An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000220065-HmpCyc: Streptococcus sp. oral taxon 056 F0418 Cellular Overview Connections between pathways are omitted for legibility. uracil D-cellobiose lactose D-cellobiose D-cellobiose D-cellobiose D-cellobiose D-cellobiose D-cellobiose phosphate lactose lactose lactose lactose lactose lactose

predicted predicted PEP-driven ABC RS04025 RS06130 RS03150 RS03110 RS06940 RS04490 RS00455 RS03415 RS01105 RS04075 RS01770 RS05080 RS00785 RS03215 RS00280 RS05205 RS02055 RS08805 RS09480 RS01985 RS03250 RS06455 RS00275 RS01135 RS04060 RS07960 RS09615 RS00485 RS06785 RS02405 RS09790 RS05525 RS06150 RS09440 RS04970 RS02350 RS07955 RS03970 RS02365 RS08260 RS07540 RS03875 RS08620 RS05150 RS02370 RS02435 RS08255 RS09235 RS08520 RS08760 RS08765 RS02310 RS06475 RS03450 RS07565 RS04525 RS01240 RS00400 RS09245 RS04950 RS07880 RS07545 RS07470 RS04130 transporter RS07475 RS02780 RS01205 RS01935 RS03525 RS05060 RS07890 RS02900 RS01115 RS09295 RS08825 RS03545 RS06565 RS07505 RS00300 RS06160 RS05430 RS04755 RS03500 RS07370 RS01565 RS01545 RS01520 RS07930 RS05645 RS05120 RS00795 RS01610 RS06625 RS02525 RS09200 RS08240 RS06295 RS06770 RS00515 RS00385 RS08235 RS01375 RS07595 RS01855 RS08720 RS05565 RS08715 transporter of D- of phosphate RS00755 cellobiose RS01345 uracil D-cellobiose 6'-phosphate lactose 6'- D-cellobiose 6'-phosphate D-cellobiose 6'-phosphate D-cellobiose 6'-phosphate D-cellobiose 6'-phosphate D-cellobiose 6'-phosphate lactose 6'-phosphate phosphate lactose 6'-phosphate lactose 6'-phosphate lactose 6'-phosphate lactose 6'-phosphate lactose 6'-phosphate D-cellobiose phosphate RS06710 6'- RS04635 phosphate

RS06635 RS01845 Respiration Carbohydrate Degradation Secondary Metabolite Degradation RS05355 Secondary Metabolite Biosynthesis undecaprenyldiphospho- undecaprenyl- a plant soluble a long-linear a (1->4)- an N-acetyl-β- 5'-deoxy-5'- a (3R,5Z)-3- a uracil 1939 a debranched a (6S)-5- α-D- a cis-delta11-3- a [protein]-L- superpathway of pyrimidine Nucleoside and Nucleotide Biosynthesis Fatty Acid and Lipid Biosynthesis 2-oxoisovalerate decarboxylation to isobutanoyl-CoA autoinducer AI-2 degradation N-acetylmuramoyl-L- diphospho-N- glu heteroglycan a purine α-D-glucan α-D-glucan D-hexosaminide fluoroadenosine hydroxy-tetradec- in 23S rRNA α-limit dextrin methionine inosine-5'-phosphate biosynthesis I superpathway of pyrimidine deoxyribonucleoside salvage D-galactose degradation I (Leloir pathway) chitin degradation II (Vibrio) UDP-N-acetyl- formyltetrahydrofolate arsenate glucopyranose ATP oxo-C30:1-[acp] dGTP deoxyribonucleotides de novo biosynthesis autoinducer AI-2 biosynthesis I Carbohydrate Biosynthesis alanyl-γ-D-glutamyl-meso acetylmuramoyl- UDP-N-acetyl- glycogen/starch/ ribonucleoside glycogen/starch/ glycogen/starch/ beta-N- purine-nucleoside 5-enoyl-[acp]3-oxoacyl-[acyl-carrier- 3-oxoacyl-ACP reductase: 23S rRNA glycogen/starch/ peptide-methionine an [apo BCAA α-D-glucosamine bifunctional 1-phosphate AI-2 RS07115 AI-2 RS04975 -2,6-diaminopimeloyl- γ α alpha-glucan family purine-nucleoside alpha-glucan family alpha-glucan family acetylhexosaminidase: phosphorylase: glucose-1-phosphate (uracil(1939)-C(5))- alpha-glucan family (R)-S-oxide reductase: 2'-deoxycytidine palmitate biosynthesis II (bacteria and plants) dehydrogenase β-D-galactose AI-2 L-alanyl- -D- -D-glucosamine folylpolyglutamate synthase/ protein] reductase: HMPREF9182_RS08895 nucleoside-triphosphate AIR phosphatidylglycerol chitin UDP-N-acetylglucosamine- phosphorylase: phosphorylase: phosphorylase: phosphorylase: HMPREF9182_RS04455 HMPREF9182_RS02190 methyltransferase RlmD: phosphorylase: HMPREF9182_RS07460 gln hydrogencarbonate UDP-N-acetyl-D- acyl-[acyl-carrier protein] 6 D-alanyl-D-alanine UDP-N-acetylglucosamine- glutamyl-L-lysyl- adenylyltransferase: HMPREF9182_RS03665 3-oxoacyl-[acyl-carrier- diphosphatase: SAM UDP-α-D-galactose E2 protein] N branched-chain alpha- autoinducer-2 kinase: dihydrofolate synthase: HMPREF9182_RS06680 HMPREF9182_RS02190 dTDP-L-rhamnose biosynthesis I biosynthesis II (non-plastidic) pathway galactose mutarotase: D-alanyl-D-alanine -N-acetylmuramyl- HMPREF9182_RS06680 HMPREF9182_RS06680 beta-N- purine-nucleoside HMPREF9182_RS08600 protein] reductase: HMPREF9182_RS04185 HMPREF9182_RS06680 peptide-methionine HMPREF9182_RS03590 5-(carboxyamino)imidazole cytidine deaminase: glucosamine biosynthesis I biosynthesis -lipoyl-L-lysine keto acid dehydrogenase HMPREF9182_RS07130 -N-acetylmuramyl- HMPREF9182_RS04990 3-oxoacyl-ACP reductase: an acetoacetyl-[acp] (4S)-4-hydroxy-5- (pentapeptide) glycogen/starch/alpha- purine-nucleoside glycogen/starch/alpha- glycogen/starch/alpha- acetylhexosaminidase: phosphorylase: 23S rRNA glycogen/starch/alpha- (R)-S-oxide reductase: RS03765 ribonucleotide synthase: HMPREF9182_RS00865 subunit E2: HMPREF9182_RS06120 (pentapeptide) glucose-1-phosphate a (5Z)-3-oxo- HMPREF9182_RS08895 a cis-delta11-3-HMPREF9182_RS03665 RS03190 carbamoyl phosphate D-glucopyranose α-D-glucopyranose DHAP an acyl-[acyl- dihydrolipoyl phosphooxypentane- pyrophosphoryl- bifunctional glucan phosphorylase: phosphorylase: HMPREF9182_RS06465 α pyrophosphoryl- glucan phosphorylase: glucan phosphorylase: HMPREF9182_RS02195 adenylyltransferase (uracil(1939)-C(5))- glucan phosphorylase: a protein-L-HMPREF9182_RS00315 dGMP HMPREF9182_RS05495 dCMP 6-phosphate UDP- -D-glucose HMPREF9182_RS00665 α-D-galactose 2,3-dione folylpolyglutamate synthase/ HMPREF9182_RS02195 an N-acetyl-β- tetradec-5- hydroxyC30:1- synthase large subunit: SAH glucose-6- 1-phosphate 3-oxoacyl-ACP reductase: NAD(P)H-dependent carrier protein] dehydrogenase: undecaprenol N- undecaprenol N- HMPREF9182_RS08615 HMPREF9182_RS08615 HMPREF9182_RS08615 5-fluoro-5- subunit GlgD: methyltransferase RlmD: HMPREF9182_RS08615 2'-deoxyuridine glucose-1-phosphate UDP-glucose 4- acyl-ACP thioesterase: a chitodextrin dihydrofolate synthase: α α-D- α-D- an alcohol enoyl-[acp] [acp] α-D- methionine- HMPREF9182_RS00680 N5-CAIR (d)CMP kinase: phosphate HMPREF9182_RS08895 glycerol-3-phosphate HMPREF9182_RS00660 acetylglucosamine -D-glucopyranose a plant soluble ribose-1-arsenate a purine base a long-linear a (1->4)- D-hexosamine deoxy-D-ribose adenine HMPREF9182_RS08605 HMPREF9182_RS09445 thymidylyltransferase: epimerase GalE: HMPREF9182_RS02065 acetylglucosamine HMPREF9182_RS05305 a 5- (R)-S-oxide asp 5'-methylthioadenosine/ : pgi 3-oxoacyl-[acyl-carrier- dehydrogenase: galactokinase: ditrans,octacistransferase:- 1-phosphate heteroglycan glucopyranose α glucopyranose α 1-phosphate ADP-α-D-glucose glucopyranose HMPREF9182_RS01100 an [apo BCAA : a (6S)-5- -D-glucan -D-glucan 1939 RS01010 5-(carboxyamino)imidazole thymidine kinase: HMPREF9182_RS01130 HMPREF9182_RS01390 HMPREF9182_RS06935 a fatty acid an [apo BCAA dehydrogenase HMPREF9182_RS01405 undecaprenyldiphospho- 1-phosphate 1-phosphate methyluracil 1-phosphate RS03455 carbamoyl adenosylhomocysteine F6P dTDP-α-D-glucose UDP-α-D-galactose protein] reductase: dehydrogenase 3-hydroxy-5- lipid IIHMPREF9182_RS03100 (meso HMPREF9182_RS03100 formyltetrahydrofolate ribonucleotide mutase: HMPREF9182_RS00545 dCDP guanine and sn-glycerol E2 protein] N 6 -S-[2- N-acetyl-(N-acetyl-β-D- in 23S rRNA 6 phosphooxypentane- UDP phosphate guanosine salvage II nucleosidase: HMPREF9182_RS03665 E2 protein] N α-D-galactose diaminopimelate containing) UDP HMPREF9182_RS05500 thymidine glutamine--fructose-6- dTDP-glucose a (3R)-3- 3-phosphate methylpropanoyl]dihydrolipoyl- UDP-α-D-glucose a chitodextrin glucosaminyl)muramoyl- dUMP HMPREF9182_RS08935 -dihydrolipoyl- 2,4-dione phosphate transaminase 4,6-dehydratase: glycerol-3-phosphate 1- L-lysine 1-phosphate L-alanyl-γ-D-glutamyl-L- asp hydroxybutanoyl- L-lysine 3-hydroxy-5- aspartate CAIR (isomerizing): HMPREF9182_RS01120 lysyl-D-alanyl-D-alanine RS06435 thymidylate synthase: thymidine kinase: guanosine S-ribosyl-L-homocysteine [acp] O-acyltransferase PlsY: phosphonooxypentane- RS04905 carbamoyltransferase dCTP HMPREF9182_RS04415 HMPREF9182_RS00725 HMPREF9182_RS00545 dTDP-4-dehydro- (3R)-3-hydroxybutanoyl- HMPREF9182_RS02145 2,4-dione thiolase: catalytic subunit: phosphoribosylaminoimidazolesuccinocarboxamide S-ribosylhomocysteine D-glucosamine 6-deoxy-α-D- [acyl-carrier protein] a 1-acyl-sn branched-chain alpha- HMPREF9182_RS07120 β a (9Z)-3-oxo- HMPREF9182_RS00780 -glycerol 3- a glycogen maltohexaose maltotetraose a peptide with a 5'-chloro-5'- methyl -D-glucoside a cis-delta15-3- a kanamycin synthase: HMPREF9182_RS06045 : 6-phosphate glucopyranose dehydratase: keto acid dehydrogenase beta-N- a palmitoyl-[acp] a malonyl-[acp] an acetyl-[acp] a malonyl-[acp] a purine a [protein] Ser/Thr octadec-9- phosphate leader sequence deoxyadenosine 6-phosphate oxo-C34:1-[acp] formate GTP biotin ATP dATP biotin RS02565 biotin guanine HMPREF9182_RS03815 phosphoglucosamine dTDP-4-dehydrorhamnose HMPREF9182_RS03650 subunit E2: acetylhexosaminidase: DHAP glycogen/starch/ glycogen/starch/alpha- glycogen/starch/alpha- ribonucleoside HPr kinase/phosphorylase: purine-nucleoside 6-phospho-beta- enoyl-[acp] aminoglycoside RS06880 N-carbamoyl- guanine and 1-acyl-sn-glycerol-3- 3-oxoacyl-[acyl-carrier- 3-oxoacyl-[acyl-carrier- signal peptidase I: 3-oxoacyl-[acyl-carrier- 3-oxoacyl-ACP reductase: anaerobic ribonucleoside- dTMP superpathway of pyrimidine mutase: 3,5-epimerase: HMPREF9182_RS00665 HMPREF9182_RS06465 alpha-glucan family glucan phosphorylase: glucan phosphorylase: purine-nucleoside HMPREF9182_RS02800 phosphorylase: glucosidase: bifunctional biotin-- phosphotransferase: SAICAR guanosine salvage AI-2 a (2E)-but- phosphate acyltransferase: protein] reductase: protein] reductase: HMPREF9182_RS03165 protein] reductase: HMPREF9182_RS08895 nucleoside-triphosphate L-aspartate nucleobases salvage hypoxanthine HMPREF9182_RS01515 HMPREF9182_RS01125 beta-N- phosphorylase: HMPREF9182_RS08615 HMPREF9182_RS08615 phosphorylase: HMPREF9182_RS02190 HMPREF9182_RS08495 triphosphate reductase: HMPREF9182_RS03220 dTMP kinase: 2-enoyl-[acp] HMPREF9182_RS03255 HMPREF9182_RS03665 HMPREF9182_RS03665 signal peptidase I: serine/threonine HMPREF9182_RS03665 3-oxoacyl-[acyl-carrier- [acetyl-CoA-carboxylase] diphosphatase: phosphoribosyltransferase: D-glucosamine dTDP-4-dehydro- acetylhexosaminidase: HMPREF9182_RS06680 HMPREF9182_RS02190 HMPREF9182_RS05285 RS08090 dihydroorotase: adenylosuccinate lyase: HMPREF9182_RS08670 uracil a 1,2-diacyl- glycogen/starch/ glycogen/starch/ HMPREF9182_RS07355 protein kinase: purine-nucleoside 6-phospho-beta- protein] reductase: synthetase/biotin aminoglycoside HMPREF9182_RS03590 guanosine ribonucleotides β-L-rhamnose crotonyl-[acyl-carrier- beta-ketoacyl-[acyl-carrier- beta-ketoacyl-[acyl-carrier- 3-oxoacyl-ACP reductase: dGTP