Authors: Pallavi Subhraveti Ron Caspi Quang Ong Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Spne170187Cyc: Streptococcus pneumoniae TIGR4; ATCC BAA-334 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari L-ascorbate L-ascorbate lactose lactose lactose D-mannitol D-cellobiose D-cellobiose D-cellobiose D-cellobiose

predicted predicted predicted predicted predicted predicted predicted predicted PEP-driven PEP-driven PEP-driven PEP-driven PEP-driven PEP-driven PEP-driven PEP-driven RS11185 RS04730 RS00640 RS02805 RS04210 RS00490 RS00740 RS02690 RS08240 RS11220 RS01150 RS00735 RS05470 RS06915 RS02510 RS01975 RS10335 RS09715 RS08425 RS03685 RS06765 RS09335 RS08700 RS00165 RS11105 RS06650 RS07815 RS10400 RS08730 RS10745 RS06200 RS06975 RS00170 RS01360 RS08680 RS05215 RS08670 RS03345 transporter transporter RS10870 RS03330 RS08775 RS03415 RS00555 RS05845 RS11330 RS06645 RS08945 RS10760 RS11395 RS10560 RS09120 RS00700 RS04990 RS08565 RS02680 RS08030 RS03955 RS07910 RS06155 RS10165 transporter RS02340 transporter transporter RS03405 RS08445 RS05015 RS09285 RS02970 RS05780 RS00400 RS11140 RS01410 RS05895 RS00825 RS00210 RS00040 RS09865 RS08290 RS06865 RS01165 RS11350 RS07635 RS00900 RS10355 RS04140 RS10800 RS07040 RS06680 RS09810 RS06075 RS10665 RS00795 RS05125 RS10685 RS08950 RS06185 RS06575 RS09280 RS06310 RS11065 RS10070 RS02390 RS10260 RS05365 RS07150 RS03840 RS06600 RS02555 RS06640 sortase transporter transporter transporter of L- of L- of D- of D- of D- of lactose of lactose of D-mannitol RS12300 ascorbate ascorbate cellobiose cellobiose cellobiose RS08925 lactose 6'- D-cellobiose phosphate 6'- lactose 6'- lactose 6'- D-mannitol L-ascorbate L-ascorbate D-cellobiose phosphate D-cellobiose D-cellobiose phosphate phosphate 1-phosphate RS12200 6-phosphate 6-phosphate 6'- 6'- 6'- foldase phosphate phosphate phosphate

RS04740 RS10410 Aminoacyl- Respiration RS10795 tRNA Charging Carbohydrate Degradation an inactive quinoxaline-2- a glycopeptide- an [apo BCAA 4-deoxy-β-D-gluc- 2-(2-carboxy-4- a [protein] N- a glutathione- a peptide with 5'-deoxy-5'- 4-hydroxy- 4-hydroxy- a [protein]- gln a reduced 34 π glutaminyl-tRNA 2-oxoisovalerate decarboxylation to isobutanoyl-CoA lactose and galactose 4 methylthiazol-5- a purine 2'- glutathione a cytidine ribonucleoside SAM acyl-carrier protein carboxyl adenylate D-mannosyl-N dehydrogenase 4-enuronosyl- HMP-PP terminal-formyl- S-conjugate N-terminal 5- chloroadenosine 2-nonenal- 2-nonenal lys GTP a protein N -phospho- ATP RS00595 RS07895 fucose degradation D-arabinose degradation I sucrose degradation III (sucrose invertase) Aldehyde Degradation flavodoxin hypoxanthine 6 Ile2 ATP biosynthesis via degradation I triphosphate PRPP -(N-acetyl-D- (S)-3-methyl-2- E2 protein] N 2-sulfate-(1,3) yl)ethyl phosphate L-methionine deoxyribonucleoside oxo-L-proline glutathione in tRNA formate L-histidine formate biotin an [apo BCAA histidine RS03350 transamidation lactose 6'- reductase glucosaminyl) oxopentanoate -lipoyl-L-lysine -N-acetyl-β-D- conjugate dehydrogenase β-L-fucopyranose D-arabinopyranose sucrose methylglyoxal degradation I gamma- purine-nucleoside glutathione S- 6 phosphate L-lactaldehyde acyl carrier -asparagine galactosamine thiamine peptide Pyrrolidone- tRNA(Ile) ATP- Glu E2 protein] N branched-chain 2 glutamyl phosphorylase: : family protein: alpha-keto acid L-fucose degradation anaerobic protein: xanthine branched-chain phosphate deformylase: purine-nucleoside carboxylate -lysidine anaerobic dependent anaerobic bifunctional RS06060 glutamyl- -lipoyl-L-lysine 6-phospho-beta- L-fucose : : SP_RS04065 gamma- SP_RS07645 SP_RS00150 RS02585 Gln mutarotase: beta- methylglyoxal (anaerobic) SP_RS00230 phosphoribosyltransferase: alpha-keto acid synthase: SP_RS07640 phosphorylase: peptidase 2: synthetase: ribonucleoside- Clp protease ribonucleoside- biotin-- tRNA dehydrogenase galactosidase: SP_RS11010 ribonucleoside- endo-beta-N- unsaturated SP_RS10555 glutamyl histidine dihydrolipoyl SP_RS11045 fructofuranosidase: lactoylglutathione SP_RS09165 dehydrogenase SP_RS03515 SP_RS04065 SP_RS10415 purine-nucleoside SP_RS00055 triphosphate proteolytic triphosphate [acetyl-CoA- RS04750 synthetase: subunit E2: SP_RS02355 (S)-lactaldehyde triphosphate acyl carrier acetylglucosaminidase: chondroitin peptide hydrolase: phosphatase dehydrogenase: D-ribulose SP_RS08910 : SP_RS03580 hypoxanthine-guanine subunit E2: purine-nucleoside gamma- phosphorylase: 4-hydroxy- reductase: subunit: reductase: carboxylase] SP_RS10540 SP_RS05730 α lactaldehyde reductase protein: SP_RS02450 disaccharide thiamine deformylase: Pyrrolidone- SP_RS05395 an L-glutamyl- SP_RS05725 6-phospho-beta- -L-fucopyranose glutamyl SP_RS04085 2-nonenal- SP_RS00980 family protein: SP_RS00980 synthetase/ lactoylglutathione activating SP_RS02065 phosphoribosyltransferase: SP_RS05730 hydrolase: phosphate SP_RS07155 phosphorylase: carboxylate 34 SP_RS03655 RS09675 [tRNA Gln ] galactosidase: D-ribulokinase: reductase: endo-beta-N- hydrolase: gamma- glutathione a lysidine SP_RS04880 RS09740 β lyase: SP_RS04770 SP_RS00060 SP_RS04085 Ile2 biotin operon SP_RS05825 L-fucose -D-fructofuranose D-glucopyranose (R)-S- SP_RS11005 protein: acetylglucosaminidase: SP_RS01565 synthase: peptidase 1: glutamyl in tRNA a [protein]- glutamyl-tRNA(Gln) an [apo BCAA SP_RS11055 (S)-propane- SP_RS05395 5-chloro-5- conjugate repressor: an [apo BCAA dehydrogenase isomerase: lactoylglutathione SP_RS00995 a quinoxaline-2- SP_RS04785 an [apo BCAA dehydrogenase SP_RS03550 SP_RS04215 hydrolase: L-histidine RS08655 dehydrogenase 6 D-galactopyranose 1,2-diol an N-terminal L- deoxyribose amidotransferase E2 protein] N -S-[2- SP_RS11010 glucokinase: 6 formate 2-deoxy-α- adenine SP_RS09440 E2 protein] N 6 6-phosphate D-ribulose 1-phosphate carboxyl-[aryl- E2 protein] N -S-[2- 5-dehydro-4- N-acetyl-D- SP_RS10555 dGTP a peptide a peptide dATP subunit A: gatA methylpropanoyl]dihydrolipoyl- SP_RS03280 hydroxyacylglutathione AMP methionyl-[protein] an (L- 1-phosphate -dihydrolipoyl- fructokinase: an active carrier protein] IMP a glycopeptide- N-acetyl-D- methylbutanoyl]dihydrolipoyl- deoxy-2-O-sulfo- galactosamine D-ribose 1- a purine base RS03290 L-lysine galactose-6- L-fuculose hydrolase: SP_RS08125 a flavodoxin thiamine cysteinylglycine) Glu an L-glutaminyl- L-lysine SP_RS08515 D-glucopyranose 5'-deoxyadenosine met ribonucleoside D-mannosyl- glucosamine- L-lysine D-glucuronate phosphate 5-oxo-L-proline a peptide 4-hydroxy-2- biotinyl-5'- RS08335 Gln phosphate D-ribulose-phosphate semiquinone phosphate -S-conjugate [tRNA ] 6-phosphate triphosphate 4 isomerase L-fuculokinase: aldolase: SP_RS11050 (R)-lactate N -N-acetyl- asparagine nonenal-[Cys- Glu adenylate reductase RS01610 subunit LacB: SP_RS11055 glucose-6- D-glucosamine Gly] conjugate branched-chain L-fuculose phosphate RS04500 tRNA charging SP_RS05860 DHAP glycolaldehyde alpha-keto acid 1-phosphate isomerase: α RS05340 galactose-6- a [formate C an N-formyl-L- an [apo BCAA 4-deoxy-β-D-gluc- 4-hydroxy-2- a 6-(N-acetyl- - 5'-deoxy-5'- methyl β-D-glucoside a 3- a (7Z,10Z,13Z a (7Z)-3- a [protein]- a [protein]- pgi 1-palmitoylglycerol a β-D-galactoside a ribonucleoside a 3-oxotetracosanoyl- τ dehydrogenase phosphate glycolaldehyde a reduced flavodoxin SAM a myristoyl-[acp] methionylaminoacyl- dehydrogenase 4-enuronosyl- a purine formate oxoglutarate D-glucosaminyl)- 6-phosphate oxodocosanoyl- ,16Z,19Z)-3- oxotetradec- N -phospho- N-phospho- Gly asp Phe pyruvate acetyltransferase]-glycine 3-phosphate triphosphate ATP roseoflavin fluoroadenosine dGDP gly a tRNA tRNA asp phe a tRNA subunit E2: fuculose dehydrogenase: 4-methyl-2- 6 [acp] RS08215 isomerase F6P tRNA E2 protein] N (1,3)-N-acetyl-- ribonucleoside 5'-phosphate 1-phosphatidyl- hypothetical [acp] hypothetical oxodocosa- 7-enoyl-[acp]beta-ketoacyl- L-histidine L-histidine ala RS02020 ala SP_RS05730 phosphate SP_RS05545 oxopentanoate histidine histidine ribonucleoside- subunit LacA: beta-D- -lipoyl-L-lysine D-glucosamine 1D-myo-inositol protein: protein: 7,10,13,16,19-hypothetical ACP a tRNA Ala ala asn tRNA Asn thr a tRNA Thr ile a tRNA Ile Glu a tRNA glu arg a tRNA Arg tyr a tRNA Tyr his a tRNA His trp a tRNA Trp leu a tRNA Leu pro a tRNA Pro ser a tRNA ser val a tRNA Val cys a tRNA Cys lys a tRNA Lys elongator tRNA Met met initiator tRNA Met met aldolase: pyruvate formate bifunctional 2-keto- purine-nucleoside 6-phospho- phosphatase phosphatase diphosphate RS06510 Gln SP_RS05865 1-acyl-sn-glycerol- 6-sulfate anaerobic SP_RS00205 SP_RS00205 pentaenoyl-[acp] reductase: glycine--tRNA aspartate--tRNA phenylalanine--tRNA ligase gln a tRNA glycolate D-allose galactosidase: peptide 4-hydroxyglutarate phosphorylase: beta- protein: family protein: family protein: reductase predicted SP_RS11050 lyase-activating 3-phosphate purine-nucleoside ribonucleoside- bifunctional riboflavin GlcNAc-PI de- SP_RS02080 subunit beta: SP_RS07245 ligase: SP_RS10780 subunit beta: SP_RS02875 D-tagatofuranose degradation Amine and Polyamine Degradation SP_RS08355 deformylase: branched-chain aldolase/2- SP_RS04065 glucosidase: beta-ketoacyl- beta-ketoacyl- SP_RS00205 SP_RS00150 SP_RS00150 subunit alpha: ABC Macromolecule Modification protein: SP_RS09935 acyltransferase: SP_RS07640 alpha-keto acid unsaturated phosphorylase: triphosphate kinase/FMN N-acetylase: RS03770 alanine--tRNA glycine--tRNA ligase asparagine--tRNA threonine--tRNA isoleucine--tRNA glutamyl-tRNA arginine--tRNA tyrosine--tRNA aspartyl-tRNA histidine--tRNA tryptophan--tRNA leucine--tRNA proline--tRNA serine--tRNA ligase: valine--tRNA ligase: phenylalanine--tRNA ligase cysteine--tRNA lysine--tRNA ligase: methionine--tRNA methionine--tRNA 6-phosphate beta-D- keto-3-deoxy-6- purine-nucleoside SP_RS10225 ACP ACP beta-ketoacyl- hypothetical histidine histidine SP_RS05810 met transporter met DHAP (S)-lactaldehyde D-allopyranose pyruvate formate SP_RS08010 dehydrogenase chondroitin SP_RS04065 reductase: adenylyltransferase: SP_RS00715 ligase: SP_RS06780 subunit alpha: SP_RS07250 ligase: SP_RS07595 ligase: SP_RS08040 ligase: SP_RS08190 synthetase: SP_RS10450 ligase: SP_RS10585 ligase: SP_RS10695 synthetase: SP_RS11680 ligase: SP_RS10825 ligase: SP_RS11380 ligase: SP_RS01235 ligase: SP_RS01295 SP_RS02035 SP_RS02790 subunit alpha: SP_RS02865 ligase: SP_RS02925 SP_RS03490 ligase: SP_RS03850 ligase: SP_RS03850 tagatose-6- galactosidase: peptide phosphogluconate phosphorylase: [+ 4 isozymes] reductase: reductase: ACP protein: phosphatase phosphatase of L- D-allose superpathway of N-acetylglucosamine, lyase-activating subunit E2: disaccharide purine-nucleoside SP_RS00980 SP_RS05495 ribonucleoside- RS07335 queuosine biosynthesis phosphate SP_RS06515 deformylase: aldolase: SP_RS04085 a (3R)-3-SP_RS02080 a (3R)-3-SP_RS02080 a (3R,7Z,10reductase:Z a (3R,7Z)-3-SP_RS00205 family protein: family protein: methionine sucrose degradation IV (sucrose phosphorylase) kinase: N-acetylmannosamine and N- protein: SP_RS01190 α diphosphate kinase: 1-palmitoyl- SP_RS07155 SP_RS05730 hydrolase: phosphorylase: SP_RS01540 6-( -D- hydroxytetracosanoyl- hydroxydocosanoyl- ,13Z,16Z,19ZSP_RS02080)-3- hydroxytetradec- SP_RS04880 SP_RS04880 RS06355 Ala Gly Asn Thr Ile Glu Arg Tyr asp His Trp Leu Pro ser Val Phe Cys Lys Met Met Gln acetylneuraminate degradation β an L-alanyl-[tRNA ] a glycyl-[tRNA ] an L-asparaginyl-[tRNA ] an L-threonyl-[tRNA ] an L-isoleucyl-[tRNA ] an L-glutamyl-[tRNA ] an L-arginyl-[tRNA ] an L-tyrosyl-[tRNA ] an L-aspartyl-[tRNA ] an L-histidyl-[tRNA ] an L-tryptophanyl-[tRNA ] an L-leucyl-[tRNA ] an L-prolyl-[tRNA ] an L-seryl-[tRNA ] an L-valyl-[tRNA ] an L-phenylalanyl-[tRNA ] an L-cysteinyl-[tRNA ] an L-lysyl-[tRNA ] an L-methionyl-[elongator tRNA ] an L-methionyl-[initiator tRNA ] an L-glutaminyl-[tRNA ] SP_RS03280 acyl-carrier protein 2-myristoyl SP_RS01565 SP_RS04085 a 2'- roseoflavin acetate glucosaminyl)- -D-glucose a [protein]- a [protein]- reductase: RS04495 preQ SP_RS05855 aldehydo-D-allose a non 5-fluoro-5- MeOH [acp] [acp] hydroxydocosa- 7-enoyl-[acp] 0 N-acetylneuraminate a [formate C acetyltransferase]- phosphatidate D-galactopyranose deoxyribonucleoside adenine 6-phosphate L-histidine L-histidine SP_RS05815 D-tagatofuranose sucrose 6-phosphate 5'-deoxyadenosine