Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_001591825Cyc: Bacillus vietnamensis NBRC 101237 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari sn-glycerol phosphate phosphate pro phosphate phosphate phosphate thiamine molybdate D-xylose D-ribose 3-phosphate D-mannitol

L-cystine L-djenkolate lanthionine α,β-trehalose phosphate phosphate [+ 3 more] α,α-trehalose predicted predicted ABC ABC FliY ThiT XylF RbsB RS10935 UgpC TreP PutP RS10200 PstB PstB RS10385 RS03335 RS20030 RS19075 transporter transporter of molybdate of phosphate

α,β-trehalose 6-phosphate L-cystine D-xylose D-ribose sn-glycerol D-mannitol phosphate phosphate thiamine glutathione α α phosphate phosphate phosphate phosphate L-djenkolate 3-phosphate , -trehalose 6-phosphate pro 1-phosphate lanthionine molybdate phosphate [+ 3 more]

Metabolic Regulator Degradation Amine and Polyamine Macromolecule Modification tRNA-uridine 2-thiolation Degradation ATP biosynthesis a mature peptidoglycan a nascent β an N-terminal- an N-terminal- a peptide with DNA combined and selenation () L- degradation I -D-fructofuranose D-sedoheptulose [2Fe-2S] iron-sulfur , Carrier, and Vitamin Biosynthesis L- degradation V (meso-diaminopimelate adenosylcobinamide a peptidoglycan KDGP adenosylcobinamide L-methionyl-L- NMN L-methionyl-L- an N-terminal with exogenous superpathway of menaquinol-7 biosynthesis adenosylcobinamide-GDP adenosylcobinamide-GDP superpathway of coenzyme A biosynthesis I (bacteria) thiamine flavin biosynthesis I (bacteria and ) menaquinol-9 biosynthesis ppGpp L- degradation I L- L-arginine degradation L-arginine 4-aminobutanoate 1-phosphate 1,7-bisphosphate cluster biosynthesis molybdenum Aromatic Compound Biosynthesis ( pathway) containing) ribonucleoside (meso-DAP bifunctional threonyl-[] bifunctional seryl-[protein] L- DNA to form a salvage from cobinamide I salvage from cobinamide II diphosphate ADP degradation I XIII (reductive degradation degradation I cofactor biosynthesis cys 5'-triphosphate containing) adenosylcobinamide metallophosphatase/ recombinational 3-methyl-2- a 5,10- salvage III F0F1 ATP synthase: val Stickland reaction) III (arginine Holliday chorismate demethylmenaquinol-9 pppGpp chorismate biosynthesis I ile bifunctional / fructose 5'-nucleotidase: fructose junction L- desulfurase cob(II)inamide cob(II)inamide oxobutanoate methylenetetrahydrofolate GTP dipicolinate biosynthesis BVI01S_RS01215 arg thr decarboxylase/ 4-aminobutanoate bifunctional lytic type I methionyl type I methionyl type I methionyl junction thiamine demethylmenaquinone molybdate cysteine arg bifunctional adenosylcobinamide- bisphosphate BVI01S_RS05000 bisphosphate serine isochorismate cob(I)yrinic acid bifunctional (p)ppGpp atpB atpE atpF branched-chain- threonine pathway) transglycosylase/ bifunctional lytic 4-hydroxy-2- aminopeptidase: aminopeptidase: aminopeptidase: resolvase RS09595 cysteine cob(I)yrinic acid thiamine methyltransferase: D-erythrose desulfurase: branched-chain- arg adenosylcobinamide phosphate aldolase: aldolase: thr thr synthase: a,c-diamide 3-methyl-2-oxobutanoate predicted synthetase/guanosine- BVI01S_RS01235 amino-acid arginine deiminase: ammonia- arginine deiminase: C40 family transglycosylase/ oxoglutarate map bifunctional map map RuvX: ruvX desulfurase: diphosphokinase: BVI01S_RS08450 molybdopterin guanosine 3'- 4-phosphate BVI01S_RS13985 amino-acid kinase/ : BVI01S_RS13780 BVI01S_RS13780 a,c-diamide hydroxymethyltransferase: bifunctional ABC 3',5'-bis(diphosphate) 3'- bifunctional 3-deoxy-7- asp atpA BVI01S_RS01245 transaminase: ilvE : ilvA BVI01S_RS07215 succinate peptidase: C40 family aldolase/2- metallophosphatase/ BVI01S_RS14885 adenosyltransferase: BVI01S_RS07650 menaquinol-9 diphosphate 5'- [+ 3 ] transaminase: BVI01S_RS07215 (2Z)-2-aminobut- adenosylcobinamide- type I methionyl type I methionyl type I methionyl Holliday BVI01S_RS13985 adenosyltransferase: panB 3,4-dihydroxy- phosphoheptulonate : atpD BVI01S_RS01255 semialdehyde peptidase: dehydro-3-deoxy- BVI01S_RS08710 fructose- 5'-nucleotidase: fructose- BVI01S_RS15385 thiamine transporter pyrophosphohydrolase: triphosphate 3'- an [L-cysteine 3-methyl-2-oxobutanoate 2-enoate L-citrulline BVI01S_RS12875 phosphate aminopeptidase: aminopeptidase: aminopeptidase: junction serine serine [+ 3 isozymes] isochorismate BVI01S_RS15385 2-butanone- synthase/ BVI01S_RS11555 ilvE NAD-dependent phosphogluconate bisphosphate BVI01S_RS20420 bisphosphate RS09600 cob(I)yrinic acid superpathway of tetrahydrofolate biosynthesis diphosphate of molybdate: BVI01S_RS19350 diphosphatase: desulfurase]-S- ATP synthase subunit L-citrulline [+ 3 isozymes] guanylyltransferase: BVI01S_RS12875 bifunctional map 1-(β-D map map resolution resolvaseof thr thr cob(I)yrinic acid asp 4-phosphate chorismate mutase: [+ 3 isozymes] (3S)-3-methyl-2- ornithine succinate- aldolase: aldolase: aldolase: an S-sulfanyl-[L- a,c-diamide modB modA BVI01S_RS19350 sulfanyl-L-cysteine B: BVI01S_RS09665 BVI01S_RS08695 [+ 3 isozymes] adenosylcobinamide ribofuranosyl) recombinationalRecU: recU 2-succinyl-6- a,c-diamide 2-dehydropantoate synthase/GTP molybdopterin BVI01S_RS21200 oxopentanoate carbamoyltransferase: agmatinase: semialdehyde BVI01S_RS00415 BVI01S_RS15835 BVI01S_RS15835 cysteine desulfurase] adenosyltransferase: 3-deoxy- L-aspartyl-4-phosphate kinase/ hydroxy-2, 4- aspartate 1- cyclohydrolase II: adenine speB a mature peptidoglycan a mature peptidoglycan an N-terminal L- nicotinamide an N-terminal junction BVI01S_RS08690 adenosyltransferase: 2-dehydropantoate molybdate ATP ornithine argF dehydrogenase: bifunctional adenosylcobinamide- scaffold protein cyclohexadiene- [corrinoid decarboxylase: GTP BVI01S_RS15110 dinucleotide D-arabino- 2-iminobutanoate with (L-alanyl-γ-D- strand (non- a mature a nascent met threonyl-[protein] met L-seryl-[protein] met a peptide formation of two trp RS20045 trp BVI01S_RS08690 2-reductase: carbamoyltransferase: BVI01S_RS05370 adenosylcobinamide phosphate D-erythrose for iron-sulfur 1-carboxylate adenosyltranferase]- panD GTP ppGpp heptulosonate aspartate-semialdehyde a [TusA sulfur- isobutanoyl-CoA glutamyl-meso-2,6- reducing terminus) peptidoglycan peptidoglycan D-glyceraldehyde DHAP D-glyceraldehyde DHAP intact strands [corrinoid BVI01S_RS07940 2,5-diamino-6-(5-phospho-D- argF L-ornithine kinase/ pyruvate 4-phosphate cob(II)inamide molybdopterin 7-phosphate dehydrogenase: asd (2S)-2- diaminopimeloyl-D- (meso-DAP 3-phosphate guanylyltransferase: cluster assembly: synthase: menH adenosyltranferase]- GTP carrier protein]-S- succinate adenosylcobinamide- with (L-alanyl- β ribosylamino)pyrimidin-4(3H)-one 3-dehydroquinate BVI01S_RS08695 BVI01S_RS20400 (R)-pantoate - cyclohydrolase molybdotransferase sulfanyl-L-cysteine methylbutanoyl-CoA ornithine--oxo-acid alanine) tetrapeptide γ-D-glutamyl- containing) with 2-succinyl-5- cob(II)inamide bifunctional nucleoside- synthase: carbamoyl phosphate adenosyl-cobinamide F0F1 ATP an S-sulfanyl-[cysteine I FolE: folE MoeA: L-aspartate 4-semialdehyde transaminase: meso-2,6- GlcNAc terminus H + H + enolpyruvyl- diaminohydroxyphosphoribosylaminopyrimidine GDP L-ornithine guanylyltransferase: synthase desulfurase]-[disordered- 7,8- BVI01S_RS17775 diphosphate BVI01S_RS08425 phosphate 2-oxobutanoate BVI01S_RS13965 diaminopimeloyl- phosphate 6-hydroxy-3- [corrinoid deaminase/5-amino-6-(5-phosphoribosylamino) pyrophosphokinase: bifunctional (p)ppGpp methylacrylyl-CoA BVI01S_RS08710 form scaffold pantoate--beta- dihydroneopterin superpathway of thiamine diphosphate biosynthesis II kinase: ndk D-alanine) cyclohexene- adenosyltranferase]- synthetase/guanosine- 3-dehydroquinate 4-hydroxy- a [TusD sulfur- carbamoyl L-glutamate-5- protein] complex [corrinoid alanine : 3'-triphosphate uracil reductase RibD: ribD MoO - BVI01S_RS19350 (E)-2- adenosyl- cob(I)inamide 2 tetrahydrodipicolinate enoyl-CoA phosphate synthase: tetrapeptide [cysteine desulfurase]-S- 1-carboxylic- adenosyltranferase]- molybdopterin 3',5'-bis(diphosphate) 3'- carrier protein]-S- methylcrotonoyl-CoA semialdehyde cobinamide H + RS09665 H + BVI01S_RS08305 5-amino-6-(5-phospho- a [ThiS sulfur- type II 3- synthase: dapA hydratase: BVI01S_RS12380 sulfanylcysteine:[acceptor acid synthase: cob(I)yrinic acid cob(I)inamide cys cofactor pyrophosphohydrolase: sulfanyl-L-cysteine enoyl-CoA phosphate a purine D-ribosylamino)uracil carrier protein] dehydroquinate (2S,4S)-4-hydroxy-2,3,4,5- BVI01S_RS20125 BVI01S_RS12385 L- degradation to protein]-cysteine menD a,c-diamide D-ribulose 5-phosphate BVI01S_RS19350 hydratase: propanoyl-CoA ribonucleoside cob(I)yrinic acid 7,8- bifunctional dehydratase: aroQ 2-amino-3-carboxymuconate sulfurtransferase: 2-succinyl-5- adenosyltransferase: (R)-pantothenate sulfur carrier cysteine tetrahydrodipicolinate enoyl-CoA - 5'-diphosphate a,c-diamide diaminohydroxyphosphoribosylaminopyrimidine GDP BVI01S_RS20125 semialdehyde ala ala BVI01S_RS15385 dihydroneopterin bifunctional protein ThiS desulfurase: hydratase: hydrolyzing (S)-1-pyrroline- RS22325 BVI01S_RS18280 enolpyruvoyl- adenosyltransferase: type III 3-dehydroshikimate dipicolinic acid a [TusE sulfur enoyl-CoA met met a [cysteine desulfurase]- 3'-phosphate 3,4-dihydroxy- deaminase/5-amino-6-(5-phosphoribosylamino) adenylyltransferase: BVI01S_RS13985 BVI01S_RS16190 5-carboxylate 6-hydroxy-3- cob(I)yrinic acid BVI01S_RS15385 chorismate synthetase: dpaA dpaB 34 carrier protein]-S carbamoyl- trp S-sulfanyl-[disordered- pantothenate 2-butanone- uracil reductase RibD: ribD BVI01S_RS03245 shikimate a uridine in tRNA hydratase: cyclohexene- a,c-diamide [+ 3 isozymes] -sulfanylcysteine (S)-3-hydroxy- phosphate propanoyl pyrroline-5- tryptophan 2,3- an N-formyl-L- sn-glycero-3- a mature hydrogen a [protein]- phosphoenol D-sedoheptulose an N-terminal- a [protein]-L- form scaffold cob(I)yrinic acid kinase: aminodeoxychorismate/ 5-amino-6-(5-phospho- a carboxy- an [L-cysteine dipicolinate BVI01S_RS16190 cob(II)inamide cob(II)alamin a reduced serotonin 1-carboxylate adenosyltransferase: 4-phosphate dehydrogenase: isobutanoyl-CoA synthase: carboxylate methionylaminoacyl- phospho-N- peptidoglycan 1-phosphate L-methionyl-L- met methionine BVI01S_RS13430 phosphate dioxygenase: ATP ATP (n) peroxide thioredoxin L-glutamine dGDP pyruvate protein] complex 2-succinyl-6- a,c-diamide anthranilate synthase/GTP D-ribitylamino)uracil adenylated-[ThiS desulfurase]-S- aroE (2S,3S)-3-hydroxy-2- valyl-[protein] peptide- met RS12680 met cysteine BVI01S_RS08690 D-erythro-7,8- Amine and Polyamine Biosynthesis tRNA 2- carB carA reductase: kynA tRNA (arachidonoyl) (meso-DAP n-acetylglutamate adenosyltransferase: (R)-4'- synthase: pabA pabB cyclohydrolase II: sulfur-carrier protein] sulfanyl-L-cysteine methylbutanoyl-CoA : N-Formyl-L- methionine hydroxy-2, 4- dihydroneopterin adenosylcobalamin thiouridine(34) proC ethanolamine containing) synthase: desulfurase: BVI01S_RS08690 phosphopantothenate BVI01S_RS15110 shikimate BVI01S_RS14050 transglutaminase fructose cyclohexadiene- adenosylcobinamide aminodeoxychorismate/ D-glyceraldehyde salvage from cobalamin synthase carbamate [+ 2 isozymes] peptide thioredoxin- type I methionyl BVI01S_RS05965 (S)-S-oxide BVI01S_RS13985 dihydroneopterin cysteine spermidine biosynthesis I Storage Compound cob(I)yrinic acid cob(I)yrinic acid domain-containing bisphosphate 1-carboxylate bifunctional anthranilate synthase 1-deoxy-L-glycero- 3-phosphate putrescine MnmA: mnmA (S)-3-hydroxy-isobutanoate : : deformylase: dependent aminopeptidase: reductase met RS05800 met [+ 3 isozymes] bifunctional adenosylcobinamide aldolase: folB gly desulfurase: : Biosynthesis a,c-diamide a,c-diamide glycerophosphodiester bifunctional lytic protein: pyruvate aldolase: bifunctional an S-sulfanyl-[cysteine synthase: menH phosphopantothenoylcysteine component II: tetrulose 4-phosphate ARP 1-deoxy-D-xylulose- cob(I)alamin biosynthesis I BVI01S_RS06505 pro kynB BVI01S_RS10785 thiol map MsrA: msrA (1R,6R)-6-hydroxy- adenosylcobinamide BVI01S_RS13985 BVI01S_RS06280 adenosyltransferase: adenosyltransferase: phosphodiesterase: transglycosylase/ BVI01S_RS05430 kinase: pyk BVI01S_RS13780 ornithine adenosylcobinamide decarboxylase/ BVI01S_RS20255 34 2-methylacetoacetyl-CoA desulfurase]-S- 2-succinylcyclohexa- 6-(hydroxymethyl) 5-phosphate SAM cyanophycin metabolism a 2-thiouridine propanoate BVI01S_RS08690 BVI01S_RS15385 peptide BVI01S_RS06480 C40 family peroxidase: type I methionyl acetyltransferase/ peptide- kinase/ : phosphopantothenate-- [+ 3 isozymes] sulfanyl-[disordered- -7,8-dihydropterin 4-amino-4- oxidase synthase: arg shikimate 3- in tRNA L-kynurenine bcp fructose- methionine 2,4-diene-1- adenosylcobinamide- 6,7-dimethyl-8- CO L-arginine cob(I)yrinic acid cob(I)yrinic acid deformylase: [+ 3 isozymes] peptidase: 6 aminopeptidase: N-acetylglutamate met RS06880 met BVI01S_RS08715 cysteine ligase CoaBC: coaBC phosphate 2 a [protein] N - bisphosphate form scaffold carboxylate (R)-1-amino- 2-amino-4-hydroxy-6- deoxychorismate ThiO: thiO BVI01S_RS06450 cob(II)alamin S-adenosylmethionine tRNA uridine-5- acetyl-CoA C- BVI01S_RS07685 BVI01S_RS12875 peroxiredoxin: map synthase: argJ (S)-S-oxide phosphate (R)-4'- ribityllumazine a thiocarboxylated- asp (S)-methylmalonate- degradation VI a,c-diamide a,c-diamide [(5-hydroxy-1H- pyruvate aldolase: protein] complex[cysteine desulfurase]-S- 2-propanol O hydroxymethyldihydropteridine 1-deoxy-D-xylulose decarboxylase proenzyme: 3-phosphoshikimate 1- carboxymethylaminomethyl(34) acyltransferase: ahpC dGTP N-acetyl-L- reductase o-succinylbenzoate guanylyltransferase: adenosylcobyrate phosphopantothenoyl- aminodeoxychorismate synthase: AIR 2-iminoacetate [ThiS sulfur- semialdehyde ( 2 pathway) adenosyltransferase: adenosyltransferase: [+ 3 isozymes] indol-3-yl)ethyl]- BVI01S_RS15835 -2-phosphate diphosphokinase: folK cob(I)yrinic acid BVI01S_RS16050 carboxyvinyltransferase: synthesis GTPase MnmE: mnmE BVI01S_RS09795 anandamide sn-glycerol methionine MsrA: msrA sulfanylcysteine:[acceptor synthase: menC BVI01S_RS08695 L-cysteine lyase: pabC BVI01S_RS15115 5-phosphate carrier protein] agmatine BVI01S_RS15385 BVI01S_RS08690 L-glutamine a protein-L- (7,8-dihydropterin- a,c-diamide aroA cyanophycin arg L- degradation I a L-methionylaminoacyl- 3-phosphate an N-terminal ala RS05450 ala protein]-cysteine phosphomethylpyrimidine adenosylmethionine tRNA uridine-5- formate a mature GlcNAc-1,6- an oxidized H O met methionine- bifunctional bifunctional 6-yl)methyl adenosyltransferase: 5-enolpyruvoyl- synthetase: 3-hydroxy- tRNA 2 L-valyl-[protein] sulfurtransferase: 2-succinylbenzoate 4-aminobenzoate synthase ThiC: thiC thiazole synthase: decarboxylase: speD agmatinase: carboxymethylaminomethyl(34) arginase: peptidoglycan anhMurNAc- thioredoxin D-erythrose (S)-S-oxide phosphopantothenoylcysteine 6,7-dimethyl-8-(1-D-ribityl)lumazine BVI01S_RS15385 shikimate 3- cphA acetyl-CoA propanoyl-CoA L-kynurenine adenosylcobinamide adenosylcobalamin (n) DHAP BVI01S_RS18280 adenosylcobinamide diphosphate BVI01S_RS03240 speB a [cysteine decarboxylase/ synthesis MnmG: mnmG rocF his triphosphate triphosphate (meso-DAP L-Ala-γ-D-Glu- o-succinylbenzoate- kinase/ adenosyl- HMP-P cob(I)yrinic acid putrescine dAdoMet phosphate arg cyanophycin (S)-3-amino-2- hydrogencarbonate desulfurase]-(S- phosphopantothenate-- dihydropteroate acyl carrier a 5-carboxymethylaminomethyl- L-ornithine : containing) DAP-D-Ala ala RS19510 ala -CoA ligase: adenosylcobinamide- cobinamide riboflavin 2-[(2R,5Z)-2-carboxy- a,c-diamide putrescine chorismate primer-L-aspartate methylpropanoate histidine sulfanyl) -[disordered- cysteine ligase CoaBC: coaBC synthase: folP protein activation synthase: ribE 2-thiouridine 34 in tRNA ammonia- kynU 2 BVI01S_RS14865 phosphate phosphate bifunctional 4-methylthiazol-5(2H)- synthase: adenosyltransferase: spermidine synthase: speE ornithine--oxo-acid form scaffold 4-(2'- guanylyltransferase: hydroxymethylpyrimidine ylidene]ethyl phosphate aroC cyanophycin lyase: hutH a peptidoglycan dimer an sn-glycero-3- a [bis(guanylyl bifunctional an apo acyl- BVI01S_RS08690 3-hydroxyanthranilate a nucleoside phosphoenol protein] complex 4'-phosphopantetheine 7,8- riboflavin L-serine transaminase: urocanate 34 H O an N-modified an L-asparaginyl- an L-cysteinyl- RNA a reduced carboxyphenyl)- BVI01S_RS08710 adenosylcobinamide kinase/ synthetase: a 5,10-gly a uridine with pentapeptide diphosphate 2 phospho-N-(acyl) molybdopterin) cys RNA carrier protein cob(II)alamin- aminoacyl-[tRNA] triphosphate dADP pyruvate [tRNA Asn ] [tRNA Cys ] ATP roseoflavin dihydropteroate phosphomethylpyrimidine chorismate cphA degradation BVI01S_RS13965 methylenetetrahydrofolate in tRNA ethanolamine H O c-type 4-oxobutyryl-CoA kinase/ pantetheine- holo-ACP synthase: bifunctional [corrinoid spermidine a 5-aminomethyl-2- urocanate stems (meso- cofactor 5'-phosphate 2 adenosyl-cobinamide kinase: thiD L- degradation I L-glutamate-5- cytochrome 1,4- adenosylcobinamide- phosphate bifunctional BVI01S_RS17200 / 2-(2-carboxy-4- adenosyltranferase] thiouridine 34 in tRNA hydratase: diaminopimelate chaperone]- RS07275 an oxidized phosphate ser semialdehyde ribonuclease a [cysteine desulfurase]- dihydroxy-2- phosphate