HMPREF9182_RS02150 HMPREF9182_RS05475 uracil guanosine HMPREF9182_RS05790 1-phosphate sn-glycerol N,N'- HMPREF9182_RS04455 N,N',N''- glycogen/starch/alpha- alpha-glucan family alpha-glucan family purine-nucleoside HMPREF9182_RS03775 phosphorylase: glucosidase: operon repressor: phosphotransferase: de novo biosynthesis dTDP protein] reductase: protein] synthase II: protein] synthase II: a leader sequence a peptide a (3R,9Z)-3- HMPREF9182_RS08895 a cis-delta15-3-HMPREF9182_RS03665 RS03045 phosphoribosyltransferase: purine-nucleoside xanthine bifunctional UDP-N- dTDP-4-dehydrorhamnose 3-phosphate diacetylchitobiose triacetylchitotriose glucan phosphorylase: phosphorylase: phosphorylase: phosphorylase: a [protein] (L-serine/L- HMPREF9182_RS02195 HMPREF9182_RS09510 HMPREF9182_RS01450 HMPREF9182_RS04020 dAMP (2R,4S)-2-methyl-2,4- HMPREF9182_RS03665 HMPREF9182_RS03660 HMPREF9182_RS03660 β hydroxy-octadec- hydroxyC34:1- biotinyl-5'- a kanamycin (S)-dihydroorotate AICAR HMPREF9182_RS03375 phosphorylase: phosphoribosyltransferase: acetylglucosamine reductase: Glycolysis beta-N- a 3-oxooctadecanoyl- HMPREF9182_RS08615 HMPREF9182_RS06680 HMPREF9182_RS06680 HMPREF9182_RS02195 threonine) phosphate 5-chloro-5- -D-glucose dihydroxydihydrofuran-3-one acyl-carrier protein an acetoacetyl-[acp] acyl-carrier protein α α α α-D-ribose- MeOH 9-enoyl-[acp] [acp] adenylate 3'-phosphate IMP HMPREF9182_RS02195 HMPREF9182_RS00530 diphosphorylase/ HMPREF9182_RS00380 a butanoyl-[acp] acetylhexosaminidase: [acp] -D-glucopyranose -D-glucopyranose -D-glucopyranose a purine base adenine deoxyribose 6-phosphate RS04960 bifunctional bifunctional pyr operon an α-limit dextrin maltopentaose maltotriose 1-phosphate dihydroorotate oxidase: glucosamine-1-phosphate β HMPREF9182_RS04455 1-phosphate 1-phosphate 1-phosphate 1-phosphate phosphoribosylaminoimidazolecarboxamide dTTP transcriptional regulator/uracil purine-nucleoside dTDP- -L-rhamnose a CDP- glycolysis III (from glucose) RS02790 HMPREF9182_RS07455 GMP N-acetyltransferase GlmU: 3-oxoacyl-[acyl-carrier- formyltransferase/IMP cyclohydrolase phosphoribosyltransferase phosphorylase: diacylglycerol beta-N- (2R,4S)-2-methyl-2,3,3,4- HMPREF9182_RS08920 protein] reductase: PyrR: HMPREF9182_RS00790 HMPREF9182_RS02190 acetylhexosaminidase: 4 orotate PRPP PurH: HMPREF9182_RS06075 CDP-diacylglycerol-- D-glucopyranose an inactive a linear malto- a (7Z,10Z,13Z,16Z N -(β-N-acetyl- 1915 a (7Z)-3- 22 XMP guanine tetrahydroxytetrahydrofuran N-acetyl-α-D- PRPP biosynthesis HMPREF9182_RS03665 UDP-glucose-- a glutaryl-[acp] a maltodextrin a pseudouridine a 3-oxohexacosanoyl- chitin a cis-delta21-3- an adenine a double UMP UDP-glucose 4- HMPREF9182_RS06465 acetyl-CoA RS08975 xanthine and glycerol-3-phosphate 3- ribonucleoside a reduced a malonyl-[acp] oligosaccharide ,19Z)-3-oxodocosa- D-glucosaminyl) hypoxanthine PRPP in 23S rRNA oxohexacos- in tRNA stranded DNA GTP orotate FAICAR glucosamine beta-ketoacyl-[acyl-carrier- glucokinase: hexose-1-phosphate N-acetyl-D- SAM methyl ester glycogen/starch/ glycogen/starch/ [acp] beta-N- oxo-C40:1-[acp] UMP kinase: xanthosine salvage D-ribose 5- phosphatidyltransferase: epimerase GalE: triphosphate flavodoxin 3-oxoacyl-[acyl-carrier- 7,10,13,16,19-pentaenoyl-[acp]3-oxoacyl-ACP reductase: -L-asparagineN(4)-(beta-N- 23S rRNA 3-oxoacyl-ACP reductase: 7-enoyl-[acp]3-oxoacyl-ACP reductase: 3-oxoacyl-ACP reductase: tRNA (adenine(22)-N(1))- type II restriction acetyl-CoA carboxylase RS05445 phosphoribosyltransferase: xanthosine-5'-phosphate:L- hypoxanthine 1-phosphate protein] synthase II: HMPREF9182_RS00730 uridylyltransferase: glucosamine anaerobic ribonucleoside- alpha-glucan family alpha-glucan family hypoxanthine acetylhexosaminidase: bifunctional HMPREF9182_RS09005 phosphate HMPREF9182_RS05940 HMPREF9182_RS01390 reductase protein] reductase: HMPREF9182_RS08895 acetylglucosaminyl) (pseudouridine(1915)-N(3) HMPREF9182_RS08895 HMPREF9182_RS08895 HMPREF9182_RS08895 methyltransferase TrmK: MunI: carboxyl transferase nucleoside-triphosphate glutamine amido- phosphoribosyltransferase: bifunctional UDP-N- ribose-phosphate HMPREF9182_RS03660 HMPREF9182_RS01395 triphosphate reductase phosphorylase: phosphorylase: phosphoribosyltransferase: HMPREF9182_RS04455 HMPREF9182_RS02175 1-(3-sn- D-glucopyranose HMPREF9182_RS03665 )-methyltransferase RlmH: HMPREF9182_RS01155 HMPREF9182_RS00620 subunit alpha: diphosphatase: phosphoribosylaminoimidazolecarboxamide (AMP-forming): (d)CMP kinase: HMPREF9182_RS05790 xanthosine acetylglucosamine α-D-glucopyranose lactose and galactose degradation I 3-oxoacyl-[acyl-carrier- -L-asparaginase: HMPREF9182_RS05790 3-oxoacyl-[acyl-carrier- 3-oxoacyl-[acyl-carrier- 3-oxoacyl-[acyl-carrier- diphosphokinase: a 3-oxohexanoyl- phosphatidyl) 6-phosphate activating protein: HMPREF9182_RS06680 HMPREF9182_RS06680 HMPREF9182_RS05860 beta-N- N 1 - a double HMPREF9182_RS03635 orotidine 5'- formyltransferase/IMP cyclohydrolase HMPREF9182_RS00625 HMPREF9182_RS01100 UDP-α-D-galactose an active beta-ketoacyl-[acyl-carrier- protein] reductase: HMPREF9182_RS02280 an N 3 - protein] reductase: protein] reductase: protein] reductase: HMPREF9182_RS03590 RS04825 xanthine diphosphorylase/ HMPREF9182_RS05635 1-phosphate HMPREF9182_RS05265 β xanthine 22 purine-nucleoside [acp] -sn-glycerol glucose-6- glycogen/starch/alpha- glycogen/starch/alpha- N-acetyl- - 1915 acetylhexosaminidase: methyladenine stranded DNA [+ 3 isozymes] phosphate PurH: HMPREF9182_RS06075 UDP lactose 6'- a flavodoxin ribonucleoside protein] synthase II: HMPREF9182_RS03665 asp methylpseudouridine HMPREF9182_RS03665 HMPREF9182_RS03665 HMPREF9182_RS03665 RS06580 phosphoribosyltransferase: glucosamine-1-phosphate ribose-phosphate 3-phosphate met 5'-deoxyadenosine glucan phosphorylase: a (3R,7Z,10Z,13Z,16Z phosphoribosyltransferase: a (3R)-3- HMPREF9182_RS06465 a (3R,7Z)-3- a cis-delta21-3- in tRNA with 5'-terminal phosphorylase: 3-oxoacyl-ACP reductase: fatty acid elongation -- saturated phosphate phosphate semiquinone triphosphate HMPREF9182_RS03660 glucan phosphorylase: glucosaminylamine in 23S rRNA malonyl-CoA GMP GMP HMPREF9182_RS00530 N-acetyltransferase GlmU: 6-phospho-beta- ,19Z)-3-hydroxydocosa- HMPREF9182_RS00530 hydroxyhexacosanoyl- N-acetyl-D- hydroxyhexacos- hydroxyC40:1- orotidine-5'-phosphate HMPREF9182_RS02190 diphosphokinase: HMPREF9182_RS08895 isomerase: pgi a 3-oxopimeloyl- HMPREF9182_RS08615 HMPREF9182_RS08615 chitin phosphate IMP HMPREF9182_RS08920 reductase acyl-carrier protein α α 7,10,13,16,19-pentaenoyl-[acp] [acp] glucosamine 7-enoyl-[acp] [acp] decarboxylase: HMPREF9182_RS00080 galactosidase: [acp] methyl ester -D-glucopyranose a linear malto- -D-glucopyranose IMP purine-nucleoside UDP-N-acetyl- 3-oxoacyl-[acyl-carrier- D-glucopyranose L-rhamnose degradation I a maltodextrin RS03895 HMPREF9182_RS02180 guanylate kinase: GMP PRPP an acetoacetyl-[acp] F6P HMPREF9182_RS08770 1-phosphate oligosaccharide 1-phosphate UTP phosphorylase: α protein] reductase: an L-1- 6-phosphate D-galactopyranose -D-glucosamine α-L- RS09350 UMP HMPREF9182_RS03805 HMPREF9182_RS02195 HMPREF9182_RS03665 phosphatidyl- 6-phosphate xanthine 6-phosphofructokinase: rhamnopyranose a (3R)-3- sn-glycerol HMPREF9182_RS03175 L-rhamnose mutarotase: galactose-6- UMP kinase: adenine 2503 an N-formyl-L- 6-(hydroxymethyl) a [2-oxoglutarate a 3- a (5Z)-3- adenine 37 a [lipoyl-carrier (3R,5S)-3- GDP adenine and xanthine hydroxyhexanoyl- phosphate isomerase: a malonyl-[acp] a (4Z)-hexadec- a glycogen a 3-oxotetracosanoyl- a cis-delta13-3- 6 β HMPREF9182_RS01660 a purine 2'- dehydrogenase E2 protein] oxodocosanoyl- val HMPREF9182_RS09005 CTP -D-fructose 1,6- β-L- in 23S rRNA a malonyl-[acp] a malonyl-[acp] methionylaminoacyl- -7,8-dihydropterin oxotetracos- in tRNA protein]-N -[(R) hydroxy-1- IMP RS02855 adenosine salvage I phosphoribosyltransferase: [acp] HMPREF9182_RS08735 methyl ester 4-enoyl-[acp] glycogen/starch/ 6 [acp] oxo-C32:1-[acp] 1 (d)CMP kinase: bisphosphate rhamnopyranose 23S rRNA 3-oxoacyl-[acyl-carrier- 3-oxoacyl-[acyl-carrier- tRNA peptide deformylase: 2-amino-4-hydroxy-6- deoxyribonucleoside N -dihydrolipoyl-L-lysine 3-oxoacyl-ACP reductase: [acp] 3-oxoacyl-ACP reductase: 5-enoyl-[acp]3-oxoacyl-ACP reductase: 3-oxoacyl-ACP reductase: tRNA1(Val) (adenine(37) -dihydrolipoyl]- pyrroline-5- RS01280 adenosine ribonucleotides HMPREF9182_RS00530 (3R)-3-hydroxyhexanoyl- galactose-6-phosphate alpha-glucan family purine-nucleoside dihydrolipoyl HMPREF9182_RS01100 superpathway of 5-aminoimidazole a 3-oxoacyl-[acp] (adenine(2503)-C(2))- protein] reductase: protein] reductase: HMPREF9182_RS04405 hydroxymethyldihydropteridine HMPREF9182_RS08895 HMPREF9182_RS08895 HMPREF9182_RS08895 HMPREF9182_RS08895 -N6)-methyltransferase: L-lysine carboxylate pyrimidine deoxyribonucleotides de novo biosynthesis [acyl-carrier protein] L-rhamnose isomerase: isomerase subunit LacB: phosphorylase: phosphorylase: dehydrogenase: dihydrolipoyl pyrroline-5- GMP reductase: ribonucleotide biosynthesis fructose-1,6-bisphosphate methyltransferase RlmN: HMPREF9182_RS03665 HMPREF9182_RS03665 diphosphokinase: HMPREF9182_RS03265 UDP biosynthesis from CTP adenosine dehydratase: HMPREF9182_RS01065 peptide deformylase: HMPREF9182_RS00660 3-oxoacyl-[acyl-carrier- 3-oxoacyl-[acyl-carrier- 3-oxoacyl-[acyl-carrier- 3-oxoacyl-[acyl-carrier- dehydrogenase: carboxylate reductase: XMP HMPREF9182_RS08740 HMPREF9182_RS04105 HMPREF9182_RS06680 HMPREF9182_RS04985 HMPREF9182_RS02190 an N 6 - HMPREF9182_RS00525 purine-nucleoside HMPREF9182_RS03650 aldolase, class II: beta-ketoacyl-[acyl-carrier- beta-ketoacyl-[acyl-carrier- HMPREF9182_RS07610 (7,8-dihydropterin- a [2-oxoglutarate protein] reductase: protein] reductase: protein] reductase: protein] reductase: HMPREF9182_RS00660 HMPREF9182_RS00805 D-tagatofuranose a 2-methyladenine 2503 a L-methionylaminoacyl- purine-nucleoside methyladenine 37 a [lipoyl-carrier RS04390 CTP PRPP IMP asp phosphorylase: Aminoacyl-tRNA Charging HMPREF9182_RS04370 keto-L-rhamnulose 5'-deoxyadenosine met protein] synthase II: protein] synthase II: glycogen/starch/alpha- 6-yl)methyl dehydrogenase E2 HMPREF9182_RS03665 HMPREF9182_RS03665 HMPREF9182_RS03665 HMPREF9182_RS03665 RS04505 GTP formate a (3R)-3- a (3R)-3- a (3R,5Z)-3- a cis-delta13-3- val protein]-N 6 - amidophosphoribosyltransferase: a (2E)-hex- 3-oxoacyl-[acyl-carrier- 6-phosphate in 23S rRNA glucan phosphorylase: tRNA phosphorylase: protein] N 6 -lipoyl-L-lysine in tRNA Hyp GMP adenylosuccinate synthase: HMPREF9182_RS02195 HMPREF9182_RS03660 HMPREF9182_RS03660a (6Z)-3- diphosphate hydroxytetracosanoyl- hydroxydocosanoyl- hydroxytetracos- hydroxyC32:1- 1 2-enoyl-[acp] protein] reductase: tagatose-6- HMPREF9182_RS08615 2-deoxy-α- HMPREF9182_RS02195 lipoyl-L-lysine