Generated by SRI International Pathway Tools Version 25.0, Authors S

Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000166655Cyc: Borreliella burgdorferi JD1 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari

phosphate phosphate

predicted ABC RS03465 transporter RS01760 of phosphate

phosphate

Amino Acid Fatty Acid and Lipid Biosynthesis Aminoacyl-tRNA Charging Degradation undecaprenyl- 1-stearoyl- 1-myristoyl- 1-stearoyl- N-acetyl-D- 1518 2251 1-cis-vaccenoyl- 1-cis-vaccenoyl- 1-myristoyl- Nucleoside and Nucleotide Biosynthesis Macromolecule Modification linoleate a 2,3,4-saturated a 2,3,4-saturated 2- an acyl-[acyl- adenine / guanosine 1-(18-hydroxyoleoyl)- superpathway of guanosine Carbohydrate Degradation sn-glycerol a palmitoleoyl-[acp] sn-glycerol a palmitoyl-[acp] sn-glycerol galactosamine 1519 sn-glycerol- sn-glycerol- sn-glycerol superpathway of pyrimidine deoxyribonucleoside salvage superpathway of pyrimidine deoxyribonucleotides adenine salvage diphospho-N- fatty acyl-[acp] lysophosphatidate carrier protein] adenine in 16S rRNA in 23S rRNA sn-glycrol 3-phosphate dIDP nucleotides de novo biosynthesis I pyrimidine phosphatidylglycerol tRNA charging L-glutamine long-chain fatty acid--CoA 3-phosphate 3-phosphate 3-phosphate 6-phosphate ribosomal RNA 23S rRNA 3-phosphate 3-phosphate 3-phosphate adenosine nucleotides de novo biosynthesis III long-chain fatty acetylmuramoyl- UDP-N-acetyl- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- N-acetylglucosamine- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- ribonucleosides salvage I biosynthesis II lipoprotein posttranslational degradation I γ α ligase: BBUJD1_RS04530 small subunit (guanosine(2251)-2'- 2'-deoxycytidine de novo biosynthesis I acid activation queuosine biosynthesis glycogen degradation II L-alanyl- -D- -D-glucosamine 3-phosphate 3-phosphate 3-phosphate 3-phosphate 6-phosphate 3-phosphate 3-phosphate 3-phosphate 3-phosphate nucleoside- UDP CTP (non-plastidic) modification undecaprenyldiphospho- methyltransferase A: O)-methyltransferase IMP adenine cytidine arg arginine-- D-xylose degradation I glutamyl-L-lysyl- long-chain fatty acid--CoA acyltransferase: acyltransferase: acyltransferase: acyltransferase: deacetylase: acyltransferase: acyltransferase: acyltransferase: acyltransferase: diphosphate kinase: a long-chain gln muramoylpentapeptide beta-N- BBUJD1_RS04515 RlmB: cytidine deaminase: 2'-deoxycytidine DHAP tRNA ligase: a [prolipoprotein]- a glycogen D-alanyl-D-alanine ditrans,octacis- ligase: BBUJD1_RS02230 BBUJD1_RS03180 BBUJD1_RS01740 BBUJD1_RS03180 BBUJD1_RS03180 BBUJD1_RS02290 N 6 -dimethyladenine 1518 BBUJD1_RS03180 BBUJD1_RS03180 BBUJD1_RS03180 BBUJD1_RS03180 BBUJD1_RS03895 asp IMP fatty acid preQ CTP synthase: pyrG acetylglucosaminyltransferase: D-galactosamine BBUJD1_RS04150 BBUJD1_RS04675 kinase: cytidine deaminase: NAD(P)H- long-chain fatty BBUJD1_RS04535 an L-arginyl- L-cysteine 0 D-xylose /N 6 -dimethyladenine 1519 guanosine dUDP CDP GMP synthase undecaprenyldiphospho-BBUJD1_RS05435 AMP diphosphate linoleoyl-CoA 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- acetate 6-phosphate 2-O- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- BBUJD1_RS02745 BBUJD1_RS04675 dependent glycerol- acid--CoA ligase: [tRNA Arg ] 2251 dITP monophosphate adenine adenine deaminase: prolipoprotein N-acetyl-(N-acetyl-β-D- 3-phosphate 3-phosphate 3-phosphate 3-phosphate in 16S rRNA methylguanosine 3-phosphate 3-phosphate 3-phosphate 3-phosphate 2'-deoxyuridine adenylo-succinate nucleoside- CMP 3-phosphate BBUJD1_RS02230 a tRNA Arg (glutamine- UDP reductase: phosphoribosyltransferase: BBUJD1_RS06155 diacylglyceryl hydrolyzing): glucosaminyl)muramoyl- acyltransferase: acyltransferase: acyltransferase: acyltransferase: in 23S rRNA acyltransferase: acyltransferase: acyltransferase: acyltransferase: dCMP diphosphate kinase: uridine dehydrogenase: long-chain fatty preQ D-xylulose γ BBUJD1_RS06320 BBUJD1_RS05490 adenine deaminase: transferase: 1 α L-alanyl- -D-glutamyl-L- BBUJD1_RS01740 BBUJD1_RS03180a 1-stearoyl 2- BBUJD1_RS01740 BBUJD1_RS01740 1-[18-hydroxyoeoyl]-2-BBUJD1_RS01740 1,2-dicis- BBUJD1_RS01740 BBUJD1_RS01740 BBUJD1_RS01740 thymidine kinase: BBUJD1_RS03895 dCDP BBUJD1_RS03380 acid--CoA ligase: an -limit dextrin BBUJD1_RS06325 a 2,3,4-saturated 1-myristoyl-2- 1-stearoyl- 1-cis-vaccenoyl- 1-myristoyl-2- cytidylate kinase: BBUJD1_RS06090 uridine kinase: sn-glycerol BBUJD1_RS03350 lysyl-D-alanyl-D-alanine acyl-carrier protein acyl-sn-glycerol [18-hydroxy-lioleoyl]-sn vaccenoyl- BBUJD1_RS05565 BBUJD1_RS04530 tRNA guanosine(34) xylulokinase: glu acyl-carrier protein 1,2-diacyl-sn acyl-carrier protein palmitoleoyl- acyl-carrier protein 2-palmitoyl- 2-palmitoleoyl- palmitoleoyl- XMP BBUJD1_RS05700 dUTP nucleoside- BBUJD1_RS01630 3-phosphate a long-chain a [prolipoprotein]- 4-alpha- 3-phosphate -glycerol 3-phosphate phosphatidate deoxynucleoside transglycosylase Tgt: BBUJD1_RS04285 -glycerol 3- sn-glycerol sn-glycerol sn-glycerol- sn-glycerol thymidine cytidylate kinase: diphosphate kinase: AMP UMP fatty acyl-CoA cysteine-- S-1,2-diacyl-sn- glucanotransferase: kinase: cys BBUJD1_RS05655 D-xylulose phosphate 3-phosphate 3-phosphate 3-phosphate 3-phosphate GMP synthase BBUJD1_RS02185 AMP BBUJD1_RS03895 tRNA ligase: glyceryl-L-cysteine a 7-aminomethyl-7- BBUJD1_RS02365 BBUJD1_RS02745 hypoxanthine 5-phosphate (glutamine-hydrolyzing) thymidine kinase: BBUJD1_RS04560 an L-cysteinyl- deazaguanosine 34 a debranched dCDP dUMP dCTP signal peptidase II: 1-cis-vaccenoyl- a 3-methyl- 1-palmitoyl- 1-stearoyl- a 2'- an N-terminal- 527 a 1-alkyl-sn 