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About your medicine Consult your doctor as soon as possible if any of • Inform your doctor if you are taking any other these additional effects occur, as they may indicate medications, in particular, antibiotics (e.g., Your doctor has prescribed colchicine for you:: more serious side effects: , ), and (cyanocobalamin). • Constipation What is this medicine used for? • Decreased appetite • Do not allow anyone else to take this • Difficulty urinating medication. This medicine is used for the treatment of acute • . It is also used for other conditions, including • Mouth sores the management of skin conditions, as determined by your doctor. How do I store this medicine? What precautions should I take? • Keep this medicine away from heat and How should I take this medicine? • Inform your doctor if you have liver or direct sunlight in a cool, dry place, out of disease; stomach problems (e.g., bleeding reach of children. Take each dose with a full glass of water. ulcer), blood disorders; dependence. • Do not keep this medicine with other

• For women: Tell your doctor if you are pregnant, medications in the same container. Keep What should I do if I forget a dose? plan to become pregnant, or are breast-feeding . each medicine separately in labeled

This medication is not recommended for use containers If you are directed by your doctor to take this during . Consult your doctor for more medicine regularly, take the missed dose as soon as details. you remember. If it is almost time for the next dose, skip the missed dose. When in doubt, consult your doctor or pharmacist: • Colchicine passes into breast milk. While there National Skin Centre have been no reports of harm to nursing infants, Do not double the next dose to make up for the 1 Mandalay Road, Singapore 308205. consult your doctor before breast-feeding. missed dose. Tel: 63508454

• For men: Colchicine can affect sperm

production, which may lower male .

Consult your doctor for more information. What possible side effects may it cause?

• Certain side effects of this medicine are not unusual Alcohol can decrease this drug's effectiveness. and may even disappear during treatment. If any of Limit alcohol consumption while taking this drug. the following effects persist or are severe, consult • your doctor. Kidney function declines as you grow older. This medication is removed by the kidneys. • Diarrhoea Therefore, elderly people may be at greater risk • Nausea or for side effects while using this drug, especially muscle problems. • Stomach upset

. Printed: Oct 2007

. PATIENT INFORMATION LEAFLET

COLCHICINE