■ Streptococcus alactolyticus ■ Atopobium vaginae ■ Prevotella denticola ■ Candida famata ■ Streptococcus anginosus ■ Bacteroides caccae ■ Prevotella intermedia ■ Candida freyschussii ■ Streptococcus canis ■ Bacteroides eggerthii ■ Prevotella melaninogenica ■ Candida glabrata ■ Streptococcus constellatus ssp. ■ Bacteroides fragilis ■ Prevotella oralis ■ Candida guilliermondii constellatus ■ Bacteroides ovatus ■ Prevotella oris ■ Candida haemulonii ■ Streptococcus constellatus ssp. ■ Bacteroides stercoris ■ Propionibacterium acnes ■ Candida inconspicua / pharyngis ■ Bacteroides thetaiotaomicron ■ Propionibacterium granulosum Candida lambica ■ Streptococcus cristatus ■ Bacteroides uniformis ■ Propionibacterium propionicum ■ Candida intermedia ■ Streptococcus downei ■ Bacteroides vulgatus (Propionibacterium propionicus) ■ Candida kefyr ■ Streptococcus dysgalactiae ssp. ■ Bifidobacterium spp. ■ Staphylococcus saccharolyticus ■ Candida krusei ID & AST Cards dysgalactiae ■ Campylobacter (Bacteroides) ■ Trueperella pyogenes ■ Candida lipolytica ■ Streptococcus dysgalactiae ssp. ureolyticus (Arcanobacterium pyogenes) ■ Candida lusitaniae RELIABLE SAFE RAPID equisimilis ■ Clostridium barati ■ Turicella otitidis ■ Candida magnoliae ■ Streptococcus equi ssp. equi ■ Clostridium bifermentans ■ Veillonella spp. ■ Candida norvegensis ■ Streptococcus equi ssp. zooepidemicus ■ Clostridium butyricum ■ Candida parapsilosis ■ Streptococcus equinus ■ Clostridium cadaveris ■ Candida pelliculosa ■ Streptococcus gallolyticus ssp. ■ Clostridium chauvoei ■ Candida pulcherrima gallolyticus ■ Clostridium clostridiiforme NEISSERIA ■ Candida rugosa ■ Streptococcus gallolyticus ssp. ■ Clostridium difficile ■ Candida sake pasteurianus ■ Clostridium glycolicum IDENTIFICATION ■ Candida spherica ■ Streptococcus gordonii ■ Clostridium group ■ Candida tropicalis ■ Streptococcus hyointestinalis ■ Clostridium histolyticum VITEK 2 NH CARD ■ Candida utilis ■ 1. ■ Ayats J., Cisnal M., Lucena J., and Marin R. Analysis Streptococcus infantarius ssp. coli ■ Clostridium paraputrificum ■ Candida zeylanoides REF. 21346 of the Impact of Using a VITEK 2 COMPACT® System in (Str. lutetiensis) ■ Clostridium perfringens ■ Cryptococcus albidus ■ a Clinical Microbiology Laboratory: Comparison with the Streptococcus infantarius ssp. ■ Clostridium ramosum ■ Cryptococcus laurentii infantarius MicroScan WalkAway System®. ASM 2007; Poster C-158. 2. ■ Clostridium septicum ■ Cryptococcus neoformans ■ Barry J., Brown A., Ensor V., Lakhani U., Petts D., Warren ■ Streptococcus intermedius ■ Clostridium sordellii ■ ureae ■ Cryptococcus terreus REFERENCES C., Winstanley T. Comparative evaluation of the VITEK 2 ■ Streptococcus mitis / ■ Clostridium sporogenes ■ Aggregatibacter ■ Cryptococcus uniguttulatus Advanced Expert System (AES) in five UK hospitals. Journal Streptococcus oralis ■ Clostridium subterminale actinomycetemcomitans ■ Geotrichum klebahnii of Antimicrobial Chemotherapy, 2003; 51: 1191–1202. 