Authors: Pallavi Subhraveti Ron Caspi Quang Ong Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_001436645Cyc: Lactobacillus florum DSM 22689 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari glutamate glutamate 4-aminobutanoate 4-aminobutanoate 4-aminobutanoate

RS05160 RS04600 RS03570 RS02660 RS05985 RS04845 RS03090 RS04815 RS01865 RS01140 RS04595 RS05295 RS03130 RS02035 RS00750 RS04460 RS02585 RS03240 RS03775 RS01490 RS03970 RS01010 RS00540 RS01295 RS03560 RS00950 RS00060 RS01685 RS02920 RS04720 RS00865 RS04440 RS00220 RS05590 RS01850 RS02420 RS06185 RS04555 RS01395 RS02125 RS05105 RS05320 RS00100 RS03700 RS00105 RS01815 RS02655 RS05780 RS04050 RS06120 RS03265 RS03645 RS04810 RS01050 RS03375 RS01380 RS06145 RS04515

glutamate glutamate 4-aminobutanoate 4-aminobutanoate 4-aminobutanoate

C1 Compound Utilization and Assimilation Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis Fermentation a ribonucleoside a 1-acyl-sn formaldehyde assimilation II (assimilatory RuMP Cycle) a glycopeptide- 1-stearoyl- 2-keto-D- 4 [EntF L-seryl- a [protein] Ser/Thr a ribonucleoside thiamine salvage II 10 Amino Acid Degradation D-mannosyl-N coenzyme A a palmitoyl-[acp] sn-glycerol a protein 2',3'-cyclic -glycerol 3- L-cysteine biosynthesis N -formyl-tetrahydrofolate biosynthesis di-trans,poly-cis NAD phosphorylation citrate lyase activation heterolactic fermentation carrier protein] diphosphate XMP IMP gluconate dGDP glutathione- -(N-acetyl-D- phosphate serine/threonine phosphate 2,5-diketo-D- VI (from L-methionine) and dephosphorylation Aminoacyl-tRNA Charging D-ribulose holo-ACP 1-acyl-sn-glycerol-3-phosphate Clp protease ClpX: ribonucleoside- 1-acyl-sn-glycerol- -undecaprenyl glutaredoxin F6P multifunctional 2',3'- multifunctional 2',3'- ribonucleoside- 4-amino-2-methyl-5- formaldehyde L-tryptophan glucosaminyl) synthase CitX: 3-phosphate FC87_RS05025 protein kinase: diphosphate multifunctional 2',3'- 3-phosphate gluconic acid phosphate biosynthesis redox reactions 3'-dephospho- β-D-fructofuranose 5-phosphate L-glutamine mannosyl-glycoprotein cyclic-nucleotide 2'- predicted pyrimidinemethanol a tetrahydrofolate + -asparagine FC87_RS05220 cyclic-nucleotide 2'- cyclic-nucleotide 2'- reductase: diphosphate degradation IV (via 2 FC87_RS04245 acyltransferase: reductase acyltransferase: predicted met (2E,6E)-farnesyl NAD CoA tRNA charging 3-hexulose- degradation I endo-beta-N- ATP-dependent phosphodiesterase/ ABC gln phosphodiesterase/ phosphodiesterase/ FC87_RS02150 reductase bifunctional IPP GSSG glutaminyl-tRNA indole-3-lactate) phosphopantetheinyl FC87_RS03650 Clp protease HPr kinase/ subunit alpha: FC87_RS03650 ABC methionine diphosphate triphosphoribosyl- 6-phosphate acetylglucosamidase: 1-stearoyl- 5'-nucleotidase/ a 1-acyl-2- 5'-nucleotidase/ subunit alpha: gln met transporter met hydroxymethylpyrimidine isoprenyl glutathione biosynthesis via fructokinase: phosphorylase: FC87_RS00905 5'-nucleotidase/ 2,5-diketo-D- gln transporter adenosyltransferase: dephospho-CoA synthase: β FC87_RS04785 transferase: 2-palmitoyl- proteolytic subunit: 3'-nucleotidase: palmitoyl-sn FC87_RS00905 of L- kinase/ transferase: alkaline reductase: arginine-- transamidation FC87_RS00510 -D-fructose 1,6- trp gln acyl-carrier protein FC87_RS00745 3'-nucleotidase: 3'-nucleotidase: FC87_RS03565 synthase CitG: arg FC87_RS01540 sn-glycerol FC87_RS00690 FC87_RS02985 ribonucleoside- -glycerol 3- gluconic acid of L-glutamine methionine di-trans,octa-cisFC87_RS03690 NAD kinase: FC87_RS06200 tRNA ligase: FC87_RS04345 bisphosphate asparagine mannosyl-glycoprotein a holo-[EntF FC87_RS02985 FC87_RS02985 ribonucleoside- phosphomethylpyrimidine phosphatase: aromatic amino acid a ribonucleoside a [protein] (L-serine/L- phosphate reductase: SAM FC87_RS03070 FC87_RS04250 FC87_RS02605 D-glucopyranose endo-beta-N- 3',5'-ADP L-seryl-carrier 3-phosphate a peptide a peptide diphosphate cys RS03550 cys kinase: FC87_RS05515 -undecaprenyl FC87_RS06040 glutathione 2'-(5''-triphospho- an L-arginyl- Glu F6P hexulose 6- aminotransferase: synthase 3'-phosphate threonine) phosphate [+ 2 isozymes] [+ 2 isozymes] FC87_RS02705 diphosphate Gln reductase: dihydrofolate Arg glutamyl-tRNA (glutamine- acetylglucosamidase: protein] 2,5-didehydro- hydroxymethylpyrimidine/ diphosphate α-D-ribosyl)-3'- [tRNA ] phosphate fructose- FC87_RS05065 a glycopeptide- xanthosine inosine reductase: RS05150 Arg synthetase: N-acetyl-D-FC87_RS06020 a 2'- FC87_RS00910 phosphomethylpyrimidine reductase: dephospho-CoA a tRNA bisphosphate aromatic amino acid hydrolyzing): D-gluconate FC87_RS00910 + glucokinase: 6-phospho-3- D-mannosyl- FC87_RS04015 NADP FC87_RS00980 glucose-6- aldolase: FC87_RS05365 glucosamine- deoxyribonucleoside kinase: FC87_RS01420 apo-citrate lyase an L-glutamyl- FC87_RS02360 aminotransferase: N 4 -N-acetyl- GDP serine phosphate hexuloisomerase: asparagine 5'-diphosphate RS02960 a 7,8-dihydrofolate a 5-methyltetrahydrofolate a reduced phosphoribosyl- [tRNA Gln ] FC87_RS02130 FC87_RS03530 [+ 5 isozymes] D-glucosamine SAH hydroxymethyltransferase: glyA di-trans,octa-cis- isomerase: FC87_RS04340 (indol-3- HMP-P glutaredoxin dephospho-CoA Glu undecaprenyl phosphate folate transformations I S-adenosyl-L-methionine cycle I aspartyl/ D-glyceraldehyde yl)pyruvate transferase: cysteine-- pgi F6P 5'-methylthioadenosine/ thymidylate cys glutamyl-tRNA DHAP RS00280 bifunctional formate-- 3-phosphate undecaprenyl- 1-stearoyl- DNA combined with guanosine a uracil 1939 a negatively a [protein]- synthase: bifunctional a (6S)-5- FC87_RS04245 tRNA ligase: amidotransferase NMN a [glycerolipid]- hydroxymethylpyrimidine S-adenosylhomocysteine tetrahydrofolate diphospho-N- VibB coenzyme A a stearoyl-[acp] sn-glycerol exogenous DNA to form 2',3'-cyclic in 23S rRNA supercoiled DNA L-tyrosine FC87_RS04010 methylenetetrahydrofolate a holo [citrate SAM FC87_RS00975 an L-cysteinyl- GMP oleate dADP kinase/ nucleosidase: formyltetrahydrofolate subunit B: a recombinational junction monophosphate bifunctional 23S rRNA (uracil-5- cyclopropane- DNA phosphate ligase: two reduced lyase acyl- Cys acetylmuramoyl- UDP-N-acetyl- holo-ACP 1-acyl-sn-glycerol-3-phosphate Holliday junction RS06050 FC87_RS03185 dehydrogenase/ 5-formyltetrahydrofolate [tRNA ] FC87_RS04750 D-glucopyranose indole-3-lactate multifunctional 2',3'- protein-tyrosine- ribonucleoside- 5-(2-hydroxyethyl) phosphomethylpyrimidine Cys L-alanyl-γ-D- α-D-glucosamine metallophosphatase/ )-methyltransferase multifunctional 2',3'- fatty-acyl- topoisomerase a tetrahydrofolate FC87_RS02030 cysteine residues carrier protein] a tRNA 6-phosphate synthase CitX: 3-phosphate resolvase RuvX: cyclic-nucleotide 2'- phosphatase: kinase: FC87_RS05515 methenyltetrahydrofolate cyclo-ligase: methionine [+ 2 isozymes] undecaprenyldiphospho- 5'-nucleotidase: RumA: cyclic-nucleotide 2'- diphosphate -4-methylthiazole S-ribosyl-L- 10 in a protein [citrate (pro-3S) D-erythrose D-xylulose glutamyl-L-lysyl- FC87_RS04245 acyltransferase: FC87_RS00150 phospholipid IV subunit B: biotin RS04410 biotin cyclohydrolase: FC87_RS02375 an N - + phosphodiesterase/ FC87_RS05850 hydroxymethylpyrimidine/ homocysteine