adenylyltransferase: folylpolyglutamate a holo acyl- FAD synthetase: ribF methylthiazol-5- asp hutU 2-amino-3- tRNA uridine-5- containing) manganese- glycerophosphodiester L-cysteine peptidyl-tRNA DNA-directed peptidyl-tRNA peptidyl-tRNA O c-type HMP-PP cyanophycin 2 bifunctional synthase/ carrier protein L-serine dependent inorganic RNA PH: rph bifunctional a reduced [scaffold protein- (2E,6E)-farnesyl naphthoyl- guanylyltransferase: coaD yl)ethyl phosphate pro 4-imidazolone- carboxymuconate- carboxymethylaminomethyl(34) phosphodiesterase: : pyruvate hydrolase: hydrolase: cytochrome IPP adenosylcobinamide dihydrofolate FMN ammonia- pyrophosphatase: riboflavin H O c-type CoA BVI01S_RS08695 BVI01S_RS06080 BVI01S_RS09005 subunit beta: 2 (2Fe-2S)] complex diphosphate 3'-dephospho- cob(I)alamin- proline 5-propanoate 6-semialdehyde synthesis GTPase MnmE: mnmE N-acetylmuramoyl- cysteine kinase: pyk BVI01S_RS09005 BVI01S_RS09005 cytochrome synthase: kinase/ synthase: thiamine phosphate cyanophycin a 5-methylaminomethyl- lyase, BVI01S_RS12750 BVI01S_RS01360 kinase/FAD cytochrome bifunctional CoA bifunctional [corrinoid dehydrogenase: tRNA uridine-5- L-alanine [+ 3 isozymes] desulfurase: aminoacyl-tRNA aminoacyl-tRNA aminoacyl-tRNA c oxidase an oxidized menB adenosylcobinamide- BVI01S_RS11370 synthetase: 2-thiouridine 34 in tRNA iron-sulfur- (S)-1-pyrroline- : pyrophosphatase [+ 4 isozymes] a nucleoside RNA synthetase: heptaprenyl adenosylcobinamide dephospho- riboflavin kinase/ synthase: adenosyltranferase] BVI01S_RS06955 carboxymethylaminomethyl(34) BVI01S_RS18280 hydrolase: hydrolase: hydrolase: O c-type phosphate cphA (S)-1-pyrroline- dependent: 5-carboxylate BVI01S_RS01475 diphosphate ribF 2 diphosphate 1,4-dihydroxy-2- 7,8-dihydrofolate BVI01S_RS03225 cob(I)yrinic acid Tetrapyrrole Biosynthesis tRNA 2- synthesis enzyme MnmG: mnmG CwlD: cwlD PpaX: ppaX BVI01S_RS13530 BVI01S_RS13530 BVI01S_RS13530 cytochromea reduced a [co-chaperone]- kinase/ CoA kinase: FAD synthetase: ribF 5-carboxylate sdaAA sdaAB sn-glycerol an N- [+ 3 isozymes] pyruvate naphthoyl-CoA guanylyltransferase: monoglutamate thiamine phosphate selenouridine(34) 2-aminoprop- pyrroline-5- L-tryptophan dATP H O b(o/a)3-type c-type [scaffold protein- synthase: hepT adenosylcobinamide- BVI01S_RS21125 a,c-diamide N-formimino- acylethanolamine 2 BVI01S_RS08695 FAD arg [cyanophycin]- synthase carboxylate degradation I γ 3-phosphate RNA roseoflavin cytochrome BVI01S_RS08455 phosphate synthase: adenosyltransferase: tetrapyrrole biosynthesis 2-enoate L-glutamate 34 a peptidoglycan dimer L-alanyl- -D- cytochrome- an oxidized (2Fe-2S)] complex a 5-carboxymethylaminomethyluridine + a [bis(guanylyl coenzyme A siroheme biosynthesis L-aspartate MnmH: mnmH reductase: (via anthranilate) phosphate H an N-modified an uncharged adenine bifunctional guanylyltransferase: BVI01S_RS03255 BVI01S_RS15385 I (from glutamate) a 7,8-dihydrofolate with pentapeptide stem glutamyl-meso-2,6- ala molybdopterin) asn tRNA Asn cys a tRNA Cys O c oxidase c-type a 5-methylaminomethyl- proC : in tRNA tRNA dinucleotide 2 all-trans- adenosylcobinamide BVI01S_RS08710 (meso-diaminopimelate diaminopimeloyl- cofactor amino acid acytochrome reduced cob(I)yrinic acid cyanophycin L-glutamate-5- hutG trp heptaprenyl 1,4-dihydroxy- kinase/ a 7,8-dihydrofolate uroporphyrinogen-III 2-(S-geranyl) [+ 2 isozymes] containing) D-alanyl-D-alanine H O c-type a,c-diamide glu semialdehyde chaperone]-S- 2 a [chaperone-ATP]- diphosphate 2-naphthoate adenosylcobinamide- thiamine phosphate uroporphyrinogen-III synthetase: thiouridine 34 in tRNA tryptophan 2,3- cytochrome adenosylcobinamide- adenosyltransferase: glutamate-- 2-iminopropanoate sulfanyl-L-cysteine ancytochrome oxidized [co-chaperone]- GDP dihydrofolate superpathway of pyridoxal 5'-phosphate biosynthesis and salvage C-methyltransferase: cphA tRNA 2- L-glutamate pro glu dioxygenase: c oxidase phosphate BVI01S_RS08690 tRNA ligase: O c-type [scaffold protein- 1,4-dihydroxy- reductase: thiamine diphosphate salvage IV (yeast) cobA selenouridine(34) gamma- kynA 2 guanylyltransferase: folate transformations III (E. coli) D-erythrose adenosylcob(III) BVI01S_RS17355 N-Formyl-L- L-threonine biotin RS18300 cytochromebiotin (2Fe-2S)] complex 2-naphthoate BVI01S_RS21070 an L-glutamyl- precorrin-1 synthase semialdehyde a 5,10- a 2-thiouridine 34 a [DNA]-3'- a 5'-phospho- a 2,3,4-saturated a 2'- an N-terminal- an N-terminal- an N-terminal- a [peptide] BVI01S_RS08710 alamin-[corrinoid cyanophycin glycine cleavage kynurenine degradation III (to + 37 + 4-phosphate Glu NAD an adenosine NADP FMNH MoO - N-ethylglycine polyprenyltransferase: [tRNA ] MnmH: mnmH dehydrogenase: methylenetetrahydrofolate in tRNA hydroxyl [DNA] 1,2-diacyl-sn- DMAPP deoxyribonucleoside [DNA] L-methionyl-L- 2 2 L-methionyl-L- L-methionyl- with N-terminal adenosylcobinamide- a tetrahydrofolate thiamine adenosyltranferase] arylformamidase: methylglyoxal) CTP in tRNA ATP molybdopterin BVI01S_RS14890 a tetrahydrofolate thiamine diphosphate uroporphyrinogen-III cyanophycinase: a 5-methylaminomethyl- pruA pyruvate a [glycine- glycerol 3-phosphate 5'-triphosphate cysteinyl-[protein] alanyl-[protein] glycyl-[protein] β aspartate GDP cob(I)yrinic acid glutamyl-tRNA kynB cofactor C-methyltransferase: BVI01S_RS15215 2-(Se-phospho) cleavage complex L-methionine thr a,c-diamide reductase: 34 tRNA uridine-5- DNA ligase D: oxygen- glycine biotin RS14770 biotin a [chaperone- cobA selenouridine in tRNA glu H protein] N 6 -[(R tRNA (adenosine(37)-N6) group II beta- an [2Fe-2S] 4-phospho- BVI01S_RS11420 cyanophycinase: degradation II L-threonine 3- carboxymethylaminomethyl(34) BVI01S_RS15140 phosphatidate type I methionyl insensitive type I methionyl type I methionyl oxidase ADP]-[disordered- demethylmenaquinol-7 dihydrofolate methionine bifunctional II: tenA adenosyltransferase: tRNA 2- )-lipoyl]-L- aminomethyltransferase L-kynurenine -dimethylallyltransferase molybdenum cofactor cluster protein D-erythronate precorrin-2 BVI01S_RS03185 dehydrogenase: cytidylyltransferase: intron reverse aminopeptidase: aminopeptidase: aminopeptidase: ThiO: thiO aspartyl- form scaffold reductase: synthase: 5,10-methylene- BVI01S_RS15385 (S)-4-amino-5- selenouridine(34) GcvT: gcvT synthesis GTPase MnmE: mnmE NAD- MiaA: miaA NADPH guanylyltransferase: demethylmenaquinone erythronate- N-β-aspartyl- glycine cleavage system met BVI01S_RS16930 BVI01S_RS09300 transcriptase/ map map map peptidase: protein] complex bacillithiol biosynthesis BVI01S_RS21070 metH tetrahydrofolate 4-amino-2-methyl-5- 5-(2-hydroxyethyl) cob(I)yrinic acid oxopentanoate synthase L-2-amino-3- tRNA uridine-5- dependent nitroreductase: Zn 2+ RS17670 Zn 2+ methyltransferase: precorrin-2 L-arginine aminomethyltransferase [+ 2 isozymes] kynureninase: phosphatidate maturase: ltrA BVI01S_RS17735 iadA dehydrogenase/ 4-phosphate pyrimidinemethanol -4-methylthiazole MnmH: mnmH methionine oxobutanoate carboxymethylaminomethyl(34) DNA ligase type I methionyl nfsA type I methionyl type I methionyl a,c-diamide glutamate-1- dehydrogenase: GcvT: gcvT kynU N 6 -(3-methylbut- BVI01S_RS08450 5,10-methylene- dehydrogenase: a 5-methylaminomethyl- gamma- cytidylyltransferase: group II aminopeptidase: aminopeptidase: aminopeptidase: ethylamine glyoxylate UDP-N-acetyl- serine a (6S)-5- bifunctional adenosyltransferase: semialdehyde BVI01S_RS03370 D-serine degradation synthesis enzyme MnmG: mnmG LigA: ligA 2-en-1-yl)- adenylyl (S)-malate tetrahydrofolate BVI01S_RS10990 beta- 2-selenouridine 34 [+ 3 isozymes] lyase: megL BVI01S_RS03170 intron reverse map map map α formyltetrahydrofolate a [glycine- (2Z)-2-aminobut- 37 menaquinol-7 -D-glucosamine a 7,8-dihydrofolatehydroxymethyltransferase:a 5-methyltetrahydrofolate hydroxymethylpyrimidine BVI01S_RS08690 2,1-aminomutase: anthranilate molybdenum 2+ 2+ an [Fe-S cluster aspartyl- a [glycine-cleavage adenosine + Zn RS14840 Zn glycine cleavage systemcyclohydrolase: (3R)-3-hydroxy-2-oxo- sirohydrochlorin in tRNA cleavage complex 2-enoate transcriptase/ FMN NADPH H asp a peptide biosynthesis BVI01S_RS01195 5-formyltetrahydrofolate kinase/ 4-methyl-5-(2- BVI01S_RS15350 complex H protein] N 6 - a 5-aminomethyl-2- in tRNA cofactor aminomethyltransferaseBVI01S_RS16890 adenosylcobalamin peptidase: tRNA processing D-serine 6 maturase: ltrA N-acetyl- cyclo-ligase: 4 phosphooxybutanoate phosphomethylpyrimidine H protein] N - a 7,8-dihydrofolate 34 [DNA] NMN a CDP-2,3,4-saturated- an N-terminal L- an N-terminal L- an N-terminal chaperone]-ATP phosphooxyethyl) glutamate-1- sirohydrochlorin iadA D-serine aminomethyldihydrolipoyl- aminoacetone thiouridine in tRNA AMP alpha-D- GcvT: gcvT bifunctional BVI01S_RS12180 D-glyceraldehyde 3-phosphoserine/ kinase: thiD dihydrolipoyl- diacylglycerol met cysteinyl-[protein] met alanyl-[protein] met glycyl-[protein] pyruvate thiazole semialdehyde chelatase: L-threonine L-lysine glucosaminyl bifunctional homocysteine 3-phosphate phosphohydroxythreonine a polycistronic ammonia-lyase: L-lysine a metal a metal methylenetetrahydrofolate5-formyltetrahydrofolate thiamine phosphate 2,1- degradation II [DNA] bis(guanylyl molybdopterin) thymidylate HMP-P BVI01S_RS03365 tRNA precursor BVI01S_RS20660 L-glutamate cation cation L-malate S-methyltransferase/ dehydrogenase/ cyclo-ligase: transaminase: serC synthase: aminomutase: arg asp 2-aminoprop- 2-iminobutanoate RS21150 cofactor sulfurylation synthase: 1-deoxy-D-xylulose- degradation II synthase methylenetetrahydrofolate methenyltetrahydrofolateBVI01S_RS18690 4-phosphooxy- BVI01S_RS03225 S-adenosyl-L-methionine salvage I hemL siroheme 2-enoate NAD de novo biosynthesis BVI01S_RS21075 bifunctional 2-methyladeninyl thr ala ala BshA: bshA reductase: BVI01S_RS11590 cyclohydrolase FolD: folD 5-phosphate L-threonine glycine cleavage system methylglyoxal I (from aspartate) a 5,10- a 5,10- hydroxymethylpyrimidine thiamine phosphate adenosylcobamide biosynthesis L-threonine 3- UDP-N-acetyl-α-D-muramoyl- (2-hydroxyphenyl) a 1-acyl-2- a [protein]-L- cys synthase: 5-aminolevulinate aminomethyltransferase glu di-trans,octa-cis- a carboxy- a lipid II a D-aspartyl- D-ribose 5- a metal a metal methylenetetrahydrofolate methenyltetrahydrofolate kinase/ synthase: from adenosylcobinamide-GDP γ glu a (6S)-5- NaMN glutamate-O 5 fosfomycin bacillithiol RS08870 dehydrogenase: L-alanyl- -D-glutamyl-L- adenylated- cys methyl 1-hydroxy- arachidonoyl- asp phosphate cation cation (S)-malyl N- BVI01S_RS06450 SAH a tRNA precursor a tRNA precursor GcvT: gcvT undecaprenyl phosphate [tRNA ] IMP asp α pyridoxine phosphomethylpyrimidine BVI01S_RS03255 BVI01S_RS16930 lysyl-D-alanyl-D-alanine [ThiS sulfur- formyltetrahydrofolate 6-oxocyclohex-2- sn-glycerol bifunctional -methyl-ester ribose-5- cysteine acetyl- -D- bifunctional 2-methyladenine porphobilinogen 2-iminopropanoate L-2-amino-3- L-glutamine 2-oxobutanoate 1-deoxy-D- 3-amino-1- kinase: thiD with a 5' with a 5' carrier protein] ene-1-carboxylate 3-phosphate CTP metallophosphatase/ bifunctional phosphate L-aspartate desulfurase: glucosaminide 5,10-methylene- thiamine 5'-methylthioadenosine/ synthase: hemB oxobutanoate degradation I D-Ala-D-Ala metallothiol pyridoxamine extension and extension and a asp phospho-N- 5'-nucleotidase: metallophosphatase/ oxidase: nadB BVI01S_RS13985 bacillithiol tetrahydrofolate xylulose 5- hydroxyacetone phosphate S-adenosylhomocysteine L- bifunctional carboxypeptidase D-tyrosyl-tRNA(Tyr) chemotaxis a metal a metal NAD salvage pathway I (PNC VI cycle) pyridoxine/ HMP-PP a long 3' trailer short 3' extension glycine C- BVI01S_RS05000 5'-nucleotidase: RpiA: rpiA RS12490 2-iminosuccinate biosynthesis dehydrogenase/ phosphate 1-phosphate nucleosidase: porphobilinogen L-glutamine degradation I acetylmuramoyl- cysteine folylpolyglutamate phosphatidate VanY: deacylase: response regulator cation cation [+ 3 isozymes] pyridoxal/ pyridoxine/ ribonuclease gln aspartate carboxylesterase: BVI01S_RS20420 FosB: fosB an [L-cysteine 5,10-methylene- acetyltransferase: pentapeptide- synthase/ BVI01S_RS14925 bifunctional BVI01S_RS19355 protein-glutamate ribose 5- deacetylase pyridoxamine pyridoxal/ thiamine diphosphate BVI01S_RS10355 P protein degradation II Asp-tRNA(Asn) desulfurase: BVI01S_RS07415 cytidylyltransferase: + BVI01S_RS16925 ammonia- transferase: bifunctional quinolinate desulfurase]-S- BshB2: bshB2 NAD tetrahydrofolate pyridoxamine hydroxymethylbilane pyruvate BVI01S_RS18280 dihydrofolate BVI01S_RS09300 metallophosphatase/ methylesterase: phosphate : pdxK biosynthesis III 5'-methylthioadenosine/ 2-methyladenine component: /Glu-tRNA(Gln) lyase: aspA asn bacillithiol- synthase sulfanyl-L-cysteine cyclohydrolase: synthase: hemC BVI01S_RS07890 [+ 3 isozymes] synthase: 5'-nucleotidase: BVI01S_RS09240 metallophosphatase/ isomerase a metal a metal bacillithiol kinase: pdxK (Staphylococcus) thiamine S-adenosylhomocysteine adenosylcobinamide- ribotide phosphate ribonuclease rnpA gly gln amidotransferase: : phosphatidate a N- NadA: nadA cysteine 1-hydroxy-6- asp 5'-nucleotidase: fosfomycin cation cation BVI01S_RS16890 2-(2-carboxy-4- nucleosidase: mtnN GDP PH: rph a tRNA precursor glutamate fumarate BVI01S_RS11370 cytidylyltransferase: D-ala acetylglucosamine- BVI01S_RS20420 tRNA D-aspartate B: rpiB bis(guanylyl biosynthesis ammonia- pyridoxine pyridoxamine preuroporphyrinogen BVI01S_RS12380 BVI01S_RS08560 salicyl β-D- BVI01S_RS05000 D-ribulose RS03410 desulfurase: pyridoxine/ methylthiazol-5- thiamine with a short synthase large undecaprenyl-diphospho-N- oxocyclohex-2- quinolinate molybdopterin) deacetylase dependent bifunctional 5'-phosphate 5'-phosphate HMP-PP polyribonucleotide BVI01S_RS12385 UMP a thiocarboxylated- BVI01S_RS03170 -N-acetylmuramyl- ribosylnicotinate a [protein]-α- 5-phosphate BVI01S_RS13985 ammonia- pyridoxal/ yl)ethyl phosphate diphosphokinase: S-ribosyl-L- asp L-alanine acetylmuramoyl-L-alanyl-γ-D- ene-1-carboxylate MeOH inosine ala ala cofactor BshB1: bshB1 NAD(+) methylenetetrahydrofolate adenosylcobinamide- uroporphyrinogen- : pnp3' extension subunit: gltB gatC gatA gatB ala [ThiS sulfur- a (6S)-5- (tetrapeptide) L-glutamate [+ 3 isozymes] dependent pyridoxamine BVI01S_RS07650 homocysteine glu degradation IV glutamyl-L-lysyl- D-alanyl-D-alanine AMP a metal a metal carboxylating (S)-malyl α-D- synthetase: dehydrogenase/ GDP III synthase: a tRNA [+ 11 isozymes] carrier protein] formyltetrahydrofolate a CDP-1-acyl- pyrophosphoryl- RS16380 a [bis(guanylyl NAD(+) kinase: pdxK thiamine phosphate cation cation nicotinate- glucosaminide nadE methenyltetrahydrofolate thiamine ribazoletransferase: BVI01S_RS11405 precursor with glu 2-arachidonoyl- undecaprenol molybdopterin) synthetase: synthase: S-ribosylhomocysteine ala nucleotide cyclohydrolase FolD: folD diphosphate cobS a 5' extension ribonuclease glycerol cofactor [bis-MGD cofactor bacillithiol nadE BVI01S_RS03225 lyase: uroporphyrinogen-III diphosphorylase: 10 adeninyl adenosylcobamide PH: rph alanine chaperone]-S- chaperone]- biosynthesis an N - PLP nadC nicotinate adenine biosynthesis from thiamine phosphate BVI01S_RS14830 Coα-[α-(2- ribonuclease dehydrogenase: ald a metal a metal bis-MGD NMN formyltetrahydrofolate UDP-N-acetyl-α-D- ditrans,octacis- a [protein] N- N-acetyl-α- RS03755 sulfanyl-L-cysteine cysteine- dinucleotide cytochrome c biogenesis synthase: methyladenin-9-yl)]-Co pyruvate cation cation adenosylcobinamide-GDP P protein di-trans,octa-cis- γ S-methyl-L- glycerophosphoserine methyl red H O Se-methyl-L- β-aspartyl dipeptide L-canavanine NaMN adding muramoyl-L-alanyl- -D- undecaprenyldiphospho- L-homocysteine terminal-formyl- 2 D-muramoyl- a protein (system II type) BVI01S_RS03255 β-adenosylcobamide component: Fatty Acid and Lipid Degradation undecaprenyl phosphate methionine GTP selenocysteine enzyme benzimidazolyl AI-2 L-homocysteine glutamyl-L-lysyl-D-alanine N-acetyl-(N- L-methionine L-alanine(1-) ATP-dependent nicotinate-nucleotide adenine 5'-phosphate rnpA BshC: bshC a reduced adenosylcobamide biosynthesis acetylglucosaminyl)muramate Clp protease a metal a metal nicotinate-nucleotide thiamine β glycerophosphodiester FMN-dependent beta-aspartyl- RS12055 adenylyltransferase: sulfo-bis(guanylyl 5-methylbenzimidazolyl thioredoxin from adenosylcobinamide-GDP methionine oleate -oxidation arginase: lipoate salvage II fatty acid β-oxidation I (generic) phospho-N- bifunctional homocysteine peptide GTPase methionine N-acetylmuramoyl- proteolytic subunit: cation cation BVI01S_RS17895 molybdopterin) bacillithiol adenylyltransferase: phosphate synthase: phosphodiesterase: NADH- peptidase: rocF adenosylcobamide biosynthesis benzimidazole acetylmuramoyl- delta-lactam- S-methyltransferase/ deformylase: gamma- L-alanine BVI01S_RS09425 cofactor BVI01S_RS17895 a [lipoyl-carrier Coα-[α-(2- BVI01S_RS06080 azoreductase: HflX: hflX iadA nicotinate adenine from adenosylcobinamide-GDP heme b biosynthesis II metH oleate a (3Z)-alk-3- pentapeptide- biosynthetic de-N- methylenetetrahydrofolate BVI01S_RS10785 lyase: megL amidase [+ 2 isozymes] protein]-N 6 -[(R methyladenin-7-yl)]-Co an uncharged [+ 3 isozymes] BVI01S_RS15155 [+ 8 isozymes] dinucleotide (oxygen-independent) enoyl-CoA transferase: acetylase: pdaA reductase: BVI01S_RS11590 CwlD: cwlD a metal a metal 5-methylbenzimidazole an apo-[c-type a ResA protein )-lipoyl]-L-lysine met β-adenosylcobamide tRNA long-chain-fatty- peptide a peptide ammonia- ammonia- BVI01S_RS07890 FMN-dependent a proteinogenic cation cation adenine ribotide ∆ 3 2 deformylase: + L-canaline cytochrome] with with reduced thiamine acid--CoA ligase: -cis-∆ -trans- NADH- H methaneselenol pyruvate asp RS09635 dependent dependent thiamine diphosphate NaMN nicotinamide adenosylcobinamide- phosphate benzimidazole uroporphyrinogen-III ditrans,octacis- sn-glycerol BVI01S_RS07685 phosphate amino acid N-acetyl-D- a dislufide bridge cysteine residues methionine BVI01S_RS07045 enoyl-CoA ser azoreductase: GDP ala ala NAD(+) NAD(+) biosynthesis I (E. coli) (R)-lipoate GDP adenosylcobinamide- ribotide uroporphyrinogen undecaprenyl-diphospho-N acetate undecaprenyldiphospho- met 3-phosphate ala muramate nicotinate thiamine adenosyltransferase: [+ 5 isozymes] isomerase: UMP BVI01S_RS03725 synthetase: synthetase: GDP phosphate decarboxylase: hemE -acetylmuramoyl-L-alanyl-γ- (N-acetylglucosaminyl) a metal a metal 2-[(2R,5Z)- phosphoribosyltransferase: thiol-disulfide lipoate-- diphosphokinase: BVI01S_RS14755 BVI01S_RS20125 RS19870 nadE nadE adenosylcobinamide- 5-methylbenzimidazole lipoprotein posttranslational D-glutamyl-L-lysyl- D-alanine muramic δ-lactam an N-terminal L- cation cation 2-carboxy-4- BVI01S_RS20970 protein ligase: adenosylcobinamide- BVI01S_RS07650 coproporphyrinogen III oleoyl-CoA formate GDP ribotide phosphate modification methionyl-[protein] + GDP adenosylcobinamide- N,N-dimethyl-1,4- NAD methylthiazol-5(2H nicotinate ResA: resA BVI01S_RS18575 thiamine SAM a (2E)-2- anthranilate ribazoletransferase: GDP oxygen-independent a [prolipoprotein]- acyl-CoA enoyl-CoA phenylenediamine )-ylidene]ethyl phosphoribosyltransferase: [(R)- diphosphate enoyl-CoA HMP-PP adenosylcobinamide- an apo-[c-type ribazoletransferase: coproporphyrinogen L-cysteine dehydrogenase: hydratase: a metal a metal phosphate BVI01S_RS16005 cobS molybdopterin biosynthesis RS15545 GDP lipoyl]adenylate cobS III oxidase: BVI01S_RS15780 BVI01S_RS20125 cation cation heme a biosynthesis cytochrome] prolipoprotein RNase III mRNA a DNA containing DNA with adenine:7,8- a protein-L- ribazoletransferase: lipoate-- Coα-[α-(adenin-9-yl)]- a [ThiI sulfur- a peptidoglycan a 2'- (S)-1-pyrroline- thiamine phosphate with reduced L- BVI01S_RS17825 diacylglyceryl [+ 2 isozymes] enoyl-CoA hydrogen selenide a uracil in tRNA a RNA-DNA hybrid protoheme β α α O-acetyl-L-serine carrier protein]- processing an apurinic/ dimer (generic) dihydro-8- deoxyribonucleoside L-homocysteine IPP GGPP 5-carboxylate methionine- di-trans,poly-cis cobS cysteine residues protein ligase:Co -adenosylcobamide Co -[ - transferase: (2E,9Z)- a 2,3,4-saturated acyl-CoA/acyl-ACP hydratase: a 2,3,4- protoheme synthase: nicotinate protoporphyrinogen IX acyl--CoA ligase: apyrimidinic site oxoguanine mismatch deoxynucleoside L-glutamate (R)-S-oxide -undecaprenyl BVI01S_RS18575 5'-phosphate dipyrromethane (benzimidazolyl)]-Co cys GTP fatty acid dehydrogenase: S-sulfanyl- bifunctional peptide- a metal a metal protoheme IX BVI01S_RS03225 tetrahydrofolate salvage from α α BVI01S_RS11050 octadecenoyl-CoA BVI01S_RS16190 saturated (3R)-3- kinase: gamma- RS19330 Co -[ -(5- holocytochrome- a [glycine- β-adenosylcobamide ATP BVI01S_RS14000 L-cysteine bifunctional lytic methionine cation cation phosphate biosynthesis cofactor biosynthesis enoyl-CoA BVI01S_RS09645 a 2,3,4- hydroxyacyl-CoA ribonuclease HIII: BVI01S_RS21505 cystathionine semialdehyde farnesyltransferase: thiamine phosphate 5,10-methenyltetrahydrofolate methylbenzimidazolyl)]- cleavage complex 5'-phosphate cysteine prolipoprotein [+ 5 isozymes] O-acetylhomoserine Mini-ribonuclease 3: endonuclease A/G-specific heptaprenyl (2E,6E)-farnesyl c synthase: ccsB GTP 3',8- a 2,3,4-saturated[+ 2 isozymes] saturated (3S)-3- tRNA 4- transglycosylase/ BVI01S_RS16150 gamma-lyase/ (R)-S-oxide BVI01S_RS18035 synthase: IPP Coβ-adenosylcobamide H protein] N 6 -[(R an apo-[hydroxymethylbilane desulfurase: diacylglyceryl hydratase: aminocarboxypropyltransferase/ deoxynucleoside diphosphate dehydrogenase: diphosphate cyclase fatty acyl CoA BVI01S_RS17370 III: nth C40 family adenine homocysteine reductase ferroheme o BVI01S_RS03255 a 5,10-methenyltetrahydrofolate 5'-phosphate )-lipoyl]-L-lysine Coα-[α-(adenin-7-yl)]- synthase]-L-cysteine BVI01S_RS13985 transferase: BVI01S_RS16190 hydroxyacyl-CoA Detoxification cysteine synthase: thiouridine(8) ribonuclease HII: kinase: synthase: hepT pruA a c-type MoaA: moaA ribonuclease III: endonuclease peptidase: glycosylase: desulfhydrase: MsrB: msrB fluoride CrcB fluoride bifunctional 5,10- Coβ-adenosylcobamide protoporphyrin IX BVI01S_RS07375 enoyl-CoA BVI01S_RS10885 synthase BVI01S_RS07520 BVI01S_RS21510 BVI01S_RS08455 α α [+ 3 isozymes] (8S)-3',8-cyclo-7,8- BVI01S_RS07585 VIII: nei BVI01S_RS12875 mutY a 2'- BVI01S_RS18400 glu heme A synthase: methylene-tetrahydrofolate isoprenyl cytochrome Co -[ - an [L-cysteine a carboxy-adenylated a [prolipoprotein]- ThiI: thiI [+ 2 isozymes] thiamine a [hydroxymethylbilane dihydroguanosine hydratase: reactive oxygen degradation [+ 2 isozymes] deoxyribonucleoside a [protein]-L- BVI01S_RS18040 transferase: (benzimidazolyl)]-Co ferrochelatase: S-1,2-diacyl-sn- arsenate 8-oxo-(d)GTP detoxification I [+ 3 isozymes] 2-oxobutanoate phosphate dehydrogenase/5,10- synthase] ES intermediate desulfurase]-S- [small subunit of 5'-triphosphate BVI01S_RS20125 coenzyme A all-trans- methionine Coα-[α-(5- adenosylcobalamin biosynthesis a [lipoyl-carrier 2 β a [ThiI sulfur- RNase III a nucleoside 5'- 5'-monophosphate methylene-tetrahydrofolate BVI01S_RS09295 -adenosylcobamide hemH sulfanyl-L-cysteine molybdopterin synthase] glyceryl-L-cysteine detoxification a 4-thiouracil a 3'-terminal a 5'-phospho- an apurinic site DNA 6 an mRNA fragment fluoride CrcB fluoride ferroheme i methylbenzimidazolyl)]- from adenosylcobinamide-GDP I protein]-N -[(R hydroxymethylbilane cyclic pyranopterin (S)-3-hydroxy-(9Z) superoxide carrier protein]- processing within DNA monophosphate heptaprenyl cyclohydrolase: III (thioredoxin) acetate L-selenocysteine in tRNA unsaturated sugar [DNA] GlcNAc-1,6- adenine di-trans,octa-cis Coβ-adenosylcobamide )-lipoyl]-L-lysine monophosphate -octadecenoyl-CoA L-cysteine mRNA a lipid II diphosphate BVI01S_RS16890 synthase: hemC protoheme signal a 2,3,4-saturated a 2,3,4-saturated dGTP GTP anhydro-MurNAc- heme A synthase: -undecaprenyl 5,6-dimethylbenzimidazole synthase superoxide dismutase: arsenate a [hydroxymethylbilane peptidase fatty acyl CoA acetyl-CoA C- 3-oxoacyl-CoA pentapeptide BVI01S_RS18040 thiamine bifunctional diphosphate MoaC: moaC BVI01S_RS19065 arsenate L-cystine RS03260 L-cystine bis(guanylyl molybdenum synthase] ES intermediate a thiocarboxylated II: lspA acyltransferase: diphosphate methylenetetrahydrofolate undecaprenyl- 3 reductase cyclic pyranopterin 6 cofactor) biosynthesis [small subunit of 3-oxo-(9Z)- BVI01S_RS09795 (thioredoxin) 8-oxo-dGTP 8-oxo-GTP an N -L- an all-trans- 3-benzyl-3,6 - 1402 a diphthine- an oxidized hydroxyferroheme i dehydrogenase/ diphosphate hydroxymethylbilane phosphate an (S-diacyl- hydrogen peroxide a cytidine a D-tyrosyl- (indol-3-yl) cytidylyl molybdenum folate polyglutamylation molybdopterin synthase] a lipoprotein a sulfurated 37 MoO - 1,4-dihydroxy- an arylamine nitroaromatic methenyltetrahydrofolate MoO - octadecenoyl-CoA : arsC threonylcarbamoyladenine 2 polyisoprenyl bis(cysteinylglycine) in 16S rRNA Tyr acetamide [translation phosphatase: 2 synthase: hemC sn-glyceryl) GTP ATP [tRNA ] dGDP cofactor sulfurylation signal peptide 8-oxo-dGTP [sulfur carrier] molybdopterin a tRNA precursor 2-naphthoate 16S rRNA arylamine N- compound 2+ 2+ cyclohydrolase FolD: folD α-ribazole 5'-phosphate molybdopterin acetyl-CoA C- arsenite in tRNA molybdopterin diphosphate - 6-(hydroxymethyl) amidase domain- elongation oxygen- Ca Cax Ca BVI01S_RS15050 adenosylcobinamide-GDP molybdopterin a [hydroxymethylbilane -L-cysteinyl- catalase: diphosphatase: cofactor CTP diphthine-- ribonucleotide- an N 10 -formyltetrahydrofolate cofactor cytidylyl molybdenum a tetrahydrofolate signal acyltransferase: -diketopiperazine (cytosine(1402)-N(4) containing protein: acetyltransferase: factor 2] insensitive hydroxymethylpyrimidine thioredoxin [+ 2 isozymes] synthase] ES intermediate [apolipoprotein] BVI01S_RS15180 BVI01S_RS11130 ammonia ligase: diphosphate cofactor (trioxo) 4 peptide BVI01S_RS09795 )-methyltransferase D-tyrosyl-tRNA(Tyr) BVI01S_RS22415 BVI01S_RS05110 NADPH di-trans,octa-cis acetyl-CoA 8-oxo-GMP tRNA (N(6)-L- 1,4-dihydroxy- reductase: ferroheme a salvage pathway adenosylcobinamide-GDP molybdenum cofactor hydroxymethylbilane peptidase catalase/peroxidase molybdenum cofactor CCA tRNA RsmH: rsmH amidase domain- arylamine N- BVI01S_RS11460 phosphoribosylglycinamide -undecaprenyl serine molybdopterin guanylyl molybdenum H O hydroxyl radical 8-oxo-dGMP threonylcarbamoyladenosine(37) 2-naphthoate membrane deacylase: nitroreductase: formate-- bifunctional (7Z)-hexadecenoyl-CoA 2 BVI01S_RS17115an anion RS05035 an anion formyltransferase: purN ribazoletransferase: cobS guanylyltransferase: synthase: hemC cofactor biosynthesis SppA: sppA HPI: katG guanylyltransferase: nucleotidyltransferase: polyprenyltransferase: dipeptidase: 16S rRNA BVI01S_RS19355 containing protein: acetyltransferase: diphthine-- nfsA 4-amino-2-methyl-5- an oxidized phosphate an [MCD cofactor hydroxymethyltransferase: tetrahydrofolate folylpolyglutamate -C(2))- methylthiotransferase a reduced BVI01S_RS17120 pyrimidinemethanol BVI01S_RS17735 an N-acyl-(S- arsenite BVI01S_RS17735 BVI01S_RS08320 BVI01S_RS14890 BVI01S_RS01765 (cytosine(1402)-N(4) BVI01S_RS16510 BVI01S_RS12450 ammonia ligase: bifunctional thioredoxin chaperone]-MCD a holo-[hydroxymethylbilane BVI01S_RS01195 ligase: synthase/ MoO - acyl-CoA MtaB: mtaB nitroaromatic a tetrahydrofolate 2 diacyl-sn-glyceryl) a peptide an N- a diphthamide-BVI01S_RS02230 GDP cysteine synthase] molybdopterin dehydrogenase: O )-methyltransferase: (indol-3-yl)acetate compound hydroxymethylpyrimidine adenosylcobalamin 5'-phosphate BVI01S_RS08050 dihydrofolate -L-cysteinyl- 2 acetylarylamine [translation bis(molybdenum 6 bis(guanylyl a tRNA mraW Tyr an anion RS16355 an anion desulfurase: a 5,10- synthase: cofactor molybdenum cofactor BVI01S_RS15780 a 2-methylsulfanyl-N -L- 3-benzyl-3,6 - an N 4 - D- a tRNA lipoate biosynthesis kinase/ [lipoprotein] queuosine biosynthesis I (de novo) elongation lipoate salvage I cofactor) 10 37 5'-deoxyadenosine an unsulfurated molybdopterin) containing a DMKH 1402 phosphomethylpyrimidine thioredoxin- lipoate biosynthesis BVI01S_RS13985 methylenetetrahydrofolate an N - BVI01S_RS11370 guanylyltransferase: [+ 2 isozymes] threonylcarbamoyladenine met 2 bis(cysteinyl)- 6- gly methylcytidine factor 2] and incorporation I molybdenum cofactor [sulfur carrier] cofactor 3' CCA end kinase: thiD disulfide and incorporation II [+ 3 isozymes] bifunctional formyltetrahydrofolate demethylmenaquinol- BVI01S_RS17735 (2E,7Z)- in tRNA (hydroxymethyl) in 16S rRNA guanylyltransferase: a [cytidylyl molybdenum preQ -diketopiperazine 2+ 2+ HMP-P reductase: (R)-lipoate demethylmenaquinol- folylpolyglutamate bifunctional 6 biosynthesis I molybdopterin- 0 hexadecenoyl-CoA Cd CadA Cd an octanoyl-[acp] BVI01S_RS17735 a tetrahydrofolate NADPH-dependent 7- trxB lipoate-- octanoate adenosylcobalamin cofactor chaperone]- 9 biosynthesis synthase/ guanine Carbohydrate Degradation bis(guanylyl folylpolyglutamate all-trans- cyano-7-deazaguanine enoyl-CoA octanoyl bifunctional lipoate-- cytidylyl molybdenum 6 protein ligase: all-trans- dihydrofolate synthase/ 1,4-dihydroxy- dinucleotide N -(3-methylbut- all-trans- (3R,5S)-3- protein ligase: molybdopterin) hexaprenyl reductase QueF: queF hydratase: quinoxaline-2- a 2'-deoxyribonucleoside a ribonucleoside an N-hydroxy- transferase: hydroxymethylpyrimidine BVI01S_RS18575 cofactor (sulfo-dioxo) 1,4-dihydroxy- a uracil in DNA Ala propionamide phenylacetyl-CoA nonaprenyl synthase: dihydrofolate 2-naphthoate biosynthesis 2-en-1-yl)- aryl-carrier protein undecaprenyl 1,4-dihydroxy- a glycyl-[tRNA ] hydroxy-1- 2+ 2+ [(R)- BVI01S_RS18575 cofactor diphosphate preQ BVI01S_RS16190 glycogen degradation II a sulfurated [sulfur carrier] carboxyl adenylate 5'-triphosphate [DNA] 5'-monophosphate arylamine ATP Cd CadA Cd BVI01S_RS06320 kinase/ a reduced 2-naphthoate guanylylprotein B: mobB 1 ribose chitobiose degradation 37 2-naphthoate a [lipoyl-carrier protein] lipoyl]adenylate a [lipoyl-carrier protein] diphosphate BVI01S_RS11370 synthase: fructose degradation adenosine in tRNA diphosphate arylamine N- amidase domain- biotin 2-phenylacetyl- pyrroline-5- 6 phosphomethylpyrimidine enoyl-CoA bifunctional N -octanoyl-L-lysine thioredoxin N 6 -octanoyl-L-lysine BVI01S_RS11370 1,4-dihydroxy- molybdenum acetyltransferase: containing protein: CoA carboxylatepyrroline-5- base-degraded lipoate-- pyridoxal 5'-phosphate biosynthesis II a 5,10- tRNA guanosine(34) hydratase: a glycogen N,N'-diacetylchitobiose metallophosphatase/ kinase: thiD bis(guanylyl tungstenpterin) 1,4-dihydroxy- cofactor β-D-fructofuranose uracil-DNA BVI01S_RS05110 BVI01S_RS22415 epoxidase: lipoyl thiamine salvage protein ligase: lipoyl methylenetetrahydrofolate an N 10 - 2-naphthoate transglycosylase Tgt: tgt BVI01S_RS20125 β-D-ribopyranose tRNA (N6-isopentenyl DNA polymerase/ 1,4-dihydroxy- 5'-nucleotidase: D-tyrosyl-tRNA(Tyr) carboxylate cofactor biosynthesis 2-naphthoate 6'-phosphate 1-phosphate acyl carrier glycosylase: 2+ 2+ synthase: lipA polyprenyltransferase: glycogen/starch/ 3'-5' exonuclease deacylase: arylamine N- amidase domain- biotin--[acetyl-CoA- paaG paaH reductase: Cd CadA Cd HMP-PP formylaminopyrimidine BVI01S_RS18575 synthase: lipA formyltetrahydrofolate a 7-aminomethyl-7- (S)-3-hydroxy-(7Z) D-ribose 1-: adenosine(37)-C2)- protein: acpP 2-naphthoate BVI01S_RS09625 BVI01S_RS05000 aldehydo-D-ribose D-glyceraldehyde NADP polyprenyltransferase: BVI01S_RS14890 alpha-glucan PolX: polX carboxylase] ligase: paaC paaJ proC a [lipoyl-carrier a [lipoyl-carrier a [lipoyl-carrier gln 34 pyranase: methylthiotransferase polyprenyltransferase: BVI01S_RS19355 acetyltransferase: containing protein: BVI01S_RS14890 deazaguanosine in tRNA -hexadecenoyl-CoA N-monoacetylchitobiose β pfkB bifunctional 2-(1,2-epoxy-1,2- 6 6 6 5-phosphate biosynthesis : -D-fructose 1,6- uracil-DNA BVI01S_RS08315 protein]-N -[(R)- demethylmenaquinol- protein]-N -[(R protein]-N -[(R)- 3-phosphate bis(tungstenpterin) GTP rbsD MiaB: miaB [+ 8 isozymes] BVI01S_RS14890 BVI01S_RS12450 BVI01S_RS16510 dihydrophenyl) [+ 2 isozymes] S-adenosylmethionine:tRNA metallophosphatase/ 2+ 2+ menaquinol-8 biosynthesis BVI01S_RS21445 β 6'-phosphate bisphosphate a quinoxaline-2- glycosylase: an N- Hyp Co Co dihydrolipoyl]-L-lysine 8 biosynthesis I aminomethylpyrimidine )-lipoyl]-L-lysine dihydrolipoyl]-L-lysine cofactor + menaquinol-6 biosynthesis -D-ribofuranose propanoate acetyl-CoA NAD demethylmenaquinol-6 ribosyltransferase- 5'-nucleotidase: 2+ CorA 2+ 6-phospho-beta- BVI01S_RS20805 Ala acetoxyarylamine Mg Mg pyridoxal 5'- demethylmenaquinol-9 6 carboxyl-[aryl- a tRNA gly biotinyl-5'- thiaminase NAD kinase: isomerase: BVI01S_RS16900 an α-limit dextrin Secondary Metabolite Degradation N -(3-methylbut-2-en- AMP BVI01S_RS20420 1,4-dihydroxy- phosphate demethylmenaquinol-8 3-oxo-(7Z)- glucosidase: 5'-deoxyadenosine an unsulfurated carrier protein] [DNA] DMKH2-11 II: tenA molybdenum cofactor BVI01S_RS14015 1-yl)-2-(methylsulfanyl) met a ribonucleoside adenylate 2-naphthoate synthase: demethylmenaquinol-6 demethylmenaquinone tRNA preQ1(34) S- BVI01S_RS05180 [sulfur carrier] 1,4-dihydroxy- guanylyltransferase: hexadecenoyl-CoA adenosine 37 in tRNA an apyrimidinic uracil NAD kinase: demethylmenaquinone 4-amino-2-methyl-5- pdxT pdxS methyltransferase: adenosylmethionine N-acetyl-D-glucosamine anhydromuropeptides recycling I 2+ Mg 2+ 2-naphthoate BVI01S_RS17735 methyltransferase: acetyl-CoA C- D-ribofuranose site in DNA Mg MgtE pyrimidinemethanol BVI01S_RS15525 BVI01S_RS08450 ribosyltransferase- 6-phosphate polyprenyltransferase: + acyltransferase: a debranched NADP BVI01S_RS08450 menaquinol-8 isomerase QueA: queA GlcNAc-1,6- BVI01S_RS14890 bis(guanylyl BVI01S_RS09795 α-limit dextrin : β PLP menaquinol-6 anhMurNAc- all-trans- N-acetyl- -D- N-acetyl-D- 3-amino-4- a [lipoyl-carrier 34 demethylmenaquinol-8 rbsK a peptidoglycan 3-aci- a 2'-deoxyribonucleoside a [protein]- an adenosine tungstenpterin) cofactor 34 1,4-dihydroxy- a [protein]-L-lysine methylsalicylate 6 2+ 2+ an epoxyqueuosine in tRNA L-Ala-γ-D-Glu- [DNA] dodecaprenyl L-glutamine glucosaminyl-(1 galactosamine hydroxybenzoate sarcosine protein]-N -[(R) Arg2 Mg MgtE Mg (5Z)-tetradecenoyl-CoA glycogen/starch/ nitropropanoate 5'-triphosphate in [tRNA ] D-ribofuranose DAP-D-Ala diphosphate 2-naphthoate -> 4)-N-acetyl- 6-phosphate arylamine N- -dihydrolipoyl]- Flp pilus tRNA alpha-glucan Fatty Acid and Lipid Biosynthesis acyl-CoA/acyl-ACP 5-phosphate β-D-muramate acetyltransferase: L-lysine dihydrolipoyl