HMPREF9182_RS06055 HMPREF9182_RS06530 purine-nucleoside tRNA charging triose-phosphate acyl-carrier protein a 3-oxoglutaryl- acyl-carrier protein oxooctadec- [acp] [acp] 5-enoyl-[acp] [acp] dUDP 5-phospho-β- adenylo-succinate gln C1 Compound Utilization α-D-glucopyranose glutaminyl-tRNA hexanoyl-[acyl-carrier- HMPREF9182_RS03665 phosphate kinase: [acp] methyl ester maltotetraose D-ribose 1- a purine base gln UTP CDP D-ribosylamine phosphorylase: isomerase: and Assimilation 6-enoyl-[acp] 1-phosphate biosynthesis via protein] reductase: 3-oxoacyl-ACP reductase: HMPREF9182_RS08745 phosphate RS09530 adenylosuccinate lyase: HMPREF9182_RS02190 beta-ketoacyl-[acyl-carrier- HMPREF9182_RS02485D-glyceraldehyde L-rhamnulofuranose RS07420 CDP reductase: phosphoribosylamine- arg transamidation HMPREF9182_RS03665 D-tagatofuranose HMPREF9182_RS05475 adenine protein] synthase II: HMPREF9182_RS08895 DHAP formate assimilation into 5,10- -glycine ligase: arginine--tRNA ligase: 3-phosphate rhamnulokinase: 1,6-bisphosphate dUTP HMPREF9182_RS08570 HMPREF9182_RS03660 methylenetetrahydrofolate HMPREF9182_RS05510 HMPREF9182_RS05425 an L-arginyl- glu a (3R)-3- glyceraldehyde-3- UDP-N-acetyl-α-D-muramoyl- a [protein] N-terminal- N-acetyl-β-D-glucosamine- a 3- a (6Z)-3- adenine a hexanoyl-[acp] a 2,3,4-saturated HMPREF9182_RS01070 tagatose-bisphosphate an acyl-[acyl- quinoxaline-2- maltopentaose a 3-oxooctadecanoyl- a cis-delta17-3- a nucleoside DHAP dCDP [tRNA Arg ] hydroxyacyl-[acyl- phosphate dehydrogenase: L-alanyl-γ-D-glutamyl- D-alanyl-D-alanine a malonyl-[acp] aryl-carrier protein formyl-L-methionine 1,6-anhydro-N- oxodocosanoyl- oxooctadec- L-homoserine deoxyuridine CTP AMP fatty acyl-[acp] L-rhamnulose aldolase: formate carrier protein] carboxyl adenylate a tRNA precursor CTP ATP ATP H O [acp] oxo-C36:1-[acp] triphosphate ITP GAR phosphoribosyltransferase: a tRNA Arg carrier protein] meso-2,6-diaminopimelate glycogen/starch/alpha- peptide deformylase: acetyl-β-D-muramate 2 [acp] 6-enoyl-[acp] NAD(P)H-dependent RS09525 RS02380 5'-triphosphate 3-oxoacyl-[acyl-carrier- HMPREF9182_RS07095 formate-- UDP-N-acetylmuramoyl- beta-ketoacyl-[acyl-carrier- acyl carrier protein: beta-N- ATPase: 3-oxoacyl-ACP reductase: 3-oxoacyl-ACP reductase: 3-oxoacyl-ACP reductase: 3-oxoacyl-ACP reductase: nucleoside-triphosphate HMPREF9182_RS01175 3-hydroxyacyl- 1-phosphate HMPREF9182_RS06115 glucan phosphorylase: CCA tRNA HMPREF9182_RS04405 homoserine O- glycerol-3-phosphate nucleotidohydrolase: an L-glutamyl- protein] reductase: tripeptide--D-alanyl- protein] synthase II: HMPREF9182_RS03680 acetylhexosaminidase: HMPREF9182_RS08895 HMPREF9182_RS08895 HMPREF9182_RS08895 HMPREF9182_RS08895 nucleoside-triphosphate phosphoribosylglycinamide phosphoribosylglycinamide Gln [acp] dehydratase: tetrahydrofolate ligase: HMPREF9182_RS08615 HMPREF9182_RS03260 diphosphatase: succinyltransferase: adenylate kinase: [tRNA ] rhamnulose-1- chitobiose degradation tagatose-bisphosphate D- alanine ligase: HMPREF9182_RS03660 nucleotidyltransferase: peptide deformylase: dehydrogenase: diphosphatase: HMPREF9182_RS06960 formyltransferase: formyltransferase: HMPREF9182_RS03665 HMPREF9182_RS03650 13-DPG HMPREF9182_RS00140 acyl carrier protein: HMPREF9182_RS04455 3-oxoacyl-[acyl-carrier- 3-oxoacyl-[acyl-carrier- 3-oxoacyl-[acyl-carrier- 3-oxoacyl-[acyl-carrier- HMPREF9182_RS03590 HMPREF9182_RS06300 AMP phosphate aldolase: aldolase: an N 10 - glycogen/starch/ a tRNA HMPREF9182_RS00745 HMPREF9182_RS07610 [+ 2 isozymes] HMPREF9182_RS01170 HMPREF9182_RS06935 nucleoside-triphosphate CDP dCTP dCMP HMPREF9182_RS05495 HMPREF9182_RS06065 glutamyl-tRNA beta-ketoacyl-[acyl-carrier- UDP-N-acetyl-α-D-muramoyl-L-HMPREF9182_RS09130 3-oxoacyl-[acyl-carrier- HMPREF9182_RS06040 protein] reductase: protein] reductase: protein] reductase: protein] reductase: HMPREF9182_RS03590 nitrite nitrite HMPREF9182_RS01060 N,N'- HMPREF9182_RS08750 containing a an N-terminal L- beta-N- H + phosphate ADP a nucleoside 5'- sn-glycerol RS00695 phosphoglycerate kinase: formyltetrahydrofolate γ a quinoxaline-2- alpha-glucan family formate HMPREF9182_RS03665 HMPREF9182_RS03665 HMPREF9182_RS03665 HMPREF9182_RS03665 O-succinyl-L- formate formate diphosphatase: CDP reductase: deoxycytidylate deaminase: amidotransferase: protein] synthase II: diacetylchitobiose alanyl- -D-glutamyl-meso-2,6- protein] reductase: 3' CCA end methionyl-[protein] acetylhexosaminidase: a (3R)-3- a (3R)-3- a (3R,6Z)-3- a cis-delta17-3- monophosphate RS05435 FGAR cys HMPREF9182_RS07140 D-glyceraldehyde bifunctional AMP carboxyl-[aryl- phosphorylase: homoserine 3-phosphate IMP HMPREF9182_RS03590 HMPREF9182_RS08570 HMPREF9182_RS01265 ADP pyrimidine ribonucleosides salvage I cysteine--tRNA ligase: HMPREF9182_RS09995 HMPREF9182_RS03660 (S)-lactaldehyde DHAP 6'-phosphate DHAP diaminopimeloyl-D-alanyl-D-alanine HMPREF9182_RS03665 HMPREF9182_RS06465 hydroxyoctadecanoyl- hydroxydocosanoyl- hydroxyoctadec- hydroxyC36:1- 3-phosphate methylenetetrahydrofolate carrier protein] HMPREF9182_RS06680 1,6-anhydro-N- HMPREF9182_RS07680 an L-cysteinyl- Asp-tRNA(Asn) acyl-carrier protein a 3-oxoacyl-[acp] GlcNAc [acp] [acp] 6-enoyl-[acp] [acp] dUMP dCDP dUMP phosphoribosylformylglycinamidine a 3-oxooctanoyl- 3-phospho-D-glycerate α-D-glucopyranose β cytidine Cys N-monoacetylchitobiose dehydrogenase/ maltotetraose acetyl- -muramate RS08930 [tRNA ] /Glu-tRNA(Gln) [acp] 1-phosphate thymidylate synthase: thymidylate synthase: synthase: HMPREF9182_RS06050 CMP phosphorylation Cys 6'-phosphate methenyltetrahydrofolate a tRNA amidotransferase a trans-2- RS06845 HMPREF9182_RS00725 HMPREF9182_RS00725 3-oxoacyl-ACP reductase: 2,3,4-saturated-fatty- phosphoglycerate mutase: 6-phospho-beta- cyclohydrolase: cytidine deaminase: subunit GatA: gatA a 2,3,4-saturated enoyl-[acyl- FGAM CMP HMPREF9182_RS08895 acid-[acp] reductase: HMPREF9182_RS02930 trehalose degradation I (low osmolarity) HMPREF9182_RS03020 dTMP dCTP dTMP HMPREF9182_RS00865 fatty acyl-[acp] glucosidase: D-mannose degradation a [formate C 2-amino-6-[1-hydroxyethyl]- (R)-4'- salicin 6- a 3,5,7,9,11,13,15- an (11Z)-3- a (5Z)-3- a uracil 1498 sn-glycerol (d)CMP kinase: an L-glutaminyl- HMPREF9182_RS03665 carrier protein] a reduced maltoheptaose a [ThiI sulfur-carrier a 3-oxoicosanoyl- (R)-mevalonate CMP 3-oxoacyl-[acyl-carrier- HMPREF9182_RS08495 a 5,10- SAM acetyltransferase]- a palmitoleoyl-[acp] a malonyl-[acp] phosphopantothenoyl- cys phosphate hepta-oxo- oxooctadec- oxododec- ser phosphoribosylformylglycinamidine HMPREF9182_RS01100 [tRNA Gln ] 2-phospho-D-glycerate α,α-trehalose flavodoxin 7-methyl-7,8-dihydropterin protein]-L-cysteine GTP H O [acp] diphosphate in 16S rRNA 3-phosphate RS05950 dTMP kinase: dTMP kinase: uridine protein] reductase: D-mannopyranose methenyltetrahydrofolate glycine 2-amino-4-hydroxy-6- glycogen/starch/alpha- L-cysteine 6-phospho-beta- 2 hexadecanoyl-[PKS-acp] 11-enoyl-[acp] 5-enoyl-[acp] cyclo-ligase: HMPREF9182_RS06060 CDP 6-phospho-beta- pyruvate formate lyase- 3-oxoacyl-[acyl-carrier- cysteine desulfurase: aldo/keto reductase: 3-oxoacyl-ACP reductase: 3-oxoacyl-ACP reductase: 3-oxoacyl-[acyl-carrier- diphosphomevalonate 16S rRNA (uracil(1498)- glycerol-3-phosphate 1- L-serine ammonia- RS04300 HMPREF9182_RS08670 HMPREF9182_RS08670 gln HMPREF9182_RS03665 6-phosphate 6-phosphate hydroxymethyldihydropteridine glucan phosphorylase: phosphopantothenoylcysteine glucosidase: GTPase Era: uridine kinase: 2,3,4-saturated fatty enolase: glucosidase: mannose-6-phosphate bifunctional activating protein: protein] reductase: HMPREF9182_RS00075 HMPREF9182_RS03965 HMPREF9182_RS08895 HMPREF9182_RS08895 protein] reductase: decarboxylase: N(3))-methyltransferase: O-acyltransferase PlsY: lyase, iron-sulfur- a (3R)-3- diphosphokinase: HMPREF9182_RS08615 decarboxylase: HMPREF9182_RS08495 HMPREF9182_RS02895 dTDP dTDP AIR HMPREF9182_RS01350 acyl-[acp]:NAD+ HMPREF9182_RS09215 HMPREF9182_RS09510 isomerase, class I: methylenetetrahydrofolate HMPREF9182_RS03475a [formate C HMPREF9182_RS03665 a [ThiI sulfur- [+ 2 isozymes] aldo/keto reductase: 3-oxoacyl-[acyl-carrier- 3-oxoacyl-[acyl-carrier- HMPREF9182_RS03665 HMPREF9182_RS04595 HMPREF9182_RS02145 dependent, subunit beta: an L-glutaminyl- alpha,alpha- HMPREF9182_RS00130 [+ 3 isozymes] HMPREF9182_RS07295 3 hydroxyoctanoyl- N-acetyl-D- a flavodoxin HMPREF9182_RS04985 glycogen/starch/ 6-phospho-beta- an N - 1-oleoyl-sn Metabolic Regulator [tRNA Gln ] : HMPREF9182_RS04385 dehydrogenase/ met 5'-deoxyadenosine acetyltransferase]- beta-ketoacyl-[acyl-carrier- [1-(2-amino-7-methyl-4-oxo- carrier protein]-S- ala 9-hydroxy-3,5,7,11,13,15-HMPREF9182_RS04510 protein] reductase: protein] reductase: 3-oxoacyl-ACP reductase: HMPREF9182_RS05970 UMP [acp] phosphotrehalase: semiquinone alpha-glucan family phosphate GDP H + methyluracil 1498 RS09950 CTP Biosynthesis Gln phosphoenolpyruvate glucosamine D-glucosamine F6P methenyltetrahydrofolate protein] synthase II: 7,8-dihydro-3H-pteridin- 4'-phosphopantetheine glucosidase: HMPREF9182_RS03665 HMPREF9182_RS03665 HMPREF9182_RS08895 IPP -glycerol 3- a tRNA (3R)-3-hydroxyoctanoyl- HMPREF9182_RS03665 HMPREF9182_RS03480 glycin -2-yl radical sulfanyl-L-cysteine hexaoxohexadecanoyl- a (3R)-3- a (3R,11Z)-3- a (3R,5Z)-3- pyruvate RS05935 6-phosphate phosphorylase: HMPREF9182_RS09510 in 16S rRNA phosphate cyclohydrolase: HMPREF9182_RS03660an (11Z)-3- 6-yl)]ethyl diphosphate [PKS-acp] hydroxyicosanoyl- hydroxyoctadec- hydroxydodec- dTTP dTTP ppGpp biosynthesis [acyl-carrier protein] pyruvate kinase: HMPREF9182_RS06680 β-D-glucose HMPREF9182_RS03020 acyl-carrier protein oxooctadec- salicyl alcohol [acp] 11-enoyl-[acp] 5-enoyl-[acp] dehydratase: HMPREF9182_RS03170 glucokinase: α-D-glucopyranose 6-phosphate a 5,10- 11-enoyl-[acp] maltohexaose HMPREF9182_RS03650 HMPREF9182_RS00730 1-phosphate RS04100 pppGpp D-glucopyranose methylenetetrahydrofolate Amino Acid Biosynthesis pyruvate D-glucopyranose fructose degradation RS00720 bifunctional (p)ppGpp glu a (2E)-oct- gondoate biosynthesis (anaerobic) 6-phosphate synthetase/guanosine- 2-enoyl-[acp] 4 β-D-fructofuranose an O - D-cellobiose arbutin-6- DNA with adenine:7,8- a (9Z)-3- a double 3',5'-bis(diphosphate) 3'- an L-glutamyl- 1-stearoyl-sn- seleno-L- a [protein]- DNA combined with exogenous DNA an acyl-[acyl- sn-glycerol a dipetide with an N- a 3-oxopimeloyl- a cis-delta19-3- a [protein]- riboflavin L-cysteine biosynthesis glycine biosynthesis I octanoyl-[acyl-carrier- 1-phosphate a palmitoyl-[acp] methylthymine 6'-phosphate phosphate dihydro-8- oxooctacos- stranded DNA phe superpathway of L- L-alanine biosynthesis I L-cysteine biosynthesis I Glu glycerol 3-phosphate homocysteine L-cysteine to form a recombinational junction carrier protein] 3-phosphate terminal L-aspartate [acp] methyl ester oxo-C38:1-[acp] L-histidine VI (from L-methionine) L-proline biosynthesis I pyrophosphohydrolase: [tRNA ] protein] reductase: a malonyl-[acp] an oleoyl-[acp] 1-phosphofructokinase: in DNA 6-phospho-beta- 6-phospho-beta- oxoguanine mismatch dipeptidase: 9-enoyl-[acp] DNA gyrase subunit B: threonine biosynthesis guanosine 3'-diphosphate glu 1-acyl-sn-glycerol-3- methylated-DNA-- Holliday junction glycerol-3-phosphate 1- A/G-specific adenine 3-oxoacyl-ACP reductase: 3-oxoacyl-ACP reductase: 3-oxoacyl-ACP reductase: bifunctional riboflavin RS04335 HMPREF9182_RS04590 a tRNA beta-ketoacyl-[acyl-carrier- Macromolecule Modification melibiose degradation HMPREF9182_RS00765 5-methyltetrahydropteroyltriglutamate- glucosidase: glucosidase: HMPREF9182_RS09190 aspartate histidine kinase: RS01540 3-methyl-2- HMPREF9182_RS03665 β-D-fructose 1,6- phosphate acyltransferase: resolvase RuvX: O-acyltransferase PlsY: glycosylase: HMPREF9182_RS07380 HMPREF9182_RS08895 HMPREF9182_RS08895 HMPREF9182_RS08895 kinase/FAD synthetase: 5'-triphosphate 3'- protein] synthase II: - homocysteine S-methyltransferase: [protein]-cysteine S- aminotransferase: HMPREF9182_RS02770 met ser GTP pyrophosphokinase: HMPREF9182_RS08495 HMPREF9182_RS08495 HMPREF9182_RS00110 dipeptidase PepV: DNA gyrase subunit A: oxaloacetate glu oxobutanoatebranched-chain amino ser diphosphatase: an (11Z)-3- bisphosphate HMPREF9182_RS03255 methyltransferase: HMPREF9182_RS05315 HMPREF9182_RS02145a 1-acyl-sn 3-oxoacyl-[acyl-carrier- 3-oxoacyl-[acyl-carrier- 3-oxoacyl-[acyl-carrier- HMPREF9182_RS00995 methionine HMPREF9182_RS00090 an octanoyl-[acp] HMPREF9182_RS03660 queuosine biosynthesis melibiose 1-stearoyl-2-palmitoyl- HMPREF9182_RS07580 6-phospho-beta- 6-phospho-beta- HMPREF9182_RS01690 HMPREF9182_RS00040 HMPREF9182_RS04625 a [protein]- aspartate serine acid aminotransferase: serine O-acetyltransferase: HMPREF9182_RS04590 oxo-icos-11- acyl-carrier protein HMPREF9182_RS02815 resolution of recombinational junction acyl-carrier protein -glycerol 3- an apurinic site protein] reductase: protein] reductase: protein] reductase: keto- adenosyltransferase: glutamate 5-kinase: alpha-galactosidase: sn-glycerol 3-phosphate a [protein]-S- glucosidase: glucosidase: adenine a proteinogenic a negatively N-phospho- FMN aminotransferase: hydroxymethyltransferase: glyA SeMet a thymine in DNA formation of two intact strands phosphate within DNA asp HMPREF9182_RS03665 HMPREF9182_RS03665 HMPREF9182_RS03665 HMPREF9182_RS00815 HMPREF9182_RS02125 HMPREF9182_RS07660 3-oxoacyl-[acyl-carrier- enoyl-[acp] HMPREF9182_RS05410 a (3R)-3- a cis-delta19-3- a cis-delta9-3- supercoiled DNA phenylpyruvate RS02645 HMPREF9182_RS01260 HMPREF9182_RS04625 γ-L-glutamyl ile preQ methyl-L-cysteine HMPREF9182_RS09510 HMPREF9182_RS09510 amino acid L-histidine RS05255 gly 3-oxoacyl-[acyl-carrier- 0 hydroxypimeloyl- hydroxyC38:1- hydroxyC28:1- SAM val O-acetyl-L-serine isoleucine--tRNA ligase: protein] reductase: D-galactopyranose D-glucopyranose Amine and Polyamine Degradation D-glucopyranose β-D-glucose 5-phosphate protein] reductase: D-glucopyranose hydroquinone asp HMPREF9182_RS03060 HMPREF9182_RS03665 6-phosphate 6-phosphate [acp] methyl ester [acp] [acp] glutamate-5-semialdehyde an L-isoleucyl- HMPREF9182_RS03665 cysteine synthase A: GTP ppGpp [tRNA Ile ] beta-ketoacyl-[acyl-carrier- superpathway of N-acetylglucosamine, aspartate kinase: dehydrogenase: Ile 3-oxoacyl-ACP reductase: preQ HMPREF9182_RS03750 a tRNA protein] synthase II: 1 N-acetylmannosamine and N- 6 RS04065 RS04435 HMPREF9182_RS03700 HMPREF9182_RS00810 HMPREF9182_RS08895 an O - an [apo BCAA (5Z,8Z,11Z,14Z,17Z)-3- phosphoenol an [HPr]- 5-(2-hydroxyethyl) guanosine 2251 a guanine 527 a supercoiled (2Z,4E)-2- a [protein]- HMPREF9182_RS03660 Nucleoside and Nucleotide Degradation 1-stearoyl-sn- pyruvate a [protein]- a sulfurated 1-cis-vaccenoyl-sn- a 3-oxoglutaryl- NAD + a (3R,11Z)-3- tRNA guanosine(34) acetylneuraminate degradation a stearoyl-[acp] methylguanine 4-methyl-2- dehydrogenase hydrogen cyanide oxodocosapentaenoyl-CoA pyruvate L-histidine -4-methylthiazole in 23S rRNA in 16S rRNA duplex DNA hydroxyhexa- L-tyrosine L-glutamate-5- S-adenosyl-L-methionine cycle I cys glycerol 3-phosphate L-cysteine [sulfur carrier] glycerol-3-phosphate [acp] methyl ester SAH L-aspartyl- ala a 3-oxodecanoyl- hydroxy-icos- transglycosylase Tgt: N-acetylneuraminate pyruvate, in DNA oxopentanoate E2 protein] N 6 phosphoenolpyruvate- 4-methyl-5(B-hydroxyethyl) 23S rRNA 16S rRNA helicase: 2,4-dienedioate semialdehyde 1-acyl-sn-glycerol-3- methylated-DNA-- rhodanese domain- 3-oxoacyl-[acyl-carrier- 1-acyl-sn-glycerol-3- 3-oxoacyl-ACP reductase: 4-oxalocrotonate [acp] HMPREF9182_RS06885 superpathway of purine deoxyribonucleosides degradation phosphate dikinase: branched-chain alpha- -protein -thiazole monophosphate (guanosine(2251)-2'-O)- HMPREF9182_RS03740 tyrosine protein kinase: NAD kinase: 4-phosphate 11-enoyl-[acp] N-acetylneuraminate lyase: phosphate acyltransferase: [protein]-cysteine S- -lipoyl-L-lysine containing protein: protein] reductase: HMPREF9182_RS08895 (guanine(527)-N(7))- 5'-methylthioadenosine/ L-alanine biosynthesis III (3R,11Z)-3-hydroxy-icos-11- a 7-aminomethyl-7- keto acid dehydrogenase phosphate acyltransferase: tautomerase: HMPREF9182_RS05225 HMPREF9182_RS00095 SAM alanine racemase: GTP pyrophosphokinase: 3-oxoacyl-ACP reductase: HMPREF9182_RS06775 HMPREF9182_RS03255 HMPREF9182_RS01800 HMPREF9182_RS08175 HMPREF9182_RS03665 phosphotransferase: biosynthesis protein: methyltransferase RlmB: methyltransferase RsmG: replicative DNA helicase: RS08860 RS00495 aspartate-semialdehyde leu deazaguanosine 34 N-acetyl-D- methyltransferase: HMPREF9182_RS03255 3-oxoacyl-[acyl-carrier- HMPREF9182_RS00540 adenosylhomocysteine HMPREF9182_RS07975 HMPREF9182_RS00090 bifunctional (p)ppGpp leucine--tRNA ligase: enoyl-[acp] dehydratase: 1-stearoyl-2-stearoyl-sn subunit E2: an unsulfurated HMPREF9182_RS08590 HMPREF9182_RS07910 HMPREF9182_RS07710 HMPREF9182_RS08225 HMPREF9182_RS06015 a [protein]- HMPREF9182_RS08895 acyl-carrier protein phosphoenol HMPREF9182_RS02815 a [apo BCAA dehydrogenase thiocyanate (3R,5Z,8Z,11Z,14Z,17Z)-3- an [HPr protein]- 1-cis-vaccenoyl- 4-methyl-5-(2- protein] reductase: 2-O- an N 7 - nucleosidase: dehydrogenase: synthetase/guanosine- HMPREF9182_RS03650 in tRNA 2'-deoxyguanosine mannosamine diphosphate AMP H + HMPREF9182_RS00665 a single (3E)-2-oxohex- NADP + HMPREF9182_RS04495 an L-leucyl- -glycerol 3-phosphate a [protein]-S- 6 [sulfur carrier] π 2-palmitoleoyl-sn- 2251 527 L-tyrosine (S)-1-pyrroline- cys 3-oxoacyl-[acyl-carrier- pyruvate a guanine in DNA E2 protein] N -S-[3- hydroxydocosapentaenoyl-CoA N -phospho- pyruvate phosphooxyethyl) HMPREF9182_RS03665 methylguanosine methylguanine HMPREF9182_RS08935 HMPREF9182_RS00170 methionine 3',5'-bis(diphosphate) 3'- Leu tRNA preQ1(34) S- N-acetylmannosamine a (3R)-3- stranded DNA 3-enedioate D-ala [tRNA ] a (2E,11Z)-icosa- 2'-deoxyadenosine methyl-L-cysteine glycerol-3-phosphate phosphate 5-carboxylate cysteine desulfurase: Leu protein] reductase: methylbutanoyl]dihydrolipoyl- L-histidine thiazole hydroxyglutaryl- in 23S rRNA in 16S rRNA S-ribosyl-L- L-aspartate- adenosyltransferase: pyrophosphohydrolase: a tRNA adenosylmethionine kinase: HMPREF9182_RS04235 HMPREF9182_RS03665 2,11-dienoyl-[acp] L-lysine [acp] methyl ester RS03810 RS01295 homocysteine semialdehyde pyrroline-5- HMPREF9182_RS01260 HMPREF9182_RS04590 ribosyltransferase- HMPREF9182_RS06780 carboxylate reductase: L-asparagine biosynthesis [+ 2 isozymes] a (3R)-3- (2E,11Z)-icosa-2,11- isomerase QueA: purine-nucleoside N-acetyl-D- S-ribosylhomocysteine homoserine HMPREF9182_RS00805 met SAH III (tRNA-dependent) ala GDP hydroxydecanoyl- dienoyl-[acp] reductase: HMPREF9182_RS08470 phosphorylase: mannosamine 1-stearoyl- a 1-acyl-sn a reduced 1518 966 lyase: dehydrogenase: [acp] HMPREF9182_RS02195 an [apo BCAA a ribonucleoside adenine / 1-myristoyl-sn- a [protein]- a (7Z)-3-oxo- a guanine dTTP HMPREF9182_RS03665 34 6-phosphate 1-cis-vaccenoyl-sn- an acyl-[acyl- + + FAD DNA with lesion pyridoxamine 5'-methylthioadenosine/ 3-hydroxydecanoyl- an epoxyqueuosine a palmitoleoyl-[acp] an oleoyl-[acp] sn-glycerol -glycerol 3- (S)-3-methyl-2- dehydrogenase ferredoxin [iron- NADP H formate adenine 1519 in 16S rRNA L-threonine hexadec-7- a malonyl-[acp] in 16S rRNA leu Peptide RS02835 Peptide HMPREF9182_RS03815 HMPREF9182_RS02250 pro purine-nucleoside putative N- glycerol-3-phosphate carrier protein] triphosphate glycerol 3-phosphate nucleoside-triphosphate val in tRNA 3-phosphate phosphate oxopentanoate 6 sulfur] cluster 16S rRNA (adenine(1518)- FAD:protein FMN 16S rRNA excinuclease RS05575 adenosylhomocysteine asp valine--tRNA ligase: [acp] dehydrase: a gondoyl-[acp] 1-acyl-sn-glycerol-3- 1-acyl-sn-glycerol-3- 1-acyl-sn-glycerol-3- E2 protein] N ferredoxin--NADP(+) anaerobic ribonucleoside- 1-acyl-sn-glycerol-3- enoyl-[acp]3-oxoacyl-[acyl-carrier- diphosphatase: Asn phosphorylase: acetylmannosamine-6- branched-chain alpha- beta-ketoacyl-[acyl-carrier- branched-chain amino pyridoxamine kinase: L-homoserine nucleosidase: aspartyl-tRNA purine-nucleoside 2'-deoxyinosine phosphate acyltransferase: phosphate acyltransferase: -lipoyl-L-lysine reductase: triphosphate reductase: N(6)/adenine(1519)-N(6))- transferase: protein] reductase: (guanine(966)-N(2))- ABC subunit UvrA: L-homocysteine 5-methyltetrahydropteroyltriglutamate- HMPREF9182_RS04150 an L-valyl- HMPREF9182_RS03650 HMPREF9182_RS02190 phosphate 2-epimerase: phosphate acyltransferase: phosphate acyltransferase: HMPREF9182_RS03590 HMPREF9182_RS08935 synthetase: phosphorylase: keto acid dehydrogenase HMPREF9182_RS05285 dimethyltransferase RsmA: HMPREF9182_RS00350 protein] synthase II: methyltransferase RsmD: HMPREF9182_RS04815 acid aminotransferase: HMPREF9182_RS01285 Peptide RS05530 Peptide - homocysteine S-methyltransferase: [tRNA Val ] 1-cis-vaccenoyl-HMPREF9182_RS03255 HMPREF9182_RS032551-stearoyl-2- HMPREF9182_RS03255a 1,2-diacyl- an oxidizedHMPREF9182_RS01885 HMPREF9182_RS03255 HMPREF9182_RS03665 HMPREF9182_RS08015 L-glutamate biosynthesis III a (2E)-dec- HMPREF9182_RS02195 HMPREF9182_RS06745 subunit E2: a 2'-deoxyribonucleoside HMPREF9182_RS07035 HMPREF9182_RS03660 HMPREF9182_RS04125 [+ 2 isozymes] HMPREF9182_RS02125 dTMP 2+ 2+ homoserine kinase: an L-aspartyl- Val 6 1518 1-myristoyl-2- a [protein]-FMN- 2 Zn RS05100 Zn HMPREF9182_RS07580 a tRNA 2-enoyl-[acp] a queuosine 34 N-acetyl-D- acyl-carrier protein 2-palmitoleoyl-sn- acyl-carrier protein oleoyl-sn-glycerol acyl-carrier protein sn-glycerol an [apo BCAA dehydrogenase NADPH ferredoxin [iron- N -dimethyladenine 3-oxoacyl-ACP reductase: a 3- an N - DNA without 4-methyl-2- pyridoxamine