Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000279715Cyc: Streptococcus pneumoniae GA54354 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari spermidine D-mannitol putrescine uracil

predicted PEP-driven RS09560 RS09150 transporter of D-mannitol

spermidine uracil putrescine D-mannitol 1-phosphate

Macromolecule Modification , Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis Secondary Metabolite queuosine biosynthesis α 5'-deoxy-5'- 4-hydroxy-2- a negatively D-sedoheptulose DNA combined D-ribulose Fatty Acid and Lipid Biosynthesis Degradation a glutaryl-[acp] a (4Z)-hexadec- -D- DHAP [2Fe-2S] iron-sulfur cluster biosynthesis Polymeric Compound Degradation a (6S)-5-formyltetrahydrofolate glu a malonyl-[acp] a purine a malonyl-[acp] 1-phosphate with exogenous thiamine formation from pyrithiamine and oxythiamine (yeast) N 10 -formyl-tetrahydrofolate biosynthesis tetrahydrofolate biosynthesis methyl ester arsenate 4-enoyl-[acp] glucopyranose ATP fluoroadenosine oxoglutarate supercoiled DNA 5-phosphate flavin biosynthesis I (bacteria and plants) thiamine diphosphate lipoate salvage II mannitol ribonucleoside purine-nucleoside fructose- penicillin- beta-ketoacyl- beta-ketoacyl- bifunctional 2-keto- DNA DNA to form a ribulose- biosynthesis III palmitate biosynthesis II (bacteria and plants) preQ bifunctional purine-nucleoside 1-phosphate 0 degradation I phosphorylase: topoisomerase IV: bisphosphate binding protein: phosphate 3- (7,8-dihydropterin- a [lipoyl-carrier acyl-[acyl-carrier protein] glycogen degradation II [acyl-carrier- [acyl-carrier- glucose-1-phosphate 4-hydroxyglutarate recombinationalHolliday junction L-cysteine desulfurase (Staphylococcus) pyrithiamine phosphatidylglycerol chitin degradation II (Vibrio) folylpolyglutamate phosphorylase: a tetrahydrofolate 6 pathway adenylyltransferase: CN62_RS07150 aldolase/2- CN62_RS07250 aldolase: junction CN62_RS13160 epimerase: 2-(2-carboxy-4- 6-yl)methyl 4-aminobenzoate protein]-N - biosynthesis II D-mannitol synthase/dihydrofolate protein] protein] resolvase RuvX: GTP CN62_RS07150 CN62_RS04660 diphosphate dihydropteroate lipoyl-L-lysine 1-phosphate synthase II: synthase II: CN62_RS08445 purine-nucleoside keto-3-deoxy-6- CN62_RS07260 glycerol-3- CN62_RS12385 cysteine HMP-PP methylthiazol-5- thiaminase II: an acetoacetyl-[acp] (non-plastidic) a glycogen synthase: CN62_RS04375 CN62_RS04365 an acyl-[acyl- preQ chitin mannitol-1- purine-nucleoside phosphorylase: phosphogluconate phosphate desulfurase: yl)ethylthiamine phosphate synthase: 1 CN62_RS05410 CN62_RS05410 glucose-1-phosphate type I DNA fructose- ribulose- bifunctional CN62_RS06590 DHAP carrier protein] phosphate 5- bifunctional phosphorylase: Holliday junction CN62_RS04835 hypothetical glycogen/ adenylyltransferase CN62_RS07170 aldolase: topoisomerase: bisphosphate dehydrogenase phosphate 3- CN62_RS07345 phosphate 7,8- (R)-lipoate acyl-ACP tRNA folylpolyglutamate 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- resolution ofresolvase RecU: 3,4-dihydroxy- 4-amino-2-methyl-5- glycerol-3- dehydrogenase: CN62_RS07170 5-fluoro-5- CN62_RS04920 (NAD(P)(+)): synthase: protein: thioesterase: starch/alpha- subunit GlgD: CN62_RS09045 aldolase: epimerase: [+ 3 isozymes] 2-butanone- dihydropteroate phosphate guanosine(34) CN62_RS05295 synthase/dihydrofolate carrier-protein] carrier-protein] recombinationalCN62_RS05150 pyrimidinemethanol lipoate-- CN62_RS03855 glucan family ribose-1-arsenate a purine base CN62_RS08450 deoxy-D-ribose adenine CN62_RS06115 CN62_RS13115 CN62_RS10565 CN62_RS06570 CN62_RS09655 transglycosylase synthase: CN62_RS04840 reductase: reductase: pyruvate glyoxylate a relaxed DNA junction an S-sulfanyl-[L- 4-phosphate bifunctional dehydrogenase F6P ADP-α-D-glucose 1-phosphate D-xylulose bifunctional protein : [+ 2 isozymes] a fatty acid phosphorylase: a chitodextrin D-erythrose DHAP sn-glycerol synthase/GTP thiamine folylpolyglutamate (NAD(P)(+)): Tgt: a (6S)-5-formyltetrahydrofolate CN62_RS05405 CN62_RS05405a (6Z)-3- formation of two cysteine desulfurase] hydroxymethylpyrimidine CN62_RS14575 a (3R)-3- CN62_RS13195 a 3-oxopimeloyl- 3-phosphate 5-phosphate cyclohydrolase II: phosphate synthase/ CN62_RS13115 CN62_RS12805 acyl-carrier protein acyl-carrier protein oxooctadec- intact strands kinase/ dihydrofolate hydroxybutanoyl- [acp] methyl ester CN62_RS04200 synthase: dihydrofolate (lipoyl)adenylate a 7-aminomethyl-7- an α-limit dextrin 6-enoyl-[acp] phosphomethylpyrimidine reductase: [acp] penicillin- 34 2,5-diamino-6- CN62_RS06605 synthase: deazaguanosine thiamine kinase: CN62_RS06610 CN62_RS10365 (3R)-3- binding protein: 4-alpha- an S-sulfanyl-[cysteine (5-phospho-D- CN62_RS04375 lipoate-- in tRNA a chitodextrin phosphate hydroxybutanoyl- CN62_RS13160 a glycopeptide- 2251 ribosylamino) hydroxymethylpyrimidine/ protein ligase: tRNA preQ1(34) S- glucanotransferase: a malonyl-[acp] 5'-chloro-5'- (4S)-4-hydroxy- guanosine desulfurase]-[disordered- serine sn-glycerol 4 glycerophosphoserine KDGP 3-ethylmalate acetyl-CoA a 7,8-dihydrofolate a 5-methyltetrahydrofolate bifunctional [acyl-carrier CN62_RS13200 D-mannosyl-N a malonyl-[acp] a purine deoxyadenosine 2-oxoglutarate in 23S rRNA form scaffold pyrimidin- phosphomethylpyrimidine CN62_RS14575 3-phosphate adenosylmethionine methyl ester biotin ATP formate ATP hydroxymethyltransferase: glyA folylpolyglutamate protein] -(N-acetyl-D- glycerophosphodiester ribonucleoside purine-nucleoside bifunctional 2-keto- 23S rRNA 3-isopropylmalate acetyl-CoA 4(3H)-one kinase: CN62_RS10480 a [glycine- ribosyltransferase- a debranched beta-ketoacyl- bifunctional 2-keto- protein] complex oxythiamine purine-nucleoside phosphorylase: dehydrogenase: anaerobic [cysteine desulfurase]-S- synthase/ cleavage complex dehydratase: glycerol-3- α-limit dextrin glucosaminyl) [acyl-carrier- : 4-hydroxyglutarate 4-hydroxyglutarate (guanosine(2251) bifunctional biotin- carboxylase bifunctional thymidylate S-adenosyl-L-methionine cycle I QueA: endo-beta-N- phosphorylase: ribonucleoside- HMP-P dihydrofolate 6 CN62_RS05420 phosphate -asparagine CN62_RS07895 CN62_RS07150 aldolase/2- -2'-O)- -[acetyl-CoA- CN62_RS08990 biotin carboxyl sulfanylcysteine:[acceptor diaminohydroxyphosphoribosylaminopyrimidine thiamine H protein] N - CN62_RS09695 2 protein] aldolase/2- thiaminase II: synthase: beta-N- acetylglucosaminidase: CN62_RS07150 triphosphate protein]-cysteine synthase: acyltransferase: glycogen/ synthase II: glycerophosphodiester keto-3-deoxy-6- purine-nucleoside keto-3-deoxy-6- methyltransferase carboxylase] 3-isopropylmalate carrier protein: deaminase/5-amino-6-(5-phosphoribosylamino) CN62_RS06385 lipoyl-L-lysine a (2E)-but- 34 acetylhexosaminidase: CN62_RS05685 reductase: thiamine CN62_RS06590 bifunctional CN62_RS04840 CN62_RS07245 an epoxyqueuosine purine-nucleoside phosphogluconate RlmB: synthetase/ CN62_RS05415 sulfurtransferase: uracil reductase RibD: CN62_RS04210 SAM starch/alpha- CN62_RS05410 phosphodiesterase: phosphogluconate phosphorylase: dehydrogenase: hydroxymethylpyrimidine hypothetical 2-enoyl-[acp] a 1-acyl-sn in tRNA CN62_RS03670 endo-beta-N- CN62_RS04400 CN62_RS07405 5-amino-6-(5- diphosphokinase: 5-(2-hydroxyethyl) glucan family CN62_RS12140 aldolase: phosphorylase: CN62_RS07170 aldolase: CN62_RS09825 biotin operon CN62_RS09020 [+ 3 isozymes] 7,8-dihydrofolate 3-oxoacyl-[acyl- 2-O- a [cysteine desulfurase]- CN62_RS12380 kinase/ protein: bifunctional a (6S)-5- crotonyl-[acyl- -glycerol 3- D-glucopyranose beta-N- acetylglucosaminidase: CN62_RS07170 5-chloro-5- CN62_RS04920 repressor: dATP phospho-D- -4-methylthiazole monoglutamate phosphorylase: a glycopeptide- sn-glycerol CN62_RS04920 2251 2-oxovalerate malonyl-CoA phosphomethylpyrimidine CN62_RS13955 a [lipoyl-carrier phosphate acetylhexosaminidase: N-acetyl-D-CN62_RS07770 carrier-protein] ser α-D-ribose- methylguanosine S-sulfanyl-[disordered- D-ribulose ribosylamino)uracil methylenetetrahydrofolate formyltetrahydrofolate S-adenosylmethionine carrier-protein] CN62_RS13195 D-mannosyl- 3-phosphate D-glyceraldehyde a purine base adenine deoxyribose CN62_RS11865 thiamine hydroxyethylthiazole methylenetetrahydrofolate protein]-N 6 - reductase: pyruvate 1-phosphate pyruvate glyoxylate in 23S rRNA biotinyl-5'- form scaffold kinase: CN62_RS06610 dehydrogenase/ reductase: 1-acyl-sn-glycerol- CN62_RS13370 4 glucosamine- 5-phosphate bifunctional diphosphate 5-formyltetrahydrofolate synthase: 34 N,N'- N,N',N''- N -N-acetyl- 3-phosphate 1-phosphate kinase: CN62_RS06565 reductase [NAD(P) lipoyl-L-lysine 3-phosphate a queuosine asparagine CN62_RS05405 adenylate protein] complex diaminohydroxyphosphoribosylaminopyrimidine hydroxymethylpyrimidine/ methenyltetrahydrofolate cyclo-ligase: CN62_RS06835 CN62_RS05395 α-D- glucokinase: diacetylchitobiose triacetylchitotriose D-glucosamine cysteine bifunctional hydroxyethylthiazole H]: CN62_RS06045 acyltransferase: in tRNA a 3-oxoglutaryl- deaminase/5-amino-6-(5-phosphoribosylamino) phosphomethylpyrimidine cyclohydrolase: CN62_RS13140 glucopyranose CN62_RS06380 beta-N- acyl-carrier protein desulfurase: 3,4-dihydroxy- kinase: CN62_RS06600 a 7,8-dihydrofolate [acp] methyl ester kinase: CN62_RS10480 CN62_RS07125 met SAH a butanoyl-[acp] CN62_RS10600 1-phosphate met RS04125 met uracil reductase RibD: CN62_RS04210 4-methyl-5-(2- a 5,10- a 5,10- a 1,2-diacyl- acetylhexosaminidase: CN62_RS07345 2-butanone- 5-amino-6-(5- phosphooxyethyl) methylenetetrahydrofolate methenyltetrahydrofolate dihydrofolate 5'-methylthioadenosine/ sn-glycerol CN62_RS13370 [+ 3 isozymes] 4-phosphate HMP-PP beta-ketoacyl- an S-sulfanyl-[cysteine phospho-D- reductase: adenosylhomocysteine an inactive a 3,5,7,9,11,13,15- synthase/GTP thiamine salvage II thiazole bifunctional 3-phosphate lipoprotein posttranslational beta-N- an [apo BCAA (2R,3S)-3- a double ribitylamino)uracil [acyl-carrier- hyaluronan degradation glycerophosphoglycerol a uracil in DNA a [protein] Ser/Thr desulfurase]-S- CN62_RS10365 nucleosidase: modification acetylhexosaminidase: ribonucleoside a reduced a palmitoleoyl-[acp] a malonyl-[acp] (S)-3-methyl-2- dehydrogenase a purine 2'- hepta-oxo- isopropylmalate stranded DNA a protein cyclohydrolase II: methylenetetrahydrofolate 5-methyltetrahydropteroyltriglutamate- protein] SAM formate GTP sulfanyl-[disordered- 4-amino-2-methyl-5- thiamine CN62_RS07880 CN62_RS03670 triphosphate flavodoxin glycerophosphodiester oxopentanoate E2 protein] N 6 deoxyribonucleoside uracil-DNA hexadecanoyl-[PKS-acp]aldo/keto serine/threonine 3-isopropylmalate DNA gyrase CN62_RS04200 dehydrogenase/ a tetrahydrofolate - homocysteine S- synthase II: beta-ketoacyl- ATP-dependent form scaffold pyrimidinemethanol a [prolipoprotein]- hyaluronan reductase anaerobic phosphodiesterase: branched-chain purine-nucleoside glycosylase: protein kinase: dehydrogenase: subunit B: anaerobic 1-deoxy-L- phosphate methenyltetrahydrofolate methyltransferase: CN62_RS06040 N-acetyl-D- [acyl-carrier- -lipoyl-L-lysine reductase: Clp protease thiamine salvage IV (yeast) S-ribosyl-L- CN62_RS05410 a CDP- L-cysteine D-glucopyranose ribonucleoside- alpha-keto acid phosphorylase: ribonucleoside- protein] complex bifunctional synthase: L-homocysteine glucosamine hyaluronate : CN62_RS12140 CN62_RS06200 CN62_RS06980 CN62_RS11125 CN62_RS08990 CN62_RS07050 [cysteine desulfurase]-S- glycero-tetrulose L-cysteine biosynthesis cyclohydrolase: homocysteine 6-phosphate protein] proteolytic ARP thiamine salvage III 3-oxoacyl-[acyl- diacylglycerol prolipoprotein CN62_RS04915 triphosphate dehydrogenase CN62_RS07150 triphosphate 4-phosphate hydroxymethylpyrimidine CN62_RS06570 CN62_RS07125 synthase II: glycerophosphodiester uracil-DNA aldo/keto HPr kinase/ 3-isopropylmalate DNA gyrase subunit: sulfanylcysteine:[acceptor VI (from L-methionine) 3-(4-deoxy-β-D-gluc-4-enuronosyl) reductase subunit E2: reductase: kinase/ thiamine carrier-protein] CDP-diacylglycerol-- diacylglyceryl phosphodiesterase: purine-nucleoside glycosylase: phosphorylase: dehydrogenase: subunit A: protein]-cysteine thiamine an N 10 - CN62_RS05410 an [apo BCAA dehydrogenase reductase: CN62_RS06755 reductase: glycerol-3-phosphate 3- : -N-acetyl-D-glucosamine activating protein: CN62_RS08595 phosphorylase: CN62_RS04400 6,7-dimethyl-8- thiamine phosphomethylpyrimidine phosphate superpathway of heme CN62_RS07895 6 CN62_RS08625 CN62_RS09925 CN62_RS09680 CN62_RS09020 CN62_RS08835 sulfurtransferase: met formyltetrahydrofolate NAD de novo biosynthesis CN62_RS05405 CN62_RS09675 CN62_RS04415 an active 3-oxoacyl-[acyl- E2 protein] N -S-[2- an apyrimidinic 9-hydroxy-3,5,7,11,13,15- 4-methyl-2- a negatively a peptide ribityllumazine thiamine kinase: CN62_RS06610 S-ribosylhomocysteine phosphatidyltransferase: sn-glycerol 2-deoxy-α- CN62_RS07170 a [protein] (L-serine/L- dGTP CN62_RS07405 synthase: S-adenosylmethionine thiaminase II: b biosynthesis from a flavodoxin ribonucleoside carrier-protein] glycerol methylbutanoyl]dihydrolipoyl- uracil hexaoxohexadecanoyl- a [cysteine diphosphokinase: I (from aspartate) lyase: CN62_RS05025 CN62_RS13730 a [prolipoprotein]- met 5'-deoxyadenosine 3-phosphate site in DNA threonine) phosphate