1-palmitoyl- : BBUJD1_RS06325 BBUJD1_RS05565 a 1-acyl-sn [tRNA Cys ] in tRNA α-limit dextrin a negatively a guanine adenylate kinase: hypoxanthine 16-hydroxypalmitate decanoate branched 2,3,4- deoxyribonucleoside [DNA] dUMP deoxynucleoside nucleoside- thymidylate purine deoxyribonucleosides salvage -glycerol 3- a tRNA Cys BBUJD1_RS03925 a palmitoleoyl-[acp] sn-glycerol- a palmitoleoyl-[acp] sn-glycerol a stearoyl-[acp] sn-glycerol L-methionyl-L- GTP H O supercoiled DNA in 16S rRNA -glycerol 3- sn-glycerol IDP BBUJD1_RS03630 phosphoribosyltransferase: long-chain fatty acid--CoA long-chain fatty acid--CoA saturated fatty acid 5'-triphosphate 2 DNA topoisomerase GMP kinase: diphosphate kinase: synthase (FAD): phosphate 1-acyl-sn-glycerol-3-phosphate long-chain fatty 1-acyl-sn-glycerol-3-phosphate 1-acyl-sn-glycerol-3-phosphate DNA polymerase III: seryl-[protein]methionine 16S rRNA phosphate1-acyl-sn-glycerol- 3-phosphate1-acyl-sn-glycerol- BBUJD1_RS05490 phosphatidylcholine an (S-diacyl- ligase: BBUJD1_RS04530 ligase: BBUJD1_RS04530 GTPase Era: IV subunit A: BBUJD1_RS02745 BBUJD1_RS03895 BBUJD1_RS00320 1-acyl-sn-glycerol- a lipoprotein 3-phosphate acid--CoA ligase: 3-phosphate 3-phosphate BBUJD1_RS03835 aminopeptidase: (guanine(527)-N(7) 3-phosphate 3-phosphate nucleoside- sn-glyceryl) 34 D-mannose degradation BBUJD1_RS04900 2'-deoxyguanosine 2'-deoxyadenosine 3-phosphate biosynthesis VI signal peptide an epoxyqueuosine α-D- long-chain fatty acid--CoA long-chain fatty acid--CoA acyltransferase: BBUJD1_RS04530 acyltransferase: acyltransferase: BBUJD1_RS03885 BBUJD1_RS02070 BBUJD1_RS01730 )-methyltransferase diphosphate kinase: dCTP ADP dTMP IMP -L-cysteinyl- D-glucopyranose GTPase ObgE: acyltransferase: acyltransferase: guanylate kinase: deoxynucleoside deoxynucleoside acyltransferase: a CDP- in tRNA glucopyranose ligase: BBUJD1_RS02230 ligase: BBUJD1_RS02230 BBUJD1_RS03180 BBUJD1_RS03180 BBUJD1_RS03180 an N-terminal DNA topoisomerase RsmG: BBUJD1_RS03895 H + RS02995 H + choline [apolipoprotein] D-mannopyranose long-chain fatty [+ 3 isozymes] met BBUJD1_RS05510 BBUJD1_RS01740 BBUJD1_RS03180 BBUJD1_RS03910 dTMP kinase: BBUJD1_RS01740 L-seryl-[protein] 1: BBUJD1_RS05740 7 BBUJD1_RS02420 kinase: kinase: diacylglycerol gln 1-phosphate 6-phosphate 1-acyl-sn-glycerol- acid--CoA ligase: 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- [DNA] an N - 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- BBUJD1_RS05575 phosphatidylcholine mannose-6- AMP diphosphate 16-hydroxypalmitoyl-CoA diphosphate AMP decanoyl-CoA phosphate GDP H + BBUJD1_RS02745 BBUJD1_RS02745 1-acyl-sn-glycerol- BBUJD1_RS02230 a relaxed DNA methylguanine 527 ITP UTP and CTP de synthase: an L-glutaminyl- 3-phosphate a 3-methyl- 3-phosphate 3-phosphate 3-phosphate 3-phosphate dTDP dGMP dAMP 3-phosphate phosphoglucomutase: phosphate in 16S rRNA GDP novo biosynthesis BBUJD1_RS02795 Gln a peptide a queuosine 34 acyltransferase: branched acyltransferase: acyltransferase: acyltransferase: acyltransferase: V-type ATP CMP phosphorylation acyltransferase: [tRNA ] an N-acyl-(S- BBUJD1_RS01575 isomerase, class I: diphosphate AMP H + H + nucleoside- a phosphatidylcholine a tRNA Gln in tRNA BBUJD1_RS017401-cis-vaccenoyl- 2,3,4-saturated BBUJD1_RS017401-palmitoyl-2- BBUJD1_RS017401-stearoyl-2- a 2-acyl-1-alkyl-BBUJD1_RS03180 1-palmitoyl-2-BBUJD1_RS01740 synthase UMP BBUJD1_RS03180 diacyl-sn-glyceryl) BBUJD1_RS03585 dTMP dADP diphosphate kinase: 2-palmitoleoyl- fatty acyl-CoA palmitoleoyl- stearoyl-sn sn-glycerol palmitoleoyl- CMP UMP kinase: a 1,2-diacyl- -L-cysteinyl- D-glucopyranose F6P acyl-carrier protein acyl-carrier protein acyl-carrier protein nucleoside- dTMP kinase: BBUJD1_RS03895 6-phosphate sn-glycerol- sn-glycerol -glycerol 3- 3-phosphate sn-glycerol cytidylate kinase: BBUJD1_RS04420 sn-glycerol [lipoprotein] glycine glycine diphosphate kinase: BBUJD1_RS05575 nucleoside- 3-phosphate 3-phosphate phosphate 3-phosphate RS02270 BBUJD1_RS05700 diphosphate kinase: dTTP [+ 2 isozymes] 3-phosphate betaine betaine BBUJD1_RS03895 UDP phosphatidate N 6 -L-threonylcarbamoyladenosine 37 Nucleoside and dTDP cytidylate kinase: BBUJD1_RS03895 dGDP dADP glu cytidylyltransferase: -modified tRNA biosynthesis Nucleotide Degradation dGDP BBUJD1_RS02185 nucleoside- fructose degradation 1-stearoyl- α,ω-9Z- 1-myristoyl- a 1-acyl-sn a guanine 34 an N-terminal- a [release factor]- a guanine 966 1-myristoyl- a 1-acyl-sn nucleoside- (15Z)-tetracosenoate octanoate an acyl-[acyl- queuine a RNA-DNA hybrid CDP nucleoside- nucleoside- diphosphate kinase: BBUJD1_RS02140 an L-glutamyl- an oleoyl-[acp] sn-glycerol octadecenedioate a myristoyl-[acp] sn-glycerol -glycerol 3- in tRNA L-methionyl-L- L-glutamine in 16S rRNA sn-glycerol -glycerol 3- GTP diphosphate kinase: dATP S-methyl-5'-thioadenosine carrier protein] IMP predicted nucleoside- BBUJD1_RS03895 nucleoside- diphosphate kinase: diphosphate kinase: BBUJD1_RS03895 a CDP- [tRNA Glu ] ATP thr β-D-fructofuranose degradation IV long-chain fatty acid--CoA long-chain fatty acid--CoA 1-acyl-sn-glycerol-3-phosphate long-chain fatty 1-acyl-sn-glycerol-3-phosphate 1-acyl-sn-glycerol-phosphate tRNA guanosine(34) valyl-[protein]methionine ribonuclease HII: peptide chain 16S rRNA 3-phosphate1-acyl-sn-glycerol- phosphate1-acyl-sn-glycerol- glu guanosine ABC diphosphate kinase: diphosphate kinase: BBUJD1_RS03895 BBUJD1_RS03895 diacylglycerol a tRNA 1-phosphate ligase: BBUJD1_RS02230 ligase: BBUJD1_RS04530 3-phosphate acid--CoA ligase: 3-phosphate 3-phosphate transglycosylase Tgt: aminopeptidase: BBUJD1_RS01780 release factor (guanine(966)-N(2) Peptide