An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000295435-HmpCyc: Enterococcus faecium ERV1 Cellular Overview Connections between pathways are omitted for legibility. a basic uracil putrescine a pyrimidine an inorganic a C4- N-acetyl-α-D- a nicotinamide an D-cellobiose D-cellobiose D-cellobiose a sugar a sugar a sugar (RS)-malate phosphonate a nucleotide ferrichrome sucrose amino acid galactitol lactose lactose D-cellobiose D-cellobiose spermidine nucleoside anion dicarboxylate glucosamine mononucleotide oligopeptide lactose lactose lactose

predicted predicted PEP-driven PEP-driven RS06030 RS11360 RS09330 RS02840 RS06640 RS00260 RS00020 RS05885 RS06875 RS07605 RS10680 RS10105 RS04720 RS08420 RS12355 RS00815 RS02680 RS00085 RS07115 RS02340 RS02345 RS13170 transporter RS12390 transporter of D- of a sugar cellobiose uracil a sugar 6- a sugar 6- putrescine a pyrimidine an inorganic sucrose 6 G a C4- N-acetyl-α-D- galactitol 1- a nicotinamide an lactose 6'- D-cellobiose 6'-phosphate D-cellobiose 6'-phosphate lactose 6'- D-cellobiose 6'-phosphate D-cellobiose (RS)-malate phosphonate a nucleotide ferrichrome a basic phosphate phosphate spermidine nucleoside anion -phosphate dicarboxylate glucosamine phosphate mononucleotide oligopeptide phosphate lactose 6'-phosphate lactose 6'-phosphate phosphate lactose 6'-phosphate 6'- a sugar 6- amino acid 6-phosphate D-cellobiose phosphate phosphate 6'- phosphate

Carbohydrate Degradation Amine and Polyamine Degradation Metabolic Regulator Macromolecule Modification tRNA processing superpathway of pyrimidine Nucleoside and Nucleotide Biosynthesis a glycopeptide- 5'-deoxy-5'- a (3R)-3- a (3R)-3- a (3R)-3- a (3R,11Z)-3- superpathway of pyrimidine ribonucleosides salvage superpathway of guanosine Biosynthesis 4 deoxyribonucleotides de novo biosynthesis inosine-5'-phosphate biosynthesis I purine deoxyribonucleosides salvage D-galactose degradation I (Leloir pathway) D-galactose degradation V (Leloir pathway) superpathway of N-acetylglucosamine, a palmitoyl-[acp] a malonyl-[acp] a palmitoleoyl-[acp] a malonyl-[acp] D-mannosyl-N a purine fluoroadenosine hydroxyhexacosanoyl- hydroxydocosanoyl- hydroxyglutaryl- hydroxyoctadec- 3'-AMP nucleotides de novo biosynthesis I a polycistronic N-acetylmannosamine and N- 3-oxoacyl-[acyl-carrier- beta-ketoacyl-[acyl-carrier- -(N-acetyl-D- ribonucleoside purine-nucleoside [acp] 3-hydroxyacyl-[acyl- [acp] 3-hydroxyacyl-[acyl- [acp] methyl ester3-hydroxyacyl-[acyl- 11-enoyl-[acp]3-hydroxyacyl-[acyl- multifunctional 2',3'- cytidine ppGpp biosynthesis tRNA precursor acetylneuraminate degradation purine-nucleoside AIR β β protein] reductase: protein] synthase II: glucosaminyl) phosphorylase: carrier-protein] carrier-protein] carrier-protein] carrier-protein] cyclic-nucleotide 2'- gln hydrogencarbonate -D-galactose -D-galactose mannosyl-glycoprotein phosphorylase: 5-(carboxyamino)imidazole 2'-deoxyguanosine 2'-deoxyadenosine N-acetylneuraminate HMPREF1361_RS05580 HMPREF1361_RS05585 -asparagine HMPREF1361_RS02415 dehydratase FabZ: dehydratase FabZ: dehydratase FabZ: dehydratase FabZ: phosphodiesterase/ cytidine deaminase: IMP 2 endo-beta-N- ribonucleotide synthase: deoxynucleoside kinase: deoxynucleoside kinase: pppGpp galactose-1-epimerase: galactose-1-epimerase: HMPREF1361_RS02415 purine-nucleoside carbamoyl- HMPREF1361_RS02385 GTP pyrophosphokinase: beta-ketoacyl-[acyl-carrier- 3-oxoacyl-[acyl-carrier- acetylglucosaminidase: HMPREF1361_RS03665 HMPREF1361_RS03665 HMPREF1361_RS05595 HMPREF1361_RS03665 5'-nucleotidase/ HMPREF1361_RS06525 HMPREF1361_RS07960 HMPREF1361_RS07960 HMPREF1361_RS13610 HMPREF1361_RS13610 purine-nucleoside phosphorylase: phosphate synthase: HMPREF1361_RS04460 N-acetyl-D- protein] synthase II: protein] reductase: HMPREF1361_RS08445 3-hydroxyacyl-[acyl- 3-hydroxyacyl-[acyl- 3-hydroxyacyl-[acyl- 3-hydroxyacyl-[acyl- 3'-nucleotidase: CMP IMP dehydrogenase: N5-CAIR a tRNA precursor [+ 2 isozymes] [+ 2 isozymes] phosphorylase: HMPREF1361_RS02420 HMPREF1361_RS06010 uridine [+ 2 isozymes] [+ 2 isozymes] bifunctional (p)ppGpp exoribonuclease: mannosamine HMPREF1361_RS05585 HMPREF1361_RS05580an (11Z)-3- carrier-protein] carrier-protein] carrier-protein] carrier-protein] HMPREF1361_RS10010 HMPREF1361_RS09010 dGMP dAMP with a 5' extension a 3-oxooctadecanoyl- mannosyl-glycoprotein HMPREF1361_RS02420 5-fluoro-5- HMPREF1361_RS06015 (d)CMP kinase: 5-(carboxyamino)imidazole synthetase/guanosine- HMPREF1361_RS03375 α-D-galactose α-D-galactose acyl-carrier protein acyl-carrier protein oxooctadec- α-D-ribose- dehydratase FabZ: dehydratase FabZ: dehydratase FabZ: dehydratase FabZ: HMPREF1361_RS12605 guanosine 3'-diphosphate and a long 3' trailer a tRNA precursor with [acp] endo-beta-N- a purine base deoxy-D-ribose adenine adenosine bifunctional pyr operon inosine-uridine preferring ribonucleotide mutase: 3',5'-bis(diphosphate) 3'- 11-enoyl-[acp] 1-phosphate HMPREF1361_RS05595 HMPREF1361_RS05595 a (2E)- HMPREF1361_RS03665 a (2E,11Z)-HMPREF1361_RS05595 carbamoyl 5'-triphosphate 3'- a 5' extension and acetylglucosamidase: 1-phosphate a (2E)-hexacos- a (2E)-docos- asp transcriptional regulator/uracil nucleoside hydrolase: CDP XMP HMPREF1361_RS06530 pyrophosphohydrolase: galactokinase: galactokinase: a glycopeptide- N-acetyl-D- enoylglutaryl- octadeca-2,11- phosphate diphosphatase: a short 3' extension N-acetyl-D- HMPREF1361_RS08120 2-enoyl-[acp] 2-enoyl-[acp] phosphoribosyltransferase HMPREF1361_RS03350 HMPREF1361_RS04250 RNase BN ribonuclease: ribonuclease PH: HMPREF1361_RS13615 HMPREF1361_RS13615 D-mannosyl- glucosamine- [acp] methyl ester dienoyl-[acp] ribonuclease P mannosamine 4 aspartate xanthosine-5'-phosphate:L- CAIR HMPREF1361_RS04250 HMPREF1361_RS03695 N -N-acetyl- PyrR: HMPREF1361_RS06035 HMPREF1361_RS03375 protein component: α-D-galactose α-D-galactose 6-phosphate asparagine carbamoyltransferase uridine kinase: uracil glutamine amido- UDP-α-D-glucose UDP-α-D-glucose putative N- D-glucosamine uracil phosphoribosylaminoimidazolesuccinocarboxamide dGDP dADP HMPREF1361_RS14885 1-phosphate 1-phosphate catalytic subunit: HMPREF1361_RS11985 