oxopentanoate supercoiled DNA synthase: hydroxymethylpyrimidine/ CN62_RS06605 CN62_RS06590 uroporphyrinogen-III a 3-oxohexanoyl- D-ribose 1- a purine base desulfurase]-(S- synthase: S-1,2-diacyl-sn- 4-deoxy-L-threo-hex- semiquinone triphosphate reductase: L-lysine [PKS-acp] CN62_RS04195 CN62_RS12380 S-ribosylhomocysteinase: [acp] 1-(3-sn- N-acetyl-D-glucosamine phosphate phosphomethylpyrimidine CN62_RS06835 4-enopyranuronate reductase CN62_RS05405 sulfanyl) -[disordered- thiamine asp uroporphyrinogen-III CN62_RS05040 phosphatidyl) glyceryl-L-cysteine an (11Z)-3- 2 kinase: CN62_RS10480 thiamine SAM 4-amino-2-methyl-5- hypothetical form scaffold diphosphate 5-(2-hydroxyethyl)-4-methylthiazole -sn-glycerol acyl-carrier protein oxooctadec- 6,7-dimethyl-8-(1- phosphate pyrimidinemethanol protein: signal peptidase protein] complex HMP-P 3-phosphate fatty acid elongation -- saturated 11-enoyl-[acp] D-ribityl)lumazine hydroxyethylthiazole CN62_RS03855 II: CN62_RS07640 bifunctional coproporphyrinogen III riboflavin kinase: CN62_RS06565 2-iminosuccinate superpathway of pyrimidine Nucleoside and Nucleotide Degradation bifunctional hydroxymethylpyrimidine heme b biosynthesis [+ 2 isozymes] an (S-diacyl- undecaprenyl- 1-palmitoyl- an [apo BCAA a 6-phospho- 3-[(4'- 1939 a (7Z)-3-oxo- a (5Z)-3- synthase: kinase/ hydroxyethylthiazole a (3R)-3- an acetoacetyl-[acp] a lipoprotein deoxyribonucleosides degradation maltotetraose 3-[(7'-methylsulfanyl) a uracil hydroxymethylpyrimidine II (anaerobic) an L-1- a [cysteine desulfurase]- CN62_RS04205 5-(2-hydroxyethyl) hydroxyhexanoyl- sn-glyceryl) signal peptide diphospho-N- a palmitoleoyl-[acp] sn-glycerol 4-methyl-2- dehydrogenase β-D-galactoside heptyl]malate methylsulfanyl) in 23S rRNA hexadec-7- oxododec- kinase/ SAH phosphomethylpyrimidine kinase: CN62_RS06600 hypoxanthine PRPP dGTP [scaffold protein- -4-methylthiazole phosphatidyl- -L-cysteinyl- 2'-deoxycytidine acetylmuramoyl- UDP-N-acetyl- 3-phosphate oxopentanoate E2 protein] N 6 6-phospho-beta- glycogen/ 3-isopropylmalate butyl]malate 23S rRNA enoyl-[acp] 5-enoyl-[acp] kinase: CN62_RS06610 [acp] 1-acyl-sn-glycerol- 3-isopropylmalate 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- riboflavin phosphomethylpyrimidine 4-methyl-5-(2- uroporphyrinogen-III sn-glycerol xanthine branched-chain galactosidase: starch/alpha- dehydrogenase: nucleoside- (2Fe-2S)] complex hydroxyethylthiazole (3R)-3- [apolipoprotein] L-alanyl-γ-D- α-D-glucosamine 3-phosphate -lipoyl-L-lysine (uracil(1939)-C(5)) carrier-protein] carrier-protein] kinase: CN62_RS06610 5'-methylthioadenosine/ hydroxymethylpyrimidine/ phosphooxyethyl)thiazole protoporphyrinogen IX dehydrogenase: quinolinate cytidine glutamyl-L-lysyl- undecaprenyldiphospho- phosphoribosyltransferase: alpha-keto acid CN62_RS08685 glucan family CN62_RS08990 -methyltransferase triphosphate kinase: CN62_RS06565 hydroxyhexanoyl- acyltransferase: CN62_RS08990 reductase: reductase: bifunctional adenosylhomocysteine phosphomethylpyrimidine thiamine phosphate deaminase: muramoylpentapeptide beta-N- CN62_RS11605 dehydrogenase phosphorylase: diphosphatase: hydroxymethylpyrimidine/ [acyl-carrier D-alanyl-D-alanine CN62_RS10600 6-phospho-beta- 3-isopropylmalate RlmD: CN62_RS05405 CN62_RS05405 riboflavin kinase/ hydroxyethylthiazole nucleosidase: kinase: CN62_RS10480 synthase: nicotinate- ditrans,octacis- 1-palmitoyl-2- 3-isopropylmalate phosphomethylpyrimidine coproporphyrinogen III a 3-oxoacyl-[acp] a peptide CN62_RS06695 thymidine acetylglucosaminyltransferase: hypoxanthine subunit E2: galactosidase: CN62_RS13195 dehydrogenase: CN62_RS08070 CN62_RS11765 a [co-chaperone]- FAD synthetase: kinase: CN62_RS06600 CN62_RS07880 nucleotide protein] an N-acyl-(S- undecaprenyldiphospho- palmitoleoyl- a [apo BCAA dehydrogenase α-D- a 5- a (3R,7Z)-3-[+ 2 isozymes] a (3R,5Z)-3-[+ 2 isozymes] kinase: CN62_RS10480 CN62_RS06570 [+ 2 isozymes] CN62_RS06470 phosphoribosyltransferase: CN62_RS08595 CN62_RS08710 dehydrogenase: 4-methyl-5-(2- HMP-P dehydratase: acyl-carrier protein 6 CN62_RS09020 1939 dGMP [scaffold protein- CN62_RS08385 diphosphorylase diacyl-sn-glyceryl) pyrimidine- N-acetyl-(N-acetyl-β-D- sn-glycerol E2 protein] N -S-[3- glucopyranose maltotriose CN62_RS09020 methyluracil hydroxy-hexadec- hydroxydodec- S-ribosyl-L- thiamine phosphate UDP CN62_RS13890 D-galactopyranose 10-(methylsulfanyl) (2Fe-2S)] complex phosphooxyethyl) (carboxylating): protoporphyrin IX CN62_RS05420 -L-cysteinyl- glucosaminyl)muramoyl- methylbutanoyl]dihydrolipoyl- an alcohol 1-phosphate 7-(methylsulfanyl) in 23S rRNA HMP-PP homocysteine synthase: 3-oxoacyl-[acyl- 2'-deoxyuridine nucleoside 3-phosphate 6-phosphate -2-oxodecanoate 7-enoyl-[acp] 5-enoyl-[acp] FMN thiazole bifunctional IMP -2-oxoheptanoate CN62_RS12605 [lipoprotein] phosphorylase: L-alanyl-γ-D-glutamyl-L- L-lysine hydroxymethylpyrimidine CN62_RS06605 ferrochelatase: a (2E)-hex- carrier-protein] S-ribosylhomocysteine lysyl-D-alanyl-D-alanine protoporphyrinogen IX 2-enoyl-[acp] reductase: deoA bifunctional thiamine thioredoxin pathway lyase: CN62_RS05025 kinase/ NaMN CN62_RS07970 beta-ketoacyl- a [chaperone-ATP]- riboflavin kinase/ thiamine phosphate [acyl-carrier- CN62_RS05405 phosphate S-ribosylhomocysteinase: phosphomethylpyrimidine hexanoyl-[acyl- thymine [co-chaperone]- FAD synthetase: kinase: CN62_RS06610 nicotinate-nicotinamide protoheme carrier-protein] protein] [+ 2 isozymes] pyrimidine- 1-myristoyl- an (S)-2- a [protein] N-terminal- a (1->4)- a (7Z,10Z,13Z,16Z,19Z)-3- 3-[(5'- a (3R,5Z)-3- an (11Z)-3- synthase: an oxidized CN62_RS05040 5-oxo-L-proline metabolism quinoxaline-2- sn-glycero-3- a cis,cis-delta5,17-3- [scaffold protein- CN62_RS08385 nucleotide reductase: synthase II: nucleoside aryl-carrier protein a palmitoleoyl-[acp] sn-glycerol halocarboxylate formyl-L-methionine α-D-glucan oxodocosa-7,10,13,16,19- methylsulfanyl) hydroxy-tetradec- oxo-icos-11- CN62_RS06570 thioredoxin hydroxymethylpyrimidine/ a (3R)-3- carboxyl adenylate phosphoethanolamine hydroxyC36:2[acp] dATP (2Fe-2S)] complex adenylyltransferase: a 2,3,4-saturatedCN62_RS05410 phosphorylase: glycerophosphodiester haloacid peptide glycogen/ pentyl]malate 5-enoyl-[acp] enoyl-[acp] L-homocysteine phosphomethylpyrimidine protoporphyrin IX CN62_RS05395 hydroxyacyl-[acyl- a [protein] with a [protein] with acyl carrier 1-acyl-sn-glycerol-3-phosphate pentaenoyl-[acp]hypothetical hypothetical 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- FAD thiamine starch/alpha- 3-isopropylmalate nucleoside- nadD fatty acyl-[acp] an N-terminal an N-terminal deoA superpathway of purine deoxyribonucleosides degradation phosphodiesterase: dehalogenase: deformylase: protein: phosphate kinase: CN62_RS10480 3-hydroxyacyl-carrier protein] protein: 3-phosphate protein: dehydrogenase: carrier-protein] carrier-protein] thiamine CN62_RS07895 CN62_RS05105 CN62_RS09820 glucan family triphosphate thioredoxin- nicotinate adenine ferrochelatase: a hexanoyl-[acp] [acp] L-glutamine L-glutamate CN62_RS05390 acyltransferase: CN62_RS03855 CN62_RS03855 reductase: reductase: synthase: phosphorylase: CN62_RS08990 diphosphatase: thiamine diphosphate disulfide HMP-PP dinucleotide CN62_RS07970 glycerophosphodiester CN62_RS10600 haloacid peptide [+ 2 isozymes] CN62_RS05405 CN62_RS05405 CN62_RS06605 thiamine dehydratase: acyl carrier 1-myristoyl-2- a (3R,7Z,10Z,13[+Z ,162 isozymes]Z 3-isopropylmalate a cis,cis- a [chaperone- biosynthesis II (Bacillus) 3-oxoacyl-[acyl- 2'-deoxyguanosine dehalogenase: deformylase: CN62_RS13195 CN62_RS11765 an [2Fe-2S] reductase: diphosphokinase: NAD+ synthetase, CN62_RS05420 protein: phosphodiesterase: α-D- delta5,17-3- [+ 2 isozymes] [+ 2 isozymes] ADP]-[disordered- NAD(+) uracil 2-deoxy-α-D- palmitoleoyl- ,19Z)-3-hydroxydocosa- dehydrogenase: a (5Z)-3-oxo- a (3R,11Z)-3- 2-(2-carboxy-4- CN62_RS09830 protoheme carrier-protein] CN62_RS12140 acyl-carrier protein CN62_RS12845 CN62_RS10260 a (1->4)- dAMP cluster protein thiamine diphosphate L-cystathionine CN62_RS12380 glutamine 2'-deoxyadenosine CN62_RS03575 sn-glycerol glucopyranose 7,10,13,16,19- CN62_RS09020 oxo-C36:2-[acp] tetradec-5- hydroxy-icos- form scaffold thiamine synthetase: reductase: a [protein] with ribose 1-phosphate a quinoxaline-2- sn-glycerol a (2R)-2- an N-terminal L- α-D-glucan HMP-PP methylthiazol-5- dependent: ethanolamine a halide anion formate 1-phosphate 8-(methylsulfanyl) protein] complex biosynthesis I (E. coli) phosphate CN62_RS09710 3-phosphate hydroxy fatty acid methionyl-[protein] pentaenoyl-[acp] enoyl-[acp] 11-enoyl-[acp] yl)ethylthiamine phosphate cystathionine thiamine diphosphate CN62_RS09710 CN62_RS05405 an N-terminal 5- phosphopentomutase: AMP carboxyl-[aryl- 3-phosphate -2-oxooctanoate lipoate biosynthesis folate polyglutamylation purine-nucleoside 2-[(2R,5Z)- phosphate a reduced beta-ketoacyl- oxo-L-proline CN62_RS07140 carrier protein] gamma-synthase: lipoate salvage I phosphorylase: 2-carboxy-4- and incorporation II NAD + a trans-2- synthase: thioredoxin CN62_RS10120 [acyl-carrier- a 2,3,4-saturated 2-deoxy-D-ribose CN62_RS07170 HMP-PP methylthiazol-5(2H a tetrahydrofolate enoyl-[acyl- Pyrrolidone- an [Fe-S cluster a [disordered- CN62_RS06570 protein] fatty acyl-[acp] 5-phosphate thiamine octanoate carrier protein] γ-L-glutamyl purine-nucleoside N-acetyl-β-D-glucosamine- 1-stearoyl- DNA with adenine:7,8- 3-[(6'- a 3- a (9Z)-3-oxo- biosynthesis form [Fe-S] cluster )-ylidene]ethyl cys (R)-lipoate synthase II: carboxylate glutathione chitin maltohexaose a ribonucleoside thiamine thiamine lipoate-- 5-phosphate formate dihydro-8- phosphate diphosphate lipoate-- peptidase 1: purine-nucleoside phosphorylase: a palmitoyl-[acp] a malonyl-[acp] 1,6-anhydro-N- a palmitoyl-[acp] sn-glycerol methylsulfanyl) oxodocosanoyl- octadec-9- a malonyl-[acp] chaperone]-ATP scaffold protein] 4-aminobenzoate serine formate--tetrahydrofolate CN62_RS05410 2,3,4-saturated 2'-deoxyinosine beta-N- triphosphate IMP phosphate phosphate protein ligase: bifunctional 2-deoxyribose- CN62_RS07150 acetyl-β-D-muramate 3-phosphate glycogen/ oxoguanine mismatch hexyl]malate [acp] enoyl-[acp] protein ligase: biosynthesis fatty acyl- CN62_RS07285 phosphorylase: 3-oxoacyl-[acyl-carrier- beta-N- 1-acyl-sn-glycerol- anaerobic A/G-specific 3-isopropylmalate hypothetical 3-oxoacyl-[acyl- beta-ketoacyl- synthase: synthase: CN62_RS14575 folylpolyglutamate hydroxymethyltransferase: glyA ligase: CN62_RS08880 5-phosphate acetylhexosaminidase: starch/alpha- guanosine a [lipoyl-carrier glutathione-peroxide di-trans,poly-cis CN62_RS14575 a 3-oxooctanoyl- [+ 2 isozymes] CN62_RS07170 protein] reductase: 3-phosphate ribonucleoside- adenine protein: carrier-protein] [acyl-carrier- [acp]:NAD+ acetylhexosaminidase: CN62_RS13370 dehydrogenase: CN62_RS06570 CN62_RS06605 protein] N 6 - -undecaprenyl synthase/dihydrofolate [acp] aldolase: glucan family monophosphate thiamine redox reactions (lipoyl)adenylate chorismate : Aromatic Compound purine-nucleoside purine-nucleoside CN62_RS05405 CN62_RS13370 acyltransferase: triphosphate glycosylase: CN62_RS08990 CN62_RS03855 reductase: protein] synthase: CN62_RS04375 10 CN62_RS07200 beta-N- phosphorylase: reductase: thiamine phosphate octanoyl-L-lysine phosphate biosynthesis aminodeoxychorismate a 5,10-methylenetetrahydrofolate an N -formyltetrahydrofolate hypothetical CN62_RS10600 reductase: CN62_RS08875 [+ 2 isozymes] CN62_RS05405 synthase II: base-degraded CN62_RS05395 Biosynthesis phosphorylase: phosphorylase: beta-ketoacyl-[acyl- beta-N- 1-stearoyl- 3-isopropylmalate a (3R)-3- acyl carrier phosphate lipoate-- bifunctional 5-oxo-L-proline C1 Compound Utilization acetylhexosaminidase: CN62_RS13195 CN62_RS08985 GSSG (2E,6E)-farnesyl synthase, component protein: CN62_RS07150 CN62_RS07170 carrier-protein] synthase α-D- CN62_RS04400 an apurinic site hydroxydocosanoyl- [+ 2 isozymes] CN62_RS05410 thiamine salvage protein activation IPP protein ligase: bifunctional bifunctional D-glyceraldehyde acetylhexosaminidase: 2-palmitoyl- CN62_RS03670 adenine dehydrogenase: a (3R,9Z)-3- a 3- synthase: diphosphate I: CN62_RS06365 folylpolyglutamate CN62_RS03855 chorismate biosynthesis I acetaldehyde and Assimilation acyl-carrier protein a 2'-deoxyribonucleoside GMP 4-amino-4- 3-phosphate purine-nucleoside II: CN62_RS05410 CN62_RS03670 sn-glycerol N-acetyl-D- glucopyranose maltopentaose within DNA CN62_RS09020 [acp] hydroxy-octadec- oxodocosanoyl- thiamineCN62_RS06605 CN62_RS14575 synthase/dihydrofolate folylpolyglutamate folylpolyglutamate 5'-triphosphate formylaminopyrimidine a [lipoyl-carrier di-trans,octa-cis [+ 2 isozymes] 1,6-anhydro-N- chitin 1-phosphate 9-(methylsulfanyl) an apo acyl- a [lipoyl-carrier deoxychorismate synthase/dihydrofolate synthase/dihydrofolate phosphorylase: formate assimilation into 5,10- acyl-carrier protein a 3-oxooctadecanoyl-[acp] GlcNAc 3-phosphate glucosamine 9-enoyl-[acp] [acp] phosphate thiamine 6 synthase: CN62_RS04840 a (3R)-3- D-erythrose acetyl-β-muramate -2-oxononanoate carrier protein protein]-N -[(R) glutathione- -undecaprenyl 6 CN62_RS07150 holo-ACP protein]-N - synthase: CN62_RS04375 synthase: CN62_RS04375 4-phosphate