Peptide dTTP UTP threonylcarbamoyl- 1-phosphofructokinase: S-methyl-5'- 3-phosphate 3-phosphate monophosphate transporter BBUJD1_RS03895 BBUJD1_RS03895 CDP-diacylglycerol-- long-chain fatty acid--CoA long-chain fatty acid--CoA acyltransferase: BBUJD1_RS02230 acyltransferase: acyltransferase: BBUJD1_RS05655 BBUJD1_RS02070 ribonuclease HI: N(5)-glutamine )-methyltransferase acyltransferase: acyltransferase: dGTP dATP AMP synthase: BBUJD1_RS04745 thioadenosine an N-terminal methyltransferase: RsmD: reductase: of a peptide CTP synthase: pyrG glycerol-3-phosphate 3- β-D-fructose 1,6- 5'-methylthioadenosine/ ligase: BBUJD1_RS04530 ligase: BBUJD1_RS02230 BBUJD1_RS03180 long-chain fatty BBUJD1_RS03180 BBUJD1_RS01740 a queuosine 34 met BBUJD1_RS05800 BBUJD1_RS03180 BBUJD1_RS03180 CTP BBUJD1_RS07845 guanine L-valyl-[protein] a nucleoside 5'- BBUJD1_RS02515 BBUJD1_RS02575 BBUJD1_RS06320 dGTP phosphatidyltransferase: bisphosphate adenosylhomocysteine acid--CoA ligase: in tRNA DNA 2 AMP diphosphate (15Z)-tetracosenoyl-CoA diphosphate AMP octanoyl-CoA 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- a [release factor]-N 5 an N - 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- Peptide RS00130 Peptide threonylcarbamoyl- BBUJD1_RS04530 monophosphate 966 GMP CTP BBUJD1_RS05205 isoleucine-- nucleosidase: 3-phosphate 3-phosphate 3-phosphate methylguanine 3-phosphate 3-phosphate 1-(3-sn- ile AMP synthase: ω-carboxy- -methyl-L-glutamine tRNA ligase: BBUJD1_RS03415 acyltransferase: acyltransferase: acyltransferase: in 16S rRNA acyltransferase: acyltransferase: phosphatidyl) (L-threonylcarbamoyl)BBUJD1_RS05270 AMP diphosphate (9Z)-octadec- BBUJD1_RS05765 an L-isoleucyl- [+ 2 isozymes] BBUJD1_RS01740 BBUJD1_RS01740 BBUJD1_RS03180 BBUJD1_RS01740 BBUJD1_RS01740 -sn-glycerol adenylate 1-stearoyl-2- 9-enoyl-CoA 1,2-dimyristoyl- a 1,2-diacyl- 1,2-dimyristoyl- a 1-acyl-2- Peptide RS05335 Peptide [tRNA Ile ] MTR 6 acyl-carrier protein oleoyl-sn-glycerol acyl-carrier protein sn-glycerol acyl-carrier protein sn-glycerol sn-glycerol palmitoyl-sn 3-phosphate a tRNA Ile N -L- threonylcarbamoyladenine 3-phosphate 3-phosphate 3-phosphate 3-phosphate -glycerol 3- synthase: BBUJD1_RS05445 phosphate 6 Peptide RS06315 Peptide an L-1- an N -L- threonylcarbamoyladenine 37 phosphatidyl- Carboxylate Degradation a (2R)-2-hydroxy 3-[(3aS,4S,5R,7aS)-5- 1-palmitoyl- an N-terminal-L-methionyl- β-D-fructofuranose a cytidine 1402 a double-stranded 1-palmitoyl- in tRNA 18-hydroxystearate stearate a cis- a nucleoside a peptide with a Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis sn-glycerol leu even numbered hydroxy-7a-methyl-1-oxo- sn-glycerol a ribonucleic acid L-cysteinyl-[protein] 1-phosphate in 16S rRNA oligonucleotide sn-glycerol a protein ala leucine--tRNA ligase: vaccenoyl-[acp] triphosphate leader sequence methionine bifunctional pyruvate fermentation long-chain fatty acid--CoA long-chain fatty acid--CoA straight chain octahydro-1H-inden-4- 1-acyl-sn-glycerol-3-phosphate DNA-directed signal peptidase I: class II fructose- ribosomal RNA 3-phosphate1-acyl-sn-glycerol- ATP-dependent Peptide RS00075 Peptide BBUJD1_RS02810 an L-leucyl- acetyl-CoA C- aminopeptidase: oligoribonuclease/ to acetate IV ligase: BBUJD1_RS04530 ligase: BBUJD1_RS04530 2,3,4-saturatedlong-chain fatty yl]-3-oxopropanoyl-CoA 3-phosphate RNA polymerase: BBUJD1_RS01705 bisphosphate small subunit 3-phosphate Clp protease alanine racemase: [2Fe-2S] iron-sulfur cluster biosynthesis [tRNA Leu ] acyltransferase: BBUJD1_RS02070 PAP phosphatase L-cysteine biosynthesis coenzyme A biosynthesis I (prokaryotic) mevalonate degradation long-chain fatty acid--CoA long-chain fatty acid--CoA fatty acid acid--CoA ligase: acyltransferase: BBUJD1_RS03480 [+ 2 isozymes] aldolase: methyltransferase H: acyltransferase: proteolytic subunit: BBUJD1_RS02335 di-trans,poly-cis-undecaprenyl a tRNA Leu 3-[(3aSBBUJD1_RS02090,4S,5R,7aS)- ligase: BBUJD1_RS02230 ligase: BBUJD1_RS02230 an N-terminal L- BBUJD1_RS03785 4 BBUJD1_RS03085 NrnA: VI (from L-methionine) pyruvate BBUJD1_RS04530 BBUJD1_RS03180 BBUJD1_RS03485 met an N - BBUJD1_RS03180 BBUJD1_RS04635 2+ 2+ phosphate biosynthesis 5-hydroxy-7a-methyl- a leader sequence a peptide cysteinyl-[protein] BBUJD1_RS04680 Mg RS03440 Mg (R)-4'- Glycolysis acetyl-CoA 1402 L-cysteine desulfurase (R)-mevalonate long-chain fatty 1-oxo-octahydro-1H- 1-acyl-sn-glycerol- [+ 2 isozymes] D-glyceraldehyde DHAP methylcytidine 1-acyl-sn-glycerol- ATP-dependent D-ala phosphopantothenate (2E,6E)-farnesyl AMP diphosphate 18-hydroxystearoyl-CoA diphosphate AMP stearoyl-CoA a nucleoside 5'- met bifunctional IPP hydroxymethylglutaryl- acid--CoA ligase: indene-4-carboxyl-CoA 3-phosphate a ribonucleic acid in 16S rRNA 3-phosphate Clp protease diphosphate Cell Structure Biosynthesis a (R)-2-hydroxy monophosphate cysteine desulfurase: S-adenosylmethionine phosphopantothenoylcysteine di-trans,poly-cis- glycolysis I (from glucose 6-phosphate) CoA reductase, BBUJD1_RS02230even numbered acyltransferase: acyltransferase: proteolytic subunit: BBUJD1_RS01965 synthase: decarboxylase/ decaprenylcistransferase: val degradative: BBUJD1_RS01740 BBUJD1_RS01740 BBUJD1_RS05385 valine--tRNA ligase: diphosphate AMP straight chain 1-palmitoyl-2- 1-palmitoyl-2- BBUJD1_RS03420 phosphopantothenate--cysteine di-trans,octa-cisBBUJD1_RS02145 peptidoglycan biosynthesis I (meso-diaminopimelate containing) D-glucopyranose acetyl-CoA formate BBUJD1_RS05025 2,3,4-saturated acyl-carrier protein cis-vaccenoyl cis-vaccenoyl a peptide an S-sulfanyl-[L- SAM BBUJD1_RS05285 an L-valyl- 6-phosphate (R)-4'- ligase CoaBC: