Topical Ocular Therapeutic Pharmaceutical Agents Available in Canada 2013
Antibiotic Agents: (brand names in italics)
Besivance – besifloxacin 0.6% suspension Ciloxan – ciprofloxacin 0.3% solution and ointment Erythromycin – erythromycin 0.5% ointment Gentamycin– gentamicin sulphate 0.3% solution and ointment Neosporin – polymyxin B, neomycin and gramicidin/bacitracin solution and ointment Ocuflox – ofloxacin 0.3% solution Polysporin – polymyxin B 10,000IU and gramicidin 0.025mg/bacitracin 500IU solution and ointment Polytrim – trimethoprim 0.1% and polymixin B solution Tobrex – tobramycin 0.3% ointment Tobramycin – tobramycin 0.3% solution Vigamox – moxifloxacin 0.5% solution Zymar – gatifloxacin 0.3% solution
AzaSite (azithromycin 1% solution) is not available in Canada. Bacitracin ointment is not available in Canada. Iquix is not available in Canada. Quixin is not available in Canada. Sulfacetamide (Sodium Sulamyd/Cetamide) has been discontinued for sale in Canada.
Anti-Viral and NSAID Agents: (brand names in italics)
Nevanac – nepanfenac 0.1% suspension (NSAID) Viroptic – triflurine 1% solution (Anti-Viral) Voltaren – diclofenac sodium 0.1% solution (NSAID)
Corticosteroid Agents: (brand names in italics)
Alrex – loteprednol etabonate 0.2% suspension (good for allergic conjunctivitis) Decadron – dexamethasone 0.1% solution (rarely used in clinical care) Flarex – fluorometholone acetate 0.1% suspension (good for acute inflammation) FML – fluorometholone alcohol 0.1% suspension (good for chronic inflammation) Pred Forte – prednisolone acetate 1% suspension (good for severe inflammation) Pred Mild – prednisolone acetate .12% suspension Lotemax – loteprednol etabonate 0.5% suspension (good for dry-eye patients) Maxidex – dexamethasone 0.1% suspension and ointment (rarely used in clinical care) Vexol – rimexolone 1% suspension
Eflone (Novartis) is not available in Canada but is identical to Flarex (Alcon.) Inflamase Forte (prednisolone sodium phosphate 1% solution) has been discontinued for sale in Canada.
Corticosteroid/Antibiotic Combination Agents: (brand names in italics)
Blephamide – prednisolone acetate 0.2% (steroid) with sodium sulfacetamide 10% (antibiotic) suspension and ointment Cortisporin – hydrocortisone 1% (steroid) with neomycin 0.35% and polymyxin B 10,000u/ml (antibiotics) suspension Maxitrol – hydrocortisone 1% (steroid) with neomycin 0.35% and polymyxin B 10,000u/ml (antibiotics) suspension Pentasone – betamethasone 0.1% (steroid) with gentamicin 0.3% (antibiotic) suspension and ointment Opticort – dexamethasone 0.5mg (steroid) with framycetin 5mg and gramicidin 50mcg (antibiotics) solution TobraDex – dexamethasone 0.1% (steroid) with tobramycin 0.3% (antibiotic) suspension and ointment
Dexacidin is not available in Canada. FML-S is not available in Canada. Garasone is not available in Canada. It has been discontinued. Isopto-Cetapred is not available in Canada. NeoDecadron is not available in Canada. Poly-Pred is not available in Canada. Pred-G is not available in Canada. Vasocidin is not available in Canada. It was discontinued.
Zylet (loteprednol 0.5% and tobramycin 0.3%) is not available in Canada but is commonly used in the US.
Anti-Allergy Agents: (brand names in italics)
Acular – ketorolac tromethamine 0.5% solution (not available as preservative free) Acular LS – ketorolac tromethamine 0.4% solution (not available as preservative free) Alocril – nedocromil sodium 2% solution (chronic care product) Alrex – loteprednol etabonate 0.2% suspension Alomide – lodoxamide tromethamine 0.1% solution (chronic care product) Opticrom – cromolyn sodium 4% solution (chronic care product) Pataday – olopatadine hydrochloride 0.2% solution Patanol – olopatadine hydrochloride 0.1% solution Zaditor – ketotifen fumarate 0.025% solution
Alamast is not available in Canada. Alaway is not available in Canada. Crolom is not available in Canada. Elestat is not available in Canada. Emadine is not available in Canada. Optivar is not available in Canada.
Dry Eye Agents: (brand names in italics)
Restasis – cyclosporine ophthalmic emulsion 0.05% (Ontario ODs cannot prescribe this medication.)
Anti-Glaucoma Agents: (brand names in italics)
Beta Blockers: Betagan – levobulolol hydrochloride 0.25% and 0.5% solution Betoptic – betaxolol hydrochloride 0.25% solution (discontinued due to stinging) Betoptic S – betaxolol hydrochloride 0.25% suspension Timoptic – timolol maleate 0.25% and 0.5% solution Timoptic XE – timolol maleate 0.25% and 0.5% gel-based vehicle
Prostaglandin Analogs: Lumigan – bimatoprost 0.01% and 0.03% solution Travatan – travoprost 0.004% solution Travatan Z – travoprost 0.004% solution without BAK (good for dry-eye patients) Xalatan – latanoprost 0.005% solution
Alpha Agonists: Alphagan P – brimonidine 0.15% solution Apo-brimonidine – brimonidine 0.2% solution Iopidine – apraclonidine 0.5% and 1% solution
Carbonic Anhydrase Inhibitors: Azopt – brinzolamide 1% suspension Trusopt – dorzolamide 2% solution
Combination Anti-Glaucoma Medications: Azarga – brimzolamide 1.0% with timolol 0.5% suspension (Ontario ODs cannot prescribe this medication.) Combigan – brimonidine 0.2% with timolol 0.5% solution Cosopt – dorzolamide 2% with timolol 0.5% solution DuoTrav – travoprost 0.004% with timolol 0.5% solution Xalacom – latanoprost 50mcg with timolol 0.5% solution
Other Anti-Glaucoma Agents: Carbochol – carbochol 1.5% and 3% solution Pilocarpine – pilocarpine 1% 2%, 4%, and 6% solution Pilopine HS – pilocarpine 4% gel-based vehicle
Betimol is not available in Canada. Istalol is not available in Canada. Lopidine is not available in Canada.
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