methylenetetrahydrofolate diphosphate -dihydrolipoyl]- diphosphate hydroxyoctanoyl- aminomethylpyrimidine disulfide lipoyl-L-lysine biotin-carboxyl carrier 3-deoxy-7- glu synthase: bifunctional bifunctional [acp] L-lysine reductase: undecaprenyl- a tetrahydrofolate phosphoheptulonate CN62_RS10950 protein assembly acetyl-CoA 2-deoxy-α-D-ribose 1-phosphate formate an N-acetyl-β- 1-stearoyl- a plant soluble (1S,2R)-1- 3-[(3'- a 3- 1-myristoyl- a 1-acyl-sn thiaminase II: a holo acyl- diphosphatase: folylpolyglutamate folylpolyglutamate (3R)-3- CN62_RS06940 4-aminobenzoate synthase: formate-- a (3Z)-dec- CN62_RS06590 thiamine synthase/dihydrofolate synthase/dihydrofolate hydroxyoctanoyl- a [biotin an acyl-[acyl-carrier protein] a malonyl-[acp] D-hexosaminide a stearoyl-[acp] sn-glycerol a malonyl-[acp] heteroglycan C-(indol-3- methylsulfanyl) oxodocosanoyl- sn-glycerol -glycerol 3- carrier protein CN62_RS05570 CN62_RS10955 inosine 5'- 3-enoyl-[acp] ATP H O ser GTP diphosphate carboxyl-carrier phosphopentomutase: tetrahydrofolate beta-N- 3-phosphate glycogen/ 2 yl)glycerol propyl]malate [acp] 3-phosphate phosphate synthase: CN62_RS04840 synthase: CN62_RS04840 [acyl-carrier 3-oxoacyl-[acyl-carrier- 1-acyl-sn-glycerol- beta-ketoacyl- 3-isopropylmalate hypothetical 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 4-amino-2-methyl-5- di-trans,octa-cis- 3-deoxy-7- phosphate ligase: acetylhexosaminidase: starch/alpha- ATPase: nucleoside- protein] protein]-L-lysine CN62_RS07140 protein] reductase: 3-phosphate [acyl-carrier- 3-phosphate tryptophan protein: 3-phosphate 3-phosphate pyrimidinemethanol undecaprenyl phosphate 10 6 degradation CN62_RS08880 CN62_RS07950 dehydrogenase: glutathione a 5,10-methylenetetrahydrofolate an N -formyltetrahydrofolate bifunctional biotin- phosphoheptulonate N -L- 10 CN62_RS13370 glucan family synthase triphosphate dehydratase: an N - CN62_RS05405 acyltransferase: protein] CN62_RS08990 CN62_RS03855 acyltransferase: acyltransferase: synthase: threonylcarbamoyladenosine 37 2-deoxy-D-ribose 5-phosphate phosphorylase: ATPase: diphosphatase: CN62_RS05420 -[acetyl-CoA- pyrimidine beta-N- subunit beta: CN62_RS10600 CN62_RS10600 formyltetrahydrofolate beta-ketoacyl-[acyl- CN62_RS106001-stearoyl-2- synthase II: 3-isopropylmalate a (3R)-3-[+ 2 isozymes] 1-myristoyl-2- a 1-acyl-2- carboxylase] CN62_RS10960 -modified tRNA biosynthesis IMP acetylhexosaminidase: CN62_RS13195 CN62_RS10595 CN62_RS11475 CN62_RS11765 3-deoxy- ribonucleosides bifunctional carrier-protein] synthase CN62_RS05410 α-D- D-glyceraldehyde hydroxydocosanoyl- palmitoleoyl- palmitoyl-sn a (2E)-oct- IMP stearoyl-sn a (5Z)-3- + dehydrogenase: synthetase/ D-arabino- degradation CN62_RS03670 acyl-carrier protein a plant soluble H phosphate ADP trp GMP thr 2-deoxyribose-5-phosphate methylenetetrahydrofolate II: CN62_RS05410 -glycerol 3- acyl-carrier protein oxododec- glucopyranose 3-phosphate CN62_RS09020 [acp] sn-glycerol -glycerol 3- 2-enoyl-[acp] biotin operon dehydrogenase: an N-acetyl-β- heteroglycan Secondary Metabolite Biosynthesis heptulosonate cytidine aldolase: CN62_RS07200 dehydrogenase/ an alcohol 6-(methylsulfanyl) 3-phosphate phosphate threonylcarbamoyl- CN62_RS13760 acyl-carrier protein a 3-oxoacyl-[acp] phosphate 5-enoyl-[acp] 1-phosphate octanoyl-[acyl- repressor: 7-phosphate cytidine deaminase: D-hexosamine -2-oxohexanoate AMP synthase: XMP methenyltetrahydrofolate carrier-protein] CN62_RS11865 3-dehydroquinate CN62_RS06695 autoinducer AI-2 biosynthesis I CN62_RS08040 acetaldehyde D-glyceraldehyde 3-phosphate cyclohydrolase: reductase: a [biotin carboxyl- synthase: (L-threonylcarbamoyl) [+ 2 isozymes] Amino Acid Biosynthesis CN62_RS07125 superpathway of L- carrier protein]-N adenylate 1518 a cis,cis-delta9,21- 1-palmitoyl- superpathway of branched chain amino acid biosynthesis L-lysine biosynthesis II superpathway of L-methionine biosynthesis (transsulfuration) L-tryptophan biosynthesis CN62_RS05395 CN62_RS09515 uridine adenine / sn-glycerol isoleucine biosynthesis I L-methionine biosynthesis II (plants) 6 a 5,10- a 2,3,4-saturated a 2,3,4-saturated 2- a sulfurated a (5Z)-tetradec- a maltodextrin DNA with lesion SAM -biotinyl-L-lysine an acetyl-[acp] a malonyl-[acp] hydrogen cyanide a malonyl-[acp] 1519 3-hydroxyC40:2- sn-glycerol pyrimidine-nucleoside fatty acyl-[acp] lysophosphatidate [sulfur carrier] 5-enoyl-[acp] adenine in 16S rRNA GTP 3-phosphate dIDP an octanoyl-[acp] 3-dehydroquinate methenyltetrahydrofolate glycogen/ ribosomal RNA excinuclease [acp] 3-phosphate beta-ketoacyl-[acyl- 1-acyl-sn-glycerol- rhodanese beta-ketoacyl- hypothetical 1-acyl-sn-glycerol- glycerol-3- oxaloacetate pyruvate oxaloacetate chorismate phosphorylase: deoA starch/alpha- nucleoside- thr asp L-homoserine 6 bifunctional carrier-protein] synthase small subunit GTP ABC subunit UvrA: protein: phosphate aspartate type I 3- an N -L- acetyl-CoA 3-phosphate domain- [acyl-carrier- 3-phosphate 3-oxoacyl-[acyl- 37 uracil xanthosine methylenetetrahydrofolate glucan family methyltransferase cyclohydrolase CN62_RS04340 diphosphate acetolactate aspartate kinase: a [biotin carboxyl- threonylcarbamoyladenine II: CN62_RS05410 acyltransferase: containing protein] CN62_RS03855 acyltransferase: acyltransferase: aminotransferase: aspartate aminotransferase: hypothetical protein: SAH dehydroquinate phosphorylase: kinase: threonine carrier-protein] dehydrogenase/ 6 A: CN62_RS123951518 I FolE: excinuclease CN62_RS07245 CN62_RS11385 synthase: CN62_RS05370 CN62_RS11600 homoserine kinase: carrier-protein dehydratase: aroD in tRNA 3-oxoacyl-[acyl-carrier- CN62_RS10600a 2,3,4-saturated protein: synthase II: N -dimethyladenine a cis,cis-[+ 2 isozymes] 1-palmitoyl-2-CN62_RS10600 1-(18- dehydratase: CN62_RS11385 reductase: 6 methenyltetrahydrofolate CN62_RS13195 7,8- CN62_RS04845 CN62_RS12270 CN62_RS05505 L-aspartyl- dimer]-N - purine-nucleoside protein] reductase: CN62_RS03810 CN62_RS05410 /N 6 -dimethyladenine 1519 ABC subunit B: asp CN62_RS09445 5'-methylthioadenosine/ 1,2-diacyl-sn a (7Z)-3-oxo- α-D- delta9,21-3- palmitoleoyl- hydroxyoleoyl) CN62_RS05530 CN62_RS05405 biotinyl-L-lysine 3-dehydroshikimate phosphorylase: cyclohydrolase: acyl-carrier protein an unsulfurated dihydroneopterin formate CN62_RS08925 dITP CN62_RS05510 4-phosphate anthranilate PRPP adenosylhomocysteine CN62_RS05405 -glycerol 3- thiocyanate acyl-carrier protein hexadec-7- glucopyranose a maltodextrin in 16S rRNA oxo-C40:2-[acp] sn-glycerol -sn-glycrol (2Z)-2-aminobut- asp acetyl-CoA CN62_RS07150 CN62_RS07125 [sulfur carrier] 3'-triphosphate DNA without O-phospho-L-homoserine beta-ketoacyl- phosphate enoyl-[acp] 1-phosphate 3-phosphate 3-phosphate aspartate- nucleosidase: acetyl-CoA shikimate an acetoacetyl-[acp] acyl-carrier protein lesion aspartate kinase: (S)-2-acetolactate 2-enoate [acyl-carrier- carboxylase purine-nucleoside a 5,10- CN62_RS07880 carboxylase dehydrogenase: CN62_RS05370 semialdehyde aspartate kinase: anthranilate protein] carboxyl Respiration methylenetetrahydrofolate biotin carboxylase phosphorylase: ketol-acid dehydrogenase: CN62_RS05370 phosphoribosyltransferase: cystathionine gamma- CN62_RS09520 S-ribosyl-L-homocysteine synthase II: transferase: CN62_RS07170 L-aspartyl- reductoisomerase: CN62_RS08000 CN62_RS11490 synthase: CN62_RS10120 subunit: a 2'- an L-1- CN62_RS05410 CN62_RS05430 2-oxoisovalerate decarboxylation to isobutanoyl-CoA a [formate C 1-cis-vaccenoyl- a cytosine 967 a guanine 966 a cis,cis-delta9,27- a cis,cis- CN62_RS05515 CN62_RS05425 shikimate a reduced a (7Z)-hexadec- a (3Z)-dodec- a glycogen 4-phosphate CN62_RS05435 xanthine SAM acetyltransferase]- a palmitoleoyl-[acp] sn-glycerol- a malonyl-[acp] a malonyl-[acp] deoxyribonucleoside [DNA] 3-hydroxyC46:2- delta21,39-3- phosphatidyl- (2R)-2,3- 2-iminobutanoate L-aspartate 4- L-aspartyl-4-phosphate S-ribosylhomocysteine in 16S rRNA in 16S rRNA IDP L-cystathionine a 3-oxodecanoyl- a [carboxyl-carrier an [apo BCAA flavodoxin 7-enoyl-[acp] 3-enoyl-[acp] glycogen/ 5'-triphosphate sn-glycerol semialdehyde N-(5-phosphoribosyl)-anthranilate shikimate kinase: purine ribonucleosides degradation glycine pyruvate formate 1-acyl-sn-glycerol-3-phosphate beta-ketoacyl- beta-ketoacyl- DNA 16S rRNA 16S rRNA [acp] hypothetical hydroxyC58:2- aspartate- dihydroxy-3- lyase: CN62_RS05025 [acp] 6 dehydrogenase starch/alpha- nucleoside- protein dimer]-N (cytosine(967)-C(5) (guanine(966)-N(2) protein: [acp] hypothetical lipid kinase: semialdehyde methylbutanoate aspartate-semialdehyde CN62_RS09490 6 lyase-activating 3-phosphate [acyl-carrier- [acyl-carrier- polymerase IV: 4-hydroxy- S-ribosylhomocysteinase: hypothetical -carboxybiotinyl- E2 protein] N branched-chain glucan family diphosphate phosphoribosylanthranilate protein: acyltransferase: protein] protein] CN62_RS05575 )-methyltransferase )-methyltransferase CN62_RS03855 protein: CN62_RS08135 dehydrogenase: 2,3-dihydroxy- tetrahydrodipicolinate dehydrogenase: cystathionine beta- CN62_RS05040 shikimate 3- -lipoyl-L-lysine alpha-keto acid phosphorylase: kinase: protein: L-lysine adenosine RsmB: RsmD: CN62_RS03855 CN62_RS08000 CN62_RS08000 isomerase: CN62_RS11480 CN62_RS12355 a [formate C CN62_RS106001-cis-vaccenoyl- synthase II: synthase II: [+ 6 isozymes] a cis,cis-[+ 2 isozymes] 1-(3-sn- isovalerate synthase: lyase: CN62_RS06405 CN62_RS03855 phosphate dehydrogenase urate CN62_RS13195 CN62_RS11135 CN62_RS12325 CN62_RS12270 2-oxobutanoate AI-2 dihydrolipoyl a flavodoxin CN62_RS05410 CN62_RS05410 α 2 a cis,cis-[+ 2 isozymes] phosphatidyl) L-aspartate 4- dehydratase: CN62_RS08005 1-(2-carboxyphenylamino)-1- subunit E2: met 5'-deoxyadenosine acetyltransferase]- 2-palmitoleoyl- a (9Z)-3-oxo- a (5Z)-3-oxo- -D- [DNA] a 5-methylcytosine 967 an N - delta9,27-3- L-aspartate 4-semialdehyde [+ 2 isozymes] 3-phosphoshikimate 1- semiquinone acyl-carrier protein 966 delta21,39-3- -sn-glycerol ITP CN62_RS13300 (2S,4S)-4- deoxy-D-ribulose 5-phosphate dehydrogenase: CN62_RS08595 glycin -2-yl radical sn-glycerol- acyl-carrier protein octadec-9- acyl-carrier protein tetradec-5- glucopyranose maltotetraose methylguanine oxo-C46:2-[acp] semialdehyde acetolactate a (3R)-3- carboxyvinyltransferase: in 16S rRNA oxo-C58:2-[acp] hydroxy-2,3,4,5- L-homocysteine 2-aminoprop-2-enoate CN62_RS08590 1-phosphate in 16S rRNA 3-phosphate 3-methyl-2- synthase: indole-3-glycerol- hydroxydecanoyl- 3-phosphate enoyl-[acp] enoyl-[acp] homoserine tetrahydrodipicolinate homoserine CN62_RS09495 oxobutanoate CN62_RS05505 phosphate synthase: superpathway [acp] 5-enolpyruvoyl- dehydrogenase: dehydrogenase: 5-methyltetrahydropteroyltriglutamate- an [apo BCAA CN62_RS05510 4-hydroxy- CN62_RS11485 of L-threonine (2R,4S)-2-methyl-2,4- 3-hydroxydecanoyl- an [apo BCAA dehydrogenase CN62_RS09450 CN62_RS09450 shikimate 3- dehydrogenase 1-stearoyl- a [DNA]-3'- a 5'-phospho- a [release factor]- a double-stranded a cis,cis-delta7,25- a cis,cis- tetrahydrodipicolinate - homocysteine S- dihydroxydihydrofuran-3-one 6 xanthosine adenosine inosine guanosine an N-formyl-L- + maltoheptaose 2-isopropylmalate branched-chain biosynthesis [acp] dehydrase: phosphate 6 E2 protein] N -S-[2- NAD 3'-dephospho- 3-hydroxyC44:2- delta19,37- ser (S)-2-aceto-2- (1S,2R)-1-C-(indol-3- E2 protein] N an oleoyl-[acp] sn-glycerol hydroxyl [DNA] an oleoyl-[acp] a malonyl-[acp] ATP L-glutamine oligonucleotide ITP reductase: methyltransferase: CN62_RS06040 methylpropanoyl]dihydrolipoyl- methionylaminoacyl-tRNA glycogen/ L-homoserine synthase: amino acid hydroxybutanoate L-homoserine yl)glycerol 3-phosphate 2-iminopropanoate CN62_RS05420 chorismate -dihydrolipoyl- 3-phosphate DNA CoA peptide chain bifunctional [acp] hypothetical 3-hydroxy- CN62_RS10290 oxaloacetate peptide deformylase: 1-acyl-sn-glycerol- beta-ketoacyl- dephospho- L-serine ammonia- CN62_RS09025 aminotransferase: synthase: L-lysine ligase starch/alpha- release factor oligoribonuclease/ C56:2-[acp]hypothetical nucleoside- ketol-acid aspartate met a (2E)-dec- L-lysine CN62_RS09820 3-phosphate [acyl-carrier- protein: lyase, iron-sulfur- (S)-2,3,4,5- tryptophan synthase: purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside glucan family CoA kinase: triphosphate homoserine CN62_RS07265 reductoisomerase: aminotransferase: CN62_RS09510 (NAD(+)) N(5)-glutamine PAP CN62_RS03855 protein: CN62_RS11470 (2R,4S)-2-methyl-2,3,3,4- 2-enoyl-[acp] peptide deformylase: acyltransferase: protein] CN62_RS07800 dependent, kinase: (2S)-2- tetrahydrodipicolinate homoserine O- phosphorylase: phosphorylase: phosphorylase: phosphorylase: LigA: ligA phosphorylase: methyltransferase: NrnA: CN62_RS03855 diphosphatase: CN62_RS05515 CN62_RS11385 tetrahydroxytetrahydrofuran CN62_RS10600 synthase II: [+ 2 isozymes] subunit beta: CN62_RS11475 decanoyl-[acyl- chorismate CN62_RS07150 CN62_RS07170 CN62_RS07170 CN62_RS07170 CN62_RS10260 1-stearoyl-2- CN62_RS13195 ADP coenzyme A H + a cis,cis- CN62_RS11765 CN62_RS09445 isopropylmalate 2,3,4,5- succinyltransferase: CN62_RS08035 CN62_RS09215 a cis,cis-[+ 2 isozymes] (R)-2,3-dihydroxy- superpathway of L-homoserine and L-methionine biosynthesis asp branched-chain formate a L-methionylaminoacyl-tRNA