ligase (AMP-forming): acetylmannosamine-6- phosphoribosyltransferase: synthase: HMPREF1361_RS06510 ribonuclease P HMPREF1361_RS06025 HMPREF1361_RS02355 phosphate 2-epimerase: a (3R)-3- a (3R,5Z)-3- 1939 HMPREF1361_RS10350 UDP kinase: UDP kinase: a tRNA precursor protein component: a (4Z)-hexadec- a uracil GTP ppGpp HMPREF1361_RS09670 an acetyl-[acp] a malonyl-[acp] a malonyl-[acp] a purine a purine 2'- glycerophosphoserine hydroxytetracosanoyl- MEP CTP hydroxydodec- 3'-GMP N-carbamoyl- UDP kinase: SAICAR HMPREF1361_RS00575 HMPREF1361_RS00575 with a 5' extension HMPREF1361_RS08950 4-enoyl-[acp] arsenate in 23S rRNA GMP N-acetyl-D- beta-ketoacyl-[acyl-carrier- beta-ketoacyl-[acyl-carrier- ribonucleoside deoxyribonucleoside glycerophosphoryl diester [acp] 3-hydroxyacyl-[acyl- 2-C-methyl-D- 5-enoyl-[acp]3-hydroxyacyl-[acyl- 23S rRNA multifunctional 2',3'- L-aspartate HMPREF1361_RS00575 nucleoside- nucleoside- purine-nucleoside purine-nucleoside adenylosuccinate lyase: a tRNA precursor with glucosamine protein] synthase II: protein] synthase II: phosphodiesterase: carrier-protein] erythritol 4-phosphate carrier-protein] (uracil(1939)-C(5))- cyclic-nucleotide 2'- nucleoside- diphosphate kinase: diphosphate kinase: ribonuclease: phosphorylase: phosphorylase: dihydroorotase: UMP HMPREF1361_RS06520 UDP kinase: a short 3' extension 6-phosphate HMPREF1361_RS05585 HMPREF1361_RS05585 HMPREF1361_RS10995 dehydratase FabZ: cytidylyltransferase: dehydratase FabZ: methyltransferase RlmD: phosphodiesterase/ diphosphate kinase: guanylate kinase: HMPREF1361_RS12095 HMPREF1361_RS12095 HMPREF1361_RS08950 HMPREF1361_RS02415 HMPREF1361_RS02415 HMPREF1361_RS06020 HMPREF1361_RS00575 N-acetylglucosamine-6- glycerophosphodiester HMPREF1361_RS03665 HMPREF1361_RS00280 HMPREF1361_RS05595 HMPREF1361_RS05470 5'-nucleotidase/ UMP kinase: HMPREF1361_RS12095 HMPREF1361_RS08675 ribonuclease PH: 3-oxoacyl-[acyl-carrier- 3-oxoacyl-[acyl-carrier- AICAR nucleoside- phosphate deacetylase: purine-nucleoside purine-nucleoside phosphodiesterase: 23S rRNA 3'-nucleotidase: (S)-dihydroorotate HMPREF1361_RS05750 dGTP dATP GTP pyrophosphokinase: HMPREF1361_RS03695 HMPREF1361_RS06645 protein] reductase: protein] reductase: phosphorylase: 3-hydroxyacyl-[acyl- 2-C-methyl-D- 3-hydroxyacyl-[acyl- diphosphate kinase: bifunctional (p)ppGpp phosphorylase: HMPREF1361_RS07510 (uracil(1939)-C(5))- HMPREF1361_RS10010 (d)CMP kinase: bifunctional HMPREF1361_RS04460 HMPREF1361_RS05580 HMPREF1361_RS05580a (6Z)-3- HMPREF1361_RS02420 carrier-protein] erythritol 4-phosphate carrier-protein] GDP HMPREF1361_RS12095 synthetase/guanosine- D-glucosamine 2-deoxy-α- HMPREF1361_RS02420 sn-glycerol methyltransferase RlmD: dihydroorotate oxidase: HMPREF1361_RS12605 phosphoribosylaminoimidazolecarboxamide queuosine biosynthesis an acetoacetyl-[acp] acyl-carrier protein acyl-carrier protein oxooctadec- ser dehydratase FabZ: cytidylyltransferase: dehydratase FabZ: 3',5'-bis(diphosphate) 3'- an uncharged tRNA 6-phosphate ribose-1-arsenate a purine base D-ribose 1- a purine base 3-phosphate HMPREF1361_RS00945 guanosine HMPREF1361_RS09530 formyltransferase/IMP cyclohydrolase 6-enoyl-[acp] HMPREF1361_RS05595 4-(cytidine 5'-HMPREF1361_RS00285 HMPREF1361_RS03665 a 5- UDP pyrophosphohydrolase: phosphate a (2E)-tetracos- a (2E,5Z)-dodeca- 1939 PurH: HMPREF1361_RS06475 preQ diphospho)-2-C- methyluracil UDP kinase: GDP reductase: 0 orotate PRPP UDP kinase: HMPREF1361_RS04250 2-enoyl-[acp] 3,5-dienoyl-[acp] in 23S rRNA HMPREF1361_RS00575 HMPREF1361_RS11220 methyl-D-erythritol HMPREF1361_RS00575 FAICAR α-D-glucosamine orotate nucleoside- GDP 6-phosphate nucleoside- UMP biosynthesis III preQ phosphoribosyltransferase: diphosphate kinase: bifunctional 1 sn-glycero-3- a 2-deoxy-D- a (3R)-3- a (3R)-3- diphosphate kinase: superpathway of pyrimidine deoxyribonucleoside salvage glucosamine-6- a malonyl-[acp] quinoxaline-2- a nucleobase glycerophosphoglycerol a uridine in tRNA DHAP HMPREF1361_RS05990 HMPREF1361_RS12095 dGDP phosphoribosylaminoimidazolecarboxamide Aromatic Compound Glycolysis UDP-glucose-- UDP-glucose-- a malonyl-[acp] aryl-carrier protein phosphoethanolamine ribosyl-base hydroxyoctadecanoyl- hydroxyicosanoyl- IMP HMPREF1361_RS12095 tRNA guanosine(34) UDP-glucose 4- UDP-glucose 4- phosphate deaminase: methyl ester carboxyl adenylate nucleoside tRNA dihydrouridine NAD(P)H-dependent gln hydrogencarbonate formyltransferase/IMP cyclohydrolase Biosynthesis hexose-1-phosphate hexose-1-phosphate beta-ketoacyl-[acyl-carrier- acyl carrier protein: glycerophosphoryl diester glycerophosphodiester [acp] 3-hydroxyacyl-[acyl- [acp] 3-hydroxyacyl-[acyl- orotidine 5'- adenine and 2'-deoxycytidine transglycosylase Tgt: epimerase GalE: epimerase GalE: HMPREF1361_RS11240 deoxyribosyltransferase: synthase DusB: glycerol-3-phosphate multifunctional 2',3'- UTP UDP kinase: PurH: HMPREF1361_RS06475 glycolysis III (from glucose) uridylyltransferase: uridylyltransferase: protein] synthase II: HMPREF1361_RS05570 phosphodiesterase: phosphodiesterase: carrier-protein] carrier-protein] phosphate adenosine salvage III HMPREF1361_RS08080 HMPREF1361_RS07665 HMPREF1361_RS07665 HMPREF1361_RS04960 HMPREF1361_RS03025 dehydrogenase: cyclic-nucleotide 2'- carbamoyl- GTP HMPREF1361_RS00575 Secondary Metabolite Biosynthesis chorismate biosynthesis I a 7-aminomethyl-7- HMPREF1361_RS07670 HMPREF1361_RS07670 F6P HMPREF1361_RS05585 acyl carrier protein: HMPREF1361_RS10995 HMPREF1361_RS07510 dehydratase FabZ: dehydratase FabZ: cytidine deaminase: 2'-deoxycytidine kinase: HMPREF1361_RS10125 phosphodiesterase/ phosphate synthase: 34 α α glycerophosphodiester nucleoside glycerophosphoryl diester HMPREF1361_RS03665 tRNA-dihydrouridine HMPREF1361_RS03665 orotidine-5'-phosphate CTP synthase: nucleoside- IMP HMPREF1361_RS02385 HMPREF1361_RS10610 deazaguanosine D-glucopyranose -D-glucopyranose -D-glucopyranose 3-oxoacyl-[acyl-carrier- HMPREF1361_RS02655 5'-nucleotidase/ HMPREF1361_RS06010 adenine D-erythrose UDP-α-D-galactose UDP-α-D-galactose a quinoxaline-2- phosphodiesterase: deoxyribosyltransferase: phosphodiesterase: synthase: NAD(P)H-dependent decarboxylase: HMPREF1361_RS01245 diphosphate kinase: autoinducer AI-2 biosynthesis I in tRNA 1-phosphate 1-phosphate protein] reductase: 3-hydroxyacyl-[acyl- 3-hydroxyacyl-[acyl- 3'-nucleotidase: HMPREF1361_RS06015 purine-nucleoside superpathway of 4-phosphate AMP carboxyl-[aryl- HMPREF1361_RS07510 HMPREF1361_RS01220 HMPREF1361_RS10995 HMPREF1361_RS08370 glycerol-3-phosphate HMPREF1361_RS05995 HMPREF1361_RS12095 2'-deoxyuridine dCMP tRNA preQ1(34) S- glucokinase: HMPREF1361_RS05580 carrier-protein] carrier-protein] HMPREF1361_RS10010 phosphorylase: adenosine nucleotides 3-deoxy-7- phosphomannomutase/ phosphomannomutase/ a 3-oxoglutaryl- carrier protein] sn-glycerol a 2-deoxy-D- sn-glycerol a 5,6-dihydrouridine dehydrogenase: UMP adenosylmethionine HMPREF1361_RS07640 acyl-carrier protein ethanolamine a nucleobase glycerol dehydratase FabZ: dehydratase FabZ: asp carbamoyl HMPREF1361_RS02420 de novo biosynthesis I (d)CMP kinase: SAM phosphoheptulonate phosphoglucomutase: phosphoglucomutase: [acp] methyl ester 3-phosphate ribosyl-base 3-phosphate in tRNA HMPREF1361_RS03600 inosine phosphate dGTP thymidine kinase: ribosyltransferase- D-glucopyranose C1 Compound Utilization HMPREF1361_RS05595 HMPREF1361_RS05595 UMP kinase: HMPREF1361_RS12605 synthase: HMPREF1361_RS13520 lactose and galactose degradation I HMPREF1361_RS13520 a (2E)-octadec- a (2E)-icos- sn-glycerol purine-nucleoside HMPREF1361_RS10385 isomerase QueA: 6-phosphate and Assimilation HMPREF1361_RS05750 aspartate asp IMP HMPREF1361_RS00985 2-enoyl-[acp] 2-enoyl-[acp] 3-phosphate phosphorylase: [+ 3 isozymes] dCDP HMPREF1361_RS08095 glucose-6- D-glucopyranose D-glucopyranose (d)CMP kinase: CTP carbamoyltransferase adenylosuccinate synthase: thymidine 3-deoxy- lactose 6'- pectin degradation II superpathway of pyrimidine HMPREF1361_RS02415 an epoxyqueuosine 34 6-phosphate 6-phosphate formate assimilation into 5,10- UDP kinase: SAH D-arabino- phosphate phosphate HMPREF1361_RS12605 nucleobases salvage catalytic subunit: adenosine HMPREF1361_RS09100 dUMP in tRNA 6-phospho-beta- methylenetetrahydrofolate adenylo-succinate HMPREF1361_RS00575 heptulosonate isomerase: pgi L-rhamnose degradation I a methyl-esterified an N-formyl-L- DNA combined with a (3R)-3- an [apo BCAA UDP HMPREF1361_RS06025 thymidine kinase: 5'-methylthioadenosine/ galactosidase: a glutaryl-[acp] a (6S)-5- D-glyceraldehyde 5'-chloro-5'- uracil superpathway of 5-aminoimidazole nucleoside- 7-phosphate epoxyqueuosine reductase: homogalacturonan a malonyl-[acp] glu methionylaminoacyl- pyruvate exogenous DNA to form (R)-pantoate hydroxypimeloyl- dehydrogenase adenylosuccinate lyase: thymidylate synthase: HMPREF1361_RS10385 adenosylhomocysteine F6P HMPREF1361_RS02335 pectinesterase: formate methyl ester formyltetrahydrofolate 3-phosphate deoxyadenosine dIDP N-carbamoyl- ribonucleotide biosynthesis adenosine deaminase: diphosphate kinase: D-galactopyranose α-L- 6 bifunctional pyr operon HMPREF1361_RS13430 3-dehydroquinate synthase: HMPREF1361_RS13555 HMPREF1361_RS03885 formate-- beta-ketoacyl-[acyl-carrier- tRNA peptide deformylase: 1-deoxy-D-xylulose-5- a recombinational junctionHolliday junction purine-nucleoside 2-dehydropantoate [acp] methyl ester3-hydroxyacyl-[acyl- E2 protein] N UDP kinase: L-aspartate HMPREF1361_RS05870 HMPREF1361_RS06520 [+ 3 isozymes] HMPREF1361_RS12095 nucleosidase: maltose degradation 6-phosphate rhamnopyranose bifunctional UDP kinase: transcriptional regulator/uracil a queuosine 34 6-phosphofructokinase: a homogalacturonan tetrahydrofolate ligase: protein] synthase II: phosphate synthase: phosphorylase: 2-reductase: carrier-protein] -dihydrolipoyl- HMPREF1361_RS00575 PRPP thymidylate synthase: HMPREF1361_RS05430 HMPREF1361_RS00990 L-rhamnose mutarotase: folylpolyglutamate synthase/ HMPREF1361_RS11930 resolvase RecU: recU dihydrolipoamide HMPREF1361_RS00575 phosphoribosyltransferase in tRNA HMPREF1361_RS09055 HMPREF1361_RS06060 HMPREF1361_RS05585 HMPREF1361_RS14845 HMPREF1361_RS02415 HMPREF1361_RS00735 dehydratase FabZ: L-lysine dihydroorotase: amidophosphoribosyltransferase: HMPREF1361_RS12675 dCTP β HMPREF1361_RS08015 α an N 10 - dihydrofolate synthase: peptide deformylase: Holliday junction dehydrogenase: dUDP nucleoside- PyrR: HMPREF1361_RS06035 AMP maltose -L- galacturan 1,4- - purine-nucleoside 2-dehydropantoate nucleoside- HMPREF1361_RS06020 HMPREF1361_RS06490 inosine S-ribosyl-L-homocysteine 3-dehydroquinate β-D-fructose 1,6- formyltetrahydrofolate 3-oxoacyl-[acyl-carrier- HMPREF1361_RS07290 HMPREF1361_RS08690 1-deoxy-D-xylulose-5- resolvase RuvX: HMPREF1361_RS05595 HMPREF1361_RS04640 diphosphate kinase: uracil maltose phosphorylase: rhamnopyranose galacturonidase: a (6S)-5- a L-methionylaminoacyl- phosphorylase: 2-reductase: diphosphate kinase: UDP kinase: bisphosphate D-tagatofuranose protein] reductase: formate phosphate synthase: resolution of recombinationalHMPREF1361_RS01980 3-hydroxyacyl-[acyl- maltose RS14580 maltose HMPREF1361_RS12095 phosphoribosyltransferase: amidophosphoribosyltransferase: type I 3-dehydroquinate HMPREF1361_RS10835 L-rhamnose isomerase: HMPREF1361_RS03895 bifunctional formyltetrahydrofolate tRNA HMPREF1361_RS02420 HMPREF1361_RS07840 dihydrolipoyl HMPREF1361_RS12095 HMPREF1361_RS00575 (S)-dihydroorotate purine-nucleoside adenylate kinase: S-ribosylhomocysteine β-D-glucopyranose 6-phosphate HMPREF1361_RS05580 HMPREF1361_RS14850 junction formation carrier-protein] HMPREF1361_RS10350 β HMPREF1361_RS03500 dehydratase: HMPREF1361_RS08025 methylenetetrahydrofolate 1-deoxy-D-xylulose 5-chloro-5- dehydrogenase: dITP nucleoside- 5-phospho- - phosphorylase: HMPREF1361_RS02570 guanine and lyase: 5-oxo-L-proline metabolism fructose-1,6-bisphosphate 1-phosphate tagatose-6- D-galactopyranuronate acyl-carrier protein a 3-oxopimeloyl- of two intact strands 2-dehydropantoate dehydratase FabZ: an [apo BCAA UMP dihydroorotate D-ribosylamine HMPREF1361_RS07345 dehydrogenase/ [acp] methyl ester 5-phosphate adenine deoxyribose dehydrogenaseHMPREF1361_RS06405 diphosphate kinase: gln UTP HMPREF1361_RS02420 dTMP guanosine salvage