BBUJD1_RS05670 -undecaprenyl HMG-CoA fatty acyl CoA phosphatidate phosphatidate cysteine desulfurase] diphosphate UDP-N-acetyl-α-D-glucosamine [tRNA Val ] phosphate phosphopantothenoyl- a tRNA Val glucose-6- acetyltransferase: undecaprenyl- UDP-N-acetylglucosamine L-cysteine pyridoxal 5'-phosphate salvage I 38- diphosphate phosphate BBUJD1_RS04510 an odd numbered a Chi-site containing 1-palmitoyl- a [DNA]-3'- a 5'-phospho- an N-terminal-L-methionyl- a 5-aminomethyl-2- a cytidine 1402 a uridine 1-palmitoyl- bifunctional 1-carboxyvinyltransferase: (2E)-hexadecenoate laurate NAD + an N-modified NAD + phosphatase: isomerase: pgi acetoacetate acetyl-CoA straight chain double stranded RecA sn-glycerol a myristoyl-[acp] hydroxyl [DNA] L-threonyl-[protein] thiouridine 34 in tRNA in 16S rRNA 40 in tRNA sn-glycerol a protein phosphopantothenoylcysteine BBUJD1_RS03940 acetyl phosphate aminoacyl-[tRNA] methionine an S-sulfanyl-[cysteine SAH BBUJD1_RS02845 pyridoxine pyridoxamine long-chain fatty acid--CoA long-chain fatty acid--CoA 2,3,4-saturated DNA with a blunt end exodeoxyribonuclease 3-phosphate 1-acyl-sn-glycerol- DNA aminoacyl-tRNA tRNA 2- 16S rRNA tRNA 3-phosphate1-acyl-sn-glycerol- endopeptidase La: decarboxylase/ UDP-N-acetyl-α-D- long-chain fatty aminopeptidase: NAD(+) kinase: desulfurase]-[disordered- F6P ligase: BBUJD1_RS02230 ligase: BBUJD1_RS04530 fatty acid V: BBUJD1_RS04760 3-phosphate ligase hydrolase: thiouridine(34) (cytidine(1402)-2'-O) pseudouridine(38- 3-phosphate BBUJD1_RS02820 phosphopantothenate--cysteine di-trans,octa-cis- glucosamine-enolpyruvate ala acid--CoA ligase: BBUJD1_RS02070 BBUJD1_RS03105 form scaffold 5'-methylthioadenosine/ pyridoxal kinase: pyridoxal kinase: acetate kinase: long-chain fatty acid--CoA long-chain fatty acid--CoA BBUJD1_RS04765 acyltransferase: (NAD(+)) BBUJD1_RS05545 synthase MnmA: -methyltransferase: 40) synthase TruA: acyltransferase: endopeptidase La: ligase CoaBC: BBUJD1_RS05670 undecaprenyl phosphate alanine--tRNA ligase: BBUJD1_RS04530 an N-terminal L- protein] complex adenosylhomocysteine BBUJD1_RS05440 BBUJD1_RS05440 UDP-N- BBUJD1_RS04700 ligase: BBUJD1_RS04530 ligase: BBUJD1_RS02230 a double strandedBBUJD1_RS04770 DNA BBUJD1_RS03180 LigA: ligA an N-modified an uncharged met BBUJD1_RS05010 a 2'-O- BBUJD1_RS03700 BBUJD1_RS01615 BBUJD1_RS03180 BBUJD1_RS04645 [cysteine desulfurase]-S- BBUJD1_RS02650 an L-alanyl- 6-phosphofructokinase: Amine and Polyamine Degradation threonyl-[protein] a 5-methylaminomethyl- NADP + acetylenolpyruvoylglucosamine long-chain fatty amino acid tRNA 1402 [+ 3 isozymes] sulfanylcysteine:[acceptor nucleosidase: 4'-phosphopantetheine [tRNA Ala ] with a RecA protein 1-acyl-sn-glycerol- 34 methylcytidine 38- a peptide pyridoxal pyridoxine pyridoxamine reductase: BBUJD1_RS04555 BBUJD1_RS05235 acetate AMP diphosphate (2E)-hexadecenoyl-CoA AMP diphosphate lauroyl-CoA acid--CoA ligase: NMN AMP [DNA] 2-thiouridine in tRNA a pseudouridine 1-acyl-sn-glycerol- protein]-cysteine BBUJD1_RS03415 a tRNA Ala loaded 3' overhang 3-phosphate in 16S rRNA 3-phosphate pantetheine- 5'-phosphate 5'-phosphate superpathway of N-acetylglucosamine, BBUJD1_RS02230an odd numbered 40 in tRNA sulfurtransferase: [+ 2 isozymes] straight chain acyltransferase: acyltransferase: phosphate pyridoxal kinase: glu ala UDP-N-acetyl-α-D-muramate β-D-fructose 1,6- N-acetylmannosamine and N- diphosphate AMP BBUJD1_RS01965 S-ribosyl-L- 2,3,4-saturated BBUJD1_RS017401-palmitoyl- 1-palmitoyl-BBUJD1_RS01740 a [cysteine desulfurase]- adenylyltransferase: BBUJD1_RS05440 bisphosphate acetylneuraminate degradation homocysteine DHAP Pentose Phosphate Pathways fatty acyl CoA acyl-carrier protein 2-myristoyl 2-myristoyl S-sulfanyl-[disordered- BBUJD1_RS05105 glutamate racemase: N-acetylneuraminate UDP-N-acetylmuramate- asparagine-- class II fructose- Detoxification phosphatidate phosphatidate form scaffold S-ribosylhomocysteine 3'-dephospho- BBUJD1_RS02045 asn PLP thioredoxin pathway -L-alanine ligase: tRNA ligase: bisphosphate pentose phosphate protein] complex lyase: CoA BBUJD1_RS05690 BBUJD1_RS02050 triose-phosphate aldolase: pathway (oxidative branch) I reactive oxygen N-acetyl-D- BBUJD1_RS03425 an L-asparaginyl- a 2-methyl a tRNA precursor 1-cis-vaccenoyl- a 5,6- 2552 1498 cysteine desulfurase: dephospho- D-glt isomerase: BBUJD1_RS03785 3-oxo-(11Z)- uridine a uracil an oxidized α [tRNA Asn ] D-glucopyranose species degradation mannosamine 18-hydroxyoleate oleate a cis- an alkylated DNA F6P 20 BBUJD1_RS01965 CoA kinase: UDP-N-acetyl- -D-muramoyl-L-alanine BBUJD1_RS01825 branched 2,3,4- with a 5' sn-glycerol- VibB coenzyme A octadecenoyl-CoA dihydrouracil in 23S rRNA in 16S rRNA IPP L-homocysteine thioredoxin tRNA Asn 6-phosphate long-chain fatty acid--CoA long-chain fatty acid--CoA saturated fatty acid extension and a vaccenoyl-[acp] 3-phosphate DNA-3- acetyl-CoA C- diphosphate--fructose- in tRNA ribosomal RNA 16S rRNA an S-sulfanyl-[cysteine BBUJD1_RS04295 NADP + -dependent superoxide long-chain fatty 1-acyl-sn-glycerol- tRNA type 2 isopentenyl- ligase: BBUJD1_RS04530 ligase: BBUJD1_RS04530 short 3' extensionribonuclease P methyladenine holo-ACP synthase: acyltransferase: 6-phosphate 1- large subunit (uracil(1498)-N(3))- desulfurase]-S- S-adenosyl-L-methionine cycle I UDP-N-acetylmuramoyl- glucose-6-phosphate acid--CoA ligase: 3-phosphate dihydrouridine(20/ diphosphate coenzyme A D-glyceraldehyde N-acetyl-D- protein component: glycosylase: BBUJD1_RS01605 BBUJD1_RS02090 phosphotransferase: methyltransferase E: methyltransferase: sulfanyl-[disordered- L-alanine--D- dehydrogenase: superoxide long-chain