adenosyltransferase: an L-glutaminyl- NADP -dependent 4-phosphate 5-phosphate D-alanyl-D-alanine muramoylpentapeptide beta-N- FC87_RS06255 FC87_RS04740 phosphodiesterase/ synthase: FC87_RS01895 reductase hydroxyethylthiazole FC87_RS02305 formyltetrahydrofolate -lyase] ligase: ditrans,octacis- phosphopantetheinyl FC87_RS036501-stearoyl-2- Holliday junction 5'-nucleotidase/ a 5,10- a 5,10- FC87_RS03565 Gln glucose-6- acetylglucosaminyltransferase: 5'-nucleotidase/ FC87_RS01840 protein-tyrosine- subunit alpha: kinase: FC87_RS01430 phosphomethylpyrimidine FC87_RS04225 [tRNA ] undecaprenyldiphospho- transferase: 3'-nucleotidase: 1-(β-D [+ 2 isozymes] 23S rRNA (uracil-5- DNA methylenetetrahydrofolate methenyltetrahydrofolate phosphate FC87_RS03125 stearoyl-sn resolvase 3'-nucleotidase: a [phospholipid]- phosphatase: FC87_RS00905 kinase: FC87_RS01420 thiamine diphosphate an acetyl-holo β acyl-carrier protein )-methyltransferase topoisomerase 4-methyl-5-(2- met SAH dehydrogenase: Detoxification N-acetyl-(N-acetyl- -D- FC87_RS01540 -glycerol 3- resolution of recombinationalRecU: recU FC87_RS02985 ribofuranosyl) dihydrosterculate FC87_RS05550 RS03085 biosynthesis I (E. coli) bifunctional [citrate lyase acyl- gln UDP a holo-[VibB aryl- RumA: FC87_RS02985 IV subunit A: a [protein]- ribonucleoside- phosphooxyethyl) HMP-PP FC87_RS01185 glucosaminyl)muramoyl- 3',5'-ADP phosphate junction formation 3'-GMP nicotinamide RS03510 methylenetetrahydrofolate 5'-methylthioadenosine/ carrier protein] FC87_RS05615 [+ 2 isozymes] FC87_RS01900 L-tyrosine diphosphate thiazole 2-[(2R,5Z)- bifunctional carrier protein] D-sedoheptulose D-glyceraldehyde L-alanyl-γ-D-glutamyl-L- of two intact strands a 5- L-homocysteine S-adenosylhomocysteine an L-glutaminyl- 6-phospho reactive oxygen species degradation reductase: 2-carboxy-4- dehydrogenase/ bifunctional 7-phosphate 3-phosphate 1939 guanosine methylenetetrahydrofolate Gln D-glucono- lysyl-D-alanyl-D-alanine methyluracil a relaxed DNA HMP-PP methylthiazol-5(2H thioredoxin pathway methenyltetrahydrofolate methylenetetrahydrofolate nucleosidase: [tRNA ] FC87_RS00910 thiamine dehydrogenase/ Gln in 23S rRNA a (6S)-5- FC87_RS03185 a tRNA 1,5-lactone phosphate )-ylidene]ethyl cyclohydrolase: dehydrogenase/ methenyltetrahydrofolate superoxide ADP RS04065 thiamine formyltetrahydrofolate 6-phosphogluconolactonase: synthase: phosphate an oxidized FC87_RS02305 methenyltetrahydrofolate cyclohydrolase: S-ribosyl-L- phosphate L-homocysteine FC87_RS00580 RS05190 FC87_RS01425 thioredoxin 10 cyclohydrolase: D-xylulose D-ribose 5- synthase: an N - FC87_RS02305 5-formyltetrahydrofolate homocysteine L-cystathionine FC87_RS02305 D-gluconate 5-phosphate phosphate thiamineFC87_RS01425 formyltetrahydrofolate cyclo-ligase: N-succinyl- adenine 1518 / adenosine a double thiamine Glu 6-phosphate hydrogen quinoxaline-2- [EntB aryl- an aromatic phosphate FC87_RS02375 coenzyme A 1519 L,L-2,6- 2',3'-cyclic 3'-AMP thioredoxin- serine peroxide acyl-carrier protein carrier protein] adenine in 16S rRNA a protein biotin ATP stranded DNA dITP IMP phosphate ribose 5- carboxyl adenylate 16S rRNA diaminopimelate monophosphate amino acid DNA gyrase RS02650 geranylgeranyl disulfide thiamine salvage III hydroxymethyltransferase: glyA bifunctional an L-glutamyl- ribulose- acyl carrier holo-ACP succinyl- multifunctional 2',3'- Xaa-Pro aromatic amino acid multifunctional 2',3'- a 5,10- phosphate (adenine(1518)-N(6)/ biotin--[acetyl- subunit A: non-canonical guanosine diphosphate biosynthesis reductase: methylenetetrahydrofolate [tRNA Glu ] phosphate 3- catalase: protein: synthase CitX: diaminopimelate cyclic-nucleotide 2'- dipeptidyl- aminotransferase: cyclic-nucleotide 2'- methenyltetrahydrofolate isomerase A: FC87_RS04155 purine NTP monophosphate RS02615 dehydrogenase/ a tRNA glu FC87_RS01535 FC87_RS04245 adenine(1519)-N(6))- desuccinylase: peptidase: phosphodiesterase/ CoA-carboxylase] cys FC87_RS00720 thiamine a 5,10- D-ribulose epimerase: FC87_RS00995 FC87_RS03360 phosphodiesterase/ FC87_RS05065 pyrophosphatase, reductase: (2E,6E)-farnesyl thiamine a 5-methyltetrahydrofolate methenyltetrahydrofolate CO dimethyltransferase: FC87_RS04690 FC87_RS05070 5'-nucleotidase/ ligase: DNA gyrase methylenetetrahydrofolate 2 5-phosphate FC87_RS02240 acyl carrier phosphopantetheinyl 5'-nucleotidase/ aromatic amino acid RdgB/HAM1 family: thiamine diphosphate diphosphate thiamine cyclohydrolase: ribose 5- FC87_RS05925 FC87_RS01630 subunit B: FC87_RS01245 H O hydroxyl radical protein: transferase: N 6 -dimethyladenine 1518 [+ 2 isozymes] 3'-nucleotidase: a peptide a dipeptide 3'-nucleotidase: biotinyl-5'- diphosphate farnesyltranstransferase: pyrophosphokinase: ribulose- phosphate O 2 aminotransferase: FC87_RS00110 FC87_RS02305 2 6 1519 L,L- FC87_RS02985 FC87_RS04160 guanosine FC87_RS02290 a reduced FC87_RS01580 FC87_RS01540 /N -dimethyladenine succinate FC87_RS02985 adenylate RS01385 FC87_RS02235 Aromatic Compound Biosynthesis phosphate 3- isomerase A: diaminopimelate FC87_RS03530 a negatively dIMP monophosphate thioredoxin thiamine a quinoxaline-2- a holo-[EntB aryl- in 16S rRNA an aromatic GGPP isoleucine-- epimerase: FC87_RS05720 3',5'-ADP 3'-AMP adenosine supercoiled DNA reductase: RS00525 diphosphate ile formate assimilation into 5,10- AMP carboxyl-[aryl- carrier protein] 2-oxo-acid 2,3-dihydroxybenzoate tRNA ligase: FC87_RS02240 carrier protein] FC87_RS04120 4-hydroxyphenylpyruvate FC87_RS03165 methylenetetrahydrofolate biosynthesis an L-isoleucyl- D-xylulose GMP biosynthesis [tRNA Ile ] 5-phosphate Amine and Polyamine Ile formate RS05145 chorismate a tRNA formate-- Degradation tyr phosphoketolase: tetrahydrofolate RS06275 FC87_RS06135 D-ribulose 4-aminobutanoate cytidine 2',3'-cyclic 2251 1-cis- a 1-alkyl-sn a 1-acyl-sn aromatic amino acid ligase: a 2,3,4-saturated a 2,3,4-saturated 2- a nucleoside guanosine dCDP Carbohydrate Biosynthesis 5-phosphate degradation III a ribonucleic acid monophosphate vaccenoylglycerol- -glycerol 3- 3'-GMP -glycerol 3- DNA with lesion methylglyoxal isochorismate aminotransferase: FC87_RS02030 hypoxanthine PRPP triphosphate in 23S rRNA D-glyceraldehyde 10 fatty acyl-[acp] lysophosphatidate multifunctional 2',3'- ribonucleoside- FC87_RS03530 leucine-- an N - 1-acyl-sn-glycerol- DNA-directed 23S rRNA 3-phosphate1-acyl-sn-glycerol- phosphate1-acyl-sn-glycerol- multifunctional 2',3'- phosphate1-acyl-sn-glycerol- excinuclease glyoxalase/ leu 3-phosphate acetyl phosphate 4-aminobutanoate xanthine cyclic-nucleotide 2'- diphosphate RS05440 UDP-N-acetyl-D- isochorismatase: tRNA ligase: formyltetrahydrofolate 3-phosphate RNA polymerase (guanosine(2251) 3-phosphate 3-phosphate cyclic-nucleotide 2'- 3-phosphate ABC subunit B: bleomycin aromatic amino acid 4-aminobutyrate phosphoribosyltransferase: phosphodiesterase/ reductase glucosamine biosynthesis I UDP-α-D-glucose FC87_RS05110 FC87_RS03580 glyceraldehyde- bifunctional acyltransferase: subunit alpha: -2'-O)- acyltransferase: acyltransferase: phosphodiesterase/ acyltransferase: FC87_RS00715 resistance/ aminotransferase: an L-leucyl- phosphate aminotransferase: FC87_RS05010 5'-nucleotidase/ subunit alpha: biosynthesis