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IUB No. Enzyme Name Source Approved in EC 1,4-Alpha-Glucan Bacillus Subtilis JECFA, Denmark, France, Brazil, 2.4.1.18 Branching Enzyme USA (GRAS Notice No

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IUB No. Enzyme Name Source Approved in EC 1,4-Alpha-Glucan Bacillus Subtilis JECFA, Denmark, France, Brazil, 2.4.1.18 Branching Enzyme USA (GRAS Notice No IUB No. Enzyme name Source Approved in EC 1,4-alpha-glucan Bacillus subtilis JECFA, Denmark, France, Brazil, 2.4.1.18 branching enzyme USA (GRAS Notice No. GRN 00274) Alpha-acetolactate Bacillus subtilis expressed in USA 21 CFR 173.115 decarboxylase Bacillus brevis EC 3.2.1.1 Alpha amylase Aspergillus niger Australia/New Zealand, Canada, France, Brazil, Mexico, USA (GRN 89) Aspergillus oryzae Australia/New Zealand, Canada, France, Brazil, Mexico, USA (GRN 90) Bacillus amyloliquefaciens Australia and New Zealand, Canada, Mexico, Brazil, USA 21 CFR 184.1148 Bacillus licheniformis Belgium, France, China, Japan, Denmark, Australia and New Zealand, Canada, Mexico, Brazil Bacillus licheniformis expressed Australia/New Zealand, Canada, in Bacillus licheniformis France, Brazil, Denmark, Mexico, USA GRAS Notice No. GRN 000079, JECFA Bacillus licheniformis and GRAS Notice No. GRN 00022, Bacillus amyloliquefaciens Brazil, Mexico expressed in Bacillus licheniformis Bacillus amyloliquefaciens Brazil, Denmark, France expressed in Bacillus licheniformis Bacillus megaterium expressed JECFA, Canada, Brazil, Mexico in Bacillus subtilis Bacillus stearothermophilus JECFA, Canada, Brazil, Mexico, USA 21 CFR 184.1012 Bacillus stearothermophilus Australia/New Zealand, Canada, expressed in Bacillus France, Brazil, Denmark, Mexico, licheniformis Japan, GRAS Notice No. GRN 000024 Bacillus stearothermophilus Australia/New Zealand, Canada, expressed in Bacillus subtilis France, Brazil, Denmark, Mexico Bacillus stearothermophilus Australia/New Zealand, Canada, (Geobacillus France, Europa, Brazil, Mexico, stearothermophilus) USA (GRN 594) Bacillus subtilis Australia and New Zealand, Canada, Mexico, Brazil, USA 21 CFR 184.1148 Rhizopus delemar Brazil Rhizopus oryzae Brazil, Mexico, USA GRAS Notice No. GRN 000090 Thermoccocales expressed in Brazil, USA (GRN126) Pseudomonas fluorecens Rhizomucor pusillus expressed Brazil, Denmark, France, Mexico, in Aspergillus niger Australia and New Zealand. Thermoactinomyces vulgaris expressed in B. subtilis Alicyclobacillus pohliae Canada, Denmark, Mexico expressed in Bacillus subtillis Cytophaga sp. expressed in USA (GRAS Notice No. GRN 604) Bacillus licheniformis Aspergillus kawachii expressed France in Trichoderma reesei Barley malt, malted cereals USA 21 CFR 184.1443a Pseudomonas fluorecens Canada, France Trichoderma reesei Denmark, France EC 4.1.1.5 Alfa-acetolactate Bacillus brevis expressed in Australia/New Zealand, Canada, decarboxylase Bacillus subtilis France, Europe, JECFA, Brazil, Denmark Bacillus brevis expressed in Brazil, Denmark, France, Mexico, Bacillus licheniformis Canada, GRAS Notice No. GRN 00587, Bacillus subtilis Australia, Denmark Bacillus amyloliquefaciens Australia Bacillus licheniformis Denmark EC 3.2.1.1 Alpha- Aspergillus niger Brazil, Mexico, New Zealand, galactosidase Australia Mortierella vinacea Brazil, Mexico, USA 21 CFR 173.145 Saccharomyces