assembly epoxyqueuosine(34) phosphorylase: N-acetylmuramoyl- nitronate dehydrogenase: N-acetylmuramoyl- DNA polymerase/ transglutaminase BVI01S_RS12450 carboxylesterase: complex D-glucopyranose L-alanine 1,4-dihydroxy- N-acetylglucosamine- dehydrogenase: + + reductase QueG: queG BVI01S_RS21445 monooxygenase: domain-containing BVI01S_RS07415 glycine oxidase Na RS20445 Na BVI01S_RS09645 trehalose degradation I (low osmolarity) L-alanine amidase 3'-5' exonuclease 2-naphthoate beta-N- 6-phosphate arylamine N- lpdA ATPase palmitate biosynthesis (type II fatty acid synthase) phosphatidylglycerol BVI01S_RS21695 protein: ThiO: thiO gondoate biosynthesis 34 amidase a [lipoyl-carrier component octanoyl-[acyl-carrier a queuosine in tRNA [+ 2 isozymes] α-D- CwlD: cwlD PolX: polX polyprenyltransferase: acetylhexosaminidase: deacetylase: nagA acetyltransferase: [+ 2 isozymes] biosynthesis I (plastidic) [+ 2 isozymes] BVI01S_RS05430 6 protein] biosynthesis (anaerobic) (2E,5Z)- α,α-trehalose CwlD: cwlD [+ 8 isozymes] BVI01S_RS14890 nagZ BVI01S_RS05110 protein]-N -[(R TadA: tadA glucopyranose ROK family 34 L-histidine biosynthesis Amino Acid Biosynthesis 3-acetylamino-4- )-lipoyl]-L-lysine an inosine + + superpathway of branched chain amino acid biosynthesis L-tryptophan biosynthesis L-methionine biosynthesis III ammonia assimilation cycle III an acetoacetyl-[acp] (mitochondria, yeast) tetradecenoyl-CoA 1-phosphate : 6-phosphate salicylate MeOH Na RS09705 Na L-lysine biosynthesis II L-arginine biosynthesis I (via L-ornithine) DHAP N-acetyl-β-D- L-alanyl-γ-D- ditrans,octacis- a peptidoglycan [unspecified a protein with an D-galactosamine hydroxybenzoate glyoxylate methylamine in [tRNA Arg2 ] a malonyl-[acp] an oleoyl-[acp] BVI01S_RS18655 acetate undecaprenyldiphospho- 3-oxopropanoate nitrite 6 γ N-acetyl-D- 6-phosphate 3-oxoacyl-[acyl- an acetoacetyl-[acp] NAD(P)H- glucosamine-1,6- glutamyl-meso-2,6- pentapeptide degradation [DNA] DMK-12 N -( -glutamyl)- GlcNAc PRPP enoyl-CoA phospho- alpha,alpha- N-acetyl-(N- muramate thr pyruvate L-homoserine ammonium carrier-protein] 3-oxoacyl-[acyl- dependent glycerol- 5-oxo-L-proline metabolism anhydro-N-acetyl- diaminopimeloyl- products] L-lysine crosslink asp glu gln hydratase: sugar mutase: phosphotrehalase: + + chorismate carrier-protein] 3-phosphate beta-ketoacyl- β-D-muramate D-alanine acetylglucosaminyl)muramate Na RS13930 Na ATP aspartate kinase: acetolactate reductase: fabG BVI01S_RS20125 BVI01S_RS16305 treC homoserine O- glu reductase: fabG dehydrogenase: a [protein] with a [protein] with (3E,5Z)-tetradeca- beta-N- phosphoribosyltransferase BVI01S_RS11555 n-acetylglutamate threonine synthase: type I [+ 2 isozymes] ACP synthase acetyltransferase: 2-oxoglutarate glutamate BVI01S_RS08490 an N-terminal an N-terminal 3,5-dienoyl-CoA enoyl-CoA acetylhexosaminidase: regulatory subunit: synthase: ammonia- ilvB ilvN anthranilate synthase glutamate- [+ 2 isozymes] II: fabF a [2-oxoglutarate- (1S,2R)-1- all-trans- all-trans- [+ 3 isozymes] synthase a (3R)-3- a (3R)-3- sn-glycerol L-glutamine L-glutamate hydratase: ROK family a sulfurated an acyl-[acyl- 1,4-dihydroxy- an alkylated DNA aci-nitroethane O-ureido-L- a carboxylic ester 3'-AMP DNA with lesion BVI01S_RS11070 L-aspartyl- BVI01S_RS05965 lyase: ilvA component I: trpE BVI01S_RS10890 -ammonia acyl-CoA nagZ γ SAM dehydrogenase ser C-(indol-3- tridecaprenyl asp retinyl palmitate Peptide RS03865 Peptide large Asp-tRNA(Asn) hydroxybutanoyl-[acp] hydroxybutanoyl-[acp] 3-phosphate BVI01S_RS16190 L-alanyl- -D- [sulfur carrier] carrier protein] dADP 4-phosphate (S)-2-acetolactate thioesterase: glucokinase: E2 protein] N 6 - yl)glycerol diphosphate 2-naphthoate homoserine excinuclease ATP bifunctional (2Z)-2-aminobut- O-acetyl-L- /Glu-tRNA(Gln) ligase: glnA an (11Z)-3-oxo- 1,6-anhydro-N- glutamyl-meso- bifunctional 2',3'- subunit: gltB 3-hydroxyacyl- 3-hydroxyacyl- glycerol-3- BVI01S_RS05030 BVI01S_RS18655 β ABC: uvrB uvrA phosphoribosyltransferase: 2-enoate homoserine hydrogen sulfide icos-11-enoyl-[acp] D-glucopyranose D-glucopyranose acetyl- -muramate diaminopimelate octanoyl-L-lysine 3-phosphate cyclic-nucleotide 2'- ribonucleotide- aspartate- ornithine ketol-acid anthranilate PRPP amidotransferase: ACP dehydratase ACP dehydratase phosphate 1-O- (S)-3-hydroxy-(5Z) D-glucopyranose DNA-3- nitronate BVI01S_RS11075 [+ 5 isozymes] 6-phosphate 6-phosphate anhydro-N- phosphate 1,4-dihydroxy- argininosuccinate carboxylesterase: carboxylesterase: phosphodiesterase/ excinuclease diphosphate semialdehyde acetyltransferase/ reductoisomerase: BVI01S_RS12380 FabZ: fabZ a [protein] with -tetradecenoyl-CoA lipoyl tryptophan methyladenine monooxygenase: Peptide RS15430 Peptide FabZ: fabZ acyltransferase 3-oxoacyl-ACP γ (3E,5Z)- acyltransferase 2-naphthoate synthase: BVI01S_RS07415 BVI01S_RS07415 3'-nucleotidase: ABC subunit reductase: 1-(5-phospho- dehydrogenase: N-acetylglutamate ilvC O-acetylhomoserine ammoniumBVI01S_RS12385 gln an N-terminal 5- -L-glutamyl acetylmuramic synthase: trpB glycosylase: BVI01S_RS21695 anthranilate PlsY: plsY reductase glutathione tetradecadienoate synthase: BVI01S_RS01500 UvrC: uvrC BVI01S_RS17115 β-D-ribosyl)-ATP synthase: argJ (2R)-2,3- gatC gatA gatB 5-phosphate acid kinase: PlsX: plsX polyprenyltransferase: BVI01S_RS14065 asd phosphoribosyltransferase: trpD aminocarboxypropyltransferase/ a (2E)-but-2-enoyl-[acp] a (2E)-but-2-enoyl-[acp] a 1-acyl-sn FabG: fabG oxo-L-proline lipA BVI01S_RS20280 BVI01S_RS19275 [+ 2 isozymes] DNA without BVI01S_RS17120 2-iminobutanoate BVI01S_RS05220 N-acetylglucosamine BVI01S_RS14890 bifunctional dihydroxy-3- cysteine synthase: [+ 11 isozymes] -glycerol 3- adenosine lesion ADP L-aspartate 4- N-acetyl-L- 3-oxoacyl-[acyl- C1 Compound Utilization and Assimilation N-acetyl-D- an alcohol a carboxylate palmitate a retinol Peptide Peptide methylbutanoate BVI01S_RS10885 enoyl-ACP enoyl-[acyl- phosphate 3-oxo-(5Z)- degradation I a [2-oxoglutarate D-glyceraldehyde a DNA containing RS17075 phosphoribosyl- semialdehyde glutamate carrier-protein] 5'-deoxyadenosine an unsulfurated an alkylated canavaninosuccinate dihydroxy-acid N-(5-phosphoribosyl)-anthranilate reductase carrier-protein] 1-acyl-sn-glycerol- tetradecenoyl-CoA muramate 6- N-acetyl-D- met dehydrogenase acyl-carrier protein an acyl phosphate 3-phosphate trp acetaldehyde nitrite AMP cyclohydrolase/ reductase: fabG [sulfur carrier] nucleobase an apurinic/ 4-hydroxy- uracil degradation reductase acetyl-CoA C- formate assimilation into 5,10- phosphate E2 protein] N 6 DMKH2-13 phosphoribosyl- acetylglutamate dehydratase: FabI: fabI 3-phosphate formaldehyde glucosamine apyrimidinic site tetrahydrodipicolinate phosphoribosylanthranilate L-homocysteine glu I (reductive) FabL: fabL a (3R,11Z)-3-hydroxy- 5-oxo-L-proline acyltransferase: methylenetetrahydrofolate N-acetylmuramic -lipoyl-L-lysine ATP diphosphatase kinase: argB ilvD acyltransferase: oxidation II 6-phosphateN-acetylglucosamine- Peptide RS20625 Peptide synthase: dapA 2-oxobutanoate isomerase: BVI01S_RS20270 a butanoyl-[acp] icos-11-enoyl-[acp] BVI01S_RS09795 acid 6- HisIE: 3-methyl-2- uracil [+ 2 isozymes] BVI01S_RS08525 5-oxoprolinase (glutathione-dependent) 6-phosphate (2S,4S)-4- N-acetylglutamyl- methionine methionine a 1,2-diacyl- formate phosphate 1-(2-carboxyphenylamino)-1- 3-hydroxyacyl- (3Z)-dodec- 1939 BVI01S_RS11105 acetolactate oxobutanoate dihydropyrimidine subunit PxpA: D-glucosaminedeacetylase: nagA a 5-methylaminomethyl- 34 a thiocarboxylated all-trans- methyl β-D-glucoside a uracil a double hydroxy-2,3,4,5- phosphate synthase: synthase: beta-ketoacyl- sn-glycerol formate--tetrahydrofolate formaldehyde etherase: murQ geranyl a uridine a peptide with a a [DNA]-3'- a 5'-phospho- synthase: deoxy-D-ribulose 5-phosphate a butanoyl-[acp] ACP dehydratase 3-enoyl-CoA 2-thiouridine 34 [SAMP] C- DL-allothreonine decaprenyl 1,4-dihydroxy- H O 3'-GMP 5-MTR-1-P 1-(5-phospho-β- tetrahydrodipicolinate L-arginine biosynthesis II (acetyl cycle) dehydrogenase: preA BVI01S_RS08950 N-acetyl-D- 6-phosphate selenophosphate in tRNA 2 ATP 6-phosphate hydroxyl [DNA] in 23S rRNA stranded DNA N-acetyl-gamma- metH metH ACP synthase 3-phosphate ∆ ∆ ligase: BVI01S_RS08050 diphosphate 2-naphthoate leader sequence a sugar RS02855 a sugar D-ribosyl)-AMP 4-hydroxy- ilvB ilvN 2-isopropylmalate branched-chain- indole-3-glycerol phosphate FabZ: fabZ 5-oxoprolinase 3, 2-enoyl- glucosamine in tRNA terminal glycine diphosphate 23S rRNA bifunctional 2',3'- DNA: S-methyl-5- 5,6-dihydrouracil II: fabF beta-ketoacyl- phosphatidate an N 10 -formyltetrahydrofolate glutamyl-phosphate (S)-2-aceto-2- synthase: amino-acid CoA isomerase: 6-phosphate (uracil(1939)-C(5)) cyclic-nucleotide 2'- gyrA gyrB thioribose-1- bifunctional tetrahydrodipicolinate N-acetylglutamyl- synthase TrpC: trpC met ACP synthase cytidylyltransferase: a (2E,11Z)-icosa- subunit S-(hydroxymethyl) 6-phospho-beta- reductase: hydroxybutanoate BVI01S_RS09910 transaminase: BVI01S_RS20125 N-acetylglucosamine- tRNA 2- serine DNA ligase D: -methyltransferase phosphodiesterase/ DNA phosphate phosphoribosyl- reductase: phosphate : a 3-oxohexanoyl-[acp] II: fabF BVI01S_RS03170 2,11-dienoyl-[acp] PxpB: pxpB bifunctional 5,10- glutathione α tRNA 2- 1,4-dihydroxy- signal nucleoside glucosidase: hydrogencarbonate BVI01S_RS12360 ilvE -D-glucosamine thiouridine(34) hydroxymethyltransferase: BVI01S_RS15140 RlmD: rlmD topoisomerase a sugar RS05505 a sugar BVI01S_RS08340 ketol-acid (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate hydA (2E)-dodec- 6-phosphate selenouridine(34) 2-naphthoate peptidase I: lepB BVI01S_RS05180 3'-nucleotidase: isomerase: AMP cyclohydrolase/ N-acetyl-L- phosphatidate enoyl-ACP methylene-tetrahydrofolate glutathione- 6-phosphate synthase triphosphatase reductoisomerase: (2S)-2- 3-oxoacyl-[acyl- glu 2-enoyl-CoA deacetylase: nagA synthase BVI01S_RS01195 polyprenyltransferase: [+ 5 isozymes] [+ 2 isozymes] BVI01S_RS01500 IV: parC parE mtnA phosphoribosyl- (S)-2,3,4,5- carbamoyl glutamate 5- a 3-oxohexanoyl-[acp] cytidylyltransferase: reductase dehydrogenase/5,10- dependent YtkD: ytkD a 5- a negatively S-methyl-5- isopropylmalate 3-ureidopropanoate glucosamine- MnmA: mnmA 1939 ATP diphosphatase tetrahydrodipicolinate phosphate synthase: semialdehyde ilvC tryptophan synthase: carrier-protein] FabI: fabI enoyl-CoA methylene-tetrahydrofolate formaldehyde D-glucosamine MnmH: mnmH BVI01S_RS14890 methyluracil thio-D-ribulose 3-isopropylmalate val BVI01S_RS09300 6-phosphate β-D-glucose guanosine supercoiled DNA acetylornithine (R)-2,3-dihydroxy- trpB BVI01S_RS20280 reductase: fabG 3-oxoacyl-[acyl- hydratase: 6-phosphate MeOH [DNA] in 23S rRNA 1-phosphate a sugar RS16455 a sugar HisIE: 2,3,4,5- BVI01S_RS12380 L-tyrosine biosynthesis I cyclohydrolase: dehydrogenase: + dehydratase: β-ureidopropionase: a CDP- deaminase: a [SAMP] C- a 2-thiouridine 34 acetaldehyde ADP H 6-phosphate transaminase: 3-methylpentanoate [+ 2 isozymes] carrier-protein] a gondoyl-[acp] BVI01S_RS16190 BVI01S_RS16890 BVI01S_RS05830 phosphoglucosamine a 5-methylaminomethyl- (2E)-3,7- gly a peptide phosphate BVI01S_RS11105 tetrahydropyridine- BVI01S_RS12385 N-acetyl-gamma- ser diacylglycerol nagB a leader sequence β BVI01S_RS12375 leuC leuD indole BVI01S_RS14525 reductase: fabG mutase: 2-selenouridine 34 dimethylocta- terminal glycine in tRNA DMKH2-10 1-(5-phospho- -D-ribosyl)- 2,6-dicarboxylate N- glutamyl-phosphate dihydroxy-acid a (3R)-3- enoyl-CoA bifunctional glutamine- chorismate L-selenocysteine [+ 2 isozymes] CDP-diacylglycerol-- periplasmic disulfide bond formation glutathione- in tRNA 2,6-diene-1-thiol 5-[(5-phosphoribosylamino) acetyltransferase: reductase: dehydratase: 2-isopropylmaleate hydroxyhexanoyl-[acp] hydratase: BVI01S_RS19245 F6P hydrolyzing N-acetyl-L- biosynthesis I (bacteria) β-alanine glycerol-3-phosphate 3- methylenetetrahydrofolate dependent a sugar RS05650 a sugar methylideneamino]imidazole- dapD BVI01S_RS12360 ilvD tryptophan synthase: bifunctional 3-deoxy-7- a (3R)-3- BVI01S_RS20125 α-D-glucosamine carbamoyl- ornithine acetylglutamate 3-hydroxyacyl- phosphatidyltransferase: a [DsbB protein] a [DsbA protein] two reduced dehydrogenase/ formaldehyde 4-carboxamide 3-isopropylmalate phosphoheptulonate an electron- 1-phosphate kinase: argB (3S)-3-methyl-2- trpB BVI01S_RS20280 hydroxyhexanoyl-[acp] cysteine residues (S)-3- methenyltetrahydrofolate 2-hydroxy-5- 2251 an unstable phosphate sec ACP dehydratase pgsA with reduced L- carrying a dehydrogenase: 54 a 5,10- an (R)-2- guanosine a supercoiled L-2-acetamido-6- dehydratase: synthase/ selenide ser a tRNA transfer quinone a uracil in tRNA 3-methylbutanoate a D-aminoacyl- leukotriene-D4 DHAP a phosphate 1-(5-phosphoribosyl)-5- N-acetyl-L- oxopentanoate fatty acid biosynthesis disulfide bond in a protein hydroxydodecanoyl-CoA cyclohydrolase FolD: folD bifunctional UDP-N- methylenetetrahydrofolate glycerophosphoglycerol (methylsulfanyl) duplex DNA RecA filament- oxoheptanedioate synthase: gln N-acetyl-L- chorismate mutase: FabZ: fabZ 3-hydroxyacyl- 1-(3-sn- cysteine residues BVI01S_RS00765 halocarboxylate [tRNA] in 23S rRNA monoester a sugar RS12030 a sugar [(5- phosphoribosylamino) glu glutamate 5- leuC leuD initiation (type II) -3-oxopent-1- 23S rRNA NAD(P)H- replicative DNA complex carB carA glutamate branched-chain- BVI01S_RS21200 selenide, ACP dehydratase phosphatidyl) acetylglucosamine alkaline DNA methylideneamino]imidazole-4- n-acetylglutamate semialdehyde (2R,3S)-3- trp a 5,10-methenyltetrahydrofolate S-formylglutathione enyl 1-phosphate (guanosine(2251) dependent glycerol- DNA amino-acid water serine--tRNA a (2E)-hex-2-enoyl-[acp] FabZ: fabZ -sn-glycerol diphosphorylase/ mannitol 2-hydroxy-3-keto-5- phosphatase: repair carboxamide isomerase: hisA carbamoyl synthase:carbamoyl acetylornithine isopropylmalate chorismate acetyl-CoA FADH(2)-oxidizing acetate--CoA HAD family glycerophosphodiester membrane -2'-O)- 3-phosphate : L-ornithine transaminase: dikinase glycine ligase: serS L-threonine 3-phosphate glucosamine-1- degradation I D-tyrosyl-tRNA(Tyr) methylthiopentenyl- BVI01S_RS01420 protein phosphate BVI01S_RS05965phosphate synthase: transaminase: mutase: aroH acetyl-CoA bifunctional 5,10- methylenetetrahydrofolate- hydrolase: phosphodiesterase: dipeptidase: phosphoribulosylformimino- ilvE 3-isopropylmalate SelD:biosynthesis selD IV enoyl-ACP a (2E)-hex-2-enoyl-[acp] phosphatidylglycerophosphatase 3-oxododecanoyl-CoA phosphate N- ligase: acsA deacylase: 1- phosphate methyltransferase dehydrogenase: dnaB RecO: a sugar RS06120 a sugar N-acetyl-L,L-2,6- BVI01S_RS12380 prephenate biosynthesis carboxylase methylene-tetrahydrofolate D-mannitol -tRNA-(uracil(54)-C(5) BVI01S_RS14170 BVI01S_RS06480 BVI01S_RS01765 alkaline bifunctional BVI01S_RS12375 dehydrogenase: reductase phosphatase: RlmB: rlmB BVI01S_RS08490 [+ 4 isozymes] AICAR-phosphate diaminopimelate n-acetylglutamate A: BVI01S_RS15635 acetyltransferase )- methyltransferase BVI01S_RS19355 2-O- phosphatase: a stabilizedrecO ornithine ornithineBVI01S_RS12385 leuB selenophosphate an L-seryl-[tRNA sec ] FabI: fabI enoyl-[acyl- carboxyltransferase acetyl-CoA C- dehydrogenase/5,10- 1-phosphate [+ 5 isozymes] [+ 3 isozymes] 1,2-dihydroxy-5-BVI01S_RS10475 sn-glycerol a single synthase: ile prephenate thr phosphatidylglycerophosphatase GlmU: glmU mannitol-1- methylguanosine 2251 BVI01S_RS07035 RecA filament- N-acetyldiaminopimelate carbamoyltransferase: acetyltransferase/ L-homoserine carrier-protein] subunit beta: acyltransferase: methylene-tetrahydrofolate formate TrmFO: trmFO (methylsulfanyl) 3-phosphate stranded DNA imidazole glutamine- BVI01S_RS05965 (2S)-2-isopropyl- L-citrulline biosynthesis superpathway of L-serine dehydrogenase: A: BVI01S_RS13700 formate N-acetyl-α-D- phosphate 5- 3-methylbutanoyl-CoA diphosphate deacetylase: argF N-acetylglutamate : a hexanoyl-[acp] BVI01S_RS04070 BVI01S_RS09795 cyclohydrolase: AMP an uncharged leukotriene-E4 gly in 23S rRNA an alcohol DNA complex predicted hydrolyzing 3-oxosuccinate BVI01S_RS08410 : reductase an L-1- oxidation to CO glucosamine dehydrogenase: an (S)-2- pent-1-en-3-one glycerol BVI01S_RS10685 bifunctional and glycine biosynthesis I BVI01S_RS04990 2 glycerol sn-glycerol a D-amino acid ABC synthase: argJ L-seryl-tRNA(Sec) malonyl-CoA BVI01S_RS16890 54 a halide anion tRNA carbamoyl- 3-(4- BVI01S_RS09945 FabL: fabL phosphatidyl- 1-phosphate BVI01S_RS10210 a 5-methyluracil hydroxycarboxylate 3-phosphate a sugar a sugar phosphate ornithine beta-ketoacyl- decanoyl-CoA a tetrahydrofolate transporter L,L- phosphate gln 3-phospho- hydroxyphenyl) gly selenium O-phospho- [+ 2 isozymes] sn-glycerol bifunctional formate F6P in tRNA synthase: asp L-citrulline acetyltransferase/ ACP synthase ACP S- bifunctional UDP-N- of a sugar diaminopimelate synthase: L-isoleucine D-glyceratephosphoglycerate pyruvate transferase: L-homoserine acyl-CoA methylenetetrahydrofolate formate hisH hisF N-acetylglutamate Asp-tRNA(Asn) II: fabF malonyltransferase: acetylglucosamine L-proline carB carA N-acetyl-L- biosynthesis IV 4-methyl-2- dehydrogenase: tyrosine BVI01S_RS03515 a hexanoyl-[acp] DsbA family dehydrogenase: dehydrogenase/ dehydrogenase diaminopimelate