L-homocysteine S-ribosyl-L-homocysteine Asn purine-nucleoside HMPREF9182_RS00665 5'-triphosphate AMP HMPREF9182_RS02245 [tRNA ] biotin-carboxyl carrier protein assembly purine-nucleoside glucosamine glycerol-3-phosphate 3-phosphate 3-phosphate E2 protein] N 6 -S-[2- sulfur] cluster /N 6 -dimethyladenine 1519 palmitoleoyl-sn- L-threonine HMPREF9182_RS08895 oxodocosanoyl- methylguanine 966 5'-phosphate a cation RS02085 a cation decanoyl-[acyl-carrier- in tRNA a (3R,7Z)-3- lesion oxopentanoate 2-oxoglutarate phosphorylase: phosphorylase: 6-phosphate methylbutanoyl]dihydrolipoyl- in 16S rRNA glycerol 3-phosphate [acp] in 16S rRNA a purine RS00535 a purine Asp-tRNA(Asn) NADP-specific glutamate protein] reductase: Carboxylate Degradation hydroxy-hexadec- O-phospho- a [biotin carboxyl- HMPREF9182_RS02190 HMPREF9182_RS02195 N-acetylglucosamine-6- L-lysine L-cystathionine /Glu-tRNA(Gln) dehydrogenase: HMPREF9182_RS03665 7-enoyl-[acp] a cation RS06560 a cation L-homoserine carrier protein]-L-lysine purine-nucleoside phosphate deacetylase: + + amidotransferase HMPREF9182_RS07450 Na RS03980 Na S-ribosylhomocysteine lyase: ala bifunctional biotin-- phosphorylase: HMPREF9182_RS03975 pyruvate fermentation to acetate IV subunit GatA: gatA alanine--tRNA ligase: a decanoyl-[acp] lipoprotein posttranslational HMPREF9182_RS03815 glu 1-stearoyl- a 2-acetyl-1-alkyl- a 2'- 1-myristoyl- a cytidine 1402 UTP [acetyl-CoA-carboxylase] HMPREF9182_RS02190 D-glucosamine 1-myristoyl-sn- an acyl-[acyl- a (7Z)-hexadec- sn-glycerol 1-palmitoyl-sn- (R)-mevalonate a cation RS07625 a cation an L-asparaginyl- HMPREF9182_RS08555 an L-alanyl- modification a palmitoleoyl-[acp] sn-glycerol a malonyl-[acp] sn-glycero-3- a stearoyl-[acp] H O diphosphate deoxyribonucleoside [DNA] sn-glycerol 3-phosphate a protein sn-glycerol ile asp fluoride RS09345 fluoride synthetase/biotin pyruvate 2 glycerol 3-phosphate in 16S rRNA nucleoside-triphosphate Asn Ala 3-oxoacyl-[acyl-carrier- 6-phosphate glycerol 3-phosphate carrier protein] 7-enoyl-[acp] 3-phosphate [tRNA ] [tRNA ] a [prolipoprotein]- 2-deoxy-α-D- 1-acyl-sn-glycerol-3- 3-phosphate1-acyl-sn-glycerol-3- beta-ketoacyl-[acyl-carrier- phosphocholine glycerol-3-phosphate 1- manganese-dependent 5'-triphosphate DNA polymerase III: 3-phosphate 16S rRNA Ala operon repressor: 1-alkyl-2- 1-acyl-sn-glycerol-3- glycerol-3-phosphate 1- ATP-dependent diphosphatase: cys thr a tRNA protein] reductase: 1-acyl-sn-glycerol-3- mevalonate kinase: branched-chain amino aspartate Mg 2+ RS04820 Mg 2+ HMPREF9182_RS01450 L-cysteine ribose 1-phosphate phosphate acyltransferase: phosphate acyltransferase: protein] synthase II: acetylglycerophosphocholine O-acyltransferase PlsY: inorganic pyrophosphatase: HMPREF9182_RS03180 phosphate acyltransferase: Clp protease (cytosine(1402)-N(4))- HMPREF9182_RS03590 nitrate RS05610 nitrate HMPREF9182_RS03665 formate C- O-acyltransferase PlsY: phosphate acyltransferase: HMPREF9182_RS07290 acid aminotransferase: aminotransferase: 1-myristoyl-2-HMPREF9182_RS03255 aHMPREF9182_RS03255 1-stearoyl 2- HMPREF9182_RS03660a (9Z)-3-oxo- : HMPREF9182_RS021451-stearoyl- HMPREF9182_RS03465 HMPREF9182_RS03235 HMPREF9182_RS03255 proteolytic subunit: methyltransferase RsmH: a [biotin carboxyl-carrier prolipoprotein acetyltransferase: HMPREF9182_RS02145 HMPREF9182_RS03255 HMPREF9182_RS02125 HMPREF9182_RS04625 UMP beta-ketoacyl-[acyl-carrier- α-D-glucosamine + 1-palmitoyl-2- 4 HMPREF9182_RS03910 2+ 2+ 6 palmitoleoyl-sn- acyl-sn-glycerol acyl-carrier protein octadec-9- HMPREF9182_RS07490 sn-glycerol phosphate H HMPREF9182_RS03370 1,2-dimyristoyl- an N - RS03295 Mg protein]-N -biotinyl-L-lysine diacylglyceryl transferase: HMPREF9182_RS07330 acyl-carrier protein acyl-carrier protein a 1-alkyl-2-lyso- acyl-carrier protein [+ 5 isozymes] 1-(18-hydroxyoleoyl)- (R)-mevalonate (S)-3-methyl-2- Mg protein] synthase II: palmitoleoyl-sn- 1402 oxaloacetate predicted HMPREF9182_RS02795 6-phosphate glycerol 3-phosphate 3-phosphate enoyl-[acp] sn-glycero-3- acetate 3-phosphate [DNA] a peptide sn-glycerol methylcytidine 5-phosphate HMPREF9182_RS03660 2-deoxy-D-ribose sn-glycrol 3-phosphate a peptide oxopentanoate ABC glucosamine-6- glycerol 3-phosphate 3-phosphate in 16S rRNA a sugar a sugar asn a 3- a [prolipoprotein]-S- 5-phosphate phosphocholine transporter asparagine--tRNA ligase: diacylglyceryl-L-cysteine phosphate deaminase: acetyl-CoA formate oxododecanoyl- a [biotin carboxyl- RS00325 of a sugar HMPREF9182_RS01920 an L-asparaginyl- HMPREF9182_RS08475 [acp] deoxyribose- a DNA containing 34 a 1-alkyl-sn 1-palmitoyl- Asn carrier-protein dimer]- phosphate 1-myristoyl- a single- a guanine (indol-3-yl) uridine [tRNA ] signal peptidase II: 1-palmitoyl-sn- a (3Z)-dec- a [protein]- sn-glycerol 1-(18-hydroxyoleoyl)- (R)-mevalonate sn-glycerol roseoflavin a D-hexose RS00125 3-oxoacyl-ACP reductase: 6 phosphate aldolase: purine ribonucleosides degradation F6P a palmitoleoyl-[acp] a myristoyl-[acp] sn-glycerol a malonyl-[acp] S methyl a palmitoyl-[acp] queuine -glycerol 3- sn-glycerol , Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis Asn N -biotinyl-L-lysine acetyltransferase: p stranded RNA sn-glycrol 3-phosphate in tRNA 3-phosphate acetamide tRNA HMPREF9182_RS08895 HMPREF9182_RS00825 glycerol 3-phosphate 3-enoyl-[acp] L-cysteine 3-phosphate 5-phosphate HMPREF9182_RS00870 HMPREF9182_RS00105 3-phosphate beta-ketoacyl-[acyl-carrier- phosphotriester methylated-DNA-- glycerol-3-phosphate 1- polyribonucleotide tRNA guanosine(34) phosphate 3-phosphate bifunctional riboflavin uridine kinase: acetyl-CoA 1-acyl-sn-glycerol-3- 1-acyl-sn-glycerol-3- 1-acyl-sn-glycerol-3- 1-acyl-sn-glycerol-3- 1-acyl-sn-glycerol-3- glycerol-3-phosphate 1- glucokinase: 3-oxoacyl-[acyl-carrier- acetyl-CoA carboxylase [protein]-cysteine S- nucleotidyltransferase: transglycosylase Tgt: phosphomevalonate kinase: amidase: kinase/FAD synthetase: HMPREF9182_RS01350 [2Fe-2S] iron-sulfur cluster biosynthesis carboxylase carboxyl: an (S-diacyl-sn- phosphate acyltransferase: phosphate acyltransferase: protein] synthase II: O-acyltransferase PlsY: phosphate acyltransferase: O-acyltransferase PlsY: HMPREF9182_RS00730 RS08850 10 biotin carboxylase subunit: a lipoprotein adenosine HMPREF9182_RS07655 HMPREF9182_RS06885 phosphate acyltransferase: phosphate acyltransferase: HMPREF9182_RS01190 N -formyl-tetrahydrofolate biosynthesis heme b biosynthesis thioredoxin pathway lipoate biosynthesis protein] reductase: HMPREF9182_RS03635 glyceryl)-L-cysteinyl- D-glyceraldehyde acetyl phosphate HMPREF9182_RS03255 HMPREF9182_RS03255 HMPREF9182_RS03660 methyltransferase: HMPREF9182_RS02145 HMPREF9182_RS07300 HMPREF9182_RS00995 HMPREF9182_RS03645 signal peptide acetaldehyde 1-palmitoyl-2- 1,2-dimyristoyl- a (5Z)-3- 1-palmitoyl- a nucleoside a single- HMPREF9182_RS03255 HMPREF9182_RS03255 HMPREF9182_RS03255 HMPREF9182_RS02145 UMP and incorporation II HMPREF9182_RS03665 3-phosphate 34 α ω RS09310 II (anaerobic) HMPREF9182_RS03640 [apolipoprotein] acyl-carrier protein palmitoleoyl-sn- acyl-carrier protein acyl-carrier protein HMPREF9182_RS02815a DNA without acyl-carrier protein sn-glycerol 1-[18-hydroxyoeoyl]-2- a queuosine a 2-acyl-1-alkyl- 1-palmitoyl- 1-C16:0- , - roseoflavin D-hexose 6- aspartate--tRNA ligase: a (3R)-3- sn-glycerol oxododec- diphosphate stranded RNA guanine (R)-mevalonate (indol-3-yl)acetate L-cysteine desulfurase an oxidized a [carboxyl-carrier acetate kinase: a [protein]-S- S methyl [18-hydroxy-lioleoyl]-sn in tRNA sn-glycerol 2-myristoyl dicarboxyl-2- 5'-phosphate phosphate a tetrahydrofolate HMPREF9182_RS05440 glycerol 3-phosphate 3-phosphate 5-enoyl-[acp] p 3-phosphate octanoate hydroxydodecanoyl- 6 diphosphate uroporphyrinogen-III thioredoxin asp protein dimer]-N - HMPREF9182_RS05005 methyl-L-cysteine phosphotriester -glycerol 3-phosphate 3-phosphate phosphatidate lysophosphatidate cysteine desulfurase: lipoate--protein ligase A: aspartate--tRNA ligase: [acp] carboxybiotinyl-L-lysine RS07220 HMPREF9182_RS00655 HMPREF9182_RS08015 an L-aspartyl- (3R)-3-hydroxydodecanoyl- an N-acyl-(S-diacyl- acetate RS02415 HMPREF9182_RS04235 a peptide acetyl-CoA methionine synthase: a [lipoyl-carrier protein] [tRNA asp ] [acyl-carrier protein] sn-glyceryl)-L- 1-palmitoyl- N-acetyl-β-D- 1-palmitoyl- [+ 2 isozymes] dihydrofolate reductase: thioredoxin- xanthosine adenosine inosine guanosine a 1-acyl-sn-glycerol (S)-2,3,4,5- a double-stranded coproporphyrinogen III 6 asp a 2,3,4-saturated a 2,3,4-saturated 2- a (5Z)-tetradec- sn-glycerol an apo [peptidyl- wound RNA HMPREF9182_RS07580 N -octanoyl-L-lysine tRNA dehydratase: cysteinyl-[lipoprotein] sn-glycerol a myristoyl-[acp] a malonyl-[acp] glucosaminyl- a myristoyl-[acp] coenzyme A 3'-dephospho- acetyl phosphate sn-glycerol oligonucleotide HMPREF9182_RS00715 disulfide reductase: fatty acyl-[acp] lysophosphatidate 5-enoyl-[acp] 3-phosphate carrier protein] ATP 3-phosphate tetrahydrodipicolinate FMN ATP NaMN ATP an S-sulfanyl-[L- HMPREF9182_RS03650 3-phosphate (1->6)-N-acetyl-α- CoA 3-phosphate bifunctional HMPREF9182_RS03870 1-acyl-sn-glycerol-3- 1-acyl-sn-glycerol-3- beta-ketoacyl-[acyl-carrier- glycerol-3-phosphate 1- holo-ACP synthase: dihydrodipicolinate RS02555 cysteine desulfurase] 1-acyl-sn-glycerol-3- 1-acyl-sn-glycerol-3- oligoribonuclease/PAP RNA helicase: bifunctional riboflavin nicotinate-nucleotide a (2E)-dodec- phosphate acyltransferase: phosphate acyltransferase: protein] synthase II: D-galactosaminyl- O-acyltransferase PlsY: dephospho-CoA kinase: reductase: glycine/betaine reductase purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside alpha-N- HMPREF9182_RS07970 phosphate acyltransferase: phosphate acyltransferase: NrnA: HMPREF9182_RS08320 RS01905 scaffold protein for iron- a [lipoyl-carrier HMPREF9182_RS03255 HMPREF9182_RS03255 HMPREF9182_RS03660 [glycoprotein] HMPREF9182_RS02145 HMPREF9182_RS02880 HMPREF9182_RS07840 B: HMPREF9182_RS02295 kinase/FAD synthetase: adenylyltransferase: 2-enoyl-[acp] 6 phosphorylase: phosphorylase: phosphorylase: phosphorylase: a 2,3,4-saturated 1-palmitoyl- a (7Z)-3-oxo- 1-myristoyl- a holo [peptidyl- HMPREF9182_RS03255 HMPREF9182_RS03255 6 N -L- acetylgalactosaminidase: 3',5'-ADP HMPREF9182_RS01650 HMPREF9182_RS00995 nadD sulfur cluster assembly: protoporphyrinogen IX protein]-N -[(R)- α + (2S,4S)-4-hydroxy-2,3,4,5- 1-palmitoyl-2- nicotinate adenine a reduced tyr dodecanoyl-[acyl-carrier- threonylcarbamoyladenosine 37 HMPREF9182_RS02190 HMPREF9182_RS02195 HMPREF9182_RS02195 HMPREF9182_RS02195 acyl-carrier protein 1,2-diacyl-sn- acyl-carrier protein 2-myristoyl acyl-carrier protein hexadec-7- an N-acetyl- -D- HMPREF9182_RS04700α acyl-carrier protein sn-glycerol carrier protein] ADP coenzyme A H a 1-acyl-2-palmitoyl-sn a nucleoside 5'- an unwound RNA FAD