3. ■ ■ Streptococcus mutans ■ Clostridium tertium ■ Aggregatibacter aphrophilus ■ Kloeckera spp. Blondel-Hill E., Jang W., Lee I., Borton N., Book L., Thomas ■ Streptococcus ovis ■ Collinsella aerofaciens ■ Aggregatibacter segnis ■ Kodamaea ohmeri E. Comparison of Phoenix™ and VITEK® 2 Compact for ■ Streptococcus parasanguinis Performance of Identification and Susceptibility Testing, ■ Corynebacterium amycolatum ■ Campylobacter coli ■ Malassezia furfur ■ Streptococcus pluranimalium Workflow, and Time to Report. ICAAC 2006; Poster D-691. ■ Corynebacterium diphtheriae ■ Campylobacter fetus ssp. fetus ■ Malassezia pachydermatis ■ Streptococcus pneumoniae 4. ■ Bobenchik A.M., Deak E., Hindler J.A., Charlton C.L., ■ Corynebacterium jeikeium ■ ssp. jejuni ■ Millerozyma farinosa (Pichia ■ Streptococcus porcinus Humphries R.M. Performance of VITEK® 2 for Antimicrobial Susceptibility Testing of ■ Corynebacterium minutissimum ■ Capnocytophaga spp. farinosa) ■ Streptococcus pseudoporcinus with VITEK® 2 (2009 FDA) and 2014 CLSI Breakpoints. Journal of Clinical Microbiology, 2014; 53(3):816- ■ Corynebacterium pseudodiphteriticum ■ ■ Prototheca wickerhamii 823. 5. ■ Bobenchik A.M, Hindler J.A., Giltner C.L., Saeki S., Humphries R.M. Performance of VITEK® 2 ■ Streptococcus pyogenes ■ Corynebacterium striatum ■ ■ Prototheca zopfii for Antimicrobial Susceptibility Testing of Staphylococcus spp. and Enterococcus spp. Journal of Clinical ■ Streptococcus salivarius spp. salivarius ■ Corynebacterium ulcerans ■ Gardnerella vaginalis ■ Rhodotorula glutinis / Microbiology, 2014; 52(2):392-397. 6. ■ Doat V., Roubille M., and Turner R. Analysis of the Comparative ■ Streptococcus salivarius spp. ■ Corynebacterium urealyticum ■ Haemophilus haemolyticus Rhodotorula mucilaginosa Workflow and Accuracy of the VITEK® 2 Compact and the Combination Mini-API®/Agar diffusion thermophilus ■ ■ Eggerthella lenta ■ ■ Rhodotorula minuta SIRSCAN® Method. ECCMID 2007; Poster P-1727. 7. Eigner U., Schmid A., Wild U., Bertsch D., Fahr ■ Streptococcus sanguinis RCS Lyon B 398 160 242 B 398 RCSthéra 160 Lyon A.M. Analysis of the Comparative Workflow and Performance Characteristics of the VITEK 2 and Phoenix ■ Eggerthella catenaformis ■ Haemophilus parahaemolyticus ■ Saccharomyces cerevisiae ■ Streptococcus sobrinus Systems. Journal of Clinical Microbiology, 2005; 43(8): 3829–3834. 8. ■ Galar A., Yuste J.R., Espinosa (Lactobacillus catenaformis) ■ Haemophilus parainfluenzae ■ Saprochaete capitata ■ Streptococcus suis l M., Guillén-Grima F., Hernáez-Crespo S., and Leiva J. Clinical and economic impact of rapid reporting ■ Eubacterium limosum ■ Kingella denitrificans (Geotrichum capitatum) ■ Streptococcus suis ll of bacterial identification and antimicrobial susceptibility results of the most frequently processed ■ Finegoldia magna ■ ■ Sporobolomyces salmonicolor ■ Streptococcus thoraltensis specimen types. Eur J Clin Microbiol Infect Dis, 2012; 31 (9): 2445-2452. 9. ■ Heller-Ono A. Ergonomic ■ Fusobacterium mortiferum ■ Moraxella (Branhamella) catarrhalis ■ Stephanoascus ciferrii ■ Streptococcus uberis Analysis Comparison of the VITEK® 2 and VITEK® 2 Compact with the Microscan WalkAway® 96 and ■ Fusobacterium necrophorum ■ Neisseria cinerea ■ Trichosporon asahii ■ Streptococcus vestibularis Phoenix™ For Work Flow Efficiency and the Likelihood of Distal Upper Extremity Strain. bioMerieux White ■ Fusobacterium nucleatum ■ Neisseria elongata ■ Trichosporon inkin Paper, 2008. 