05180 synthase: cfa amidohydrolase: a [phospholipid] 3-methylglutaconyl- XLLG xyloglucan glu a generic 38-40 2-hydroxychromene- a 23S rRNA (3R,7Z,10Z,13Z,16Z)-3- (6R)-L-erythro-5,6,7,8- CTP CTP dTTP fatty acid containing CoA ABB29_RS05325 seleno-L- a uridine in tRNA uroporphyrinogen-I maltose D-glycerate a glycogen DHAP Fe 2+ palmitoyl-CoA polynucleotide substrate oligosaccharide 2-carboxylate uridine 1911/1915/1917 hydroxydocosatetraenoyl-CoA tetrahydrobiopterin cyclopropane N-formylglutamate homocysteine fumarate RluA family pseudouridine 2-hydroxychromene- 23S rRNA uroporphyrinogen pteridine D-glycerate glycogen- methylglyoxal deformylase: hutG L-serine degradation 5-methyltetrahydropteroyltriglutamate- alpha-glucosidase: bacterioferritin: bfr synthase: ABB29_RS04620 2-carboxylate pseudouridine(1911/ acetoacetyl-CoA decarboxylase: reductase: dehydrogenase: debranching synthase: - homocysteine S- beta-glucosidase: ABB29_RS03475 S1/P1 nuclease: tRNA pseudouridine(38- isomerase: 1915/1917) reductase: phbB ABB29_RS08115 ABB29_RS13745 ABB29_RS10570 protein: ABB29_RS00650 [+ 2 isozymes] HMG-CoA glu glycine cleavage methyltransferase: metE ABB29_RS09940 ABB29_RS02825 ser ABB29_RS07505 40) synthase TruA: truA ABB29_RS07860 synthase RluD: rluD (7Z,10Z,13Z,16Z)-3- trans-O- a pseudouridine 1911/ D-glucopyranose 3+ a [glycine-cleavage 38-40 coproporphyrinogen I L-erythro-biopterin hydroxypyruvate a maltodextrin methylglyoxal Fe hydroxymethylglutaryl- threonine/serine SeMet a pseudouridine in tRNA oxodocosatetraenoyl-CoA complex H protein] N 6 hydroxybenzylidenepyruvate 1915/1917 in 23S rRNA CoA lyase: dehydratase: XXXG xyloglucan -[(R)-lipoyl]-L-lysine glycine cleavage system D-galactopyranose ABB29_RS03820 ABB29_RS13090 a 5'-phosphomononucleotide a 5'-phosphooligonucleotide oligosaccharide aminomethyltransferase aminomethyl- L-serine acetoacetate transferring GcvT: gcvT ammonia-lyase: 6 [+ 3 isozymes] 2,5-diamino-6-(5- an N -L- 10 glycine ABB29_RS08080 4a-hydroxy-N - XLXG xyloglucan a double (9Z,12Z,15Z,18Z,21Z)-3- β-D-glucopyranose CTP 2-aminoprop- 37 2-hydroxyisobutyramide a cytosine in DNA starch D-glycerate MeOH pyrazinamide L-methionine degradation dehydrogenase: phospho-D-ribitylamino) threonylcarbamoyladenine formyltetrahydrofolate oligosaccharide stranded DNA oxotetracosapentaenoyl-CoA 1-phosphate 2-enoate I (to L-homocysteine) gcvP pyrimidin-4(3H)-one in tRNA 4a-hydroxytetrahydrobiopterin beta- DNA (cytosine-5-)- cyclomaltodextrin D-glycerate catalase: dCTP deaminase: a [glycine-cleavage bifunctional tRNA exodeoxyribonuclease acetoacetyl-CoA amidase: amidase: [+ 5 isozymes]a [glycine-cleavage diaminohydroxyphosphoribosylaminopyrimidine dehydratase: phosphoglucomutase: methyltransferase: glucanotransferase: dehydrogenase: ABB29_RS05730 ABB29_RS10650 complex H protein] N 6 - threonylcarbamoyladenosine beta-glucosidase: V: recD recB recC reductase: phbB ABB29_RS13950 ABB29_RS13950 complex H protein] N 6 ABB29_RS04630 pgmB dcm ABB29_RS03465 ABB29_RS10570 [+ 2 isozymes] met aminomethyldihydrolipoyl- deaminase/5-amino-6-(5-phosphoribosylamino) dehydratase: ABB29_RS10140 ABB29_RS09940 UTP methionine -dihydrolipoyl-L-lysine uracil reductase RibD: ribD