SAFETY DATA SHEET

Crude Butadiene Version 4.0 Revision Date 2021-03-30

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product information Product Name : Crude Butadiene Material : 1120922, 1037102, 1015401

Use : Chemical intermediate

Company : Chevron Phillips Chemical Company LP 10001 Six Pines Drive The Woodlands, TX 77380

Emergency telephone:

Health: 866.442.9628 (North America) 1.832.813.4984 (International) Transport: CHEMTREC 800.424.9300 or 703.527.3887(int'l) Asia: CHEMWATCH (+612 9186 1132) China: 0532 8388 9090 EUROPE: BIG +32.14.584545 (phone) or +32.14583516 (telefax) Mexico CHEMTREC 01-800-681-9531 (24 hours) South America SOS-Cotec Inside Brazil: 0800.111.767 Outside Brazil: +55.19.3467.1600 Argentina: +(54)-1159839431

Responsible Department : Product Safety and Toxicology Group E-mail address : [email protected] Website : www.CPChem.com

SECTION 2: Hazards identification

Classification of the substance or mixture This product has been classified in accordance with the hazard communication standard 29 CFR 1910.1200; the SDS and labels contain all the information as required by the standard.

Classification : Flammable gases, Category 1 Gases under pressure, Liquefied gas Acute toxicity, Category 4, Oral Skin irritation, Category 2 Eye irritation, Category 2A Germ cell mutagenicity, Category 1B Carcinogenicity, Category 1A

SDS Number:100000014664 1/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

Specific target organ toxicity - single exposure, Category 3, Central nervous system

Labeling

Symbol(s) :

Signal Word : Danger

Hazard Statements : H220: Extremely flammable gas. H280: Contains gas under pressure; may explode if heated. H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H336: May cause drowsiness or dizziness. H340: May cause genetic defects. H350: May cause cancer.

Precautionary Statements : Prevention: P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P210 Keep away from heat/ sparks/ open flames/ hot surfaces. No smoking. P261 Avoid breathing dust/fume/gas/mist/vapors/spray. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. Response: P301 + P312 + P330 IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. Rinse mouth. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P340 + P312 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/ doctor if you feel unwell. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P332 + P313 If skin irritation occurs: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention. P362 Take off contaminated clothing and wash before reuse. P377 Leaking gas fire: Do not extinguish, unless leak can be stopped safely. P381 Eliminate all ignition sources if safe to do so. Storage: P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P410 + P403 Protect from sunlight. Store in a well-ventilated

SDS Number:100000014664 2/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

place. Disposal: P501 Dispose of contents/ container to an approved waste disposal plant.

Carcinogenicity: IARC Group 1: Carcinogenic to humans 1,3-Butadiene 106-99-0 Benzene 71-43-2 Group 2B: Possibly carcinogenic to humans Isoprene 78-79-5 NTP Known to be human carcinogen 1,3-Butadiene 106-99-0 Benzene 71-43-2 Reasonably anticipated to be a human carcinogen Isoprene 78-79-5

SECTION 3: Composition/information on ingredients

Synonyms : 1,3-Butadiene Butadiene, 1,3- Butadiene Feedstock Crude C4

Molecular formula : UVCB

Component CAS-No. Weight % Gases (petroleum), light steam- 68955-28-2 100 cracked, butadiene conc. 1,3-Butadiene 106-99-0 10 - 80 n-Butane 106-97-8 0 - 60 Isobutane 75-28-5 0 - 30 Isobutylene 115-11-7 0 - 15 1-Butene 106-98-9 0 - 15 cis-2-Butene 590-18-1 0 - 10 trans-2-Butene 624-64-6 0 - 10 Isopentane 78-78-4 0 - 5 n-Pentane 109-66-0 0 - 5 Cyclopentadiene 542-92-7 0 - 5 Isoprene 78-79-5 0 - 5 Cyclopentane 287-92-3 0 - 5 2-methyl-2-butene 513-35-9 0 - 5 Benzene 71-43-2 0.1 - 1

SECTION 4: First aid measures

General advice : Move out of dangerous area. Show this material safety data sheet to the doctor in attendance.

If inhaled : Consult a physician after significant exposure. If unconscious, SDS Number:100000014664 3/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

place in recovery position and seek medical advice.

In case of skin contact : If skin irritation persists, call a physician. If on skin, rinse well with water. If on clothes, remove clothes.

In case of eye contact : Immediately flush eye(s) with plenty of water. Remove contact lenses. Protect unharmed eye. Keep eye wide open while rinsing. If eye irritation persists, consult a specialist.