acyl-carrier protein oleoyl-sn-glycerol CN62_RS05410an (11Z)-3- α-D- 5 delta7,25-3- CN62_RS03870 val tetrahydropyridine- CN62_RS10395 tryptophan synthase pyruvate carrier-protein] purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside NMN AMP [DNA] a [release factor]-N a nucleoside 5'- O-phospho- 3-methylpentanoate Fermentation delta19,37-3- IMP subunit beta: reductase: alpha-keto acid 3-phosphate acyl-carrier protein oxo-icos-11- glucopyranose maltohexaose -methyl-L-glutamine oxo-C44:2-[acp] pyruvate L-homoserine 2,6-dicarboxylate N- cys phosphorylase: phosphorylase: phosphorylase: phosphorylase: monophosphate oxo-C56:2-[acp] 2,3-dihydroxy-3- CN62_RS11475 aspartate kinase: L-phenylalanine CN62_RS05395 dehydrogenase enoyl-[acp] 1-phosphate acetyltransferase: asp Aminoacyl-tRNA Charging CN62_RS07170 CN62_RS07150 CN62_RS07150 CN62_RS07150 threonine methylvalerate O-succinyl-L-homoserine CN62_RS05370 biosynthesis I subunit E2: pyruvate 2-isopropylmaleate CN62_RS13150 synthase: hydro-lyase: a decanoyl-[acp] Amine and Polyamine CN62_RS08595 fermentation ser indole α-D-ribose- 1-myristoyl- a linear malto- a cis,cis-delta5,23- a cis,cis- a [lipoyl-carrier (3R,5S)-3- L-2-acetamido-6- aspartate kinase: tRNA charging Biosynthesis a ring-opened 7- maltopentaose a [protein]- an unsulfurated a 3-oxohexacosanoyl- CN62_RS12855 CN62_RS13300 L-aspartyl- chorismate to (R)-acetoin II 1-phosphate a cis- sn-glycerol FAD 6 glycine biosynthesis I methylguanine in DNA a myristoyl-[acp] sn-glycerol oligosaccharide L-threonine cys 3-hydroxyC42:2- delta17,35-3- protein]-N -[(R) hydroxy-1- (S)-3-methyl-2- oxoheptanedioate cystathionine gamma- CN62_RS05370 4-phosphate chorismate 3-oxoacyl-[acyl- pyrimidine deoxyribonucleotides vaccenoyl-[acp] 3-phosphate glycogen/ glycogen/ [sulfur carrier] [acp] tryptophan synthase putrescine biosynthesis II pyruvate S-methyl-5'-thioadenosine phosphopentomutase: DNA- 3-phosphate FAD:protein FMN cysteine hypothetical [acp] hypothetical hydroxyC54:2- -dihydrolipoyl]- pyrroline-5- serine serine thr mutase: carrier-protein] glycerol-3- 1-acyl-sn-glycerol- RS11225 oxopentanoate synthase: CN62_RS10120 subunit beta: arginine-- acetolactate dephosphorylation formamidopyrimidine starch/alpha- starch/alpha- transferase: [acp] hypothetical L-lysine carboxylate thr thr (2R,3S)-3- aspartate- arg degradation IV CN62_RS07140 phosphate 3-phosphate desulfurase: protein: protein: dihydrolipoyl pyrroline-5- L-aspartyl-4-phosphate CN62_RS09205 ser tRNA ligase: reductase: nucleoside-triphosphate glycosylase: glucan family glucan family CN62_RS09890 branched-chain CN62_RS11475 semialdehyde synthase: acyltransferase: acyltransferase: CN62_RS08320 CN62_RS03855 CN62_RS03855 protein: carboxylate threonine isopropylmalate prephenate CN62_RS05405 S-methyl-5'- D-ribose 5- dehydrogenase: amino acid serine CN62_RS13055 an L-arginyl- arg Glycolysis CN62_RS05505 diphosphatase: CN62_RS07795 phosphorylase: phosphorylase: CN62_RS03855 reductase: dehydratase: L-cystathionine dehydrogenase: phosphate 2,6-diamino-4- CN62_RS072451-cis-vaccenoyl- CN62_RS106001,2-dimyristoyl- a [protein]-FMN- [+ 3 isozymes] a (3R)-3-[+ 2 isozymes] a cis,cis-[+ 2 isozymes] CN62_RS08590 3-isopropylmalate N-acetyl-L,L-2,6- aspartate-semialdehyde Arg beta-ketoacyl- thioadenosine CN62_RS11765 an apurinic site CN62_RS13195 CN62_RS13195 AMP a [lipoyl-carrier aminotransferase: trp CN62_RS08000 prephenate hydroxymethyltransferase: glyA [tRNA ] CN62_RS05510 5'-methylthioadenosine/ L-threonine a sulfurated a cis,cis-[+ 2 isozymes] CN62_RS07665 serine serine CN62_RS05530 dehydrogenase: Arg dCTP dCMP hydroxy-5-(N-methyl) acyl-carrier protein sn-glycerol- acyl-carrier protein sn-glycerol α-D- α-D- ala hydroxyhexacosanoyl- delta5,23-3- 6 RS11120 CN62_RS07265 diaminopimelate dehydrogenase: a tRNA [acyl-carrier- (S)-2-acetolactate within DNA a linear malto- [sulfur carrier] delta17,35-3- protein]-N - Hyp thr thr dehydratase: gly glycolysis III (from glucose) adenosylhomocysteine formamidopyrimidine (2Z)-2-aminobut- CN62_RS08990 N-acetyl- L-aspartate 4- 3-phosphate 3-phosphate glucopyranose glucopyranose maltotetraose [acp] oxo-C42:2-[acp] lipoyl-L-lysine cystathionine beta- CN62_RS08000 CN62_RS09485 protein] agmatine nucleosidase: oligosaccharide oxo-C54:2-[acp] 2-enoate semialdehyde acetolactate 1-phosphate 1-phosphate 3-isopropylmalate ile diaminopimelate synthase II: lyase: CN62_RS06405 3-phenyl-2- CN62_RS07880 deoxyuridine dehydrogenase: deacetylase: L-aspartate 4-semialdehyde homoserine CN62_RS05410 D-glucopyranose decarboxylase: oxopropanoate agmatine deiminase: MTR 5'-triphosphate CN62_RS09020 CN62_RS13145 dehydrogenase: a 3- CN62_RS09590 decaprenyl-diphospho-N- UDP-N-acetyl- 1-stearoyl- 1-palmitoyl- a carboxy- a long-linear a cis,cis-delta7,19- a cis,cis- Peptide RS08190 Peptide L-asparagine cysteine-- CN62_RS07610 glucokinase: nucleotidohydrolase: an acyl-[acyl- (R)-mevalonate 1-(18-hydroxyoleoyl)- a 3-oxotetracosanoyl- a cis-delta21-3- 2-aminoprop-2-enoate homoserine CN62_RS09450 aspartate cys oxododecanoyl- α α-D-glucan 3-hydroxyC38:2- delta15,33- (2S)-2-isopropyl- L,L- L-homocysteine biosynthesis II tRNA ligase: CN62_RS06380 (R)-acetoin CN62_RS03495 acetylmuramoyl-pentapeptide -D-glucosamine sn-glycerol a palmitoyl-[acp] sn-glycerol cys adenylated-[ThiS sn-glycrol 3-phosphate cys dehydrogenase: aminotransferase: carrier protein] glycogen/ diphosphate [acp] oxo-C40:1-[acp] 2-iminobutanoate 3-oxosuccinate [acp] N-carbamoylputrescine undecaprenyldiphospho- 3-phosphate 3-phosphate sulfur-carrier protein] 1-acyl-sn-glycerol- hypothetical [acp] hypothetical 3-hydroxy hypothetical diaminopimelate CN62_RS06065 an L-cysteinyl- nucleoside-triphosphate 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- cysteine diphosphomevalonate CN62_RS09450 L-homoserine CN62_RS11385 hypothetical D-glucopyranose muramoylpentapeptide beta-N- starch/alpha- C52:2-[acp]hypothetical lanthionine L-proline 5-methyltetrahydropteroyltriglutamate- Cys diphosphatase: 3-phosphate 3-phosphate desulfurase: 3-phosphate protein: protein: protein: L-alanine asp [tRNA ] protein: N-carbamoylputrescine 6-phosphate acetylglucosaminyltransferase: glucan family decarboxylase: synthetase: Peptide RS12260 Peptide - homocysteine S- Cys acyltransferase: CN62_RS03855 CN62_RS03855 protein: CN62_RS03855 biosynthesis I asparagine phe a tRNA CN62_RS11765 acyltransferase: acyltransferase: CN62_RS08320 CN62_RS05210 biosynthesis I L-homoserine homoserine CN62_RS03855 amidase: glucose-6- CN62_RS06470 phosphorylase: CN62_RS03855 CN62_RS05195 methyltransferase: CN62_RS06040 dUTP dUMP CN62_RS10600 CN62_RS10600 [+ 3 isozymes] 1-[18-hydroxyoeoyl]-2-CN62_RS10600 [+ 2 isozymes] [+ 2 isozymes] [+ 2 isozymes] 2-iminopropanoate synthetase A: kinase: CN62_RS07615 decaprenyl-pyrophosphoryl- a 1-stearoyl 2- CN62_RS13195 a (3R)-3- a cis,cis- a cis-delta21-3- 4-methyl-2- 3-methyl-2- [+ 2 isozymes] phosphate dipalmitoyl IPP a cis,cis-[+ 2 isozymes] CN62_RS12330 UDP (N-acetylglucosamine)-N- acyl-carrier protein acyl-sn-glycerol acyl-carrier protein a thiocarboxy- α-D- [18-hydroxy-lioleoyl]-sn hydroxytetracosanoyl- delta7,19-3- hydroxyC40:1- lanthionine 2-oxobutanoate oxopentanoate glu meso- homoserine O- CN62_RS09445 a (3R)-3- isomerase: pgi AMP ala a long-linear oxobutanoate met phosphatidate -glycerol 3-phosphate delta15,33-3- Peptide RS05135 Peptide glutamate branched-chain diaminopimelate succinyltransferase: asn hydroxydodecanoyl- putrescine Aldehyde acetylmuramyl-(pentapeptide) 3-phosphate [ThiS-Protein] glucopyranose [acp] oxo-C38:2-[acp] [acp] branched-chain O-phospho- 5-hydroxy-CTP 5-hydroxy-CMP α-D-glucan oxo-C52:2-[acp] acetolactate amino acid F6P 1-phosphate 5-kinase: CN62_RS10395 L-homoserine [acp] Degradation synthase: amino acid diaminopimelate gln CN62_RS07655 aminotransferase: (3R)-3- Amino Acid Degradation CN62_RS05505 aminotransferase: γ-L-glutamyl decarboxylase: pyruvate threonine 6-phosphofructokinase: methylglyoxal CN62_RS07265 cys O-succinyl-L-homoserine hydroxydodecanoyl- a DNA containing a [pyruvate dehydrogenase 1-cis-vaccenoyl- Peptide RS07270 Peptide CN62_RS07265 5-phosphate CN62_RS12360 an L-glutaminyl- 1-cis-vaccenoyl- a cis,cis- CN62_RS05510 synthase: CN62_RS07490 degradation I seleno-L- a [protein]- a cis- a nucleoside a [ThiI sulfur-carrier 6 1-cis-vaccenoyl-sn- a cis-delta19-3- val Gln [acyl-carrier protein] S methyl a ribonucleic acid E2 protein] N - roseoflavin sn-glycerol- [tRNA ] p sn-glycerol- cys delta13,31- a protein gamma-glutamyl- CN62_RS12855 L-threonine homocysteine L-cysteine vaccenoyl-[acp] triphosphate protein]-L-cysteine glycerol-3-phosphate ATP oxo-C38:1-[acp] (S)-2-aceto-2- L-methionine biosynthesis III Gln dehydratase: β-D-fructose 1,6- phosphotriester dihydrolipoyl-L-lysine 5'-phosphate 3-phosphate leu lys cystathionine gamma- a tRNA degradation I L-serine degradation L-asparagine methylated-DNA-- 1-acyl-sn-glycerol-3-phosphate DNA-directed cysteine 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 3-hydroxy hypothetical hydroxybutanoate phosphate bisphosphate methylglyoxal 5-methyltetrahydropteroyltriglutamate- dihydrolipoyl metalloprotease synthase: CN62_RS10120 CN62_RS05420 degradation I [protein]-cysteine S- desulfurase: 3-phosphate bifunctional C50:2-[acp]hypothetical protein: reductase: thr lactoylglutathione 3-phosphate RNA polymerase 3-phosphate Peptide RS06460 Peptide ketol-acid - homocysteine S- dehydrogenase: riboflavin kinase/ protein: RseP: L-homoserine a (2E)-dodec- methyltransferase: acyltransferase: subunit alpha: CN62_RS08320 acyltransferase: acyltransferase: CN62_RS03855 CN62_RS07660 thr ser lyase: methyltransferase: CN62_RS06040 CN62_RS08590 CN62_RS04710 reductoisomerase: L-glutamate L-cystathionine fructose- CN62_RS09855 CN62_RS10600 FAD synthetase: CN62_RS03855 homoserine O- L-cysteine biosynthesis I 2-enoyl-[acp] threonine asn CN62_RS06635 a DNA without CN62_RS106001,2-dicis- CN62_RS04555 a [ThiI sulfur- [+ 3 isozymes] a [pyruvate dehydrogenase 1-cis-vaccenoyl- 1,2-dicis- CN62_RS10600 a cis-delta19-3-[+ 2 isozymes] CN62_RS05515 L-glutamate-5- biosynthesis III bisphosphate L-serine ammonia- a [protein]-S- CN62_RS08385 a cis,cis-[+ 2 isozymes] ala acetyltransferase: SeMet S methyl 6 2-palmitoleoyl-sn- roseoflavin adenine vaccenoyl- a peptide glutamyl-tRNA dodecanoyl-[acyl- dehydratase: asparaginase: lactoylglutathione p acyl-carrier protein vaccenoyl- [+ 3 isozymes] carrier protein]-S- ala E2 protein] N -lipoyl-L-lysine hydroxyC38:1- (R)-2,3-dihydroxy- semialdehyde glu aldolase: lyase, iron-sulfur- methyl-L-cysteine delta13,31-3- predicted CN62_RS10395 synthetase: CN62_RS05530 CN62_RS12460 phosphotriester phosphatidate a ribonucleic acid sulfanyl-L-cysteine glycerol-3-phosphate dinucleotide phosphatidate [acp] O-acetyl-L- 2-oxoglutarate cystathionine beta- carrier-protein] CN62_RS04660 (2Z)-2-aminobut- dependent, lyase: ABC 3-methylpentanoate alanine hydrogen sulfide ser oxo-C50:2-[acp] Peptide Peptide homoserine NADP-specific CN62_RS12860 an L-glutamyl- reductase: asp CN62_RS07760 racemase: lyase: CN62_RS06405 fructose- 2-enoate subunit beta: (R)-S- transporter 2,3-dihydroxy-3- serine O-acetyltransferase: Glu glutamate [tRNA ] CN62_RS05395 CN62_RS03870 of a peptide methylvalerate L-alanine CN62_RS10945 O-acetylhomoserine glu bisphosphate 2-aminoprop- lactoylglutathione L-lactaldehyde CN62_RS06055 a tRNA phosphoenol an [HPr]- 1-palmitoyl- 2,3-bis-O- 1402 a 1-alkyl-sn a cis,cis- (S)-1-pyrroline- aminocarboxypropyltransferase/ dehydrogenase: 2-amino-6-[1-hydroxyethyl]- a cis- an acyl-[acyl- sn-glycerol a cytidine a 3-oxooctadecanoyl- a cis-delta17-3- hydro-lyase: biosynthesis III 2-aminoprop-2-enoate aldolase: 2-enoate degradation 2-oxobutanoate -glycerol 3- delta11,29- D-ala CN62_RS09240 L-homocysteine O-acetyl-L-serine a dodecanoyl-[acp] L-aspartate 7-methyl-7,8-dihydropterin pyruvate L-histidine sn-glycerol (geranylgeranyl) in 16S rRNA a protein Peptide RS10135 Peptide CN62_RS13300 5-carboxylate cysteine synthase: CN62_RS08820 CN62_RS06115 (anaerobic) vaccenoyl-[acp] carrier protein] 3-phosphate CTP [acp] oxo-C36:1-[acp] degradation I phosphoenolpyruvate- 3-phosphate branched-chain -sn-glycerol 16S rRNA hypothetical phosphate 3-hydroxy hypothetical glu 2-iminobutanoate 2-amino-4-hydroxy-6- 1-acyl-sn-glycerol- glycerol-3- 1-acyl-sn-glycerol- (S)-3-methyl-2- cys pyrroline-5- -protein alpha-keto acid (cytidine(1402)-2'-O) C48:2-[acp]hypothetical L-homocysteine 5-methyltetrahydropteroyltriglutamate- O-acetylhomoserine (S)-lactaldehyde hydroxymethyldihydropteridine 3-phosphate phosphate 1-phosphate CDP-archaeol protein: 3-phosphate protein: endopeptidase: oxopentanoate cysteine carboxylate aminocarboxypropyltransferase/ 3-oxoacyl-[acyl- acyl-ACP (R)-lactate lactaldehyde phosphotransferase: dehydrogenase -methyltransferase: protein: - homocysteine S- isoleucine-- triose-phosphate asp diphosphokinase: CN62_RS04850 acyltransferase: acyltransferase: synthase: CN62_RS03855 acyltransferase: CN62_RS03855 CN62_RS10700 desulfurase: reductase: cysteine synthase: CN62_RS08820 ile carrier-protein] thioesterase: 2-iminopropanoate reductase: [1-(2-amino-7-methyl-4-oxo- CN62_RS08655 subunit E2: CN62_RS07685 