galactosylated a [apo BCAA dehydrogenase 1-phosphatidyl- 7,10,13,16,19- 7-cyano-7- N-acetylneuraminate a flavodoxin semiquinone met a L-methionylaminoacyl- 6 dinucleotide deoxy-D-ribose glycin -2-yl radical galactose acceptor formate E2 protein] N -S-[3- 4-deoxy-L- N-acetyl-D- α-D-ribose- 5'-triphosphate glyoxylate pyruvate 1D-myo-inositol adenine pentaenoyl-[acp] GDP RS03140 deazaguanine 1,6-bisphosphate allose-6- lyase: SP_RS08280 tRNA 1-phosphate sucrose methylbutanoyl]dihydrolipoyl- threo-hex-4- glucosamine 1-phosphate RS05130 reductase: phosphate N-acetylneuraminate a purine base Polyprenyl Biosynthesis phosphorylase: L-lysine enopyranuronate 6-sulfate SP_RS08810 tagatose- isomerase: lyase: SP_RS06525 RS08100 preQ bisphosphate SP_RS09405 SP_RS05860 N-acetyl-D- , Carrier, and Vitamin Biosynthesis Metabolic Regulator 1 trans, trans-farnesyl aldolase: D-allulose 6- mannosamine RS01925 Biosynthesis tRNA α-D-glucopyranose a 2,3,4-saturated 2- 1-cis- 1-stearoyl- a 6-phospho- (4S)-4-hydroxy- phosphoenol a 3- a (5Z)-3- UDP diphosphate biosynthesis SP_RS12145 β-D-fructofuranose phosphate N-acetylmannosamine a 2,3,4-saturated a cis- sn-glycerol arsenate α a uracil in DNA a nucleoside a 3-oxohexacosanoyl- a 3-oxotetradecanoyl- RS06215 [2Fe-2S] iron-sulfur cluster biosynthesis guanosine(34) 1-phosphate lysophosphatidate vaccenoylglycerol- sn-glycerol a palmitoyl-[acp] a stearoyl-[acp] a purine β-D-galactoside -D- MEP 2-oxoglutarate RNA oxodocosanoyl- a protein oxotetracos- ser a tRNA sec flavin biosynthesis I (bacteria and plants) superpathway of tetrahydrofolate biosynthesis thiamine salvage III superpathway of heme tagatose 1,6- kinase: SP_RS08275 fatty acyl-[acp] vaccenoyl-[acp] 3-phosphate ATP CTP dGDP pyruvate triphosphate [acp] [acp] ribonucleoside- dADP thiamine formation from pyrithiamine and oxythiamine (yeast) NAD biosynthesis ppGpp biosynthesis transglycosylase allulose-6- 3-phosphate 3-phosphate ribonucleoside glucopyranose hypothetical hypothetical [acp] hypothetical 5-enoyl-[acp]hypothetical RS03380 I (from aspartate) b biosynthesis from IPP diphosphate phosphoglucomutase: phosphate 3- N-acetyl-D- 1-phosphate diphosphate ribonucleoside- uroporphyrinogen-III Tgt: SP_RS10405 fructokinase: SP_RS07375 mannosamine 6-phospho-beta- protein: protein: protein: protein: reductase L-cysteine desulfurase thiamine isopentenyl- a 7-aminomethyl-7- aldolase: epimerase: 1-acyl-sn-glycerol- bifunctional 2-keto- uracil-DNA diphosphate RS09265 thiamine RS03540 thiamine pyrithiamine pppGpp SP_RS08515 6-phosphate 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- glycerol-3- purine-nucleoside galactosidase: 2-C-methyl-D- DNA- SP_RS00205 SP_RS00205 SP_RS00205 Xaa-Pro SP_RS00205 subunit alpha: serine-- GTP GTP thiamine asp uroporphyrinogen-III diphosphate deazaguanosine 34 SP_RS05850 chitobiose degradation D-glucopyranose SP_RS07970 3-phosphate 4-hydroxyglutarate pyruvate glycosylase: reductase GTP pyrophosphokinase: ∆ N-acetylmannosamine- 3-phosphate 3-phosphate phosphate phosphorylase: SP_RS02355 glucose-1-phosphate erythritol 4-phosphate directed RNA beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- dipeptidyl- beta-ketoacyl- SP_RS05810 tRNA ligase: cysteine pyrophosphokinase: thiaminase II: -isomerase: in tRNA 6-phosphate acyltransferase: aldolase/2- kinase: SP_RS03060 subunit alpha: SP_RS08110 D-glyceraldehyde F6P 6-phosphate acyltransferase: acyltransferase: acyltransferase: SP_RS04065 6-phospho-beta- adenylyltransferase: cytidylyltransferase: polymerase ACP ACP ACP peptidase: ACP SP_RS02035 RS02660 desulfurase: bifunctional GTP SP_RS09960 SP_RS03535 SP_RS01885 tRNA preQ1(34) S- N,N'- SP_RS08010 keto-3-deoxy-6- SP_RS04425 uracil-DNA ribonucleoside- SP_RS05810 RS05010 thiamine GTP pyrophosphokinase: guanosine 3'-diphosphate DMAPP DHAP 3-phosphate glucose-6- 2-epimerase: SP_RS08010 SP_RS08010 SP_RS04175 purine-nucleoside galactosidase: SP_RS05555 SP_RS06230 subunit omega: reductase: reductase: reductase: SP_RS04410 reductase: SP_RS04280 3,4-dihydroxy- cyclohydrolase adenosylmethionine diacetylchitobiose phosphogluconate glycosylase: diphosphate diphosphate 2-iminosuccinate coproporphyrinogen III SP_RS05430 5'-triphosphate 3'- phosphate SP_RS08325 phosphorylase: SP_RS05825 glucose-1-phosphate SP_RS08595 SP_RS02080 SP_RS02080 SP_RS02080 SP_RS02080 ribonucleoside- RS04600 [+ 2 isozymes] 2-butanone- I FolE: 4-amino-2-methyl-5-pyrimidinemethanol ribosyltransferase- 6'-phosphate a 2,3,4-saturated aldolase: SP_RS05765 a (3R)-3- a (3R)-3- a (3R)-3- a (3R,5Z)-3- reductase: an L-seryl- diphosphatase: geranyl isomerase: pgi 1,2-dicis- 1-stearoyl- 1-stearoyl- SP_RS04085 adenylyltransferase 4-(cytidine 5'- [+ 6 isozymes] diphosphate 4-phosphate N-acetylmannosamine- 1,2-diacyl-sn acyl-carrier protein SP_RS01540 pyruvate hydroxyhexacosanoyl- hydroxytetradecanoyl- hydroxydocosanoyl- hydroxytetracos- SP_RS05815 [tRNA sec ] an S-sulfanyl-[L- SP_RS01430 SP_RS08110 diphosphate isomerase QueA: vaccenoyl- 2-palmitoyl- sn-glycerol subunit GlgD: diphospho) a dipeptide reductase: synthase/GTP 7,8- hydroxymethylpyrimidine/ F6P acetoin degradation 6-phosphate -glycerol 3- acyl-carrier protein acyl-carrier protein acyl-carrier protein D-galactopyranose dGTP [acp] [acp] [acp] a peptide 5-enoyl-[acp] cysteine desulfurase] synthase: SP_RS06940 phosphatidate sn-glycerol 3-phosphate SP_RS05560 -2-C-methyl- an apyrimidinic uracil dUDP SP_RS05815 RS10690 RS09890 cyclohydrolase dihydroneopterin phosphomethylpyrimidine 2-O-α-mannosyl- 2-epimerase: phosphate ribose-1-arsenate an alcohol 6-phosphate scaffold kinase: SP_RS07875 SP_RS05920 an epoxyqueuosine 34 N-monoacetylchitobiose 3-phosphate a purine base D-erythritol site in DNA RNA ADP II: SP_RS00875 3'-triphosphate quinolinate protoporphyrinogen IX GTP ppGpp D-glycerate SP_RS06530 glyoxylate pyruvate RS08800 protein for iron- in tRNA 6'-phosphate acetoin coenzyme A N-acetyl-D- 2,5-diamino-6- bifunctional geranyl degradation ADP-α-D-glucose sulfur cluster (5-phospho-D- hydroxymethylpyrimidine nicotinate- diphosphate 2-O-(6-phospho- glucosamine α-D-mannosyl) 6-phospho- RS08610 assembly: ribosylamino) kinase/ nucleotide GTP pyrophosphokinase: trehalose degradation TPP-dependent 6-phosphate RS05605 SP_RS04285 7,8- geranyltranstransferase: -D-glyceratealpha- beta- I (low osmolarity) N-acetylglucosamine- pyrimidin- diphosphorylase 34 γ 516 dihydroneopterin phosphomethylpyrimidine SP_RS08110 SP_RS05920 a queuosine acetoin 1-stearoyl- 1-stearoyl- a reduced (1S,2R)-1- salicin 6- L-alanyl- -D- a uridine phosphoenol a [protein]-L- an (11Z)-3- dCDP RS11435 an S-sulfanyl-[cysteine 4(3H)-one (carboxylating) protoporphyrin IX mannosidase: glucosidase: 6-phosphate an acyl-[acyl- 1-myristoylglycerol KDGP a tetrahydrofolate H O a ribonucleoside a 3-oxohexadecanoyl- a 3-oxooctadecanoyl- a 3-oxoicosanoyl- a nucleoside kinase: SP_RS03555 GTP pyrophosphokinase: guanosine-3',5'- in tRNA α,α-trehalose dehydrogenase sn-glycerol a myristoyl-[acp] sn-glycerol a stearoyl-[acp] + + ferredoxin [iron- ser C-(indol-3- 2 glutamyl-meso-2,6- ω oxooctadec- desulfurase]-[disordered- 3'-phosphate SP_RS10935 SP_RS10225 deacetylase: carrier protein] 3-phosphate NADP H phosphate in 16S rRNA dADP pyruvate diphosphate [acp] [acp] [acp] proline ( = 180) ribonucleoside- diphosphate dIDP bifunctional : SP_RS10205 UDP kinase: SP_RS04800 SP_RS05430 bis(diphosphate) (2E,6E)-farnesyl 6-phosphate complex, 3-phosphate 3-phosphate sulfur] cluster yl)glycerol diaminopimeloyl- 16S rRNA ribonucleoside- hypothetical hypothetical hypothetical peptidyl-prolyl 11-enoyl-[acp]hypothetical nucleoside- form scaffold HMP-P ferrochelatase: D-glycerate [+ 4 isozymes] SP_RS10395 diphosphate UDP kinase: RS00535 diaminohydroxyphosphoribosylaminopyrimidine oxythiamine nucleoside-diphosphate 3'-diphosphatase: diphosphate E1 protein 3-phosphate D-alanine pseudouridine(516) diphosphate protein: protein: protein: cis-trans protein: diphosphate RS00565 protein] complex deaminase/5-amino-6-(5-phosphoribosylamino) NaMN SP_RS05005 D-glucosamine gamma-glutamyl 6-phospho- reductase SP_RS04800 cysteine hydroxymethylpyrimidine/ kinase: SP_RS09845 SP_RS08110 glycerate N-acetyl-D- alpha,alpha- subunit beta: 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- ferredoxin- bifunctional 2-keto- synthase: reductase SP_RS00205 SP_RS00205 SP_RS00205 isomerase: SP_RS00205 kinase: uracil reductase: SP_RS00885 7,8- D-glucosamine 6-phosphate tryptophan hydrolase: beta- subunit alpha: nucleoside- RS02475 desulfurase: thiaminase II: phosphomethylpyrimidine nicotinate-nicotinamide GDP lipoprotein posttranslational 2-kinase: glucosamine phosphotrehalase: SP_RS05735 3-phosphate 3-phosphate 3-phosphate -NADP(+) 4-hydroxyglutarate LD- SP_RS01370 pyruvate subunit alpha: beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- SP_RS07575 beta-ketoacyl- SP_RS09845 5-amino-6-(5- dihydroneopterin ferroheme b synthase SP_RS10555 glucosidase: SP_RS05810 diphosphate SP_RS04280 SP_RS03535 kinase: SP_RS07875 nucleotide modification SP_RS05580 6-phosphate SP_RS09345 acyltransferase: acyltransferase: acyltransferase: reductase: aldolase/2- carboxypeptidase: 16S rRNA kinase: SP_RS05810 ACP ACP ACP peptidyl-prolyl ACP UDP kinase: phospho-D- subunit beta: gamma-glutamyl SP_RS10225 ribonucleoside- kinase: RS02580 [+ 2 isozymes] bifunctional dihydroneopterin adenylyltransferase: 2-phospho- SP_RS08010 SP_RS08010 SP_RS08010 SP_RS07705 keto-3-deoxy-6- SP_RS00905 pseudouridine(516) SP_RS04425 reductase: reductase: reductase: cis-trans reductase: SP_RS04800 a [cysteine desulfurase]- D-ribulose ribosylamino)uracil aldolase/2-amino-4-hydroxy-6- 5-(2-hydroxyethyl)-4-methylthiazole bifunctional NAD phosphorylation a [prolipoprotein]- acetaldehyde acetyl-CoA phosphogluconate SP_RS08995 hydrolase: [+ 4 isozymes] ribonucleoside- diphosphate a nucleoside SP_RS09845 RS03700 bifunctional nadD D-glycerate glucokinase: α-D-glucosamine synthase: SP_RS02080 SP_RS02080 SP_RS02080 isomerase: SP_RS02080 S-sulfanyl-[disordered- 5-phosphate chorismate hydroxymethylpyrimidine 10 and dephosphorylation L-cysteine diphosphate a (3R)-3- a (3R)-3- a (3R)-3- a (3R,11Z)-3- hydroxymethyldihydropteridine N -formyl-tetrahydrofolate biosynthesis lactose aldolase: SP_RS05395 γ SP_RS03340 SP_RS03765 reductase: triphosphate dITP RS02115 diaminohydroxyphosphoribosylaminopyrimidine hydroxyethylthiazole kinase/ nicotinate adenine D-glucopyranose SP_RS03280 6-phosphate a 1-stearoyl 2- dimyristoyl 1-stearoyl-2- an oxidized D-glyceraldehyde L-alanyl- -D- reductase: hydroxyhexadecanoyl- hydroxyoctadecanoyl- hydroxyicosanoyl- hydroxyoctadec- form scaffold bifunctional diphosphokinase: SP_RS01435 prolipoprotein D-mannose D-glucopyranose degradation III acyl-carrier protein SP_RS01540 β-D-glucose a 16S rRNA pyruvate a [protein]-L- SP_RS05815 deaminase/5-amino-6-(5-phosphoribosylamino) aminodeoxychorismate kinase: SP_RS03510 phosphomethylpyrimidine dinucleotide NAD + glucosamine- acyl-sn-glycerol acyl-carrier protein phosphatidate acyl-carrier protein stearoyl-sn ferredoxin [iron- trp D-ala glutamyl-meso- dATP SP_RS05815 protein] complex 3,4-dihydroxy- diacylglyceryl degradation 6-phosphate NADPH 3-phosphate salicyl alcohol pseudouridine 516 a 2'- [acp] [acp] [acp] proline (ω = 0) 11-enoyl-[acp] 6-(hydroxymethyl) synthase, component 6-phosphate CDP + + RS10440 cysteine uracil reductase: SP_RS00885 [+ 2 isozymes] kinase: SP_RS03555 NAD+ a tetrahydrofolate transferase: lactose 6-phosphate 3-phosphate -glycerol 3- sulfur] cluster diaminopimelate deoxyribonucleoside H RS07435 H 2-butanone- 5-amino-6-(5- -7,8-dihydropterin I: SP_RS03265 D-mannopyranose melibiose degradation phosphate Glu desulfurase: 4-methyl-5-(2- synthetase, NAD(+) Cell Structure Biosynthesis SP_RS06920 beta-D- deaminase: D-glyceraldehyde 5'-diphosphate 4-phosphate phospho-D- bifunctional dihydroneopterin HMP-PP acid 6-phosphate pyruvate RS06775 SP_RS04280 4-amino-4- phosphonooxyethyl)thiazole glutamine synthetase: NAD(+) kinase: a [prolipoprotein]- mannose-6- galactosidase: SP_RS06935 3-phosphate synthase/GTP ribitylamino)uracil aldolase/2-amino-4-hydroxy-6- phosphatase: [+ 2 isozymes] deoxychorismate dependent: SP_RS06965 SP_RS05435 (S-diacylglyceryl) phosphate fructose degradation melibiose SP_RS08355 RS09775 an S-sulfanyl-[cysteine