If swallowed : Induce vomiting immediately and call a physician. Keep respiratory tract clear. Do not give milk or alcoholic beverages. Never give anything by mouth to an unconscious person. If symptoms persist, call a physician. Take victim immediately to hospital.

SECTION 5: Firefighting measures

Flash point : -76°C (-105°F)

Autoignition temperature : No data available

Suitable extinguishing : Alcohol-resistant foam. Carbon dioxide (CO2). Dry chemical. media

Unsuitable extinguishing : High volume water jet. media

Specific hazards during fire : Do not allow run-off from fire fighting to enter drains or water fighting courses.

Special protective : Wear self-contained breathing apparatus for firefighting if equipment for fire-fighters necessary.

Further information : Collect contaminated fire extinguishing water separately. This must not be discharged into drains. Fire residues and contaminated fire extinguishing water must be disposed of in accordance with local regulations. For safety reasons in case of fire, cans should be stored separately in closed containments. Use a water spray to cool fully closed containers.

Fire and explosion : Do not spray on a naked flame or any incandescent material. protection Take necessary action to avoid static electricity discharge (which might cause ignition of organic vapors). Use only explosion-proof equipment. Keep away from open flames, hot surfaces and sources of ignition.

Hazardous decomposition : Carbon oxides. products

SECTION 6: Accidental release measures

Personal precautions : Use personal protective equipment. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapors accumulating to form explosive concentrations. Vapors can accumulate in low

SDS Number:100000014664 4/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

areas.

Environmental precautions : Prevent product from entering drains. Prevent further leakage or spillage if safe to do so. If the product contaminates rivers and lakes or drains inform respective authorities.

SECTION 7: Handling and storage

Handling

Advice on safe handling : Do not breathe vapors/dust. Avoid exposure - obtain special instructions before use. Avoid contact with skin and eyes. For personal protection see section 8. Smoking, eating and drinking should be prohibited in the application area. Take precautionary measures against static discharges. Provide sufficient air exchange and/or exhaust in work rooms. Open drum carefully as content may be under pressure. Dispose of rinse water in accordance with local and national regulations.

Advice on protection : Do not spray on a naked flame or any incandescent material. against fire and explosion Take necessary action to avoid static electricity discharge (which might cause ignition of organic vapors). Use only explosion-proof equipment. Keep away from open flames, hot surfaces and sources of ignition.

Storage

Requirements for storage : Prevent unauthorized access. No smoking. Keep container areas and containers tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Observe label precautions. Electrical installations / working materials must comply with the technological safety standards.

Use : Chemical intermediate

SECTION 8: Exposure controls/personal protection

Ingredients with workplace control parameters

US Components Basis Value Control parameters Note 1,3-Butadiene ACGIH TWA 2 ppm, A2, OSHA Z-1 TWA 1 ppm, OSHA Z-1 STEL 5 ppm, OSHA CARC PEL 1 ppm, OSHA 29 CFR TWA 1 ppm, 1910.1051(c) OSHA CARC STEL 5 ppm, OSHA 29 CFR STEL 5 ppm, 1910.1051(c) n-Butane OSHA Z-1-A TWA 800 ppm, 1,900 mg/m3 ACGIH STEL 1,000 ppm, CNS impair, EX, ACGIH STEL 1,000 ppm, Isobutane ACGIH STEL 1,000 ppm, CNS impair, EX, ACGIH STEL 1,000 ppm, Isobutylene ACGIH TWA 250 ppm, A4, 1-Butene ACGIH TWA 250 ppm, cis-2-Butene ACGIH TWA 250 ppm, trans-2-Butene ACGIH TWA 250 ppm, Isopentane ACGIH TWA 1,000 ppm, n-Pentane OSHA Z-1 TWA 1,000 ppm, 2,950 mg/m3 SDS Number:100000014664 5/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