HMPREF1361_RS13705 aldolase, class II: phosphate kinase: keto-L-rhamnulose HMPREF1361_RS03665 predicted an N-terminal beta-phosphoglucomutase: methenyltetrahydrofolate 1-phosphate a (2E)- 6 HMPREF1361_RS12095 UMP kinase: dehydrogenase phosphoribosylamine- purine-nucleoside 3-dehydroshikimate HMPREF1361_RS01250 HMPREF1361_RS12335 E2 protein] N ADP dTMP kinase: AI-2 L-glutaminyl- an N-terminal L- HMPREF1361_RS01790 cyclohydrolase: enoylpimeloyl- ABC HMPREF1361_RS05750 electron transfer subunit: -glycine ligase: phosphorylase: tagatose-6- -lipoyl-L-lysine a sugar a sugar dUTP CTP synthase: HMPREF1361_RS06750 [protein] glutamyl-[protein] beta-phosphoglucomutase: aldehydo-D- HMPREF1361_RS06950 [acp] methyl ester transporter (d)CMP kinase: HMPREF1361_RS06005 HMPREF1361_RS06470 HMPREF1361_RS02415 guanosine shikimate dehydrogenase: phosphate kinase: HMPREF1361_RS01245 triose-phosphate HMPREF1361_RS10840 galacturonate of a sugar dUTP diphosphatase: HMPREF1361_RS12605 orotate PRPP ADP reductase: dTDP purine-nucleoside HMPREF1361_RS00025 HMPREF1361_RS11680 a 5,10- HMPREF1361_RS08500 GAR isomerase: β-D-glucose L-rhamnulofuranose methenyltetrahydrofolate a (3R,7Z)-3- a [lipoyl-carrier CTP hypoxanthine HMPREF1361_RS11220 phosphorylase: glucuronate isomerase: an acyl-[acyl- a nucleoside 4-hydroxy-2- a sugar RS05835 a sugar UDP UDP kinase: HMPREF1361_RS03330 6-phosphate D-tagatofuranose a ribonucleic acid glycochenodeoxycholate 3'-dephospho- a [protein] Ser/Thr a 3-oxoicosanoyl- 6 dUMP orotate HMPREF1361_RS02420 (2R,4S)-2-methyl-2,4- shikimate D-glyceraldehyde HMPREF1361_RS03945 bifunctional a malonyl-[acp] triphosphate ATP oxoglutarate hydroxy-hexadec- protein]-N -[(R) IDP phosphoribosylglycinamide HMPREF1361_RS00575 a [protein] with DHAP 1,6-bisphosphate rhamnulokinase: carrier protein] CoA HPr kinase/phosphorylase: [acp] UDP kinase: phosphoribosyltransferase: xanthine purine-nucleoside dihydroxydihydrofuran-3-one 3-phosphate methylenetetrahydrofolate 3-oxoacyl-[acyl-carrier- DNA-directed RNA choloylglycine hydrolase: bifunctional 2-keto- 7-enoyl-[acp]3-hydroxyacyl-[acyl- -dihydrolipoyl]- formyltransferase: nucleoside- an N-terminal 5- γ tagatose-bisphosphate HMPREF1361_RS08030 D-tagaturonate triphosphoribosyl- 3-oxoacyl-ACP reductase: UDP kinase: thymidylate synthase: HMPREF1361_RS00575 phosphoribosyltransferase: dADP phosphorylase: shikimate kinase: -L-glutamyl glyceraldehyde-3- dehydrogenase/ protein] reductase: polymerase subunit delta: HMPREF1361_RS13095 HMPREF1361_RS03590 4-hydroxyglutarate carrier-protein] L-lysine dihydrolipoyl HMPREF1361_RS05990 HMPREF1361_RS06480 diphosphate kinase: oxo-L-proline glutathione aldolase: L-rhamnulose dephospho-CoA HMPREF1361_RS07985 HMPREF1361_RS00575 HMPREF1361_RS13430 CDP nucleoside- adenine and HMPREF1361_RS06540 HMPREF1361_RS02415 HMPREF1361_RS01010 5-phosphate phosphate dehydrogenase: methenyltetrahydrofolate HMPREF1361_RS05580 HMPREF1361_RS03285 choloylglycine hydrolase: serine/threonine aldolase/2-keto-3-deoxy- dehydratase FabZ: dehydrogenase: a sugar RS10545 a sugar HMPREF1361_RS12095 HMPREF1361_RS11685 1-phosphate synthase MdcB: [+ 2 isozymes] nucleoside- thymidylate synthase: diphosphate kinase: adenosine salvage I FGAR UDP kinase: guanine HMPREF1361_RS03320 cyclohydrolase: HMPREF1361_RS11435 protein kinase: 6-phosphogluconate HMPREF1361_RS05595 HMPREF1361_RS06405 orotidine 5'- hypoxanthine (2R,4S)-2-methyl-2,3,3,4- shikimate 3- pyroglutamyl-peptidase I: beta-ketoacyl-[acyl-carrier- [+ 4 isozymes] 2'-(5''-triphospho-HMPREF1361_RS13300 a (3R)-3- diphosphate kinase: HMPREF1361_RS12675 HMPREF1361_RS12095 HMPREF1361_RS00575 dTTP tagatose-bisphosphate rhamnulose-1- HMPREF1361_RS06950 HMPREF1361_RS08710 aldolase: dihydrolipoamide phosphate phosphoribosyltransferase: adenine salvage tetrahydroxytetrahydrofuran phosphate HMPREF1361_RS00805 protein] synthase II: a ribonucleic acid gly chenodeoxycholate adenine α-D-ribosyl)-3'- hydroxyicosanoyl- 3-hydroxyacyl-[acyl- HMPREF1361_RS12095 phosphoribosylformylglycinamidine nucleoside- xanthine 13-DPG aldolase: phosphate aldolase: D-fructuronate a [protein] (L-serine/L- HMPREF1361_RS08000 dehydrogenase: dTMP dCDP UTP adenosine HMPREF1361_RS03040 3-phosphoshikimate 1- a 5,10- HMPREF1361_RS05585 dephospho-CoA [acp] carrier-protein] a sugar RS13800 a sugar orotidine-5'-phosphate synthase: HMPREF1361_RS06495 diphosphate kinase: phosphoribosyltransferase: HMPREF1361_RS11700 HMPREF1361_RS08020 threonine) phosphate pyruvate glyoxylate a [lipoyl-carrierHMPREF1361_RS04640 ITP purine-nucleoside carboxyvinyltransferase: methylenetetrahydrofolate acyl-carrier protein a 3-oxoacyl-[acp] dehydratase FabZ: dTMP kinase: UDP kinase: CTP synthase: decarboxylase: HMPREF1361_RS06500 HMPREF1361_RS12095 HMPREF1361_RS06540 5-oxo-L-proline phosphoglycerate kinase: D-glyceraldehyde protein]-N 6 - phosphorylase: IMP DHAP (S)-lactaldehyde DHAP HMPREF1361_RS03665 HMPREF1361_RS06750 HMPREF1361_RS00575 HMPREF1361_RS01245 HMPREF1361_RS05995 HMPREF1361_RS06505 adenine HMPREF1361_RS01005 HMPREF1361_RS03325 3-phosphate a (2E,7Z)- lipoyl-L-lysine HMPREF1361_RS02420 guanine and hypoxanthine 5-enolpyruvoyl- hexadeca-2,7- dTDP nucleoside- dATP a sugar RS09335 a sugar CTP purine-nucleoside UMP FGAM xanthine and guanosine salvage II phosphoribosyltransferase: shikimate 3- dienoyl-[acp] diphosphate kinase: 3-phospho-D-glycerate UDP kinase: phosphorylase: xanthosine salvage HMPREF1361_RS03040 phosphate HMPREF1361_RS12095 adenine deaminase: adenine HMPREF1361_RS00575 HMPREF1361_RS02415 phosphoribosylformylglycinamidine chorismate synthase: 2,3- guanosine HMPREF1361_RS04160 phosphoribosyltransferase: glu sucrose degradation III (sucrose invertase) an inactive D-cellobiose a (7Z,10Z,13Z,16Z 1518 a (3R,5Z)-3- a ribonucleoside nucleoside- dCTP adenine cyclo-ligase: HMPREF1361_RS06485 GMP HMPREF1361_RS00995 diphosphoglycerate- sucrose degradation IV (sucrose phosphorylase) adenine / phosphoenol an [HPr]- (4S)-4-hydroxy- a 3-oxopimeloyl- Peptide RS10265 Peptide xanthosine 1519 HMPREF1361_RS05050 SAM ribonucleoside a reduced 6'-phosphate ,19Z)-3-oxodocosa- adenine in 16S rRNA pyruvate