10. ■ Hooper M., Hill C., Hadwell V., Blondel-Hill E. Comparison of bioMerieux VITEK 2 ■ Vagococcus fluvialis ■ Fusobacterium varium ■ ■ Trichosporon mucoides XL, BD Phoenix, and Seimens MicroScan Walkaway96 plus choosing an identification and antimicrobial ■ Lactobacillus acidopihlus ■ Neisseria lactamica ■ Zygosaccharomyces bailii susceptibility testing system for a medium sized microbiology laboratory. ECCMID 2013; Poster P-1536. ■ ■ Lactobacillus buchneri ■ 11. LaBombardi V.J. Maximizing the Use of the Advanced Expert System™ to Improve Patient Care. bioMerieux White Paper, 2011. 12. ■ Larone D.H, Tucci L.J., Samide D.O. Time Study of Three Automated ■ Lactobacillus casei ■ Neisseria sicca MICROBIOLOGY WITH CONFIDENCE ANAEROBE Systems for the Identification and Susceptibility of : The MicroScan WalkAway 96, VITEK, and VITEK ■ Lactobacillus fermentum ■ Oligella urethralis CORYNEBACTERIA 2. ASM 2000; Poster C-279. 13. ■ Livermore DM., Struelens M., Amorim J., Baquero F., Bille J., Canton R., ■ Lactobacillus gasseri ■ Suttonella indologenes IDENTIFICATION Henning S., Gatermann S., Marchese A., Mittermayer H., Oakton KJ., Praplan F., Ramos H., Schito GC., Van ■ Lactobacillus hilgardii Eldere J., Vaerhaegen J., Verhoef J., and Visser MR. Multicentre evaluation of the VITEK 2 Advanced Expert VITEK 2 ANC CARD ■ Lactobacillus parabuchneri System for interpretive reading of antimicrobial resistance tests. Journal of Antimicrobial Chemotherapy, ■ Lactobacillus paracasei ■ REF. 21347 2002; 49 (2): 289–300. 14. Römmler W., Beer L., Kessler M., and Kaehler K. Analysis of the Comparative ■ Lactobacillus plantarum YEAST Workflow and ID/ AST Test Result Accuracy of the VITEK® 2 compact and the Phoenix™ Systems. ASM 2006; Poster C-123. 15. ■ Sanders CC., Peyret M., Moland ES., Cavalieri SJ., Shubert C., Thomson KS., ■ Microbacterium flavescens IDENTIFICATION 1) Burkholderia cepacia, Cronobacter ■ Micobacterium ssp sakazakii, Boeufgras JM., and Sanders WE. Potential Impact of the VITEK® 2 System and the Advanced Expert System™ on the Clinical Laboratory of a University-Based Hospital. Journal of Clinical Microbiology, 2001; ■ Actinobaculum schaalii ■ Parabacteroides distasonis 2) ssp enterica, VITEK 2 YST CARD 39 (7): 2379-2385. ■ Actinomyces bovis ■ Parabacteroides merdae REF. 21343 S.typhimurium, S.enteritidis, S.spp, ■ Actinomyces israelii ■ Parvimonas micra S.ser.Paratyphi B, S.ser.Paratyphi C 3) Serratia grimesii, Ser.liquefaciens, ■ Actinomyces meyeri ■ Peptoniphilus asaccharolyticus Ser.proteamaculans ssp proteamaculans ■ Actinomyces naeslundii ■ Peptoniphilus indolicus 4) , Shi.boydii, ■ Actinomyces neuii ■ Peptostreptococcus anaerobius bioMérieux S.A. ■ Candida albicans Shi.dysenteriae ■ Actinomyces odontolyticus ■ Porphyromonas gingivalis 69280 Marcy l’Etoile ■ Candida boidinii 5) Burkholderia cepacia, B.multivorans, ■ Actinomyces turicensis ■ Prevotella bivia ■ Candida catenulata B.stabilis, B.vietnamiensis France ■ Anaerococcus prevotii ■ Prevotella buccae ■ Candida colliculosa 6) Moraxella lacunata, M.nonliquefaciens, Tel.: +33 (0)4 78 87 20 00 ■ Arcanobacterium haemolyticum ■ Prevotella disiens M.osloensis ■ Candida dubliniensis Fax: +33 (0)4 78 87 20 90