cyclohydrolase L-cysteine biosynthesis hydroxymethyldihydropteridine SP_RS09640 peptidoglycan biosynthesis F6P RS10880 aminodeoxychorismate thiamine phosphate SP_RS06965 β peptidoglycan cross-bridge -L-cysteine isomerase: beta-D- desulfurase]-S- II: SP_RS00875 VI (from L-methionine) diphosphokinase: SP_RS01435 V ( -lactam resistance) 1-cis- 1-stearoyl- D-cellobiose UDP-N-acetylmuramoyl- 3'-dephospho- arbutin-6- a dipetide with an N- an N-terminal- a (6Z)-3- a (5Z)-3- lyase: SP_RS07475 synthase: SP_RS03515 thiamine salvage IV (yeast) biosynthesis IV (Weissella viridescens) SP_RS03605 β-D-fructofuranose alpha-galactosidase: galactosidase: 1-palmitoylglycerol an unsulfurated a [protein] Ser/Thr a 3-oxoglutaryl- a 3-oxohexanoyl- carbonic acid sulfanyl-[disordered- 1-deoxy-L- + UDP-N-acetyl- vaccenoylglycerol- a palmitoleoyl-[acp] a palmitoyl-[acp] sn-glycerol an oleoyl-[acp] L-alanyl-γ-D- cys H O L-cystathionine L-methionyl-L- an acetoacetyl-[acp] oxooctadec- oxododec- (7,8-dihydropterin- NAD UDP-N-acetyl-α-D-muramoyl- signal F6P 1-phosphate 3-phosphate 6'-phosphate [sulfur carrier] ATP CoA phosphate 2 GTP terminal L-aspartate [acp] methyl ester [acp] IDP RS07755 form scaffold glycero-tetrulose thiamine phosphate dihydrofolate NADP + α-D-glucosamine SP_RS09430 SP_RS06515 3-phosphate 3-phosphate glutamyl-meso-2,6- serine/threonine valyl-[protein] 6-enoyl-[acp] 5-enoyl-[acp] ARP met 6-yl)methyl 4-aminobenzoate L-alanyl-γ-D-glutamyl-L- peptidase II: 1-phosphofructokinase: β hypothetical hypothetical hypothetical hypothetical beta-ketoacyl- protein] complex 4-phosphate thiamine salvage II synthase: SP_RS03550 thiamine reductase: -D-galactose diaminopimeloyl- protein kinase: UDP kinase: RS07530 cysteine S-adenosylmethionine diphosphate UDP-N-acetylglucosamine lysyl-D-alanyl-D-alanineUDP-N- SP_RS04590 β SP_RS04320 protein: protein: protein: protein: ACP carbonate RS00260 SP_RS07745 -D-fructose 1,6- D-galactopyranose D-glucopyranose 1-acyl-sn-glycerol- 6-phospho- D-alanine 6-phospho- SP_RS08570 dipeptidase: SP_RS04800 desulfurase: synthase: 4-amino-2-methyl-5- 1-carboxyvinyltransferase: acetylmuramoylpentapeptide- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- cysteine GTPase A: cystathionine methionine SP_RS00205 SP_RS00205 SP_RS00205 SP_RS00205 reductase: dehydratase: 6,7-dimethyl-8- dihydropteroate gcv system: an (S-diacyl- bisphosphate 3-phosphate beta- dephospho- beta- HPr kinase/ SP_RS07840 nucleoside- SP_RS04280 SP_RS03725 pyrimidinemethanol thiamine phosphate thiaminase II: a 7,8-dihydrofolate a 5-methyltetrahydrofolate SP_RS09880 lysine N(6)-alanyltransferase: a lipoprotein 3-phosphate 3-phosphate desulfurase: SP_RS09970 beta-lyase: aminopeptidase: beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- SP_RS02080 SP_RS00160 ribityllumazine synthase: SP_RS05725 sn-glyceryl) acyltransferase: glucosidase: CoA kinase: glucosidase: phosphorylase: dipeptidase diphosphate RS04075 [+ 2 isozymes] SAM SP_RS03535 serine UDP-N-acetylglucosamine UDP-N-acetyl-α-D-muramoyl-SP_RS03020 signal peptide acyltransferase: acyltransferase: LD- SP_RS05415 [+ 3 isozymes] SP_RS03305 SP_RS05360 ACP ACP ACP ACP hypothetical a [cysteine synthase: SP_RS01420 hydroxymethylpyrimidine/ -L-cysteinyl- SP_RS08010 SP_RS10225 SP_RS04815 SP_RS10225 SP_RS06925 PepV: kinase: hydroxymethyltransferase: glyA 1-carboxyvinyltransferase: L-alanyl-γ-D-glutamyl-N 6 -(L- SP_RS08010 SP_RS08010 carboxypeptidase: [+ 2 isozymes] reductase: reductase: reductase: reductase: protein: RS10805 desulfurase]-(S- SP_RS00870 phosphomethylpyrimidine [apolipoprotein] [+ 4 isozymes] [+ 4 isozymes] a [protein] (L-serine/L- SP_RS03055 SP_RS09845 RS06010 4-amino-2-methyl-5- 5-(2-hydroxyethyl)-4-methylthiazole thymidylate SP_RS05345 alanyl)-L-lysyl-D-alanyl-D-alanine SP_RS00905 an N-terminal SP_RS02080 SP_RS02080 SP_RS02080 SP_RS02080 SP_RS00205 CO H O sulfanyl) -[disordered- 7,8- kinase: SP_RS07875 Detoxification H + threonine) phosphate a (3R)-3- a (3R)-3- a (3R)-3- a (3R,6Z)-3- a (3R,5Z)-3- 2 2 2 pyrimidinemethanol synthase: α 1-cis-vaccenoyl- dipalmitoyl 1-stearoyl-2- phosphate L-homocysteine pyruvate met ITP UDP-N-acetyl- - + GDP L-valyl-[protein] hydroxybutanoyl- hydroxyglutaryl- hydroxyhexanoyl- hydroxyoctadec- hydroxydodec- form scaffold 6,7-dimethyl-8-(1- dihydropteroate bifunctional a (6S)-5- acyl-carrier protein D-glucopyranose a sulfurated coenzyme A H β-D-glucose hydroxymethylpyrimidine/ hydroxyethylthiazole SP_RS03285 D-glucosamine- acyl-carrier protein 2-palmitoleoyl phosphatidate acyl-carrier protein oleoyl-sn-glycerol D-glucopyranose UDP-N-acetyl-α-D- ala ADP hydroquinone a proteinogenic [acp] [acp] methyl ester [acp] 6-enoyl-[acp] 5-enoyl-[acp] RS00985 protein] complex D-ribityl)lumazine dihydrofolate hydroxymethylpyrimidine bifunctional formyltetrahydrofolate a peptide oxidized GTP and 6-phosphate [sulfur carrier] 6-phosphate asp SAH phosphomethylpyrimidine kinase: SP_RS03510 enolpyruvate an N-acyl-(S- arsenate reactive oxygen phosphatidate 3-phosphate D-ala muramoyl-L-alanyl- amino acid RS06405 riboflavin synthase: kinase/ methylenetetrahydrofolate UDP-N-acetylmuramoyl-L-alanyl- dGTP detoxification kinase: SP_RS07875 [+ 2 isozymes] methylenetetrahydrofolate 5-formyltetrahydrofolate 6 diacyl-sn-glyceryl) detoxification γ-D-glutamyl-meso- RS07340 synthase: phosphomethylpyrimidine UDP-N- D-glutamyl-N -(L-alanyl-L- species degradation SP_RS00955 reductase [NAD(P) dehydrogenase/ cyclo-ligase: -L-cysteinyl- II (glutaredoxin) 2,6-diaminopimelate SP_RS00880 5'-methylthioadenosine/ kinase: SP_RS03555 bifunctional 4-methyl-5-(2- acetylenolpyruvoylglucosamine seryl)-L-lysyl-D-alanyl-D-alanine a [cysteine desulfurase]- S-adenosylhomocysteine dihydrofolate hydroxymethylpyrimidine phosphonooxyethyl)thiazole H]: SP_RS02905 methenyltetrahydrofolate SP_RS10670 reductase: SP_RS06785 [lipoprotein] superoxide cyclohydrolase: SP_RS04035 dGTP GTP arsenate RS01800 [scaffold protein- riboflavin nucleosidase: synthase: kinase/ thiamine phosphate a 5,10- a 5,10- L-ascorbate Carboxylate Degradation HMP-P UDP-N- arsenate a [DNA]-3'- a 5'-phospho- 3-benzyl-3,6-dihydroxy- a [ThiI sulfur- a guanine 34 N-acetyl-D- a 3- a (7Z)-3-oxo- a (9Z)-3- RS00495 (2Fe-2S)] complex SP_RS01425 ketogluconate metabolism superoxide dismutase: sn-glycerol 1-palmitoylglycerol a cis- + lysine within ADP-D-ribose a 3-oxopimeloyl- a cis-delta11-3- acetylxylan SP_RS04915 phosphomethylpyrimidine synthase: methylenetetrahydrofolate methenyltetrahydrofolate acetylenolpyruvoylglucosamine degradation I reductase: a palmitoyl-[acp] NAD 6-(hydroxymethyl) queuine glycerophosphoserine galactosamine H O (R)-lipoate oxododecanoyl- hexadec-7- oxooctacos- cys RS00425 bifunctional riboflavin SP_RS10385 3-phosphate 3-phosphate vaccenoyl-[acp] hydroxyl [DNA] glutathione cys carrier protein]- in tRNA 2 ATP phe gcv protein H ATP [acp] methyl ester oxo-C30:1-[acp] S-ribosyl-L- 7,8-dihydrofolate hydroxymethylpyrimidine/ kinase: SP_RS03555 SP_RS03515 bifunctional reductase: SP_RS06815 (bacterial, anaerobic) SP_RS00930 -diketopiperazine 6-phosphate [acp] enoyl-[acp] 9-enoyl-[acp] 6 37 8-oxo-dGTP 8-oxo-GTP L-cysteine ammonium CO hypothetical hypothetical beta-ketoacyl- hypothetical hypothetical lanthionine kinase/FMN monoglutamate phosphomethylpyrimidine N -L-threonylcarbamoyladenosine L-ascorbate 2,5-didehydro- superoxide dismutase aspartate 2 homocysteine thiamine phosphate methylenetetrahydrofolate ala UDP-N-acetyl- arsenate protein: protein: protein: protein: synthetase: adenylyltransferase: kinase: SP_RS07875 HMP-P -modified tRNA biosynthesis 6-phosphate D-gluconate [Mn]: SP_RS03740 DNA tRNA glycerophosphoryl aminotransferase: lipoate--protein ADP-ribose ACP acetylxylan RS01845 a [co-chaperone]- 5-(2-hydroxyethyl) synthase: dehydrogenase/ α-D-muramate L-ascorbate- 8-oxo-dGTP reductase glycerol-3- 1-acyl-sn-glycerol- glutathione S- SP_RS00205 SP_RS00205 SP_RS00205 SP_RS00205 SP_RS01860 RS10570 SP_RS05495 S-ribosylhomocysteine ligase cysteine guanosine(34) diester N-acetylglucosamine- ATPase: SP_RS07605 ligase A: pyrophosphatase: reductase: : [scaffold protein- bifunctional -4-methylthiazole hydroxymethylpyrimidine/ SP_RS03550 thiamine diphosphate heme b biosynthesis methenyltetrahydrofolate 6-phosphate pyruvate fermentation diphosphatase: family protein: hydrogen peroxide phosphate 3-phosphate transferase: carbamate lyase: SP_RS01655 2,5-diketo-D- (NAD(+)) desulfurase: transglycosylase : 6-phosphate SP_RS07650 aspartate SP_RS05720 SP_RS04905 beta-ketoacyl- beta-ketoacyl- SP_RS02080 beta-ketoacyl- beta-ketoacyl- SP_RS08380 lanthionine RS04135 (2Fe-2S)] complex FMN hydroxymethylpyrimidine phosphomethylpyrimidine biosynthesis I (E. coli) II (anaerobic) cyclohydrolase: SP_RS04035 UDP-N- Glu thr lactonase: to acetate IV SP_RS05760 SP_RS07185 acyltransferase: acyltransferase: SP_RS07645 kinase: SSQ1 S-ribosylhomocysteinase: hydroxyethylthiazole gluconic acid LigA: ligA SP_RS05415 Tgt: SP_RS10405 SP_RS04930 deacetylase: [+ 2 isozymes] aminotransferase: ACP ACP hypothetical ACP ACP synthetase: a 7,8-dihydrofolate kinase/ kinase: SP_RS07875 thiamine phosphate 2-[(2R,5Z)- an N 10 - acetylmuramate-- threonylcarbamoyl-AMP SP_RS10270 8-oxo-GMP arsenite SP_RS04175 SP_RS08010 SP_RS10965 serine serine chaperone: SP_RS11685 kinase: SP_RS03510 glutamate reductase: 7,8-dihydro-8- [+ 2 isozymes] SP_RS10395 SP_RS08935 D-ribofuranose reductase: reductase: protein: reductase: reductase: SP_RS06595 RS09795 RS08675 bifunctional riboflavin phosphomethylpyrimidine 2-carboxy-4- uroporphyrinogen-III formyltetrahydrofolate L-alanine ligase: synthase: SP_RS05075 2-keto-L-gulonate pyruvate a [glycine-cleavage acetate xylan thr thr [+ 2 isozymes] bifunctional L-ascorbate- SP_RS07260 oxoguanine 3-benzyl-3,6 -bis(glutathione) 2-oxo-3- 6 SP_RS02080 SP_RS02080 SP_RS00205 SP_RS02080 SP_RS02080 SP_RS02530 kinase/FMN dihydrofolate racemase: 34 + complex H protein] N 5-phosphate a (3R)-3- a (3R)-3- a (3R,7Z)-3- a cis-delta11-3- a cis-delta9-3- lanthionine L-homocysteine kinase: SP_RS03555 4-methyl-5-(2- methylthiazol-5(2H SP_RS07490 L-threonylcarbamoyladenylate triphosphatase: 1-palmitoyl-2- - 6-(hydroxymethyl) a queuosine sn-glycerol phosphate H phenylpropanoate AMP a [chaperone-ATP]- adenylyltransferase: reductase: hydroxymethylpyrimidine SP_RS09330 6-phosphate 1-palmitoylglycerol [DNA] NMN a [ThiI sulfur- D-galactosamine ADP -[(R)-lipoyl]-L-lysine carbamoyl hydroxydodecanoyl- hydroxypimeloyl- hydroxy-hexadec- hydroxyC30:1- hydroxyC28:1- phosphonooxyethyl) )-ylidene]ethyl SP_RS06055 acyl-carrier protein acyl-carrier protein cis-vaccenoyl AMP -diketopiperazine guanine in tRNA 3-phosphate ser acetate RS00790 [co-chaperone]- SP_RS07745 HMP-PP kinase/ HMP-PP UDP-N-acetyl- N 6 -L- lactonase: 2-keto-D- formate C- O H O hydroxyl radical 3-phosphate ala carrier protein]- 6-phosphate phosphate [acp] [acp] methyl ester 7-enoyl-[acp] [acp] [acp] SP_RS05495 phosphate 2 2 phosphatidate RS11320 [scaffold protein- thiazole phosphomethylpyrimidine coproporphyrinogen III α D-glt SP_RS10275 gluconate acetyltransferase/ S-sulfanyl- thiamine -D-muramoyl- threonylcarbamoyladenine 3-keto-L-gulonate 8-oxo-dGMP arsenite RS03100 (2Fe-2S)] complex FAD a tetrahydrofolate kinase: SP_RS03555 lipoate salvage I L-alanine synthase: SP_RS00655 L-idonate glycerol L-cysteine thiamine thiamine coproporphyrinogen 6-phosphate thiamine 6 dehydratase phosphate HMP-PP phosphate III dehydrogenase: an N -L- SSQ1 L-cystathionine pyrophosphokinase: UDP-N- 37 3-keto-L- L-idonate 5- family glycyl RS06760 synthase: SP_RS06905 (R)-lipoate threonylcarbamoyladenine in tRNA an [HPr]- phosphoenol an N-terminal- an N-terminal- a peptide with RS08710 chaperone synthase: SP_RS09960 acetylmuramoyl- gulonate-6- dehydrogenase: radical : Secondary 1-myristoylglycerol sn-glycerol F6P a D-aminoacyl- a peptide with a FMN NAD(P)H H + stachyose palmitoyl-CoA H O a 3-oxodecanoyl- a cis-delta15-3- an L-cysteinyl- a palmitoleoyl-[acp] a myristoyl-[acp] L-methionyl-L- a RNA-DNA hybrid a type IV prepilin 2 L-methionyl- an N-terminal ser SP_RS03515 SP_RS03515 lipoate--protein SP_RS01400 3-phosphate L-histidine pyruvate 3-phosphate ATP [tRNA] [tRNA Cys ] IMP ATPase: protoporphyrinogen IX L-alanine--D- phosphate SP_RS01220 Metabolite a tRNA precursor leader