OSHA Z-1-A TWA 600 ppm, 1,800 mg/m3 OSHA Z-1-A STEL 750 ppm, 2,250 mg/m3 ACGIH TWA 1,000 ppm, Cyclopentadiene ACGIH TWA 0.5 ppm, OSHA Z-1 TWA 75 ppm, 200 mg/m3 OSHA Z-1-A TWA 75 ppm, 200 mg/m3 ACGIH STEL 1 ppm, ACGIH TWA 0.5 ppm, URT irr, LRT irr, eye irr, ACGIH STEL 1 ppm, Isoprene US WEEL TWA 2 ppm, Cyclopentane ACGIH TWA 600 ppm, OSHA Z-1-A TWA 600 ppm, 1,720 mg/m3 Benzene ACGIH TWA 0.5 ppm, A1, Skin, ACGIH STEL 2.5 ppm, A1, Skin, OSHA Z-1-A TWA 1 ppm, OSHA Z-1-A CEIL 5 ppm, OSHA Z-2 Peak 50 ppm, OSHA 29 CFR TWA 1 ppm, 1910.1028(c) OSHA 29 CFR STEL 5 ppm, 1910.1028(c) OSHA CARC PEL 1 ppm, OSHA CARC STEL 5 ppm, A1 Confirmed human carcinogen A2 Suspected human carcinogen A4 Not classifiable as a human carcinogen CNS impair Central Nervous System impairment EX Explosion hazard: the substance is a flammable asphyxiant or excursions above the TLV ® could approach 10% of the lower explosive limit. eye irr Eye irritation LRT irr Lower Respiratory Tract irritation Skin Danger of cutaneous absorption URT irr Upper Respiratory Tract irritation

Hazardous components without workplace control parameters Immediately Dangerous to Life or Health Concentrations (IDLH)

Substance name CAS-No. Control parameters Update 1,3-Butadiene 106-99-0 Immediately Dangerous to Life or Health 2017-02-03 Concentration Value 2000 parts per million n-Butane 106-97-8 Immediately Dangerous to Life or Health 2017-02-03 Concentration Value 1600 parts per million n-Pentane 109-66-0 Immediately Dangerous to Life or Health 1995-03-01 Concentration Value 1500 parts per million Cyclopentadiene 542-92-7 Immediately Dangerous to Life or Health 1995-03-01 Concentration Value 750 parts per million Benzene 71-43-2 Immediately Dangerous to Life or Health 1995-03-01 Concentration Value 500 parts per million

Biological exposure indices

US Substance name CAS-No. Control parameters Sampling time Update 1,3-Butadiene 106-99-0 1,2 Dihydroxy-4-(N-acetylcysteinyl)- End of shift (As 2010-03-01 butane: 2.5 mg/l Background soon as possible (Urine) Semi-quantitative () after exposure ceases) Mixture of N-1 and N- Not critical 2010-03-01 2(hydroxybutenyl)valine: 2.5 picomoles per gram Hemoglobin Semi-quantitative (Hemoglobin (Hb) adducts in blood)

SDS Number:100000014664 6/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

Benzene 71-43-2 S-Phenylmercapturic acid: 25 End of shift (As 2010-03-01 µg/g creatinine Background (Urine) soon as possible after exposure ceases) t,t-Muconic acid: 500 µg/g End of shift (As 2010-03-01 creatinine Background (Urine) soon as possible after exposure ceases) Engineering measures Adequate ventilation to control airborned concentrations below the exposure guidelines/limits. Consider the potential hazards of this material (see Section 2), applicable exposure limits, job activities, and other substances in the work place when designing engineering controls and selecting personal protective equipment. If engineering controls or work practices are not adequate to prevent exposure to harmful levels of this material, the personal protective equipment listed below is recommended. The user should read and understand all instructions and limitations supplied with the equipment since protection is usually provided for a limited time or under certain circumstances.

Personal protective equipment

Respiratory protection : Wear a supplied-air NIOSH approved respirator unless ventilation or other engineering controls are adequate to maintain minimal oxygen content of 19.5% by volume under normal atmospheric pressure. Wear a NIOSH approved respirator that provides protection when working with this material if exposure to harmful levels of airborne material may occur, such as:. Use a positive pressure, air-supplying respirator if there is potential for uncontrolled release, aerosolization, exposure levels are not known, or other circumstances where air-purifying respirators may not provide adequate protection.

Hand protection : The suitability for a specific workplace should be discussed with the producers of the protective gloves. Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. Also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion, and the contact time. Gloves should be discarded and replaced if there is any indication of degradation or chemical breakthrough.

Eye protection : Eye wash bottle with pure water. Safety glasses.

Skin and body protection : Choose body protection in relation to its type, to the concentration and amount of dangerous substances, and to the specific work-place. Wear as appropriate:. Flame retardant antistatic protective clothing. Workers should wear antistatic footwear.

Hygiene measures : When using do not eat or drink. When using do not smoke. Wash hands before breaks and at the end of workday.