synthase: argJ threonine synthase: fabD diphosphorylase/ an [amino-group carrier predicted ornithine L-homoserine oxopentanoate /Glu-tRNA(Gln) aminotransferase: BVI01S_RS15780 methenyltetrahydrofolate subunit alpha: fdhF O-acetyl-L- an (S)-2- sn-glycero-3- lysine within a monocarboxylic a large- hydrogen D-erythro-1- epimerase: argininosuccinate biosynthesis I carbamoyl BVI01S_RS10990 BVI01S_RS09940 a 3-oxooctanoyl-[acp] oxidoreductase: glucosamine-1- methanethiol 2-methylbutanoate 2-oxoglutarate (R)-lipoate protein]-C-terminal-γ- A(H2) AICAR L-ornithine propanoate biosynthesis branched-chain- amidotransferase: BVI01S_RS08280 beta-ketoacyl- cyclohydrolase FolD: folD CO halocarboxylate phosphoethanolamine D-ala gcv protein H acid amide branched glucan peroxide a protein GMP ABC (imidazol-4- (from L-glutamate) phosphate 3-phosphooxypyruvate an L-selenocysteinyl- a malonyl-[acp] BVI01S_RS03120 [+ 2 isozymes] 2 homoserine a sugar a sugar BVI01S_RS15135 synthase: BVI01S_RS12380 ACP synthase a [DsbB protein] a [DsbA protein] phosphate N- amidase domain- (L-glutamyl)-L-glutamate type I transporter yl)-glycerol long-chain-fatty- amino-acid [tRNA sec ] an electron- an intra- BVI01S_RS14065 thr 3-oxoacyl-[acyl- carrying a with reduced L- a 5,10-methylenetetrahydrofolate acetyltransferase containing protein: pullulanase: GPR of a sugar meso- glu acid--CoA ligase: asp transaminase: BVI01S_RS12385 3-phosphoserine/ tyr II: fabF ketoacyl-ACP transfer quinol protein disulfide (2E)-dec-2-enoyl-CoA acetylglutamate catalase/ GMP 3-phosphate carrier-protein] disulfide bond cysteine residues GlmU: glmU O-acetylhomoserine acetate--CoA HAD family glycerophosphodiester lipoate-- BVI01S_RS22415 pulA endopeptidase: diaminopimelate glutamate 5- BVI01S_RS07045 aspartate kinase: ilvE gatC gatA gatB phosphohydroxythreonine synthase III: D-amino-acid kinase: argB peroxidase reductase: imidazoleglycerol- L-arginino- reductase: fabG a 3-oxooctanoyl-[acp] enoyl-CoA aminocarboxypropyltransferase/ hydrolase: phosphodiesterase: protein ligase: BVI01S_RS17845 [+ 5 isozymes] [+ 11 isozymes] transaminase: serC UDP-N-acetyl- ligase: acsA transaminase: amidase domain- an [amino-group carrier pullulanase: guaC predicted phosphate diaminopimelate succinate kinase: proB BVI01S_RS11555 BVI01S_RS18255 BVI01S_RS14170 BVI01S_RS06080 BVI01S_RS18575 HPI: katG γ-L-glutamyl [+ 2 isozymes] hydratase: α-D-glucosamine cysteine synthase: dat containing protein: BVI01S_RS01990 ABC dehydratase decarboxylase: lysA propanoyl-CoA [+ 3 isozymes] leu O-phospho- protein]-C-terminal- a long-linear a peptide a sugar a sugar L-aspartyl- 3-oxoacyl-[acyl- BVI01S_RS16190 UDP-N-acetylglucosamine BVI01S_RS10885 [+ 5 isozymes] [+ 3 isozymes] BVI01S_RS16510 IMP transporter diaminopimelate argininosuccinate 5-phosphate glu L-cysteine biosynthesis I a (3R)-3- an acetoacetyl-[acp] γ-(5-phospho-L- HisB: hisB L-serine carrier-protein] N 6 -L-threonylcarbamoyladenosine 37 (2S)-2- a [glycine-cleavage α-D-glucan 3-(imidazol-4- lyase: argH ornithine 2-oxoacid:ferredoxin 4-phosphate hydroxyoctanoyl-[acp] enoyl-CoA 1-carboxyvinyltransferase: a monocarboxylate glutamyl)-L-glutamate of a sugar decarboxylase: lysA glutamate-5- reductase: fabG methylbutanoyl-CoA diphosphate 6 A H O oxidoreductase phosphoserine -modified tRNA biosynthesis AMP pyruvate complex H protein] N 2 yl)-2-oxopropyl semialdehyde carbamoyltransferase: glutamate hydratase: BVI01S_RS15845 acetate an (S)-2- sn-glycerol D-glt subunit beta: aspartate- phosphatase: 3-hydroxyacyl- [+ 2 isozymes] met a halide anion ethanolamine -[(R)-lipoyl]-L-lysine sulfate RS14545 sulfate phosphate lys arg dehydrogenase: argF pro 5-kinase: L-arginine ser BVI01S_RS20125 UDP-N-acetylglucosamine hydroxycarboxylate 3-phosphate BVI01S_RS09535 semialdehyde BVI01S_RS17160 ACP dehydratase histidinol-phosphate BVI01S_RS08655 proB degradation I a (3R)-3- thr (S)-3- 1-carboxyvinyltransferase: dehydrogenase: serine O- FabZ: fabZ transaminase: proline γ-L-glutamyl (arginase pathway) hydroxyoctanoyl-[acp] phosphatidylserine and threonylcarbamoyl- hydroxydecanoyl-CoA murA L- L-glutamate-5- 2-oxobutanoate asd ser acetyltransferase: BVI01S_RS09865 dehydrogenase: 5-phosphate AMP synthase: α adenine 2503 a [lipoyl-carrier acibenzolar- a double-stranded a mismatched biosynthesis I a (2E)-oct-2-enoyl-[acp] 3-hydroxyacyl- phosphatidylethanolamine UDP-N-acetyl- - acetoacetate 1,4-dihydroxy- carbamoyl an L-aspartyl- carbonic acid sulfite RS05415 sulfite semialdehyde L-aspartate 4- BVI01S_RS06955 arg cysE BVI01S_RS01165 isobutanoate succinyl-CoA GGPP L-ornithine (R)-lipoate repressor LexA histidinol-phosphate acetolactate serine ACP dehydratase biosynthesis I (L-threonylcarbamoyl) Alcohol Degradation D-glucosamine- in 23S rRNA protein]-L-lysine S-methyl oligonucleotide [tRNA Asn ] DNA semialdehyde stearate biosynthesis 2-naphthoate phosphate bifunctional transaminase: L-asparagine synthase: ilvB ilvN (S)-1-pyrroline- hydroxymethyltransferase: arginase: enoyl-ACP FabZ: fabZ adenylate enolpyruvate Asp-tRNA(Asn) DNA chorismate glutamate-5- O-acetyl-L-serine II (bacteria and plants) a CDP-diacylglycerol oligoribonuclease/ transcriptional BVI01S_RS08415 biosynthesis I homoserine 5-carboxylate rocF hydrogen sulfide reductase /Glu-tRNA(Gln) mismatch bifunctional 3-deoxy-7- L-citrulline (S)-2-aceto-2- semialdehyde BVI01S_RS01195 CDP-diacylglycerol--serine tRNA (adenosine(37)-N6)- 3-oxodecanoyl-CoA glycerol and glycerophosphodiester degradation UDP-N- 23S rRNA 3-oxoacid CoA- lipoate-- carbonic repressor acetate acetate dehydrogenase: FabI: fabI a (2E)-oct-2-enoyl-[acp] glycerol degradation V acetate--CoA 1,4-dihydroxy- ornithine carboxylesterase: PAP phosphatase repair phosphoheptulonate dehydrogenase: L-ornithine threonylcarbamoyltransferase acetylmuramate transferase amidotransferase: anhydrase: RS01330 L-histidinol (S)-1-pyrroline- hydroxybutanoate O-phosphatidyltransferase: acetyl-CoA C- (adenine(2503)-C(2) protein ligase: BVI01S_RS07415 NrnA: LexA: lexA protein asp BVI01S_RS09935 BVI01S_RS08655 gly a palmitoyl-[acp] complex: tsaE tsaB tsaD dehydrogenase: ligase: acsA 2-naphthoate carbamoyltransferase: gatC gatA gatB a metal a metal phosphate synthase/ 5-carboxylate argininosuccinate 2-aceto-2-hydroxy- O-acetylhomoserine pssA glycerol )-methyltransferase subunit B: BVI01S_RS18575 BVI01S_RS04890 BVI01S_RS12185 homoserine ornithine--oxo-acid an octanoyl-[acp] enoyl-[acyl- beta-ketoacyl- an N 6 -L- acyltransferase: glycerol polyprenyltransferase: argF an L-asparaginyl- cleaved MutS: mutS chorismate mutase: asparagine murB RlmN: rlmN BVI01S_RS21395 Asn a properly cation cation pyrroline-5- synthase: butanoate aminocarboxypropyltransferase/ CDP-diacylglycerol--serine 37 a nucleoside 5'- [tRNA ] repressor LexA histidinol- synthase dehydrogenase: transaminase: carrier-protein] ACP synthase threonylcarbamoyladenine BVI01S_RS09795 BVI01S_RS14890 matched BVI01S_RS21200 carboxylate BVI01S_RS14065 isomeroreductase: L-glutamate-5- cysteine synthase: beta-ketoacyl- O-phosphatidyltransferase: UDP-N-acetyl- a [lipoyl-carrier monophosphate phosphatase BVI01S_RS07250 BVI01S_RS13965 reductase II: fabF in tRNA α isobutanoyl-CoA acibenzolar MeOH (glutamine- a 3-oxooctadecanoyl- octanoyl-CoA -D-muramate diphosphate 6 CO H O DNA base pair HisJ: hisJ chorismate reductase: L-arginino- ilvC semialdehyde BVI01S_RS10885 ACP synthase FabL: fabL pssA a glycerophosphodiester a 2-methyladenine 2503 AMP protein]-N -[(R 2 2 hydrolyzing) arg L-glutamate-5- [acp] a 3-sn-phosphatidyl- dihydroxyacetone 5'-deoxyadenosine acetoacetyl-CoA succinate L-citrulline mutase: aroH proC succinate [+ 2 isozymes] II: fabF met demethylmenaquinol-4 )-lipoyl]-L-lysine : asnB (R)-2,3-dihydroxy- L-homoserine [+ 2 isozymes] L-serine acyl-CoA glycerol in 23S rRNA histidinol prephenate semialdehyde 3-oxoacyl- dihydroxyacetone [+ 2 isozymes] argininosuccinate 3-methylpentanoate ornithine--oxo-acid phosphatidylserine dehydrogenase: glycerophosphodiester asparagine transaminase: arginase: L-glutamate a 3-oxodecanoyl-[acp] an octanoyl-[acp] [acyl-carrier- kinase subunit UDP-N-acetyl- histidinol prephenate lyase: argH dihydroxy-acid L-alanine cys decarboxylase: Pentose Phosphate BVI01S_RS15780 glycerol phosphodiesterase: synthase pro BVI01S_RS13965 gamma- protein] DhaK: dhaK α-D-muramoyl- dehydrogenase: dehydratase: dehydratase: ilvD biosynthesis III rocF BVI01S_RS02160 Pathways [+ 2 isozymes] kinase BVI01S_RS06080 a 2-oxo a peptide with a (1->4)- a uridine 38- (glutamine- 3-oxoacyl-[acyl- reductase: γ succinyl-CoA an (S)-2- chitin an L-glutamyl- a [protein]- hisD pheA alanine semialdehyde L-alanyl- -D- 5-aminolevulinate a 3-oxoacid an N-terminal α-D-glucan pyrazinamide ser arg carrier-protein] an L-1- GlpK: glpK [+ 3 isozymes] DHAP carboxylate halocarboxylate 40 in tRNA [tRNA Gln ] L-histidine hydrolyzing) (3S)-3-methyl-2- dehydrogenase: fabG (2E)-oct-2-enoyl-CoA glutamyl-meso-2,6- RluA family 3-phenyl-2- cys racemization pentose phosphate Xaa-L-proline Asp-tRNA(Asn) amidase domain- : L-serine histidinal : asnB oxopentanoate L-ornithine pruA reductase: fabG [+ 2 isozymes] phosphatidylethanolamine Fermentation homolactic fermentation diaminopimelate cysteine pathway beta-N- pseudouridine /Glu-tRNA(Gln) containing protein: BVI01S_RS02840 a short a short oxopropanoate asn branched-chain- [+ 2 isozymes] a (3R)-3- enoyl-CoA sn-glycerol 2-oxoacid:ferredoxin 3-oxoacid CoA- HAD family alpha-glucosidase: ammonia-lyase, desulfurase: acyl-CoA hydrolysis (oxidative branch) I acyl--CoA ligase: leucyl synthase: BVI01S_RS22415 chain RS16955 chain histidinol phenylalanine ornithine ala glu hydroxyoctadecanoyl- hydratase: 3-phosphate oxidoreductase transferase BVI01S_RS17785 acetylhexosaminidase: amidotransferase: [+ 2 isozymes] iron-sulfur- amino-acid a (3R)-3- D-glucopyranose D-glucopyranose BVI01S_RS14000 hydrolase: BVI01S_RS07780 a [protein]- dehydrogenase: transaminase: BVI01S_RS13985 alanine racemase: aminopeptidase: nagZ gatC gatA gatB amidase domain- dependent: fatty acid fatty acid transaminase: ilvE carbamoyltransferase: hydroxydecanoyl-[acp] a 2,3,4-saturated [acp] 6-phosphate BVI01S_RS16190 subunit beta: subunit B: BVI01S_RS14170 alpha-glucosidase: an L-glutaminyl- N-phospho- hisD BVI01S_RS08280 [+ 3 isozymes] glucose-6- BVI01S_RS13795 [+ 3 isozymes] containing protein: sdaAA sdaAB argF BVI01S_RS17190 3-hydroxyacyl- long-chain fatty ROK family enoyl-CoA BVI01S_RS09535 BVI01S_RS21395 [+ 6 isozymes] BVI01S_RS16290 a pseudouridine 38- Gln ala 3-hydroxyacyl- fatty acyl CoA [tRNA ] BVI01S_RS16510 L-histidine ile acyl-CoA ACP glucokinase: phosphate N-acetyl-D- pyruvate D-ala ACP dehydratase acid activation hydratase: 5-aminolevulinyl- chitin 40 in tRNA pyrazine-2- a purine RS03380 a purine his phe L-citrulline thioesterase: dehydratase dehydrogenase: diphosphate a peptide with glucosamine BVI01S_RS18655 BVI01S_RS20125 DHAP a reduced AMP CoA a proteinogenic a (1->4)- carboxylate FabZ: fabZ a long-chain + a 2,3,4-saturated a (2R)-2- D-glucopyranose BVI01S_RS05030 FabZ: fabZ 6-phosphoBVI01S_RS06620 an acyl-CoA CO H succinate a halide anion an N-terminal α-D-glucan D-glucopyranose (S)-3- 2 ferredoxin [iron- 3-oxoacyl-CoA hydroxy fatty acid amino acid [+ 5 isozymes] fatty acid D-glucono- L-proline a (2E)-dec-2-enoyl-[acp] a 2,3,4-saturated a (2E)-octadec- acyl--CoA ligase: 6-phosphate hydroxyoctanoyl-CoA sulfur] cluster 1,5-lactone predicted fatty acid 2-enoyl-[acp] BVI01S_RS14000 glucose-6- [+ 5 isozymes] ABC efflux Nucleoside and Nucleotide Biosynthesis enoyl-ACP enoyl-ACP a long-chain phosphate a ring-opened 7- 34 5-(methylsulfanyl) S-methyl-5- a 2-oxo a [protein]-S- a uridine an (R)-2- a D-tryptophanyl- (R)-N-formyl-β- a uracil 1498 dCDP thiol transporter thiol reductase reductase fatty acyl-CoA isomerase: methylguanine L-ornithine -2,3-dioxopentyl thio-D-ribulose acrylamide roseoflavin carboxylate sulfanyl-L-cysteine in tRNA halocarboxylate [tRNA Trp ] hydroxy-L-kynurenine in 16S rRNA ribonucleotide- of a thiol FabI: fabI FabI: fabI BVI01S_RS20205 D-gluconate 3-oxooctanoyl-CoA in DNA 1-phosphate 1-phosphate 16S rRNA amidase domain- bifunctional UMP biosynthesis III 2,3-diketo-5- methylthioribulose diphosphate group superpathway of guanosine superpathway of inosine-5'-phosphate biosynthesis I xanthine and adenine and pyrimidine deoxyribonucleotides de novo biosynthesis I purine deoxyribonucleosides salvage 6-phosphate (uracil(1498)-N(3))- containing protein: riboflavin a decanoyl-[acyl-carrier protein] F6P methylthiopentyl-1- 1-phosphate reductase: nucleotides de novo biosynthesis I adenosine nucleotides xanthosine salvage adenosine salvage III a stearoyl-[acp] NADP-dependent acetyl-CoA C- ornithine--oxo-acid tRNA 2- HAD family arylformamidase: methyltransferase: BVI01S_RS22415 kinase/FAD DNA- D-tyrosyl-tRNA(Tyr) phosphate enolase: dehydratase: BVI01S_RS17115 gln de novo biosynthesis I UDP CTP phosphogluconate acyltransferase: transaminase: thiouridine(34) hydrolase: kynB BVI01S_RS17795 synthetase: hydrogencarbonate AIR beta-ketoacyl- 6-phosphofructokinase: formamidopyrimidine deacylase: BVI01S_RS10470 5-(methylsulfanyl)BVI01S_RS10480 an N 3 - amidase domain- BVI01S_RS17120 ribonucleotide- nucleoside 2'-deoxyguanosine 2'-deoxyadenosine dehydrogenase: gndA BVI01S_RS09795 BVI01S_RS13965 synthase BVI01S_RS14170 2-hydroxy-5- ribF 5-(carboxyamino) adenine glycosylase: mutM BVI01S_RS19355 -2,3-dioxopentyl methyluracil 1498 containing protein: IMP xanthosine diphosphate reductase: triphosphatase ACP synthase pfkA MnmA: mnmA [+ 5 isozymes] (methylsulfanyl) CDP IMP deoxynucleoside deoxynucleoside NADP-dependent hexanoyl-CoA BVI01S_RS16510 roseoflavin asp imidazole ribonucleotide purine-nucleoside BVI01S_RS17115 YtkD: ytkD II: fabF β-D-fructose 1,6- -3-oxopent-1- 1-phosphate in 16S rRNA carbamoyl purine-nucleoside kinase: kinase: phosphogluconate (R)-β-hydroxy- formate 5'-phosphate IMP synthase: purK phosphorylase: deoD BVI01S_RS17120 CDP a [DNA]- 2,6-diamino-4- a proteinogenic L-glutamate-5- enyl 1-phosphate acrylate phosphate synthase: phosphorylase: deoD BVI01S_RS21510 BVI01S_RS21510 stearate bisphosphate a 5'-phospho- 34 dehydrogenase: gndA acyl-CoA 4-oxo-2-pentenal a [protein]- a 2-thiouridine a (2R)-2- Trp L-kynurenine dehydrogenase: N5-CAIR purine-nucleoside dUDP a 3-oxododecanoyl-[acp] nucleotide- [DNA] hydroxy-5-(N-methyl) amino acid semialdehyde a halide anion D-tryptophan a tRNA BVI01S_RS12380 purine-nucleoside ribonucleotide- deoxynucleoside dehydrogenase: L-cysteine in tRNA guaB adenylosuccinate phosphorylase: deoxynucleoside long-chain-fatty- D-ribulose 3'-phosphate formamidopyrimidine hydroxy fatty acid BVI01S_RS12385 phosphorylase: nucleoside- diphosphate reductase: kinase: fructose BVI01S_RS15780 synthase: 5-(carboxyamino)imidazole BVI01S_RS06780 kinase: 3-oxoacyl-[acyl- acid--CoA ligase: 5-phosphate BVI01S_RS06780 diphosphate kinase: ndk BVI01S_RS17115 BVI01S_RS21505 BVI01S_RS21505 carrier-protein] bisphosphate [+ 2 isozymes] glutamine- XMP BVI01S_RS13050 ribonucleotide mutase: purE xanthine adenosine BVI01S_RS07045 BVI01S_RS17120 dGMP dAMP aldolase: a 7,8-dihydro- an oxidized all-trans- 966 hydrolyzing dUTP reductase: fabG a single + a ribonucleoside a guanine UDP [+ 5 isozymes] (2E)-hexenoyl-CoA 8-oxoguanine a peptide with a sn-glycerol AHNADPH acetoacetyl-CoA acetamide CAIR BVI01S_RS13780 stranded DNA ammonium ferredoxin [iron- H O heptaprenyl in 16S rRNA a protein carbamoyl- xanthine adenosine dCDP [+ 2 isozymes] 2 penultimate glycine 1-phosphate diphosphate ribonucleotide- glutamine- adenylo-succinate dUTP diphosphatase: in DNA sulfur] cluster diphosphate ribonucleotide- 16S rRNA 3-hydroxybutyryl- amidase domain- phosphate phosphoribosyltransferase: deaminase: stearoyl-CoA fructose- enoyl-CoA diphosphate HslU--HslV hydrolyzing GMP phosphoribosylaminoimidazolesuccinocarboxamide BVI01S_RS16115 nucleoside- a (3R)-3- diphosphate (guanine(966)-N(2) CoA containing protein: synthase: BVI01S_RS03375 BVI01S_RS00455 bisphosphate hydratase: exodeoxyribonuclease NADPH reductase: peptidase synthase: guaA adenylosuccinate nucleoside triphosphate diphosphate kinase: ndk hydroxydodecanoyl-[acp] BVI01S_RS22415 synthase: BVI01S_RS12265 aldolase: DNA- ferredoxin-- heptaprenylglyceryl reductase: )-methyltransferase dehydrogenase: BVI01S_RS17115 ATPase: carB carA lyase: purB BVI01S_RS16190 VII: BVI01S_RS06430 carboxypeptidase: dehydrogenase pyrophosphohydrolase: BVI01S_RS17115 2 RsmD: rsmD BVI01S_RS15770 amidase domain- dCTP 3-hydroxyacyl- BVI01S_RS15835 formamidopyrimidine xseB nitrite reductase: phosphate synthase: NamA: namA an N - (S)-3- BVI01S_RS17120 hslU hslV GMP SAICAR XMP inosine mazG enoyl-CoA BVI01S_RS11740 dGDP dADP ACP dehydratase glycosylase: mutM BVI01S_RS03350 BVI01S_RS12330 BVI01S_RS17120 966 containing protein: carbamoyl hydratase: a 2'- methylguanine hydroxybutanoyl- dUDP a peptide asp AMP dUMP FabZ: fabZ deoxyribonucleoside in 16S rRNA CoA BVI01S_RS16510 phosphate adenylosuccinate purine-nucleoside triose-phosphate BVI01S_RS20125 a single-stranded guanylate nucleoside- nucleoside- fatty acid elongation -- saturated a [DNA]- a 5'-phospho- 7,8-dihydro- a ribonucleoside 3-heptaprenyl- A(H2) NADP + 5'-diphosphate acetate lyase: purB phosphorylase: deoD : isomerase: (S)-3- a