CN62_RS03855 Peptide RS03595 Peptide branched-chain 5-methyltetrahydropteroyltriglutamate- methyltransferase: CN62_RS06040 tRNA ligase: isomerase: an [HPr protein]- CN62_RS10600 CN62_RS07245 unsaturatedCN62_RS04705 a 2'-O- [+ 2 isozymes] a 2-acyl-1-alkyl-CN62_RS10600 [+ 2 isozymes] CN62_RS07345 CN62_RS07665 2-iminopropanoate CN62_RS09655 aspartate 1-palmitoyl-2- a 1-acyl-sn a (3R)-3- a cis-delta17-3- amino acid - homocysteine S- reductase: CN62_RS13445 7,8-dihydro-3H-pteridin- π CN62_RS08595 1402 a cis,cis-[+ 2 isozymes] ala RS05345 ala cysteine synthase CN62_RS10760 an L-isoleucyl- CN62_RS10385D-glyceraldehyde aminotransferase: (S)-propane- N -phospho- pyruvate acyl-carrier protein cis-vaccenoyl acyl-carrier protein -glycerol 3- CDP-archaeol methylcytidine hydroxyoctadecanoyl- sn-glycerol hydroxyC36:1- a peptide [+ 3 isozymes] CN62_RS05405 DHAP 6-yl)]ethyl diphosphate delta11,29-3- aminotransferase: methyltransferase: CN62_RS06040 met A: CN62_RS13685 Ile 2-oxobutanoate L-histidine NADH CO propanoyl-CoA in 16S rRNA 3-phosphate pro [tRNA ] 3-phosphate CN62_RS11385 1,2-diol phosphatidate 2 phosphate [acp] [acp] CN62_RS07265 ala Ile oxo-C48:2-[acp] a tRNA beta-ketoacyl- laurate oxaloacetate pyruvate Peptide RS05805 Peptide met cys [acyl-carrier- pyruvate ile protein] 6 a purine RS11610 a purine pyruvate an O - 1-palmitoyl- (E)-1-(L-cystein-S- a [2-oxoglutarate 527 a cis,cis- 6-(hydroxymethyl) a [protein]- a guanine sn-glycerol a cis-delta15-3- a nucleoside synthase II: L-glutamine sn-glycerol an alkylated DNA dehydrogenase E2 protein] palmitoleate -7,8-dihydropterin methylguanine sn-glycerol a myristoyl-[acp] a stearoyl-[acp] yl)-N-hydroxy-2-(4- in 16S rRNA delta19,31-3- 13-DPG propanoyl-CoA L-cysteine 3-phosphate 6 3-phosphate oxo-C34:1-[acp] diphosphate gln RS05545 gln CN62_RS05410 degradation I in DNA DNA-3- N -dihydrolipoyl-L-lysine ribosomal RNA hydroxyC50:2- leucine-- biosynthesis I (from Amine and Polyamine Degradation 2-amino-4-hydroxy-6- methylated-DNA-- 3-phosphate 1-acyl-sn-glycerol- glycerol-3- hydroxyphenyl)ethan-1-iminecystathionine glycerol-3- hypothetical nucleoside- leu lauroyl-CoA methyladenine dihydrolipoyl (5Z)-dodec-5-enoate) phosphoglycerate hydroxymethyldihydropteridine 3-phosphate phosphate beta-lyase: small subunit phosphate [acp] hypothetical protein: diphosphate tRNA ligase: [protein]-cysteine S- dehydrogenase: Mn 2+ RS10715 Mn 2+ gln glycosylase: methyltransferase acyltransferase: protein: CN62_RS04670 a 3-oxotetradecanoyl- a (5Z)-dodec- kinase: diphosphokinase: CN62_RS04850 methyltransferase: acyltransferase: acyltransferase: (Z)-N-hydroxy-2-CN62_RS06405 CN62_RS03855 kinase: an L-leucyl- superpathway of N-acetylglucosamine, CN62_RS04220 CN62_RS08590 CTP synthetase: (7,8-dihydropterin- 7 G: CN62_RS09145 CN62_RS07245 CN62_RS03855 CN62_RS12270 gln RS09995 gln Nucleoside and Nucleotide Biosynthesis [tRNA Leu ] [acp] 5-enoyl-[acp] CN62_RS05690 N-acetylmannosamine and N- CN62_RS09855 CN62_RS106001-palmitoyl- CN62_RS072451-stearoyl- a DNA containing pyruvate (4-hydroxyphenyl) a [2-oxoglutarate an N - 1-C16:0-α,ω- a cis-delta15-3-[+ 2 isozymes] beta-ketoacyl- propanoyl 6-yl)methyl a [protein]-S- an alkylated a nucleoside Leu CN62_RS05675 dehydrogenase E2 527 a cis,cis-[+ 2 isozymes] a tRNA hypothetical acetylneuraminate degradation a guanine in DNA acyl-carrier protein 2-myristoyl acyl-carrier protein sn-glycerol an apurinic/ acetimidothioate methylguanine dicarboxyl-2- hydroxyC34:1- [acyl-carrier- 3-phospho-D-glycerate phosphate [+ 3 isozymes] diphosphate methyl-L-cysteine nucleobase 6 delta19,31-3- triphosphate superpathway of purine nucleotides de novo biosynthesis I phosphatidate 3-phosphate apyrimidinic site protein] N -lipoyl-L-lysine in 16S rRNA lysophosphatidate [acp] 2+ 2+ protein: protein] N-acetylneuraminate Co RS06575 Co UMP biosynthesis III pyrimidine deoxyribonucleotides superpathway of pyrimidine deoxyribonucleoside salvage adenine and glu oxo-C50:2-[acp] 2+ 2+ CN62_RS03855 phosphoglycerate acetate kinase: N-acetylneuraminate Mg RS11215 Mg biosynthesis from CTP adenosine salvage I synthase II: [+ 2 isozymes] mutase: CN62_RS12725 lyase: PRPP 2'-deoxycytidine a (7Z)-3-CN62_RS05410 4 an O - a 1-acyl-sn 1402 1-myristoyl- a cis,cis- gln hydrogencarbonate CTP valine-- a (3R)-3- CN62_RS10740 CN62_RS10845 a cytidine a [protein]- β Cell Structure Biosynthesis val oxotetradec- N-acetyl-β-neuraminate a [protein]- an acyl-[acyl- sn-glycerol MEP CTP a cis-delta13-3- glycine glycine amidophosphoribosyltransferase: peptidoglycan biosynthesis V ( -lactam resistance) hydroxytetradecanoyl- propanoate methylthymine -glycerol 3- a palmitoyl-[acp] L-djenkolate in 16S rRNA sn-glycerol delta17,29-3- L-tyrosine RS11675 adenosine tRNA ligase: 7-enoyl-[acp] N-acetylneuraminate L-cysteine carrier protein] 3-phosphate GTP H O oxo-C32:1-[acp] Mg 2+ RS04270 Mg 2+ cytidine deaminase: N-acetylneuraminate in DNA phosphate 2 ribosomal RNA 3-phosphate hydroxyC48:2- betaine betaine CN62_RS0103365 carbamoyl- purine-nucleoside CN62_RS05960 [acp] 3-oxoacyl-[acyl- 2-phospho-D-glycerate methylated-DNA-- 1-acyl-sn-glycerol- glycerol-3- 2-C-methyl-D- cystathionine 1-acyl-sn-glycerol- hypothetical tyrosine CN62_RS06695 UDP-N-acetyl- an L-valyl- lyase: lyase: CN62_RS09365 GTPase HflX: (3R)-3- Detoxification erythritol 4-phosphate beta-lyase: small subunit 3-phosphate [acp] hypothetical protein: protein kinase: amidophosphoribosyltransferase: phosphate phosphorylase: α-D-glucosamine [tRNA Val ] carrier-protein] CN62_RS09365 [protein]-cysteine S- 3-phosphate phosphate CN62_RS06400 CDP [+ 2 isozymes] dCMP enolase: N-acetyl-D- N-acetylneuraminate methyltransferase protein: CN62_RS03620 synthase: CN62_RS07170 a tRNA Val hydroxymyristoyl- reductase: methyltransferase: acyltransferase: acyltransferase: cytidylyltransferase: CN62_RS06405 acyltransferase: CN62_RS03855 CN62_RS05060 UDP-N-acetylglucosamine [+ 3 isozymes] a metal a metal CN62_RS08480 mannosamine lyase: CN62_RS10845 S-(sulfanylmethyl) 4 H: CN62_RS05000 CN62_RS03855 a [protein]- 2+ 2+ β CDP reductase: cytidylate kinase: [acyl-carrier oxidized GTP and CN62_RS10600 CN62_RS07245 CN62_RS09080 CN62_RS10600 [+ 2 isozymes] RS10275 Cu RS13775 Cu 5-phospho- - gly CN62_RS09100 purine-nucleoside CN62_RS05405 CN62_RS09855 a 1,2-diacyl- 1-palmitoyl- 4-(cytidine 5'- pyruvate + an N - 1,2-dimyristoyl- a cis-delta13-3- 2'-deoxyuridine 1-carboxyvinyltransferase: reactive oxygen a [protein]-S- -L-cysteine phosphate GDP H a cis,cis- L-tyrosine cation cation CN62_RS09105 CN62_RS08670 CN62_RS10510 protein] dGTP detoxification arsenate pyruvate N-acetyl-β-D-mannosamine a thymine in DNA diphospho)-2-C- methylcytidine 1402 sn-glycerol [+ 2 isozymes] D-ribosylamine phosphorylase: CN62_RS08250 [+ 2 isozymes] phosphoenolpyruvate species degradation acyl-carrier protein sn-glycerol acyl-carrier protein sn-glycerol hydroxyC32:1- dehydratase: detoxification methyl-L-cysteine delta17,29-3- phosphate dCDP thymidine kinase: dCDP CN62_RS07150 a (3R,7Z)-3- 3-phosphate 3-phosphate methyl-D-erythritol in 16S rRNA 3-phosphate [acp] carbamoyl UDP-N-acetylglucosamine CN62_RS05420 II (glutaredoxin) N-acetyl-D- oxo-C48:2-[acp] phosphoribosylamine- asp adenine hydroxytetradec- phosphate CN62_RS08020 1-carboxyvinyltransferase: alanine-- pyruvate kinase: dGTP GTP superoxide a metal a metal + + -glycine ligase: nucleoside- ala 7-enoyl-[acp] mannosamine RS11660 Na RS06720 Na nucleoside- tRNA ligase: a (2E)-tetradec- CN62_RS07495 arsenate cation cation thymidine CN62_RS12305 ∆ 7 CN62_RS03645 diphosphate kinase: 3-hydroxy cis superoxide 6-phosphate 1915 1-palmitoyl- a cis,cis- diphosphate dUMP adenine CN62_RS09550 2-enoyl-[acp] arsenate a pseudouridine an insertion sequence (11Z,14Z,17Z)-3- D-ribose 5- aspartate CN62_RS12270 UDP-N-acetyl-α- an L-alanyl- N-acetylmannosamine- β-D-fructofuranose 1-phosphate a guanine 34 in tRNA queuine sn-glycerol an apo-[aryl- a cis-delta11-3- phosphoribosyltransferase: -tetradecenoyl- pyruvate dismutase [Mn]: reductase: a myristoyl-[acp] H O diphosphate coenzyme A sn-glycerol delta15,27-3- phosphate kinase: dCMP D-glucosamine- [tRNA Ala ] myristoyl-[acyl- in 23S rRNA 3-phosphate 2 carrier protein] element IS30 oxoicosatrienoyl-CoA oxo-C30:1-[acp] carbamoyltransferase: thymidylate [acp] 8-oxo-dGTP 8-oxo-GTP CN62_RS06850 6-phosphate fructose-bisphosphate tRNA guanosine(34) 23S rRNA 3-oxoacyl-[acyl- 3-phosphate hydroxyC46:2- ribose-5- CN62_RS12270 thymidine kinase: dCTP CN62_RS10400 Ala CN62_RS04350 glycerol-3- manganese- holo-ACP transposase: 1-acyl-sn-glycerol- hypothetical a metal a metal GAR CN62_RS09110 enolpyruvate a tRNA carrier-protein] 2-epimerase: RS04175 sulfate RS03555 sulfate deoxycytidylate synthase: dehydratase: hydrogen arsenite aldolase: CN62_RS04660 transglycosylase (pseudouridine(1915)- dependent inorganic carrier-protein] [acp] hypothetical protein: phosphate CN62_RS08020 reductase: 8-oxo-dGTP phosphate synthase: CN62_RS0103190 3-phosphate cation cation deaminase: CN62_RS06385 UDP-N- CN62_RS05420 CN62_RS10885 fructose-bisphosphate Tgt: CN62_RS12805 N(3))-methyltransferase reductase: protein: isomerase: phosphoribosylglycinamide dCTP AMP peroxide acyltransferase: pyrophosphatase: CN62_RS10950 [+ 9 isozymes] acyltransferase: CN62_RS03855 acetylenolpyruvoylglucosamine CN62_RS05395 a (2E,7Z)- diphosphatase: [+ 2 isozymes] formyltransferase: N-carbamoyl- CN62_RS06745 hypothetical protein: aldolase: CN62_RS06115 3 RlmH: CN62_RS13820 CN62_RS10165 a holo-[aryl- an insertion CN62_RS05405 CN62_RS10600 CN62_RS03855 CN62_RS07135 CN62_RS08620 34 an N - CN62_RS072451-myristoyl- 3',5'-ADP (3R,11Z,14Z,17Z)-3- 1-palmitoyl- a cis-delta11-3-[+ 2 isozymes] D-ribulose reductase: CN62_RS09555 tetradeca-2,7- N-acetyl-D- guanine a queuosine in tRNA carrier protein] sequence IS30 with CN62_RS03630 L-aspartate dUMP CN62_RS13955 a myristoyl-[acp] D-glyceraldehyde DHAP methylpseudouridine 1915 phosphate H + hydroxyicosatrienoyl- 2-myristoyl a cis,cis-[+ 2 isozymes] nitrite nitrite dienoyl-[acp] 8-oxo-dGTP 8-oxo-GMP glucosamine acyl-carrier protein sn-glycerol hydroxyC30:1- 5-phosphate RS08825 a sugar RS11375 a sugar UDP-N- asparagine-- integrated transposon delta15,27-3- formate formate asn in 23S rRNA 3-phosphate CoA phosphatidate [acp] FGAR dihydroorotase: thymidylate acetylenolpyruvoylglucosamine tRNA ligase: diphosphatase: arsenite 6-phosphate 3-oxoacyl-[acyl- oxo-C46:2-[acp] CN62_RS08615 synthase: reductase: CN62_RS09580 CN62_RS10205 CN62_RS08910 O H O hydroxyl radical N-acetylglucosamine- an L-asparaginyl- carrier-protein] 2 2 phosphoribosylformylglycinamidine CN62_RS06385 xanthine and Asn 6-phosphate dTMP ala UDP-N-acetyl- [tRNA ] (S)-dihydroorotate xanthosine salvage reductase: a (7Z)-tetradec- 8-oxo-dGMP (R)-4'- 34 N-acetyl-D- α-D- 37 1-palmitoyl- a cis,cis- a (9Z)-3- sulfite RS11415 sulfite synthase: CN62_RS03615 hypothetical α-D-muramate tRNA Asn deacetylase: a 5-carboxymethylaminomethyluridine a single a ribonucleoside a peptidoglycan adenine a D-hexose CN62_RS05405 phosphopantothenoyl- galactosamine [EntB aryl- sn-glycerol thymidylate kinase: 7-enoyl-[acp] CN62_RS12795 in tRNA Leu glucopyranose UTP coenzyme A in tRNA val delta13,25-3- oxooctacos- protein: stranded DNA triphosphate carrier protein] 1 L-cysteine tRNA (cytidine(34) 6-phosphate peptidoglycan tRNA1(Val) 3-phosphate hydroxyC44:2- 9-enoyl-[acp] FGAM dihydroorotate CN62_RS07670 UDP-N- glu beta-ketoacyl- D-glucosamine N-acetylglucosamine- DNA primase: 1-phosphate holo-ACP 1-acyl-sn-glycerol- hypothetical CN62_RS13955 xanthosine beta-ketoacyl- Carbohydrate Degradation UTP--glucose- GlcNAc glucokinase: dehydrogenase [acyl-carrier- phosphopantothenoylcysteine -2'-O)- (adenine(37)-N6)- [acp] hypothetical protein: dTDP acetylmuramate-- [acyl-carrier- 6-phosphate 6-phosphate CN62_RS04325 1-phosphate synthase: 3-phosphate CN62_RS06380 V-type ATP dTMP methyltransferase: deacetylase: methyltransferase: protein: + + phosphoribosylformylglycinamidine electron purine-nucleoside L-alanine ligase: glutamate protein] decarboxylase: CN62_RS08890 deacetylase: DNA primase: CN62_RS10950 acyltransferase: CN62_RS03855 H H protein] uridylyltransferase: CN62_RS09930 synthase cyclo-ligase: CN62_RS03625 transfer subunit: nucleoside- phosphorylase: aspartate-- synthase II: D-galactose degradation I (Leloir pathway) CN62_RS05645 a holo-[EntB aryl- 6 CN62_RS10175 CN62_RS03855 thymidylate CN62_RS10100 racemase: asp synthase II: CN62_RS12795 CN62_RS08205 3',5'-ADP an N - 1-palmitoyl-2-CN62_RS10600 a cis-delta9-3-[+ 2 isozymes] D-hexose 6- diphosphate kinase: tRNA ligase: lactose and galactose a 5-carboxymethylaminomethyl- D-galactosamine CN62_RS13120 a deacetylated CN62_RS0102815 CN62_RS07150 CN62_RS05410 4'-phosphopantetheine ssDNA/pppN(pN) carrier protein] acetate 37 a cis,cis-[+ 2 isozymes] kinase: CN62_RS11770 CN62_RS05410 34 Leu acetate UDP-α-D-glucose methyladenine cis-vaccenoyl hydroxyC28:1- phosphate AIR CN62_RS12270 CN62_RS13235 degradation I α-D-glucosamine 2'-O-methyluridine in tRNA 6-phosphate peptidoglycan PRPP UDP-N-acetyl- an L-aspartyl- β-D-galactopyranose hybrid val delta13,25-3- CN62_RS07670 purine-nucleoside n -1 in tRNA phosphatidate [acp] F0F1 