a cyclic N 6 -L- an N 10 -formyl- (3R,9Z,12Z,15Z,18Z,21Z)-3- β-D-glucose 2-hydroxy-2- a 5-methylcytosine a cyclodextrin pyrazine-2- L-lysine 2-iminopropanoate a 5'-phosphooligonucleotide hydroxypyruvate formaldehyde adenosyltransferase: 5-amino-6-(5-phospho- threonylcarbamoyladenosine 7,8-dihydrofolate hydroxytetracosapentaenoyl-CoA 6-phosphate methylpropanoate in DNA carboxylate D-ribitylamino)uracil 37 in tRNA XXXG xyloglucan ABB29_RS07775 D-galactopyranose SAM oligosaccharide L-threonine aminomethyl- L-glutamine degradation II transferring UDP-N-acetyl- degradation I pyruvate a 5-carboxymethylaminomethyluridine 34 XXLG xyloglucan 3-phenyl-2- (9Z,12Z,15Z,18Z)-3- N,N'- a uridine 13 cytidine a (1->4)- dCTP glycine a cytidine 34 in tRNA α-D-glucosamine NaMN D-ribofuranose acetamide in tRNA Leu oligosaccharide oxopropanoate oxotetracosatetraenoyl-CoA diacetylchitobiose in tRNA α-D-glucan dehydrogenase: nucleoside deaminase: thr tRNA (uridine(34)/cytosine(34)/5- tRNA (uridine(34)/cytosine(34)/5- UDP-N-acetylglucosamine beta-N- tRNA cyclomaltodextrin dCTP deaminase: gcvP gln 4-hydroxyphenylpyruvate acetoacetyl-CoA ABB29_RS06440 5'-nucleotidase: ribokinase: amidase: SAH L-threonine 3- carboxymethylaminomethyluridine(34) carboxymethylaminomethyluridine(34) 1-carboxyvinyltransferase: acetylhexosaminidase: pseudouridine(13) glucanotransferase: ABB29_RS10650 imidazole beta-glucosidase: dioxygenase: hppD reductase: phbB nucleoside deaminase: ABB29_RS06145 ABB29_RS07815 ABB29_RS13950 dehydrogenase: [+ 3 isozymes] -2'-O)- methyltransferase TrmL: trmL -2'-O)- methyltransferase TrmL: trmL murA nagZ synthase TruD: truD ABB29_RS03465 tdh glycerol L-aspartate UDP-N-acetyl-α-D- ABB29_RS09940 N-acetyl-D- ABB29_RS03035 dUTP a 5-carboxymethylaminomethyl- a 2'-O-methylcytidine 34 (2-hydroxyphenyl) (3R,9Z,12Z,15Z,18Z)-3- a pseudouridine 13 β-D- D-ribofuranose adenosylhomocysteinase: L-2-amino-3- phosphate degradation I glucosamine-enolpyruvate uridine a cyclodextrin acetate 34 Leu glucosamine 5-phosphate ABB29_RS07760 oxobutanoate synthase: 2'-O-methyluridine in tRNA in tRNA acetate hydroxytetracosatetraenoyl-CoA in tRNA ribosylnicotinate XXXG xyloglucan hisH hisF D-galactopyranose L-homocysteine glycine C- asp oligosaccharide acetyltransferase: kbl [+ 7 isozymes] aspartate/ glu tyrosine/aromatic gly aminotransferase: ABB29_RS09710 L-phenylalanine oxaloacetate L-glutamine L-glutamate degradation degradation II degradation I I (aerobic) L-asparagine degradation I phe gln glu glutamate phenylalanine 4- NAD-glutamate asn synthase large monooxygenase: dehydrogenase: asparaginase: subunit: gltB ABB29_RS00815 glu ABB29_RS06160 tyr ABB29_RS15660 2-oxoglutarate asp

a reduced plastocyanin an oxidized plastocyanin a polyamine

cytochrome RS08905 RS00860 RS00505 FlhB RS07395 RS15305 FtsL LolD LapB SecF RS08275 RS11605 ZipA RS12255 FliG FliO FliJ RS04265 RS06345 RodA RS14870 RS06175 RS03950 RS01360 RS09155 RS13180 PotA RS01185 RS06770 MsbA LptF RseP RS01430 RS02630 BetT RS06620 FliR FliM RS13660 TolQ MsrQ RS04575 AqpZ RS09975 RS01750 FtsB RS06810 RS07130 RS07650 RS00325 PstA RS08850 FeoB c oxidase

a polyamine O 2 H O 2 This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.