L-histidine 2-oxoglutarate hydroxy-tetradec- 2',3'-cyclic IMP diphosphate kinase: dependent 6-phospho-beta- phosphoenolpyruvate- [acp] methyl ester AIR purine-nucleoside sucrose triphosphate flavodoxin 7,10,13,16,19-pentaenoyl-[acp] 16S rRNA (adenine(1518)- bifunctional 2-keto- 5-enoyl-[acp]3-hydroxyacyl-[acyl- phosphatemultifunctional 2',3'- HMPREF1361_RS12095 adenine chorismate phosphoglycerate sucrose anaerobic ribonucleoside- glucosidase: 3-oxoacyl-ACP reductase: -protein 3-oxoacyl-ACP reductase: phosphorylase: hypoxanthine reductase N(6)/adenine(1519)-N(6))- 4-hydroxyglutarate carrier-protein] cyclic-nucleotide 2'- phosphoribosyltransferase: guanine mutase: gpmA triphosphate reductase HMPREF1361_RS04935 HMPREF1361_RS07985 phosphotransferase: HMPREF1361_RS07985 GMP reductase: Peptide RS03790 Peptide dTTP HMPREF1361_RS02415 AMP dimethyltransferase RsmA: aldolase/2-keto-3-deoxy- dehydratase FabZ: phosphodiesterase/ HMPREF1361_RS05050 lipoprotein posttranslational beta-fructofuranosidase: activating protein: [+ 2 isozymes] HMPREF1361_RS05530 [+ 2 isozymes] HMPREF1361_RS06430 xanthine sucrose phosphorylase: [+ 3 isozymes] 6 HMPREF1361_RS102001518 6-phosphogluconate HMPREF1361_RS05595 purine-nucleoside 2-phospho-D-glycerate HMPREF1361_RS10535 HMPREF1361_RS06785an active D-glucopyranose a (3R,7Z,10Z,13Z,16Z N -dimethyladenine an [HPr protein]- a (3R)-3- 5'-nucleotidase/ xanthine modification π aldolase: phosphorylase: phosphoribosyltransferase: HMPREF1361_RS01835 a flavodoxin ribonucleoside D-glucopyranose ,19Z)-3-hydroxydocosa- /N 6 -dimethyladenine 1519 N -phospho- pyruvate hydroxypimeloyl- 3-hydroxyacyl-[acyl- 3'-nucleotidase: AMP phosphoribosyltransferase: phosphopyruvate beta-fructofuranosidase: met 5'-deoxyadenosine 6-phosphate HMPREF1361_RS08000 HMPREF1361_RS02420 HMPREF1361_RS06540 a [prolipoprotein]- semiquinone triphosphate 7,10,13,16,19-pentaenoyl-[acp] in 16S rRNA L-histidine [acp] methyl ester carrier-protein] HMPREF1361_RS10010 GMP a cation RS04370 a cation xanthine HMPREF1361_RS06540 hydratase: α-D-glucopyranose HMPREF1361_RS10580 hypoxanthine L-cysteine β-D-fructofuranose reductase pyruvate glyoxylate dehydratase FabZ: a ribonucleoside hypoxanthine HMPREF1361_RS03335 1-phosphate 3'-phosphate xanthine phosphoribosyltransferase: prolipoprotein HMPREF1361_RS03665 phosphoribosyltransferase: phosphomannomutase/ β-D-fructofuranose D-glucopyranose a (2E,5Z)- phosphoribosyltransferase: HMPREF1361_RS03040 diacylglyceryl transferase: phosphoenolpyruvate tetradeca-2,5- a cation RS00225 a cation HMPREF1361_RS03040 HMPREF1361_RS03595 fructokinase: phosphoglucomutase: HMPREF1361_RS06540 HMPREF1361_RS03980 glucokinase: dienoyl-[acp] IMP a [prolipoprotein]-S- pyruvate kinase: HMPREF1361_RS13520 fructokinase: GMP [+ 2 isozymes] HMPREF1361_RS07640 Fatty Acid and Lipid Biosynthesis diacylglyceryl-L-cysteine HMPREF1361_RS09060 D-glucopyranose HMPREF1361_RS03980 XMP D-glucopyranose 1-palmitoyl- a 2'- 1915 2251 a (3R,6Z)-3- adenosine 6-phosphate L-arabinose degradation I [+ 2 isozymes] undecaprenyldiphospho- a pseudouridine guanosine a nucleoside a cation RS06080 a cation 6-phosphate N-acetylmuramoyl-L- sn-glycerol a myristoyl-[acp] deoxyribonucleoside [DNA] glycocholate hydroxyoctadec- 2',3'-cyclic palmitate biosynthesis II (bacteria and plants) signal peptidase II: pyruvate glucose-6- UDP-N-acetyl- inosine in 23S rRNA in 23S rRNA diphosphate palmitoleate biosynthesis I gondoate biosynthesis (anaerobic) alanyl-γ-D-glutamyl-meso 3-phosphate 5'-triphosphate 23S rRNA choloylglycine hydrolase: 23S rRNA 6-enoyl-[acp] monophosphate nucleoside- Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis HMPREF1361_RS06045 phosphate L-arabinopyranose glucose-6- α-D-glucosamine 1-acyl-sn-glycerol-3- inosine-uridine preferring DNA polymerase 3-hydroxyacyl-[acyl- multifunctional 2',3'- (from (5Z)-dodec-5-enoate) -2,6-diaminopimeloyl- (pseudouridine(1915)-N(3) HMPREF1361_RS13095 (guanosine(2251)-2'-O)- diphosphate kinase: isomerase: pgi L-arabinose isomerase: phosphate phosphate acyltransferase: nucleoside hydrolase: III subunit delta: carrier-protein] cyclic-nucleotide 2'- a cation RS00375 a cation an acetoacetyl-[acp] an (S-diacyl-sn- isomerase: D-alanyl-D-alanine undecaprenyldiphospho- HMPREF1361_RS04300 HMPREF1361_RS06310 )-methyltransferase RlmH: choloylglycine hydrolase: methyltransferase RlmB: dehydratase FabZ: HMPREF1361_RS12095 [2Fe-2S] iron-sulfur cluster biosynthesis a (5Z)-dodec- a malonyl-[acp] an oleoyl-[acp] a lipoprotein HMPREF1361_RS13785 1-palmitoyl- HMPREF1361_RS03350 phosphodiesterase/ N 10 -formyl-tetrahydrofolate biosynthesis lipoate biosynthesis glutathione-peroxide demethylmenaquinol-6 biosynthesis I glyceryl)-L-cysteinyl- F6P pgi muramoylpentapeptide beta-N- 3 HMPREF1361_RS07855 HMPREF1361_RS11435 HMPREF1361_RS08535 HMPREF1361_RS03665 UDP kinase: glutathione biosynthesis 5-enoyl-[acp] beta-ketoacyl-[acyl-carrier- signal peptide Fermentation L-ribulose acyl-carrier protein 2-myristoyl hypoxanthine D-ribofuranose [+ 7 isozymes] an N - 2-O- 5'-nucleotidase/ 3-oxoacyl-ACP reductase: beta-ketoacyl-[acyl-carrier- [apolipoprotein] acetylglucosaminyltransferase: 1915 2251 and incorporation II redox reactions phosphatidate [DNA] methylpseudouridine gly cholate methylguanosine 3-hydroxyacyl-[acyl- 3'-nucleotidase: HMPREF1361_RS00575 all-trans- HMPREF1361_RS07985 protein] synthase II: protein] synthase II: F6P lipid II (HMPREF1361_RS07030meso a nucleoside glycine glycine L-cysteine desulfurase 2-carboxy-1,4- an (11Z)-3- ribose phosphorylation UDP in 23S rRNA in 23S rRNA carrier-protein] HMPREF1361_RS10010 RS12865 a tetrahydrofolate octanoate GSSG hexaprenyl [+ 2 isozymes] a (7Z)-3- HMPREF1361_RS05585 HMPREF1361_RS05585 pyruvate fermentation diaminopimelate containing) triphosphate betaine betaine cys glu naphthoquinol oxo-icos-11- dehydratase FabZ: 3'-AMP diphosphate1,4-dihydroxy-2-naphthoate a (3R)-3- oxotetradec- to (R)-acetoin II chitobiose degradation cysteine desulfurase: bifunctional glutamate- lipoate--protein ligase A: an N-acyl-(S-diacyl- β HMPREF1361_RS05595 polyprenyltransferase: hydroxybutanoyl- 