EUROPEAN COMMISSION Brussels, 28 April 2020 REGISTER of FOOD
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EUROPEAN COMMISSION DIRECTORATE-GENERAL FOR HEALTH AND FOOD SAFETY Food and feed safety, innovation Food processing technologies and novel foods Brussels, 28 April 2020 REGISTER OF FOOD ENZYMES TO BE CONSIDERED FOR INCLUSION IN THE UNION LIST Article 17 of Regulation (EC) No 1332/20081 provides for the establishment of a Register of all food enzymes to be considered for inclusion in the Union list. In accordance with that Article, the Register includes all applications which were submitted within the initial period fixed by that Regulation and which comply with the validity criteria laid down in accordance with Article 9(1) of (EC) No 1331/2008 establishing a common authorisation procedure for food additives, food enzymes and food flavourings2. The Register therefore lists all valid food enzyme applications submitted until 11 March 2015 except those withdrawn by the applicant before that date. Applications submitted after that date are not included in the Register but will be processed in accordance with the Common Authorisation Procedure. The entry of a food enzyme in the Register specifies the identification, the name, the source of the food enzyme as provided by the applicant and the EFSA question number under which the status of the Authority’s assessment can be followed3. As defined by Article 3 of Regulation (EC) No 1332/2008, ‘food enzyme’ subject to an entry in the Register, refers to a product that may contain more than one enzyme capable of catalysing a specific biochemical reaction. In the assessment process, such a food enzyme may be linked with several EFSA question numbers. The present Register is not a list of authorised food enzymes. The enzymes in the Register are not authorised at Union level and have not necessarily already been evaluated by the Authority. Those enzymes that already have been evaluated by the Authority, did not all get a positive opinion. That does not affect the Register but will be taken into account at the time of adoption of the Union List in accordance with Article 7 of Regulation (EC) No 1331/2008. 1 Regulation (EC) No 1332/2008 of the European Parliament and of the Council of 16 December 2008 on food enzymes and amending Council Directive 83/417/EEC, Council Regulation (EC) No 1493/1999, Directive 2000/13/EC, Council Directive 2001/112/EC and Regulation (EC) No 258/97 (OJ L 354, 31.12.2008, p.7) 2 Regulation (EC) No 1331/2008 of the European Parliament and of the Council of 16 December 2008 establishing a common authorisation procedure for food additives, food enzymes and food flavourings (OJ L 354, 31.12.2008, p 1-6) 3 http://registerofquestions.efsa.europa.eu/roqFrontend/ListOfQuestionsNoLogin?2&unit=FIP&rawPanel=CEF&foodsectorarea=12 1 | 21 The Union List of food enzymes will be adopted once the Authority has issued an opinion on each food enzyme included in the Register in accordance with the procedure laid down in article 3 of Regulation (EC) No 1331/2008. Without prejudice to other applicable Union legislation, including Regulation (EC) No 178/20024, until the date of application of the Union list of food enzymes, national provisions in force concerning the placing on the market and use of food enzymes and food produced with food enzymes