HMPREF9182_RS04230 dihydrolipoyl]-L-lysine tyrosine--tRNA ligase: N-acetyl- -D- tetrahydrodipicolinate gly cis-vaccenoyl dinucleotide serine thioredoxin protein] reductase: -modified tRNA biosynthesis purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside glycerol 3-phosphate phosphatidate enoyl-[acp] galactosalaminyl- 3-phosphate -glycerol 3-phosphate monophosphate serine serine an S-sulfanyl-[cysteine a 7,8-dihydrofolate a 5-methyltetrahydrofolate galactosamine phosphatidate RS06570 RS07425 hydroxymethyltransferase: glyA HMPREF9182_RS05065 an L-tyrosyl- phosphorylase: phosphorylase: phosphorylase: phosphorylase: [glycoprotein] thr thr desulfurase]-[disordered- gcv system: HMPREF9182_RS03665 Tyr thr form scaffold HMPREF9182_RS00660 [tRNA ] HMPREF9182_RS02195 HMPREF9182_RS02190 HMPREF9182_RS02190 HMPREF9182_RS02190 Alcohol Degradation a tRNA Tyr a dodecanoyl-[acp] threonylcarbamoyl- serine serine 1-palmitoyl- an apo-[LYS2 L- a [pyruvate dehydrogenase 1402 RS07325 protein] complex protoporphyrin IX a single a nucleoside N-(5-phosphoribosyl) an (R)-2- (11Z,14Z,17Z)-3- a cytidine phosphoenol AMP synthase: α-D-ribose- a (3Z)-dodec- 6 prephenate β-carotene thr thr [cysteine desulfurase]-S- stranded DNA a palmitoyl-[acp] sn-glycerol a malonyl-[acp] a ribonucleic acid 2-aminoadipyl- coenzyme A halocarboxylate E2 protein] N - phosphoenol in 16S rRNA glycerophosphodiester degradation 3-enoyl-[acp] triphosphate -anthranilate oxoicosatrienoyl-CoA dADP formate ATP pyruvate RS00845 sulfanylcysteine:[acceptor bifunctional a (6S)-5- deferrochelatase/ HMPREF9182_RS00560 1-phosphate VII: 3-phosphate carrier-protein] HAD family : dihydrolipoyl-L-lysine pyruvate acyl-ACP thioesterase: (L-threonylcarbamoyl) 1-acyl-sn-glycerol-3- beta-ketoacyl-[acyl-carrier- DNA-directed RNA phosphoribosylanthranilate holo-ACP synthase: 3-oxoacyl-[acyl-carrier- 16S rRNA (cytidine(1402) anaerobic ribonucleoside- beta-carotene 15,15'- protein]-cysteine methylenetetrahydrofolate formyltetrahydrofolate peroxidase EfeB: 3-oxoacyl-[acyl-carrier- pyrimidine deoxyribonucleotides HMPREF9182_RS03000 HMPREF9182_RS06620 dihydrolipoyl pyruvate kinase: prephenate dehydratase: pyruvate kinase: HMPREF9182_RS02065 adenylate phosphate acyltransferase: protein] synthase II: polymerase subunit beta: isomerase: HMPREF9182_RS07970 protein] reductase: -2'-O)-methyltransferase: triphosphate reductase: monooxygenase: RS08390 sulfurtransferase: dehydrogenase/ 5-formyltetrahydrofolate HMPREF9182_RS00475 protein] reductase: dephosphorylation a glycerophosphodiester HMPREF9182_RS03005 a holo-[LYS2 L- dehydrogenase: HMPREF9182_RS09435 HMPREF9182_RS03170 methylenetetrahydrofolate Trp HAD family hydrolase: HMPREF9182_RS03665 HMPREF9182_RS03170 HMPREF9182_RS08795 thymidylate synthase: a tRNA HMPREF9182_RS03255 aHMPREF9182_RS03660 (5Z)-3-oxo- HMPREF9182_RS02465 HMPREF9182_RS00220 HMPREF9182_RS00660 HMPREF9182_RS08685 HMPREF9182_RS05285 HMPREF9182_RS00075 methenyltetrahydrofolate cyclo-ligase: folate polyglutamylation tryptophan--tRNA ligase: HMPREF9182_RS03665 nucleoside-triphosphate glycerophosphoryl diester a single-stranded a ribonucleoside dipalmitoyl 2-aminoadipyl- 3',5'-ADP HMPREF9182_RS07485 a 2'-O- a [cysteine desulfurase]- reductase [NAD(P)H]: D-ribose 5- acyl-carrier protein acyl-carrier protein tetradec-5- [+ 5 isozymes] 1-(o-carboxyphenylamino)-1'- (3R,11Z,14Z,17Z)-3- keto- HMPREF9182_RS00725 cyclohydrolase: ferroheme b : oligodeoxyribonucleotide 5'-monophosphate an (R)-2- a [pyruvate dehydrogenase dATP pyruvate 1402 dATP all-trans-retinal pyruvate HMPREF9182_RS07585 HMPREF9182_RS06920 HMPREF9182_RS05905 an L-tryptophanyl- beta-ketoacyl-[acyl-carrier- laurate diphosphatase: phosphatidate deoxyribulose 5'-phosphate carrier-protein] a halide anion methylcytidine RS03305 S-sulfanyl-[disordered- an N 6 -L- phosphate enoyl-[acp] a ribonucleic acid E2 protein] N 6 -lipoyl-L-lysine hydroxyicosatrienoyl-CoA phenylpyruvate HMPREF9182_RS03020 Trp protein] synthase II: HMPREF9182_RS03590 HMPREF9182_RS07260 hydroxyacid in 16S rRNA a 5,10- a 5,10- a tetrahydrofolate [tRNA ] 37 sn-glycerol form scaffold HMPREF9182_RS03660 palmitoleate biosynthesis I threonylcarbamoyladenine dCTP dCMP RS05540 methylenetetrahydrofolate methenyltetrahydrofolate trp 3-phosphate protein] complex (from (5Z)-dodec-5-enoate) in tRNA cysteine desulfurase: bifunctional Man GlcNAc -[protein] 1-cis-vaccenoyl- α-D- 38- formate-- serine bifunctional 7 2 an (R)-2- 1-cis-vaccenoyl-sn- a [release factor]- a uridine 3-[(4'-methylthio) HMPREF9182_RS04235 methylenetetrahydrofolate a 3-oxotetradecanoyl- Electron Transfer deoxyuridine a cis- a cis- sn-glycerol a uracil in DNA L-cysteate pyrazinamide tetrahydrofolate ligase: hydroxymethyltransferase: glyA lauroyl-CoA a (5Z)-dodec- (isomer 7A B ) sn-glycerol- halocarboxylate glucopyranose UTP a protein phosphoenol L-glutamine 40 in tRNA butyl]malate RS08430 folylpolyglutamate synthase/ 5'-triphosphate S-methyl-5'-thioadenosine 1,2 1,2 vaccenoyl-[acp] 3-phosphate GTP glycerol-3-phosphate dGDP [+ 2 isozymes] dehydrogenase/ [acp] 5-enoyl-[acp] alpha-1,2-mannosidase: 3-phosphate vaccenoyl-[acp] HAD family hydrolase: 1-phosphate uracil-DNA glycosylase: pyruvate peptide chain release RluA family an S-sulfanyl-[cysteine HMPREF9182_RS00140 dihydrofolate synthase: beta-ketoacyl-[acyl-carrier- nucleotidohydrolase: degradation IV 1-acyl-sn-glycerol-3- glycerol-3-phosphate 1- UTP--glucose-1-phosphate 1-acyl-sn-glycerol-3- Xaa-Pro dipeptidyl- 3-isopropylmalate aspartate RS02225 methenyltetrahydrofolate ATP biosynthesis HMPREF9182_RS04475 HMPREF9182_RS06620 HMPREF9182_RS01685 pyruvate kinase: factor N(5)-glutamine pseudouridine synthase: amidase: desulfurase]-S- a 5,10- HMPREF9182_RS04990 thr 3-oxoacyl-ACP reductase: protein] synthase II: DHAP Man GlcNAc -[protein] phosphate acyltransferase: O-acyltransferase PlsY: GTP cyclohydrolase I FolE: phosphate acyltransferase: peptidase: dehydrogenase: aminotransferase: HMPREF9182_RS06960 6 2 uridylyltransferase: cyclohydrolase: 10 S-methyl-5'- β-D-mannopyranose HAD family hydrolase: uracil-DNA glycosylase: HMPREF9182_RS03170 methyltransferase: HMPREF9182_RS06425 HMPREF9182_RS01190 sulfanyl-[disordered- an N - methylenetetrahydrofolate threonine--tRNA ligase: HMPREF9182_RS08895 a (7Z)-3- HMPREF9182_RS03660 (isomer 6A B ) HMPREF9182_RS032551,2-dicis- HMPREF9182_RS021451-cis-vaccenoyl- 7,8- HMPREF9182_RS04850 HMPREF9182_RS03255 HMPREF9182_RS07270 HMPREF9182_RS01430 HMPREF9182_RS04625 tetrahydrofolate biosynthesis bifunctional nucleoside-triphosphate 1,2 2 HMPREF9182_RS06930 HMPREF9182_RS03020 formyltetrahydrofolate HMPREF9182_RS02425 an L-threonyl- 3-oxoacyl-[acyl-carrier- thioadenosine HMPREF9182_RS07485 HMPREF9182_RS02160 HMPREF9182_RS00555 [+ 3 isozymes] form scaffold bifunctional oxotetradec- 5'-methylthioadenosine/ acyl-carrier protein vaccenoyl- acyl-carrier protein sn-glycerol- dihydroneopterin formate UDP-α-D-glucose 1,2-dicis-vaccenoyl- a peptide a dipeptide 5 38- 7-(methylthio)-2- pyrazine-2- RS06730 10 folylpolyglutamate synthase/ Thr diphosphatase: an (S)-2- an apyrimidinic dGTP pyruvate a [release factor]-N a pseudouridine 3-sulfopyruvate an N - [tRNA ] protein] reductase: ADP a halide anion uracil protein] complex (7,8-dihydropterin- bifunctional folylpolyglutamate synthase/ dihydrofolate synthase: 7-enoyl-[acp] adenosylhomocysteine phosphatidate 3-phosphate 3'-triphosphate phosphatidate oxoheptanoate carboxylate [cysteine desulfurase]-S- a tRNA Thr HMPREF9182_RS03590 hydroxycarboxylate site in DNA -methyl-L-glutamine 40 in tRNA RS06605 4-aminobenzoate 6-yl)methyl formyltetrahydrofolate dihydrofolate synthase: HMPREF9182_RS03665 3-oxoacyl-[acyl-carrier- V-type ATP synthase: dUTP dUMP nucleosidase: sulfanylcysteine:[acceptor folylpolyglutamate synthase/ HMPREF9182_RS05305 dihydropteroatediphosphate synthase: dihydrofolate synthase: HMPREF9182_RS04990 a (3R)-3- protein] reductase: HMPREF9182_RS06795 HMPREF9182_RS08935 protein]-cysteine hydroxytetradecanoyl- HMPREF9182_RS03665 HMPREF9182_RS06800 7,8- HMPREF9182_RS04995 HMPREF9182_RS04990 MTR Man GlcNAc -[protein] 1-palmitoyl- a tRNA precursor with an (S)-2- sn-glycero-3- an insertion sequence 1-oleoyl-sn 3-[(6'-methylthio) an organic sulfurtransferase: bifunctional 8 2 a cis- an apo-[aryl- an unsulfurated an L-cysteinyl- RS01730 a tetrahydrofolate [acp] 3-oxoacyl-ACP reductase: HMPREF9182_RS06810 5-hydroxy-CTP 5-hydroxy-CMP Amino Acid Degradation (isomer 8A B ) sn-glycerol a 5' extension and coenzyme A cys -glycerol 3- an acyl phosphate chorismate HMPREF9182_RS00075 dihydropteroate bifunctional folylpolyglutamate synthase/ 1,2,3 1,2 halocarboxylate phosphoethanolamine 4'-phosphopantetheine ATP [sulfur carrier] Cys element IS30 hexyl]malate hydroperoxide a [cysteine (3R)-3-hydroxymyristoyl- HMPREF9182_RS06815 alpha-1,2-mannosidase: vaccenoyl-[acp] HAD family hydrolase: glycerophosphoryl diester carrier protein] [tRNA ] phosphate RS02170 dihydrofolate synthase: HMPREF9182_RS08895 3-phosphate1-acyl-sn-glycerol-3- a short 3' extensionribonuclease P cysteine desulfurase: 3-isopropylmalate bifunctional superpathway of heme folylpolyglutamate synthase/ ser [acyl-carrier protein] HMPREF9182_RS04475 holo-ACP synthase: aminoacyl-tRNA hydrolase: transposase: 1-acyl-sn-glycerol-3- thiol peroxidase: chorismate mutase: desulfurase]-(S- serine--tRNA ligase: a (3R,7Z)-3- HMPREF9182_RS06825 L-serine degradation protein component: HMPREF9182_RS06620 phosphodiesterase: pantetheine-phosphate HMPREF9182_RS00075 acylphosphatase: dehydrogenase: folylpolyglutamate synthase/ dihydrofolate synthase: HMPREF9182_RS05305 dehydratase: L-glutamine degradation I L-asparagine Man GlcNAc -[protein] phosphate acyltransferase: HMPREF9182_RS07970 HMPREF9182_RS05825 phosphate acyltransferase: sulfanyl) -[disordered- b biosynthesis from HMPREF9182_RS03625 hydroxytetradec- HMPREF9182_RS06830 β-D-mannopyranose 7 2 HAD family hydrolase: HMPREF9182_RS07260 adenylyltransferase: HMPREF9182_RS09985 HMPREF9182_RS04090 HMPREF9182_RS04565 HMPREF9182_RS09340 2 dihydrofolate synthase: HMPREF9182_RS05305 a 5,10- an L-seryl- degradation I (isomer 7A B ) HMPREF9182_RS032551-palmitoyl-2- HMPREF9182_RS06995 a holo-[aryl- [+ 2 isozymes] HMPREF9182_RS01430 form scaffold uroporphyrinogen-III HMPREF9182_RS03650 7-enoyl-[acp] HMPREF9182_RS06835 1,2 1,2 a tRNA precursor with sn-glycerol Cys HMPREF9182_RS03255 [tRNA ser ] Aldehyde Degradation HMPREF9182_RS07485 ethanolamine 3',5'-ADP HMPREF9182_RS04120 a sulfurated a tRNA cys an insertion RS05240 HMPREF9182_RS04990 an N 10 - methylenetetrahydrofolate ∆ 7 ser acyl-carrier protein cis-vaccenoyl a tRNA fragment carrier protein] 3'-dephospho- ala dioleoyl 9-(methylthio)- protein] complex ser 3-hydroxy cis a short 3' extension an (S)-2- 3-phosphate [sulfur carrier] sequence