7-enoyl-[acp] enoyl-[acp] a peptide -D-ribopyranose a (2E,6Z)- HMPREF1361_RS04650 -cysteine ligase HMPREF1361_RS06845 3-oxoacyl-[acyl-carrier- sn-glyceryl)-L- L-ribulose 5-phosphate dihydrofolate reductase: a [lipoyl-carrier protein] HMPREF1361_RS13470 [acp] 3-oxoacyl-[acyl-carrier- pyruvate D-ribose pyranase: N,N'- octadecadienoyl- glycine glycine [+ 3 isozymes] GshA/glutathione glutathione- protein] reductase: cysteinyl-[lipoprotein] RS11185 N 6 -octanoyl-L-lysine demethylmenaquinol-6 3-hydroxyacyl-[acyl- protein] reductase: acetolactate synthase AlsS: HMPREF1361_RS10675 L-ribulose-5-phosphate diacetylchitobiose [acp] betaine betaine HMPREF1361_RS13930 synthetase GshB: disulfide reductase: an S-sulfanyl-[L- carrier-protein] HMPREF1361_RS05580 HMPREF1361_RS05580 HMPREF1361_RS11025 β-D-ribofuranose 4-epimerase: araD 6'-phosphate [+ 2 isozymes] HMPREF1361_RS02705 HMPREF1361_RS05075 cysteine desulfurase] γ-L-glutamyl- dehydratase FabZ: [+ 2 isozymes] (S)-2-acetolactate L-ribulose-5-phosphate [+ 2 isozymes] a (3R,11Z)-3- ditrans,octacis-undecaprenyldiphospho- 1-palmitoyl- 4-(cytidine 5'- a (3R,9Z)-3- guanosine L-cysteine HMPREF1361_RS03665 a (3R,7Z)-3- 4-epimerase AraD: araD N-monoacetylchitobiose a cis- coenzyme A NADP + a 3-oxohexacosanoyl- 3'-UMP glycine glycine a [lipoyl-carrier N 6 -L-threonylcarbamoyladenosine 37 N-acetyl-(N-acetyl-β-D-glucosaminyl) sn-glycerol 3'-dephospho- diphospho)-2-C- a malonyl-[acp] hydroxy-octadec- 2',3'-cyclic RS08100 hydroxytetradec- hydroxy-icos- acetolactate decarboxylase: 6'-phosphate D-aspartate vaccenoyl-[acp] ATP [acp] betaine betaine bifunctional glutamate- protein]-N 6 -[(R)- 3-hydroxyacyl-[acyl- 11-enoyl-[acp] -modified tRNA biosynthesis muramoyl-L-alanyl-γ-D-glutamyl- 3-phosphate1-acyl-sn-glycerol-3- CoA-disulfide reductase: CoA methyl-D-erythritol4-(cytidine 5'- 9-enoyl-[acp]3-hydroxyacyl-[acyl- monophosphate multifunctional 2',3'- glutathione demethylmenaquinol-9 biosynthesis 7-enoyl-[acp] HMPREF1361_RS11020 α D-xylulose 5-phosphate 6-phospho-beta- 3-oxoacyl-ACP reductase: beta-ketoacyl-[acyl-carrier- multifunctional 2',3'- -cysteine ligase dihydrolipoyl]-L-lysine carrier-protein] 3-hydroxyacyl-[acyl- -D-ribofuranose L-lysyl-D-alanyl-D-alanine D-aspartate ligase: phosphate acyltransferase: HMPREF1361_RS10945 dephospho-CoA kinase: diphospho)-2-C-methyl- carrier-protein] cyclic-nucleotide 2'- an S-sulfanyl-[cysteine serine lipoate salvage I 3-hydroxyacyl-[acyl- glucosidase: HMPREF1361_RS07985 protein] synthase II: cyclic-nucleotide 2'- a 7,8-dihydrofolate a 5-methyltetrahydrofolate GshA/glutathione all-trans- dehydratase FabZ: carrier-protein] HMPREF1361_RS05925 HMPREF1361_RS04300 CoA-disulfide reductase: HMPREF1361_RS01150 D-erythritol kinase: dehydratase FabZ: phosphodiesterase/ desulfurase]-[disordered- hydroxymethyltransferase: glyA 2-carboxy-1,4- carrier-protein] (R)-acetoin gellan degradation ribokinase: HMPREF1361_RS04935 ditrans,octacis-undecaprenyldiphospho- 1-palmitoyl-2- HMPREF1361_RS05585 phosphodiesterase/ synthetase GshB: nonaprenyl HMPREF1361_RS05595 ATP thr HMPREF1361_RS02090 [+ 2 isozymes] 5'-nucleotidase/ + F0F1 ATP + dehydratase FabZ: + HMPREF1361_RS08610 a 3- HMPREF1361_RS05595 H H form scaffold HMPREF1361_RS02705 (R)-lipoate naphthoquinol dehydratase FabZ: HMPREF1361_RS10670 [+ 3 isozymes] N-acetyl-(N-acetylglucosaminyl) acyl-carrier protein cis-vaccenoyl ADP coenzyme A H a (3R)-3- 2-phospho-4-(cytidine 5'-nucleotidase/ synthase diphosphate 1,4-dihydroxy-2-naphthoate HMPREF1361_RS05595 threonylcarbamoyl- H + NADPH CoA-disulfide 3'-nucleotidase: protein] complex a (2E)-but- HMPREF1361_RS05595 α N-acetyl-D- muramoyl-L-alanyl-γ-D-glutamyl-N-(β- phosphatidate hydroxyhexacosanoyl- 5'-diphospho)-2-C- oxodocosanoyl- 3-hydroxyacyl-[acyl- 3'-nucleotidase: [cysteine desulfurase]-S- lipoate--protein ligase A: polyprenyltransferase: AMP synthase: gellan -D-ribose trehalose degradation I (low osmolarity) HMPREF1361_RS10010 glutathione 2-enoyl-[acp] 3-hydroxyacyl-[acyl- glucosamine D-glucosamine D-asparatyl)-L-lysyl-D-alanyl-D-alanine [acp] methyl-D-erythritol [acp] carrier-protein] HMPREF1361_RS10010 sulfanylcysteine:[acceptor HMPREF1361_RS06845 HMPREF1361_RS13470 3-hydroxyacyl-[acyl- (L-threonylcarbamoyl)HMPREF1361_RS10365 5-phosphate uridine bifunctional a (6S)-5- demethylmenaquinol-9 crotonyl-[acyl-carrier- carrier-protein] carrier-protein] α,α-trehalose 6-phosphate dehydratase FabZ: 3'-GMP V-type ATP protein]-cysteine (lipoyl)adenylate adenylate + + thymidylate synthase: methylenetetrahydrofolate formyltetrahydrofolate protein] reductase: dehydratase FabZ: dehydratase FabZ: unsaturated gellan 6-phosphate a (2E,9Z)- HMPREF1361_RS03665 H synthase H sulfurtransferase: 6 HMPREF1361_RS13430 dehydrogenase/ 5-formyltetrahydrofolate lipoate--protein ligase A: HMPREF1361_RS03670 HMPREF1361_RS03665 HMPREF1361_RS03665 N -L- tetrasaccharide octadeca-2,9- HMPREF1361_RS04650 threonylcarbamoyladenine a [cysteine desulfurase]- thymidylate synthase: methenyltetrahydrofolate cyclo-ligase: HMPREF1361_RS06845 a (2E,7Z)- a (2E,11Z)-icosa- glycosyl hydrolase alpha,alpha- dienoyl-[acp] a butanoyl-[acp] synthase: S-sulfanyl-[disordered- HMPREF1361_RS12675 cyclohydrolase: HMPREF1361_RS07625 thiamine salvage III a [lipoyl-carrier tetradeca-2,7- 2,11-dienoyl-[acp] family 88: phosphotrehalase: xylose degradation I Co 2+ RS01720 Co 2+ thiamine RS08645 thiamine HMPREF1361_RS06950 6 acyl carrier protein activation HMPREF1361_RS07695 HMPREF1361_RS02060 form scaffold a 5,10- a 5,10- protein]-N - dienoyl-[acp] 6 HMPREF1361_RS10645 (2E,11Z)-icosa-2,11- an N -L- 2503 1-cis-vaccenoyl- a (7Z)-3- beta-ketoacyl-[acyl-carrier- cis-∆ 7 -tetradecenoyl- 4-deoxy-L- β-D-Glcp-(1->4) adenine salicin 6- a ribonucleoside 3'-cmp protein] complex methylenetetrahydrofolate methenyltetrahydrofolate lipoyl-L-lysine 37 D-xylopyranose a cis- a 3-oxotetracosanoyl- NMN cysteine desulfurase: thiamine protein] synthase II: [acp]:NAD+ dienoyl-[acp] reductase: threonylcarbamoyladenine threo-hex-4- -α-L-Rhap- in 23S rRNA sn-glycerol- a tRNA precursor CTP ATP phosphate ATP H O oxohexacos- 5'-monophosphate an apo