continue to apply in the Member States, in accordance with Article 24 of the Regulation on Food Enzymes. As per Article 4 of the Regulation on Food Enzymes, from the date of application of the Union list, only food enzymes included in that list may be placed on the EU market as such and used in foods, in accordance with the specifications and conditions of use provided for in the list. This Register was prepared by Commission services and does not commit the European Commission. Only the Court of Justice of the European Union is competent to authoritatively interpret Union law. 4 Regulation (EC) No 178/2002 of the European Parliament and of the Council of 28 January 2002 laying down the general principles and requirements of food law, establishing the European Food Safety Authority and laying down procedures in matters of food safety, OJ L 31, 1.2.2002, p. 1. 2 | 21 Name of 5 Name of the the IUBMB Name of the food production productio EFSA Q Commiss number Systematic name enzyme as organism as n strain Number ion ID (EC) submitted submitted as submitted 2013/19 1.1.3.4 β-D-glucose:oxygen 1- Glucose oxidase Aspergillus ZGL EFSA-Q- oxidoreductase niger 2013-01005 2013/22 1.1.3.4 β-D-glucose:oxygen 1- Glucose oxidase Aspergillus not EFSA-Q- oxidoreductase niger available 2013-01018 2015/151 1.1.3.4 β-D-glucose:oxygen 1- Glucose oxidase Aspergillus NZYM-KA EFSA-Q- oxidoreductase niger 2016-00134 2015/179 1.1.3.4 β-D-glucose:oxygen 1- Glucose oxidase Aspergillus DP-Aze23 EFSA-Q- oxidoreductase niger 2016-00144 2013/06 1.1.3.4 β-D-glucose:oxygen 1- Glucose oxidase Aspergillus NZYM-KP EFSA-Q- oxidoreductase oryzae 2013-00687 2015/121 1.1.3.4 β-D-glucose:oxygen 1- Glucose oxidase Penicillium PGO 19- EFSA-Q- oxidoreductase chrysogenum 162 2016-00533 2015/47 1.1.3.5 D-hexose:oxygen 1- Hexose oxidase Hansenula DP-Jza21 EFSA-Q- oxidoreductase polymorpha 2015-00406 2015/96 1.10.3.2 Benzenediol:oxygen Laccase Trametes AE-OR EFSA-Q- oxidoreductase hirusta 2015-00694 2015/105 1.10.3.3 L-ascorbate:oxygen L-Ascorbate Cucurbita not EFSA-Q- oxidoreductase oxidase pepo and applicable 2015-00825 Cucurbita moschata 2015/65 1.11.1.6 Hydrogen- Catalase Aspergillus AE-CN EFSA-Q- peroxide:hydrogen- niger 2015-00449 peroxide oxidoreductase 2015/119 1.11.1.6 Hydrogen- Catalase Aspergillus CTS 2093 EFSA-Q- peroxide:hydrogen- niger 2016-00532 peroxide oxidoreductase 2015/185 1.11.1.6 Hydrogen- Catalase Aspergillus DP-Azw58 EFSA-Q- peroxide:hydrogen- niger 2016-00274 peroxide oxidoreductase 2015/198 1.11.1.6 Hydrogen- Catalase Extracts of not EFSA-Q- peroxide:hydrogen- hog (pig) liver applicable 2017-00406 peroxide oxidoreductase 5 Identification number of the International Union of Biochemistry and Molecular Biology. 3 | 21 2015/158 1.11.1.6 Hydrogen- Catalase Porcine livers not EFSA-Q- peroxide:hydrogen- applicable 2016-00101 peroxide oxidoreductase 2015/26 1.11.1.7 Phenolic Peroxidase Aspergillus MOX EFSA-Q- donor:hydrogen- niger 2015-00274 peroxide oxidoreductase 2015/186 1.11.1.7 Phenolic Peroxidase Bovine milk - not EFSA-Q- donor:hydrogen- bovine applicable 2017-00041 peroxide cheese whey oxidoreductase - bovine colostrum 2013/10 1.11.1.7 Phenolic Peroxidase Soy bean not EFSA-Q- donor:hydrogen- hulls applicable 2013-00897 peroxide oxidoreductase 2015/169 2.3.2.13 Protein- Transglutaminase Streptomyces DSM EFSA-Q- glutamine:amine