I (2S,3S)-2,3- FC87_RS05065 [tRNA Leu ] 3-phosphate methylenetetrahydrofolate FC87_RS03650 FC87_RS04855 methyltransferase 1-cis-vaccenoyl-FC87_RS03650 a 2-acyl-1-alkyl-FC87_RS03650 5'-nucleotidase/ a 1,2-diacyl-FC87_RS03650 excinuclease dioxygenase RS06100 D-glucopyranose acetyltransferase: FC87_RS05735 hypoxanthine a 2,3,4-saturated 3'-nucleotidase: FC87_RS00905 dihydroxy-2,3- 4-hydroxyphenylpyruvate a tRNA Leu dehydrogenase: dehydrogenase/ succinate RlmB: 2-palmitoleoyl 3'-nucleotidase: sn-glycerol ABC subunit C: family protein: β Cell Structure Biosynthesis 6-phosphate D-glucopyranose FC87_RS00635 1,2-diacyl-sn [+ 4 isozymes] FC87_RS02985 sn-glycerol peptidoglycan biosynthesis V ( -lactam resistance) glucose-6- dihydrobenzoate FC87_RS00675 methenyltetrahydrofolate phosphoribosyltransferase: acyl-carrier protein FC87_RS00965 FC87_RS02985 FC87_RS03350 FC87_RS03785 ribonucleoside- 6-phosphate semialdehyde -glycerol 3- a ribonucleic acid 2-O- phosphatidate 3-phosphate 3-phosphate FC87_RS05785 3'-cmp DNA without diphosphate phosphate phosphoglucomutase: acetyl-CoA cyclohydrolase: 2251 (R)-lactate RS04885 UDP-N-acetyl-α-D-glucosamine formaldehyde oxidation I phosphate methylguanosine isomerase: pgi FC87_RS01460 13-DPG FC87_RS02305 IMP guanosine lesion reductase: α Fatty Acid and in 23S rRNA UDP-N-acetylglucosamine F6P -D-glucopyranose acetaldehyde FC87_RS00910 2,3- valine-- a 5,10- Lipid Degradation RS06850 1-carboxyvinyltransferase: 1-phosphate val phosphoglycerate dehydrogenase D-ribulose 5-phosphate CDP glutamine- dihydroxybenzoate tRNA ligase: methenyltetrahydrofolate succinate FC87_RS05865 UTP--glucose- kinase: (acetylating): glycerol fructose-6- FC87_RS00265 an L-valyl- FC87_RS00670 FC87_RS05250 bifunctional UDP-N-acetylglucosamine 1-phosphate degradation I RS00790 phosphate [tRNA Val ] methylenetetrahydrofolate 3-hexulose-6- a single a [DNA]-3'- a 5'-phospho- 1-cis- a guanine 37 a cis-delta19- a cis-delta21-39- an L-1- UDP uridylyltransferase: 3-phospho- + a ribonucleoside a 3-oxoglutaryl- 1-carboxyvinyltransferase: Val NAD roseoflavin vaccenoylglycerol- phosphatidyl- transaminase a tRNA acetaldehyde dehydrogenase/ phosphate synthase: stranded DNA hydroxyl [DNA] ATP met in tRNA 37-methoxy-38- oxo-40-methyl- FC87_RS00340 FC87_RS00730 D-glycerate glycerol 5'-monophosphate [acp] methyl ester ribonucleoside- (isomerizing): methenyltetrahydrofolate FC87_RS04345 exodeoxyribonuclease DNA 5'-phosphate 3-phosphate1-acyl-sn-glycerol- tRNA (guanine(37) methyl-C57:1-[acp] C59:1-[acp]cyclopropane- sn-glycerol RS01220 alcohol glycerol kinase: bifunctional aromatic amino acid cyclopropane- beta-ketoacyl- diphosphate UDP-N-acetyl-α-D-glucosamine-enolpyruvate FC87_RS00590 UDP-α-D-glucose cyclohydrolase: VII small subunit: ligase bifunctional riboflavin -N(1))- lipid kinase: dehydrogenase: FC87_RS05560 metallophosphatase/ aminotransferase: 3-phosphate fatty-acyl- fatty-acyl- reductase FC87_RS02305 FC87_RS02295 (NAD(+)) kinase/FMN methyltransferase: ACP reductase: FC87_RS04745 D-glucosamine D-gluconate 6-phosphate hexulose 6-phosphate 5'-nucleotidase: FC87_RS05065 acyltransferase: phospholipid phospholipid subunit alpha: UDP-N- FC87_RS05250 glycerol kinase: LigA: ligA adenylyltransferase: FC87_RS02160 FC87_RS01590 RS02070 6-phosphate 2-phospho- a 5,10- exodeoxyribonuclease FC87_RS06255 1,2-dicis- FC87_RS03650 an N 1 - synthase: a (3R)-3- synthase: 1-(3-sn- FC87_RS00905 acetylenolpyruvoylglucosamine UDP-α-D-galactofuranose ala alanine-- FC87_RS02115 FC87_RS03750 aromatic amino acid D-glycerate ethanol methylenetetrahydrofolate sn-glycerol VII large subunit: roseoflavin adenine [+ 2 isozymes] vaccenoyl- methylguanine 37 FC87_RS01840 hydroxyglutaryl- FC87_RS01840 phosphatidyl) reductase: FC87_RS00615 phosphoglucosamine tRNA ligase: NMN AMP [DNA] aminotransferase: ribonucleoside- biosynthesis phosphopyruvate 6-phospho-3- FC87_RS02300 dinucleotide phosphatidate in tRNA a cis-methoxy- [acp] methyl ester a cis-keto-C60- -sn-glycerol mutase: FC87_RS00595 FC87_RS00155 an L-alanyl- 6-phosphogluconolactonase: 3-phosphate a ribonucleoside FC87_RS03530 RS03110 hexuloisomerase: a single-stranded a ribonucleoside 4-(methylsulfanyl) C59-meroacyl-[acp] meroacyl-[acp] diphosphate α Ala hydratase: FC87_RS00580 3-phosphate Glu α D-glucosamine UDP- -D-glucose [tRNA ] FC87_RS04340 oligodeoxyribonucleotide 5'-monophosphate reductase: ala UDP-N-acetyl- -D-muramate Ala FC87_RS00660 -2-oxobutanoate 1-phosphate UDP-glucose 4-epimerase a tRNA FC87_RS00910 RS04045 GalE: FC87_RS01470 phosphoenol glutamate racemase: peptidoglycan biosynthesis I (meso-diaminopimelate containing) 6-phospho D-glucono-1,5-lactone dUDP UDP-N-acetylmuramate- bifunctional N- UDP-α-D-galactose pyruvate F6P DHAP FC87_RS00115 acetylglucosamine- glucose-6-phosphate + + -L-alanine ligase: UDP-N-acetyl- NADP + -dependent H RS00380 H UDP-galactopyranose pyruvate kinase: isomerase: pgi FC87_RS02535 α-D-glucosamine 1-phosphate PRPP biosynthesis I glucose-6-phosphate a reduced a (7Z,10Z,13Z,16Z (S)-1-pyrroline- a double- D-glt mutase: FC87_RS01315 asparagine-- FC87_RS03920 a CDP- sn-glycerol 1-myristoylglycerol a ribonucleoside 1-myristoylglycerol a 3-oxohexadecanoyl- a 3-oxohexanoyl- uridyltransferase/ asn ferredoxin [iron- NADP + H + ,19Z)-3-oxodocosa- α UDP-N-acetylglucosamine tRNA ligase: dehydrogenase: diacylglycerol 3-phosphate a myristoyl-[acp] 3'-phosphate 3-phosphate 2'-deoxyadenosine 5-carboxylate helix DNA XTP UDP-N-acetyl- -D-muramoyl-L-alanine glucosamine- D-ribose 5- UDP-Galf 3-phosphate [acp] [acp] L-glutamate DNA helicase RS02720 1-carboxyvinyltransferase: FC87_RS00575 pyruvate FC87_RS01185 CDP-diacylglycerol-- 1-acyl-sn-glycerol- sulfur] cluster ferredoxin- 7,10,13,16,19-pentaenoyl-[acp] multifunctional 2',3'- 1-acyl-sn-glycerol- 1-phosphate phosphate an L-asparaginyl- beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- gamma- PcrA: non-canonical FC87_RS05865 ribose-phosphate Asn glycerol-3-phosphate 3- 3-phosphate -NADP(+) cyclic-nucleotide 2'- 3-phosphate adenosine RS06315 UDP-N-acetylmuramoyl- acetyltransferase: [tRNA ] ACP reductase: ACP reductase: ACP reductase: semialdehyde FC87_RS04775 purine NTP Asn phosphatidyltransferase: acyltransferase: deaminase: L-alanine--D-glutamate UDP-N-acetylglucosamine pyrophosphokinase: tRNA D-glucopyranose 6-phosphate acyltransferase: reductase: phosphodiesterase/ FC87_RS01590 pyrophosphatase, FC87_RS05900 L-lactate pyruvate FC87_RS00215 FC87_RS01590 FC87_RS03650 FC87_RS01590 dehydrogenase: [+ 2 isozymes] ligase: FC87_RS03120 1-carboxyvinyltransferase: FC87_RS03220 1-(3-sn- FC87_RS03650 an FC87_RS06045oxidized a (3R,7Z,10Z,13Z,16Z 5'-nucleotidase/ 1-myristoyl-2- a (3R)-3- FC87_RS05330 a (3R)-3- an unwound RdgB/HAM1 family: N-acetyl-α-D- dehydrogenase: fermentation dimyristoyl FC87_RS04375 FC87_RS00340 ribose-phosphate phosphatidyl) acyl-carrier protein NADPH ferredoxin [iron- ,19Z)-3-hydroxydocosa- 3'-nucleotidase: palmitoleoyl hydroxyhexadecanoyl- hydroxyhexanoyl- double- FC87_RS00110 glucosamine FC87_RS00915 CMP phosphatidate D-ala lys UDP-N-acetyl-α-D-muramoyl- UDP-N-acetyl-α- (R)-lactate to (S)-acetoin 7,10,13,16,19-pentaenoyl-[acp] FC87_RS02985 