acyl- Respiration 23S rRNA vaccenoyl-[acp] 6-phospho-beta- 2 [acp] multifunctional 2',3'- HMPREF1361_RS04650 bifunctional thiamine diphosphokinase: coenzyme A HMPREF1361_RS05585 oxidoreductase: HMPREF1361_RS03670 in tRNA enopyranuronate (1->3)-D-Glcp glucokinase: 3-phosphate1-acyl-sn-glycerol-3- 7-enoyl-[acp] multifunctional 2',3'- multifunctional 2',3'- folate RS10180 folate a purine RS06535 a purine carrier protein (adenine(2503)-C(2))- CCA tRNA glucosidase: ATPase P: 3-oxoacyl-ACP reductase: 3-oxoacyl-ACP reductase: cyclic-nucleotide 2'- [+ 3 isozymes] methylenetetrahydrofolate HMPREF1361_RS08725 holo-ACP synthase: 3-oxoacyl-[acyl-carrier- HMPREF1361_RS03670 D-glucopyranose HMPREF1361_RS07640 phosphate acyltransferase: cyclic-nucleotide 2'- cyclic-nucleotide 2'- an S-sulfanyl-[cysteine dehydrogenase/ thiamine HMPREF1361_RS01320 a gondoyl-[acp] 2-oxoglutarate decarboxylation to succinyl-CoA D-glucopyranose D-xylulose methyltransferase RlmN: nucleotidyltransferase: HMPREF1361_RS04935 HMPREF1361_RS13895 HMPREF1361_RS07985 HMPREF1361_RS07985 phosphodiesterase/ phosphodiesterase/ a holo acyl- protein] reductase: fructose degradation 6-phosphate HMPREF1361_RS043001,2-dicis- phosphodiesterase/ desulfurase]-S- methenyltetrahydrofolate diphosphate folate polyglutamylation 3',5'-ADP a (7Z)-tetradec- HMPREF1361_RS10285 a tRNA HMPREF1361_RS12650 [+ 3 isozymes] [+ 4 isozymes] [+ 2 isozymes] [+ 2 isozymes] 5'-nucleotidase/ 5'-nucleotidase/ carrier protein HMPREF1361_RS05580 xylulose kinase: acyl-carrier protein vaccenoyl- a (3R)-3- a (3R,7Z)-3- 5'-nucleotidase/ lipoate salvage II 7-enoyl-[acp] a [2-oxoglutarate β a 2-methyladenine 2503 containing a β-D-glucose H + phosphate ADP 3'-nucleotidase: folate RS12720 folate L-cystine RS01090 L-cystine sulfanyl-[disordered- hydroxymethylpyrimidine cyclohydrolase: -D-fructofuranose HMPREF1361_RS08390 5'-deoxyadenosine met phosphatidate salicyl alcohol hydroxytetracosanoyl- hydroxyhexacos- 3'-nucleotidase: 3'-nucleotidase: a 3-oxohexanoyl- dehydrogenase in 23S rRNA 3' CCA end 6-phosphate HMPREF1361_RS10010 form scaffold salvage a [lipoyl-carrier HMPREF1361_RS06950 a tetrahydrofolate beta-ketoacyl-[acyl-carrier- 1-phosphate [acp] 7-enoyl-[acp] HMPREF1361_RS10010 HMPREF1361_RS10010 [acp] E2 protein] N 6 1-phosphofructokinase: D-xylulose 1-(β-D protein] complex 6 an N 10 - protein] synthase II: D-mannose degradation cytidine [cysteine desulfurase]-S- 4-amino-2-methyl-5- protein]-N - -lipoyl-L-lysine dihydrolipoamide HMPREF1361_RS11715 5-phosphate a ribonucleoside ribofuranosyl) formyltetrahydrofolate 3-oxoacyl-ACP reductase: HMPREF1361_RS05585 biotin-carboxyl carrier protein assembly Mg 2+ RS09770 Mg 2+ chloride RS09410 chloride sulfanylcysteine:[acceptor pyrimidinemethanol lipoyl-L-lysine formate-- bifunctional serine dihydrolipoamide dehydrogenase: 1-phosphofructokinase: nicotinamide bifunctional HMPREF1361_RS07985 3-oxoacyl-[acyl-carrier- D-mannopyranose melibiose degradation protein]-cysteine tetrahydrofolate ligase: folylpolyglutamate synthase/ hydroxymethyltransferase: glyA dehydrogenase: HMPREF1361_RS04640 HMPREF1361_RS00900 hydroxymethylpyrimidine [+ 2 isozymes] protein] reductase: a [biotin carboxyl- β-D-fructose 1,6- 6-phosphate sulfurtransferase: (R)-lipoate HMPREF1361_RS06060 dihydrofolate synthase: HMPREF1361_RS04640 mannose-6-phosphate UDP-N-acetyl-α-D-muramoyl- 1-palmitoyl- (R)-4'- a 3,5,7,9,11,13,15- a (5Z)-3- kinase/ a (3R)-3- carrier protein]-L-lysine bisphosphate arbutin-6- 1-(18-hydroxyoleoyl)- a ribonucleoside 2+ 2+ HMPREF1361_RS04650 HMPREF1361_RS05580 isomerase, class I: melibiose γ a cytosine in DNA acetyl-CoA Co Co 2+ 2+ a [cysteine HMPREF1361_RS07290 a 5,10- dihydrolipoyl L-alanyl- -D-glutamyl- D-alanyl-D-alanine a palmitoyl-[acp] sn-glycerol phosphopantothenoyl- hepta-oxo- oxotetracos- Ca RS13245 Ca phosphomethylpyrimidine hydroxyhexanoyl- a (9Z)-3- phosphate sn-glycrol 3-phosphate 3'-phosphate 2+ 2+ 10 biotin--[acetyl-CoA- alpha-galactosidase: Ni RS07580 Ni desulfurase]-(S- kinase: lipoate--protein ligase A: an N - methylenetetrahydrofolate dehydrogenase: HMPREF1361_RS10480 meso-2,6-diaminopimelate 3-phosphate L-cysteine 6-phospho-beta- hexadecanoyl-[PKS-acp] 5-enoyl-[acp] DNA (cytosine-5-)- acetyl-CoA carboxylase [acp] oxohexadec- carboxylase] ligase: HMPREF1361_RS00970 UDP-N-acetylmuramoyl- 1-acyl-sn-glycerol-3- 1-acyl-sn-glycerol-3- multifunctional 2',3'- 2+ 2+ sulfanyl) -[disordered- HMPREF1361_RS06845 formyltetrahydrofolate bifunctional HMPREF1361_RS06405a [2-oxoglutarate a [2-oxoglutarate F6P phosphopantothenoylcysteine glucosidase: aldo/keto reductase: 3-oxoacyl-ACP reductase: methyltransferase: biotin carboxyl Mg Mg 2 HMPREF1361_RS12425 a tetrahydrofolate 3-hydroxyacyl-[acyl- 9-enoyl-[acp] HMPREF1361_RS08780 tripeptide--D-alanyl- phosphate acyltransferase: phosphate acyltransferase: cyclic-nucleotide 2'- form scaffold dehydrogenase dehydrogenase D-galactopyranose D-glucopyranose decarboxylase: HMPREF1361_RS04935 HMPREF1361_RS06465 HMPREF1361_RS07985 HMPREF1361_RS04830 carrier protein: bifunctional folylpolyglutamate synthase/ carrier-protein] 3-oxoacyl-ACP reductase: D- alanine ligase: HMPREF1361_RS04300 HMPREF1361_RS04300 phosphodiesterase/ arg arg hydroxymethylpyrimidine/ (lipoyl)adenylate a [biotin carboxyl-carrier E2 protein] N 6 E2 protein] N 6 -S- HMPREF1361_RS02875 [+ 2 isozymes] [+ 2 isozymes] protein] complex folylpolyglutamate synthase/ dihydrofolate synthase: dehydratase FabZ: HMPREF1361_RS07985 dipalmitoyl [+ 3 isozymes] 1-[18-hydroxyoeoyl]-2- DNA (cytosine-5-)- HMPREF1361_RS05590 + + phosphomethylpyrimidine 6 UDP-N-acetyl-α-D-muramoyl-L-HMPREF1361_RS01330 acyl-carrier protein β 9-hydroxy-3,5,7,11,13,15- a (3R,5Z)-3- 5'-nucleotidase/ Na RS03205 Na RS04675 HMPREF1361_RS07290 protein]-N -biotinyl-L-lysine -dihydrolipoyl- succinyldihydrolipoyl- phosphatidate 4'-phosphopantetheine -D-glucose kinase: lipoate--protein ligase A: dihydrofolate synthase: HMPREF1361_RS03665 [+ 2 isozymes] alanyl-γ-D-glutamyl-meso-2,6- hydroquinone [18-hydroxy-lioleoyl]-sn hexaoxohexadecanoyl- hydroxytetracos- methyltransferase: 3'-nucleotidase: [+ 3 