sequence cysteinyl-[protein] glycyl-[protein] L-methionine [acp] oxo-C34:1-[acp] S-adenosyl-L-methionine cycle I thiamine diphosphate thiamine ligase A: hypothetical hypothetical L-serine SP_RS02530 glutathione- thiamine glutamate ligase: decarboxylase: 5-dehydro- formate Degradation CTP guanosine phosphate SP_RS05720 alpha- protein: protein: dehydratase, glutaredoxin phosphate thioredoxin SP_RS03370 ulaD D-gluconate acetyltransferase: mannitol phosphoenolpyruvate- fructose-6- HII: flavin acyl-CoA monophosphate a [chaperone- di-trans,poly-cis-undecaprenyl synthase: lipoyl-adenylate 1-acyl-sn-glycerol- glycerol-3- D-aminoacyl- signal methionine galactosidase: prepilin methionine methionine SP_RS00205 SP_RS00205 peptidyl-tRNA iron-sulfur- RS06790 RS09760 an [2Fe-2S] redox reactions cys SAM synthase: pathway L-xylulose SP_RS02265 degradation I -protein phosphate CCA-adding SP_RS05705 reductase: thioester reductase: ADP]-[disordered- phosphate biosynthesis SP_RS03550 UDP-N-acetyl- Glycolysis 3-phosphate phosphate tRNA peptidase I: aminopeptidase: SP_RS09430 peptidase: aminopeptidase: aminopeptidase: beta-ketoacyl- beta-ketoacyl- hydrolase: dependent cluster protein SP_RS03550 lipoate--protein 5-phosphate gluconate 5- phosphotransferase: aldolase: enzyme: ribonuclease HII: SP_RS02775 hydrolase: SP_RS06125 form scaffold GSSG protoporphyrin IX lys α-D-muramoyl-L- D-mannitol acyltransferase: acyltransferase: deacylase: SP_RS01995 SP_RS05360 SP_RS08975 SP_RS05360 SP_RS05360 ACP ACP SP_RS00025 subunit beta: (2E,6E)-farnesyl an oxidized ligase A: dehydrogenase: SP_RS05795 SP_RS01225 SP_RS07665 SP_RS05710 SP_RS03270 protein] complex glutathione- S-adenosylmethionine alanyl-D-glutamate L-xylulose 5- acetyl-CoA formate 1-phosphate SP_RS08010 SP_RS04175 SP_RS08105 reductase: reductase: GMP SP_RS00540 disulfide thiamine diphosphate thioredoxin lipoate biosynthesis thiamine SP_RS05720 glycolysis III (from glucose) phosphate 3- SP_RS01555 mannitol-1- α-D-galactose raffinose synthase: SP_RS03725 di-trans,poly-cis-decaprenyl ferrochelatase: a [lipoyl-carrier FMNH NAD(P) + SP_RS02080 SP_RS02080 pyruvate phosphate and incorporation II phosphate phosphate 5- an [HPr protein]- an N-terminal L- 2 an N-terminal a (3R)-3- a cis-delta15-3- RS10700 RS08820 reductase: epimerase: phosphate 1-myristoyl-2- D-glyceraldehyde a tRNA a cleaved type Cys non- diphosphate:isopentenyl- SP_RS05005 protein]-N 6 -[(R UDP-N- π pyruvate 1-myristoylglycerol dihydroxyacetone a leader sequence a peptide met cysteinyl-[protein] DNA a nucleoside 5'- a peptide palmitate met glycyl-[protein] met a peptide cys a tRNA SP_RS03830 thiamine thiamine D-glucopyranose SP_RS10285 D-gluconate acetyltransferase: dehydrogenase: palmitoleoyl N -phospho- 3-phosphate containing a an uncharged IV prepilin hydroxydecanoyl- hydroxyC34:1- chaperonin met SAH diphosphate )-lipoyl]-L-lysine acetylmuramoyl- acyl-carrier protein acyl-carrier protein 3-phosphate a D-amino acid monophosphate glutathione monophosphate thioredoxin- octanoate monophosphate ferroheme b L-ribulose 5- SP_RS05445 SP_RS01970 phosphatidate L-histidine 3' CCA end tRNA [acp] [acp] molecular undecaprenylcistransferase: lipoate--protein L-alanyl-D- glucokinase: 5'-methylthioadenosine/ kinase: disulfide kinase: base-degraded D-ala phosphate D-gluconate pyruvate decarboxylation to acetyl CoA F6P chaperone di-trans,octa-cisSP_RS01280 ligase A: glutamate--L- SP_RS03280 RS05695 S-adenosylhomocysteine SP_RS03550 reductase: SP_RS03550 thiamine salvage kinase: acetyl phosphate RS01830 ATPase: -undecaprenyl SP_RS05720 lysine ligase: L-ribulose-5- γ 5-methyltetrahydropteroyltriglutamate- nucleosidase: SP_RS04915 SP_RS07165 a [lipoyl-carrier D-alanine- D-glucopyranose SP_RS11165 a [pyruvate dehydrogenase a 2-acetyl-1-alkyl- RNase III mRNA an (S)-2- an N-terminal- 1-cis- -L-glutamyl-(S)- a peptide with a (3R,5Z)-3- a [protein]-L- a [protein]- SP_RS02530 thiamine diphosphate 6 thiamine formylaminopyrimidine SP_RS07535 phosphate 4- 1-palmitoylglycerol sn-glycerol a cis- L-aspartate- glycerophosphoglycerol an N-modified raffinose a peptidoglycan a cis-delta17-3- acetyl-CoA - homocysteine protein] N - -D-alanine 6-phosphate D-gluconate 6 a palmitoleoyl-[acp] sn-glycero-3- processing L-methionyl-L- vaccenoylglycerol- trans-1-propenyl- L-saccharopine an N-terminal hydroxy-tetradec- undecaprenyl- diphosphate epimerase: acetate kinase: E2 protein] N -lipoyl-L-lysine 3-phosphate 3-phosphate vaccenoyl-[acp] pyruvate aminoacyl-[tRNA] halocarboxylate oxo-C36:1-[acp] methionine L-tyrosine a reduced methyltransferase: SP_RS02900 diphosphate octanoyl-L-lysine ligase A: 6-phosphate phosphocholine substrate semialdehyde threonyl-[protein] 3-phosphate L-cysteine L-alanine 5-enoyl-[acp] acetyl-CoA peptide- tyrosine- a [disordered- an [Fe-S cluster glutaredoxin L-homocysteine S-ribosyl-L-homocysteine diphosphatase: UDP-N-acetyl- glucose-6- SP_RS10280 SP_RS10330 pyruvate pyruvate 1-acyl-sn-glycerol- beta-ketoacyl- hypothetical a reduced α SP_RS08255 carboxylase methionine protein RS00500 form [Fe-S] cluster biosynthesis SP_RS02255 aminomethylpyrimidine -D-muramoyl- phosphate D-xylulose dehydrogenase dehydrogenase pyruvate glycerophosphoryl HAD family 3-phosphate alpha- peptidoglycan ACP protein: di-trans,octa-cis thioredoxin γ acetate 1-acyl-sn-glycerol- glycerol-3- biotin carboxyl (R)-S-oxide kinase CpsD: RS03705 scaffold protein] chaperone]-ATP thiaminase II: L-alanyl- -D- D-alanyl-D-alanine peptidoglycan biosynthesis I isomerase: pgi 5-phosphate E1 subunit alpha: E1 subunit alpha: 1-alkyl-2- ribonuclease 3: 4-hydroxy- diester peptidyl-tRNA hydrolase: methionine acyltransferase: galactosidase: glutamyl GlcNAc saccharopine aminopeptidase reductase: SP_RS00205 -undecaprenyl a [lipoyl-carrier 3-phosphate phosphate carrier protein reductase: SP_RS01705 SP_RS03535 glutamyl-L-lysine (meso-diaminopimelate containing) SP_RS05740 SP_RS05740 acetylglycerophosphocholine SP_RS06115 tetrahydrodipicolinate phosphodiesterase: hydrolase: SP_RS08660 aminopeptidase: 1-cis-vaccenoyl-SP_RS08010 SP_RS09430 aminopeptidase: deacetylase: dehydrogenase: N: SP_RS03900 SP_RS02080 beta-ketoacyl- a [protein]- S-ribosylhomocysteine 6 F6P two reduced phosphate protein]-N -[(R pyruvate fermentation acyltransferase: esterase: SP_RS07125 acyltransferase: synthase: SP_RS05035 SP_RS00025 SP_RS05360 2-palmitoleoyl SP_RS09255 SP_RS07265 SP_RS04545 hypothetical ACP subunit: a protein-L-SP_RS03240 L-tyrosine lyase: SP_RS01655 UDP-N-acetyl- dihydrolipoyl SP_RS04930 [+ 7 isozymes] cysteine residues )-lipoyl]-L-lysine 4-amino-2-methyl-5- UDP-N- to acetate II SP_RS08010 SP_RS04175 phosphatidate protein: reductase: SP_RS02090 methionine- phosphate RS08735 α-D-glucosamine 6-phosphofructokinase: dehydrogenase: α in a protein S-ribosylhomocysteinase: pyrimidinemethanol acetylmuramoyl- a 1-alkyl-2-lyso- RNase III -D-galactose sucrose [+ 3 isozymes] RS00810 UDP-N-acetylglucosamine SP_RS04420 SP_RS05725 an mRNA fragment (2S,4S)-4- an uncharged an N-terminal L- S-trans-1- a deacetylated a (5Z)-3-oxo-SP_RS00205 a cis-delta17-3-SP_RS02080 (R)-S-oxide SP_RS11685 tripeptide-- pyruvate a [pyruvate dehydrogenase 1-palmitoyl-2- sn-glycero-3- acetate 1-cis- processing hydroxy-2,3,4,5- glycerol sn-glycerol an N-modified an (R)-2- met propenyl- Glu acetate allysine Glu ala a peptide malonyl-CoA 1-carboxyvinyltransferase: β-D-fructose 1,6- pyruvate a [pyruvate dehydrogenase E2 product mRNA amino acid tRNA a halide anion threonyl-[protein] peptidoglycan tetradec-5- hydroxyC36:1- D-alanyl-D- E2 protein] N 6 -S- acyl-carrier protein palmitoleoyl phosphocholine acyl-carrier protein vaccenoylglycerol- tetrahydrodipicolinate 3-phosphate hydroxyacid L-cysteine SP_RS09880 protein] N 6 -dihydrolipoyl-L-lysine enoyl-[acp] [acp] predicted alanine ligase: bisphosphate dehydrogenase acetyldihydrolipoyl-L-lysine phosphatidate 3-phosphate ATP-driven UDP-N-acetylglucosamine E1 subunit alpha: Zn 2+ Zn 2+ Amino Acid Biosynthesis SP_RS08250 transporter Fatty Acid and Lipid Biosynthesis 1-carboxyvinyltransferase: fructose- SP_RS05740 RS04385 adenine 2503 N-acetyl-D-glucosaminyl-N- a single- sn-glycero-3- a 2'- 4-hydroxy-2- a cytidine 1402 an N-terminal- γ-L-glutamyl-(S)- (3R,5S)-1- an L-1- of Zn2+ UDP-N-acetyl- SP_RS05345 bisphosphate acetyl-CoA H O coenzyme A [EntF L-seryl- 1-myristoylglycerol formate DNA with lesion a 3-oxooctanoyl- a cis-delta21-3- acetylmuramoyl-L-alanyl-D-glutamyl- diphosphate 2 deoxyribonucleoside nonenal-[Cys- L-cystathionine L-methionyl-L- pyrroline-3- phosphatidyl- ala nitrate RS11230 nitrate superpathway of L- α-D-muramoyl- UDP-N-acetyl-α- aldolase: pyruvate in 23S rRNA carrier protein] stranded RNA phosphoethanolamine [DNA] 3-phosphate in 16S rRNA methyl-L-cysteine CTP [acp] oxo-C40:1-[acp] phosphatidylglycerol superpathway of branched chain amino acid biosynthesis L-tryptophan biosynthesis L-alanine phosphate 6-carboxy-L-lysyl-D-alanine 5'-triphosphate Gly] conjugate ribosomal RNA alanyl-[protein] excinuclease hydroxy-5- sn-glycerol phosphatidylglycerol biotin-carboxyl carrier gondoate biosynthesis fatty acid elongation -- saturated isoleucine biosynthesis I L-alanyl-γ-D- D-glucosamine- SP_RS02975 dehydrogenase 1-acyl-sn-glycerol- hypothetical hypothetical biosynthesis II biosynthesis III acetyltransferase: acetyl-CoA 3-phosphate small subunit ABC subunit A: protein: protein: carboxylatepyrroline-5- lipid kinase: alanine predicted biosynthesis I (plastidic) protein assembly (anaerobic) fatty acid glutamyl-L-lysyl- enolpyruvate E1 subunit alpha: 23S rRNA polyribonucleotide glycerophosphoryl glutamyl anaerobic racemase: RS01635 (non-plastidic) oxaloacetate SP_RS05445 manganese- holo-ACP polymerase: cysteine acyltransferase: methyltransferase methionine SP_RS00920 SP_RS00205 SP_RS00205 carboxylate SP_RS05175 ABC a [biotin biosynthesis thr pyruvate chorismate D-alanyl-D-alanine UDP-N- SP_RS05740 (adenine(2503)-C(2) LD-carboxypeptidase: nucleotidyltransferase: diester aminopeptidase aminopeptidase: ribonucleoside- SP_RS08395 Mn 2+ Mn 2+ an acetoacetyl-[acp] aspartate cys triose- dependent inorganic synthase: SP_RS09400 desulfhydrase: SP_RS08010 4 H: SP_RS01630 aminopeptidase: excinuclease reductase: transporter DHAP DHAP carboxyl-carrier initiation I acetylenolpyruvoylglucosamine acetyl phosphate )-methyltransferase SP_RS00905 SP_RS02910 phosphodiesterase: N: SP_RS03900 1-myristoyl-2- an N - SP_RS09255 triphosphate beta-ketoacyl- beta-ketoacyl- 1-(3-sn- a malonyl-[acp] an oleoyl-[acp] acetolactate phosphate pyrophosphatase: SP_RS08400 1402 of Mn2+ glycerol-3- glycerol-3- aminotransferase: galactose-1-phosphate cysteine RlmN: SP_RS03750 SP_RS04930 [+ 8 isozymes] SP_RS07505 palmitoleoyl methylcytidine SP_RS05360 ABC subunit B: ACP ACP trans-4-hydroxy-SP_RS04615 phosphatidyl) D-ala protein]-L-lysine acetyl-CoA L-serine synthase: reductase: SP_RS06785 isomerase: SP_RS07555 reductase: predicted phosphate phosphate SP_RS07605 uridylyltransferase: desulfurase: Alcohol Degradation phosphatidate in 16S rRNA SP_RS06070 reductase: reductase: L-proline -sn-glycerol bifunctional acetyl-CoA dehydratase, SP_RS02190 SP_RS09160 SP_RS04280 UDP-N-acetyl- UDP-N- SP_RS07760 acetate kinase: N-acetyl-D-glucosaminyl-N- a holo-[EntF a nucleoside a single- 4-hydroxy-2- SP_RS00980 DNA without ABC dehydrogenase dehydrogenase aspartate D-glyceraldehyde 3',5'-ADP an N-terminal L- S-methyl- SP_RS02080 SP_RS02080 3-phosphate RS01585 glycine glycine biotin-- (11Z)-3-oxo- carboxylase iron-sulfur- α-D-muramoyl- acetylenolpyruvoylglucosamine DHAP SP_RS10330 a 2-methyladenine 2503 acetylmuramoyl-L-alanyl-D- L-seryl-carrier stranded RNA Glu lesion a (3R)-3- a cis-delta21-3- transporter (NAD(P)(+)): (NAD(P)(+)): aminotransferase: acetolactate [+ 2 isozymes] 3-phosphate glycerol and glycerophosphodiester degradation 5'-deoxyadenosine D-ala diphosphate ethanolamine sn-glycerol [DNA] nonenal-[L- gly 2-oxobutanoate cys met L-cysteine betaine betaine [acetyl-CoA- icos-11-enoyl- carboxyl dependent anthranilate L-alanyl-γ-D- reductase: SP_RS06815 in 23S rRNA met glutamyl-6-carboxy-L-lysine H + protein] alanyl-[protein] hydroxyoctanoyl- hydroxyC40:1- of glycine SP_RS10645 SP_RS10645 a 3-oxoacyl-[acp] SP_RS08935 synthase ala glyceraldehyde- Fatty Acid and phosphate 3-phosphate Cys] conjugate