03-16 / 9310459/002/GB/E / Document and/or pictures not legally binding. Modifications by bioMérieux can be made without prior notice BIOMÉRIEUX, / 9310459/002/GB/E the blue logo, Advanced Expert03-16 API, System, VITEK are used, pending and/or registered trademarks belonging to bioMérieux, or one of its subsidiaries, companies / CLSI is a trademark belonging to Clinical Laboratory and Standards Institute, Inc. / Any other name or trademark is the property 620 399 of its respective owner / Photos: N. Bouchut, C. Ganet, / / bioMérieux S.A. 673 RCSGettyimages / Printed in France Lyon www.biomerieux.com ■ Salmonella entérica ssp arizonae ■ ■ Erysipelothrix rhusiopahiae ■ Salmonella entérica ssp diarizonae ■ Pasteurella pneumotropica ■ Facklamia hominis GRAM NEGATIVE ■ Salmonella group (2) ■ Pasteurella testudinis ■ Gardnerella vaginalis IDENTIFICATION ■ Salmonella ser. Gallinarum ■ Photobacterium damselae ■ Gemella bergeri ■ Salmonella ser. paratyphi A ■ ■ Gemella haemolysans VITEK® 2 GN CARD ■ Salmonella ser. typhi ■ Pseudomonas alcaligenes ■ Gemella morbillorum RAPID, FLEXIBLE, EFFICIENT REF. 21341 ■ Serratia ficaria ■ Pseudomonas fluorescens ■ Gemella sanguinis ■ Serratia fonticola ■ Pseudomonas luteola ■ Globicatella sanguinis ■ Serratia liquefaciens group (3) ■ Pseudomonas mendocina ■ Globicatella sulfidifaciens ■ ■ Pseudomonas oleovorans ■ Granulicatella adiacens ■ Serratia odorifera ■ Pseudomonas oryzihabitans ■ Granulicatella elegans Each self-contained, disposable test card provides rapid ENTEROBACTERIACEAE ■ Serratia plymuthica ■ Pseudomonas putida ■ Helcococcus kunziii ■ Serratia rubidaea ■ Pseudomonas stutzeri ■ ■ Budvicia aquatica Kocuria kristinae ■ Shigella group (4) ■ Ralstonia mannitolilytica ■ and accurate species-level identification or ■ Buttiauxella agrestis Kocuria rhizophila ■ ■ Ralstonia pickettii ■ Kocuria rosea * ■ Cedecea davisae ■ Yersinia aldovae ■ Rhizobium radiobacter ■ susceptibility results with accurate MICs based on ■ Cedecea lapagei Kocuria varians ■ /frederiksenii ■ Roseomonas gilardii ■ Lactococcus garvieae ** *** ■ Citrobacter amalonaticus ■ Yersinia intermedia ■ Shewanella algae ■ reference CLSI and ISO MIC methods and EUCAST , ■ Citrobacter braakii Lactococcus lactis ssp cremoris ■ Yersinia kristensenii ■ Shewanella putrefaciens ■ Lactococcus lactis ssp lactis **** ■ Citrobacter farmeri 1,3,4,5,7,8,10 ■ ■ Sphingobacterium multivorum ■ US FDA , or CLSI breakpoint interpretations . ■ Lactococcus raffinolactis ■ Yersinia pseudotuberculosis ■ Sphingobacterium spiritivorum ■ ■ Leuconostoc citreum ■ Yersinia ruckeri ■ Sphingobacterium thalpophilum ■ Innovative and flexible design: ■ Citrobacter sedlakii Leuconostoc lactis ■ Yokenella regensburgei ■ Sphingomonas paucimobilis ■ ■ Citrobacter youngae Leuconostoc mesenteroides ssp. (1) ■ Stenotrophomonas maltophilia • Each card contains microwells with ID biochemicals or AST antimicrobials ■ Cronobacter sakazakii