peptide with a kinase: gmk diphosphate diphosphate a (2E)-dodec-2-enoyl-[acp] nucleotide- 4-oxo-2-pentenal 5'-monophosphate oligodeoxyribonucleotide nitrite an amino acid sn-glycero- aspartate purine-nucleoside BVI01S_RS21075 BVI01S_RS07435 [DNA] 8-oxoguanine C-terminal glycine : kinase: ndk kinase: ndk D-glyceraldehyde hydroxyhexanoyl-CoA 3'-phosphate 1-phosphate AICAR phosphorylase: DHAP carbamoyltransferase BVI01S_RS18870 dTMP enoyl-ACP an acetoacetyl-[acp] 3-phosphate 3-hydroxyhexanoyl- catalytic subunit: GDP BVI01S_RS06780 reductase bifunctional dTMP kinase: dGTP dATP type I CoA BVI01S_RS07765 ADP FabI: fabI UDP-N-acetyl- decaprenyl-diphospho-N- an apo-[LYS2 L- a ribonucleoside 46 a [protein]- phosphoribosylaminoimidazolecarboxamide glyceraldehyde- dehydrogenase: a guanine 3'-cmp ω hypoxanthine BVI01S_RS13650 α-D-glucosamine acetylmuramoyl-pentapeptide coenzyme A 2-aminoadipyl- Se-methyl-Se-L-methionine a tRNA precursor met fumarate asp 2',3'-cyclic N -phospho- 15-cis-phytoene formyltransferase/IMP cyclohydrolase: purH 3-phosphate BVI01S_RS15770 in tRNA a protein ribonucleotide- dTDP guanine and a dodecanoyl-[acp] carrier-protein] phosphate tRNA bifunctional 2',3'- L-arginine phytoene N-carbamoyl- nucleoside- ribonucleotide- diphosphate dehydrogenase: bifunctional 2',3'- low molecular FAICAR superpathway of pyrimidine deoxyribonucleoside salvage xanthine guanosine salvage 3-oxohexanoyl-CoA undecaprenyldiphospho- (guanosine(46)-N7) cyclic-nucleotide 2'- desaturase: endopeptidase L-aspartate diphosphate diphosphate reductase: nucleoside- gap cyclic-nucleotide 2'- weight protein phosphoribosyltransferase: a 3-oxoacyl-[acp] muramoylpentapeptide beta-N- methionine L-aspartate -methyltransferase phosphodiesterase/ crtI La: lon kinase: ndk reductase: BVI01S_RS17115 diphosphate kinase: ndk holo-ACP synthase: methionine gamma- ribonuclease Z: phosphodiesterase/ arginine bifunctional 2'-deoxycytidine BVI01S_RS03375 beta-ketoacyl- acetyl-CoA C- acetylglucosaminyltransferase: oxidase: 7 TrmB: trmB 3'-nucleotidase: [+ 4 isozymes] : BVI01S_RS17115 13-DPG BVI01S_RS17200 gamma- 3'-nucleotidase: an N - phosphatase: BVI01S_RS17120 phosphoribosylaminoimidazolecarboxamide dTTP guanosine ACP synthase acetyltransferase: lyase: megL BVI01S_RS06625 nadB BVI01S_RS01500 9,15,9'-tri-cis BVI01S_RS07760 adenine and BVI01S_RS15025 lyase: megL 46 BVI01S_RS17120 BVI01S_RS01500 methylguanine BVI01S_RS01175 -ζ-carotene a peptide formyltransferase/IMP cyclohydrolase: purH : 2'-deoxycytidine IMP adenosine salvage I purine-nucleoside II: fabF BVI01S_RS06715 a ribonucleoside cytidine a [protein]- GTP phosphorylase: deoD laurate phosphoglycerate a holo-[LYS2 L- in tRNA (S)-dihydroorotate dADP BVI01S_RS04145 kinase: 3-ketoacyl-ACP [+ 3 isozymes] 3'-phosphate L-arginine 5-aminoimidazole ribonucleotide biosynthesis I kinase: decaprenyl-pyrophosphoryl- UDP 3',5'-ADP 2-aminoadipyl- a single-stranded 2-iminosuccinate succinate IMP [+ 4 isozymes] BVI01S_RS21510 purine-nucleoside long-chain-fatty- 2-oxobutanoate dimethyl selenide mature tRNA 2-oxobutanoate methanethiol adenosine a 3-oxotetradecanoyl-[acp] beta- reductase: BVI01S_RS07440 butanoyl-CoA (N-acetylglucosamine)-N- carrier-protein] oligoribonucleotide dihydroorotate dGDP phosphorylase: nucleoside- acid--CoA ligase: ketoacyl- BVI01S_RS14855 3-phospho- acetylmuramyl-(pentapeptide) dCMP purine-nucleoside BVI01S_RS06780 dehydrogenase diphosphate 2'-deoxyuridine PRPP 3-oxoacyl-[acyl- BVI01S_RS07045 ACP [+ 2 isozymes] acyl-CoA nucleoside- phosphorylase: deoD guanine D-glycerate electron kinase: ndk (d)CMP kinase: carrier-protein] [+ 5 isozymes] synthase dehydrogenase: diphosphate amidophosphoribosyltransferase: purine-nucleoside 2,3-bisphosphoglycerate- 2,3- an N 10 - a dipetide with an N- adenosine guanine 37 an organic transfer subunit: kinase: BVI01S_RS08530 a (3R)-3- BVI01S_RS15780 an L-methionyl- an apo-[aryl- maltohexaose 2-hydroxyisobutyramide 3'-UMP acetyl-CoA an unfolded reductase: fabG a 2,3,4-saturatedII: fabF coenzyme A oxythiamine 2',3'-cyclic Phe kinase: ndk BVI01S_RS12285 phosphorylase: xanthine independent diphosphoglycerate- Met formyltetrahydrofolate terminal L-aspartate in tRNA hydroperoxide BVI01S_RS07745 dATP BVI01S_RS21710 lauroyl-CoA hydroxyacyl-[acyl- [+ 2 isozymes] [initiator tRNA ] carrier protein] protein dCDP BVI01S_RS06780 phosphoribosyltransferase: [+ 2 isozymes] fatty acyl-[acp] phosphoglycerate dependent amidase domain- monophosphate tRNA bifunctional 2',3'- acetyl-CoA thiol superpathway of pyrimidine [+ 2 isozymes] thymidine 5-phospho-β- 3-hydroxyacyl-carrier protein] bifunctional 2',3'- dihydroorotate adenine salvage gly adenine containing protein: (guanosine(37)-N1) cyclic-nucleotide 2'- carboxylase peroxidase: dGTP nucleobases salvage BVI01S_RS03375 a (3R)-3- ACP mutase: phosphoglycerate crotonyl-CoA alpha-glucosidase: cyclic-nucleotide 2'- chaperonin dehydrogenase: nucleoside- D-ribosylamine thiaminase peptidase E: BVI01S_RS22415 -methyltransferase phosphodiesterase/ carboxyl: accA tpx dUMP diphosphate hydroxytetradecanoyl-[acp] dehydratase BVI01S_RS07430 mutase: gpmA methionyl-tRNA holo-ACP synthase: BVI01S_RS17785 phosphodiesterase/ GroEL: groL BVI01S_RS07740 uracil : phosphatidylglycerol II: tenA BVI01S_RS09060 TrmD: trmD 3'-nucleotidase: BVI01S_RS04070 adenine GMP enoyl-CoA formyltransferase: BVI01S_RS17200 amidase domain- 3'-nucleotidase: an N 1 - [+ 2 isozymes] PRPP bifunctional pyr operon kinase: ndk phosphoribosylamine- 3-hydroxyacyl- biosynthesis II (non-plastidic) FabZ: fabZ 2-phospho- alpha-glucosidase: BVI01S_RS01500 thymidylate BVI01S_RS21710 adenine phosphoribosyltransferase: hydratase: BVI01S_RS07680 containing protein: 37 an alcohol orotate -glycine ligase: purD D-glycerate BVI01S_RS16290 BVI01S_RS01500 methylguanine [+ 3 isozymes] a protein transcriptional regulator/uracil [+ 2 isozymes] dCTP ACP dehydratase uridine synthase: BVI01S_RS19345 BVI01S_RS16190 BVI01S_RS16510 in tRNA Phe malonyl-CoA guanine and phosphoribosyltransferase FabZ: fabZ DHAP 5-(hydroxymethyl) 5-(2-hydroxyethyl) 3'-AMP orotate BVI01S_RS21075 phosphopyruvate pyruvate fermentation enoyl-CoA a holo-[aryl- a proteinogenic 2-hydroxy-2- guanosine salvage II PyrR: pyrR NAD(P)H- an N-formyl- 3',5'-ADP -2-methyl-4(1H) -4-methylthiazole asp phosphoribosyltransferase: GAR AMP hydratase: eno a tetrahydrofolate carrier protein] D-glucopyranose maltopentaose amino acid methylpropanoate : adenine a (2E)-tetradec-2-enoyl-[acp] dependent glycerol- to butanoate hydratase: L-methionyl- -pyrimidinone BVI01S_RS07730 uracil acyl-CoA/acyl-ACP met BVI01S_RS12315 phosphoribosyltransferase: 3-phosphate a trans-2- phosphoenol BVI01S_RS20125 [initiator tRNA ] phosphoribosyltransferase: upp phosphoribosylglycinamide pyrimidine ribonucleosides salvage I a 2,3,4-saturated dehydrogenase: guanosine CMP adenine deaminase: ade BVI01S_RS19345 enoyl-ACP dehydrogenase: enoyl-[acyl- pyruvate pyruvate (S)-3- Nucleoside and Nucleotide Degradation UMP formyltransferase: purN fatty acyl-[acp] BVI01S_RS09645 orotidine 5'- phosphorylation reductase BVI01S_RS08490 carrier protein] hydroxybutanoyl-CoA cytidine pyruvate a [glycine-cleavage a single- guanosine a guanine 37 a supercoiled a SpoIVB phosphate UMP kinase: dTMP FabI: fabI sn-glycerol [+ 2 isozymes] coenzyme A AsbD acyl- maltoheptaose a [protein] (L-serine/L- 4-guanidinobutyramide D-glucopyranose CMP FGAR kinase: pyk (S)-3- purine nucleotides degradation II (aerobic) a sulfurated [sulfur carrier] SAM complex H protein] stranded RNA 2',3'-cyclic in tRNA duplex DNA peptidase BVI01S_RS09285 hypoxanthine AMP 3-phosphate acetyl-CoA superpathway of purine deoxyribonucleosides degradation 6 carrier protein threonine) phosphate GTP dTMP kinase: (d)CMP kinase: cytidine deaminase: : hydroxybutanoyl- N -octanoyl-L-lysine amidase domain- monophosphate tRNA glucose 1- DNA Precursor orotidine 5'- guanine a myristoyl-[acp] protein phosphatase bifunctional 2',3'- UDP phosphoribosylformylglycinamidine glycerol-3- enoyl-ACP pyruvate CoA containing protein: (guanosine(37)-N1) dehydrogenase: : helicase SpoIVB phosphate BVI01S_RS13650 BVI01S_RS08530 BVI01S_RS04145 BVI01S_RS09985 acetyl-CoA C- alpha-glucosidase: 2C domain- cyclic-nucleotide 2'- CDP xanthine synthase: purS purQ purL phosphate 1-O- reductase dehydrogeanse: BVI01S_RS22415 BVI01S_RS18160 PcrA: pcrA peptidase: decarboxylase: xanthine nucleoside- [+ 4 isozymes] uridine kinase: udk beta-ketoacyl- AMP polyribonucleotide containing protein: phosphodiesterase/ -methyltransferase BVI01S_RS11155 dTDP phosphoribosyltransferase: FabI: fabI L-lactate acyltransferase: 2'-deoxyguanosine lipoyl holo-ACP synthase: BVI01S_RS17785 spoIVB acyltransferase BVI01S_RS15770 nucleotidyltransferase: pnp amidase domain- 1 TrmD: trmD [+ 4 isozymes] [+ 5 isozymes] BVI01S_RS00405 phosphoribosyltransferase: diphosphate kinase: ndk nucleoside- ACP synthase dehydrogenase: BVI01S_RS09795 BVI01S_RS17200 alpha-glucosidase: BVI01S_RS02225 3'-nucleotidase: an N - diguanylate cyclase: nucleoside- BVI01S_RS03375 FGAM PlsY: plsY synthase: lipA D-glucono- a single a SpoIVB diphosphate uridine CMP bifunctional 2'-deoxyadenosine containing protein: 37 BVI01S_RS17055 orotidine-5'- BVI01S_RS03375 UTP II: fabF a 1-acyl-sn BVI01S_RS16595 [+ 3 isozymes] acetoacetyl-CoA BVI01S_RS16290 stage II sporulation BVI01S_RS01500 methylguanine stranded DNA diphosphate kinase: ndk BVI01S_RS16510 1,5-lactone c-di-GMP peptidase phosphate phosphoribosylformylglycinamidine uridine kinase: metallophosphatase/ a single- protein E: spoIIE 3'-GMP in tRNA CTP synthase: kinase: ndk IMP -glycerol 3- acetoacetyl-CoA a [glycine-cleavage a holo-[AsbD acyl- a nucleoside GMP BVI01S_RS09985 a 3-oxohexadecanoyl-[acp] (S)-lactate acetyl-CoA C- 5'-nucleotidase: IMP purine-nucleoside 3',5'-ADP 4-guanidinobutanoate decarboxylase: CTP cyclo-ligase: BVI01S_RS12290 phosphate 5'-deoxyadenosine 6 an unsulfurated diphosphate stranded RNA a [protein] Ser/Thr BVI01S_RS15805 dTTP acyltransferase: BVI01S_RS20420 phosphorylase: met complex H protein] N carrier protein] D-glucopyranose maltohexaose pyrF uridine kinase: udk 1-acyl-sn-glycerol- (S)-3- adenosine [sulfur carrier] CTP 3-oxoacyl-[acyl- BVI01S_RS09795 GMP deoD -[(R)-lipoyl]-L-lysine AIR 3-phosphate hydroxybutanoyl- bifunctional IMP deaminase: UMP UMP carrier-protein] acyltransferase: CoA [+ 3 isozymes] metallophosphatase/ dehydrogenase: BVI01S_RS00455 purine-nucleoside reductase: fabG bifunctional BVI01S_RS08525 dehydrogeanse: 5'-nucleotidase: guaB purine-nucleoside phosphorylase: a [pyruvate dehydrogenase E2 RNase R degradation N-acetyl-9-O- 3-amino-4- a [protein]-α- propane-1,2,3- [+ 2 isozymes] acetyl-CoA coenzyme A [EntB aryl- maltopentaose a ribonucleoside D-glucopyranose a 1,2-diacyl- BVI01S_RS05000 metallophosphatase/ phosphorylase: BVI01S_RS06780 SAM 6 Ap4A biotin-carboxyl carrier protein assembly BVI01S_RS15770 a sulfurated [sulfur carrier] protein] N -octanoyl-L-lysine substrate RNA acetylneuraminate hydroxybenzaldehyde 3'-phosphate L-glutamate a protein tricarboxylate sn-glycerol 5'-nucleotidase: carrier protein] glucose 1- Carbohydrate Biosynthesis a (3R)-3- (S)-3- XMP 2'-deoxyinosine deoD arylamine N- bifunctional 2',3'- protein-glutamate O- ATP-dependent zinc FAD-dependent bis(5'-nucleosyl)- BVI01S_RS20420 hydroxyhexadecanoyl-[acp] 3-phosphate a [biotin carboxyl- hydroxybutanoyl- adenosine purine-nucleoside acetyltransferase: cyclic-nucleotide 2'- methyltransferase dehydrogenase: tricarballylate tetraphosphatase Secondary Metabolite Biosynthesis alpha-glucosidase: sialate O- metalloprotease phosphatidate carrier protein]-L-lysine ribonuclease BVI01S_RS05110 CheR: BVI01S_RS03275 dehydrogenase gluconeogenesis I 3-hydroxyacyl- CoA bifunctional bifunctional purine-nucleoside phosphorylase: holo-ACP synthase: BVI01S_RS17785 acetylesterase: phosphodiesterase/ FtsH: (symmetrical) cytidylyltransferase: thymine degradation R: rnr BVI01S_RS08435 [+ 4 isozymes] TcuA: tcuA glycogen biosynthesis I (from ADP-D-Glucose) peptidoglycan biosynthesis I (meso-diaminopimelate containing) Cell Structure Biosynthesis ACP dehydratase biotin--[acetyl-CoA- enoyl-CoA adenosine metallophosphatase/ metallophosphatase/ phosphorylase: BVI01S_RS06780 lipoyl synthase: lipA BVI01S_RS17200 arylamine N- 3'-nucleotidase: a [protein]-L- BVI01S_RS13435 YqeK: yqeK BVI01S_RS03170 alpha-glucosidase: BVI01S_RS04860 D-glucono- methylerythritol phosphate pathway I methylerythritol phosphate pathway II deaminase: 5 autoinducer AI-2 biosynthesis I FabZ: fabZ carboxylase] ligase: hydratase: 5'-nucleotidase: 5'-nucleotidase: deoD BVI01S_RS16290 acetyltransferase: BVI01S_RS01500 glutamate-O a peptide cis-aconitate ADP (S)-malate D-glucopyranose thymine 1,5-lactone UDP-N-acetyl-α-D-glucosamine phosphatidate BVI01S_RS08315 BVI01S_RS16190 BVI01S_RS00455 BVI01S_RS05000 BVI01S_RS20420 purine-nucleoside BVI01S_RS12450 a ribonucleoside -methyl-ester 6-phosphate D-glyceraldehyde D-glyceraldehyde dihydrothymine a nucleoside 5'- 3-acetylamino-4- pyruvate pyruvate a (2E)-hexadec-2-enoyl-[acp] cytidylyltransferase: a [biotin carboxyl-carrier enoyl-CoA bifunctional phosphorylase: a [pyruvate dehydrogenase 3',5'-ADP a holo-[EntB aryl- a diribonucleotide acetate N-acetylneuraminate 3-phosphate 3-phosphate UDP-N-acetylglucosamine BVI01S_RS09300 dehydrogenase: 5'-deoxyadenosine carrier protein] monophosphate hydroxybenzaldehyde phospho- SAM protein]-N 6 -biotinyl-L-lysine hydratase: inosine guanosine metallophosphatase/ BVI01S_RS06780 met E2 protein] N 6 -lipoyl-L-lysine an unsulfurated [sulfur carrier] D-glucopyranose maltotetraose 1-carboxyvinyltransferase: preA sugar mutase: enoyl-ACP a CDP- BVI01S_RS20125 5'-nucleotidase: 2-deoxy-α-D- 1-deoxy-D-xylulose- 1-deoxy-D-xylulose- BVI01S_RS15845 5,6-dihydrothymine malate BVI01S_RS16305 reductase diacylglycerol purine-nucleoside purine-nucleoside BVI01S_RS05000 ribose 1-phosphate α 5-phosphate 5-phosphate dehydrogenase: -D- UDP-N-acetylglucosamine FabI: fabI CDP-diacylglycerol-- crotonyl-CoA phosphorylase: phosphorylase: dihydropyrimidinase: malate SAH a [biotin carboxyl- phosphopentomutase: UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N N-acetyl-4-O- (-)-methyl a [release factor]- adenine 37 a negatively an organic BVI01S_RS04080 glucopyranose synthase: synthase: 1-carboxyvinyltransferase: deoD deoD hydA coenzyme A [EntF L-seryl- NADP + coenzyme A maltotriose a dipeptide histidinol glycerol-3-phosphate 3- xanthosine γ val dehydrogenase, BVI01S_RS06450 BVI01S_RS06450 murA a palmitoyl-[acp] carrier-protein dimer]- butanoyl-CoA deoB -acetylmuramoyl-L-alanyl- - acetylneuraminate jasmonate L-glutamine in tRNA supercoiled DNA hydroperoxide malate 1-phosphate phosphatidyltransferase: purine-nucleoside purine-nucleoside carrier protein] 1 DNA NAD-requiring: 5'-methylthioadenosine/ N 6 -biotinyl-L-lysine dehydrogenase 3-(carbamoylamino)- D-glutamyl-L-lysyl- D-alanine peptide chain tRNA1(Val) membrane alkyl histidinol glucose-1-phosphate UDP-N-acetyl-α-D- 2-deoxy-D-ribose dehydrogenase: pgsA + phosphorylase: phosphorylase: 2-methylpropanoate release factor (adenine(37)-N6)- topoisomerase III: hydroperoxide BVI01S_RS04080 1-deoxy-D-xylulose 1-deoxy-D-xylulose S-adenosylhomocysteine acetyl-CoA (NAD , ferredoxin) undecaprenyldiphospho- CoA-disulfide alpha-glucosidase: dipeptidase: dehydrogenase: mdh adenylyltransferase: glucosamine-enolpyruvate 1-(3-sn- BVI01S_RS06780 BVI01S_RS06780 5-phosphate sialate O- BVI01S_RS14540 5-phosphate 5-phosphate nucleosidase: : BVI01S_RS15780 purine-nucleoside β-ureidopropionase: muramoylpentapeptide beta-N- holo-ACP synthase: carboxylesterase: N(5)-glutamine methyltransferase: BVI01S_RS01765 reductase hisD BVI01S_RS21435 carboxylase biotin reductase: BVI01S_RS17785 acetylesterase: BVI01S_RS10355 UDP-N-acetylmuramate phosphatidyl) acetyl-CoA BVI01S_RS07415 methyltransferase: 6 BVI01S_RS13620 [+ 3 isozymes] subunit F: ahpF 1-deoxy-D-xylulose- carboxylase subunit: phosphorylase: BVI01S_RS14525 acetylglucosaminyltransferase: BVI01S_RS17200 BVI01S_RS18165 alpha-glucosidase: BVI01S_RS04860 an N - a proteinogenic glucose-1-phosphate 1-deoxy-D-xylulose- dehydrogenase: murB -sn-glycerol butanoyl-CoA hypoxanthine guanine deoxyribose- prmC his 5'-methylthioadenosine/ carboxylase deoD BVI01S_RS15025 methyladenine 37 a relaxed DNA an alcohol 5-phosphate 5-phosphate ala palmitate BVI01S_RS07955 phosphate BVI01S_RS16290 a [release factor]-N 5 amino acid adenylyltransferase: glu α 3-phosphate carboxyltransferase (R)-3-amino-2- val reductoisomerase: reductoisomerase: S-adenosylhomocysteine UDP-N-acetyl- -D-muramate purine-nucleoside aldolase: deoC a holo-[EntF in tRNA BVI01S_RS21430 phosphatidylglycerophosphatase acetyl-CoA phosphate methylpropanoate -methyl-L-glutamine 1 nucleosidase: mtnN long-chain-fatty- subunit beta: ditrans,octacis-undecaprenyldiphospho- UDP + N-acetylneuraminate (-)-jasmonate MeOH oxaloacetate BVI01S_RS09305 BVI01S_RS09305 A: BVI01S_RS15635 carboxylase butyryltransferase: phosphorylase: 3',5'-ADP L-seryl-carrier CoA-disulfide NADPH H acetate a (1->4)- BVI01S_RS04070 N-acetyl-(N-acetylglucosaminyl)muramoyl- D-glucopyranose maltose pyruvate ADP-α-D-glucose glutamate UDP-N-acetylmuramate- acid--CoA ligase: biotin carboxylase BVI01S_RS06780 protein] α-D-glucan