phosphatidate [acp] 2'-deoxyinosine [acp] Glu stranded DNA RS01300 1-phosphate pyrophosphokinase: -sn-glycerol sulfur] cluster L-alanyl-D-glutamate XMP D-glucosamine- FC87_RS05895 pyruvate 3-phosphate a ribonucleoside RS01485 bifunctional N- aspartate-- (S)-lactate D-alanine--D-alanine enolpyruvate PRPP asp acetolactate Carbohydrate Degradation acetylglucosamine- tRNA ligase: ligase A: FC87_RS00315 UDP-N- synthase: FC87_RS03825 an L-aspartyl- acetylenolpyruvoylglucosamine 1-phosphate FC87_RS04060 D-galactose degradation I (Leloir pathway) uridine 2'3'-cyclic UDP-N-acetyl-α-D-muramoyl- [tRNA asp ] 1-(3-sn- a cytidine 1402 1-palmitoylglycerol 3'-UMP a (7Z)-3-oxo- (3R,5S)-3- a (5Z)-3- D-alanyl-D-alanine reductase: FC87_RS00615 uridyltransferase/ (S)-2-acetolactate 2'-deoxy-α-D-ribose 1- 1-palmitoylglycerol an alkylated DNA monophosphate a 3-oxotetracosanoyl- RS00655 γ tRNA asp phosphatidyl) a myristoyl-[acp] in 16S rRNA 3-phosphate hexadec-7- hydroxy-1- oxododec- ITP L-alanyl- -D-glutamyl-L-lysine glucosamine- phosphate degradation 3-phosphate multifunctional 2',3'- [acp] UDP-N-acetyl- β-D-galactose -sn-glycerol 1-acyl-sn-glycerol- DNA-3- 16S rRNA 1-acyl-sn-glycerol- multifunctional 2',3'- enoyl-[acp] pyrroline-5- 5-enoyl-[acp] ala 1-phosphate cyclic-nucleotide 2'- beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- non-canonical RS06820 α-D-muramate 2-deoxy-α-D- 3-phosphate phosphatidylglycerophosphatase: methyladenine (cytosine(1402)-N(4) 3-phosphate cyclic-nucleotide 2'- carboxylatepyrroline-5- UDP-N-acetylmuramoyl- Glu acetyltransferase: 3-phosphate ACP reductase: ACP reductase: ACP reductase: purine NTP galactose ribose 1-phosphate FC87_RS04395 glycosylase: )-methyltransferase: phosphodiesterase/ acyltransferase: phosphodiesterase/ carboxylate tripeptide--D-alanyl- FC87_RS05900 acyltransferase: mutarotase: FC87_RS05485 FC87_RS03100 5'-nucleotidase/ FC87_RS01590 5'-nucleotidase/ FC87_RS01590 FC87_RS01590 pyrophosphatase, D- alanine ligase: glutamate UDP-N- diacetyl phosphatidylglycerophosphatase FC87_RS03650 a DNA containing an N 4 - FC87_RS03650 a (3R)-3- a (3R,7Z)-3- reductase: a (3R,5Z)-3- UDP-N-acetyl- tyrosine-- FC87_RS06475 phosphopentomutase: 1-palmitoyl- 3'-nucleotidase: 1-palmitoyl-2- RdgB/HAM1 family: acetylmuramate-- tyr an L-1- an alkylated 1402 3'-nucleotidase: FC87_RS01440 RS01270 FC87_RS05840 racemase: α-D-glucosamine tRNA ligase: FC87_RS01770 A: FC87_RS03630 acyl-carrier protein 2-myristoyl an apurinic/ methylcytidine palmitoleoyl hydroxytetracosanoyl- hydroxy-hexadec- trans-4-hydroxy- hydroxydodec- FC87_RS00110 L-alanine ligase: acetoin α phosphatidyl- nucleobase FC87_RS02985 FC87_RS02985 FC87_RS00115 FC87_RS05545 -D-galactose 2-deoxy-D-ribose phosphatidate apyrimidinic site in 16S rRNA phosphatidate [acp] 7-enoyl-[acp] L-proline 5-enoyl-[acp] UDP-N-acetyl-α-D-muramoyl-L-alanyl- FC87_RS02535 an L-tyrosyl- reductase: sn-glycerol 3'-UMP uridine IMP RS05610 γ [tRNA Tyr ] 5-phosphate -D-glutamyl-L-lysyl-D-alanyl-D-alanine D-glt UDP-N-acetyl-α-D- FC87_RS03780 a tRNA Tyr muramoyl-L-alanine (S)-acetoin α-D-galactose α a nascent peptidoglycan a peptidoglycan 966 a (9Z)-3- RS01400 α UDP-N- UDP- -D-glucose 1-[18-hydroxyoleyl]- a guanine 1-palmitoylglycerol 3'-cmp UDP-N-acetyl- -D-muramoyl-L- 1-phosphate γ γ 1-palmitoylglycerol H O diphosphate a 3-oxotetradecanoyl- a 3-oxodecanoyl- a cis-delta15-3- with (L-alanyl- -D- with (L-alanyl- -D- a palmitoyl-[acp] 2 in 16S rRNA oxooctacos- D-ribose RS05565 D-ribose γ acetylmuramoyl- D-glyceraldehyde 3-phosphate 2-lyso-phosphatidate 3-phosphate [acp] [acp] dIDP alanyl- -D-glutamyl-L-lysyl-D-alanine acetaldehyde glutamyl-meso-2,6- glutamyl-meso-2,6- 1-acyl-sn-glycerol- 16S rRNA multifunctional 2',3'- oxo-C34:1-[acp] 9-enoyl-[acp] L-alanine--D- tryptophan-- 3-phosphate 1-acyl-sn-glycerol- manganese- 1-acyl-sn-glycerol- Trp beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- a tRNA diaminopimeloyl-D- diaminopimeloyl-D- dependent inorganic 3-phosphate (guanine(966)-N(2) 3-phosphate cyclic-nucleotide 2'- glutamate ligase: tRNA ligase: Macromolecule Modification acetaldehyde L,D- 3-phosphate ACP reductase: ACP reductase: ACP reductase: ACP reductase: alanine) tetrapeptide alanine) tetrapeptide pyrophosphatase: acyltransferase: )-methyltransferase acyltransferase: phosphodiesterase/ UDP kinase: FC87_RS03120 FC87_RS05970 an L-tryptophanyl- dehydrogenase transpeptidase: acyltransferase: D-ribose RS05570 D-ribose undecaprenyl-diphospho-N-acetylmuramoyl- a nascent peptidoglycan FC87_RS03650 RsmD: FC87_RS03650 FC87_RS01590 5'-nucleotidase/ FC87_RS01590 FC87_RS01590 FC87_RS01590 FC87_RS03865 RS04800 Trp FC87_RS04475 FC87_RS03650 FC87_RS01905 1-[18-hydroxyoeoyl]-2- 1-palmitoyl-2- a (3R)-3- a (3R)-3- a cis-delta15-3- a cis-delta9-3- L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine [tRNA ] tRNA processing (acetylating): with L,D cross links dipalmitoyl FC87_RS03275 3'-nucleotidase: UDP-N-acetyl- Nucleoside and Nucleotide Biosynthesis D-ala acyl-carrier protein phosphate H + [18-hydroxy-lioleoyl]-sn an N 2 - cis-vaccenoyl hydroxytetradecanoyl- hydroxydecanoyl- hydroxyC34:1- hydroxyC28:1- trp FC87_RS05250 (meso-diaminopimelate FC87_RS02985 undecaprenyldiphospho- meso-diaminopimelate α-D-muramoyl-L- phosphatidate 966 dITP -glycerol 3-phosphate methylguanine phosphatidate [acp] [acp] [acp] [acp] 2+ 2+ muramoylpentapeptide beta-N- a polycistronic acetyl-CoA containing) cytidine Co RS05165 Co alanyl-D-glutamate superpathway of pyrimidine in 16S rRNA acetylglucosaminyltransferase: superpathway of guanosine CMP tRNA precursor deoxyribonucleotides de novo biosynthesis superpathway of adenosine superpathway of pyrimidine FC87_RS03125 UDP-N- nucleotides de novo biosynthesis I nucleotides de novo biosynthesis I nucleobases salvage phosphorylation RS05980 threonine-- 1-cis- a 2'- 2-(2-carboxy-4- a 3- a (3R,5Z)-3- ditrans,octacis-undecaprenyldiphospho- acetylmuramoyl- a cis- 1-palmitoylglycerol a cis-delta21-3- a [protein]-L- Co 2+ RS04835 Co 2+ CMP thr 1-myristoylglycerol deoxyribonucleoside [DNA] methylthiazol-5- HMP-PP NaMN a 3-oxooctadecanoyl- N-acetyl-(N-acetylglucosaminyl)muramoyl- L-alanyl-D- gln hydrogencarbonate uracil tRNA ligase: a palmitoleoyl-[acp] vaccenoylglycerol- 3-phosphate oxodocosanoyl- hydroxy-tetradec- methionine IDP cytidylate kinase: UDP-glucose 4- 3-phosphate vaccenoyl-[acp] yl)ethyl phosphate [acp] oxo-C40:1-[acp] γ asp IMP IMP uracil FC87_RS02500 an L-threonyl- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol-3-phosphate 5'-triphosphate DNA polymerase thiamine bifunctional 1-acyl-sn-glycerol- [acp] 5-enoyl-[acp] methionine L-alanyl- -D-glutamyl-L-lysyl-D-alanine glutamate--2, 6- FC87_RS03975 a tRNA precursor a tRNA precursor epimerase GalE: beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- carbamoyl- phosphoribosyltransferase: [tRNA Thr ] 3-phosphate 3-phosphate III subunit beta: phosphate metallophosphatase/ 3-phosphate sulfoxide diaminopimelate CDP with a 5' with a 5' FC87_RS01470 ACP reductase: ACP reductase: ACP reductase: ACP reductase: UDP kinase: D-ala phosphate synthase: IMP FC87_RS00390 a tRNA Thr α-D-glucopyranose acyltransferase: acyltransferase: FC87_RS04175 