carlsbergensis Brazil, Mexico EC Maltogenic Bacillus stearothermophilus Brazil, Australia, Canada, China, 3.2.1.133 amylase expressed in Bacillus France, JECFA, Japan, Denmark, licheniformis Mexico, USA (GRN 751) Bacillus stearothermophilus Brazil, Mexico, Canada, China, expressed in Bacillus subtilis France, JECFA, USA (GRN 746 y GRN 751) Pseudomonas stutzeri Australia and New Zealand, expressed in Bacillus Canada, Mexico, Brazil licheniformis Geobacillus stearothermophilus Canada, China, France, JECFA, expressed in Bacillus subtilis Japan, Australia, Denmark, Brazil, Mexico, USA (GRN 751) EC 3.2.1.3 Amyloglucosidase Aspergillus niger var. awamori Canada, Brazil or Glucoamylase Aspergillus niger Australia and New Zealand, Canada, France, Brazil, Mexico, Japan, Denmark, USA (GRN 89) Aspergillus niger expressed in Brazil, Mexico, Australia and New Aspergillus niger Zealand, Canada, Mexico, USA (GRN 751) Aspergillus oryzae JECFA, Australia and New Zealand, Canada, France, Brazil, Mexico, USA (GRN 90) Rhizopus arrhizus Australia and New Zealand, Canada, Brazil, Mexico Rhizopus delemar Australia and New Zealand, Brazil Rhizopus niveus Mexico, Australia and New Zealand, Brazil, USA 21 CFR 173.110 Rhizopus oryzae Mexico, Australia and New Zealand, Brazil, USA (GRN 90) Talaromyces emersonii Brazil, Canada, China, Denmark, expressed in Aspergillus niger France, Mexico Trichoderma reesei Brazil Trametes cingulata expressed in Denmark, France Aspergillus niger Trichoderma reesei expressed Brazil, USA (GRN 372), JECFA in Trichoderma reesei Gloeophyllum trebeum Brazil, Denmark, France, Mexico expressed in Aspergillus niger Rhizopus delemar var. multiplicisporus Aspergillus fumigatus expressed Mexico in Trichoderma reesei Fusarium verticilloides Mexico expressed in Trichoderma reesei Penicillium oxalicum expressed Denmark, Mexico, in Aspergillus niger Glucoamylase de Aspergillus Canada niger 41SAM2-54 EC Amylomaltase Thermus thermophilus Australia/New Zealand, Canada, 2.4.1.25 expressed in Bacillus USA (GRN 507) amyloliquefaciens Aspergillus oryzae USA (GRAS Notice GRN No. 274) Aspergillus oryzae USA (GRN 274) Bacillus amyloliquefaciens Australia Aminoglycoside 3′- Eschericha coli expressed in USA (21 CFR 173.170) phosphotransferas Eschericha coli e II Eschericha coli expressed in USA 21 CFR 173.170 Eschericha coli EC Aminopeptidase Lactococcus lactis USA GRAS 3445, Brazil, 3.4.11.1 Australia/New Zealand, Canada Aspergillus oryzae Australia/New Zealand, China, France, Denmark, USA (GRN 90) Lactococcus lactis USA 21 CFR 184.1985 (Streptococcus lactis) EC 3.5.4.6 AMP deaminase Aspergillus melleus China, Denmark, France, Japan Streptomyces murinus Japan EC Arabinofuranosidas Talaromyces pinophilus Denmark, Mexico, USA (GRN 3.2.1.55 e expressed in Trichoderma 000680) reesei Aspergillus niger Australia, China, France, JECFA EC 3.5.1.1 Asparaginase Aspergillus niger expressed in Australia/New Zealand, Brazil, Aspergillus niger Canada, China, Denmark, France, JECFA, Mexico, USA (GRN 214) Aspergillus oryzae expressed in Australia/New Zealand Brazil, Aspergillus oryzae Mexico, Europe, Denmark, France, Canada, China, JECFA, Mexico, USA (GRN 201) Pyrococcus furiosus expressed Australia/New Zealand Brazil, in Bacillus subtilis Mexico, Europe, Denmark, Canada, USA (GRN 476), France Aspergillus niger Australia Aspergillus oryzae