group cremoris ■ ■ ■ Edwardsiella hoshinae NON-ENTEROBACTERIACEAE Leuconostoc mesenteroides ssp. ■ • Ready and simple to use ■ Edwardsiella tarda ■ Achromobacter denitrificans dextranicum ■ Vibrio fluvialis ■ • Pre-applied barcodes for maximum traceability ■ Enterobacter aerogenes ■ Achromobacter xylosoxidans Leuconostoc mesenteroides ssp. ■ Vibrio metschnikovii ■ Enterobacter amnigenus 1 ■ complex mesenteroides • EUCAST and CLSI compliant AST formulations available ■ Vibrio mimicus ■ Enterobacter amnigenus 2 ■ Acinetobacter haemolyticus ■ Leuconostoc pseudomesenteroides ■ ■ Enterobacter asburiae ■ Acinetobacter junii ■ Listeria grayi 3,9,10 ■ Up to 50% fewer preparation steps than other systems, : ■ Enterobacter cancerogenus ■ Acinetobacter lwoffii ■ Listeria innocua FOCUS ■ Enterobacter cloacae complex (1) ■ Actinobacillus radioresistens ■ Listeria ivanovii • Inoculation with a simple, standardised suspension of organism in saline ■ Enterobacter gergoviae ■ Actinobacillus ursingii HIGHLY PATHOGENIC ■ Listeria monocytogenes • No reagent addition ■ ■ Actinobacillus ureae ORGANISMS ■ Listeria seeligeri ■ Escherichia coli O157 ■ / ■ Brucella melitensis ■ Listeria welshimeri ON WHAT MATTERS ■ ■ ■ Micrococcus luteus/lylae Escherichia fergusonii Aeromonas caviae Unique, safe, closed consumable: ■ Escherichia hermannii ■ Aeromonas salmonicida ■ Burkholderia pseudomallei ■ Pediococcus acidilactici ® ■ Escherichia vulneris ■ Aeromonas sobria ■ Escherichia coli O157 ■ Pediococcus pentosaceus Designed for VITEK 2 automated systems, • Optimal for user safety ■ Ewingella americana ■ ■ ■ Rothia mucilaginosa ■ Staphylococcus arlettae ® • No aerosols, splattering, or spills ■ Hafnia alvei ■ Alcaligenes faecalis ssp. faecalis ■ Yersinia pestis VITEK 2 identification (ID) and ■ ■ bronchiseptica ■ Staphylococcus aureus • Small, lightweight cards save on contaminated disposal costs and ■ ■ Bordetella hinzii ■ Staphylococcus auricularis susceptibility (AST) cards provide reliable and storage space ssp ozaenae ■ Bordetella trematum ■ Staphylococcus capitis ■ Klebsiella pneumoniae ■ Brevundimonas diminuta/vesicularis ■ Staphylococcus caprae ssp pneumoniae ■ Brucella melitensis GRAM POSITIVE ■ Staphylococcus carnosus ssp. carnosus accurate results for clinically important bacteria BROAD AND EXPANDING ID/AST TEST MENU (5) ■ ■ Klebsiella pneumoniae ■ Burkholderia cepacia group IDENTIFICATION Staphylococcus chromogenes 1,2,4,5 ssp rhinoscleromatis ■ Burkholderia gladioli ■ Staphylococcus cohnii ssp. cohnii ® and yeasts . ■ Kluyvera ascorbata ■ Burkholderia mallei VITEK 2 GP CARD ■ Staphylococcus cohnii ssp. urealyticus IDENTIFICATION CARD TYPES: ANTIBIOTIC SUSCEPTIBILITY CARD TYPES*: ■ Kluyvera cryocrescens ■ Burkholderia pseudomallei REF. 21342 ■ Staphylococcus epidermidis ■ Kluyvera intermedia ■ Chromobacterium violaceum ■ Staphylococcus equorum ■ GN (Gram negative bacilli) ■ Results You Can Trust Gram negative Bacilli ■ Leclercia adecarboxylata ■ Chryseobacterium gleum ■ Staphylococcus gallinarum † 156 organisms 76 antimicrobials and ESBL test ■ Moellerella wisconsensis ■ Chryseobacterium indologenes ■ Staphylococcus haemolyticus