ATP orotate asp a 3-oxohexadecanoyl- 3-oxoacyl-[acyl- lactose 6'- 6-phosphate 1 + + dTTP phosphorylase: α-D-muramoyl- D-glt [tRNA ] oxo-C44:2-[acp] H H 5-(carboxyamino) dTDP tRNA asp [acp] carrier-protein] galactose synthase CN62_RS07170 L-alanine phosphate glucosamine- imidazole orotate mutarotase: 6-phospho-beta- xanthine hypothetical reductase: 6-phosphate ribonucleotide phosphoribosyltransferase: nucleoside- CN62_RS03710 galactosidase: a 7,8-dihydro-8- (5Z,8Z,11Z,14Z,17Z)-3- a cytidine 34 a uracil 1498 a cis,cis- a (1->4)- UDP-N- protein: CN62_RS05405 CTP phosphocholine [EntF L-seryl- α-amylose diphosphate xanthine CN62_RS08685 deaminase: coenzyme A L-cystathionine delta11,23-3- α-D-glucan mutase: CN62_RS06485 a (9Z)-3- a tRNA precursor CTP ATP oxoguanine in DNA 4'-phosphopantetheine ATP oxodocosapentaenoyl-CoA in tRNA in 16S rRNA acetylmuramoyl- CN62_RS03855 α-D-galactopyranose CN62_RS09690 carrier protein] 1,4-alpha-glucan 1,4-alpha-glucan CN62_RS03650 kinase: phosphoribosyltransferase: oxohexadec- 6-phospho-beta- DNA- phosphorylcholine 3-oxoacyl-[acyl- holo-ACP cystathionine tRNA (cytidine(34) 16S rRNA hydroxyC42:2- pyrimidine deoxyribonucleotides de novo biosynthesis I L-alanine--D- tyrosine-- [+ 2 isozymes] CCA tRNA branching branching CN62_RS12270 CN62_RS11605 9-enoyl-[acp] galactosidase: formamidopyrimidine phosphopantetheine transferase LicD: carrier-protein] synthase: beta-lyase: -2'-O)- (uracil(1498)-N(3))- [acp] hypothetical asp orotidine 5'- glutamate ligase: tyr a (3R)-3- F6P CAIR tRNA ligase: galactokinase: nucleotidyltransferase: glycosylase: adenylyltransferase: CN62_RS09090 reductase: methyltransferase: methyltransferase: protein: protein GlgB: protein GlgB: phosphate dTTP UDP CTP hypothetical CN62_RS08710 a holoCN62_RS10950-[EntF CN62_RS06405 CN62_RS06465 CN62_RS13165 hydroxyhexadecanoyl- CN62_RS11640 D-galactopyranose a tRNA CN62_RS10285 CN62_RS08440 CN62_RS08440 an L-tyrosyl- protein: CN62_RS07795 CN62_RS12320 [+ 2 isozymes] CN62_RS05405 CN62_RS05645 3 CN62_RS11275 CN62_RS03855 XMP [acp] 3'-dephospho- 3',5'-ADP L-seryl-carrier pyruvate L-homocysteine a 2'-O- an N - a (1,6)-α-D- inosine-5'-phosphate biosynthesis I Tyr 6-phosphate containing a an apurinic site 7,8-dihydro- (3R,5Z,8Z,11Z,14Z,17Z)-3- orotidine-5'- [tRNA ] CN62_RS03855 34 1498 a cis,cis-[+ 2 isozymes] amylopectin phosphoribosylaminoimidazolesuccinocarboxamide UDP-N-acetyl- (3R)-3- α-D-galactose CoA CDP-choline protein] methylcytidine methyluracil glucosyl-(1,4) phosphate a tRNA Tyr UDP-α-D-glucose galactose-6- 3' CCA end within DNA 8-oxoguanine hydroxydocosapentaenoyl-CoA delta11,23-3- synthase: CN62_RS03605 dUDP CDP lys α-D-muramoyl-L- hydroxypalmitoyl- [+ 2 isozymes] 1-phosphate in tRNA in 16S rRNA -α-glucan decarboxylase: AIR a (3R,9Z)-3- phosphate oxo-C42:2-[acp] nucleoside-diphosphate CDP reductase: alanyl-D-glutamate [acyl-carrier CN62_RS06480 hydroxyhexadec- isomerase: kinase: CN62_RS12270 CN62_RS08670 protein] SAICAR 5-(carboxyamino) 9-enoyl-[acp] CN62_RS08725 UMP UDP-N- dehydratase: ManNAc-GlcNAc- UDP-N-acetylmuramoyl-L- 3 S-(4-oxo-2- a uridine 38- a (1->4)- imidazole ribonucleotide dUTP dCDP 3-hydroxy cis ∆ 9 CN62_RS08730 a Xaa-Pro dipeptidyl- an N -methyladenine a D-aminoacyl- sn-glycerol adenylosuccinate acetylmuramoyl- tryptophan-- CDP-glycerol γ phosphoenol formate CTP α-D-glucan synthase: CN62_RS03655 a tRNA Trp CN62_RS05420 PP-undecaprenol alanyl- -D-glutamyl-meso-2,6- in DNA VibB coenzyme A methylpentan- dGDP 40 in tRNA 3-phosphate -hexadecenoyl- D-tagatofuranose peptidase substrate [tRNA] 1,4-alpha-glucan lyase: deoxyuridine nucleoside-diphosphate L-alanyl-D- tRNA ligase: CDP-glycerol-- diaminopimeloyl-D-alanine DNA-3- 2-yl)-L-cysteine pyruvate RluA family glycerol-3- a (2E)-hexadec- [acp] 6-phosphate LD- Xaa-Pro dipeptidyl- D-aminoacyl- holo-ACP cystathionine anaerobic CN62_RS03665 N5-CAIR 5'-triphosphate kinase: CN62_RS12270 glutamate--L- CN62_RS13765 an L-tryptophanyl- glycerophosphate methyladenine pyruvate kinase: pseudouridine branching D-ala carboxypeptidase: peptidase: tRNA deacylase: synthase: beta-lyase: ribonucleoside- phosphate Trp 2-enoyl-[acp] dehydratase: tagatose-6- protein GlgB: nucleotidohydrolase: dCTP lysine ligase: [tRNA ] glycerophosphotransferase: glycosylase I: CN62_RS07495 synthase: acyltransferase: 5-(carboxyamino) CN62_RS05420 UDP-N-acetyl-α-D-muramoyl-CN62_RS04260 CN62_RS07480 CN62_RS10680 CN62_RS10950 4-methyl-4-CN62_RS06405 triphosphate AICAR CN62_RS03495 CN62_RS10145 palmitoyl-[acyl- phosphate CN62_RS05090 a dipeptide with a CN62_RS04250 an uncharged a holo-[VibB aryl- CN62_RS07645 CN62_RS08440 superpathway of guanosine trp a (2E,9Z)- γ reductase: 1-oleoyl-snCN62_RS07245 imidazole ribonucleotide D-alanine--D- kinase: Gro-P-ManNAc-GlcNAc- L-alanyl- -D-glutamyl- D-ala a peptide an apurinic site a D-amino acid 3',5'-ADP pyruvate sulfanylpentan- dGTP pyruvate nucleotides de novo biosynthesis I nucleoside-triphosphate carrier-protein] CMP C-terminal L-proline 3-methyladenine tRNA carrier protein] CN62_RS04400 [+ 3 isozymes] starch bifunctional mutase: CN62_RS03650 alanine ligase: hexadeca-2,9- PP-undecaprenol meso-2,6-diaminopimelate 2-one 38- -glycerol 3- UDP-N-acetyl- reductase: CN62_RS08720 within DNA a pseudouridine phosphoribosylaminoimidazolecarboxamide diphosphatase: dienoyl-[acp] dCTP phosphate guanine and α-D-muramoyl- CN62_RS10820 40 in tRNA asp CN62_RS11765 CN62_RS05395 D-tagatofuranose formyltransferase/IMP CAIR guanosine salvage IMP L-alanyl-γ-D- 1,6-bisphosphate cyclohydrolase PurH: CN62_RS03640 D-alanyl-D-alanine threonine-- UDP-glucose dUMP glutamyl-L-lysine thr a palmitoyl-[acp] tRNA ligase: UDP-glucose:α- 4-epimerase: tagatose- a (1->4)- phosphoribosylaminoimidazolesuccinocarboxamide a single- (R)-5- a nucleoside FAICAR IMP thymidylate synthase: CN62_RS11705 bisphosphate sucrose O-succinyl-L- AsbD acyl- formate UTP a 3-oxopimeloyl- guanosine CN62_RS10630 an L-threonyl- D-galactose- O-acetyl-L-serine hydrogen selenide stranded RNA phosphomevalonate coenzyme A a type IV prepilin phosphoenol α-D-glucan dehydrogenase: synthase: CN62_RS03605 CN62_RS06385 UDP-N- acyl-ACP a palmitoleoyl-[acp] sucrose homoserine carrier protein dADP [acp] methyl ester triphosphate purine-nucleoside Thr 1-phosphate UDP-glucose 4- aldolase: polyribonucleotide pyruvate 1,4-alpha-glucan bifunctional CN62_RS13760 acetylmuramoyl- [tRNA ] thioesterase: O-acetylhomoserine cystathionine holo-ACP prepilin anaerobic hypothetical nucleoside- hypothetical protein: phosphorylase: a tRNA Thr uridylyltransferase: epimerase GalE: CN62_RS08715 nucleotidyltransferase: phosphorylase: phosphomevalonate pyruvate kinase: branching phosphoribosylaminoimidazolecarboxamide tripeptide-- CN62_RS09655 acyl-ACP aminocarboxypropyltransferase/ gamma-synthase: synthase: peptidase: ribonucleoside- protein: triphosphate SAICAR CN62_RS13955 CN62_RS07170 CN62_RS11635 CN62_RS10525 D-glyceraldehyde CN62_RS06050 CN62_RS11835 kinase: CN62_RS05215 CN62_RS07495 protein GlgB: formyltransferase/IMP D-alanyl-D- thioesterase: α-D-glucopyranose cysteine synthase: CN62_RS08820 α-D- CN62_RS10120 CN62_RS10950 CN62_RS11465 triphosphate CN62_RS03855 diphosphatase: XMP UDP-α-D-galactose DHAP a nucleoside a single- CN62_RS08440 dTMP purine-nucleoside palmitate 1-phosphate 3-phosphate a holo-[AsbD acyl- a cleaved type reductase: CN62_RS11765 cyclohydrolase PurH: CN62_RS03640 alanine ligase: CN62_RS09655 acetate L-selenocysteine glucopyranose β-D-fructofuranose (R)-mevalonate succinate L-homocysteine 3',5'-ADP a peptide dATP pyruvate a (3R)-3-[+ 2 isozymes] adenylosuccinate superpathway of diphosphate stranded RNA carrier protein] IV prepilin a nucleoside 5'- a glycogen phosphorylase: CN62_RS10815 1-phosphate diphosphate CN62_RS04400 xanthosine-5'- lyase: CN62_RS03665 thymidylate kinase: hydroxypimeloyl- adenosine nucleotides CN62_RS07150 palmitoleate dUTP monophosphate CN62_RS07670 serine-- [acp] methyl ester IMP phosphate:L- de novo biosynthesis I guanine ser UDP-N-acetyl- tRNA ligase: glutamine AICAR dTDP D-glucopyranose D-arabinose degradation I α-D-muramoyl- CN62_RS05360 an L-seryl- fucose degradation amido-ligase IMP asp xanthine palmitoyl-CoA 6-phosphate Man GlcNAc - an N-terminal- 1-oleoyl-sn a protein-L- bifunctional nucleoside-diphosphate L-alanyl-γ-D- ser isoprimeverose 8 2 a D-tryptophanyl- a 3-oxoicosanoyl- + (AMP-forming): [tRNA ] O-acetyl-L- carboxynorspermidine O-succinyl-L- an acyl phosphate -glycerol 3- methionine- NAD phosphoribosyltransferase: D-arabinopyranose methanethiol [protein] (isomer methanethiol L-methionyl-L- Trp IMP phosphoribosylaminoimidazolecarboxamide adenylosuccinate kinase: CN62_RS12270 glutamyl-L-lysyl- a tRNA ser β-L-fucopyranose homoserine homoserine [tRNA ] [acp] CN62_RS09770 CN62_RS11605 8A B ) seryl-[protein] phosphate (R)-S-oxide formyltransferase/IMP O-acetylhomoserine 1,2,3 alpha-1,2-2,3 carboxynorspermidine cystathionine methionine D-aminoacyl- 1-acyl-sn-glycerol- hypothetical peptide- dehydrogenase: synthetase: dTTP D-alanyl-D-alanine L-fucose alpha-xylosidase: NAD(+) kinase: mannosidase: acylphosphatase: protein: CN62_RS13760 cyclohydrolase PurH: CN62_RS03640 CN62_RS03425 hypoxanthine aminocarboxypropyltransferase/ CN62_RS04905 decarboxylase: gamma-synthase: aminopeptidase: tRNA deacylase: 3-phosphate methionine (R)-S- GMP adenylo-succinate isomerase: CN62_RS12345 CN62_RS08340 phosphoribosyltransferase: α cysteine synthase: CN62_RS08820 CN62_RS13390Man GlcNAc - CN62_RS07605 CN62_RS10120 CN62_RS08265 CN62_RS10680 acyltransferase: CN62_RS03855 oxide reductase: CN62_RS13450 -L-fucopyranose β-D- 7 2 FAICAR an N-terminal Trp CN62_RS13890 acetate met α-D-xylopyranose D-glucopyranose [protein] (isomer succinate met met a tRNA D-tryptophan CN62_RS10600 a (3R)-3-[+ 2 isozymes] CN62_RS06340 + adenylosuccinate UDP-N-acetyl- proline-- mannopyranose norspermidine L-seryl-[protein] a carboxylate dioleoyl a [protein]-L- NADP guanylate kinase: pro Carbohydrate Biosynthesis D-ribulose L-fucose 7A B ) hydroxyicosanoyl- bifunctional lyase: α-D-muramoyl- peptidoglycan biosynthesis I tRNA ligase: 1,2,3 2 phosphatidate methionine XMP CN62_RS11155 GMP isomerase: [acp] phosphoribosylaminoimidazolecarboxamide CN62_RS03665 L-alanyl-γ-D- (meso-diaminopimelate containing) CN62_RS04715 an L-prolyl- UDP-N-acetyl-D- CN62_RS13450 formyltransferase/IMP glutamyl-L- UDP-N-acetyl- Pro dTDP-L-rhamnose PRPP biosynthesis xanthosine-5'- [tRNA ] glucosamine biosynthesis I GDP cyclohydrolase PurH: CN62_RS03640 AMP lysyl-D-alanine α-D-glucosamine a tRNA Pro biosynthesis L-fuculose Man GlcNAc - Man GlcNAc - an N-terminal- phosphate:L- D-ribulose core 1 7 2 7 2 an apo [peptidyl- a D-aspartyl- a D-tyrosyl- chitin a 3-oxoglutaryl- roseoflavin pullulan superpathway of 5-aminoimidazole UDP-N-acetylglucosamine D-glucopyranose D-ribose 5- nicotinate PRPP protein (isomer [protein] (isomer coenzyme A L-methionyl-L- glutamine α-D- 1-phosphate L-fuculokinase: carrier protein] [tRNA asp ] [tRNA Tyr ] [acp] methyl ester asp ribonucleotide biosynthesis 1-carboxyvinyltransferase: 6-phosphate phosphate endo-alpha-N- nicotinate 7A B ) 7A B ) valyl-[protein] peptidoglycan bifunctional IMP glucopyranose ribose-phosphate 1,2,3 alpha-1,2-1 1,2,3 alpha-1,2-3 holo-ACP methionine D-aminoacyl- D-aminoacyl- hypothetical amido-ligase adenylate kinase: glucose-6- CN62_RS13490 acetylgalactosaminidase: GlcNAc pullulanase: CN62_RS08250 phosphoribosyltransferase: mannosidase: mannosidase: protein: riboflavin kinase/ (AMP-forming): nucleoside- GDP reductase: undecaprenyl- phosphate 1-phosphate pyrophosphokinase synthase: aminopeptidase: tRNA deacylase: tRNA deacylase: CN62_RS04735 CN62_RS04535 PRPP guanine and glucose-1-phosphate L-fuculose CN62_RS05140 CN62_RS09715 deacetylase: FAD synthetase: CN62_RS09770 adenylosuccinate diphosphate CN62_RS08670 diphospho-N- UDP-N-acetylglucosamine phenylalanine- isomerase: pgi 2: CN62_RS08325 a [glycoprotein]- β-D-galactosyl- CN62_RS13390Man GlcNAc - CN62_RS13390Man GlcNAc CN62_RS10950 CN62_RS08265 CN62_RS10680 CN62_RS10680 CN62_RS03855 amidophosphoribosyltransferase: guanosine salvage II thymidylyltransferase: 1-phosphate β-D- 6 2 β-D- 6 2 a holo [peptidyl- an N-terminal CN62_RS09930 CN62_RS08385 synthetase: 1-carboxyvinyltransferase: -tRNA ligase: NaMN asp Tyr kinase: acetylmuramoyl- F6P CN62_RS05110 [+ 2 isozymes] (L-serine/L- (1->3)-N-acetyl- [protein] (isomer -[protein] 3',5'-ADP met tRNA D-aspartate a tRNA D-tyrosine a (3R)-3-[+ 2 isozymes] maltotriose CN62_RS0103365 phe α glycolaldehyde fuculose mannopyranose mannopyranose carrier protein] L-valyl-[protein] roseoflavin CN62_RS03425 CN62_RS12270 ADP L-alanyl-γ-D- CN62_RS12305 CN62_RS06005 dTDP- -D-glucose PRPP DHAP threonine) D-galactosamine 6A B ) (isomer 6A ) acetate chitosan GMP 1,2 1 1,2,3 hydroxyglutaryl- 5'-phosphate amidophosphoribosyltransferase: glutamine-- phosphate dGDP guanosine glutamyl-L- UDP-N-acetyl-α- CN62_RS06015 an L-phenylalanyl- dTDP-glucose [acp] methyl ester adenylo-succinate CN62_RS03620 glycolaldehyde superpathway of pyrimidine 5-phospho-β- D-glucosamine- Phe fructose-6- aldolase: ADP reductase: lysyl- D-alanineundecaprenyldiphospho- [tRNA ] 4,6-dehydratase: dehydrogenase: guanylate kinase: nucleobases salvage D-ribosylamine enolpyruvate a tRNA Phe phosphate CN62_RS13485 adenylosuccinate GTP nucleoside- CN62_RS08670 muramoylpentapeptide beta-N- CN62_RS05120 CN62_RS08435 CN62_RS11155 transaminase a 2-acetyl-1-alkyl- D-sedoheptulose D-glyceraldehyde Man GlcNAc - Man GlcNAc - an N-terminal- γ-L-glutamyl-[(S a (7Z)-3- CTP diphosphate phosphoribosylamine- UDP-N- 8 2 9 2 an N-modified lyase: uracil acetylglucosaminyltransferase: dTDP-4-dehydro- (S)-lactaldehyde DHAP sn-glycero-3- [protein] (isomer [protein] (isomer L-methionyl-L- a cytosine in DNA a uridine in tRNA oxohexacos- thr guanine (isomerizing): chitobiose degradation 7-phosphate 3-phosphate )-allyl]-L-cysteine nucleoside- CN62_RS03665 kinase: uracil -glycine ligase: CN62_RS06470 acetylenolpyruvoylglucosamine 6-deoxy-α-D- glycolate aminoacyl-[tRNA] glutamyl ditrans,octacis- CN62_RS04725 phosphocholine1-alkyl-2- transketolase: 8A Balpha-1,2-) 9A Balpha-1,2-) peptidyl-tRNA alanyl-[protein]methionine DNA cytosine tRNA 7-enoyl-[acp]hypothetical CN62_RS12270 dADP CN62_RS03645 reductase: CN62_RS09555 1,2,3 1,2 1,2,3 1,2,3 triphosphate GDP phosphoribosyltransferase: undecaprenyldiphospho- glucopyranose N,N'- CN62_RS13305 aminopeptidase: dihydrouridine threonine xanthine D-glucosamine acetylglycerophosphocholine mannosidase: mannosidase: : aminopeptidase: methyltransferase: protein: diphosphatase: CN62_RS06750 UDP-N- methionine-- CN62_RS11700 dehydratase: AMP GAR N-acetyl-(N- met dTDP-4- diacetylchitobiose : CN62_RS09795 [+ 3 isozymes] CN62_RS13390 CN62_RS13390 CN62_RS13855 CN62_RS08265 CN62_RS05965 synthase DusB: CN62_RS03855 dGTP nucleoside- phosphoribosyltransferase: 6-phosphate a 1-alkyl-2-lyso- D-xylulose D-ribose 5- Man GlcNAc - Man GlcNAc CN62_RS11765 bifunctional pyrimidine acetylglucosaminyl) acetylenolpyruvoylglucosamine tRNA ligase: dehydrorhamnose 6'-phosphate β-D- 7 2 β-D- 5 2 an N-modified an uncharged an N-terminal L- CN62_RS13585 CN62_RS05530 diphosphate CN62_RS11605 an L-methionyl- sucrose degradation III (sucrose invertase) sn-glycero-3- acetate 5-phosphate phosphate [protein] (isomer -[protein] met S-allyl-L-cysteine glu a 5-methylcytosine a (3R,7Z)-3-[+ 2 isozymes] CMP operon transcriptional phosphoribosylglycinamide muramoyl-L-alanyl-γ-D- reductase: CN62_RS09580 CN62_RS06960 phosphoglucosamine 3,5-epimerase: UDP-α-D-glucuronate mannopyranose mannopyranose amino acid tRNA alanyl-[protein] a 5,6-dihydrouridine 2-oxobutanoate kinase: hypoxanthine [elongator N-monoacetylchitobiose phosphocholine 7A B ) (isomer 5A ) in DNA hydroxyhexacos- adenylate kinase: regulator/uracil formyltransferase: glutamyl-L-lysyl-D-alanine ala UDP-N-acetyl- mutase: CN62_RS10305 CN62_RS05115 biosynthesis (from 1,2 1,2 1,2 in tRNA elongator Met CN62_RS04535 CN62_RS12270 phosphoribosyltransferase: α tRNA ] 6'-phosphate 7-enoyl-[acp] GDP reductase: phosphoribosyltransferase: CN62_RS03630 -D-muramate Met α-D-glucosamine dTDP-4-dehydro- UDP-glucose) sucrose nucleoside- tRNA CN62_RS13890 6-phospho-beta- CN62_RS08670 CN62_RS09115 1-phosphate β-L-rhamnose UDP-α-D-glucose diphosphate dATP FGAR UDP-N- glu UMP dTDP-4- UDP-glucose 6- glucosidase: beta- L-alanyl-γ-D-glutamyl-meso- Man GlcNAc - Man GlcNAc - an apo-[LYS2 L- an N-terminal- a (5Z)-3- a glucosylated dTTP kinase: ADP bifunctional N- 2503 7 2 8 2 pyrimidine GMP ditrans,octacis- acetylmuramate-- adenine in 23S rRNA L-selenocystathionine Ala dehydrorhamnose dehydrogenase: CN62_RS06710 fructofuranosidase: 2,6-diaminopimeloyl-D-alanine [protein] (isomer [protein] (isomer 2-aminoadipyl- coenzyme A L-methionyl- L-saccharopine a glycyl-[tRNA ] oxotetracos- glycogenin CN62_RS12270 ribonucleosides salvage I UMP kinase: phosphoribosylformylglycinamidine undecaprenyldiphospho- glutamate acetylglucosamine- nucleoside- L-alanine ligase: N-acetyl-D- 23S rRNA (adenine(2503) LD-carboxypeptidase: 7A B ) 8A B ) carrier-protein] glycyl-[protein] cystathionine 5-enoyl-[acp] 1,4-alpha-glucan lysine-- 1-phosphate reductase: CN62_RS14090 CN62_RS11360 1,2 1,2alpha-1,2- 1,2,3 alpha-1,2-1,3 holo-ACP methionine saccharopine D-aminoacyl- hypothetical CN62_RS07695 synthase: CN62_RS03615 N-acetyl-(N- racemase: Lys UDP-α-D- triphosphate ADP reductase: cytidine CN62_RS10100 a tRNA glucosamine D-glucosamine -C(2))-methyltransferase CN62_RS04260 beta-lyase: branching tRNA ligase: uridyltransferase/ CN62_RS05125 mannosidase: mannosidase: synthase: aminopeptidase: dehydrogenase: tRNA deacylase: protein: diphosphatase: CN62_RS08670 cytidylate kinase: CMP acetylglucosaminyl) CN62_RS11770 glucuronate 6-phosphate RlmN: CN62_RS06860 γ CN62_RS06405 protein GlgB: dGDP FGAM CN62_RS06545 glucosamine- dTDP-β-L- β L-alanyl- -D-glutamyl- CN62_RS13390Man GlcNAc - CN62_RS13390Man GlcNAc CN62_RS10950 CN62_RS08265 CN62_RS0102800 CN62_RS10680 CN62_RS03855 CN62_RS10510 phosphorylation muramoyl-L-alanyl- UDP-N-acetyl- an L-lysyl- -D-fructofuranose D-glucopyranose D-ala β 6 2 β 5 2 a holo-[LYS2 L- CN62_RS11765 2503 -D- -D- an N-terminal seleno-L- CN62_RS08440 cytidine Lys rhamnose a 2-methyladenine in 23S rRNA 5'-deoxyadenosine met meso-diaminopimelate pyruvate Ala [+ 2 isozymes] γ-D-isoglutaminyl- α-D-muramoyl- D-glt [tRNA ] 1-phosphate [protein] (isomer -[protein] 2-aminoadipyl- 3',5'-ADP met allysine glu a tRNA gly a (3R,5Z)-3- dTMP deaminase: UDP CMP mannopyranose mannopyranose glycyl-[protein] homocysteine a glycogen dADP phosphoribosylformylglycinamidine lys acetyltransferase: glucokinase: 6A B ) (isomer 5A ) carrier-protein] hydroxytetracos- GTP L-lysyl-D-alanine L-alanine 1,2 2 1,2 CN62_RS06695 CMP cytidylate kinase: cyclo-ligase: CN62_RS03625 CN62_RS06380 nucleoside- nucleoside-diphosphate CN62_RS07865 trehalose degradation I (low osmolarity) fructokinase: 5-enoyl-[acp] CN62_RS10510 diphosphate nucleoside- [+ 2 isozymes] kinase: CN62_RS12270 UDP-N- N-acetyl-α-D- CN62_RS11065 D-glucopyranose CDP AIR UDP-α-D-galactofuranose kinase: diphosphate UTP acetylmuramoyl- glucosamine α,α-trehalose 6-phosphate Man GlcNAc - Man GlcNAc - GlcMan GlcNAc S-(6-hydroxy- an (11Z)-3- UTP CN62_RS12270 uridine nucleoside- ditrans,octacis- L-alanine--D- histidine-- 1-phosphate biosynthesis an N 10 - an L-methionyl- 9 2 6 2 9 2 lysine within an organic kinase: 6-phosphate glucose-6- [DNA] [protein] (isomer [protein] (isomer -[protein] 4-methylhexan- (R)-lipoate 2-phosphoglycolate (R)-mevalonate oxooctadec- CTP synthetase: undecaprenyldiphospho- Met gcv protein H hydroperoxide CN62_RS12270 uridine kinase: diphosphate glutamate ligase: tRNA ligase: formyltetrahydrofolate [initiator tRNA ] alpha-1,2- nucleoside- CN62_RS05675 bifunctional N- UDP-α-D-glucose phosphate methionyl-tRNA 9A Balpha-1,2-) 6A Balpha-1,2-) 4-yl)-L-cysteine lipoate-- 11-enoyl-[acp]hypothetical kinase: N-acetyl-(N- CN62_RS06465 CN62_RS13275 1,2,3 1,2,3 1,2 1 cystathionine phosphoglycolate mevalonate triphosphate CN62_RS08805 acetylglucosamine- alpha,alpha- isomerase: III: CN62_RS11595 mannosidase: protein ligase: thiol peroxidase: acetylglucosaminyl) UDP-glucose 4-epimerase: formyltransferase: mannosidase: mannosidase: beta-lyase: phosphatase: kinase: protein: dGTP dATP CTP CN62_RS12270 hypothetical phosphotrehalase: a 2'- CN62_RS13390 CN62_RS10720 diphosphatase: UMP 1-phosphate CN62_RS11705 pgi CN62_RS11140 CN62_RS13390 CN62_RS13390 CN62_RS14575 CN62_RS03855 muramoyl-L-alanyl-γ-D- UDP-N-acetyl- his an N-formyl- deoxyribonucleoside [DNA] Man GlcNAc - Man GlcNAc D-glucosyl- Man GlcNAc - CN62_RS06405 a [glycine-cleavage CN62_RS03860 CN62_RS05205 CN62_RS11765 CTP meso- protein: uridyltransferase/ CN62_RS11780 β-D- 8 2 β-D- 5 2 8 2 3-methyl-3- isoglutaminyl-N-(β-D- α-D-muramoyl-L- UDP-glucose 4-epimerase L-methionyl- a tetrahydrofolate 5'-monophosphate [protein] (isomer -[protein] α(1->3)- α- [protein] (isomer pyruvate complex H protein] (R)-5- a (3R,11Z)-3-[+ 2 isozymes] diaminopimelate CN62_RS13295 an L-histidyl- glucosamine- F6P mannopyranose mannopyranose sulfanylhexan-1-ol glycolate an alcohol UMP asparatyl)-L-lysyl-D-alanine alanyl-D-glutamate GalE: CN62_RS10525 [initiator tRNA met ] 8A B ) (isomer 5A ) D-mannose 8A B ) N 6 -lipoyl-L-lysine phosphomevalonate hydroxyoctadec- [tRNA His ] 1-phosphate UDP-α-D-galactose glucokinase: 1,2,3 2,3 1,2 1,2,3 1,2 His 11-enoyl-[acp] a tRNA acetyltransferase: D-mannose degradation UDP-N- UDP-galactopyranose D-glucopyranose CN62_RS06380 CN62_RS07865 D-glucopyranose Metabolic Regulator acetylmuramoylalanyl- mutase: CN62_RS14180 6-phosphate ditrans,octacis- UDP-N-acetyl- D-mannopyranose a long-linear (E)-1-(L-cystein-S- (E)-1-(L-cystein-S-yl)-N- S-(4-hydroxy- γ-L-glutamyl-(S)- a (6Z)-3- Biosynthesis D-glutamate--2, 6- fructose degradation a tRNA precursor with a 5' α-D-glucopyranose an N-terminal-L-methionyl- D-ribulose uridine undecaprenyldiphospho- α-D-glucosamine UDP-Galf 6-phosphate α-D-glucan yl)-N-hydroxy-2-(1H- hydroxy-ω-(methylsulfanyl) 3-methylbutan- trans-1-propenyl- reduced riboflavin oxooctadec- choline diaminopimelate mannose-6- extension and a short 3' extension L-cysteinyl-[protein] 5-phosphate ppGpp biosynthesis N-acetyl-(N- D-ala glycine-- 4-alpha- indol-3-yl)ethan-1-imine pentan-1-imine methionine 2-yl)-L-cysteine L-cysteine 6-enoyl-[acp] uridine kinase: ligase: CN62_RS10160 β-D-fructofuranose phosphate P cystathionine cystathionine cystathionine glutamyl hypothetical acetylglucosaminyl) tRNA ligase: glucanotransferase: aminopeptidase: phosphoribulokinase: flavin reductase: choline kinase: CN62_RS08805 gly 1-phosphate isomerase, class protein component: beta-lyase: beta-lyase: beta-lyase: aminopeptidase: protein: muramoyl-L-alanyl- D-alanine--D- CN62_RS09910 1-phosphofructokinase: CN62_RS13200 CN62_RS08265 CN62_RS04420 CN62_RS05945 CN62_RS09070 pppGpp UDP-N-acetyl- I: CN62_RS06715 CN62_RS12720 a short 1,4- CN62_RS06405 CN62_RS06405 CN62_RS06405 S-trans-1- CN62_RS11700 CN62_RS03855 γ a tRNA precursor with ω an N-terminal L- UMP bifunctional (p)ppGpp -D-isoglutaminyl- α-D-muramoyl- alanine ligase: CN62_RS09915 CN62_RS07385 α (E)-2-(1H-indol-3-yl)- (E)- -(methylsulfanyl) 2-methyl-3- D-ribulose-1,5- Gly β-D-fructose 1,6- F6P a tRNA fragment -D-glucan pyruvate pyruvate met pyruvate propenyl- glu a (3R,6Z)-3-[+ 2 isozymes] synthetase/guanosine- N-(β-D-asparaginyl) γ CN62_RS10820 a glycyl-[tRNA ] a short 3' extension 1-thioacetohydroximate pentyl-thiohydroximate cysteinyl-[protein] sulfanylbutan-1-ol riboflavin phosphocholine L-alanyl- -D- bisphosphate bisphosphate L-cysteine hydroxyoctadec- 3',5'-bis(diphosphate) 3'- -L-lysyl-D-alanine glutamyl-meso-2,6- a tRNA Gly D-alanyl-D-alanine 6-enoyl-[acp] pyrophosphohydrolase: diaminopimelate CN62_RS10685 guanosine 3'-diphosphate 5'-triphosphate 3'- UDP-N- a single RNase III mRNA (E)-1-(L-cystein-S-yl)-N- an N-terminal-L-methionyl- a [protein] with phosphoenol GTP pyrophosphokinase: a peptidoglycan maltopentaose D-glucopyranose an S-alkyl- pyridoxal diphosphatase: Alcohol Degradation processing hydroxy-ω-(methylsulfanyl) felinine an N-terminal L-cysteate CN62_RS08335 acetylmuramoyl- stranded DNA L-threonyl-[protein] L-cysteine pyruvate dimer (E. faecium methionine-- exodeoxyribonuclease 4-alpha- methionine CN62_RS10685 tripeptide-- met substrate heptan-1-iminecystathionine cystathionine L-glutamateglutamyl aspartate 3-oxoacyl-[acyl- , tetrapeptide) tRNA ligase: glucanotransferase: ribonuclease 3: cystathionine glycerol and glycerophosphodiester degradation VII large subunit: aminopeptidase: carrier-protein] pyruvate kinase: D-alanyl-D- glycerol degradation II glycerol degradation V CN62_RS08975 beta-lyase: beta-lyase: beta-lyase: aminopeptidase: aminotransferase: CN62_RS06960 an L-methionyl- CN62_RS08800 CN62_RS13200 RNase III CN62_RS08265 CN62_RS07495 alanine ligase: CN62_RS06405 CN62_RS06405 CN62_RS06405 CN62_RS11700 CN62_RS11385 reductase: [initiator tRNA Met ] a single-stranded a ribonucleoside maltose maltotetraose an mRNA fragment processing (E)-ω-(methylsulfanyl) an N-terminal L- 3-methyl-3- CN62_RS05405 CN62_RS10815 Met pyruvate met pyruvate pyruvate an alkyl-thiol initiator tRNA a glycerophosphodiester glycerol glycerol oligodeoxyribonucleotide 5'-monophosphate a peptide glu 3-sulfopyruvate pyruvate a peptidoglycan product mRNA heptyl-thiohydroximate threonyl-[protein] sulfanylbutan-1-ol 4-pyridoxolactone GTP ppGpp glycerol glycerol tetramer with an UDP-N-acetyl- dehydrogenase: dehydrogenase: L,D cross-link α-D-muramoyl- glycerophosphodiester CN62_RS04665 CN62_RS04665 (Enterococcus γ phosphodiesterase: (E)-1-(L-cystein-S-yl)-N- S-(5- L-alanyl- -D- D-cellobiose 34 a peptide with a supercoiled dihydroxyacetone dihydroxyacetone maltohexaose maltose S-fenclorimyl- a cytidine a folate nucleoside-diphosphate faecium) glutamyl-meso-2,6- di-trans,octa-cis CN62_RS07895 glycerol hydroxy-ω-(methylsulfanyl) hydroxypentan- lys an N-terminal asp ammonium hydrogencarbonate ATP 6'-phosphate L-cysteine in tRNA Ile2 duplex DNA 4-alpha- 6-phospho-beta- kinase: CN62_RS12270 diaminopimeloyl- -undecaprenyl glycerophosphodiester nonan-1-iminecystathionine cystathionine 3-yl)-L-cysteinecystathionine tRNA(Ile)-lysidine L-methioninemethionine dihydrofolate helicase: GTP pyrophosphokinase: glucanotransferase: glucosidase: aspartate D-alanyl-D-alanine