JECFA, Denmark, France, Brazil Bacillus subtilis Denmark, France, Brazil EC 3.4.23 Aspartic protease Cynara cardunculus L. USA (GRAS Notice GRN No. 551) Cynara cardunculus L. USA (GRN 551) EC 3.2.1.2 Beta-amylase Bacillus licheniformis Denmark Bacillus cereus Brazil Bacillus megaterium Brazil Bacillus subtilis Brazil Bacillus flexus expressed in Brazil, Mexico, Denmark, France, Bacillus licheniformis USA (GRAS) Cebeda 21 CFR 184.1443a EC 3.2.1.6 Beta-glucanase Aspergillus aculeatus Australia/New Zealand, Brazil, Canada, China, Denmark, France, Mexico Aspergillus niger Brazil, Canada, France Bacillus subtilis Brazil, Canada, France Disporotrichum Brazil, Canada, USA (GRN 482) dimorphosphorum Humicola insolens Brazil, Canada, France. USA (GRN 195) Penicillium emersonii Brazil Talaromyces emersonii Brazil, Canada, France, USA (GRN 479), Australia Trichoderma harzianum Brazil, Canada, France Trichoderma longibrachiatum Brazil Trichoderma reesei Brazil, Canada, France, Australia, JECFA Penicillium funiculosum USA (GRN 584) Bacillus subtilis expressed in USA (GRN 592) Bacillus subtilis Rasamsonia composticola Beta-glucosidase Aspergillus niger Brazil or cellobiase Trichoderma harzianum Brazil Trichoderma reesei Brazil EC Beta-glucosidase Apergillus niger Brazil, USA (GRN 750) 3.2.1.21 E.C. Bromelain Ananas comosus USA 21 CFR 184.1024 3.4.22.32 A. bracteatus L. USA 21 CFR 184.1024 EC 3.2.1.3 Carbohydrase Bacillus licheniformis Mexico Rhizopus oryzae USA (GRAS Notice GRN No. 90, 21 CFR 173.130) Aspergillus niger USA 21 CFR 173.120 EC 3.2.1.3 Diastase Rhizopus oryzae JECFA, Mexico, Brazil, USA (GRAS Notice GRN No. 90) 3.4.16.5 Carboxypeptidase Aspergillus niger expressed in Canada, Denmark, France, Mexico, C Aspergillus niger Russia, USA (GRN 435) EC Catalase Aspergillus niger Australia/New Zealand, Brazil, 1.11.1.6 Canada, China, France, USA (GRN 89), Mexico Micrococcus lysodeicticus USA 21 CFR 173.135, Canada, (micrococcus juteus) JECFA, Brazil, Mexico Aspergillus niger expressed in Australia/New Zealand, USA (GRN Aspergillus niger 89) Bovine liver USA 21 CFR 184.1034 EC 3.2.1.4 Cellulase Aspergillus niger Brazil, Mexico, Australia, New Zeland, Canada, JECFA, USA (GRN 89) Aspergillus oryzae Brazil, USA (GRN 90) Penicillium funiculosum Brazil, JECFA, USA (GRN 584) Rhizopus delemar Brazil Rhizopus oryzae Brazil Sporotrichum dimorphosporum Brazil Thielavia terrestris Brazil Trichoderma longibrachiatum Brazil, Australia/New Zealand, Canada, China, Denmark, France, Mexico Trichoderma reesei Brazil, Canada, USA 21 CFR 184.1250 Rasamsonia (Talaromyces) JECFA, USA (GRAS GRN 479) emersonii Trichoderma viride Australia EC Cyclodextrin Bacillus licheniformis Denmark, France 2.4.1.19 glucanotransferase Paenibacillus macerans Australia Thermoanaerobacter sp. expressed in Bacillus China, Denmark, France licheniformis EC D-Allulose 3- Arthrobacter globiformis USA (GRN 624) 5.1.3.30 epimerase expressed in E. coli K-12 W3110 EC Dextranase Bacillus subtilis Brazil 3.2.1.11 Chaetomium erraticum Brazil, Australia, New Zeland, Brazil, Denmark, USA GRAS GRN 000027 Chaetomium gracile Brazil Klebsiella aerogenes Brazil Penicillium funiculosum Brazil Penicillium lilacinum Brazil Branching enzyme Rhodothermus obamensis Brazil Milk clotting Endothia parasitica USA 21 CFR 173.150
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