IS30 with a carboxylate an alcohol prephenate RS02725 uroporphyrinogen-III a tRNA a (2E)-tetradec- F0F1 ATP synthase: gln phosphatidate a halide anion CoA 2-oxononanoate bifunctional formyltetrahydrofolate -tetradecenoyl- L-serine ammonia- asn hydroxycarboxylate integrated transposon phosphatidate 2-enoyl-[acp] HMPREF9182_RS08625 methylglyoxal degradation I carbamoyl phosphate folylpolyglutamate synthase/ [acp] dehydratase: lyase, iron-sulfur- myristoyl-[acyl-carrier- HMPREF9182_RS08630 synthase large subunit: asparaginase: dihydrofolate synthase: HMPREF9182_RS03650 dependent, subunit beta: gln RS04270 gln a [cysteine desulfurase]- HMPREF9182_RS08635 HMPREF9182_RS00680 HMPREF9182_RS07985 Man GlcNAc -[protein] a 6-phospho- γ-L-glutamyl-(S)- coproporphyrinogen III protein] reductase: a (2E,7Z)- 9 2 10 a [protein]-L- 3-[(5'-methylthio) HMPREF9182_RS05305 glutathione-peroxide methylglyoxal HMPREF9182_RS05970 an N - an L-methionyl- 2-oxobutanoate [EntF L-seryl- glycerophosphoserine glycerophosphoglycerol 2-hydroxyisobutyramide 3-ethylmalate acetamide [scaffold protein- HMPREF9182_RS03665 HMPREF9182_RS08640 2-aminoprop- asp (isomer 9A B ) DL-allothreonine β-D-galactoside coenzyme A trans-1-propenyl- roseoflavin RS08035 redox reactions tetradeca-2,7- xanthosine-5'-phosphate:L- 1,2,3 1,2,3 Met ATP proline (ω = 180) pentyl]malate 7,8-dihydrofolate di-trans,poly-cis-undecaprenyl pro lactoylglutathione lyase: 2-enoate alpha-1,2-mannosidase: formyltetrahydrofolate [initiator tRNA ] 6-phospho-beta- carrier protein] glycerophosphoryl diester glycerophosphoryl diester 5'-phosphate gln RS01050 gln (2Fe-2S)] complex Cell Structure Biosynthesis proline--tRNA ligase: dienoyl-[acp] HMPREF9182_RS08645 glutamine amido- methionyl-tRNA branched-chain alpha- L-cysteine 3-isopropylmalate 3-isopropylmalate monoglutamate phosphate biosynthesis HMPREF9182_RS01080 HMPREF9182_RS04475 serine galactosidase: holo-ACP synthase: glutamyl aminopeptidase: a myristoyl-[acp] cis-∆ 7 -tetradecenoyl- HMPREF9182_RS08650 keto acid dehydrogenase phosphodiesterase: phosphodiesterase: amidase: bifunctional riboflavin peptidylprolyl isomerase: amidase: lipoate salvage II GSSG HMPREF9182_RS04735 an L-prolyl- (R)-S- ligase (AMP-forming): Man GlcNAc - formyltransferase: hydroxymethyltransferase: glyA HMPREF9182_RS07970 HMPREF9182_RS04895 dehydrogenase: dehydrogenase: 5 2 HMPREF9182_RS08770 HMPREF9182_RS01190 HMPREF9182_RS08960 HMPREF9182_RS01190 UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing) Pro [acp]:NAD+ HMPREF9182_RS08655 L-aspartate degradation I β-D-mannopyranose subunit E2: a holo-[EntF HMPREF9182_RS07260 HMPREF9182_RS07260 S-trans-1- kinase/FAD synthetase: (2E,6E)-farnesyl [tRNA ] lactoylglutathione HMPREF9182_RS00625 [protein] (isomer 5A ) an N-formyl- HMPREF9182_RS03790 D-galactopyranose HMPREF9182_RS01430 HMPREF9182_RS01430 a [lipoyl-carrier protoporphyrinogen IX IPP Pro 3-oxoacyl-[acyl-carrier- 1,2 gly acetaldehyde 3',5'-ADP L-seryl-carrier sn-glycerol sn-glycerol glu propenyl- HMPREF9182_RS00995 diphosphate a tRNA oxidoreductase: HMPREF9182_RS08660 glu HMPREF9182_RS00665 an alcohol ser glycerol 2-hydroxy-2- roseoflavin adenine a [protein]-L- 8-(methylthio)- RS01340 RS03905 a [co-chaperone]- 6 L-methionyl- a tetrahydrofolate 6-phosphate protein]-N - UDP-N-acetyl- protein] reductase: 2-iminopropanoate protein] 3-phosphate 3-phosphate L-cysteine 2-oxovalerate acetate [scaffold protein- HMPREF9182_RS03665 ATP [initiator tRNA met ] NADH CO propanoyl-CoA methylpropanoate dinucleotide proline (ω = 0) 2-oxooctanoate a 7,8-dihydrofolate lipoyl-L-lysine di-trans,octa-cis glutathione- α-D-glucosamine HMPREF9182_RS03665 L-lactaldehyde asp 2 (2Fe-2S)] complex a (7Z)-tetradec- -undecaprenyl disulfide reductase: UDP-N-acetylglucosamine beta-ketoacyl-[acyl-carrier- degradation (anaerobic) aspartate diphosphate HMPREF9182_RS02560 7-enoyl-[acp] (R)-lactate dihydrofolate reductase: (R)-lipoate 1-carboxyvinyltransferase: protein] synthase II: aminotransferase: Man GlcNAc -[protein] N-acetyl-D- protoporphyrin IX undecaprenyl- 8 2 a ring-opened 7- a 7,8-dihydro-8- 3-[(7'-methylthio) RS02360 HMPREF9182_RS00715 HMPREF9182_RS02470 phenylalanine--tRNA ligase: HMPREF9182_RS03660 3-oxoacyl-[acyl-carrier- (S)-lactaldehyde HMPREF9182_RS04625 acetoacetyl-CoA H O acetyl-CoA an N-modified AsbD acyl- nicotinate PRPP 4-guanidinobutyramide a 7,8-dihydrofolate a DNA segment propionamide acrylamide RS01915 phe (isomer 8A B ) methylguanine in DNA 2 VibB coenzyme A coenzyme A galactosamine a [chaperone-ATP]- diphosphate phosphatase: HMPREF9182_RS01590 protein] reductase: pyruvate oxaloacetate 1,2,3 1,3 aminoacyl-[tRNA] oxoguanine in DNA carrier protein heptyl]malate lipoate--protein ligase A: deferrochelatase/ UDP-N-acetylglucosamine lactaldehyde reductase: alpha-1,2-mannosidase: DNA-formamidopyrimidine hydroxymethylglutaryl- DNA-formamidopyrimidine 6-phosphate nicotinate [co-chaperone]- a tetrahydrofolate HMPREF9182_RS04260 HMPREF9182_RS01600 an L-phenylalanyl- a 3-oxohexadecanoyl- HMPREF9182_RS03665 aminoacyl-tRNA hydrolase: holo-ACP synthase: holo-ACP synthase: N-acetylglucosamine-6- 3-isopropylmalate HMPREF9182_RS00655 peroxidase EfeB: glutathione 1-carboxyvinyltransferase: HMPREF9182_RS04770 HMPREF9182_RS04475 glycosylase: CoA synthase: glycosylase: phosphoribosyltransferase: amidase: dihydrofolate reductase: recombinase RecA: amidase: amidase: [scaffold protein- di-trans,octa-cis- [tRNA Phe ] [acp] (S)-propane- Man GlcNAc - HMPREF9182_RS05825 HMPREF9182_RS07970 HMPREF9182_RS07970 phosphate deacetylase: dehydrogenase: HMPREF9182_RS00475 HMPREF9182_RS09275 beta-ketoacyl-[acyl-carrier- pyruvate β-D-mannopyranose 5 2 HMPREF9182_RS02885 HMPREF9182_RS07315 HMPREF9182_RS02885 HMPREF9182_RS03865 HMPREF9182_RS01190 HMPREF9182_RS00715 HMPREF9182_RS05335 HMPREF9182_RS01190 HMPREF9182_RS01190 (2Fe-2S)] complex undecaprenyl phosphate a tRNA Phe 1,2-diol [protein] (isomer 5A ) 2,6-diamino-4- an N-modified an uncharged a holo-[VibB aryl- a holo-[AsbD acyl- HMPREF9182_RS03975 HMPREF9182_RS01430 RS06140 (lipoyl)adenylate α 3-oxoacyl-ACP reductase: protein] synthase II: 1,2 an apurinic site an apurinic site 7,8-dihydro- 3',5'-ADP 3',5'-ADP D-galactosamine RS05030 lipoate salvage I UDP-N-acetyl- - hydroxy-5-(N-methyl) HMG-CoA amino acid tRNA carrier protein] acetate NaMN a DNA segment in 10-(methylthio)- ferroheme b HMPREF9182_RS08895 HMPREF9182_RS03660 within DNA 8-oxoguanine carrier protein] 6-phosphate 4-guanidinobutanoate a folate propanoate acrylate D-glucosamine- within DNA formamidopyrimidine reverse orientation 2-oxodecanoate lipoate--protein ligase A: 3-oxoacyl-[acyl-carrier- a (9Z)-3- thiamine salvage III enolpyruvate HMPREF9182_RS00655 (R)-lipoate protein] reductase: oxohexadec- a [chaperone- UDP-N- glycine glycine a [glycine- lipoate--protein ligase A: HMPREF9182_RS03665 9-enoyl-[acp] Man GlcNAc -[protein] 3 D-ribulose RS01410 RS09535 an [2Fe-2S] acetylenolpyruvoylglucosamine met Aromatic Compound Biosynthesis 8 2 RNase III mRNA 5-amino-4- an N -methyladenine [EntB aryl- a monocarboxylic 3-[(3'-methylthio) betaine betaine ADP]-[disordered- thiamine cleavage complex HMPREF9182_RS00655 a (3R)-3- 3-oxoacyl-ACP reductase: (isomer 8A B ) glycine betaine PRPP GSSH sulfite 3-oxopropanoate (R)-pantoate methylglyoxal cluster protein methionine--tRNA ligase: 1,2,3 2,3 processing substrate imidazolecarboxyamide in DNA coenzyme A L-cystathionine acid amide propyl]malate 5-phosphate 6 acyl carrier protein activation reductase: carrier protein] ammonium CO ATP form scaffold thiamine diphosphokinase: H protein] N - an L-methionyl- hydroxyhexadecanoyl- HMPREF9182_RS08895 Inorganic Nutrient Metabolism alpha-1,2-mannosidase: glycine/betaine reductase adenine DNA-3-methyladenine 2 rhodanese domain- (lipoyl)adenylate HMPREF9182_RS08725 III: holo-ACP synthase: cystathionine beta-lyase: malonic semialdehyde 3-isopropylmalate ribulose-phosphate protein] complex lipoyl-L-lysine HMPREF9182_RS08550 [elongator [acp] 3-oxoacyl-[acyl-carrier- chorismate biosynthesis I HMPREF9182_RS04475 phosphoribosyltransferase: glycosylase I: containing protein: ketopantoate reductase: amidase: glyoxalase: HMPREF9182_RS07055 HMPREF9182_RS02400 B: HMPREF9182_RS02295 carbamate kinase: reductase: dehydrogenase: 3-epimerase: thiamine UDP-N-acetylmuramate elongator Met Man GlcNAc -[protein] HMPREF9182_RS07970 HMPREF9182_RS01225 RS05000 an apo acyl- lipoate--protein ligase A: tRNA ] (3R)-3-hydroxypalmitoyl- protein] reductase: β-D-mannopyranose 7 2 RNase III processing HMPREF9182_RS01175 HMPREF9182_RS05385 HMPREF9182_RS08450 HMPREF9182_RS08175 HMPREF9182_RS00900 HMPREF9182_RS01190 HMPREF9182_RS07165 RS07865 coenzyme A Met urea cycle (isomer 7A B ) an mRNA fragment trimethylamine acetyl phosphate a holo-[EntB aryl- HMPREF9182_RS02580 HMPREF9182_RS01430 HMPREF9182_RS07050 diphosphate carrier protein dehydrogenase: tRNA [acyl-carrier protein] 1,2,3 2 an apurinic site carbamoyl holo-ACP synthase: HMPREF9182_RS00655 HMPREF9182_RS03665 D-erythrose 4-phosphate thiosulfate disproportionation product mRNA AICAR 3-methyladenine 3',5'-ADP pyruvate L-homocysteine thiosulfate glutathione 6-(methylthio)- D-xylulose HMPREF9182_RS02235 dehydratase: a (3R,9Z)-3- within DNA carrier protein] phosphate 3-hydroxypropanoate 2-dehydropantoate a monocarboxylate (R)-lactate an [Fe-S cluster a [disordered- a [lipoyl-carrier HMPREF9182_RS07970 a [lipoyl-carrier IV (rhodanese) 2-oxohexanoate 5-phosphate a holo acyl- ala UDP-N-acetyl- hydroxyhexadec- biosynthesis form [Fe-S] cluster protein]-N 6 - 3',5'-ADP protein]-N 6 - HMPREF9182_RS03650 3-deoxy-7- arg carrier protein α-D-muramate 9-enoyl-[acp] chaperone]-ATP scaffold protein] lipoyl-L-lysine lipoyl-L-lysine glu a (2E)-hexadec- phosphoheptulonate thiosulfate RS00465 ∆ 9 RS08970 Lys 3-hydroxy cis synthase: rhodanese domain- Man GlcNAc -[protein] RNase R degradation a DNA containing an (S)-2- UDP-N-acetyl- D-ribulose a tRNA 2-enoyl-[acp] 6 2 maltopentaose D-glucopyranose a 5S rRNA (R)-propane- α-amylose UDP-N-acetylmuramate- lysine--tRNA ligase: -hexadecenoyl- containing protein: (isomer 6A B ) an apurinic/ [DNA] α-D-glucosamine a uridine in tRNA a cytosine in DNA glutamate racemase: HMPREF9182_RS07965 1,2 1 precursor substrate RNA halocarboxylate a type IV prepilin a protein 1,2-diol 5-phosphate -L-alanine ligase: HMPREF9182_RS02540 an L-lysyl- palmitoyl-[acyl-carrier- [acp] dehydratase: alpha-1,2-mannosidase: 4-alpha-glucanotransferase: apyrimidinic site exodeoxyribonuclease III: haloacid dehalogenase: HMPREF9182_RS03595 HMPREF9182_RS08175 ribonuclease M5: ribonuclease R: toxin PezT: tRNA dihydrouridine DNA cytosine 1,4-alpha-glucan HMPREF9182_RS08330 Lys protein] reductase: 3-deoxy-D-arabino- HMPREF9182_RS04475 III: prepilin peptidase: endopeptidase: lactaldehyde