γ- mobaraensis 40587 2016-00657 glutamyltransferase 2015/188 2.3.2.13 Protein- Transglutaminase Streptomyces DSM EFSA-Q- glutamine:amine γ- mobaraensis 40587 2017-00615 glutamyltransferase 2015/10 2.3.2.13 Protein- Transglutaminase Streptoverticil S-8112 EFSA-Q- glutamine:amine γ- lium 2015-00095 glutamyltransferase mobaraense 2015/171 2.4.1.18 (1→4)-α-D- 1,4-alpha-Glucan Bacillus BR151 EFSA-Q- glucan:(1→4)-α-D- branching enzyme subtilis (pUAQ2) 2017-00408 glucan 6-α-D-[(1→4)-α- D-glucano]-transferase 2015/147 2.4.1.18 (1→4)-α-D- 1,4-alpha-Glucan Geobacillus TRBE14 EFSA-Q- glucan:(1→4)-α-D- branching enzyme stearothermo 2016-00100 glucan 6-α-D-[(1→4)-α- philus D-glucano]-transferase 2015/163 2.4.1.19 (1->4)-alpha-D- Cyclomaltodextrin Bacillus not EFSA-Q- glucan:(1->4)-alpha-D- glucanotransferase circulans available 2016-00523 glucan 4-alpha-D-[(1- >4)-alpha-D-glucano]- transferase (cyclizing) 2015/201 2.4.1.19 (1->4)-alpha-D- Cyclomaltodextrin Escherichia WCM105x EFSA-Q- glucan:(1->4)-alpha-D- glucanotransferase coli pCM703 2016-00530 glucan 4-alpha-D-[(1- >4)-alpha-D-glucano]- transferase (cyclizing) 2015/202 2.4.1.19 (1->4)-alpha-D- Cyclomaltodextrin Escherichia WCM105x EFSA-Q- glucan:(1->4)-alpha-D- glucanotransferase coli pCM6420 2016-00531 glucan 4-alpha-D-[(1- >4)-alpha-D-glucano]- 4 | 21 transferase (cyclizing) 2015/03 2.4.1.19 (1->4)-alpha-D- Cyclomaltodextrin Geobacillus St-88 EFSA-Q- glucan:(1->4)-alpha-D- glucanotransferase stearothermo 2015-00230 glucan 4-alpha-D-[(1- philus >4)-alpha-D-glucano]- transferase (cyclizing) 2015/88 2.4.1.19 (1->4)-alpha-D- Cyclomaltodextrin Geobacillus AE-KCGT EFSA-Q- glucan:(1->4)-alpha-D- glucanotransferase stearothermo 2015-00081 glucan 4-alpha-D-[(1- philus >4)-alpha-D-glucano]- transferase (cyclizing) 2015/175 2.4.1.19 (1->4)-alpha-D- Cyclomaltodextrin Geobacillus not EFSA-Q- glucan:(1->4)-alpha-D- glucanotransferase stearothermo available 2016-00863 glucan 4-alpha-D-[(1- philus >4)-alpha-D-glucano]- transferase (cyclizing) 2015/89 2.4.1.19 (1->4)-alpha-D- Cyclomaltodextrin Paenibacillus AE-CGT EFSA-Q- glucan:(1->4)-alpha-D- glucanotransferase alginolyticus 2015-00082 glucan 4-alpha-D-[(1- >4)-alpha-D-glucano]- transferase (cyclizing) 2015/199 2.4.1.25 (1→4)-α-D- 4-alpha- Bacillus MAS EFSA-Q- glucan:(1→4)-α-D- glucanotransferase amyloliquefac 2017-00405 glucan 4-α-D- iens glycosyltransferase 2015/128 2.4.1.25 (1→4)-α-D- 4-alpha- Geobacillus AE-SAS EFSA-Q- glucan:(1→4)-α-D- glucanotransferase pallidus 2016-00033 glucan 4-α-D- glycosyltransferase 2015/157 2.4.1.14 Sucrose:(1→6)[(1→3)]- Alternansucrase Leuconostoc NRRL B- EFSA-Q- 0 α-D-glucan 6(3)-α-D- citreum 30894 2016-00209 glucosyltransferase 2014/04 3.1.1.3 Triacylglycerol Triacylglycerol Aspergillus LFS EFSA-Q- acylhydrolase lipase niger 2014-00325 2015/22 3.1.1.3 Triacylglycerol Triacylglycerol Aspergillus NZYM-DB EFSA-Q- acylhydrolase lipase niger 2015-00234 2015/28 3.1.1.3 Triacylglycerol Triacylglycerol Aspergillus AE-L EFSA-Q- acylhydrolase lipase niger 2015-00276 2015/144 3.1.1.3 Triacylglycerol Triacylglycerol Aspergillus FL 108SC EFSA-Q- acylhydrolase lipase niger 2016-00099 2015/154 3.1.1.3 Triacylglycerol Triacylglycerol Aspergillus NL 151 EFSA-Q- acylhydrolase lipase niger 2016-00654 2015/63 3.1.1.3 Triacylglycerol Triacylglycerol Aspergillus FL100SC EFSA-Q- acylhydrolase lipase niger agg.