synthase: 5'-nucleotidase: acyltransferase: reductase A: ligase: adenylosuccinate extension and extension and a UDP-α-D-galactose FC87_RS01590 FC87_RS01590 FC87_RS01590 FC87_RS01590 FC87_RS03865 RS01330 FC87_RS02005 dehydrogenase: UDP kinase: 1-phosphate FC87_RS01425 FC87_RS06255 FC87_RS03650 FC87_RS01915 RS05240 ditrans,octacis-undecaprenyldiphospho-N FC87_RS02630 synthase: bifunctional pyr operon a long 3' trailer short 3' extension FC87_RS036501-myristoyl-2- FC87_RS036501,2-dicis- [+ 7 isozymes] 1-palmitoyl- a (3R)-3- a (3R)-3- a (5Z)-3-oxo- a cis-delta21-3- a protein-L- D-alanine--D- [+ 3 isozymes] FC87_RS01245 FC87_RS03865 thiamine [+ 2 isozymes] -acetyl-(N-acetylglucosaminyl)muramoyl-L- FC87_RS01545 transcriptional regulator/uracil ribonuclease acyl-carrier protein palmitoleoyl acyl-carrier protein vaccenoyl- [DNA] β 2-myristoyl hydroxyoctadecanoyl- hydroxydocosanoyl- tetradec-5- hydroxyC40:1- methionine- alanine ligase A: phosphoglucomutase: phosphate -D- ITP γ UDP-N-acetyl-α-D- phosphoribosyltransferase: CTP P protein phosphatidate phosphatidate phosphatidate [acp] [acp] enoyl-[acp] [acp] (S)-S-oxide alanyl- -D-isoglutaminyl-L-lysyl-D-alanine FC87_RS00315 ribosylnicotinate muramoyl-L-alanyl- asp carbamoyl phosphate adenylo-succinate XMP FC87_RS02015 component: FC87_RS01460 ser serine-- glucose and glucose-1-phosphate degradation γ-D-glutamyl-meso- UMP a tRNA FC87_RS04190 D-glucopyranose an anion RS04055 an anion predicted D-alanyl-D-alanine adenylosuccinate tRNA ligase: 2,6-diaminopimelate aspartate precursor with a tRNA precursor 6-phosphate ABC UMP kinase: FC87_RS05095 an L-seryl- α-D-glucopyranose 1-cis- a 3- Peptide Peptide ditrans,octacis-undecaprenyldiphospho- carbamoyltransferase: lyase: with a short (R)-mevalonate a 3- transporter FC87_RS03675 [tRNA ser ] a 5' extension 1-phosphate a cis- 1-palmitoylglycerol 3'-dephospho- a 3-oxohexacosanoyl- a 3-oxooctanoyl- a cis-delta17-3- N-acetyl-(N-acetylglucosaminyl) FC87_RS00490 FC87_RS01550 a palmitoleoyl-[acp] vaccenoylglycerol- oxododecanoyl- oxodocosanoyl- pro asp of a peptide UDP-N- pyrimidine a tRNA ser 3' extension vaccenoyl-[acp] 3-phosphate 5-phosphate ATP FMN ATP [acp] [acp] oxo-C36:1-[acp] muramoyl-L-alanyl-γ-D-isoglutaminyl- cytidylate kinase: 3-phosphate 1-acyl-sn-glycerol- CoA [acp] [acp] an anion RS05135 an anion acetylmuramoyl- nucleobases salvage II ribonuclease 1-acyl-sn-glycerol- dephospho- beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- pyrroline-5- aspartate N-(β-D-asparatyl)-L-lysyl-D-alanine FC87_RS03975 sugar- phosphomevalonate bifunctional riboflavin lactate RS04300 lactate tripeptide-- N-carbamoyl-L-aspartate AMP GMP P protein 3-phosphate 3-phosphate CoA kinase: carboxylate cytosine phosphoglucomutase: phosphatase: kinase: FC87_RS02100 kinase/FMN ACP reductase: ACP reductase: ACP reductase: ACP reductase: ACP reductase: racemase: D-alanyl-D- UDP component: acyltransferase: acyltransferase: FC87_RS02520 reductase: cytosine deaminase: FC87_RS01460 FC87_RS05890 adenylyltransferase: FC87_RS01590 FC87_RS01590 FC87_RS01590 FC87_RS01590 FC87_RS01590 FC87_RS02620 alanine ligase: dihydroorotase: FC87_RS04190 FC87_RS036501-cis-vaccenoyl- FC87_RS036501-palmitoyl-2- + a (3R)-3- a (3R)-3- a (3R)-3- a (3R)-3- a cis-delta17-3- FC87_RS01440 glycine glycine guanylate kinase: UDP kinase: FC87_RS01555 (R)-mevalonate ADP coenzyme A H RS05495 adenylate kinase: proline-- glucokinase: FC87_RS03750 hydroxyhexacosanoyl- hydroxydodecanoyl- hydroxydocosanoyl- hydroxyoctanoyl- hydroxyC36:1- (S)-1-pyrroline- D-aspartate ditrans,octacis-undecaprenyldiphospho- FC87_RS05840 FC87_RS00485 FC87_RS03865 uracil pro acyl-carrier protein 2-palmitoleoyl acyl-carrier protein cis-vaccenoyl diphosphate FAD betaine betaine ammonia RS05740 ammonia FC87_RS04880 FC87_RS02275 tRNA ligase: FC87_RS02360 D-glucopyranose 5-carboxylate N-acetyl-(N-acetylglucosaminyl) an uncharged phosphatidate phosphatidate [acp] [acp] [acp] [acp] [acp] α UTP uracil FC87_RS03705 an L-prolyl- D-glucopyranose muramoyl-L-alanyl-γ-D-isoglutaminyl- UDP-N-acetyl- -D- (S)-dihydroorotate tRNA phosphoribosyltransferase: Pro 6-phosphate N-(β-D-asparaginyl)-L-lysyl-D-alanine muramoyl-L-alanyl- ADP GDP CTP synthase: [tRNA ] glycine glycine arg arg FC87_RS00390 Pro 1-stearoyl- 37 a (9Z)-3-oxo- RS05450 γ-D-glutamyl-meso- dihydroorotate FC87_RS05870 a tRNA 1-palmitoylglycerol an acyl-[acyl- S-methyl-L- ADP-D-ribose guanine a 3-oxoicosanoyl- a cis-delta11-3- long chain betaine betaine a palmitoleoyl-[acp] sn-glycerol L-homocysteine Phe an acetoacetyl-[acp] octadec-9- ala RS05260 di-trans,octa-cis- oxidase: bifunctional pyr operon acyl-carrier protein in tRNA polyphosphate 2,6-diaminopimeloyl- CTP 3-phosphate carrier protein] methionine ADP-ribose [acp] oxo-C30:1-[acp] undecaprenyl phosphate FC87_RS00495 D-glucono-1,5-lactone 1-acyl-sn-glycerol- 1-acyl-sn-glycerol-3-phosphate homocysteine S- tRNA (guanine(37) enoyl-[acp] ornithine ornithine D-alanyl-D-alanine UDP kinase: transcriptional regulator/uracil pyrophosphatase: ACP S- beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- polyphosphate alanine chloride RS01255 chloride F0F1 ATP ribonucleoside- ribonucleoside- lipoprotein posttranslational xylose degradation I 3-phosphate 3-phosphate methyltransferase: -N(1))- glycine glycine a peptidoglycan dimer (tetrapeptide) FC87_RS03865 phosphoribosyltransferase: FC87_RS03175 malonyltransferase: ACP reductase: ACP reductase: ACP reductase: ACP reductase: kinase 1: racemase: RS05455 orotate PRPP synthase diphosphate diphosphate modification FC87_RS04660 methyltransferase: betaine betaine FC87_RS02015 phenylalanine- acyltransferase: acyltransferase: FC87_RS01585 FC87_RS01590 FC87_RS01590 FC87_RS01590 FC87_RS01590 FC87_RS04505 FC87_RS05830 subunit epsilon: reductase: reductase: D-ribofuranose 1 FC87_RS02160 -tRNA ligase a [prolipoprotein]- D-xylopyranose FC87_RS036501-palmitoyl-2- FC87_RS03650a 1-stearoyl 2- met AMP an N - a (3R)-3- a (3R)-3- a (3R,9Z)-3- a cis-delta11-3- long chain 2+ 2+ orotate FC87_RS00350 FC87_RS00910 FC87_RS00910 UMP 37 Co Co undecaprenyldiphospho- guanine and subunit beta: L-cysteine D-gluconate acyl-carrier protein palmitoleoyl acyl-carrier protein acyl-sn-glycerol 5-phosphate a malonyl-[acp] methylguanine hydroxybutanoyl- hydroxyicosanoyl- hydroxy-octadec- hydroxyC30:1- polyphosphate D-ala 2+ RS06025 2+ phosphoribosyltransferase: GTP Mg Mg a peptidoglycan tetramer with L,D [+ 7 isozymes] ribonucleoside- ribonucleoside- in tRNA Phe [acp] [acp] 9-enoyl-[acp] [acp] glycine glycine N-acetylmuramoyl-L- FC87_RS01515 guanosine salvage FC87_RS02395 prolipoprotein phosphatidate 3-phosphate RS05445 γ diphosphate diphosphate betaine betaine cross-links (L-lys-D-Asn-L-Lys) alanyl- -D-glutamyl-meso phenylalanine- diacylglyceryl D-xylulose reductase reductase -2,6-diaminopimeloyl- -tRNA ligase transferase: orotidine 5'-phosphate 1-stearoyl- 1915 2-dehydro- a (9Z)-3- a [protein]- D-alanyl-D-alanine ATP subunit alpha: subunit alpha: guanosine phe xylulokinase: a pseudouridine a single a RNA-DNA hybrid a 3-oxopimeloyl- a cis-delta19-3- a D-hexose subunit alpha: FC87_RS00740 an oleoyl-[acp] sn-glycerol phosphoenol 3-deoxy-D- oxohexadec- RS05140 