reductase: phosphoribulokinase: [tRNA ] HMPREF9182_RS03650 ammonium sulfite thiocyanate HMPREF9182_RS06675 HMPREF9182_RS07025 HMPREF9182_RS02865 HMPREF9182_RS08710 HMPREF9182_RS03015 branching protein GlgB: heptulosonate 7-phosphate Man GlcNAc - HMPREF9182_RS08700 a 2'- HMPREF9182_RS03140 HMPREF9182_RS07805 HMPREF9182_RS04545 synthase DusB: methyltransferase: lys HMPREF9182_RS03665 a (2E,9Z)- β 5 2 a double-stranded a nucleoside 5'- HMPREF9182_RS04770 HMPREF9182_RS06890 RS09585 RS08480 -D-mannopyranose maltose maltotetraose a mature 5S-rRNA a 3'-terminal a 5'-phospho- [+ 3 isozymes] HMPREF9182_RS06520 HMPREF9182_RS02775 HMPREF9182_RS08595 D-glt UDP-N-acetyl-α-D- hexadeca-2,9- [protein] (isomer 5A ) a diribonucleotide deoxyribonucleoside [DNA] an (R)-2- a cleaved type UDP-N-acetyl-α-D- L-arginino- carbamoyl phosphate 1,2 oligonucleotide monophosphate unsaturated sugar [DNA] a peptide a peptide a peptide muramoyl-L-alanine 3-dehydroquinate synthase: L-ornithine 5'-monophosphate a halide anion IV prepilin a 5,6-dihydrouridine a 5-methylcytosine D-ribulose-1,5- amylopectin a palmitoyl-[acp] dienoyl-[acp] synthase large subunit: hydroxyacid glucosamine 3'-phosphate (R)-lactaldehyde palmitoleoyl-[acp]:NAD+ HMPREF9182_RS09405 succinate Detoxification in tRNA in DNA bisphosphate HMPREF9182_RS00680 UDP-N-acetylmuramoyl-L- oxidoreductase: acyl-ACP thioesterase: 3-dehydroquinate RS05550 alanine--D-glutamate ligase: HMPREF9182_RS03665 carbamoyl RS06945 his HMPREF9182_RS02065 reactive oxygen oxidized GTP and dGTP detoxification Man GlcNAc -[protein] a long-linear γ-L-glutamyl-[(S γ-L-glutamyl-(S)- an N-terminal L- a (1->4)- HMPREF9182_RS03105 histidine--tRNA ligase: phosphate superoxide 9 2 α-D-glucopyranose maltohexaose D-glucopyranose 7,8-dihydrofolate + an α-limit dextrin (2R,3S)-3- type I 3- ornithine species degradation (isomer 9A B ) α-D-glucan NADPH H D-proline dihydrolipoate a tripeptide 2-phosphoglycolate pyridoxal ethylene glycol α-D-glucan HMPREF9182_RS05450 a palmitoleoyl-[acp] radicals degradation 1,2,3 1,2,3 monoglutamate )-allyl]-L-cysteine methyl-L-cysteine glutamyl-[protein] isopropylmalate an L-histidyl- palmitate dehydroquinate carbamoyltransferase: alpha-1,2-mannosidase: 4-alpha-glucanotransferase: 4-alpha-glucanotransferase: glutamyl aminopeptidase: peptidase T: glutamyl aminopeptidase: glutamyl aminopeptidase: His dihydrofolate reductase: phosphoglycolate 3-oxoacyl-[acyl-carrier- 3-isopropylmalate 1,4-alpha-glucan UDP-N-acetyl- [tRNA ] HMPREF9182_RS04475 proline reductase: 4-alpha-glucanotransferase: dehydratase: aroD HMPREF9182_RS00780 superoxide dGTP GTP HMPREF9182_RS06675 HMPREF9182_RS06675 HMPREF9182_RS00715 HMPREF9182_RS04895 HMPREF9182_RS01990 HMPREF9182_RS04895 HMPREF9182_RS04895 lactaldehyde reductase: branching protein GlgB: lys α-D-muramoyl-L- a tRNA His superoxide Man GlcNAc -[protein] HMPREF9182_RS03435 phosphatase: protein] reductase: dehydrogenase: acyl-ACP thioesterase: 8 2 HMPREF9182_RS06675 HMPREF9182_RS04770 RS05260 L-citrulline β-D-mannopyranose a short glucan a short glucan maltose maltopentaose + tetrahydropteroyl a proteinogenic S-methyl- HMPREF9182_RS08595 RS07340 alanyl-D-glutamate 3-dehydroshikimate superoxide dismutase: (isomer 8A B ) NADP glu S-allyl-L-cysteine a dipeptide glu a protein glu HMPREF9182_RS06535 HMPREF9182_RS03665 HMPREF9182_RS01430 HMPREF9182_RS02065 superoxide dismutase: 1,2,3 2,3 (R)-lipoate 5-aminopentanoate α mono-L-glutamate amino acid a -limit dextrin L-cysteine 4-methyl-2- HMPREF9182_RS03230 HMPREF9182_RS03230 glycolaldehyde starch UDP-N-acetylmuramoyl- hydrogen with short branches glycolate 4-pyridoxolactone palmitoyl-CoA palmitoleate shikimate dehydrogenase: shikimate dehydrogenase: 8-oxo-dGTP 8-oxo-GTP oxopentanoate L-alanyl-D-glutamate- D-ala HMPREF9182_RS09400 HMPREF9182_RS09400 hydrogen peroxide RS08500 -L- lysine ligase: gly glycine--tRNA ligase: peroxide 8-oxo-dGTP RS07235 Man GlcNAc -[protein] HMPREF9182_RS03400 HMPREF9182_RS03940 diphosphatase: 7 2 GlcMan GlcNAc a [lipoyl-carrier lysine within a (1->4)- a glucosylated a (1->4)- D-alanine--D-alanine ligase: shikimate maltohexaose maltose a maltodextrin D-glucopyranose an α-D-galactoside a single a ribonucleoside 9 2 (R)-lipoate (R)-lipoate stachyose formate CTP a (1->4)-α-D-glucan β-D-fructofuranose HMPREF9182_RS03945 (isomer 7A B ) -[protein] α-D-glucan glycogenin α-D-glucan HMPREF9182_RS06955 1,2,3 3 stranded DNA triphosphate protein]-L-lysine gcv protein H HMPREF9182_RS09125 a glycyl-[tRNA Gly ] alpha-1,2-mannosidase: 4-alpha-glucanotransferase: 4-alpha-glucanotransferase: alpha-galactosidase: alpha-1,2-mannosidase: alpha-galactosidase: UDP-N-acetyl-α-D- DNA primase: lipoate--protein ligase A: lipoate--protein ligase A: anaerobic ribonucleoside- 1,4-alpha-glucan 1,4-alpha-glucan 1,4-alpha-glucan 1,4-alpha-glucan shikimate kinase: [+ 3 isozymes] 8-oxo-GMP O HMPREF9182_RS04475 HMPREF9182_RS05410 fructokinase: muramoyl-L-alanyl-γ- a tRNA Gly 2 HMPREF9182_RS06675 HMPREF9182_RS06675 HMPREF9182_RS05410 HMPREF9182_RS04475 HMPREF9182_RS00655 HMPREF9182_RS00655 branching protein GlgB: branching protein GlgB: branching protein GlgB: branching protein GlgB: D-alanyl-D-alanine HMPREF9182_RS09430 Man GlcNAc -[protein] HMPREF9182_RS01840 D-glucosyl- Man GlcNAc - a [glycine-cleavage triphosphate reductase: HMPREF9182_RS04410 RS01300 O H O hydroxyl radical 8-oxo-dGMP β-D-mannopyranose 6 2 D-glucopyranose maltoheptaose maltose a maltodextrin a non galactosylated α ssDNA/pppN(pN) 8 2 a [lipoyl-carrier protein]- α-D-galactose raffinose D-glutamyl-L-lysine 2 2 -D-galactose α α HMPREF9182_RS05285 HMPREF9182_RS08595 HMPREF9182_RS08595 HMPREF9182_RS08595 HMPREF9182_RS08595 RS04250 (isomer 6A ) galactose acceptor (1->3)- - [protein] (isomer 6 complex H protein] 1,2,3 hybrid N -lipoyl-L-lysine dCTP a (1,6)-α-D-glucosyl- shikimate 3-phosphate n -1 D-mannose 8A B ) N 6 -lipoyl-L-lysine F6P a GlgE-glycogen a glycogen a glycogen UDP-N-acetylmuramoyl- 1,2,3 1,2 (1,4)-α-glucan tripeptide--D-alanyl- 3-phosphoshikimate 1- RS06735 D- alanine ligase: met carboxyvinyltransferase: methionine--tRNA ligase: Man GlcNAc -protein a plant soluble p-nitrophenyl-α-D- N-acetyl-β- a peptide with CTP HMPREF9182_RS09130 7 2 + RS03845 HMPREF9182_RS09425 D-glucopyranose maltotetraose D-glucopyranose a glucan maltotriose melibionate hydrogencarbonate H raffinose formate UTP sec acetylxylan carbonic acid HMPREF9182_RS08725 an L-methionyl- (isomer 7A B ) heteroglycan galactopyranoside neuraminate an N-terminal a tRNA ser 1,2,3alpha-1,2-mannosidase:1 4-alpha-glucanotransferase: 4-alpha-glucanotransferase: alpha-galactosidase: 4-alpha-glucanotransferase: N-acetylneuraminate lyase: alpha-galactosidase: alpha-galactosidase: acetylxylan esterase: nucleoside-triphosphate α Met 5-enolpyruvoyl- carbonic anhydrase: anaerobic ribonucleoside- L-alanine carbonic anhydrase: UDP-N-acetyl- -D- [initiator tRNA ] aminopeptidase N: serine--tRNA ligase: diphosphatase: met RS07480 met initiator tRNA Met shikimate 3-phosphate HMPREF9182_RS04475 HMPREF9182_RS06675 HMPREF9182_RS06675 HMPREF9182_RS05410 HMPREF9182_RS06675 HMPREF9182_RS06775 HMPREF9182_RS05410 HMPREF9182_RS06985 HMPREF9182_RS05410 triphosphate reductase: HMPREF9182_RS06740 HMPREF9182_RS06985 muramoyl-L-alanyl- Man GlcNAc -[protein] a plant soluble N-acetyl-β-D- HMPREF9182_RS00935 HMPREF9182_RS03625 HMPREF9182_RS03590 γ β-D-mannopyranose 6 2 maltose maltose maltotriose D-glucopyranose a glucan D-gluconate α-D-galactose sucrose α-D-galactose V-type ATP -D-glutamyl-L-lysyl- (isomer 6A B ) heteroglycan 4-nitrophenol D-galactopyranose pyruvate H O CO HMPREF9182_RS05285 an L-seryl- acetate xylan CO H O + + chorismate synthase: 1,2 1 mannosamine 2 2 2 2 CMP H H dUTP a peptide ala sec synthase met RS08130 met D-alanyl-D-alanine HMPREF9182_RS09410 [tRNA ] F0F1 ATP chorismate H + H + RS01525 a branched- synthase chain an amino amino acid N-acetyl-α-D-galactosamine 1-phosphate a sugar 6- a sugar 6- a sugar 6- a sugar 6- a sugar 6- D-fructose acid D-mannose RS08135 2-dehydro- a branched- an L-sorbose 1-phosphate N-acetyl-α-D-galactosamine 1-phosphate 6-phosphate an L-sorbose 1-phosphate a β- phosphate phosphate phosphate phosphate phosphate 1-phosphate an amino an amino an amino an amino an amino an amino a carbohydrate sn-glycerol putrescine 3,5- D-fructose 3-deoxy-D- chain D-fructose 1-phosphate D-fructose 1-phosphate D-fructose 1-phosphate glucoside 6- a C4- D-trehalose D-glucose 6- a nucleotide an antibiotic acid acid acid acid acid acid an aromatic an aromatic a carbohydrate a carbohydrate a carbohydrate 3-phosphate queuosine phosphonate bacitracin spermidine dimethoxytoluene 1-phosphate gluconate ammonium amino acid D-mannose 6-phosphate D-mannose 6-phosphate D-mannose 6-phosphate phosphate dicarboxylate 6-phosphate phosphate carboxylate carboxylate predicted predicted ABC predicted predicted predicted predicted predicted predicted predicted ABC transporter predicted ABC PEP-driven PEP-driven PEP-driven PEP-driven PEP-driven PEP-driven PEP-driven RS08140 RS05810 RS05345 RS08490 RS04630 RS03630 RS08950 RS04345 RS00860 RS01875 RS03205 RS09500 RS07605 RS00850 RS01820 RS06725 RS03095 RS06005 RS04890 RS05570 RS06925 RS08665 RS08785 RS03090 RS09255 RS02215 RS07900 RS08045 RS00760 RS04350 RS06690 RS00925 RS04275 RS01055 RS08115 RS01180 transporter RS08865 RS07410 RS07145 RS07705 RS07215 of a RS04445 RS04715 RS01955 transporter of RS03610 RS06090 RS06095 RS07695 RS04780 RS00835 RS09315 RS03485 RS08280 RS01605 RS06180 RS00370 RS06430 RS01815 RS05230 RS02515 RS01865 RS02810 RS09570 RS08815 RS03290 RS05535 RS00605 RS02220 RS09725 RS05185 RS03925 RS07275 RS02650 RS07075 RS05190 RS08485 RS05090 RS05195 RS07415 RS04430 RS08150 RS03495 RS07520 RS02615 RS09140 RS08545 RS04910 RS07700 RS02255 RS05220 RS08165 RS03540 RS00590 RS00215 transporter transporter transporter transporter transporter transporter transporter of an branched- a carbohydrate of a sugar of a sugar of a sugar of a sugar of a sugar of D-fructose of D-mannose amino acid chain amino acid

putrescine 3,5- 2-dehydro- a branched- a branched- L-sorbose N-acetyl-α-D-galactosamine N-acetyl-α-D-galactosamine a C4- a sugar a sugar a sugar a sugar a sugar D-fructose D-fructose an antibiotic an amino an amino an amino an amino an amino an amino an amino a carbohydrate a carbohydrate a carbohydrate a carbohydrate D-mannose sn-glycerol a β-glucoside queuosine trehalose D-glucose phosphonate bacitracin a nucleotide 3-deoxy-D- an aromatic an aromatic chain chain D-fructose D-fructose L-sorbose spermidine dimethoxytoluene ammonium acid acid acid acid acid acid acid 3-phosphate dicarboxylate gluconate carboxylate carboxylate amino acid amino acid D-mannose D-mannose D-fructose D-mannose This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.