fatty acid--CoA long-chain fatty acid--CoA BBUJD1_RS04530 acyltransferase: a holo-[VibB aryl- 20a) synthase DusA: Delta-isomerase: thioredoxin 3-phosphate mannosamine aBBUJD1_RS03765 tRNA precursor BBUJD1_RS03675 3',5'-ADP BBUJD1_RS01655 BBUJD1_RS03115 BBUJD1_RS01860 form scaffold glutamate ligase: BBUJD1_RS04780 dismutase [Fe]: ligase: BBUJD1_RS02230 ligase: BBUJD1_RS02230 long-chain fatty BBUJD1_RS03180 a DNA containing carrier protein] palmitoleoyl-CoA acetyl-CoA β BBUJD1_RS02675 a 2'-O- BBUJD1_RS05020 reductase: 6-phospho 6-phosphate a tRNA fragment with a short an alkylated -D-fructose 1,6- SAM BBUJD1_RS04490 aspartate-- glyceraldehyde- BBUJD1_RS02300 an apurinic/ 20 methyluridine 2552 16S rRNA DMAPP protein] complex BBUJD1_RS04145 asp D-glucono- N-acetylmannosamine- AMP diphosphate 18-hydroxyoleoyl-CoA diphosphate AMP oleoyl-CoA acid--CoA ligase: 1-acyl-sn-glycerol- bisphosphate a uracil in tRNA [cysteine desulfurase]-S- L-cystathionine tRNA ligase: 3-phosphate hydrogen 3' extension nucleobase apyrimidinic site in 23S rRNA (uracil(1498)-N(3))- meso-diaminopimelate UDP-N-acetyl-α-D-muramoyl- 1,5-lactone 6-phosphate BBUJD1_RS02230a 2-methyl 3-phosphate sulfanylcysteine:[acceptor BBUJD1_RS03790 an L-aspartyl- dehydrogenase: peroxide methyltransferase: L-alanyl-D-glutamate 6-phosphogluconolactonase: 2-epimerase: branched acyltransferase: protein]-cysteine S-adenosylmethionine asp BBUJD1_RS01835 AMP diphosphate BBUJD1_RS03330 [tRNA ] BBUJD1_RS04820 2,3,4-saturated BBUJD1_RS017401,2-dicis- an N 3 - sulfurtransferase: synthase: a reduced tRNA asp BBUJD1_RS02660 a sugar RS03140 a sugar N-acetyl-D- 1498 BBUJD1_RS01965 BBUJD1_RS03420 thioredoxin UDP-N-acetylmuramoyl- D-gluconate fatty acyl-CoA acyl-carrier protein vaccenoyl- methyluracil a [cysteine D-ala 13-DPG glucosamine L-alanyl-D- 6-phosphate phosphatidate in 16S rRNA desulfurase]-(S- cys 6-phosphate NAD de novo biosynthesis D-alanine--D- glutamate--2, 6- O H O hydroxyl radical sulfanyl) -[disordered- met SAH phosphogluconate 2 2 N-acetylglucosamine- a metal a metal 2 diaminopimelate ligase: phosphoglycerate RS04665 form scaffold I (from aspartate) 5'-methylthioadenosine/ alanine ligase: tyrosine-- dehydrogenase 6-phosphate a long-chain a carboxy- 1-palmitoyl- a double 3-oxo-(7Z)- an N-terminal- a 2'- 1-oleoyl-sn a [protein]-α- cation cation BBUJD1_RS02535 tyr kinase: 7-hydroxylaurate an (S)-2-halocarboxylate an apo-[aryl- protein] complex adenosylhomocysteine BBUJD1_RS02530 tRNA ligase: (NADP(+)- deacetylase: 2,3,4-saturated cys adenylated-[ThiS a palmitoyl-[acp] sn-glycerol stranded DNA coenzyme A tetradecenoyl-CoA L-methionyl-L- phosphoenol dADP deoxyribonucleoside -glycerol 3- L-glutamate BBUJD1_RS01830 long-chain fatty acid--CoA HAD family hydrolase: fatty acid sulfur-carrier protein] 3-phosphate exodeoxyribonuclease carrier protein] acetyl-CoA C- alanyl-[protein] pyruvate phosphate asp nucleosidase: D-alanyl-D-alanine UDP-N-acetyl-α-D-muramoyl-L-alanyl- BBUJD1_RS03390 an L-tyrosyl- dependent, BBUJD1_RS02290 long-chain fatty cysteine desulfurase: 1-acyl-sn-glycerol- holo-ACP synthase: methionine deoxynucleoside 1-acyl-sn-glycerol- chemotaxis protein decarboxylating): ligase: BBUJD1_RS04530 BBUJD1_RS04125 V: BBUJD1_RS04760 acyltransferase: pyruvate kinase: BBUJD1_RS03415 γ-D-glutamyl-meso-2,6-diaminopimelate [tRNA Tyr ] C1 Compound Utilization D-glucosamine acid--CoA ligase: BBUJD1_RS01965 3-phosphate BBUJD1_RS01605 aminopeptidase: kinase: 3-phosphate methyltransferase: 3-phospho-D-glycerate long-chain fatty acid--CoA HAD family hydrolase: BBUJD1_RS04765 BBUJD1_RS02090 BBUJD1_RS03285 L-cystine RS05245 L-cystine [+ 2 isozymes] a tRNA Tyr BBUJD1_RS04365 and Assimilation 6-phosphate BBUJD1_RS04530 acyltransferase: a holo-[aryl- BBUJD1_RS02070 BBUJD1_RS02745 BBUJD1_RS01755 a [cysteine desulfurase]- a thiocarboxy- BBUJD1_RS04770 3',5'-ADP (5Z)- an N-terminal L- a 2'- acyltransferase: a [protein]-L- 2-iminosuccinate UDP-N-acetylmuramoyl- D-ribulose ligase: BBUJD1_RS02230 BBUJD1_RS04980 AMP ala BBUJD1_RS03180 carrier protein] acetyl-CoA met [scaffold protein- long-chain fatty [ThiS-Protein] dodecenoyl-CoA dATP pyruvate BBUJD1_RS03180 5 tripeptide--D-alanyl- formate assimilation into 5,10- a halide anion a (2R)-2-hydroxy fatty acid a 5'-phosphooligonucleotide alanyl-[protein] deoxyribonucleoside glutamate-O (2Fe-2S)] complex L-homocysteine S-ribosyl-L-homocysteine 5-phosphate acid--CoA ligase: 1-acyl-sn-glycerol- D- alanine ligase: methylenetetrahydrofolate AMP diphosphate 7-hydroxylauroyl-CoA 5'-monophosphate 1-acyl-sn-glycerol- -methyl-ester BBUJD1_RS02230 3-phosphate 3-phosphate Na + RS05675 Na + BBUJD1_RS03075 α-D-glucosamine a long-chain tryptophan-- acyltransferase: acyltransferase: Trp formate 6-phosphate AMP diphosphate 2,3,4-saturated a tRNA BBUJD1_RS01740 a [co-chaperone]- UDP-N-acetyl-α-D-muramoyl-L- tRNA ligase: BBUJD1_RS01740 quinolinate S-ribosylhomocysteine 2-phospho-D-glycerate glucosamine- fatty acyl CoA dipalmitoyl dioleoyl [scaffold protein- alanyl-γ-D-glutamyl-meso-2,6- di-trans,octa-cis-undecaprenyl phosphate BBUJD1_RS01580 an L-tryptophanyl- acyl-carrier protein lyase: BBUJD1_RS03425 10 6-phosphate phosphatidate phosphatidate Trp an N - (2Fe-2S)] complex diaminopimeloyl-D-alanyl-D-alanine [tRNA ] deaminase: formyltetrahydrofolate trp enolase: BBUJD1_RS02295 BBUJD1_RS03230 bifunctional 5,10- a 2,3,4-saturated a single- (5Z,8Z,11Z,14Z,17Z) an N-terminal- α-linolenate an (R)-2-halocarboxylate coenzyme A an apo [peptidyl- [EntB aryl- 5-cis, 7-trans-3-oxo- DNA with lesion a [protein]- a [chaperone-ATP]- NaMN methylenetetrahydrofolate F6P fatty acid stranded