SECTION 9: Physical and chemical properties

Information on basic physical and chemical properties Appearance Form : Liquefied gas Physical state : Gaseous Color : Colorless SDS Number:100000014664 7/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

Odor : Odorless

Safety data Flash point : -76°C (-105°F)

Lower explosion limit : 2 %(V)

Upper explosion limit : 12 %(V)

Oxidizing properties : No

Autoignition temperature : No data available

Molecular formula : UVCB

Molecular weight : Not applicable

pH : No data available

Pour point : No data available

Boiling point/boiling range : -11-28°C (12-82°F)

Vapor pressure : 64.00 PSI at 37.8°C (100.0°F)

Relative density : 0.63 at 16 °C (61 °F)

Water solubility : negligible

Partition coefficient: n- : No data available octanol/water Viscosity, kinematic : No data available

Relative vapor density : 1.9 (Air = 1.0)

Evaporation rate : No data available

Percent volatile : > 99 %

SECTION 10: Stability and reactivity

Reactivity : Stable under recommended storage conditions.

Chemical stability : This material is considered stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

Possibility of hazardous reactions SDS Number:100000014664 8/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

Hazardous reactions : Hazardous reactions: Hazardous polymerization may occur., See 'Conditions to Avoid' and/or “Materials to Avoid” in this section.

Further information: No decomposition if stored and applied as directed.

Hazardous reactions: Vapors may form explosive mixture with air.

Conditions to avoid : Heat, flames and sparks. Hazardous decomposition : Carbon oxides products

Other data : No decomposition if stored and applied as directed.

SECTION 11: Toxicological information

Crude Butadiene Acute oral toxicity : LD50 Oral: unknown Negligible or unlikely exposure pathways

Crude Butadiene Acute inhalation toxicity : LC50: > 50000 ppm Species: Rat Test atmosphere: gas Information given is based on data obtained from similar substances. Exposure to very high levels may trigger heartbeat irregularities (cardiac arrhythmia), and possible cardiac sensitization.

Crude Butadiene Acute dermal toxicity : LD50 Dermal: > 5,000 mg/kg Species: Rabbit Method: Acute toxicity estimate Negligible or unlikely exposure pathways

Crude Butadiene Skin irritation : May cause skin irritation in susceptible persons. Contact with liquid or refrigerated gas can cause cold burns and frostbite.

Crude Butadiene Eye irritation : Contact with eyes may cause irritation. Contact with liquid or refrigerated gas can cause cold burns and frostbite.

Crude Butadiene Sensitization : Did not cause sensitization on laboratory animals. Information refers to the main ingredient.

Crude Butadiene Repeated dose toxicity : This information is not available.

Genotoxicity in vitro SDS Number:100000014664 9/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

1,3-Butadiene : Test Type: Ames test Metabolic activation: with and without metabolic activation Result: Positive results were obtained in some in vitro tests.

Test Type: Chromosome aberration test in vitro Test system: Chinese hamster cells Method: OECD Guideline 473 Result: positive

n-Butane Test Type: Ames test Result: negative

Isobutane Test Type: Ames test Result: negative

Isobutylene Test Type: Ames test Result: negative

Test Type: Reverse mutation assay Result: negative

Test Type: Mouse lymphoma assay Result: negative

Test Type: Micronucleus test Result: negative

1-Butene Test Type: Ames test Metabolic activation: with and without metabolic activation Result: negative

cis-2-Butene Test Type: Reverse mutation assay Metabolic activation: with and without metabolic activation Result: negative

Test Type: Cell transformation assay Metabolic activation: with and without metabolic activation Result: negative

Test Type: in vitro test Result: negative

Isopentane Test Type: Ames test Concentration: 1, 2, 5, 8, 10% Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471 Result: negative

SDS Number:100000014664 10/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

Test Type: Ames test Concentration: 1, 2, 5, 8, 10, 25, 50% Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471 Result: negative Remarks: Information given is based on data obtained from similar substances.

Test Type: Chromosome aberration test in vitro Metabolic activation: with and without metabolic activation Method: Mutagenicity (in vitro mammalian cytogenetic test) Result: negative Remarks: Information given is based on data obtained from similar substances.

n-Pentane Test Type: Ames test Metabolic activation: with and without metabolic activation Result: negative

Test Type: Chromosome aberration test in vitro Metabolic activation: with and without metabolic activation Result: Ambiguous

Isoprene Test Type: Ames test Result: negative

Test Type: Sister Chromatid Exchange Assay Result: positive

Cyclopentane Test Type: Modified Ames test Concentration: 1250 microgram/plate Metabolic activation: with and without metabolic activation Method: see user defined free text Result: negative Remarks: In vitro tests did not show mutagenic effects