dCTP sn-glycerol sn-glycerol carboxylase] [acp] synthase: transferase subunit beta: glutamyl-L- ala UDP-N-acetyl- acetate [acp] [acp] betaine small subunit: anthranilate 3-phosphate Lipid Degradation arg arg 3-phosphate 3-phosphate synthetase/ SP_RS02085 beta-ketoacyl- subunit beta: asp SP_RS00540 lysyl-D-alanine α-D-muramate a glycerophosphodiester Mg 2+ RS08665 Mg 2+ SP_RS02195 phosphoribosyltransferase: dehydrogenase: glycerol RS10970 biotin operon ACP SP_RS02105 [+ 2 isozymes] Inorganic Nutrient Metabolism glycerol-3- glycerol-3- SP_RS09010 triacylglycerol UDP-N-acetyl- decaprenyl-diphospho-N- a DNA containing γ β 1-cis- 527 an N-terminal- an (L- a (9Z)-3-oxo- 2-dehydro- a (1->4)- repressor: reductase: aspartate UDP-N- Glu SP_RS10185 a tRNA precursor with a 5' [EntB aryl- -L-glutamyl-(S -D-fructofuranose a guanine an N-terminal L- sn-glycerol a cis-delta13-3- arg RS03000 arg an (11Z)-3-oxo- acetyl-CoA (2Z)-2-aminobut- (S)-2-acetolactate degradation α coenzyme A phosphocholine α 2+ 2+ ornithine ornithine phosphate phosphate SP_RS09440 kinase: acetylmuramate-- glycerophosphoryl glycerol kinase: -D-glucosamine acetylmuramoyl-pentapeptide DL-allothreonine an apurinic/ )-allyl-L-cysteine 1-phosphate CTP vaccenoylglycerol- in 16S rRNA L-methionyl-L- glutamyl-[protein] cysteinylglycine) 3-phosphate octadec-9- 3-deoxy-D- -D-glucan ATP Mg RS00915 Mg icos-11-enoyl-[acp] SP_RS02080 carboxylase 2-enoate N-(5-phosphoribosyl)-anthranilate extension and a short 3' extension carrier protein] ATP oxo-C32:1-[acp] glycogen- acyltransferase: acyltransferase: a [biotin carboxyl- SP_RS02045 ketol-acid L-asparagine undecaprenyl- L-alanine ligase: glutamate 13-DPG urea cycle diester SP_RS11165 apyrimidinic site 4'-phosphopantetheine 3-phosphate1-acyl-sn-glycerol- ribosomal RNA seryl-[protein] -S-conjugate glycerol-3- enoyl-[acp]beta-ketoacyl- hypothetical gluconate2-keto-3- hypothetical carboxyl a triglyceride thiosulfate branching an acid RS06040 an acid SP_RS04175 SP_RS04175 carrier protein]-N beta-ketoacyl- reductoisomerase: biosynthesis II diphospho-N- SP_RS07490 racemase: phosphodiesterase: hypothetical protein: undecaprenyldiphospho- 3-phosphate small subunit phosphate ACP protein: deoxygluconate adenylate a 1-acyl-sn a 1-acyl-sn β-ketoacyl- protein: transferase L-aspartyl- N-(5'-phosphoribosyl) tributyrin disproportionation glutamyl fructose- phosphorylcholine glutamyl enzyme: Mg 2+ RS09045 Mg 2+ 6 -biotinyl-L-lysine ACP reductase: acetylmuramoyl- SP_RS09330 phosphoglycerate SP_RS04930 SP_RS11110 muramoylpentapeptide beta-N- holo-ACP acyltransferase: methyltransferase methionine acyltransferase: reductase: SP_RS00205 cyclase: -glycerol 3- -glycerol 3- ACP synthase: SP_RS00205 4-phosphate SP_RS02200 anthranilate isomerase: esterase: arg IV (rhodanese) serine aminopeptidase: bisphosphate transferase LicD: aminopeptidase: aminopeptidase kinase: SP_RS05550 2+ 2+ subunit alpha: γ synthase: phosphopantetheine 7 G: SP_RS06300 Cu RS11390 Cu SP_RS02080 (2R)-2,3- SP_RS09000 asp L-alanyl- -D- UDP-N-acetyl- kinase: SP_RS02455 acetylglucosaminyltransferase: protein component: 1,2-dicis- SP_RS08010 an N - aminopeptidase: 1-[18- SP_RS04175 SP_RS02080 beta-ketoacyl- SP_RS01545 a (1,6)-α-D- SP_RS05425 phosphate phosphate SP_RS02085 a (3R)-3- SP_RS02110 SP_RS03015 thiosulfate hydroxymethyltransferase: glyA SP_RS08400 III: SP_RS06270 adenylyltransferase: SP_RS09255 aldolase: SP_RS06240 SP_RS09255 N: SP_RS03900 hypothetical a 2,3,4-saturated aspartate- 2-iminobutanoate dihydroxy-3- asparagine glutamyl-L- α-D-muramoyl- D-glt SP_RS03375 SP_RS10325 vaccenoyl- methylguanine 527 SP_RS05360 Co 2+ RS07050 Co 2+ 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- hydroxyacyl-[acyl- malonyl-CoA 1-(o-carboxyphenylamino)-1'- a 1,2-diglyceride ammonium sn-glycerol 3-phosphate SP_RS02975 [+ 2 isozymes] hydroxyoleyl]- hypothetical ACP KDGP glucosyl-(1,4) cyclic-AMP protein: fatty acyl-[acp] semialdehyde methylbutanoate synthetase A: lysyl- D-alanine L-alanine 3-phospho-D-glycerate SP_RS09895 phosphatidate in 16S rRNA α predicted 3-phosphate 3-phosphate a [biotin carboxyl- 3-hydroxyacyl-carrier protein] deoxyribulose 5'-phosphate undecaprenyldiphospho- argininosuccinate 2-lyso- protein: reductase: - -glucan SP_RS00205 dehydrogenase: 2,3-dihydroxy- SP_RS09905 muramoylpentapeptide beta-N- carbamoyl rhodanese: decaprenyl-pyrophosphoryl- a holo-[EntB aryl- a 3'-terminal a 5'-phospho- phosphatidate SP_RS00205 SP_RS02080 ABC acyltransferase: acyltransferase: carrier-protein [acp] malonyl CoA- indole-3-glycerol- phosphoglycerate glycerol-3-phosphate UDP 3',5'-ADP S-allyl-L-cysteine Glu an N-terminal a protein Glu an L-cysteine- a (3R,9Z)-3- a cis-delta13-3- 2+ 2+ Na + Na + asn UDP-N- lyase: SP_RS00320 acetaldehyde gly a tRNA precursor with gly Co RS03520 Co 6 acyl carrier SP_RS05030 isovalerate acetylglucosaminyltransferase: phosphate SP_RS03065 (N-acetylglucosamine)-N- a tRNA fragment carrier protein] unsaturated sugar [DNA] 3'-dephospho- DHAP D-glyceraldehyde met transporter SP_RS08010 SP_RS08010 dimer]-N - a (3R,11Z)-3-hydroxy- dehydratase: phosphate synthase: acetylmuramoyl- mutase: dehydrogenase: a short 3' extension CDP-choline L-seryl-[protein] S-conjugate hydroxy-octadec- hydroxyC32:1- of Na+ a 1,2-diacyl- a 1,2-diacyl- biotinyl-L-lysine SP_RS02085 protein L-aspartate- dehydratase: ditrans,octacis-SP_RS03375 SP_RS08170 synthase acetylmuramyl-(pentapeptide) CoA icos-11-enoyl-[acp] 2-oxobutanoate SP_RS09005 L-alanine--D- phosphate SP_RS11160 9-enoyl-[acp] [acp] glycerol RS11155 glycerol sn-glycerol sn-glycerol acetyl-CoA transacylase: semialdehyde SP_RS10850 undecaprenyldiphospho- a 2-acylglycerol L-arginino- large subunit: Co 2+ RS02395 Co 2+ (3R,11Z)-3- (1S,2R)-1-C-(indol-3- glutamate ligase: L-ornithine thiocyanate sulfite acquisition 3-phosphate 3-phosphate carboxylase SP_RS02075 acetolactate 3-methyl-2- N-acetyl-(N- 2-phospho-D-glycerate succinate SP_RS04365 DHAP hydroxy-icos- homoserine yl)glycerol 3-phosphate SP_RS03370 10 a 2,3,4-saturated N-acetyl-β- DNA combined with a (9Z)-3- phosphatidate phosphatidate an N - an insertion sequence + a negatively a [protein]- carboxyl dehydrogenase: synthase: oxobutanoate acetylglucosaminyl) [+ 2 isozymes] a phosphate an L-methionyl- hydrogen cyanide a sulfurated coenzyme A an acyl- a glycogen phosphate L-selenocystathionine 1-palmitoylglycerol NADP FMNH tributyrin a cis-delta19-3- a DNA segment methylglyoxal RS00065 cytidylyltransferase: cytidylyltransferase: 11-enoyl-[acp] L-glutamate γ enolase: Met formyltetrahydrofolate 1,2-diacyl-sn- neuraminate exogenous DNA to form propanoyl-CoA element IS30 2 a protein supercoiled DNA oxohexadec- L-histidine a cation RS09215 a cation transferase acetyl-CoA 2,3,4-saturated- a malonyl-[acp] SP_RS06665 SP_RS02190 tryptophan synthase muramoyl-L-alanyl- -D- UDP-N-acetyl- carbamoyl monoester [initiator tRNA ] [sulfur carrier] carrier protein CTP 3-phosphate oxo-C38:1-[acp] SP_RS01285 SP_RS01285 dehydratase: a trans-2- 2-isopropylmalate biosynthesis III meso- SP_RS05590 acid glycerol 3-phosphate a recombinational Hollidayjunction junction 1-acyl-sn-glycerol- transposase: DNA 9-enoyl-[acp]hypothetical hypothetical recombinase glyoxalase: histidine subunit beta: carboxylase a 2,3,4-saturated fatty-acid-[acp] acetolactate branched chain subunit alpha: glutamyl-L-lysyl-D-alanine α-D-muramoyl-L- phosphate SP_RS02095 enoyl-[acyl- 3-oxoacyl-ACP synthase: diaminopimelate a 1-monoglyceride ornithine phosphatase: maltodextrin resolvase RuvX: 3-phosphate SP_RS07315 topoisomerase protein: protein: RarA: SP_RS07600 kinase: a CDP- a CDP- SP_RS02105 biotin fatty acyl-[acp] reductase: L-homoserine synthase amino acid SP_RS08990 alanyl-D-glutamate argininosuccinate N-acetylneuraminate cystathionine flavin tributyrin a cation RS07655 a cation carrier protein] synthase III: SP_RS06170 2-oxoglutarate phosphoenolpyruvate carbamoyltransferase: SP_RS09640 methionyl-tRNA rhodanese: holo-ACP phosphatidate phosphorylase: SP_RS00945 phosphate acyltransferase: [+ 30 isozymes] IV subunit B: SP_RS00205 SP_RS00205 SP_RS08885 glyoxalase: SP_RS11430 diacylglycerol diacylglycerol acetyl-CoA carboxylase a (2E,11Z)-icosa- SP_RS02080 small subunit: aminotransferase: tryptophan synthase: lyase: SP_RS06525 beta-lyase: reductase: esterase: endopeptidase: SP_RS02060 glutamate SP_RS10960 phosphate formyltransferase: SP_RS03065 synthase: cytidylyltransferase: SP_RS10735 acyltransferase: SP_RS08010 an insertion SP_RS04180 a DNA segment SP_RS00385 a [protein]- RS06350 CDP-diacylglycerol-- CDP-diacylglycerol-- carboxylase subunit: 2,11-dienoyl-[acp] homoserine SP_RS02195 SP_RS04195 synthase subunit UDP-N- pyruvate SP_RS00575 N-acetylneuraminate Holliday junction SP_RS03305 1-palmitoyl-2- SP_RS02775 SP_RS03015 SP_RS08130 beta-ketoacyl- beta-ketoacyl- dehydrogenase: ditrans,octacis- L-citrulline SP_RS08585 SP_RS08400 SP_RS01285 SP_RS00225 sequence IS30 with [+ 2 isozymes] in reverse (R)-lactate N-phospho- a cation RS08005 a cation glycerol-3-phosphate 3- glycerol-3-phosphate 3- carboxyl SP_RS02100 (2E,11Z)-icosa- kinase: (S)-2-aceto-2- (2S)-2- beta: SP_RS08995 acetylmuramoylalanyl- kinase: lyase: SP_RS08280 resolvase RecU: cis-vaccenoyl ACP ACP 2,3,4-saturated an acetoacetyl-[acp] isopropylmalate SP_RS06400 undecaprenyldiphospho- α-D- phosphatidate integrated transposon a relaxed DNA reductase: reductase: orientation L-histidine phosphatidyltransferase: phosphatidyltransferase: transferase 2,11-dienoyl- SP_RS06660 hydroxybutanoate D-glutamate--2, 6- SP_RS04425 glycerol α resolution of recombinationalSP_RS01805 val indole ser Glu N-acetyl-(N- D-ala thiocyanate an unsulfurated an -limit dextrin seleno-L- + SP_RS11345 SP_RS11345 subunit alpha: [acp] reductase: fatty acyl- O-phospho- (2S)-2- diaminopimelate an N-formyl- 3',5'-ADP acyl-carrier protein a CDP-2,3,4-saturated- glucopyranose N-acetyl-β-D- junction formation propanoyl pyruvate FMN NADPH H butanoate 1,2-dibutyrin a (3R,9Z)-3-SP_RS02080 a cis-delta19-3-SP_RS02080 Peptide RS01180 Peptide ketol-acid acetylglucosaminyl) pyruvate a tetrahydrofolate [sulfur carrier] homocysteine a peptide a peptide RS02370 1-(3-sn- 1-(3-sn- SP_RS02110 SP_RS02070 acyl-ACP [acp]:NAD+ L-homoserine isopropylmalate ligase: SP_RS07550 L-methionyl- diacylglycerol 1-phosphate mannosamine pyruvate of two intact strands phosphate hydroxyhexadec- hydroxyC38:1- reductoisomerase: muramoyl-L-alanyl- D-alanine- met phosphatidyl) phosphatidyl) a [carboxyl-carrier : hydro-lyase (2- [initiator tRNA ] 9-enoyl-[acp] [acp] threonine SP_RS02200 tryptophan γ-D-isoglutaminyl- -D-alanine Fermentation -sn-glycerol -sn-glycerol protein dimer]-N 6 a gondoyl-[acp] pathway SP_RS01555 isopropylmaleate- synthase subunit UDP-N-acetyl- Peptide GlnQ Peptide synthase: (R)-2,3-dihydroxy- L-lysyl-D-alanine α ligase A: 3-phosphate 3-phosphate -carboxybiotinyl- an acyl-[acyl- forming): beta: SP_RS08995 -D-muramoyl- SP_RS10445 3-methylpentanoate SP_RS08255 an apo-[LYS2 L- a linear malto- 2605 a (7Z)-3- UDP-N-acetyl- D-ribulose γ pyruvate 7,8- a [lipoyl-carrier 1-palmitoylglycerol + sn-glycerol uridine RS06820 L-lysine carrier protein] SP_RS06150 L-glutamate L-alanyl- -D- acetoacetyl-CoA acetyl-CoA H O coenzyme A ethylnitronate coenzyme A maltopentaose (R)-lipoate O-ureido-L- an acyl phosphate NAD FMNH α-D-glucosamine Peptide RS03455 Peptide acyl-ACP 2,3-dihydroxy-3- superpathway fermentation to dihydromonapterin 2 2-aminoadipyl- oligosaccharide VibB protein]-L-lysine asp 2 asp in 23S rRNA oxohexacos- thr 5-phosphate cys biosynthesis II glutamyl-meso-2,6- D-alanyl-D-alanine 3-phosphate 3-phosphate thioesterase: thr methylvalerate 2-isopropylmaleate of L-threonine (R)-acetoin II Polymeric Compound Degradation carrier-protein] homoserine 1-acyl-sn-glycerol- glycerol-3- ribosomal 7-enoyl-[acp]hypothetical ribulose- an L-1- an L-1- trp ditrans,octacis- diaminopimelate aspartate L-serine toxin PezT: cysteine SP_RS06900 hydro-lyase: biosynthesis maltodextrin maltodextrin 3-phosphate acylphosphatase: phosphate large subunit protein: phosphate 3- phosphatidyl- phosphatidyl- 2-oxoglutarate undecaprenyldiphospho- pyruvate bifunctional dihydroneopterin hydroxymethylglutaryl- 2-nitropropane lipoate--protein flavin aminotransferase: dehydratase, SP_RS05200 desulfhydrase: a fatty acid L-serine SP_RS10850 (2R,3S)-3- chitin degradation II (Vibrio) chondroitin sulfate degradation I (bacterial) holo-ACP phosphorylase: holo-ACP phosphorylase: argininosuccinate acyltransferase: SP_RS09925 acyltransferase: pseudouridine SP_RS00205 epimerase: sn-glycerol sn-glycerol oxaloacetate glutamate N-acetyl-(N- UDP-N- acetolactate hyaluronan degradation aldolase/2-amino-4-hydroxy-6- CoA synthase: dioxygenase: ligase A: reductase: SP_RS07605 iron-sulfur- UDP-N-acetyl-α- SP_RS07505 RS07690 dehydratase, isopropylmalate synthase: synthase: synthase: SP_RS08010 α ωSP_RS04175 synthase B: SP_RS09965 Peptide RS03365 Peptide (S)-3-methyl-2- aspartate dehydrogenase: acetylglucosaminyl) acetylmuramoyl- synthase: hydroxymethyldihydropteridine SP_RS08545 SP_RS02070 SP_RS10735 SP_RS10735 SP_RS05720 1-palmitoyl- SP_RS02775 1-C16:0- , - aspartate beta-ketoacyl- dependent D-xylulose iron-sulfur- hydro-lyase (2- SP_RS08400 SP_RS08400 SP_RS00575 a carboxylate SP_RS09295 D-glucosamine pyruvate γ chitin 2-myristoyl dicarboxyl-2- 2605 oxopentanoate aminotransferase: SP_RS06400 muramoyl-L-alanyl- -D- tripeptide-- SP_RS02190 chondroitin sulfate A hyaluronan diphosphokinase: SP_RS01435 aminotransferase: a pseudouridine ACP subunit beta: 3'-phosphate 5-phosphate dependent isopropylmaleate- β D-alanyl-D- α-D- a linear malto- α-D- phosphatidate lysophosphatidate reductase: branched chain SP_RS07605 Glu isoglutaminyl-N-( -D- acetolactate a holo-[LYS2 L- [unspecified maltotetraose a [lipoyl-carrier SP_RS08935 in 23S rRNA SP_RS00540 subunit beta: forming): L-proline chondroitin a holo-[VibB aryl- + Secondary Metabolite Biosynthesis amino acid aspartate asparatyl)-L-lysyl-D-alanine alanine ligase: synthase hyaluronate HMG-CoA 3',5'-ADP 2-aminoadipyl- acetaldehyde nitrite degradation glucopyranose oligosaccharide 3',5'-ADP glucopyranose protein]-N 6 -[(R FMN NADH H oxaloacetate a (3R,7Z)-3-SP_RS02080 [+ 2 isozymes] Peptide RS04510 Peptide RS00585 SP_RS00540 SP_RS06150 biosynthesis I sulfate A 6-(hydroxymethyl) glycolaldehyde carrier protein] canavaninosuccinate aminotransferase: aminotransferase: SP_RS08250 small subunit: lyase: carrier-protein] products] 1-phosphate 1-phosphate )-lipoyl]-L-lysine hydroxyhexacos- 2-oxobutanoate [+ 2 isozymes] (2R,3S)-3- endolyase: -7,8-dihydropterin autoinducer AI-2 biosynthesis I SP_RS04195 SP_RS08935 SP_RS02195 a chitodextrin SP_RS01530 7-enoyl-[acp] myo-inositol (2Z)-2-aminobut- isopropylmalate UDP-N-acetyl- SP_RS01530 Glu (S)-2-acetolactate chondroitin sulfate C 3-(4-deoxy- biosynthesis 2-enoate 3-isopropylmalate asp L-alanine ditrans,octacis- α-D-muramoyl- 4-deoxy-β-D-gluc-4- β-D-gluc-4- ile glutamate biosynthesis II N-acetyl-β-D-glucosamine- a long-linear a (1->4)- a 1-acyl-sn predicted RS05350 dehydrogenase: undecaprenyldiphospho- L-alanyl-γ-D- alpha- enuronosyl-(1,3)-N-acetyl- enuronosyl) a nascent peptidoglycan with (L- D-glyceraldehyde D-sedoheptulose RNase R degradation an (R)-2- 1-palmitoylglycerol 1-oleyl-2-lyso- sn-glycerol a double- D-ribose 5- α Amine and Polyamine Biosynthesis SAM D-glucopyranose aspartate 5-kinase: chondroitin γ maltohexaose α a tripeptide α spermidine L-cysteate formate (R)-mevalonate -amylose ABC SP_RS06130 N-acetyl-(N- glutamyl-meso-2,6- di-trans,octa-cis acetolactate D-galactosamine 4-sulfate -N-acetyl-D- alanyl- -D-glutamyl-meso-2,6- 3-phosphate 7-phosphate 1,6-anhydro-N- substrate RNA halocarboxylate -D-glucan -D-glucan 3-phosphate phosphatidate -glycerol 3- 3-phosphate UTP helix DNA phosphate Peptide Peptide 6-phosphate kinase: γ SP_RS04605 pyruvate sulfate B β DNA helicase glycogen- transporter -L-glutamyl acetylglucosaminyl) diaminopimeloyl- -undecaprenyl decarboxylase: a chitodextrin glucosamine diaminopimeloyl-D-alanine) tetrapeptide acetyl- -D-muramate 1-acyl-sn-glycerol- spermidine aspartate 1-acyl-sn-glycerol- phosphate1-acyl-sn-glycerol- glycerol-3- mevalonate ribose-5- spermidine biosynthesis III (2S)-2-isopropyl- SP_RS02045 5-phosphate alanine endolyase: aminotransferase: 3-phosphate RecG: phosphate branching of a peptide 2-iminobutanoate muramoyl-L-alanyl- D-alanyl-D-alanine phosphate SP_RS06825 maltodextrin maltodextrin maltodextrin 3-phosphate acetyltransferase: 3-phosphate phosphate kinase: putrescine biosynthesis II 3-oxosuccinate aminotransferase: γ SP_RS01530 transketolase: ribonuclease R: HAD family peptidase T: SP_RS07605 acyltransferase: anaerobic SP_RS08390 isomerase: enzyme: Peptide RS08155 Peptide RS11730 SAH L-aspartyl- gamma- -D-isoglutaminyl- unsaturated beta-N- phosphorylase: phosphorylase: phosphorylase: acyltransferase: SP_RS05060 acyltransferase: acyltransferase: SP_RS01870 Ins(3)P SP_RS10035 β 4-deoxy-β-D-gluc-4- 4-deoxy-β-D-gluc-4- LD-carboxypeptidase: SP_RS07965 SP_RS04835 hydrolase: SP_RS05000 SP_RS08010 ribonucleoside- [+ 2 isozymes] SP_RS04050 SP_RS05550 glutamyl- N-( -D-asparaginyl) (R)-acetoin chondroitin acetylhexosaminidase: SP_RS10735 SP_RS10735 SP_RS10735 1-palmitoyl-2-SP_RS08010 N 1 - aspartate SP_RS08010 SP_RS04175 an unwound (R)-mevalonate arg SAM 4-phosphate enuronosyl-(1,3)-N-acetyl- enuronosyl-(1,3)-N- SP_RS00905 [+ 2 isozymes] SP_RS08660 dioleoyl a 1-acyl-2- 1-oleyl-2-lyso- triphosphate D-ribulose arg 5'-methylthioadenosine/ phosphate ala -L-lysyl-D-alanine disaccharide SP_RS00325 palmitoleoyl acetylspermidine aminotransferase: double- 5-phosphate amylopectin inositol -D-galactosamine 6-sulfate acetyl-D-galactosamine phosphatidate palmitoyl-sn phosphatidate reductase: 5-phosphate Peptide RS05285 Peptide S-adenosylhomocysteine 4-methyl-2- aspartate- reductase: beta-N- α α α SP_RS08935 arginine arginine decarboxylase, monophosphatase: undecaprenyldiphospho- hydrolase: -D- -D- a long-linear a (1->4)- -D- phosphatidate -glycerol 3- SP_RS00980 stranded DNA nucleosidase: SP_RS04915 2-oxobutanoate oxopentanoate semialdehyde SP_RS04610 acetylhexosaminidase: a nascent peptidoglycan with D-ribose 5- D-xylulose a diribonucleotide a nucleoside 5'- an (S)-2- maltopentaose α a proteinogenic a dipeptide α RS09765 decarboxylase, biosynthetic: SP_RS06875 N-acetylmuramoyl-L- unsaturated unsaturated SP_RS01565 1,6-anhydro-N- a halide anion glucopyranose glucopyranose -D-glucan -D-glucan glucopyranose 3-sulfopyruvate phosphate L-asparagine dehydrogenase: γ SP_RS00325 (L-alanyl-γ-D-glutamyl-meso- D-ala phosphate 5-phosphate GlcNAc monophosphate hydroxycarboxylate amino acid Peptide RS06085 Peptide biosynthetic: SP_RS04525 S-ribosyl-L-homocysteine branched chain L-glutamate-5- a peptidoglycan alanyl- -D-glutamyl-meso N,N'- N,N',N''- chondroitin chondroitin acetyl-β-muramate 1-phosphate 1-phosphate 1-phosphate agmatine myo-inositol acetolactate biosynthesis III SP_RS05030 4-deoxy-L- N-acetyl-D- 2,6-diaminopimelate) tripeptide dUTP SP_RS04525 dAdoMet amino acid semialdehyde dimer -2,6-diaminopimeloyl- diacetylchitobiose triacetylchitotriose disaccharide disaccharide synthase: (tRNA-dependent) threo-hex-4- glucosamine S-ribosylhomocysteine aminotransferase: L-aspartate- (tetrapeptide) D-alanyl-D-alanine beta-N- hydrolase: hydrolase: Peptide RS04745 Peptide agmatine deiminase: SP_RS02190 semialdehyde undecaprenyldiphospho- enopyranuronate RS03570 agmatine lyase: SP_RS01655 asp SP_RS04195 acetylhexosaminidase: SP_RS01565 SP_RS01565 UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N-acetylmuramoyl-L- a long-linear a ring-opened 7- an (S)-2- a plant soluble a dietary all- a 1-alkyl-sn a [lipoyl-carrier an oxidized a (1->4)- SP_RS04555 acetolactate muramoylpentapeptide beta-N- α-D-glucopyranose + maltotetraose β-D-galactose a D-hexose SP_RS00325 alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine α-D-glucan H hydrogencarbonate heteroglycan RX glutathione spermidine -glycerol 3- Ins(1)P protein]-N 6 -[(R) wound RNA DHAP nitroaromatic α-D-glucan S-ribosylhomocysteinase: synthase aspartyl- homoserine methylguanine in DNA halocarboxylate trans-retinyl ester L-homoserine Asn leu acetylglucosaminyltransferase: galactose glycogen- predicted polyamine N-carbamoylputrescine SP_RS11685 tRNA dehydrogenase: (S)-1-pyrroline- a peptidoglycan N-acetyl-D- 4-deoxy-L-threo-hex- spermidine phosphate1-acyl-sn-glycerol- -dihydrolipoyl]- RNA helicase: glycerol-3- compound small subunit: SP_RS03375 undecaprenyldiphospho- homoserine O- inositol NAD(P)H mutarotase: glucokinase: branching ABC aminopropyltransferase: synthetase: SP_RS06665 5-carboxylate tetramer with L,D glucosamine 4-enopyranuronate 4-alpha- maltodextrin maltodextrin acetyltransferase: 3-phosphate L-lysine SP_RS07285 phosphate Peptide Peptide AI-2 SP_RS02195 lipid II (meso muramoylpentapeptide beta-N- formamidopyrimidine- carbonate HAD family glutathione S- tributyrin succinyltransferase: monophosphatase: dihydrolipoyl nitroreductase: SP_RS00365 SP_RS03280 enzyme: transporter RS03360 SP_RS04540 N-carbamoylputrescine SP_RS07595 pyrroline-5- cross-links (L- glucanotransferase: phosphorylase: phosphorylase: SP_RS05060 acyltransferase: RNA helicase: dehydrogenase (S)-2-aceto-2- an L-aspartyl- L-homoserine diaminopimelate acetylglucosaminyltransferase: DNA glycosylase: dehydratase: hydrolase: transferase: esterase: SP_RS07770 SP_RS06875 dehydrogenase: SP_RS03050 [+ 2 isozymes] SP_RS05550 of a peptide amidase: SP_RS04560 Asn L-cysteine 8 SP_RS07500 (NAD(P)(+)): hydroxybutanoate [tRNA ] carboxylate lys-D-Asn-L-Lys) containing) SP_RS03375 SP_RS10740 SP_RS04810 SP_RS00160 SP_RS08660 SP_RS10735 SP_RS07645 SP_RS10735 SP_RS03015 N - a 2-acyl-1-alkyl-SP_RS08010 SP_RS05725 a reduced D-hexose 6- 1 O-succinyl-L- myo-inositol a [lipoyl-carrier α Peptide RS02225 Peptide S-methyl-5'- N -(3-aminopropyl) reductase: biosynthesis I acetylspermidine sn-glycerol an unwound RNA SP_RS10645 nitroaromatic -D-galactose phosphate starch putrescine ketol-acid glutamyl-tRNA(Gln) homoserine homoserine protein]-N 6 -[(R sn-glycerol thioadenosine agmatine SP_RS04615 α-D- a plant soluble α-D- 3-phosphate compound (2R,4S)-2-methyl-2,4- reductoisomerase: amidotransferase kinase: ditrans,octacis-undecaprenyldiphospho-N- UDP a short glucan a short glucan 2,6-diamino-4- an apurinic site an (S)-2- a glutathione- maltotriose )-lipoyl]-L-lysine 3-phosphate RS02285 ser CO H O a halide anion glucopyranose heteroglycan HX glucopyranose all-trans-retinol a fatty acid SP_RS02200 subunit A: gatA SP_RS06660 a peptidoglycan acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L- hydroxy-5-(N-methyl) within DNA 2 2 hydroxycarboxylate S-conjugate dihydroxydihydrofuran-3-one pro serine O- Nucleoside and Nucleotide Degradation 1-phosphate 1-phosphate RS10775 (R)-2,3-dihydroxy- an L-asparaginyl- O-phospho- with (L-alanyl- alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine formamidopyrimidine acetyltransferase: γ-D-glutamyl-L- 3-methylpentanoate [tRNA Asn ] L-homoserine spermidine SP_RS02915 superpathway of pyrimidine lysyl-D-alanyl- superpathway of purine deoxyribonucleosides degradation 2,3-dihydroxy-3- peptidyl-tRNA threonine O-acetyl-L-serine deoxyribonucleosides degradation a single D-xylulose D-erythrose adenine 1518 / an (R)-2- 1-myristoylglycerol 3-[(7'-methylthio) a uracil 1498 a double a [protein] a supercoiled a (1->4)- a (1->4)- RS04015 (2R,4S)-2-methyl-2,3,3,4- D-alanine) D-glucopyranose maltohexaose core 1 nicotinate PRPP a maltodextrin a cytosine in DNA Ins(2)P meso- α propionamide α methylvalerate hydrolase: synthase: stranded DNA 5-phosphate 4-phosphate adenine 1519 in 16S rRNA halocarboxylate heptyl]malate in 16S rRNA stranded DNA (L-serine/L- duplex DNA -D-glucan -D-glucan tetrahydroxytetrahydrofuran pentapeptide 3-phosphate diaminopimelate glycogen- glycogen- RS10790 hydro-lyase: SP_RS00025 SP_RS10445 cysteine synthase 2'-deoxycytidine ribosomal RNA DNA cytosine 1-acyl-sn-glycerol- 3-isopropylmalate 16S rRNA DNA gyrase threonine) replicative inosine 5'- inositol diaminopimelate branching amidase: branching SP_RS10850 A: SP_RS11285 2'-deoxyguanosine 4-alpha- endo-alpha-N- maltodextrin small subunit methyltransferase: 3-phosphate dehydrogenase: (uracil(1498)-N(3))- subunit B: phosphateprotein DNA helicase: phosphate nicotinate transketolase: HAD family monophosphatase: decarboxylase: enzyme: SP_RS11315 enzyme: (S)-3-methyl-2- asn thr cytidine glucanotransferase: acetylgalactosaminidase: phosphorylase: methyltransferase SP_RS02795 acyltransferase: SP_RS06130 methyltransferase: SP_RS03945 phosphatase SP_RS11250 RS03575 deaminase: 2'-deoxyadenosine degradation VII large subunit: phosphoribosyltransferase: SP_RS07965 hydrolase: SP_RS06875 SP_RS09940 SP_RS05550 SP_RS05550 oxopentanoate glycine biosynthesis I a peptidoglycan SP_RS10740 SP_RS01795 SP_RS10735 6 A: SP_RS099751518 DNA (cytosine-5-)- SP_RS08010 10-(methylthio)- 3 SP_RS08840 [+ 2 isozymes] PhpP: [+ 3 isozymes] Aromatic Compound Biosynthesis cys SP_RS05930 SP_RS06970 [+ 2 isozymes] N -dimethyladenine SP_RS08660 an N - a negatively a single propanoate with (L-alanyl- SP_RS10535 thymidine 6 1519 methyltransferase: dimyristoyl 1498 myo-inositol a GlgE-glycogen a glycogen branched chain purine-nucleoside /N -dimethyladenine 2-oxodecanoate methyluracil lys SP_RS08575 RS08015 γ-D-glutamyl-L- cytidine IMP SP_RS06560 phosphatidate supercoiled DNA a [protein] Ser/Thr stranded DNA amino acid pyrimidine- deoxyadenosine phosphorylase: IMP β-D-galactosyl- a [glycoprotein]- α-D- in 16S rRNA in 16S rRNA chorismate biosynthesis I ser lysyl-D-alanyl- deaminase: a ribonucleoside a single-stranded maltopentaose maltose D-glyceraldehyde a maltodextrin an (R)-2- a 5-methylcytosine Carbohydrate Biosynthesis 2,3-dihydroxybenzoate aminotransferase: nucleoside deaminase: SP_RS04085 dehydrogenase: (1->3)-N-acetyl- (L-serine/L- NaMN F6P glucopyranose a halide anion RS04910 serine D-alanine) SP_RS04130 5'-monophosphate oligodeoxyribonucleotide 3-phosphate hydroxyacid in DNA biosynthesis SP_RS04195 phosphorylase: SP_RS06635 SP_RS11375 D-galactosamine threonine) 1-phosphate D-erythrose hydroxymethyltransferase: glyA pentapeptide purine-nucleoside 4-phosphate deoA phosphorylase: XMP RS07920 UDP-N-acetyl-D- UDP-α-D-glucose chorismate ile gly 2'-deoxyuridine purine-nucleoside ω α glucosamine biosynthesis I 3-deoxy-7- phosphorylase: SP_RS04065 an oxidized a [dinitrogen reductase]-N - p-nitrophenyl- -D- a [2-oxoglutarate 1-chloro-2,4- 745 a 3,5,7,9,11,13,15- 746 a glucosylated biosynthesis I thymine 5 D-glucopyranose a maltodextrin an α-D-mannoside maltoheptaose chitin a guanine 3-[(5'-methylthio) an aliphatic sn-glycerol uridine phosphoenol a dextran 2'-deoxyinosine N -methyltetrahydromethanopterin α galactopyranoside dehydrogenase E2 protein] glutathione L-homoserine reduced riboflavin glycogenin RS01265 D-glucopyranose phosphoheptulonate SP_RS04085 factor 420 -( ADP-D-ribosyl)-L-arginine dinitrobenzene in 23S rRNA pentyl]malate hepta-oxo- α,ω-diamine 3-phosphate in 23S rRNA pyruvate 6 glycogen- glucan D-glucopyranose synthase: SP_RS08405 purine-nucleoside N -dihydrolipoyl-L-lysine rRNA (guanine-N1) 3-isopropylmalate hexadecanoyl-[PKS-acp] spermidine 23S rRNA flavin pyruvate 6-phosphate isochorismate dihydrolipoyl aldo/keto alpha- cysteine branching 1,6-alpha- glucose-6- 6-phosphate pyrimidine- purine-nucleoside phosphorylase: N5,N10-methylene 4-alpha- alpha- alpha- maltodextrin beta-N- -methyltransferase: dehydrogenase: acetyltransferase: pseudouridine reductase: kinase: phosphoglucomutase: phospho-2- Nucleoside and Nucleotide Biosynthesis ADP- dehydrogenase: glutathione S- reductase: glycerophosphate desulfhydrase: enzyme: glucosidase: RS03230 phosphate dehydro-3- nucleoside phosphorylase: SP_RS04065 tetrahydromethanopterin glucanotransferase: mannosidase: galactosidase: phosphorylase: acetylhexosaminidase: SP_RS10710 SP_RS06130 SP_RS05060 oxidase: synthase: SP_RS02775 SP_RS04425 SP_RS07375 isochorismatase: xanthosine ribosylglycohydrolase: SP_RS05725 transferase: 1 SP_RS03870 SP_RS07505 SP_RS05550 SP_RS01665 isomerase: pgi α-D-glucopyranose phosphorylase: SP_RS04085 reductase: SP_RS01310 SP_RS10740 SP_RS10935 SP_RS09430 SP_RS10735 a [2-oxoglutarate SP_RS00325 an N - SP_RS05440 RS11340 deoxyheptonate SP_RS07805 SP_RS05170 SP_RS07645 8-(methylthio)- 9-hydroxy-3,5,7,11,13,15- an aliphatic N- SP_RS11160 746 F6P 1-phosphate superpathway of guanosine methylguanine 745 a pseudouridine 2-oxobutanoate riboflavin a glycogen pyruvate glucose aldolase: (2S,3S)-2,3- superpathway of adenosine UMP biosynthesis III pyrimidine deoxyribonucleotides superpathway of pyrimidine deoxyribonucleoside salvage pyrimidine deoxyribonucleotides de novo biosynthesis I superpathway of pyrimidine xanthine and deoA purine-nucleoside dehydrogenase E2 2-oxooctanoate hexaoxohexadecanoyl- acetyl-diamine DHAP nucleotides de novo biosynthesis I 6 in 23S rRNA in 23S rRNA L-glutamine--D- UTP--glucose- SP_RS08410 dihydroxy-2,3- nucleotides de novo biosynthesis I biosynthesis from CTP nucleobases salvage xanthosine salvage phosphorylase: purine-nucleoside α-D- α-D- protein] N -lipoyl-L-lysine N-acetyl-D- [PKS-acp] phosphorylase: 5,10-methylene- a reduced a maltodextrin maltose a [dinitrogen a non glycosylated D-galactopyranose 4-nitrophenol maltohexaose 2,4-dinitrophenyl- chitin RS09125 fructose-6- 1-phosphate 3-deoxy- dihydrobenzoate 2'-deoxycytidine UDP CTP uracil SP_RS04065 ADP-D-ribose mannopyranose glucopyranose glucosamine gln CTP SP_RS04065 tetrahydromethanopterin factor 420 reductase]-L-arginine sugar acceptor S-glutathione RS07520 phosphate uridylyltransferase: D-arabino- IMP hydrogencarbonate ribonucleoside-diphosphate uracil 1-phosphate asp IMP xanthosine uracil 2-deoxy-α-D- 2-deoxy-α-D-ribose 1-phosphate aminotransferase: SP_RS10650 heptulosonate cytidine reductase: SP_RS05815 phosphoribosyltransferase: purine-nucleoside CDP ribose 1-phosphate SP_RS01305 7-phosphate IMP deaminase: ribonucleoside- purine-nucleoside phosphorylase: β UDP-α-D-glucose carbamoyl SP_RS03560 phosphopentomutase: 5-amino-4- a plant soluble a -D- 1-[18-hydroxyoleyl]- 3-[(3'-methylthio) D-glucopyranose D-ribulose (indol-3-yl) (R)-propane- 3-dehydroquinate 2,3- dehydrogenase: SP_RS10535 diphosphate reductase ribonucleoside-diphosphate phosphorylase: phosphopentomutase: SP_RS04085 PRPP D-glucopyranose a peptidoglycan an α-D-galactoside a glycogen (R)-mevalonate melibionate 2-phosphoglycolate a folate pyrazinamide chorismate RS10250 D-glucosamine adenylosuccinate phosphate CDP dCMP [+ 2 isozymes] SP_RS04055 imidazolecarboxyamide heteroglycan fructofuranoside 2-lyso-phosphatidate propyl]malate 6-phosphate 5-phosphate L-allo-threonine ala acetamide 1,2-diol synthase: dihydroxybenzoate SP_RS11375 subunit alpha: SP_RS05810 reductase: SP_RS05815 SP_RS04065 SP_RS04055 diphosphate RS08090 6-phosphate synthetase: synthase cytidine cytidylate UMP xanthine 1-acyl-sn-glycerol- phosphoglycolate 3-isopropylmalate glucose-6- ribitol-5-phosphate dihydrofolate lactaldehyde chorismate SP_RS06740 ribonucleoside- deaminase: dUDP ribonucleoside- purine-nucleoside 2-deoxy-D-ribose 5-phosphate diphosphomevalonate L-allo-threonine alanine amidase: amidase: phosphoglucosamine SP_RS00135 large subunit: kinase: cytidylate kinase: 2-deoxy-D-ribose 4-alpha- beta- maltodextrin 3-phosphate alpha- phosphatase: dehydrogenase: phosphate 1- dehydrogenase: reductase: reductase: mutase: XMP diphosphate SP_RS04130 diphosphate reductase phosphorylase: adenine lysozyme: alpha-galactosidase: decarboxylase: dehydrogenase: aminotransferase: SP_RS11315 SP_RS11315 mutase: SP_RS07685 3-dehydroquinate SP_RS04365 SP_RS07905 UDP kinase: SP_RS04800 SP_RS07905 5-phosphate glucanotransferase: fructofuranosidase: phosphorylase: acyltransferase: galactosidase: SP_RS00530 SP_RS06130 dehydrogenase: SP_RS06225 SP_RS07745 SP_RS11005 SP_RS06360 reductase: subunit alpha: SP_RS05810 SP_RS04085 C1 Compound Utilization phosphoribosyltransferase: SP_RS03275 SP_RS09430 SP_RS01875 SP_RS09600 SP_RS10035 adenylo-succinate [+ 2 isozymes] nucleoside-diphosphate UMP kinase: SP_RS04670 xanthine 2-deoxyribose-5- SP_RS10740 SP_RS08910 SP_RS10735 1-[18-hydroxyoeoyl]-2-SP_RS08010 SP_RS09430 6-(methylthio)- SP_RS06090 D-ribitol 5- pyrazine-2- RS01620 D-glucosamine PRPP biosynthesis I SP_RS05815 2'-deoxyuridine dCDP and Assimilation SP_RS07775 glycolate 6-phospho D- a 7,8-dihydrofolate (indol-3-yl)acetate (R)-lactaldehyde prephenate RS05250 3-dehydroquinase: xanthosine-5'- inosine-5'-phosphate biosynthesis I kinase: SP_RS09845 dCDP 2-deoxyribose- phosphate aldolase: IPP [18-hydroxy-lioleoyl]-sn 2-oxohexanoate phosphate aminoacetone pyruvate carboxylate 1-phosphate phosphate:L- ribonucleoside- UDP xanthine urate glucono-1,5-lactone aroD adenylosuccinate carbamoyl UDP kinase: dUTP 5-phosphate SP_RS04125 formate assimilation into 5,10- a plant soluble N-acetyl-D- a N-acetylmuramoyl- a non galactosylated α-D- -glycerol 3-phosphate bifunctional N- D-ribose 5- glutamine asp diphosphate thymidine UDP kinase: SP_RS04800 phosphoribosyltransferase: maltose α-D-galactose β-D-fructofuranose a glycoside maltotetraose α-D-galactose D-gluconate 3-dehydroquinate lyase: SP_RS00320 phosphate SP_RS04800 UDP kinase: SP_RS04800 aldolase: methylenetetrahydrofolate AICAR heteroglycan glucosamine pentapeptide- galactose acceptor glucopyranose acetylglucosamine- phosphate amido-ligase reductase kinase: AIR deoxyuridine nucleoside-diphosphate SP_RS09165 nitrite RS05965 nitrite ribose-phosphate dehydratase: nucleoside- nucleoside-diphosphate SP_RS04125 diphosphoundecaprenol 1-phosphate 1-phosphate (AMP-forming) subunit alpha: SP_RS05055 5'-triphosphate kinase: SP_RS09845 acetaldehyde D-glyceraldehyde 3-phosphate formate formate RS02460 pyrophosphokinase SP_RS06770 thymidine diphosphate 5-(carboxyamino) kinase: SP_RS09845 formate uridyltransferase/ : SP_RS07100 AMP aspartate SP_RS05810 nucleotidohydrolase: D-glyceraldehyde 1: SP_RS00175 carbamoyltransferase: kinase: imidazole ribonucleotide dCTP UTP XMP acetaldehyde acetaldehyde formate--tetrahydrofolate glucosamine- 3-dehydroshikimate dUMP SP_RS00145 3-phosphate pyrimidine 1915 967 D-ribulose α-D-glucopyranose D-mannitol [+ 2 isozymes] dCDP thymidine SP_RS09845 synthase: SP_RS00310 ligase: SP_RS06025 galactinol D-glucopyranose maltotetraose isoprimeverose a pseudouridine a ribonucleoside a single a cytosine a [protein] C-terminal a O- 3-[(4'-methylthio) α-D-galactose 1-phosphate adenylate SP_RS06260 CTP synthetase: dehydrogenase ribonucleosides D-ononitol a 5S rRNA precursor putrescine a uridine in tRNA 5-phosphate 3-ethylmalate 1-phosphate choline ethylene glycol 1-phosphate acetamide RS10190 PRPP GMP kinase: dUMP acetaldehyde an N 10 -formyltetrahydrofolate in 23S rRNA triphosphate in 16S rRNA S-farnesyl-L-cysteine sialoglycoprotein butyl]malate acetyltransferase: shikimate shikimate kinase: thymidylate dCTP N5-CAIR (acetylating): degradation 23S rRNA stranded DNA 16S rRNA isoprenylcysteine tRNA UDP kinase: SP_RS05055 SP_RS02435 dehydrogenase spermidine 3-isopropylmalate ribitol-5-phosphate 3-isopropylmalate sugar- galactokinase: lactaldehyde sugar- RS04330 SP_RS04900 dehydrogenase: dehydrogenase: SP_RS01115 synthase: thymidylate synthase: SP_RS10245 cytidine (pseudouridine(1915)- (cytosine(967)-C(5)) carboxyl O-sialoglycoprotein dihydrouridine choline kinase: amidase: guanylate N-carbamoyl- SP_RS04800 CTP (acetylating): bifunctional galactosyl 4-alpha- acetyltransferase: dehydrogenase: dehydrogenase: dehydrogenase: phosphatase: SP_RS09195 reductase: phosphatase: α SP_RS06745 SP_RS06745 SP_RS03285 5-(carboxyamino) SP_RS03285 cytidine deaminase: ribonuclease M5: alpha-xylosidase: N(3))-methyltransferase -methyltransferase: methyltransferase: endopeptidase: synthase DusB: SP_RS06220 SP_RS11315 N-acetyl- -D- kinase: L-aspartate purine ribonucleosides degradation acetyl-CoA methylenetetrahydrofolate transferase: glucanotransferase: DNA primase: SP_RS05060 SP_RS06130 SP_RS06225 SP_RS06130 SP_RS06330 SP_RS11005 SP_RS06330 nucleoside- dCMP imidazole ribonucleotide superpathway of 5-aminoimidazole SP_RS10245 SP_RS10535 SP_RS10000 SP_RS01520 RlmH: SP_RS11445 SP_RS08580 SP_RS11190 SP_RS00770 SP_RS11180 α glucosamine SP_RS08600 ADP dTMP pyrimidine dehydrogenase/ SP_RS10740 an N 3 - SP_RS05300 a [protein] C-terminal 7-(methylthio)-2- D-ribitol 5- -D-galactose RS10605 shikimate dihydroorotase: diphosphate mutase: SP_RS00305 ribonucleotide biosynthesis SP_RS06685 a 5-methylcytosine 967 N-acetylputrescine a 5,6-dihydrouridine 2-oxovalerate D-glucopyranose phosphocholine glycolaldehyde D-mannitol acetate 1-phosphate deoxycytidylate ribonucleosides salvage I acetyl-CoA cytidine deaminase: 1915 phosphate 1-phosphate thymidylate kinase: adenine and methenyltetrahydrofolate methylpseudouridine