undecaprenyldiphospho- FC87_RS00905 FC87_RS00905 FC87_RS05300 in 23S rRNA stranded DNA ATP H O dGDP [acp] methyl ester oxo-C38:1-[acp] L-histidine a peptidoglycan with (L-alanyl-γ-D-glutamyl- FC87_RS02400 a [prolipoprotein]- 23S rRNA 2 RNase HI: pyruvate gluconate orotidine-5'- an L-phenylalanyl- 1-acyl-sn-glycerol-3-phosphate 9-enoyl-[acp] glucokinase: RS03135 muramoylpentapeptide beta-N- Phe (S-diacylglyceryl) D-xylulose deoxyribonuclease 2-dehydro-3- beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- histidine kinase: L-lysyl-D-alanyl-D-alanine) pentapeptide phosphate [tRNA ] 3-phosphate (pseudouridine(1915)- ATPase: FC87_RS05505 pyruvate kinase: acetylglucosaminyltransferase: Phe -L-cysteine 5-phosphate IV: FC87_RS03840 deoxygluconokinase: ACP reductase: ACP reductase: ACP reductase: FC87_RS01825 FC87_RS02360 decarboxylase: guanine a tRNA acyltransferase: N(3))-methyltransferase FC87_RS04405 ribonuclease HII: FC87_RS03920 FC87_RS03125 dADP dGDP FC87_RS05595 FC87_RS01590 FC87_RS01590 FC87_RS01590 FC87_RS01510 Carboxylate Degradation 3 RlmH: FC87_RS04075 FC87_RS04030 a [protein]- lipid II (meso FC87_RS036501-stearoyl-2- an N - + a (3R)-3- a (3R,9Z)-3- a cis-delta19-3- D-hexose 6- signal peptidase a 5'-phosphooligonucleotide H phosphate ADP a nucleoside 5'- dGTP pyruvate N-phospho- RS00135 a peptidoglycan with (L-alanyl-γ-D-glutamyl- diaminopimelate xanthine acyl-carrier protein oleoyl-sn-glycerol methylpseudouridine 1915 DNA KDGP hydroxypimeloyl- hydroxyhexadec- hydroxyC38:1- phosphate UMP II: FC87_RS02025 monophosphate L-histidine L-lysyl-D-alanyl-D-alanine) pentapeptide containing) UDP kinase: UDP kinase: phosphoribosyltransferase: pyruvate fermentation 3-phosphate in 23S rRNA [acp] methyl ester 9-enoyl-[acp] [acp] RS05435 UMP kinase: FC87_RS03865 FC87_RS03865 FC87_RS05010 methionine-- an (S-diacyl- citrate degradation L-malate met a lipoprotein to acetate IV FC87_RS03675 hypoxanthine tRNA ligase: sn-glyceryl) degradation II signal peptide an acetyl-holo a (7Z)-3- cytidylate kinase: phosphoribosyltransferase: FC87_RS05940 an L-methionyl- -L-cysteinyl- pyruvate a ring-opened 7- an N-modified (R)-mevalonate a cis-delta13-3- a nucleoside dATP dGTP citrate phosphoenol riboflavin a uridine in tRNA oxohexacos- (S)-malate FC87_RS03975 [elongator [citrate lyase acyl- (S)-malate methylguanine in DNA adenine PRPP diphosphate GTP H O dADP diphosphate FC87_RS05785 [apolipoprotein] aminoacyl-[tRNA] 2 oxo-C32:1-[acp] RS03290 elongator tRNA Met ] carrier protein] citrate lyase: malate DNA- aminoacyl-tRNA pyruvate bifunctional riboflavin tRNA 7-enoyl-[acp] fumarate UDP Met adenine diphosphomevalonate GTPase HflX: beta-ketoacyl- beta-ketoacyl- tRNA FC87_RS04230 dehydrogenase: formamidopyrimidine hydrolase: pyruvate kinase: kinase/FMN dihydrouridine UDP kinase: hydratase: GMP xanthine and phosphoribosyltransferase: decarboxylase: FC87_RS05215 ACP reductase: ACP reductase: RS02600 L-lysine biosynthesis II Amino Acid Biosynthesis a citryl-holo[+ 2 isozymes] FC87_RS06165 glycosylase: FC87_RS05815 FC87_RS03920 adenylyltransferase: synthase DusB: FC87_RS03865 FC87_RS01560 superpathway of L-serine L-homoserine a peptide FC87_RS03385 FC87_RS02095 FC87_RS01590 FC87_RS01590 ribonucleoside- UDP kinase: xanthosine salvage an N-acyl-(S- [citrate lyase acyl- pyruvate FC87_RS02525 an N-modified an uncharged [+ 3 isozymes] FC87_RS03750 FC87_RS05770 and glycine biosynthesis I biosynthesis 2,6-diamino-4- + dATP pyruvate a (3R,7Z)-3- a cis-delta13-3- a nucleoside diphosphate FC87_RS03865 diacyl-sn-glyceryl) acetyl-CoA formate carrier protein] an apurinic site AMP amino acid tRNA IPP phosphate GDP H a 5,6-dihydrouridine fumarate hydroxy-5-(N-methyl) FMN hydroxyhexacos- hydroxyC32:1- triphosphate asp 3-phospho- reductase: lysine-- -L-cysteinyl- citrate lyase: within DNA in tRNA RS00755 xanthosine a tRNA Lys phosphate formamidopyrimidine 7-enoyl-[acp] [acp] D-glycerate asp FC87_RS00910 tRNA ligase: [lipoprotein] FC87_RS04230 aspartate kinase: 3-phosphoglycerate superpathway of L- gln UTP acetyltransferase: citrate RS03460 citrate ribonucleoside- FC87_RS05765 an L-lysyl- [+ 2 isozymes] FC87_RS06270 dehydrogenase: aspartate kinase: asparagine biosynthesis guanine and FC87_RS00635 superpathway of pyrimidine deoxyribonucleoside salvage Lys decaprenyl-diphospho-N- UDP-N-acetyl- a 7,8-dihydro-8- an apo-[LYS2 L- an (S)-2- 1-oleyl-2-lyso- a (7Z)-3- a supercoiled D-sorbitol L-aspartyl- FC87_RS05600 FC87_RS06270 diphosphate [tRNA ] D-gluconate roseoflavin 1-myristoylglycerol CTP synthase: guanosine salvage II xanthine oxaloacetate acetylmuramoyl-pentapeptide α-D-glucosamine oxoguanine in DNA 2-aminoadipyl- coenzyme A halocarboxylate β-alanine phosphatidate oxotetradec- repressor LexA duplex DNA 6-phosphate 4-phosphate 3-phosphooxypyruvate L-aspartyl- asp reductase lys acetyl phosphate degradation 3-phosphate 2'-deoxycytidine 6 undecaprenyldiphospho- DNA- carrier-protein] haloacid bifunctional riboflavin 1-acyl-sn-glycerol- 7-enoyl-[acp] ATP-dependent 4-phosphate subunit alpha: FC87_RS05870 N -L- holo-ACP 1-acyl-sn-glycerol- sugar- RS06500 xanthine 37 kinase/FMN 4-aminobutyrate beta-ketoacyl- RS03835 aspartate- threonylcarbamoyladenosine muramoylpentapeptide beta-N- formamidopyrimidine synthase CitX: dehalogenase: 3-phosphate 3-phosphate repressor LexA: DNA helicase: phosphatase: FC87_RS00905 CTP guanosine phosphoribosyltransferase: acetate kinase: D-gluconate aminotransferase: ACP reductase: semialdehyde aspartate- -modified tRNA biosynthesis acetylglucosaminyltransferase: glycosylase: FC87_RS00520 adenylyltransferase: acyltransferase: FC87_RS05205 asparagine asparagine gluconate kinase: a holo-[LYS2 L- FC87_RS04245 acyltransferase: FC87_RS03635 FC87_RS05890 FC87_RS05010 FC87_RS02975 FC87_RS03125 FC87_RS03750 FC87_RS05735 FC87_RS01590 [+ 4 isozymes] dehydrogenase: semialdehyde FC87_RS02525 3',5'-ADP [+ 4 isozymes] FC87_RS03650 FC87_RS03650 synthase synthase dUDP histidine-- FC87_RS04640 decaprenyl-pyrophosphoryl- an apurinic site 7,8-dihydro- 2-aminoadipyl- an (R)-2- roseoflavin dimyristoyl dioleoyl a (3R,7Z)-3- a single D-sorbitol FC87_RS01120 3-phospho- dehydrogenase: 2'-deoxyuridine dCMP his ATP thr D-gluconate a halide anion 3-oxopropanoate cleaved (glutamine- (glutamine- tRNA ligase: acetate UDP (N-acetylglucosamine)-N- within DNA 8-oxoguanine carrier-protein] hydroxyacid phosphatidate hydroxytetradec- stranded DNA L-serine FC87_RS01120 UDP kinase: XMP 6-phosphate 5'-phosphate phosphatidate repressor LexA L-aspartate- hydrolyzing): hydrolyzing): CDP cytidylate kinase: guanine FC87_RS01250 threonylcarbamoyl- acetylmuramyl-(pentapeptide) 7-enoyl-[acp] RS05305 FC87_RS03865 thymidine kinase: an L-histidyl- RS04370 semialdehyde L-aspartate- FC87_RS05365 FC87_RS05365 FC87_RS03975 His AMP synthase: ribonucleoside- FC87_RS00415 [tRNA ] semialdehyde dUTP xanthine His FC87_RS00400 4-hydroxy- a tRNA an N-formyl-L- 967 a (5Z)-3- diphosphate dCDP L-threonylcarbamoyladenylate phosphatidylglycerophosphate a cytosine long chain an L-cysteinyl- uridine tetrahydrodipicolinate dUTP thymidine phosphoribosyltransferase: Nucleoside and Nucleotide Degradation methionylaminoacyl- citrate (R)-pantothenate (R)-mevalonate acetyl-CoA reductase: dUMP 4'-phosphopantetheine ATP in 16S rRNA Cys oxotetracos- asn asn UDP kinase: FC87_RS05010 (1-octadecenoyl(9Z), 2-palmitoyl) polyphosphate [tRNA ] acetyl-CoA synthase: ser diphosphatase: FC87_RS00910 phosphatidylglycerophosphatase tRNA peptide 16S rRNA citrate lyase pantothenate aminoacyl-tRNA 5-enoyl-[acp] mevalonate uridine kinase: FC87_RS00990 thymidine kinase: FC87_RS03865 hypoxanthine pantetheine-phosphate subunit alpha: beta-ketoacyl- carboxylase: FC87_RS02390 FC87_RS01110 ribonucleoside- thymidylate adenosine nucleotides A: FC87_RS03630 deformylase: (cytosine(967)-C(5)) exopolyphosphatase: kinase: hydrolase: kinase: RS03955 (2S,4S)-4- FC87_RS00415 phosphoribosyltransferase: adenylyltransferase: FC87_RS04240 ACP reductase: FC87_RS01935 synthase: dCTP pyrimidine glycine-- an N 6 -L- degradation II S-methyl-5'-thioadenosine FC87_RS03245 -methyltransferase: FC87_RS05965 FC87_RS05200 FC87_RS05815 FC87_RS02090 RS04645 hydroxy-2,3,4,5- serine L-homoserine dUMP diphosphate phosphatidylglycerophosphatase: FC87_RS01590 UMP FC87_RS04010 FC87_RS05785 ribonucleosides salvage I tRNA ligase 37 degradation IV FC87_RS03280 a L-methionylaminoacyl- FC87_RS02250 [+ 2 isozymes] [+ 4 isozymes] hydroxymethyltransferase: glyA reductase threonylcarbamoyladenine FC87_RS04395 formate 967 (R)-4'- a tRNA Cys cys a (3R,5Z)-3- (R)-mevalonate tetrahydrodipicolinate thymidylate subunit beta: Inorganic Nutrient 1-oleoyl-2-palmitoyl- 3'-dephospho-CoA tRNA a 5-methylcytosine long chain subunit alpha: cytidine in tRNA S-methyl-5'- oxaloacetate acetate phosphopantothenate hydroxytetracos- 5-phosphate malonyl-CoA 4-hydroxy- L-alanine synthase: GMP FC87_RS03885 AMP Metabolism phosphatidylglycerol in 16S rRNA polyphosphate gly FC87_RS00905 thioadenosine 5-enoyl-[acp] tetrahydrodipicolinate biosynthesis III FC87_RS04010 5'-methylthioadenosine/ glycine-- multifunctional 2',3'- urea cycle RS01975 reductase: dCDP S-adenosylhomocysteine dTMP dTMP tRNA ligase cyclic-nucleotide 2'- RS00345 a 2,3,4-saturated peptidoglycan peptidoglycan 38- a (6Z)-3- FC87_RS01115 L-phenylalanine cys gly phosphodiesterase/ nucleosidase: a uridine a phosphate dTMP kinase: UDP kinase: dTMP kinase: uridine subunit alpha: CTP 1,2-diacyl-sn- tetrapeptide, tetrapeptide, an acyl- a DNA segment spermidine a cytosine in DNA ethylphosphate (S)-2,3,4,5- biosynthesis I cysteine CMP 5'-nucleotidase/ FC87_RS03185 a tRNA precursor CTP ATP coenzyme A 40 in tRNA oxooctadec- monoester FC87_RS00860 FC87_RS03865 FC87_RS00860 FC87_RS03880 Glycolysis arg carrier protein tetrahydrodipicolinate Gly MTR glycerol 3-phosphate glycan chain 1 glycanL,D- chain 2 holo-ACP recombinase RarA: tRNA spermidine 6-enoyl-[acp] desulfurase NifS: uridine kinase: a glycyl-[tRNA ] 3'-nucleotidase: CCA tRNA phosphatidate DNA methylase: beta-ketoacyl- alkaline alkaline chorismate Metabolic Regulator dCTP dTDP transpeptidase: FC87_RS04705 pseudouridine(38- 2,3,4,5- FC87_RS03190 dTDP FC87_RS02390 Gly FC87_RS02985 cytidylyltransferase: synthase CitX: acetyltransferase: phosphatase: phosphatase: Biosynthesis a tRNA nucleotidyltransferase: 40) synthase TruA: FC87_RS02145 ACP reductase: RS05350 L-asparagine glycolysis III (from glucose) argininosuccinate ammonium FC87_RS03695 peptidoglycanFC87_RS04475 FC87_RS04245 recombinase RarA: FC87_RS06090 tetrahydropyridine- ala UDP kinase: UDP kinase: UMP [+ 2 isozymes] a tRNA FC87_RS04000 FC87_RS01590 FC87_RS06040 FC87_RS06040 biosynthesis III a CDP-2,3,4-saturated- FC87_RS00295 FC87_RS04830 1 RS05625 2,6-dicarboxylate N- adenosine lyase: D-ala DAP-DAP acyl-carrier protein 3',5'-ADP 38- N - a 5-methylcytosine a (3R,6Z)-3- ppGpp biosynthesis FC87_RS03865 FC87_RS03865 containing a a DNA segment in a pseudouridine an alcohol (tRNA-dependent) prephenate FC87_RS06235 carbamoyl- diacylglycerol acetylspermidine in DNA ethanol acetyltransferase: D-glucopyranose 3' CCA end crosslink reverse orientation 40 in tRNA hydroxyoctadec- dTTP dTTP phosphate 6-enoyl-[acp] FC87_RS01100 asp adenosine pppGpp methionine-- glucokinase: deaminase: UTP and CTP dephosphorylation I L-arginino- synthase: met L-ornithine L-2-acetamido-6- GTP pyrophosphokinase: tRNA ligase: FC87_RS02360 FC87_RS05330 succinate FC87_RS02005 RS04070 RNase III mRNA β an (11Z)-3- oxoheptanedioate FC87_RS03805 FC87_RS05940 10 an L-methionyl- -D-fructofuranose an aliphatic an organic phosphoenol keto- an L-methionyl- D-glucopyranose UTP [+ 3 isozymes] an N - a peptide with a propanoyl-CoA phosphate an mRNA spermidine RS00600 an L-aspartyl- guanosine 3'-diphosphate Met processing 1-phosphate α,ω-diamine oxooctadec- hydroperoxide pyruvate GTP pyrophosphokinase: [initiator tRNA Met ] 6-phosphate formyltetrahydrofolate [initiator tRNA ] leader sequence [tRNA Asn ] phenylpyruvate inosine carbamoyl substrate fructose- 11-enoyl-[acp] FC87_RS03065 5'-triphosphate 3'- Fatty Acid and Lipid Biosynthesis Met methionyl-tRNA phosphate mRNA spermidine spermidine initiator tRNA glucose-6- CTP synthase: ribonuclease III: signal peptidase beta-ketoacyl- thiol peroxidase: pyruvate kinase: aromatic amino acid diphosphatase: phosphate formyltransferase: acyltransferase: bisphosphate interferase PemK: acetyltransferase: acetyltransferase: aspartyl/glutamyl- phosphate FC87_RS05870 argininosuccinate FC87_RS02200 I: FC87_RS04260 ACP reductase: FC87_RS00725 FC87_RS03920 aminotransferase: FC87_RS03805 FC87_RS02255 RNase III FC87_RS02210 aldolase: FC87_RS05820 FC87_RS06090 FC87_RS06090 N-acetyl-L,L-2,6- tRNA(Asn/Gln) fatty acid elongation -- saturated synthase: an N-formyl- FC87_RS01590 FC87_RS05065 CDP-diacylglycerol biosynthesis III isomerase: pgi UMP an mRNA fragment processing a leader sequence a peptide propanoyl FC87_RS02130 8 RS03005 diaminopimelate amidotransferase gondoate biosynthesis biotin-carboxyl carrier cyclopropane L-methionyl- a tetrahydrofolate N - an aliphatic N- a (3R,11Z)-3- CTP FC87_RS06230 product mRNA phosphate an mRNA fragment an alcohol pyruvate arg RS03555 arg N-acetyldiaminopimelate subunit C: aromatic amino acid (anaerobic) protein assembly fatty acid (CFA) F6P multifunctional 2',3'- L-citrulline [initiator tRNA met ] D-glyceraldehyde DHAP acetylspermidine acetyl-diamine hydroxyoctadec- aminotransferase: GTP ppGpp an acetoacetyl-[acp] DHAP biosynthesis cyclic-nucleotide 2'- 11-enoyl-[acp] deacetylase: FC87_RS04760 an acyl-[acyl- a [biotin carboxyl- hypoxanthine FC87_RS01105 FC87_RS03530 a malonyl-[acp] an oleoyl-[acp] a [phospholipid] phosphodiesterase/ an L-asparaginyl- glycerol-3- carrier protein] carrier protein]-L-lysine arg arg (11Z)-3-oxo- olefinic fatty acid CMP 5'-nucleotidase/ L,L- [tRNA Asn ] UDP kinase: GTP pyrophosphokinase: phosphate biotin--[acetyl- cyclopropane- a [protein] N-terminal- a dipetide with an N- a peptide with a [protein]-L- RS00470 RS06410 phe acyl phosphate icos-11-enoyl- β 3'-nucleotidase: nicotinate PRPP an mRNA a folate a quinone oxaloacetate diaminopimelate CoA-carboxylase] fatty-acyl- -D-fructose 1,6- multifunctional 2',3'- DL-allothreonine a tRNA precursor terminal L-aspartate an N-terminal methionine aminoacyl-tRNA FC87_RS03865 FC87_RS03805 dehydrogenase: synthase: FC87_RS02985 