Test Type: Mouse lymphoma assay Concentration: 200 microgram/mililiter Metabolic activation: with and without metabolic activation Result: negative Remarks: In vitro tests did not show mutagenic effects

2-methyl-2-butene Test Type: Ames test Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471 Result: negative

Method: OECD Test Guideline 480 Result: negative

Benzene Test Type: Ames test Result: negative

SDS Number:100000014664 11/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

Test Type: Cytogenetic assay Result: positive

Test Type: Mouse lymphoma assay Result: positive

Test Type: Sister Chromatid Exchange Assay Result: negative

Genotoxicity in vivo 1,3-Butadiene : Test Type: Mouse micronucleus assay Species: mice Route of Application: inhalation (gas) Exposure time: 6 h per day for 5 days Dose: 50, 200, 500, 1300 ppm Method: OECD Test Guideline 474 Result: positive

Test Type: Dominant lethal assay Species: mice Method: OECD Test Guideline 478 Result: Positive results were obtained in some in vivo tests.

Isobutylene Test Type: Mouse micronucleus assay Result: negative

1-Butene Test Type: Micronucleus test Species: Mouse Dose: 1000, 3260, 10000 ppm Method: Mutagenicity (micronucleus test) Result: negative

cis-2-Butene Test Type: Mouse micronucleus assay Cell type: Bone marrow Dose: 10,000 ppm Result: negative

Test Type: Mouse micronucleus assay Cell type: Bone marrow Dose: 22, 000 ppm Result: negative

Isopentane Test Type: In vivo micronucleus test Species: Rat Cell type: Bone marrow Route of Application: inhalation (vapor) Method: Directive 67/548/EEC, Annex V, B.12. Remarks: Information given is based on data obtained from similar substances.

n-Pentane Test Type: Micronucleus test Species: Rat Cell type: Bone marrow Result: negative

Isoprene Result: negative

SDS Number:100000014664 12/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

Test Type: Micronucleus test Result: positive

Cyclopentane Test Type: Micronucleus test Species: Mouse Dose: 28.7 mg/l Result: negative

2-methyl-2-butene Test Type: Mouse micronucleus assay Species: Rat Cell type: Bone marrow Route of Application: Inhalation Exposure time: 6 h/d 2d Method: OECD Test Guideline 474 Result: positive

Benzene Test Type: Mouse micronucleus assay Result: positive

Carcinogenicity 1,3-Butadiene : Species: Mouse Sex: male and female Dose: 6.25, 20, 62.5, 200, 625 ppm Exposure time: 6hr/day. 5day/wk for up to 2 y Test substance: yes Print Date: OECD Test Guideline 453 Remarks: Clear evidence of multiple organ carcinogenicity.

Species: Rat Sex: male and female Dose: 1000, 8000 ppm Exposure time: 6 hr/day, 5 day/wk for 2 years Test substance: yes Remarks: weak oncogen

Isobutylene Species: Rat Sex: male Dose: 500, 2000, 8000 ppm Exposure time: 105 wks Number of exposures: 6 hrs/d, 5 d/wk Remarks: increased incidence of thyroid tumors

SDS Number:100000014664 13/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

Species: Rat Sex: female Dose: 500, 2000, 8000 ppm Exposure time: 105 wks Number of exposures: 6 hrs/d, 5 d/wk Remarks: no increase incidence of tumors

Species: Mouse Sex: male Dose: 500, 2000, 8000 ppm Exposure time: 105 wks Number of exposures: 6 hrs/d, 5 d/wk Remarks: no increase incidence of tumors

Species: Mouse Sex: female Dose: 500, 2000, 8000 ppm Exposure time: 105 wks Number of exposures: 6 hrs/d, 5 d/wk Remarks: no increase incidence of tumors

1-Butene Species: Rat Sex: male Dose: 0, 500, 2000, 8000 ppm Exposure time: 2 years Number of exposures: 6 hr/d, 5 d/wk Remarks: increased incidence of thyroid tumors, Information given is based on data obtained from similar substances.

Species: Rat Sex: female Dose: 0, 500, 2000, 8000 ppm Exposure time: 2 years Number of exposures: 6 hr/d, 5 d/wk Remarks: no increase incidence of tumors, Information given is based on data obtained from similar substances.

Species: Mouse Sex: male Dose: 0, 500, 2000, 8000 ppm Exposure time: 2 years Number of exposures: 6 hr/d, 5 d/wk Remarks: no increase incidence of tumors, Information given is based on data obtained from similar substances.