S-farnesyl-L- a peptide oxoheptanoate RS09325 SP_RS05755 kinase: deaminase: guanine and asp SP_RS04130 in 16S rRNA in tRNA bifunctional N- shikimate GDP CAIR SP_RS04620 PRPP adenosine salvage I cytidine adenosine cyclohydrolase: SP_RS04035 α in 23S rRNA cysteine methyl ester SP_RS09845 SP_RS03645 guanosine salvage uridine D-galactosylononitol myo-inositol maltose maltotriose a mature 5S-rRNA a double-stranded D-glucopyranose -D-xylopyranose ssDNA/pppN(pN) acetylglucosamine- UDP-α-D-galactose kinase: ATP synthase ribonucleoside- (S)-dihydroorotate amidophosphoribosyltransferase: oligonucleotide SP_RS06715 epsilon chain: dTMP dTDP pyrimidine-nucleoside a 5,10-methenyltetrahydrofolate hybrid 1-phosphate biosynthesis diphosphate dCTP dUMP phosphoribosylaminoimidazolesuccinocarboxamide SP_RS00275 cytidine adenosine n -1 SP_RS07420 thymidylate UDP kinase: SP_RS04800 adenosine phosphorylase: deoA RS03915 uridyltransferase/ shikimate 3- UDP kinase: ribonucleoside- reductase: dihydroorotate guanosine synthase: SP_RS00265 amidophosphoribosyltransferase: deaminase: deaminase: bifunctional RS08690 UDP-α-D-glucose thymidylate kinase: purine-nucleoside α glucosamine- phosphate SP_RS04800 diphosphate [+ 12 isozymes] SP_RS05815 dehydrogenase purine-nucleoside nucleoside-diphosphate SP_RS11270 SP_RS10535 CMP SP_RS06635 uracil methylenetetrahydrofolate UDP-Galf octyl -D- 2-amino-6-[1-hydroxyethyl]- (S)-2,3,4,5- a 7,8-dihydro-8- an organic 3-[(6'-methylthio) (2R,3S)-3- a debranched a monocarboxylic D-glucopyranose a large- D-sorbitol synthase: SP_RS04620 phosphorylase: maltose maltohexaose guanosine 2251 in 23S rRNA long chain roseoflavin spermine 2-hydroxyisobutyramide a sugar phosphate acrylamide 1-phosphate UDP-glucose nucleoside- reductase: ribonucleoside- electron phosphorylase: kinase: SP_RS09845 5-phospho-β-D-ribosylamine cytidine dehydrogenase/ glucopyranoside 7-methyl-7,8-dihydropterin tetrahydrodipicolinate oxoguanine in DNA hydroperoxide hexyl]malate isopropylmalate α-limit dextrin acid amide 6-phosphate branched glucan 6-phosphate 3-phosphoshikimate 1- SP_RS03285 SAICAR SP_RS04085 polyphosphate acetyltransferase: 4-epimerase: diphosphate SP_RS05815 diphosphate transfer subunit: dTDP SP_RS04085 dTTP deaminase: xanthosine adenosine inosine guanosine methenyltetrahydrofolate bifunctional dihydroneopterin 4-hydroxy- 23S rRNA bifunctional riboflavin spermidine 3-isopropylmalate 3-isopropylmalate maltodextrin sugar- sugar- sugar- predicted SP_RS04900 carboxyvinyltransferase: dTMP purine-nucleoside alkylhydroperoxidase: kinase/FMN amidase: amidase: pullulanase: amidase: SP_RS07925 kinase: ribonucleoside- ATP reductase SP_RS04775 purine-nucleoside phosphoribosylamine-- SP_RS04130 cyclohydrolase: SP_RS04035 beta-1,6- aldolase/2-amino-4-hydroxy-6- 4-alpha- tetrahydrodipicolinate (guanosine(2251)-2'- exopolyphosphatase: acetyltransferase: dehydrogenase: dehydrogenase: phosphorylase: phosphatase: phosphatase: phosphatase: ABC RS06520 SP_RS06720 UDP kinase: adenylosuccinate phosphorylase: formamidopyrimidine- SP_RS02025 adenylyltransferase: SP_RS11315 SP_RS11315 SP_RS01315 SP_RS11315a sugar a sugar UDP-N-acetyl- [+ 2 isozymes] 5-enolpyruvoyl- SP_RS09845 diphosphate subunit alpha: PRPP thymidylate phosphorylase: glycine ligase: SP_RS00300 S-methyl-5'-thioadenosine galactofuranosyltransferase: hydroxymethyldihydropteridine glucanotransferase: reductase: SP_RS07670 O)-methyltransferase SP_RS08750 SP_RS05060 SP_RS06130 SP_RS06130 SP_RS10735 SP_RS06330 SP_RS06330 SP_RS06330 transporter α UDP-α-D-galactose orotate SP_RS04800 lyase: SP_RS00320 SP_RS04065 DNA glycosylase: SP_RS05495 α -D-glucosamine shikimate 3- reductase SP_RS05810 kinase: SP_RS04065 uridine purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside degradation IV a 5,10-methylenetetrahydrofolate SP_RS08755 [1-(2-amino-7-methyl-4-oxo-diphosphokinase: SP_RS01435 SP_RS10740 (2S,4S)-4-hydroxy-2,3,4,5- RlmB: SP_RS07160 9-(methylthio)- 4-methyl-2- -D-glucopyranose 2-hydroxy-2- a long-linear of a sugar nucleoside- GAR adenine 2-O-methylguanosine 2251 SP_RS04810 an alcohol long chain roseoflavin N 1 -acetylspermine a sugar a monocarboxylate D-glucopyranose α-D-glucan D-sorbitol acrylate phosphate subunit alpha: SP_RS04620 guanine AICAR phosphorylase: phosphorylase: phosphorylase: phosphorylase: 7,8-dihydro-3H-pteridin- tetrahydrodipicolinate 2-oxononanoate oxopentanoate 1-phosphate methylpropanoate orotate diphosphate CMP uridine kinase: S-methyl-5'- octyl β-1,6-D- UDP in 23S rRNA polyphosphate 5'-phosphate RS02725 chorismate GTP SP_RS05810 phosphoribosylglycinamide phosphoribosylglycinamide SP_RS04065 SP_RS04085 SP_RS04085 SP_RS04085 α 6-yl)]ethyl diphosphate RS00380 phosphoribosyltransferase: dTDP kinase: phosphorylation adenine SP_RS05935 thioadenosine galactofuranosyl- - maltoheptaose D-glucopyranose 7,8-dihydro- an apurinic site synthase: dADP xanthine bifunctional formyltransferase: formyltransferase: purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside 5'-methylthioadenosine/ SP_RS03430 SP_RS09845 phosphoribosyltransferase: UMP D-glucopyranoside 8-oxoguanine within DNA SP_RS06735 UDP kinase: phosphoribosyltransferase: phosphoribosylaminoimidazolecarboxamide CMP SP_RS00310 SP_RS00285 phosphorylase: phosphorylase: phosphorylase: phosphorylase: S-adenosylhomocysteine SP_RS04800 SP_RS09165 formyltransferase/inosine monophosphate cytidylate SP_RS07775 dGDP UDP kinase: dTTP SP_RS04085 SP_RS04065 SP_RS04065 SP_RS04065 nucleosidase: chorismate orotidine 5'- cyclohydrolase: SP_RS00295 kinase: FGAR SP_RS04800 nucleoside- hypoxanthine-guanine SP_RS04915 (R)-4'- an N-acetyl-β- 38- β RS12345 phosphate SP_RS07905 AMP D-glucopyranose maltopentaose maltotriose a glucan a double an α-limit dextrin (R)-mevalonate a uridine a kanamycin L-rhamnulofuranose glycerol -L-galactose xylan D-altropyranose uridine pullulan RS02565 nucleoside- diphosphate phosphoribosyltransferase: α-D-ribose- MTR phosphopantothenoyl- carboxynorspermidine D-hexosaminide deethylsimazine 4-guanidinobutyramide prephenate UDP kinase: FAICAR CDP phosphoribosylformylglycinamidine stranded DNA 5-phosphate 40 in tRNA 1-phosphate SP_RS04800 diphosphate orotidine-5'- kinase: SP_RS00060 1-phosphate L-cysteine exodeoxyribonuclease carboxynorspermidine 4-alpha- tRNA aminoglycoside N-ethylammeline glycerol sugar- prephenate alpha- L-fucose uridine kinase: SP_RS09845 synthase: SP_RS00270 rhamnulokinase: amidase: pullulanase: kinase: phosphate bifunctional UDP kinase: phosphopentomutase: 4-alpha- phosphopantothenoylcysteine 4-alpha- V subunit alpha: decarboxylase: beta-N- glucanotransferase: phosphomevalonate pseudouridine(38- phosphotransferase: chlorohydrolase: dehydrogenase: phosphatase: dehydratase: xylosidase: isomerase: SP_RS05935 nucleoside- SP_RS11055 SP_RS11315 SP_RS01315 SP_RS09845 decarboxylase: dTTP GMP phosphoribosylaminoimidazolecarboxamide SP_RS04800 SP_RS04055 glucanotransferase: decarboxylase: SP_RS06035 glucanotransferase: SP_RS01990 SP_RS04550 acetylhexosaminidase: SP_RS10740 kinase: SP_RS01880 40) synthase SP_RS02700 SP_RS11870 SP_RS01230 SP_RS06330 SP_RS06710 SP_RS01520 SP_RS11010 diphosphate FGAM α UMP RS02235 RS00290 SP_RS03425 formyltransferase/inosine monophosphate nucleoside- Amino Acid Degradation SP_RS10740 SP_RS10740 SP_RS00325 a -limit dextrin TruA: SP_RS07880 a kanamycin L-rhamnulose 2-oxo-3- α kinase: D-ribose 5- (R)-mevalonate a pseudouridine 38- dihydroxyacetone L-galactopyranose -D-xylopyranose keto-D-psicose maltotriose dATP cyclohydrolase: SP_RS00295 diphosphate 4'-phosphopantetheine a 5'-phosphooligonucleotide norspermidine with short branches 3'-phosphate 1-phosphate N-ethylammeline 4-guanidinobutanoate SP_RS09845 UMP phosphoribosylformylglycinamidine phosphate diphosphate 40 in tRNA phenylpropanoate kinase: cyclo-ligase: SP_RS00280 L-serine an N-acetyl-β- L-glutamine L-glutamate dGTP IMP SP_RS09845 degradation maltose maltotetraose a glucan D-glucopyranose an alcohol D-hexosamine RS04950 AIR degradation I degradation I RS08440 CTP ser L-cysteine L-serine degradation II gln Glu L-aspartate CTP synthetase: dehydratase, glutamate degradation I SP_RS02435 gln RS04025 gln RS09870 iron-sulfur- cys dehydrogenase: dependent [+ 4 isozymes] SP_RS06400 cysteine asp Glu 2-oxoglutarate subunit beta: desulfhydrase: aspartate RS03925 2-aminoprop-SP_RS00540 2-aminoprop-SP_RS07505 RS05275 aminotransferase: 2-enoate 2-enoate SP_RS07605 aspartate L-glutamate aminotransferase: degradation X RS02275 RS02625 SP_RS08935 2-iminopropanoate 2-iminopropanoate oxaloacetate Glu glutamate dehydrogenase: RS09815 RS09745 SP_RS06400 pyruvate pyruvate 2-oxoglutarate a branched- N-acetyl-α-D- chain an amino an amino an amino galactosamine RS03175 putrescine amino acid an RS03845 D-mannose D-mannose acid acid acid phosphate phosphate D-fructose D-fructose D-fructose a sugar 6- 1-phosphate spermidine ferrichrome N-acetyl-α-D- an L-sorbose 1-phosphate a branched- a branched- a β- a β- a maltodextrin oligopeptide 6-phosphate 6-phosphate an amino an amino an amino an amino an amino an amino 1-phosphate 1-phosphate 1-phosphate phosphate a polar putrescine glucosamine D-trehalose D-mannose D-fructose 1-phosphate D-mannose D-glucose 6- D-glucose 6- 3,5- 3,5- chain chain glucoside 6- glucoside 6- a C4- a C4- D-fructose D-fructose D-fructose a sugar 6- a sugar 6- galactitol 1- a nicotinamide spermidine phosphonate a nucleotide a macrolide queuosine acid acid acid acid acid acid an antibiotic an antibiotic phosphate phosphate amino acid spermidine a drug 6-phosphate 6-phosphate 6-phosphate D-mannose 6-phosphate 6-phosphate phosphate phosphate dimethoxytoluene dimethoxytoluene amino acid amino acid phosphate phosphate phosphate dicarboxylate dicarboxylate 1-phosphate 1-phosphate 1-phosphate phosphate phosphate phosphate mononucleotide a xenobiotic predicted uracil predicted RS00515 predicted predicted predicted predicted ABC predicted predicted predicted predicted predicted predicted predicted predicted predicted predicted PEP-driven predicted ATP-driven ABC PEP-driven PEP-driven transporter ABC ABC ABC ABC ABC PEP-driven PEP-driven PEP-driven PEP-driven ABC transporter ATP-driven RS03450 RS00520 RS05400 transporter RS09055 RS06800 RS02880 RS05525 RS03215 RS02685 RS08045 RS02980 RS06295 RS09930 RS08285 RS03680 RS00630 RS05745 RS05295 RS02525 RS08160 transporter RS01580 RS09350 RS05020 RS02040 transporter RS01390 transporter RS00340 RS03710 RS08320 RS07110 RS01345 RS00755 RS03070 of a transporter RS00765 RS04965 RS03045 RS06835 RS06080 RS03475 transporter transporter RS07660 RS03120 RS04970 RS10630 RS02445 transporter transporter RS04465 RS08520 RS02855 RS10210 RS02030 RS04325 transporter transporter RS05885 transporter RS11665 transporter RS01210 RS10235 RS06305 transporter of of N-acetyl- RS03165 RS09225 transporter RS03480 RS02955 RS06045 RS01350 RS04575 RS07870 RS10925 RS09670 RS07035 RS04895 RS04470 RS06540 RS05135 RS00705 RS01485 RS02365 RS02560 RS05700 RS04300 RS09170 RS02640 RS05500 RS03250 RS09395 RS08235 RS00635 RS10175 RS02600 RS08695 RS07695 RS12515 of spermidine/ of ferrichrome of D-mannose of D-mannose branched- of an of an of an of phosphate of phosphate of D-fructose of D-fructose of D-fructose of a sugar a maltodextrin alpha-D- of an putrescine chain amino acid amino acid amino acid galactosamine oligopeptide a drug amino acid a xenobiotic

N-acetyl-α-D- L-sorbose a branched- a branched- a branched- N-acetyl-α-D- putrescine putrescine trehalose D-mannose D-mannose D-mannose D-mannose D-glucose D-glucose 3,5- 3,5- an amino an amino an amino an amino an amino an amino an amino an amino an amino a β-glucoside a β-glucoside a C4- a C4- D-fructose D-fructose D-fructose D-fructose D-fructose D-fructose a sugar a sugar a sugar a maltodextrin galactitol a nicotinamide an a polar spermidine phosphonate a nucleotide a macrolide ferrichrome glucosamine queuosine D-fructose chain chain chain an antibiotic an antibiotic phosphate phosphate phosphate phosphate uracil galactosamine spermidine spermidine dimethoxytoluene dimethoxytoluene acid acid acid acid acid acid acid acid acid dicarboxylate dicarboxylate mononucleotide oligopeptide amino acid D-mannose amino acid amino acid amino acid phosphate This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.