RNA -icosapentaenoate coenzyme A coenzyme A L-methionyl- phosphoenol an acyl phosphate undecaprenyldiphospho- carrier protein] carrier protein] tetradecadienoyl-CoA dGDP L-glutamine [co-chaperone]- acyl carrier dehydrogenase/5,10- long-chain fatty acid--CoA HAD family hydrolase: long-chain fatty polyribonucleotide long-chain fatty acetyl-CoA C- glycyl-[protein] pyruvate excinuclease chemoreceptor nicotinate N-acetylmuramoyl-L-alanyl- Alcohol Degradation holo-ACP synthase: holo-ACP synthase: methionine [scaffold protein- protein activation Carbohydrate threonine-- phosphoenolpyruvate methenyltetrahydrofolate ligase: BBUJD1_RS02230 BBUJD1_RS04125 acid--CoA ligase: nucleotidyltransferase: acid--CoA ligase: acyltransferase: pyruvate kinase: acylphosphatase: ABC subunit C: glutamine (nicotinamide) γ-D-glutamyl-meso-2,6- thr BBUJD1_RS01605 BBUJD1_RS01605 aminopeptidase: (2Fe-2S)] complex Biosynthesis tRNA ligase: cyclohydrolase: long-chain fatty acid--CoA HAD family hydrolase: BBUJD1_RS02230 BBUJD1_RS05635 BBUJD1_RS02230 BBUJD1_RS02090 BBUJD1_RS02070 BBUJD1_RS03285 BBUJD1_RS06245 BBUJD1_RS03845 deamidase CheD: nucleotide an apo acyl- diaminopimeloyl-D-alanyl-D-alanine glycerol degradation I a nucleoside a single- a holo [peptidyl- a holo-[EntB aryl- (3Z,5E)-dodeca- BBUJD1_RS05200 an L-threonyl- BBUJD1_RS01685 ligase: BBUJD1_RS04530 BBUJD1_RS04980 long-chain fatty long-chain fatty 3',5'-ADP 3',5'-ADP acetyl-CoA an N-terminal excinuclease ABC: BBUJD1_RS04595 adenylyltransferase: carrier protein UDP-α-D-glucose undecaprenyldiphospho- pyruvate kinase: diphosphate stranded RNA carrier protein] carrier protein] 3,5-dienoyl-CoA met dGTP pyruvate a [protein]-α- Thr a 5,10- a halide anion a (2R)-2-hydroxy fatty acid acid--CoA ligase: acid--CoA ligase: glycyl-[protein] a carboxylate BBUJD1_RS05780 BBUJD1_RS05515 holo-ACP synthase: biosynthesis I [tRNA ] BBUJD1_RS03285 α L-glutamate muramoylpentapeptide beta-N- Thr glycerol AMP diphosphate -linolenoyl-CoA BBUJD1_RS04530 BBUJD1_RS01605 a tRNA methenyltetrahydrofolate BBUJD1_RS04530 BBUJD1_RS05785 nicotinate adenine D-glucopyranose acetylglucosaminyltransferase: (5Z,8Z,11Z,14Z,17Z) DNA without a [chaperone- a holo acyl- bifunctional 5,10- glycerol kinase: a 2,3,4-saturated an [2Fe-2S] dinucleotide 6-phosphate BBUJD1_RS05435 AMP diphosphate -icosapentaenoyl-CoA lesion ADP]-[disordered- carrier protein pyruvate methylenetetrahydrofolate BBUJD1_RS02755 fatty acyl CoA cluster protein form scaffold NAD+ synthetase, phosphoglucomutase: sn-glycerol NAD(+) synthase: BBUJD1_RS01575 lipid II (meso diaminopimelate containing) dehydrogenase/5,10- protein] complex glutamine α-D-glucopyranose 3-phosphate BBUJD1_RS04170 methenyltetrahydrofolate dependent: 1-phosphate ser serine--tRNA ligase: cyclohydrolase: an apo-[LYS2 L- a peptide with an insertion BBUJD1_RS04170 PRPP biosynthesis 10 an L-methionyl- (6Z,9Z,12Z,15Z,18Z)-3- phosphoenol an [HPr]- 2-methylacetoacetyl- (R)-mevalonate UTP--glucose- BBUJD1_RS02680 BBUJD1_RS01685 pristanate an N - [EntF L-seryl- (R)-pantothenate propanoate an L-seryl- Met oxotetracosapentaenoyl-CoA pyruvate L-histidine 2-aminoadipyl- coenzyme A coenzyme A CoA an N-terminal sequence + formyltetrahydrofolate [initiator tRNA ] a tRNA precursor CTP ATP diphosphate an [Fe-S cluster a [disordered- NAD 1-phosphate Secondary Metabolite Biosynthesis ser carrier protein] D-ribose 5- [tRNA ] a 5,10- long-chain fatty acid--CoA methionyl-tRNA acetyl-CoA C- phosphoenolpyruvate- carrier-protein] acetyl-CoA C- type III pantothenate L-methioninemethionine element IS30transposase: ser DHAP holo-ACP synthase: holo-ACP synthase: diphosphomevalonate acetate kinase: biosynthesis form [Fe-S] cluster uridylyltransferase: phosphate a tRNA methylenetetrahydrofolate ligase: BBUJD1_RS04530 formyltransferase: CCA tRNA acyltransferase: -protein acyltransferase: kinase: aminopeptidase: phosphoribosylpyrophosphate BBUJD1_RS01605 BBUJD1_RS01605 decarboxylase: BBUJD1_RS08145 BBUJD1_RS04700 chaperone]-ATP scaffold protein] BBUJD1_RS01570 autoinducer AI-2 biosynthesis I long-chain fatty acid--CoA BBUJD1_RS01870 nucleotidyltransferase: BBUJD1_RS02090 phosphotransferase: a holo-[LYS2 L- a holo-[EntF BBUJD1_RS02090 BBUJD1_RS04190 BBUJD1_RS02070 synthetase: BBUJD1_RS04280 an N-formyl- a tRNA BBUJD1_RS05125 (4Z,7Z,10Z,13Z,16Z)- BBUJD1_RS05030 transposase: UTP--glucose- ligase: BBUJD1_RS02230 acetyl-CoA BBUJD1_RS04350 2-aminoadipyl- 3',5'-ADP 3',5'-ADP L-seryl-carrier acetyl-CoA propanoyl-CoA (R)-4'- PRPP L-methionyl- a tetrahydrofolate containing a docosapentaenoyl-CoA an [HPr protein]- a peptide met an insertionBBUJD1_RS06105 propanoyl 1-phosphate met π carrier-protein] protein] IPP [initiator tRNA ] N -phospho- pyruvate phosphopantothenate sequence IS30 phosphate uridylyltransferase: SAM AMP diphosphate pristanoyl-CoA 3' CCA end L-histidine with integrated BBUJD1_RS02580 pro proline--tRNA ligase: transposon UDP-α-D-glucose BBUJD1_RS03560 an L-prolyl- Pro SAH [tRNA ] (5E)-3-oxo- Amino Acid Biosynthesis Pro β a 2,3,4-saturated a peptide with a tRNA 5-phospho- - quinoxaline-2- 3-(4-hydroxyphenyl)- an unsulfurated 3-oxopentanoyl- D-sedoheptulose an L-cysteinyl- palmitate aryl-carrier protein CTP 1,2-diacyl-sn- an N-terminal cys dodec-5- DHAP DHAP 5'-methylthioadenosine/ D-ribosylamine carboxyl adenylate 3-oxo-propanoyl-CoA CoA 1-phosphate [tRNA Cys ] long-chain fatty acid--CoA acetyl-CoA C- glycerol 3-phosphate [sulfur carrier] acetyl-CoA C- enoyl-CoA class II fructose- NAD(P)H- L-alanine adenosylhomocysteine acyl carrier protein: phosphatidate Xaa-L-prolineaminopeptidase: cysteine desulfurase: acetyl-CoA C- aminoacyl-tRNA