Species: Mouse Sex: female Dose: 0, 500, 2000, 8000 ppm Exposure time: 2 years Number of exposures: 6 hr/d, 5 d/wk Remarks: no increase incidence of tumors, Information given is based on data obtained from similar substances.

cis-2-Butene Species: Rat Dose: up to 8000 ppm Exposure time: 105 weeks Remarks: increased incidence of thyroid tumors

Isoprene Species: Rat Dose: 0. 70, 220, 700, 220, 7000 ppm SDS Number:100000014664 14/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

Exposure time: 26 wks Number of exposures: 6 h/d, 5 d/wk Remarks: interstitial cell hyperplasia of testis at 7000 ppm

Species: Mouse Dose: 0. 70, 220, 700, 220, 7000 ppm Exposure time: 26 wks Number of exposures: 6 h/d, 5 d/wk Remarks: malignant neoplastic lesions in the liver, lung, fore stomach and Harderian gland at 700 ppm

Benzene Species: Rat Sex: female Dose: 0, 25, 50, 250 mg/kg Exposure time: 103 wks Number of exposures: daily, 5 days/week Test substance: yes Remarks: zymbal gland carcinomas, squamous cell papillomas

Species: Rat Sex: male Dose: 0, 50, 100, 200 mg/kg Exposure time: 103 wks Number of exposures: daily, 5 days/week Test substance: yes Remarks: zymbal gland carcinomas, squamous cell papillomas

Species: Mouse Sex: male and female Dose: 25, 50, 100 mg/kg Exposure time: 103 wks Number of exposures: daily, 5 days/week Test substance: yes Remarks: Clear evidence of multiple organ carcinogenicity.

Crude Butadiene Reproductive toxicity : This information is not available.

Crude Butadiene Developmental Toxicity : This information is not available.

Crude Butadiene Aspiration toxicity : No aspiration toxicity classification. Toxicology Assessment

Crude Butadiene CMR effects : Carcinogenicity: Not available Mutagenicity: In vivo tests showed mutagenic effects Teratogenicity: Not available Reproductive toxicity:

SDS Number:100000014664 15/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

Not available

Crude Butadiene Further information : Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomiting. Concentrations substantially above the TLV value may cause narcotic effects. Solvents may degrease the skin.

SECTION 12: Ecological information

Ecotoxicity effects

Toxicity to fish : No data available

Toxicity to daphnia and : No data available other aquatic invertebrates

Toxicity to algae : No data available

Biodegradability : This material is volatile and is expected to partition to air. Expected to be biodegradable

Elimination information (persistence and degradability)

Bioaccumulation : Bioaccumulation is unlikely.

Mobility

n-Butane : The product evaporates readily.

1-Butene : Medium: Air Method: Calculation, Mackay Level I Fugacity Model

: Medium: Water Method: Calculation, Mackay Level I Fugacity Model

n-Pentane : After release, disperses into the air.

Benzene : No data available

Results of PBT assessment : This mixture contains no substance considered to be persistent, bioaccumulating and toxic (PBT).

Additional ecological : An environmental hazard cannot be excluded in the event of information unprofessional handling or disposal., Harmful to aquatic life with long lasting effects.

Ecotoxicology Assessment

Short-term (acute) aquatic hazard 1-Butene : This material is not expected to be harmful to aquatic organisms. SDS Number:100000014664 16/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

Isopentane : Toxic to aquatic life.

n-Pentane : Toxic to aquatic life.

Isoprene : Toxic to aquatic life.

Cyclopentane : Harmful to aquatic life.

2-methyl-2-butene : Toxic to aquatic life.

Benzene : Toxic to aquatic life.

Long-term (chronic) aquatic hazard 1-Butene : This material is not expected to be harmful to aquatic organisms.

Isopentane : This material is not expected to be harmful to aquatic organisms.

n-Pentane : Toxic to aquatic life with long lasting effects.

Isoprene : Toxic to aquatic life with long lasting effects.

Cyclopentane : Harmful to aquatic life with long lasting effects.

2-methyl-2-butene : Toxic to aquatic life with long lasting effects.

Benzene : Harmful to aquatic life with long lasting effects.

SECTION 13: Disposal considerations

The information in this SDS pertains only to the product as shipped. Use material for its intended purpose or recycle if possible. This material, if it must be discarded, may meet the criteria of a hazardous waste as defined by US EPA under RCRA (40 CFR 261) or other State and local regulations. Measurement of certain physical properties and analysis for regulated components may be necessary to make a correct determination. If this material is classified as a hazardous waste, federal law requires disposal at a licensed hazardous waste disposal facility.