S-ribosyl-L-homocysteine phosphatidylglycerophosphatase yqiS acetaldehyde D-glyceraldehyde 3-phosphate L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine MEP MEP racemase: racE -L-alanine ligase: BVI01S_RS07045 subunit: accC phosphoenolpyruvate glycogen BVI01S_RS20980 A: BVI01S_RS13700 butanoyl UDP-α-D-glucose [+ 5 isozymes] an L-1- a [carboxyl-carrier carboxykinase phosphoenolpyruvate synthase phosphate xanthine β 2-C-methyl-D- 2-C-methyl-D- S-ribosylhomocysteine D-glt phosphatidyl- 6 UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N-acetylmuramoyl-L- D-xylulose D-erythrose a 1-(1-alkenyl) an N-acetyl- - an [RNA]-3'- a [protein]-L- (ATP): pckA synthase: ppsA GlgA: glgA biosynthesis palmitoyl-CoA protein dimer]-N - pseudouridine coenzyme A canavaninosuccinate a [protein]- pentanoate a nucleoside erythritol 4-phosphate erythritol 4-phosphate lyase: BVI01S_RS14830 UDP-N-acetyl-α-D-muramoyl-L-alanine superpathway of pyrimidine alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine VibB -sn-glycero-3- D-hexosaminide ribonucleoside- pyruvate ω a (1->4)- sn-glycerol carboxybiotinyl-L-lysine butyrate kinase: degradation 5-phosphate 4-phosphate proline ( = 180) L-arginine triphosphate D-glucopyranose cytidylyltransferase: cytidylyltransferase: deoxyribonucleosides degradation phosphocholine 2',3'- pyruvate oxidase: peptidylprolyl phosphoenol α-D-glucan BVI01S_RS06505 acetyl-CoA superpathway of pyrimidine undecaprenyldiphospho- protein nucleoside 6-phosphate BVI01S_RS17345 BVI01S_RS17345 AI-2 UDP-N-acetylmuramoyl- cyclophosphate BVI01S_RS04305 isomerase: butyrate kinase: pyruvate phospho- pseudouridine 2'-deoxycytidine ribonucleosides degradation muramoylpentapeptide beta-N- beta-N- RNA 2',3'-cyclic : triphosphatase 4-(cytidine 5'- 4-(cytidine 5'- L-alanine--D- butanoate transketolase: argininosuccinate pyruvate oxidase: BVI01S_RS13890 BVI01S_RS06505 sugar mutase: pseudouridine urate holo-ACP synthase: acetylhexosaminidase: phosphodiesterase: BVI01S_RS17320 diphospho)-2-C- acetylglucosaminyltransferase: BVI01S_RS01620 lysoplasmalogenase: YtkD: ytkD phosphopyruvate BVI01S_RS16305 diphospho)-2-C- glutamate ligase: kinase: cytidine BVI01S_RS17200 nagZ lyase: argH BVI01S_RS02975 [+ 5 isozymes] a [protein]- UDP-N-acetyl-D- α-D-glucopyranose cytidine deaminase: BVI01S_RS15025 BVI01S_RS00835 thpR ω pentanoyl hydratase: eno methyl-D-erythritol methyl-D-erythritol BVI01S_RS07885 BVI01S_RS03090 cytidine deaminase: [+ 2 isozymes] an [RNA]-3'- a [protein]-L- N -phospho- a nucleoside glucosamine biosynthesis I a glycogen 1-phosphate BVI01S_RS04145 acetyl phosphate ω phosphate 4-(cytidine 5'- 4-(cytidine 5'- (2R,4S)-2-methyl-2,4- pseudouridine BVI01S_RS04145 ribunucleoside- proline ( = 0) L-arginine diphosphate 2-phospho- α [+ 4 isozymes] thymidine 5'-deoxyadenosine degradation II an N-acetyl-β- D-glucopyranose UTP--glucose- diphospho)- diphospho)- dihydroxydihydrofuran-3-one meso-diaminopimelate UDP-N-acetyl- -D-muramoyl- 5'-phosphate [+ 4 isozymes] ditrans,octacis-undecaprenyldiphospho-N- D-glyceraldehyde 2'-phosphate D-glycerate UDP 3',5'-ADP a holo-[VibB aryl- F6P sn-glycero-3- an alcohol D-hexosamine L-canavanine fumarate 6-phosphate 1-phosphate 2-C-methyl-D- 2-C-methyl-D- L-alanyl-D-glutamate (S)-lactate fermentation to propanoate, acetate and hydrogen uridine acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L- 3-phosphate a fatty aldehyde glucose-6- pseudouridine- 2'-deoxyuridine pyrimidine- carrier protein] phosphocholine 2,3-bisphosphoglycerate- uridylyltransferase : erythritol kinase: 5'-deoxyadenosine alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine independent phosphate UDP-N-acetylmuramoyl- 5'-phosphate nucleoside pyrimidine-nucleoside GalU: galU BVI01S_RS13565 BVI01S_RS13565 (S)-lactate phosphoglycerate isomerase: L-alanyl-D-glutamate-- glycosidase: phosphorylase: phosphorylase: 2-phospho-4-(cytidine 2-phospho-4-(cytidine (2R,4S)-2-methyl-2,3,3,4- 5'-methylthioadenosine/ β α (5R)-5,6-dihydro- BVI01S_RS20205 UTP--glucose- BVI01S_RS03085 BVI01S_RS06785 BVI01S_RS06785 a 2-deoxy-D- a [DNA]-3'- methyl (indol- a -Gal-(1->3)- -Gal-(1->2) (R)-3- mutase: 5'-diphospho)-2-C- 5'-diphospho)-2-C- tetrahydroxytetrahydrofuran 2, 6-diaminopimelate L-lactate dehydrogenase: S-adenosylhomocysteine dethiobiotin a sulfurated a nucleobase F6P 3'-ketolactose wound RNA oxaloacetate a DNA segment F6P 1-phosphate SAM ribosyl-base -[α-(1->6)-oligomannan] 5-(thymidin-7-yl) BVI01S_RS07430 methyl-D-erythritol methyl-D-erythritol ligase: BVI01S_RS17060 pyrimidine- nucleosidase: uracil [sulfur carrier] hydroxyl 3-yl)acetate hydroxybutanoate uridylyltransferase BVI01S_RS16595 uracil thymine polysaccharide 3-hydroxybutyrate / thymidine (in DNA) 3-phospho- 2-C-methyl-D- 2-C-methyl-D- nucleoside BVI01S_RS10355 glutamine-- GalU: galU UDP-N-acetylmuramoyl- D-ala dihydropyrimidine pyruvyl dehydrogenase: RNA helicase: methylcitrate spore D-glycerate erythritol 2,4- erythritol 2,4- peptidoglycan maturation (meso-diaminopimelate containing) pyruvate phosphorylase: nucleoside 2- fructose-6- fructose-6- L-alanyl-D-glutamate-- 5'-methylthioadenosine/ dehydrogenase: preA biotin exodeoxyribonuclease carboxylesterase: beta-glucosidase: transferase BVI01S_RS14685 BVI01S_RS03115 synthase: photoproduct RecA: recA UDP-α-D-glucose cyclodiphosphate cyclodiphosphate BVI01S_RS06785 deoxyribosyltransferase: phosphate phosphoglycerate phosphate 2, 6-diaminopimelate D-alanine--D-alanine lipid II (meso S-adenosylhomocysteine synthase III: xth BVI01S_RS07415 BVI01S_RS12040 CsaB: csaB [+ 2 isozymes] BVI01S_RS19760 lyase: splB a DNA segment synthase: synthase: BVI01S_RS16690 aldolase: fsa a 4,6-CH (COO-)C-β- kinase: ligase: BVI01S_RS07900 nucleosidase: mtnN 5,6-dihydrouracil 3 (2S,3S)-2- two adjacent transaminase preQ biosynthesis ligase: BVI01S_RS17240 diaminopimelate containing) pyruvate carboxylase: pyc BioB: bioB acetoacetate an unwound RNA in reverse BVI01S_RS17350 BVI01S_RS17350 0 Gal-(1->3)-α-Gal-(1->2) in DNA BVI01S_RS07440 (isomerizing) β methylcitrate orientation dTDP- -L-rhamnose α peptidoglycan 5-deoxy-D-ribose a 2'- 3-keto-β-D- α 2-C-methyl-D-erythritol- 2-C-methyl-D-erythritol- UDP-N-acetyl- -D-muramoyl-L-alanyl- D-alanyl-D-alanine dihydropyrimidinase: a [DNA]-3'- D-glucopyranose -[ -(1->6)-oligomannan] : glmS biosynthesis glycosyltransferase: uracil 2-deoxy-α-D- an unsulfurated a 2-deoxy-D- dihydroxyacetone D-glyceraldehyde (indol-3-yl)acetate MeOH galactose 13-DPG γ-D-glutamyl-meso-2,6-diaminopimelate hydA biotin 5'-deoxyadenosine a nucleobase hydroxyl deoxyribonucleoside D-glucosamine 2,4-cyclodiphosphate 2,4-cyclodiphosphate oxaloacetate ribose 1-phosphate S-methyl-5- met ribosyl-base 3-phosphate α-D-glucopyranose GTP spoVE formate acetyl-CoA [sulfur carrier] 5'-monophosphate 6-phosphate thioribose kinase: type I 1-phosphate flavodoxin- flavodoxin- GTP UDP-N-acetylmuramoyl- a nascent peptidoglycan : phosphopentomutase: 3-ureidopropanoate γ BVI01S_RS10455 glyceraldehyde- phosphoglucosamine glucose-1-phosphate dependent dependent cyclohydrolase tripeptide--D-alanyl- with (L-alanyl- -D-glutamyl- BVI01S_RS04080 phosphate deoB 7,8- uridine 2'3'-cyclic (2Z,4E)-2- 3-phosphate mutase: thymidylyltransferase (E)-4-hydroxy- (E)-4-hydroxy- I FolE: folE D- alanine ligase: meso-2,6-diaminopimeloyl-D- malate dehydrogenase: mdh acetyltransferase: pta 5-deoxy-α-D- β-ureidopropionase: 5-amino-4- D-cellobiose all-trans- a 3,5,7,9,11,13,15- dihydroneopterin 2-deoxy-D-ribose UDP-N-acetyl-α-D-muramoyl- D-alanyl-D-alanine PRPP coenzyme A MeOH a double CAIR BVI01S_RS19245 RfbA: rfbA 3-methylbut- 3-methylbut- BVI01S_RS17235 alanyl-D-alanine) pentapeptide BVI01S_RS14525 6'-phosphate hepta-oxo- monophosphate hydroxyhexa- D-serine triose-phosphate dehydrogenase: α ribose 1-phosphate L-alanyl-γ-D-glutamyl-L-lysine imidazolecarboxyamide retinyl palmitate stranded DNA α dTDP- -D-glucose 2-enyl- 2-enyl- 3'-triphosphate (S)-malate H 5-phosphate hexadecanoyl-[PKS-acp] bifunctional 2',3'- catalase/peroxidase 2,4-dienedioate 5-(carboxyamino) isomerase: gap -D-glucosamine 2 acetyl phosphate aldo/keto DNA/RNA α penicillin-binding S-methyl-5- cyclic-nucleotide 2'- HPI: katG 4-oxalocrotonate D-serine BVI01S_RS07435 1-phosphate dTDP-glucose 4,6- diphosphate diphosphate 6-carboxytetrahydropterin UDP-N-acetyl- -D-muramoyl-L- β-alanine reductase: nuclease imidazole D-glyceraldehyde γ fumarate hydratase: deoxyribose- thioribose-1- UDP-N-acetylmuramoyl- adenine 6-phospho-beta- phosphodiesterase/ tautomerase: ammonia-lyase: DHAP dehydratase: rfbB synthase: ispG synthase: ispG synthase QueD: queD alanyl- -D-glutamyl-meso-2,6- di-trans,octa-cis-undecaprenyl phosphate protein 2: acetate kinase: CoA pyrophosphatase: carboxylesterase: BVI01S_RS06735 catalase: SfsA: sfsA ribonucleotide 3-phosphate bifunctional UDP-N- BVI01S_RS02910 phosphate phosphate tripeptide--D-alanyl- phosphoribosyltransferase: glucosidase: 3'-nucleotidase: BVI01S_RS15705 BVI01S_RS20660 dTDP-4-dehydro-6- (E)-4-hydroxy-3- (E)-4-hydroxy-3- 6-carboxy-5,6,7,8- diaminopimeloyl-D-alanyl-D-alanine a nascent peptidoglycan BVI01S_RS03695 a mature peptidoglycan with BVI01S_RS14050 BVI01S_RS21670 BVI01S_RS07415 [+ 3 isozymes] BVI01S_RS15180 mutase: purE acetylglucosamine γ γ aldolase: deoC isomerase: mtnA D- alanine ligase: BVI01S_RS19345 BVI01S_RS05180 9-hydroxy-3,5,7,11,13,15- BVI01S_RS01500 (3E)-2-oxohex- deoxy-α-D-glucopyranose methylbut-2-en- methylbut-2-en- with (L-alanyl- -D-glutamyl- [+ 3 isozymes] (L-alanyl- -D-glutamyl-meso- class II fumarate a 5'-phosphooligonucleotide pyruvate AIR diphosphorylase/ tetrahydropterin hexaoxohexadecanoyl- formaldehyde 3-enedioate 1-yl diphosphate 1-yl diphosphate phospho-N- meso-2,6-diaminopimeloyl- 2,6-diaminopimeloyl-D-alanyl- hydratase: fumC acetate 5-deoxy-D-ribulose BVI01S_RS17235 3'-UMP glucosamine-1- dTDP-4- 4-hydroxy-3- 4-hydroxy-3- 7-carboxy-7- [PKS-acp] acetylmuramoyl- D-alanine) tetrapeptide a nascent peptidoglycan D-alanine) pentapeptide acetaldehyde 1-phosphate D-glucopyranose fructose phosphate N- dehydrorhamnose methylbut-2-enyl methylbut-2-enyl D-glyceraldehyde 3-phosphate UTP and CTP dephosphorylation I AICAR D-glucopyranose 3',5'-ADP 4'-phosphopantetheine all-trans-retinol palmitate deazaguanine pentapeptide- with D,D cross-links (meso- fumarate UDP-N-acetyl-α-D-muramoyl-L-alanyl- 6-phosphate bisphosphate acetyltransferase 3,5-epimerase: rfbC diphosphate diphosphate synthase transferase: L,D-transpeptidase: L,D-transpeptidase: diaminopimelate containing) γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine aldolase: GlmU: glmU dTDP-4-dehydro- UTP reductase: reductase: QueE: queE BVI01S_RS07890 BVI01S_RS06575 BVI01S_RS06575 BVI01S_RS13780 β-L-rhamnose N-acetyl-α-D- 4-hydroxy-3- BVI01S_RS19155 4-hydroxy-3- BVI01S_RS19155 7-carboxy-7- a nascent peptidoglycan with a mature peptidoglycan nucleoside CTP synthase: α an N-terminal L- fructose- glucosamine dTDP-4- IPP IPP a nascent peptidoglycan a nascent peptidoglycan a purine base + -maltose 6'- methylbut-2-enyl methylbut-2-enyl deazaguanine undecaprenyldiphospho- (L-alanyl-γ-D-glutamyl-meso- with (L-alanyl-γ-D-glutamyl- acetyl-CoA acetaldehyde DHAP H hydrogencarbonate a ribonucleoside a single an all-trans-retinyl ester a holo [PedD acyl- ethanol D-glycerate pullulan squalene bisphosphate dehydrorhamnose γ a mature peptidoglycan succinate triphosphatase BVI01S_RS15805 lesion in DNA phosphate alanyl-[S18 protein thr 1-phosphate diphosphate diphosphate N-acetylmuramoyl-L-alanyl- with L,D cross links (meso- with (L-alanyl- -D-glutamyl- triphosphate stranded DNA carrier protein] type I aldolase: 7-cyano-7- 2,6-diaminopimelate) tripeptide meso-2,6-diaminopimeloyl- with D,D cross-links (meso- propanoyl-CoA YtkD: ytkD of 30S ribosome] catalase/peroxidase squalene- bifunctional UDP-N- reductase: rfbD reductase: reductase: γ-D-glutamyl-meso-2,6- diaminopimelate containing) meso-2,6-diaminopimeloyl- ribosomal protein D-glycerate deazaguanine D-alanine) tetrapeptide diaminopimelate containing) CTP ACP S- HPI: katG L-threonine 3- pullulanase: pulA -hopene BVI01S_RS15835 β BVI01S_RS19155 type 2 isopentenyl- BVI01S_RS19155 type 2 isopentenyl- glycine) tetrapeptide S18-alanine N- dehydrogenase: acetylglucosamine dTDP- -L-rhamnose synthase diaminopimeloyl-D-alanyl-D-alanine UDP DNA- carbonic 6-phospho-alpha- carboxylesterase: malonyltransferase: dehydrogenase: cyclase: diphosphate diphosphate nucleoside DNA : acetyltransferase: catalase: BVI01S_RS13710 pullulanase: diphosphorylase/ QueC: queC undecaprenyldiphospho- formamidopyrimidine anhydrase: glucosidase: BVI01S_RS07415 fabD BVI01S_RS16930 shc Delta-isomerase: Delta-isomerase: a mature peptidoglycan with BVI01S_RS19190 an N-terminal N-acetyl-rimI BVI01S_RS15180 BVI01S_RS01990 glucosamine-1- muramoylpentapeptide beta-N- purine ribonucleosides degradation triphosphatase glycosylase: mutM BVI01S_RS12185 BVI01S_RS16640 a malonyl- hydroxypyruvate BVI01S_RS08515 BVI01S_RS08515 a mature peptidoglycan (L-alanyl-γ-D-glutamyl-meso- acetaldehyde aminoacetone maltotriose hop-22(29)-ene β-D-fructose 1,6- phosphate N- preQ YtkD: ytkD L-alanyl-[S18 protein [PedD acyl- 0 acetylglucosaminyltransferase: with L,D cross-links (meso- 2,6-diaminopimelate) tripeptide a mature peptidoglycan bisphosphate acetyltransferase γ (S)-methylmalonyl-CoA succinyl-CoA CDP a [DNA]- of 30S ribosome] carrier protein] BVI01S_RS15025 diaminopimelate containing) with (L-alanyl- -D-glutamyl- UMP a 5'-phospho- a modified D-glucopyranose all-trans-retinol a fatty acid GlmU: glmU adenosine 4-oxo-2-pentenal CO H O D-glucopyranose ssDNA/pppN(pN) class II fructose- DMAPP DMAPP meso-2,6-diaminopimeloyl- nucleotide- [DNA] nucleobase 2 2 6-phosphate lipid II (meso diaminopimelate containing) bifunctional hybrid bisphosphatase: UDP-N-acetyl- glycine) tetrapeptide 3'-phosphate n -1 metallophosphatase/ glpX α-D-glucosamine methylmalonyl- adenosine 5'-nucleotidase: glutaminyl-tRNA gln Aminoacyl-tRNA Charging methylmalonyl-CoA CoA mutase: scpA deaminase: CMP 1518 cytidine 2',3'-cyclic (2Z,4Z)-2-chloro- γ F6P BVI01S_RS20420 an [HPr]- phosphoenol 7,8-dihydrofolate + a 5S rRNA adenine / -glutamyl- hexulose 6- PRPP biosynthesis biosynthesis via transamidation epimerase: mce BVI01S_RS00455 NADPH H HMG-CoA monophosphate a holo [BryU acyl- 5-hydroxyhexa- D-glycerate bifunctional L-histidine pyruvate monoglutamate precursor 1519 isopropylamide lys (R)-methylmalonyl-CoA bifunctional adenine in 16S rRNA bifunctional 2',3'- carrier protein] phosphate glucose-6- metallophosphatase/ 16S rRNA 2,4-dienedioate D-glycerate D-ribose 5- xanthosine adenosine inosine guanosine metallophosphatase/ cyclic-nucleotide 2'- ACP S- 4-oxalocrotonate ferredoxin: 6-phospho-3- lysine 2,3- phosphate glu 5'-nucleotidase: (adenine(1518)-N(6)/ dehydrogenase: phosphate 2-oxoglutarate decarboxylation to succinyl-CoA Respiration 5'-nucleotidase: phosphoenolpyruvate- dihydrofolate hydroxymethylglutaryl- phosphodiesterase/ malonyltransferase: tautomerase: BVI01S_RS20355 hexuloisomerase: aminomutase: isomerase: ribose-phosphate BVI01S_RS20420 ribonuclease adenine(1519)-N(6))- BVI01S_RS13710 BVI01S_RS05000 -protein reductase: CoA lyase: 3'-nucleotidase: fabD BVI01S_RS15705 hxlB ablA BVI01S_RS20205 diphosphokinase: tRNA charging M5: rnmV dimethyltransferase γ gln a [2-oxoglutarate bifunctional : ptsP BVI01S_RS21070 BVI01S_RS06710 a malonyl- (3E)-2-chloro-5- N-( -L-glutamyl) BVI01S_RS13540 purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside uridine RsmA: rsmA BVI01S_RS01500 hydroxypyruvate F6P L-β-lysine D-glucopyranose dehydrogenase metallophosphatase/ N 6 -dimethyladenine 1518 [BryU acyl- oxohex-3-enedioate -L-alaninol PRPP elongator phosphorylase: phosphorylase: phosphorylase: phosphorylase: 3'-cmp 6-phosphate Asp-tRNA(Asn) pro a tRNA Pro ile a tRNA Ile trp a tRNA Trp thr a tRNA Thr tyr a tRNA Tyr his a tRNA His met initiator tRNA Met met arg a tRNA Arg E2 protein] N 6 5'-nucleotidase: /N 6 -dimethyladenine 1519 carrier protein] an L-glutamyl- Met 2-oxoglutarate deoD deoD deoD deoD an [HPr protein]- a double-stranded tRNA 5,6,7,8- + a mature 5S-rRNA /Glu-tRNA(Gln) Gln -lipoyl-L-lysine BVI01S_RS05000 π pyruvate NADP acetoacetate acetyl-CoA in 16S rRNA [tRNA ] dehydrogenase N -phospho- tetrahydrofolate oligonucleotide amidotransferase: purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside cys a tRNA Cys a tRNA Ala ala tRNA asp asp ser a tRNA ser 2-oxoglutarate E1 component: cytidine L-histidine BVI01S_RS12380 Asp-tRNA(Asn) phosphorylase: phosphorylase: phosphorylase: phosphorylase: S-methyl-5'- Asn proline-- Lys isoleucine-- Leu tryptophan- threonine- glu tyrosine-- histidine-- Gly methionine-- methionine-- arginine-- Phe dehydrogenase BVI01S_RS08925 /Glu-tRNA(Gln) asn tRNA lys a tRNA leu a tRNA glu a tRNA gly a tRNA phe a tRNA BVI01S_RS06780 BVI01S_RS06780 BVI01S_RS06780 BVI01S_RS06780 thioadenosine degradation I BVI01S_RS12385 tRNA ligase: Val tRNA ligase: -tRNA -tRNA tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: E1 component: val a tRNA 1402 amidotransferase: Gln D-glyceraldehyde D-sedoheptulose D-threo-7,8- p-nitrophenyl- a cytidine (2R,3S)-3- gatC gatA gatB BVI01S_RS09315 BVI01S_RS14165 ligase: trpS ligase: thrS cysteine- BVI01S_RS17695 alanine- BVI01S_RS19370 