The VITEK® 2 Advanced Expert System™ software lets you focus your ■ GP (Gram positive cocci & bacilli) ■ Staphylococci &/or Enterococci ■ Morganella morganii ssp. morganii ■ Comamonas testosteroni ■ Abiotrophia defectiva ■ Staphylococcus hominis ssp. hominis time where it is most required in the lab. The Advanced Expert System 120 organisms 55 antimicrobials, 4 high level aminoglycoside ■ Morganella morganii ssp. sibonii ■ Cupriavidus pauculus ■ Aerococcus urinae ■ Staphylococcus hominis ssp. ■ Pantoea agglomerans ■ Delftia acidovorans ■ Aerococcus viridans novobiosepticus validates every result and quickly identifies those truly needing a ■ †† ANC (anaerobes & Corynebacteria) screens and ICR test ■ ■ ■ Alloiococcus otitis ■ Staphylococcus hyicus Microbiologist’s valuable time and attention. This allows the majority of Pantoea spp. Elizabethkingia meningoseptica 89 organisms ■ Streptococci ■ ■ Francisella tularensis ■ Dermacoccus nishinomiyaensis / ■ Staphylococcus intermedius results to be quickly and confidently reported to clinicians without need for ■ 14 antimicrobials and ICR test and gentamicin synergy ■ Proteus hauseri ■ Grimontia hollisae Kytococcus sedentarius ■ Staphylococcus kloosii 2,8,11,13,15 NH (Neisseria & Haemophilus) review . ■ ■ ■ ■ Staphylococcus lentus 26 organisms ■ Streptococcus pneumoniae Mannheimia haemolytica Enterococcus avium ■ Proteus penneri ■ Methylobacterium spp. ■ Enterococcus casseliflavus ■ Staphylococcus lugdunensis ■ 23 antimicrobials (6) Efficiency Through Automation YST (Yeast) ■ ■ Moraxella group ■ Enterococcus cecorum ■ Staphylococcus pseudintermedius 50 organisms ■ YST (Yeast) ■ Providencia alcalifaciens ■ Myroides spp. ■ Enterococcus columbae ■ Staphylococcus saprophyticus ® VITEK 2 cards offer the shortest preparation time in the industry, 6 antimicrobials ■ Providencia rettgeri ■ Neisseria animaloris/zoodegmatis ■ Enterococcus durans ■ Staphylococcus schleiferi considerably reducing labor costs1,3,7,9,10,14. They also have the least ■ Providencia rustigianii ■ Ochrobactrum anthropi ■ Enterococcus faecalis ■ Staphylococcus sciuri contaminated waste, offering up to 64% cost savings for disposal *Availability pending registrations as required by local regulatory authority ■ Providencia stuartii ■ Oligella ureolytica ■ Enterococcus faecium ■ Staphylococcus simulans ■ ■ ■ Enterococcus gallinarum ■ Staphylococcus vitulinus compared to other systems6,10,12.The cards provide increased Rahnella aquatilis Paracoccus yeei ■ Raoultella ornithinolytica ■ Pasteurella aerogenes ■ Enterococcus hirae ■ Staphylococcus warneri standardization and automated, same-day results helping clinicians to * Minimum Inhibitory Concentration ****Food and Drug Administration ** Clinical & Laboratory Standards Institute † Extended-spectrum-beta-lactamase ■ Raoultella planticola ■ Pasteurella canis ■ Enterococcus raffinosus ■ Staphylcoccus xylosus 2,3 optimise antibiotic therapy sooner . *** European Committee on Antimicrobial Susceptibility Testing †† Inducible clindamycin resistance ■ Roseomonas gilardii ■ Pasteurella dagmatis ■ Enterococcus saccharolyticus ■ Streptococcus agalactiae