Product : The product should not be allowed to enter drains, water courses or the soil. Do not contaminate ponds, waterways or ditches with chemical or used container. Send to a licensed waste management company.

Contaminated packaging : Empty remaining contents. Dispose of as unused product. Do not re-use empty containers. Do not burn, or use a cutting torch on, the empty drum.

SECTION 14: Transport information The shipping descriptions shown here are for bulk shipments only, and may not apply to shipments in non-bulk packages (see regulatory definition).

Consult the appropriate domestic or international mode-specific and quantity-specific Dangerous Goods Regulations for additional shipping description requirements (e.g., technical name or names, etc.) Therefore, the information shown here, may not always agree with the bill of lading shipping SDS Number:100000014664 17/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

description for the material. Flashpoints for the material may vary slightly between the SDS and the bill of lading.

US DOT (UNITED STATES DEPARTMENT OF TRANSPORTATION) UN1010, BUTADIENES AND HYDROCARBON MIXTURE, STABILIZED, 2.1, RQ (1,3- BUTADIENE, BENZENE)

IMO / IMDG (INTERNATIONAL MARITIME DANGEROUS GOODS) UN1010, BUTADIENES AND HYDROCARBON MIXTURE, STABILIZED, 2.1, (-76°C)

IATA (INTERNATIONAL AIR TRANSPORT ASSOCIATION) UN1010, BUTADIENES AND HYDROCARBON MIXTURE, STABILIZED, 2.1

ADR (AGREEMENT ON DANGEROUS GOODS BY ROAD (EUROPE)) UN1010, BUTADIENES AND HYDROCARBON MIXTURE, STABILIZED, 2.1, (B/D)

RID (REGULATIONS CONCERNING THE INTERNATIONAL TRANSPORT OF DANGEROUS GOODS (EUROPE)) UN1010, BUTADIENES AND HYDROCARBON MIXTURE, STABILIZED, 2.1

ADN (EUROPEAN AGREEMENT CONCERNING THE INTERNATIONAL CARRIAGE OF DANGEROUS GOODS BY INLAND WATERWAYS) UN1010, BUTADIENES AND HYDROCARBON MIXTURE, STABILIZED, 2.1

Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

Other information : IGC CODE: MIXED C4 CARGOES, S.T. 2G/2PG

SECTION 15: Regulatory information

National legislation

SARA 311/312 Hazards : Flammable (gases, aerosols, liquids, or solids) Gases under pressure Acute toxicity (any route of exposure) Skin corrosion or irritation Serious eye damage or eye irritation Germ cell mutagenicity Carcinogenicity Specific target organ toxicity (single or repeated exposure)

CERCLA Reportable : 13 lbs Quantity 1,3-Butadiene

SDS Number:100000014664 18/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

SARA 302 Reportable : This material does not contain any components with a SARA Quantity 302 RQ.

SARA 302 Threshold : No chemicals in this material are subject to the reporting Planning Quantity requirements of SARA Title III, Section 302.

SARA 304 Reportable : This material does not contain any components with a section Quantity 304 EHS RQ.

SARA 313 Components : The following components are subject to reporting levels established by SARA Title III, Section 313:

: 1,3-Butadiene - 106-99-0 Benzene - 71-43-2 Isoprene - 78-79-5

Clean Air Act

Ozone-Depletion : This product neither contains, nor was manufactured with a Class I or Potential Class II ODS as defined by the U.S. Clean Air Act Section 602 (40 CFR 82, Subpt. A, App.A + B).

The following chemical(s) are listed as HAP under the U.S. Clean Air Act, Section 112 (40 CFR 61): : 1,3-Butadiene - 106-99-0 Benzene - 71-43-2

The following chemical(s) are listed under the U.S. Clean Air Act Section 112(r) for Accidental Release Prevention (40 CFR 68.130, Subpart F): : 1,3-Butadiene - 106-99-0 n-Butane - 106-97-8 Isobutane - 75-28-5 Isobutylene - 115-11-7 1-Butene - 106-98-9 cis-2-Butene - 590-18-1 trans-2-Butene - 624-64-6 1,3-Pentadiene - 504-60-9 Isopentane - 78-78-4 n-Pentane - 109-66-0 Isoprene - 78-79-5 cis-2-Pentene - 627-20-3 trans-2-Pentene - 646-04-8 3-Methyl-1-Butene - 563-45-1 2-methyl-1-butene - 563-46-2