phosphate phosphodiesterase: glycerol kinase: carbamate kinase: beta-lyase: beta-lyase: beta-lyase: synthetase: aminopeptidase: reductase: CN62_RS05940 CN62_RS08335 bifunctional (p)ppGpp CN62_RS13200 CN62_RS06710 aminotransferase: a peptidoglycan CN62_RS12140 CN62_RS13570 CN62_RS13410 CN62_RS06405 CN62_RS06405 CN62_RS06405 CN62_RS13885 CN62_RS08265 CN62_RS10365 [+ 3 isozymes] synthetase/guanosine- DHAP DHAP carbamoyl D-glucopyranose maltoheptaose D-glucopyranose (E)-ω-(methylsulfanyl) 6-chloro-2-phenyl- 3-sulfanylpentan- a lysidine 34 CN62_RS11385 with (L-alanyl- D-glucopyranose pyruvate pyruvate pyruvate a peptide met a single 3',5'-bis(diphosphate) 3'- phosphate 6-phosphate nonyl-thiohydroximate 4-sulfanylpyrimidine 1-ol in tRNA Ile2 a 7,8-dihydrofolate γ-D-glutamyl-L- sn-glycerol oxaloacetate stranded DNA pyrophosphohydrolase: lysyl-D-alanyl- undecaprenyldiphospho- 3-phosphate CN62_RS10685 D-alanine) N-acetylmuramoyl-L- alanyl-γ-D-glutamyl-meso a plant soluble (E)-1-(L-cystein-S-yl)-N- S-(4-hydroxy- S-(1- a (1->4)- GDP pentapeptide 7,8-dihydrofolate γ-L-glutamyl-(S)- D-glucopyranose NADPH H + an α-limit dextrin an L-cysteinyl- (S)-lactate -2,6-diaminopimeloyl- DL-allothreonine heteroglycan hydroxy-ω-(methylsulfanyl) 2-methylpentan- hydroxyhexan- methyl-L-cysteine α-D-glucan monoglutamate [tRNA Cys ] D-alanyl-D-alanine 4-alpha- dihydrofolate hexan-1-imine 2-yl)-L-cysteine 3-yl)-L-cysteine 4-alpha- glutamyl 1,4-alpha-glucan DHAP serine cystathionine cystathionine cystathionine peptidyl-tRNA undecaprenyldiphospho- glucanotransferase: reductase: aminopeptidase: branching L-lactate oxidase: Carboxylate Degradation beta-lyase: beta-lyase: beta-lyase: glucanotransferase: hydrolase: a peptidoglycan hydroxymethyltransferase: glyA CN62_RS13200 CN62_RS11700 protein GlgB: CN62_RS06555 muramoylpentapeptide beta-N- CN62_RS10365 CN62_RS13200 CN62_RS13855 a plant soluble 5,6,7,8- CN62_RS06405 CN62_RS06405 CN62_RS06405 with (L-alanyl- acetylglucosaminyltransferase: gly acetaldehyde maltose + (E)-ω-(methylsulfanyl) 4-methyl-4- 3-sulfanylhexan- a α-limit dextrin S-methyl- CN62_RS08440 L-ascorbate heteroglycan NADP pyruvate pyruvate pyruvate glu a tRNA Cys cys γ-D-glutamyl-L- CN62_RS06470 pyruvate fermentation tetrahydrofolate hexyl-thiohydroximate sulfanylpentan-2-ol 1-ol with short branches L-cysteine a GlgE-glycogen pyruvate degradation I lysyl-D-alanyl- lipid II (meso to acetate IV D-alanine) diaminopimelate (bacterial, anaerobic) L-ascorbate pentapeptide containing) pyruvate a nascent peptidoglycan with (L- (E)-1-(L-cystein-S-yl)-N- salicin 6- arbutin-6- a peptide with 6-phosphate maltohexaose D-glucopyranose a glucan maltotriose a [protein]-L- ω a kanamycin sec methylglyoxal L-ascorbate alanyl-γ-D-glutamyl-meso-2,6- hydroxy- -(methylsulfanyl) phosphate phosphate an N-terminal a tRNA ser proline (ω = 180) 4-alpha- 4-alpha- 6-phospho-beta- 6-phospho-beta- 6-phosphate diaminopimeloyl-D-alanine) tetrapeptide octan-1-iminecystathionine L-alanine aminoglycoside serine-- peptidylprolyl formate C- LD-carboxypeptidase: glucanotransferase: glucanotransferase: aminopeptidase glyoxalase: lactonase: glucosidase: glucosidase: phosphotransferase: tRNA ligase: acetyltransferase/ CN62_RS04260 beta-lyase: N: CN62_RS07010 isomerase: CN62_RS12665 a nascent peptidoglycan with CN62_RS13200 CN62_RS13200 CN62_RS06710 CN62_RS06710 CN62_RS03715 CN62_RS06405 β β CN62_RS05870 CN62_RS05360 CN62_RS06875 3-keto-L-gulonate glycerol D-ala (L-alanyl-γ-D-glutamyl-meso- maltose maltopentaose D-glucopyranose a glucan (E)-ω-(methylsulfanyl) -D-glucose -D-glucose a peptide ala an L-seryl- pyruvate salicyl alcohol hydroquinone a kanamycin a [protein]-L- 6-phosphate dehydratase 6-phosphate 6-phosphate sec 2,6-diaminopimelate) tripeptide octyl-thiohydroximate 3'-phosphate [tRNA ] ω (R)-lactate family glycyl proline ( = 0) 3-dehydro-L- radical : gulonate-6- CN62_RS04655 phosphate N-acetyl-D-glucosaminyl-N- RNase R degradation (Z)-1-(L-cystein-S a [lipoyl-carrier D-ribulose (R)-propane- a maltodextrin D-glucopyranose GSSH sulfite (R)-lipoate hydrogencarbonate H + L-rhamnulofuranose ethylene glycol decarboxylase formate C- acetylmuramoyl-L-alanyl-D-glutamyl- substrate RNA -yl)-N-hydroxy-2- protein]-L-lysine 5-phosphate 1,2-diol 4-alpha- rhodanese domain- lipoate-- carbonic UlaD: ulaD acetyltransferase: 6-carboxy-L-lysyl-D-alanine ribonuclease R: phenylethan-1-iminecystathionine ribitol-5-phosphate lactaldehyde lactaldehyde LD-carboxypeptidase: glucanotransferase: rhamnulokinase: CN62_RS05580 CN62_RS07815 containing protein: protein ligase: anhydrase: L-xylulose CN62_RS04260 beta-lyase: dehydrogenase: reductase: reductase: N-acetyl-D-glucosaminyl-N- CN62_RS13200 a nucleoside 5'- CN62_RS03810 CN62_RS14575 CN62_RS03510 CN62_RS13490 CN62_RS06405 CN62_RS09075 CN62_RS13445 CN62_RS13445 5-phosphate a diribonucleotide a [lipoyl-carrier protein]- D-ala acetylmuramoyl-L-alanyl-D- maltose a maltodextrin monophosphate (Z)-2-phenyl-1- thiosulfate glutathione H O CO L-rhamnulose pyruvate 6 2 2 D-ribitol 5- L-ribulose-5- acetyl-CoA formate N -lipoyl-L-lysine (R)-lactaldehyde glycolaldehyde glutamyl-6-carboxy-L-lysine thioacetohydroximate 1-phosphate phosphate phosphate 3- phosphate epimerase: acetyltransferase: CN62_RS12680 a DNA containing CN62_RS08350 5-amino-4- maltotetraose D-glucopyranose S-benzyl- D-ribulose Inorganic Nutrient Metabolism PRPP an apurinic/ a peptide with a a tripeptide canavaninosuccinate a RNA-DNA hybrid D-sedoheptulose D-altropyranose L-ribulose 5- imidazolecarboxyamide 5-phosphate 4-alpha- leader sequence L-cysteine phosphate adenine apyrimidinic site peptidase T: argininosuccinate ribonuclease HII: L-fucose acetyl phosphate III: signal peptidase cystathionine ribitol-5-phosphate phosphoribosyltransferase: glucanotransferase: lyase: fructokinase: L-ribulose-5- urea cycle CN62_RS07965 CN62_RS08570 beta-lyase: dehydrogenase: isomerase: CN62_RS13200 CN62_RS09120 I: CN62_RS05320 CN62_RS11065 thiosulfate CN62_RS10400 a 3'-terminal a 5'-phospho- a proteinogenic CN62_RS03950 a nucleoside 5'- CN62_RS13450 phosphate 4- acetate kinase: a dipeptide DNA CN62_RS06405 CN62_RS09075 disproportionation AICAR maltose maltotriose unsaturated sugar [DNA] a leader sequence a peptide amino acid fumarate L-canavanine monophosphate D-sedoheptulose epimerase: CN62_RS12725 pyruvate benzyl thiol D-ribitol 5- keto-D-psicose arg IV (rhodanese) CN62_RS12675 phosphate 1-phosphate D-xylulose acetate thiosulfate 5-phosphate rhodanese domain- argininosuccinate ammonium a 5S rRNA (E)-1-(L-cystein-S-yl)-N-hydroxy- a dipetide with an N- D-erythrose D-xylulose containing protein: acetoacetyl-CoA H O acetyl-CoA maltoheptaose FMNH NADP + an L-cysteine- maltose acetylxylan lyase: 2 ω 2 S-ethyl-L-cysteine CN62_RS03810 precursor -(methylsulfanyl)butan-1-imine terminal L-aspartate 4-phosphate 5-phosphate S-conjugate CN62_RS03950 carbamoyl- hydroxymethylglutaryl-CoA ribonuclease M5: alpha-glucosidase: cystathionine dipeptidase PepV: transketolase: flavin reductase: alpha- acetylxylan sulfite thiocyanate cystathionine cystathionine phosphate CN62_RS05035 beta-lyase: esterase: synthase: CN62_RS11095 CN62_RS12420 CN62_RS06195 CN62_RS13305 CN62_RS05945 beta-lyase: beta-lyase: glucosidase: CN62_RS10930 L-arginino- synthase: a double-stranded D-glucopyranose maltohexaose CN62_RS06405 a proteinogenic [+ 3 isozymes] + CN62_RS05035 L-ornithine HMG-CoA a mature 5S-rRNA (E)-ω-(methylsulfanyl) asp D-glyceraldehyde H NADPH FMN CN62_RS06405 CN62_RS06405 succinate CN62_RS09100 oligonucleotide amino acid pyruvate F6P pyruvate ethanethiol pyruvate a thiol D-glucopyranose acetate xylan CN62_RS09105 butyl-thiohydroximate 3-phosphate carbamoyl ornithine phosphate a (1->4)- methyl β-D-glucoside a large- a β-D-fructofuranoside maltohexaose maltopentaose maltotriose FMN NAD(P)H H + FMNH NAD + xylan carbonic acid carbamoyltransferase: α-D-glucan 2 6-phosphate branched glucan beta-fructofuranosidase: alpha-glucosidase: alpha-glucosidase: alpha-glucosidase: alpha- CN62_RS13405 flavin reductase: flavin reductase: 6-phospho-beta- carbonic alpha-xylosidase: pullulanase: CN62_RS11360 CN62_RS05035 CN62_RS05035 CN62_RS05035 glucosidase: CN62_RS05945 CN62_RS05945 glucosidase: anhydrase: L-citrulline CN62_RS04905 CN62_RS04735 a glycoside β-D-fructofuranose D-glucopyranose maltopentaose D-glucopyranose maltotetraose D-glucopyranose maltose CN62_RS05035 CN62_RS06710 CN62_RS03510 a (1->4)- NAD(P) + FMNH H + NADH FMN β-D-glucose D-glucopyranose 2 MeOH a long-linear CO H O α-D-glucan 6-phosphate α-D-xylopyranose 2 2 a branched- α-D-glucan N-acetyl-α-D- chain an amino an amino an amino an amino an amino an amino an amino galactosamine an N-acetyl-α-D-galactosamine 1-phosphate N-acetyl-α-D-galactosamine 1-phosphate N-acetyl-α-D-galactosamine 1-phosphate L-ascorbate L-ascorbate amino acid D-mannose D-mannose D-fructose D-fructose D-fructose a sugar 6- a sugar 6- a sugar 6- acid acid acid acid acid acid acid lactose 6'- 1-phosphate phosphate phosphate oligopeptide 1-(β-D N-acetyl-α-D-galactosamine 1-phosphate an L-sorbose 1-phosphate an L-sorbose 1-phosphate N-acetyl-α-D-galactosamine 1-phosphate an L-sorbose 1-phosphate an L-sorbose 1-phosphate a β- a β- 6-phosphate 6-phosphate a branched- a branched- a maltodextrin ferrichrome 6-phosphate 6-phosphate 1-phosphate 1-phosphate 1-phosphate phosphate phosphate phosphate an amino an amino an amino an amino an amino phosphate a carbohydrate ribofuranosyl) D-fructose 1-phosphate D-fructose 1-phosphate D-fructose 1-phosphate D-fructose 1-phosphate D-fructose 1-phosphate D-fructose 1-phosphate D-fructose D-fructose 3,5- a sugar 6- a C4- a C4- glucoside 6- glucoside 6- chain chain lactose 6'- D-trehalose lactose 6'-phosphate lactose 6'-phosphate lactose 6'-phosphate lactose 6'-phosphate galactitol 1- D-glucose 6- queuosine an antibiotic phosphate a nucleotide 1-phosphate 1-phosphate dimethoxytoluene phosphate dicarboxylate dicarboxylate acid acid acid acid acid an aromatic an aromatic phosphate a carbohydrate a carbohydrate a carbohydrate a carbohydrate 6-phosphate D-cellobiose 6'-phosphate D-cellobiose 6'-phosphate D-cellobiose 6'-phosphate D-cellobiose 6'-phosphate phosphate phosphate nicotinamide D-mannose 6-phosphate D-mannose 6-phosphate D-mannose 6-phosphate D-mannose 6-phosphate D-mannose 6-phosphate D-mannose 6-phosphate phosphate phosphate predicted amino acid amino acid a macrolide phosphate carboxylate carboxylate predicted predicted predicted predicted predicted predicted predicted predicted predicted predicted predicted ABC predicted predicted predicted predicted predicted predicted predicted predicted predicted PEP-driven predicted predicted predicted predicted ATP-driven ABC ABC ABC ABC ABC ABC ABC PEP-driven PEP-driven transporter predicted ABC PEP-driven PEP-driven PEP-driven PEP-driven PEP-driven PEP-driven PEP-driven PEP-driven PEP-driven transporter ABC ABC ABC ABC transporter RS11670 RS03685 RS03690 RS04805 RS04950 RS04955 RS13470 RS08750 RS07390 RS09780 RS07985 RS13475 RS12610 RS05355 transporter transporter RS06125 RS05540 RS07930 RS04110 RS09600 transporter transporter transporter transporter transporter RS11230 RS05695 RS05995 RS11070 RS06245 transporter transporter of a RS04100 RS06210 RS13320 RS11370 RS06670 RS03800 transporter of RS11840 RS11785 RS11435 RS04640 RS08695 RS12635 RS06280 RS06815 RS0102380 RS05680 RS13100 RS05750 transporter transporter transporter transporter transporter transporter transporter transporter transporter of N-acetyl- transporter of transporter transporter transporter of an of an of an of an of an of an of an of an of L- of L- branched- a carbohydrate of D-mannose of D-mannose of D-fructose of D-fructose of D-fructose of a sugar of a sugar of a sugar of lactose alpha-D- a maltodextrin of ferrichrome of phosphate of phosphate oligopeptide amino acid amino acid amino acid amino acid amino acid amino acid amino acid ascorbate ascorbate chain galactosamine amino acid

an 1-(β-D N-acetyl-α-D-galactosamine N-acetyl-α-D-galactosamine L-sorbose N-acetyl-α-D-galactosamine N-acetyl-α-D-galactosamine N-acetyl-α-D-galactosamine 3,5- a C4- a C4- a branched- a branched- a branched- N-acetyl-α-D- lactose lactose lactose lactose D-mannose D-mannose D-fructose D-fructose D-fructose D-fructose D-fructose queuosine a sugar a sugar a sugar a sugar an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino a β-glucoside a β-glucoside an antibiotic L-ascorbate L-ascorbate lactose lactose a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate trehalose a maltodextrin ferrichrome galactitol D-glucose a nucleotide oligopeptide ribofuranosyl) D-fructose L-sorbose D-fructose D-fructose L-sorbose L-sorbose dicarboxylate dicarboxylate an aromatic an aromatic chain chain chain galactosamine D-cellobiose D-cellobiose D-cellobiose D-cellobiose phosphate phosphate phosphate dimethoxytoluene acid acid acid acid acid acid acid acid acid acid acid acid a macrolide nicotinamide D-mannose D-fructose D-mannose D-mannose D-fructose D-fructose carboxylate carboxylate amino acid amino acid amino acid phosphate D-mannose D-mannose D-mannose This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.