formyl-L-methionine agmatine agmatine [acp] synthase: phospholipid bisphosphate cyclic-nucleotide 2'- nicotinate peptide dipeptidase: L-proline peptide- diaminopimelate hydrolase: GTP pyrophosphokinase: guanosine-3',5'- FC87_RS00735 FC87_RS02210 ligase: serine ribonuclease Z: mRNA prolyl dihydrofolate NADPH:quinone malate a 3-oxoacyl-[acp] an (11Z)-3-FC87_RS01595 synthase: [+ 2 isozymes] phosphoribosyltransferase: deformylase: FC87_RS04565 methionine (R)-S- FC87_RS05815 FC87_RS03065 bis(diphosphate) FC87_RS01630 xanthine phosphodiesterase/ hydroxymethyltransferase: glyA FC87_RS03370 interferase PemK: aminopeptidase: reductase: reductase: dehydrogenase: RS02725 epimerase: sn-glycerol oxo-icos-11- FC87_RS01840 FC87_RS01030 FC87_RS03245 3'-diphosphatase: an acyl phosphate a [biotin carboxyl- a [phospholipid] fructose- 5'-nucleotidase/ uridine a single-stranded [+ 3 isozymes] FC87_RS05820 FC87_RS05325 FC87_RS04015 oxide reductase: FC87_RS05395 FC87_RS06165 FC87_RS06265 3-phosphate enoyl-[acp] gly acetaldehyde mature tRNA an N-terminal L- asn FC87_RS03805 carrier protein]-N fatty acid containing bisphosphate 3'-nucleotidase: NaMN oligoribonucleotide formate a proteinogenic a protein-L-FC87_RS01910 beta-ketoacyl- 6 methionyl-[protein] asp a peptide pro RS03820 meso- -biotinyl-L-lysine aldolase: FC87_RS02985 amino acid an mRNA fragment a 7,8-dihydrofolate a semiquinone pyruvate GDP ACP reductase: cyclopropane methionine- diaminopimelate acyl-phosphate FC87_RS02130 beta-ketoacyl- FC87_RS01590 [+ 2 isozymes] (R)-S-oxide diaminopimelate glycerol 3- a (3R,11Z)-3- urate ACP reductase: phosphate cytidine RS05855 decarboxylase: β-ketoacyl- hydroxy-icos- a [biotin carboxyl- FC87_RS01590 triose-phosphate 3 α-D-ribose- D-glucopyranose FC87_RS01095 acyltransferase: 11-enoyl-[acp] carrier-protein dimer]- 5-amino-4- an (R)-2- an N -methyladenine an (R)-2- 15-cis-4,4'- β-D-fructose 2,6- ACP synthase: isomerase: PRPP putrescine a tRNA sec ser ethanol RS01285 FC87_RS01890 6 imidazolecarboxyamide halocarboxylate in DNA halocarboxylate 1-phosphate diapophytoene bisphosphate 6-phosphate FC87_RS01575 a (3R)-3- (3R,11Z)-3- N -biotinyl-L-lysine FC87_RS00665 lys a 2,3,4-saturated D-glyceraldehyde adenine HAD family 3-methyladenine HAD family spermidine dehydrosqualene serine-- fructose-2,6- sugar- hydroxyacyl-[acyl- hydroxy-icos- acetyl-CoA DHAP phosphopentomutase: catalase: fatty acyl-[acp] a 1-acyl-sn acetyl-CoA 3-phosphate phosphoribosyltransferase: hydrolase: DNA glycosylase: hydrolase: acetyltransferase: desaturase: tRNA ligase: bisphosphatase: phosphatase: 3-hydroxyacyl-carrier protein] 11-enoyl-[acp] carboxylase FC87_RS03385 FC87_RS02460 FC87_RS05730 FC87_RS02460 FC87_RS01770 FC87_RS03360 -glycerol 3- carboxylase: glyceraldehyde- FC87_RS06090 FC87_RS05630 FC87_RS05095 FC87_RS05210 FC87_RS05890 [acp] dehydratase: biotin carboxylase an (S)-2- an apurinic site an (R)-2- an L-seryl- RS02645 phosphate FC87_RS01935 3-phosphate AICAR a halide anion 3-methyladenine a halide anion D-ribose 5- all-trans-4,4'- [+ 2 isozymes] dehydratase: FC87_RS01570 subunit: hydroxycarboxylate within DNA hydroxyacid N-acetylputrescine [tRNA sec ] D-glucopyranose acetaldehyde 1-acyl-sn-glycerol- [+ 2 isozymes] dehydrogenase: phosphate diapophytofluene F6P RS01235 FC87_RS01570 a (2E,11Z)-icosa- FC87_RS01610 3-phosphate FC87_RS00675 acyltransferase: 2,11-dienoyl-[acp] a [carboxyl-carrier protein dimer]-N 6 - FC87_RS03650 (2E,11Z)-icosa- 13-DPG a 1,2-diacyl- carboxybiotinyl-L-lysine a 2-deoxy-D- an (S)-2- a single a ribonucleoside a β-D-galactoside D-glucopyranose RS00685 2,11-dienoyl- a nucleobase a uracil in DNA O-ureido-L- asp spermine wound RNA 5-methylcytosine MeOH sn-glycerol ribosyl-base halocarboxylate stranded DNA triphosphate 2,3,4-saturated- a trans-2- [acp] reductase: phosphoglycerate nucleoside 2- HAD family uracil-DNA homoserine a 2,3,4-saturated 3-phosphate DNA primase: argininosuccinate spermidine galactoside O- sugar DNA/RNA cytosine RS01965 fatty-acid-[acp] enoyl-[acyl- FC87_RS01625 kinase: deoxyribosyltransferase: hydrolase: glycosylase: catalase: fatty acyl-[acp] phosphatidate FC87_RS03890 synthase: acetyltransferase: acetyltransferase: dehydrogenase: helicase: deaminase: reductase: carrier protein] FC87_RS00670 FC87_RS05170 FC87_RS02460 ssDNA/pppN(pN) FC87_RS00640 FC87_RS03360 cytidylyltransferase: FC87_RS06230 FC87_RS06090 FC87_RS05500 FC87_RS01275 FC87_RS00775 FC87_RS01555 FC87_RS01595 a gondoyl-[acp] a 2-deoxy-D- an (S)-2- hybrid an apyrimidinic a 6-acetyl-β- FC87_RS03695 3-phospho-D-glycerate a nucleobase a halide anion n -1 uracil canavaninosuccinate D-glucono- thymine ribosyl-base hydroxycarboxylate site in DNA N 1 -acetylspermine D-galactoside 1,5-lactone an unwound RNA formaldehyde RS04670 a CDP- 2,3,4-saturated RS00765 diacylglycerol fatty acyl- a 5S rRNA 34 nicotinate adenine a [protein]-L- D-mannitol [acp]:NAD+ acetoacetyl-CoA H O acetyl-CoA canavaninosuccinate a tripeptide a cytidine lys SAICAR a sugar phosphate 5-fluorocytosine 2-phospho-D-glycerate 2 precursor Ile2 dinucleotide proline (ω = 180) 1-phosphate oxidoreductase: in tRNA adenylosuccinate hydroxymethylglutaryl-CoA ribonuclease M5: argininosuccinate peptidase T: tRNA(Ile)-lysidine sugar- peptidylprolyl cytosine sugar- FC87_RS01625 NAD(+) synthase: lyase: RS02080 phosphopyruvate synthase: FC87_RS03535 FC87_RS05930 lyase: FC87_RS06235 FC87_RS05370 synthetase: phosphatase: isomerase: deaminase: phosphatase: hydratase: a double-stranded a proteinogenic FC87_RS01025 FC87_RS01550 FC87_RS05890 FC87_RS05890 RS06260 HMG-CoA a mature 5S-rRNA fumarate L-canavanine a dipeptide FC87_RS05790 FC87_RS02580 FC87_RS01555 oligonucleotide a lysidine 34 FC87_RS00660 amino acid AICAR fumarate a [protein]-L- 5-fluorouracil Ile2 NAD + a sugar D-mannitol in tRNA ω phosphoenolpyruvate proline ( = 0)

pyruvate kinase: RS04615 FC87_RS03920

pyruvate

an amino an amino RS06005 acid acid phosphate a branched- a branched- a branched- an amino an amino phosphonate a polar chain chain chain phosphate spermidine a nucleotide a macrolide D-fructose acid acid (RS)-malate (RS)-malate a nucleoside amino acid D-gluconate uracil a phospholipid amino acid amino acid amino acid putrescine predicted predicted predicted ABC ABC predicted ABC ABC RS03490 RS04590 RS01145 RS05375 RS04655 RS01405 RS01225 RS00330 RS02670 RS00920 RS04270 RS02690 RS01860 RS00570 RS05465 RS02965 RS03585 RS03540 RS00300 RS02380 RS02875 RS01320 RS03760 RS01960 RS05710 RS04425 RS03545 transporter transporter RS01450 RS04430 RS01835 RS06160 RS04445 RS01775 transporter of RS01130 RS04610 RS06190 RS04400 RS03180 RS01655 RS04465 RS06280 RS05430 RS00550 RS01660 RS02190 RS01230 RS05090 RS02955 RS05620 RS00245 RS01500 RS03830 RS01525 RS04095 transporter of an of an phosphonate of phosphate amino acid amino acid

a phospholipid

a branched- a branched- a branched- uracil a nucleotide a macrolide D-fructose an amino an amino an amino an amino (RS)-malate (RS)-malate a nucleoside phosphonate a polar D-gluconate spermidine chain chain chain phosphate phosphate acid acid acid acid amino acid putrescine amino acid amino acid amino acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.