methylglyoxal glycine biosynthesis I ligase: BBUJD1_RS04530 amidophosphoribosyltransferase: acyltransferase: acyltransferase: bisphosphate dependent glycerol- biosynthesis III nucleosidase: BBUJD1_RS05115 cytidylyltransferase: BBUJD1_RS03370 BBUJD1_RS01965 acyltransferase: hydrolase: synthase: BBUJD1_RS05600 BBUJD1_RS02090 a peptide with BBUJD1_RS02090 aldolase: 3-phosphate BBUJD1_RS03415 long-chain fatty acid--CoA a quinoxaline-2- BBUJD1_RS02140 a proteinogenic a sulfurated BBUJD1_RS02090 BBUJD1_RS05545 BBUJD1_RS03360 phenylalanine-- a CDP-2,3,4-saturated- an N-terminal ala (3E)-dec-3- BBUJD1_RS03785 dehydrogenase: phe ligase: BBUJD1_RS02230 AMP carboxyl-[aryl- acetyl-CoA 4-hydroxybenzoyl-CoA propanoyl-CoA acetyl-CoA Cys cys ser [+ 2 isozymes] PRPP amino acid [sulfur carrier] acetyl-CoA a tRNA cys methylglyoxal tRNA ligase: pheS carrier protein] diacylglycerol L-proline enoyl-CoA D-erythrose DHAP BBUJD1_RS03380 cysteine desulfurase: serine S-ribosyl-L-homocysteine BBUJD1_RS04140 an L-phenylalanyl- AMP diphosphate palmitoyl-CoA sn-glycerol BBUJD1_RS01965 hydroxymethyltransferase: glyA [tRNA Phe ] 3-phosphate Phe ala gly S-ribosylhomocysteine a tRNA lyase: an N-formyl-L- a long-linear 4-trans-3-oxo- (R)-5- 3,22-dioxochol- phosphoenol BBUJD1_RS03425 phytenate α-D-glucopyranose a [ThiI sulfur-carrier coenzyme A NADP + AsbD acyl- octanoyl-CoA acetyl-CoA DL-allothreonine methionylaminoacyl- α-D-glucan cys coenzyme A undecenoyl-CoA phosphomevalonate 4-en-24-oyl-CoA a protein pyruvate long-chain fatty acid--CoA 4-alpha- protein]-L-cysteine CoA-disulfide carrier protein acetyl-CoA C- acetyl-CoA C- AI-2 tRNA peptide deformylase: phosphomevalonate acetyl-CoA C- methionine-- ligase: BBUJD1_RS02230 serine glucanotransferase: cysteine desulfurase: reductase: holo-ACP synthase: acyltransferase: acyltransferase: HslU--HslV peptidase pyruvate kinase: met hydroxymethyltransferase: glyA BBUJD1_RS01875 BBUJD1_RS01965 BBUJD1_RS01605 kinase: acyltransferase: tRNA ligase: long-chain fatty acid--CoA BBUJD1_RS02365 a [ThiI sulfur- BBUJD1_RS05240 BBUJD1_RS02090 BBUJD1_RS02090 ATPase subunit: BBUJD1_RS03285 BBUJD1_RS04500 an L-methionyl- a L-methionylaminoacyl- a short 1,4- a holo-[AsbD acyl- 2-trans- 3-oxodecanoyl- BBUJD1_RS05035 BBUJD1_RS02090 gly acetaldehyde formate carrier protein]-S- ala + 3',5'-ADP BBUJD1_RS03030 [elongator ligase: BBUJD1_RS04530 tRNA α-D-glucan H NADPH CoA-disulfide carrier protein] acetyl-CoA (R)-mevalonate 3-oxo-4-pregnene- sulfanyl-L-cysteine nonenoyl-CoA CoA pyruvate (2R,4S)-2-methyl-2,4- elongator tRNA Met ] diphosphate 20-carboxyl-CoA a peptide Met diphosphate AMP phytenoyl-CoA dihydroxydihydrofuran-3-one tRNA

undecaprenyl-diphospho-N 5-amino-4- a 2-deoxy-D- 3-oxo-(9Z)- 3-oxo-(9Z)- 3-oxo-(5Z)- a [protein]-L- a nucleoside (2R,4S)-2-methyl-2,3,3,4- Lys PRPP a nucleobase maltopentaose D-glucopyranose nicotinate PRPP a uracil in DNA a uridine in tRNA pyrazinamide a tRNA -acetylmuramoyl-L-alanyl-γ- UDP-N-acetyl-α-D-glucosamine imidazolecarboxyamide ribosyl-base octadecenoyl-CoA hexadecenoyl-CoA tetradecenoyl-CoA proline (ω = 180) tetrahydroxytetrahydrofuran lysine--tRNA ligase: 4-alpha- diphosphate D-glutamyl-L-lysyl- D-alanine undecaprenyldiphospho- adenine nucleoside nicotinate acetyl-CoA C- acetyl-CoA C- uracil-DNA acetyl-CoA C- tRNA-dihydrouridine peptidyl-prolyl cis- BBUJD1_RS04895 an L-lysyl- glucanotransferase: nucleoside- muramoylpentapeptide beta-N- phosphoribosyltransferase: deoxyribosyltransferase: phosphoribosyltransferase: acyltransferase: acyltransferase: glycosylase: acyltransferase: synthase: trans isomerase: pyrazinamidase: [tRNA Lys ] BBUJD1_RS05490 BBUJD1_RS03695 BBUJD1_RS02365 BBUJD1_RS04775 BBUJD1_RS02090 BBUJD1_RS02090 BBUJD1_RS01815 BBUJD1_RS02090 diphosphate kinase: BBUJD1_RS00685 acetylglucosaminyltransferase: a 2-deoxy-D- (7Z)- (7Z)- an apyrimidinic (3Z)-dodec- BBUJD1_RS05280 BBUJD1_RS01750 BBUJD1_RS03895 lys AICAR a nucleobase maltose maltotetraose NaMN acetyl-CoA acetyl-CoA uracil acetyl-CoA ditrans,octacis-undecaprenyldiphospho-BBUJD1_RS05435 ribosyl-base hexadecenoyl-CoA tetradecenoyl-CoA site in DNA 3-enoyl-CoA a 5,6-dihydrouridine a [protein]-L- a nucleoside pyrazine-2- ω UDP N-acetyl-(N-acetylglucosaminyl)muramoyl- in tRNA proline ( = 0) triphosphate carboxylate L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

his histidine-- tRNA ligase: decaprenyl-diphospho-N- UDP-N-acetyl- 3-oxo-2-(cis-2'-pentenyl)- 3-oxo-2-(cis-2'-pentenyl)- 7-carboxy-4-methyl-3,5- 3-oxo-(7Z)- 6-trans-3-oxo- 3-oxododecanoyl- 3-oxo- a double a supercoiled D-ribose 5- α maltohexaose maltose (R)-mevalonate BBUJD1_RS02220 an L-histidyl- acetylmuramoyl-pentapeptide -D-glucosamine cyclopentane-1-(3-oxooctanoyl)-CoA cyclopentane-1-(3-oxobutanoyl)-CoA dioxoheptanoyl-CoA hexadecenoyl-CoA tridecenoyl-CoA CoA myristoyl-CoA stranded DNA duplex DNA phosphate undecaprenyldiphospho- acetyl-CoA C- acetyl-CoA C- 4-alpha- acetyl-CoA C- acetyl-CoA C- acetyl-CoA C- acetyl-CoA C- acetyl-CoA C- His DNA gyrase: replicative ribose-5-phosphate [tRNA ] muramoylpentapeptide beta-N- glucanotransferase: mevalonate kinase: a tRNA His acyltransferase: acyltransferase: acyltransferase: acyltransferase: acyltransferase: acyltransferase: acyltransferase: BBUJD1_RS03735 DNA helicase: isomerase: acetylglucosaminyltransferase: BBUJD1_RS02090 BBUJD1_RS02090 BBUJD1_RS02365 BBUJD1_RS02090 BBUJD1_RS02090 BBUJD1_RS02090 BBUJD1_RS02090 BBUJD1_RS02090 BBUJD1_RS05040 3-oxo-2-(cis-2'-pentenyl)- 5-carboxy-2-methyl- (5Z)- 4-trans- BBUJD1_RS03740 BBUJD1_RS02100 BBUJD1_RS04885 BBUJD1_RS05435 acetyl-CoA acetyl-CoA (+)-7-epi-jasmonoyl-CoA D-glucopyranose