The following chemical(s) are listed under the U.S. Clean Air Act Section 111 SOCMI Intermediate or Final VOC's (40 CFR 60.489): SDS Number:100000014664 19/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

: 1,3-Butadiene - 106-99-0 Isobutylene - 115-11-7 1-Butene - 106-98-9 Isopentane - 78-78-4 n-Pentane - 109-66-0 Isoprene - 78-79-5 Benzene - 71-43-2

US State Regulations

Pennsylvania Right To Know : 1,3-Butadiene - 106-99-0 n-Butane - 106-97-8 Isobutylene - 115-11-7 1-Butene - 106-98-9 cis-2-Butene - 590-18-1 trans-2-Butene - 624-64-6 Isopentane - 78-78-4 n-Pentane - 109-66-0 Cyclopentadiene - 542-92-7 Isoprene - 78-79-5 Cyclopentane - 287-92-3 2-methyl-2-butene - 513-35-9 Benzene - 71-43-2 Isobutane - 75-28-5

California Prop. 65 : WARNING: This product can expose you to chemicals including Components [listed below], which is [are] known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov/food.

1,3-Butadiene 106-99-0

WARNING: This product can expose you to chemicals including [listed below], which is [are] known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

1,3-Butadiene 106-99-0

Notification status Europe REACH : Not in compliance with the inventory Switzerland CH INV : On the inventory, or in compliance with the inventory United States of America (USA) : On or in compliance with the active portion of the TSCA TSCA inventory Australia AICS : On the inventory, or in compliance with the inventory

SDS Number:100000014664 20/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

New Zealand NZIoC : Not in compliance with the inventory Japan ENCS : Not in compliance with the inventory Korea KECI : A substance(s) in this product was not registered, notified to be registered, or exempted from registration by CPChem according to K-REACH regulations. Importation or manufacture of this product is still permitted provided the Korean Importer of Record has themselves notified the substance or the exported amount does not exceed the minimum threshold quantity of the non-registered substance(s).

Philippines PICCS : Not in compliance with the inventory China IECSC : Not in compliance with the inventory Taiwan TCSI : Not in compliance with the inventory

SECTION 16: Other information

NFPA Classification : Health Hazard: 2 Fire Hazard: 4 Reactivity Hazard: 2 4

2 2

Further information Legacy SDS Number : 1773

Significant changes since the last version are highlighted in the margin. This version replaces all previous versions.

The information in this SDS pertains only to the product as shipped. The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text.

Key or legend to abbreviations and acronyms used in the safety data sheet ACGIH American Conference of LD50 Lethal Dose 50% Government Industrial Hygienists AICS Australia, Inventory of Chemical LOAEL Lowest Observed Adverse Effect Substances Level DSL Canada, Domestic Substances NFPA National Fire Protection Agency List NDSL Canada, Non-Domestic NIOSH National Institute for Occupational Substances List Safety & Health CNS Central Nervous System NTP National Toxicology Program CAS Chemical Abstract Service NZloC New Zealand Inventory of Chemicals EC50 Effective Concentration NOAEL No Observable Adverse Effect Level EC50 Effective Concentration 50% NOEC No Observed Effect Concentration EGEST EOSCA Generic Exposure OSHA Occupational Safety & Health Scenario Tool Administration SDS Number:100000014664 21/22

SAFETY DATA SHEET Crude Butadiene Version 4.0 Revision Date 2021-03-30

EOSCA European Oilfield Specialty PEL Permissible Exposure Limit Chemicals Association EINECS European Inventory of Existing PICCS Philippines Inventory of Chemical Substances Commercial Chemical Substances MAK Germany Maximum Concentration PRNT Presumed Not Toxic Values GHS Globally Harmonized System RCRA Resource Conservation Recovery Act >= Greater Than or Equal To STEL Short-term Exposure Limit IC50 Inhibition Concentration 50% SARA Superfund Amendments and Reauthorization Act. IARC International Agency for Research TLV Threshold Limit Value on Cancer IECSC Inventory of Existing Chemical TWA Time Weighted Average Substances in China ENCS Japan, Inventory of Existing and TSCA Toxic Substance Control Act New Chemical Substances KECI Korea, Existing Chemical UVCB Unknown or Variable Composition, Inventory Complex Reaction Products, and Biological Materials <= Less Than or Equal To WHMIS Workplace Hazardous Materials Information System LC50 Lethal Concentration 50%

SDS Number:100000014664 22/22