aspartate- BVI01S_RS20290 BVI01S_RS20290 BVI01S_RS21180 serine- gln a tRNA BVI01S_RS08925 S-methyl-5'- coenzyme A an apo [peptidyl- protoporphyrinogen IX a holo [BryP acyl- maltose homogentisate nitric oxide gatC gatA gatB α-D-ribose- 3-phosphate 7-phosphate dihydroneopterin β-D-galactoside in 16S rRNA isopropylmalate thr [+ 11 isozymes] asparagine- proline-- lysine- isoleucine- -- tryptophan-- threonine- glutamate-- -tRNA tyrosine-- -tRNA histidine-- -tRNA glycine-- methionine- methionine- arginine-- -tRNA phenylalanine-- [+ 3 isozymes] thioadenosine carrier protein] carrier protein] a 5-phosphooxy- a [2-oxoglutarate a [2-oxoglutarate 1-phosphate 5'-methylthioadenosine/ pyrimidine deoxyribonucleotides protoporphyrinogen 16S rRNA alpha-glucosidase: 3-isopropylmalate homogentisate NO-inducible L-glutamyl- -tRNA tRNA ligase: valine--tRNA ligase: -tRNA -tRNA tRNA ligase: tRNA ligase: -tRNA tRNA ligase: ligase: tRNA ligase: ligase: tRNA ligase: ligase: tRNA ligase: -tRNA -tRNA tRNA ligase: ligase: tRNA ligase: pheS dehydrogenase dehydrogenase S-adenosylhomocysteine dephosphorylation oxidase: (cytidine(1402)-2'-O) ACP S- BVI01S_RS17785 threonine ammonium phosphopentomutase: dehydrogenase: 1,2-dioxygenase: flavohemoprotein: [tRNA Gln ] ligase: asnS BVI01S_RS03005 BVI01S_RS11375 ligase: lysS ligase: ileS BVI01S_RS14680 BVI01S_RS11575 ligase: thrS BVI01S_RS17355 cysS BVI01S_RS11855 alaS BVI01S_RS10035 aspS BVI01S_RS19955 ligase: metG ligase: metG BVI01S_RS15740 serS BVI01S_RS16145 E2 protein] N 6 E2 protein] N 6 -S- nucleosidase: nucleoside triphosphate transketolase: dihydroneopterin beta-glucosidase: BVI01S_RS19825 -methyltransferase: malonyltransferase: alpha-glucosidase: ammonia- deoB holo-ACP synthase: leuB BVI01S_RS09880 hmpA -dihydrolipoyl- succinyldihydrolipoyl- BVI01S_RS10355 pyrophosphohydrolase: BVI01S_RS01620 aldolase: folB BVI01S_RS12040 rsmI fabD BVI01S_RS16290 lyase: ilvA an L-methionyl- BVI01S_RS17200 protoporphyrinogen a 2'-O- a malonyl- 4-methyl-2- 4-maleyl- Asp-tRNA(Asn) an L-asparaginyl- an L-prolyl- an L-valyl- an L-lysyl- an L-isoleucyl- an L-leucyl- an L-tryptophanyl- an L-threonyl- an L-glutamyl- an L-cysteinyl- an L-tyrosyl- an L-alanyl- an L-histidyl- an L-aspartyl- an L-methionyl- an L-arginyl- an L-seryl- an L-phenylalanyl- an L-glutaminyl- L-lysine L-lysine D-ribose 5- mazG [+ 2 isozymes] nitrate 2-oxobutanoate a glycyl-[tRNA Gly ] [elongator 5'-methylthioadenosine/ oxidase: hemY methylcytidine 1402 [BryP acyl- D-glucopyranose oxopentanoate acetoacetate /Glu-tRNA(Gln) [tRNA Asn ] [tRNA Pro ] [tRNA Val ] [tRNA Lys ] [tRNA Ile ] [tRNA Leu ] [tRNA Trp ] [tRNA Thr ] [tRNA Glu ] [tRNA Cys ] [tRNA Tyr ] [tRNA Ala ] [tRNA His ] [tRNA asp ] [initiator tRNA Met ] [tRNA Arg ] [tRNA ser ] [tRNA Phe ] [tRNA Gln ] phosphate dCTP dCMP tRNA Met ] S-adenosylhomocysteine protoporphyrin IX in 16S rRNA carrier protein] amidotransferase: D-ribose 5- D-xylulose 6-(hydroxymethyl) glycolaldehyde D-galactopyranose 4-nitrophenol nucleosidase: mtnN 3',5'-ADP a holo [peptidyl- gatC gatA gatB 2-oxoglutarate MTR dUTP diphosphatase: carrier protein] phosphate 5-phosphate -7,8-dihydropterin dehydrogenase BVI01S_RS16115 an L-glutaminyl- E1 component: S-methyl-5- nucleoside triphosphate Gln thioribose kinase: N,N',N''- 1915 527 [tRNA ] BVI01S_RS08925 pyrophosphohydrolase: a pyrimidine base a 1-O-(alk-1-enyl)-sn-glycero- a pseudouridine a holo [PedN acyl- a guanine (2E,4Z)-deca- a (2E,4E)-2,4- BVI01S_RS10455 triacetylchitotriose hydantoin 2-chloroacetate D-glycerate gly 2-oxoglutarate mazG lesion in DNA 3-phosphoethanolamine in 23S rRNA carrier protein] in 16S rRNA 2,4-dienoyl-CoA dienoyl-CoA dUTP dUMP 23S rRNA 16S rRNA haloacid 2,4-dienoyl- 2,4-dienoyl- dehydrogenase 5-MTR-1-P dihydropyrimidinase: ACP S- : glycine beta-N- (pseudouridine(1915)- (guanine(527)-N(7) dehalogenase type CoA reductase: CoA reductase: complex hydA malonyltransferase: BVI01S_RS16825 oxidase endonuclease lysoplasmalogenase: acetylhexosaminidase: N(3))-methyltransferase )-methyltransferase II: BVI01S_RS16860 BVI01S_RS10630 BVI01S_RS10630 dihydrolipoyllysine- 5-hydroxy-CTP 5-hydroxy-CMP fabD ThiO: thiO VIII: nei BVI01S_RS00835 nagZ 3 RlmH: rlmH 7 RsmG: rsmG residue an N - a malonyl[PedN an N - glycolate (2E)-dec-2- a (2E)-2- 2-phospho- 1915 N-carbamoylglycine 527 glyoxylate succinyltransferase: methylpseudouridine acyl-carrier methylguanine enoyl-CoA enoyl-CoA D-glycerate selenate reduction Inorganic Nutrient Metabolism a [DNA]- N,N'- N-acetyl-D- in 23S rRNA protein] in 16S rRNA odhB thiosulfate oxidation III (multienzyme complex) assimilatory a 5'-phospho- a modified sn-glycero-3- nucleotide- 4-oxo-2-pentenal a fatty aldehyde diacetylchitobiose glucosamine sulfate reduction IV [DNA] nucleobase phosphoethanolamine selenate 3'-phosphate a [SoxY protein]-L-cysteine sulfate sulfate 2-oxoisovalerate decarboxylation to isobutanoyl-CoA adenylyltransferase: sat sulfate 3-methyl-2- 5,10-methylene- XLXG xyloglucan an [amino-group carrier protein]-C- (2R,3S)-3- a (2E,4Z)-2,4- adenosine 5'- pyrithiamine uroporphyrinogen-I a [protein] Ser/Thr a folate (S)-lactate adenylyltransferase: sat oxobutanoate tetrahydromethanopterin oligosaccharide terminal-γ-(L-ornithyl)-L-glutamate ethylphosphate isopropylmalate dienoyl-CoA D-ala an [apo BCAA phosphoselenate serine/threonine APS acetylornithine alkaline phosphatase: dihydrofolate 3-isopropylmalate 2,4-dienoyl- lactate 2- dehydrogenase a [SoxY protein]-S- uroporphyrinogen : glycine 6 monooxygenase: E2 protein] N alpha-ketoacid 3-methyl-2-oxobutanoate beta-glucosidase: transaminase: BVI01S_RS07035 reductase: dehydratase: CoA reductase: sulfosulfanyl-L-cysteine thiaminase decarboxylase: hemE BVI01S_RS13450 oxidase -lipoyl-L-lysine dehydrogenase adenylyl-sulfate hydroxymethyltransferase: BVI01S_RS12375 alkaline phosphatase: BVI01S_RS21070 leuC leuD BVI01S_RS10630 BVI01S_RS20185 BVI01S_RS12040 [+ 4 isozymes] ThiO: thiO subunit beta: kinase: cysC panB II: tenA an [amino-group carrier protein]- BVI01S_RS01420 (2S)-2- a (2E)-2- dihydrolipoyl selenite cytochrome c: C-terminal-γ-(L-glutamate 5- coproporphyrinogen I a [protein] (L-serine/L- a 7,8-dihydrofolate acetate pyruvate BVI01S_RS10800 BVI01S_RS10840 ethanol isopropylmalate enoyl-CoA dehydrogenase: PAPS XXXG xyloglucan semialdehyde-2-yl)-L-glutamate threonine) phosphate lpdA [+ 2 isozymes] cytochrome c: arg ammonium 2-(2-methylpyridin- 4-amino-2-methyl-5- D-galactopyranose 2-dehydropantoate THMPT oligosaccharide [+ 2 isozymes] BVI01S_RS19170 phosphoadenylyl- 3-yl)ethanol pyrimidinemethanol an [apo BCAA a [SoxY protein]-S- a [SoxY protein]-S sulfate reductase: carbamoyl an [apo BCAA dehydrogenase selenodiglutathione BVI01S_RS03330 argininosuccinate dehydrogenase 6 disulfanyl-L-cysteine phosphate synthase: E2 protein] N -S-[2- -sulfanyl-L-cysteine lyase: argH 2,5-diamino-6-(5- E2 protein] N 6 arginase: rocF BVI01S_RS12380 β XXLG xyloglucan an insertion sequence 3-(imidazol- methylpropanoyl]dihydrolipoyl- sulfite phospho-D-ribitylamino) a -D-galactoside oxaloacetate 2-hydroxypropiophenone [DNA] a cytosine in DNA (S)-benzoin (R)-lactate AIRs -dihydrolipoyl- BVI01S_RS12385 oligosaccharide element IS30 5-yl)lactate citrate synthase: citZ L-lysine pyrimidin-4(3H)-one (S)-benzoin forming DNA polymerase IV: : (S)-benzoin forming L-lactate D-2-hydroxyacid aminoimidazole L-lysine octaheme sulfite glutamine-hydrolyzing bifunctional DNA methylase: L-arginino-succinate L-ornithine citrate synthase/ benzil reductase: BVI01S_RS06600 BVI01S_RS21960 benzil reductase: dehydrogenase: dehydrogenase: riboside kinase: glutathioselenol reductase: carbamoyl-phosphate diaminohydroxyphosphoribosylaminopyrimidine beta-glucosidase: beta-glucosidase: BVI01S_RS00205 methylcitrate synthase: BVI01S_RS19300 [+ 2 isozymes] [+ 8 isozymes] BVI01S_RS19300 BVI01S_RS16595 BVI01S_RS15380 BVI01S_RS20140 TCA cycle TCA cycle I (prokaryotic) BVI01S_RS03350 synthase: carB carA deaminase/5-amino-6-(5-phosphoribosylamino) BVI01S_RS12040 BVI01S_RS12040 BVI01S_RS19760 1-phenyl-1,2- a 2'- an insertion a 5-methylcytosine 3-(imidazol- 2-oxo acid uracil reductase RibD: ribD 1,2-dihydroxypropane- benzil pyruvate AIR a [SoxY protein]-S-(2- hydrogen sulfide 5-amino-6-(5-phospho- propanedione deoxyribonucleoside sequence IS30 with in DNA 5-yl)pyruvate dehydrogenase assimilatory carbamoyl phosphate 1,2,3-tricarboxylate acetyl-CoA sulfodisulfanyl)-L-cysteine ornithine D-ribitylamino)uracil XXXG xyloglucan 5'-monophosphate integrated transposon subunit E2: sulfate reduction III D-galactopyranose a non galactosylated D-galactopyranose argininosuccinate carbamoyltransferase: argF oligosaccharide BVI01S_RS10805 hydrogen selenide synthase: BVI01S_RS14065 galactose acceptor oxaloacetate sulfate citrate synthase/ [+ 2 isozymes] L-citrulline methylcitrate synthase: sulfate glyphosate XLLG xyloglucan 3-(4- 967 UDP-N-acetyl- malate:quinone adenylyltransferase: sat sulfate activation phosphatidylglycerolphosphate a sialyloligosaccharide a cytosine β BVI01S_RS19760 degradation II oligosaccharide hydroxyphenyl) uroporphyrinogen-III an adenine in DNA α-D-glucosamine L- -lysine ferroheme o DHAP citrate for sulfonation (1-oleoyl, 2-palmitoyl) in 16S rRNA oxidoreductase: citrate synthase: citZ APS pyruvate 16S rRNA UDP-N- malate dehydrogenase: phosphatidylglycerophosphatase uroporphyrinogen-III type I restriction- putative beta-lysine aconitate BVI01S_RS02780 (cytosine(967)-C(5) acetylglucosamine heme A synthase: methylglyoxal BVI01S_RS04080 phosphoadenylyl- sulfate glyphosate A: BVI01S_RS13700 4-hydroxyphenylpyruvate C-methyltransferase: modification N-acetyltransferase: hydratase exo-alpha-sialidase: beta-glucosidase: )-methyltransferase system subunit M: 2-epimerase (non- BVI01S_RS18040 synthase: mgsA malate dehydrogenase: mdh sulfate reductase: sulfate phosphatidylglycerophosphatase dioxygenase: hppD cobA ablB AcnA: acnA BVI01S_RS02380 BVI01S_RS12040 RsmB: rsmB hydrolyzing): wecB (S)-malate citrate BVI01S_RS03330 adenylyltransferase: sat glycine A: BVI01S_RS15635 BVI01S_RS12915 UDP-N-acetyl-α- N6-acetyl- precorrin-2 a 5-methylcytosine 967 an N 6 -methyladenine ferroheme a methylglyoxal D-threo-isocitrate 1-oleoyl-2-palmitoyl- homogentisate L-β-lysine APS oxidase in 16S rRNA in DNA D-mannosamine sulfite phosphatidylglycerol XXXG xyloglucan ThiO: thiO N-acetylneuraminate an oligosaccharide D-galactopyranose fumarate hydratase: aconitate hydratase adenylyl-sulfate oligosaccharide BVI01S_RS02910 AcnA: acnA kinase: cysC (aminomethyl) glyoxylate class II fumarate 6 phosphonate a 5-carboxymethylaminomethyluridine 34 an N -L- a single 2'-deoxycytidine a uridine 55 D-ribulose (2S)- uridine phosphoenol 37 hydratase: fumC PAPS Leu threonylcarbamoyladenine a uridine in tRNA 5,6-dihydrouracil fumarate cis-aconitate hydrogen sulfide in tRNA L-homocysteine stranded DNA in tRNA 5-phosphate ethylmalonyl-CoA uridine kinase: pyruvate in tRNA : aconitate hydratase tRNA (uridine(34)/cytosine(34)/5- bifunctional homocysteine tRNA-dihydrouridine tRNA NAD-dependent ribulose-phosphate methylmalonyl- BVI01S_RS09985 tRNA deoxyribonuclease BVI01S_RS21510 pyruvate AcnA: acnA carboxymethylaminomethyluridine(34) S-methyltransferase/ synthase: pseudouridine(55) dihydropyrimidine 3-epimerase: CoA threonylcarbamoyladenosine IV: BVI01S_RS19140 deoxynucleoside kinase: uridine kinase: udk kinase: pyk -2'-O)- methyltransferase TrmL: trmL BVI01S_RS13185 synthase TruB: truB dehydrogenase BVI01S_RS07655 epimerase: mce cytochrome b558 subunit: Carboxylate Degradation dehydratase: BVI01S_RS19385 methylenetetrahydrofolate BVI01S_RS21505 UMP BVI01S_RS11545 a 5-carboxymethylaminomethyl- a cyclic N 6 -L- reductase: BVI01S_RS11590 a 5,6-dihydrouridine a pseudouridine 55 subunit PreA: preA D-xylulose (2R)- a 5'-phosphooligonucleotide dCMP pyruvate 2'-O-methyluridine 34 in tRNA Leu threonylcarbamoyladenosine in tRNA in tRNA uracil 5-phosphate ethylmalonyl-CoA propanoyl CoA met pyruvate decarboxylation to acetyl CoA I pyruvate fermentation to acetate IV glycolate and 37 in tRNA succinate D-threo-isocitrate degradation I NADP-dependent isocitrate glyoxylate a [pyruvate dehydrogenase pyruvate degradation II dehydrogenase: icd propanoyl-CoA pyruvate an [amino-group carrier protein]- N,N'- 2604 D-ribulose 5,6- cytidine ADP-forming succinate- 6 34 6-[1-hydroxyethyl]-7- 3-phenyl-2- a uridine β E2 protein] N -lipoyl-L-lysine pyruvatedehydrogenase a cytidine in tRNA γ dihydroxyacetone (S)-malate -D-allopyranose acyl-CoA glycolate methyl-7,8-dihydropterin C-terminal- -(L-glutamate 5- oxopropanoate diacetylchitobiose in 23S rRNA 5-phosphate dihydrothymine -CoA ligase: sucD sucC (acetyl-transferring) uridine kinase: carboxylase glycolate tRNA (uridine(34)/cytosine(34)/5- 2-amino-4-hydroxy-6- semialdehyde-2-yl)-L-glutamateN-acetyl-gamma- beta-N- 23S rRNA dihydroxyacetone NAD-dependent malate:quinone D-ribose E1 component 4-hydroxyphenylpyruvate : BVI01S_RS09985 subunit beta: dihydrolipoyl oxidase carboxymethylaminomethyluridine(34) hydroxymethyldihydropteridine glutamyl-phosphate acetylhexosaminidase: pseudouridine(2604) kinase subunit dihydropyrimidine oxidoreductase: pyranase: subunit alpha: pdhA dioxygenase: hppD BVI01S_RS02435 uridine kinase: udk BVI01S_RS06585 dehydrogenase: lpdA subunit -2'-O)- methyltransferase TrmL: trmL diphosphokinase: folK reductase: nagZ synthase RluF: rluF DhaK: dhaK dehydrogenase BVI01S_RS02780 rbsD succinyl-CoA 2-oxoglutarate subunit PreA: preA CMP acyl-CoA GlcD: glcD 34 [1-(2-amino-7-methyl-4-oxo- N-acetyl-D- 2604 D-ribulose-1,5- [+ 2 isozymes] pyruvate acetyl-CoA formate a 2'-O-methylcytidine an [amino-group carrierBVI01S_RS12360 protein]- (2-hydroxyphenyl) a pseudouridine DHAP β-D-allofuranose glyoxylate 7,8-dihydro-3H-pteridin- glucosamine thymine oxaloacetate carboxylase dehydrogenase in tRNA C-terminal-γ-(5-phospho- acetate in 23S rRNA bisphosphate subunit beta: 6-yl)]ethyl diphosphate (acetyl-transferring) phosphate malate L-glutamyl)-L-glutamate BVI01S_RS07945 E1 component acetyltransferase: pta 2-oxoglutarate (S)-methylmalonyl- a [pyruvate dehydrogenase synthase a [pyruvate dehydrogenase E2 subunit alpha: pdhA dehydrogenase CoA E2 protein] N 6 -S- A: aceB 6 acetyl phosphate E1 component: methylmalonyl- protein] N -dihydrolipoyl-L-lysine acetyldihydrolipoyl-L-lysine (S)-malate BVI01S_RS08925 CoA lipoate epimerase: mce acetyltransferase: acetate kinase: lpdA BVI01S_RS14050 superpathway of acetate (R)-methylmalonyl- utilization and formation CoA acetate methylmalonyl- acetate CoA acetate--CoA acetyl-CoA ligase: acsA mutase: scpA acetate kinase: succinyl-CoA BVI01S_RS14050 bile acids deconjugation acetyl phosphate acetyl-CoA glycocholate glycochenodeoxycholate

taurocholate taurochenodeoxycholate choloylglycine choloylglycine tauroursodeoxycholate phosphate acetyltransferase: pta hydrolase: hydrolase: D-gluconate BVI01S_RS05275 BVI01S_RS05275 degradation

D-gluconate cholate chenodeoxycholate ursodeoxycholate : gntK D-gluconate a branched- 6-phosphate chain a reduced a reduced a reduced an amino an amino amino acid plastocyanin plastocyanin a dicarboxylate a purine a sugar 6- plastocyanin acid acid a branched- a branched- an oxidized an oxidized phosphate a carbohydrate an oxidized an amino an amino L-ascorbate a basic an aliphatic a 2-hydroxy a sugar 6- a sugar 6- a sugar 6- chain chain D-glucose 6- D-glucose 6- plastocyanin plastocyanin an inorganic lactose 6'-phosphate an amino an amino an amino queuosine queuosine queuosine chromate chromate chromate a tricarboxylate a tricarboxylate a tricarboxylate ammonium a nucleoside a dipeptide a dipeptide a dipeptide pyrimidine 6-phosphate D-glucose amino acid a carbohydrate a carbohydrate a carbohydrate a carbohydrate an aromatic an aromatic phosphate phosphate plastocyanin uracil anion D-cellobiose 6'-phosphate acid acid acid acid acid sulfonate carboxylate phosphate phosphate phosphate amino acid amino acid predicted carboxylate carboxylate ABC predicted predicted predicted predicted ABC transporter ABC ABC PEP-driven cytochrome cytochrome RS03445 RS00960 RS06670 YfcC RS12625 RS18610 RS20945 RS00965 RS21310 RS05500 RS05655 RS12035 RS00330 transporter of RS08085 RS03220 RS18815 RS06570 RS15345 BrnQ BrnQ of a RS10960 RS10955 RS11725 RS21005 RS16650 RS07275 RS05045 RS05050 RS05055 RS07770 RS20770 RS01065 RS17050 RS05205 RS10965 RS13155 RS10310 RS07220 transporter transporter RS11435 RS10945 RS01760 RS15325 transporter c oxidase c oxidase a carbohydrate branched- of an of an of a sugar chain amino acid amino acid queuosine queuosine amino acid ammonium O O O 2 2 2 H O H O H O 2 2 2

an aliphatic a 2-hydroxy a branched- a branched- a branched- uracil an inorganic lactose L-ascorbate D-glucose a basic a sugar a sugar a sugar a sugar a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate queuosine chromate chromate chromate D-glucose D-glucose a tricarboxylate a tricarboxylate a tricarboxylate a nucleoside an amino an amino an amino an amino an amino an amino a dipeptide a dipeptide a dipeptide pyrimidine an aromatic an aromatic chain chain chain anion D-cellobiose amino acid sulfonate carboxylate a dicarboxylatean amino acid acid acid acid acid acid a purine carboxylate carboxylate amino acid amino acid amino acid acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.