maltoheptaose acetyl-CoA acetyl-CoA acetyl-CoA acetyl-CoA decanoyl-CoA acetyl-CoA lauroyl-CoA decaprenyl-pyrophosphoryl- cyclopentane-1-hexanoyl-CoA 3-oxopentanoyl-CoA tetradecenoyl-CoA undecenoyl-CoA (R)-5- a negatively a single D-ribulose UDP (N-acetylglucosamine)-N- phosphomevalonate supercoiled DNA stranded DNA 5-phosphate acetylmuramyl-(pentapeptide) gly glycine--tRNA ligase: BBUJD1_RS03395 a plant soluble a DNA containing Gly 3-oxo-2-(cis-2'-pentenyl)- (6Z,9Z,12Z,15Z,18Z,21Z)-3- D-glucopyranose 9-carboxy-6-methyl-3,7- 6-cis, 3-oxo- 3-oxooctanoyl- a cytidine 34 a glycyl-[tRNA ] an (R)-2-halocarboxylate heteroglycan an apurinic/ a 3-oxoacyl-CoA lys acetyl-CoA xylitol L-arabinitol cyclopentane-1-(3-oxohexanoyl)-CoA oxotetracosahexaenoyl-CoA dioxononanoyl-CoA tridecenoyl-CoA CoA in tRNA Ile2 a tRNA Gly HAD family hydrolase: acetyl-CoA C- acetyl-CoA C- 4-alpha- acetyl-CoA C- apyrimidinic site acetyl-CoA C- acetyl-CoA C- acetyl-CoA C- glucanotransferase: endonuclease III: tRNA(Ile)-lysidine acetyl-CoA C- aldose reductase: aldose reductase: BBUJD1_RS04125 acyltransferase: acyltransferase: acyltransferase: acyltransferase: acyltransferase: acyltransferase: synthetase: acyltransferase: BBUJD1_RS02090 BBUJD1_RS02090 BBUJD1_RS02365 BBUJD1_RS02090 BBUJD1_RS05330 BBUJD1_RS02090 BBUJD1_RS02090 BBUJD1_RS02090 BBUJD1_RS04195 BBUJD1_RS04195 HAD family hydrolase: a plant soluble a 3'-terminal a 5'-phospho- BBUJD1_RS05550 BBUJD1_RS02090 3-oxo-2-(cis-2'-pentenyl)- (4Z,7Z,10Z,13Z,16Z,19Z) maltose 7-carboxy-4-methyl- 4-cis- a lysidine 34 aldehydo-L- BBUJD1_RS04980 acetyl-CoA acetyl-CoA heteroglycan acetyl-CoA unsaturated sugar [DNA] acetyl-CoA acetyl-CoA hexanoyl-CoA acetyl-CoA an acyl-CoA D-xylopyranose cyclopentane-1-butanoyl-CoA -docosahexaenoyl-CoA 5-oxoheptanoyl-CoA undecenoyl-CoA in tRNA Ile2 acetoacetyl-CoA arabinose methionine-- a halide anion an (S)-2-hydroxycarboxylate met tRNA ligase: BBUJD1_RS04500 an L-methionyl- Met a 2,3,4-saturated 3-oxo-(5Z)- [initiator tRNA ] an (S)-2-halocarboxylate acetoacetyl-CoA H O acetyl-CoA a peptidoglycan maltohexaose D-glucopyranose [DNA] a single a ribonucleoside butanoyl-CoA acetyl-CoA an α-limit dextrin L-arabinitol a sugar alcohol D-mannitol initiator tRNA Met 2 3-oxoacyl-CoA dodecenoyl-CoA 4-alpha- stranded DNA triphosphate HAD family hydrolase: hydroxymethylglutaryl- muramidase: exodeoxyribonuclease DNA primase: acetyl-CoA C- acetyl-CoA C- acetyl-CoA C- 4-alpha- BBUJD1_RS04125 CoA synthase: BBUJD1_RS05460 glucanotransferase: III: BBUJD1_RS04220 acyltransferase: acyltransferase: acyltransferase: glucanotransferase: aldose reductase: aldose reductase: aldose reductase: a N-acetylmuramoyl- a 2'- BBUJD1_RS05155 HAD family hydrolase: BBUJD1_RS05015 N-acetyl-D- BBUJD1_RS02365 ssDNA/pppN(pN) BBUJD1_RS02090 BBUJD1_RS02090 BBUJD1_RS02090 BBUJD1_RS02365 BBUJD1_RS04195 BBUJD1_RS04195 BBUJD1_RS04195 pentapeptide- deoxyribonucleoside [DNA] a 2,3,4-saturated 3-oxohexanoyl- (3Z)-dec-3- BBUJD1_RS04980 HMG-CoA glucosamine maltose maltopentaose hybrid acetyl-CoA acetyl-CoA a α-limit dextrin aldehydo- diphosphoundecaprenol 5'-monophosphate n -1 fatty acyl CoA CoA enoyl-CoA L-arabinopyranose an aldose a halide anion an (S)-2-hydroxycarboxylate with short branches D-mannose

UDP-N-acetyl-α-D-muramoyl- RNase III mRNA a 5S rRNA a [protein] N-terminal- 3-oxo- 2'-deoxycytidine uridine maltotetraose D-glucopyranose a maltodextrin D-glucopyranose a glucan maltotriose 2+ galactitol γ D-alanyl-D-alanine protoporphyrin IX Mg a tRNA sec ser L-alanyl- -D-glutamyl-L-lysine processing substrate precursor formyl-L-methionine palmitoyl-CoA deoxynucleoside ribonuclease 3: ribonuclease M5: 4-alpha- 4-alpha- peptide deformylase: 4-alpha- acetyl-CoA C- Mg chelatase: uridine kinase: UDP-N-acetylmuramoyl- serine--tRNA ligase: aldose reductase: kinase: tripeptide--D-alanyl- BBUJD1_RS05120 BBUJD1_RS07965 glucanotransferase: glucanotransferase: BBUJD1_RS01875 glucanotransferase: acyltransferase: BBUJD1_RS01975 BBUJD1_RS01630 RNase III processing a double-stranded BBUJD1_RS02365 BBUJD1_RS02365 an N-terminal L- BBUJD1_RS02365 Mg- BBUJD1_RS02680 BBUJD1_RS04195 BBUJD1_RS02745 D- alanine ligase: an mRNA fragment a mature 5S-rRNA formate BBUJD1_RS02090 an L-seryl- product mRNA oligonucleotide methionyl-[protein] protoporphyrin dCMP UMP BBUJD1_RS03075 maltose maltotriose maltose a maltodextrin D-glucopyranose a glucan myristoyl-CoA acetyl-CoA sec UDP-N-acetyl-α-D-muramoyl-L-alanyl- [tRNA ] D-galactopyranose γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

a dicarboxylate putrescine D-cellobiose spermidine glycine betaine glycine betaine D-mannose an amino D-fructose D-fructose D-glucose 6- D-glucose 6- D-cellobiose 6'-phosphate an a sugar 6- cis-vaccenoyl-CoA cis-vaccenoyl-CoA (S)-lactate 6'- chromate chromate a nucleotide pro gly 6-phosphate acid 1-phosphate 1-phosphate phosphate phosphate lactose 6'-phosphate oligopeptide phosphate a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA phosphate a lipopolysaccharide predicted ATP-driven RS02275 RS02265 RS02125 RS04585 RS03555 RS07945 RS04740 RS06260 RS03815 RS03820 RS06370 RS04825 RS06265 RS03910 RS04165 RS03220 transporter RS06270 RS04530 RS02230 of spermidine/ D-cellobiose putrescine glycine betaine glycine betaine D-mannose (S)-lactate D-fructose D-fructose D-cellobiose chromate chromate D-glucose D-glucose a nucleotide an a sugar cis-vaccenate cis-vaccenate pro gly an amino lactose a lipopolysaccharide oligopeptide a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid acid putrescine spermidine a dicarboxylate This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.