isozymes] ornithine ornithine a (3R,9Z)-3- L-lysine L-lysine 6-phosphate HMPREF1361_RS00175 HMPREF1361_RS06845 HMPREF1361_RS07290 a 5,10- 3-hydroxyacyl-[acyl- diaminopimeloyl-D-alanyl-D-alanine -glycerol 3-phosphate [PKS-acp] 5-enoyl-[acp] HMPREF1361_RS08290 HMPREF1361_RS10010 malonyl-CoA citrate RS08755 citrate 10 hydroxyhexadec- a 5-methylcytosine a [cysteine desulfurase]- HMP-P an N - methylenetetrahydrofolate carrier-protein] a ribonucleoside a [glycine- 9-enoyl-[acp] a [biotin carboxyl- in DNA Na + RS03170 Na + [scaffold protein- formyltetrahydrofolate dehydratase FabZ: Detoxification cleavage complex 3-hydroxyacyl-[acyl- carrier-protein dimer]- (2Fe-2S)] complex bifunctional H protein] N 6 - HMPREF1361_RS05595 dihydrolipoamide carrier-protein] N 6 -biotinyl-L-lysine 2+ 2+ hydroxymethylpyrimidine heptaprenyl diphosphate dehydrogenase: DNA with adenine:7,8- cytidine 2',3'-cyclic Cu RS02625 Cu lipoyl-L-lysine a (2E)-hex- dehydratase FabZ: reactive oxygen species degradation arsenate detoxification decaprenyl-diphospho-N- UDP-N-acetyl- a [protein] N-terminal- an (11Z)-3- (3R,5S)-3- kinase/ tetrahydrofolate biosynthesis biosynthesis acetyl-CoA HMPREF1361_RS04640 Nucleoside and Nucleotide Degradation α a (3Z)-dec- maltohexaose dihydro-8- a 3-oxooctadecanoyl- monophosphate DNA with lesion 2-enoyl-[acp] HMPREF1361_RS05595 acetyl-CoA carboxylase II (glutaredoxin) acetylmuramoyl-pentapeptide -D-glucosamine a malonyl-[acp] formyl-L-methionine oxooctadec- hydroxy-1- sulfate RS04715 sulfate phosphomethylpyrimidine carboxylase carboxyl: undecaprenyldiphospho- 3-enoyl-[acp] alpha-glucosidase: peptide deformylase: oxoguanine mismatch [acp] multifunctional 2',3'- excinuclease ABC: a [co-chaperone]- (7,8-dihydropterin- di-trans,poly-cis-undecaprenyl menaquinol-7 biosynthesis (2E,6E)-farnesyl biotin carboxylase subunit: beta-ketoacyl-[acyl-carrier- A/G-specific adenine 11-enoyl-[acp] pyrroline-5- kinase: IPP hexanoyl-[acyl-carrier- 3-hydroxyacyl-[acyl- HMPREF1361_RS05605 purine nucleotides degradation II (aerobic) superoxide muramoylpentapeptide beta-N- HMPREF1361_RS08215 HMPREF1361_RS11930 3-oxoacyl-ACP reductase: 3-oxoacyl-ACP reductase: cyclic-nucleotide 2'- HMPREF1361_RS05915 carboxylate [scaffold protein- a [lipoyl-carrier 4-aminobenzoate 6-yl)methyl phosphate biosynthesis diphosphate HMPREF1361_RS05600 superpathway of pyrimidine arsenate protein] synthase II: glycosylase: pyrroline-5- nitrate RS12885 nitrate HMPREF1361_RS12425 heptaprenyl diphosphate protein] reductase: carrier-protein] HMPREF1361_RS05610 acetylglucosaminyltransferase: alpha-glucosidase: peptide deformylase: HMPREF1361_RS07985 HMPREF1361_RS07985 phosphodiesterase/ HMPREF1361_RS05920 (2Fe-2S)] complex protein]-N 6 - diphosphate all-trans-heptaprenyl a [carboxyl-carrier ribonucleosides degradation arsenate reductase: HMPREF1361_RS05585a (5Z)-3- HMPREF1361_RS05480 carboxylate reductase: sulfate RS10755 sulfate (2E,6E)-farnesyl synthase subunit I: HMPREF1361_RS03670 dehydratase FabZ: Pentose Phosphate Pathways superoxide dismutase: HMPREF1361_RS07030 HMPREF1361_RS00190 HMPREF1361_RS08690 [+ 2 isozymes] [+ 2 isozymes] 5'-nucleotidase/ hydroxymethylpyrimidine/ diphosphate 6 an apurinic site excinuclease ABC lipoyl-L-lysine 7,8- IPP 1,4-dihydroxy-2-naphthoate HMPREF1361_RS13445 HMPREF1361_RS03665 protein dimer]-N - HMPREF1361_RS00385 HMPREF1361_RS04735 decaprenyl-pyrophosphoryl- acyl-carrier protein oxododec- an N-terminal L- adenine a (3R)-3- a (3R,11Z)-3- 3'-nucleotidase: HMPREF1361_RS08600 phosphomethylpyrimidine dihydropteroate diphosphatedi-trans,poly-cis-decaprenyl all-trans-heptaprenyl AMP cytidine UDP (N-acetylglucosamine)-N- 5-enoyl-[acp] D-glucopyranose maltopentaose formate within DNA hydroxyoctadecanoyl- hydroxyoctadec- subunit UvrC: polyprenyltransferase: a hexanoyl-[acp] a (2E,9Z)- carboxybiotinyl-L-lysine pentose phosphate pathway (non-oxidative branch) cytidine deaminase: hydrogen arsenate reductase: methionyl-[protein] HMPREF1361_RS10010 Hyp predicted kinase: diphosphate:isopentenyl- diphosphate acetylmuramyl-(pentapeptide) [acp] 11-enoyl-[acp] HMPREF1361_RS03165 a [chaperone-ATP]- bifunctional HMPREF1361_RS13470 hexadeca-2,9- HMPREF1361_RS10590 2+ 2+ ABC HMPREF1361_RS00175 multifunctional 2',3'- HMPREF1361_RS02385 peroxide 3'-cmp DNA without Zn RS08615 Zn [co-chaperone]- folylpolyglutamate synthase/ diphosphate demethylmenaquinol-7 3-oxoacyl-[acyl-carrier- dienoyl-[acp] arsenite met transporter met D-ribulose cyclic-nucleotide 2'- uridine lesion [scaffold protein- dihydrofolate synthase: undecaprenylcistransferase: protein] reductase: palmitoleoyl-[acp]:NAD+ of L- HMP-PP thioredoxin pathway 5-phosphate phosphodiesterase/ pyrimidine-nucleoside catalase: (2Fe-2S)] complex HMPREF1361_RS07290 di-trans,octa-cisHMPREF1361_RS05760 HMPREF1361_RS05580 oxidoreductase: Electron Transfer IMP methionine 5'-nucleotidase/ phosphorylase: deoA HMPREF1361_RS04160 -undecaprenyl HMPREF1361_RS03670 RNase III mRNA a β-D- a (6Z)-3- uridine 2'3'-cyclic a [protein]- Zn 2+ RS01670 Zn 2+ 7,8-dihydrofolate beta-ketoacyl-[acyl-carrier- ribose-5-phosphate ribulose-phosphate GMP a (7Z)-hexadec- a uracil in DNA 1-myristoyl-sn- NaMN an oxidized diphosphate 3'-nucleotidase: uracil H O hydroxyl radical processing substrate a malonyl-[acp] fructofuranoside acyl-carrier protein oxooctadec- monophosphate L-tyrosine met RS12080 met monoglutamate protein] synthase II: isomerase RpiA: 3-epimerase: ATP biosynthesis IMP dehydrogenase: 2 glycerol 3-phosphate thioredoxin undecaprenyl- menaquinol-7 a palmitoleoyl-[acp] HMPREF1361_RS10010 O arsenite ribonuclease III: 7-enoyl-[acp] beta-fructofuranosidase: uracil-DNA glycosylase: 6-enoyl-[acp] multifunctional 2',3'- multifunctional 2',3'- tyrosine protein kinase: HMPREF1361_RS05585 HMPREF1361_RS02435 HMPREF1361_RS08720 HMPREF1361_RS09010 2 beta-ketoacyl-[acyl-carrier- 1-acyl-sn-glycerol-3- diphosphate phosphatase: multifunctional 2',3'- HMPREF1361_RS02685 HMPREF1361_RS10535 HMPREF1361_RS00850 3-oxoacyl-ACP reductase: cyclic-nucleotide 2'- cyclic-nucleotide 2'- HMPREF1361_RS00610 a [chaperone- protein] synthase II: phosphate acyltransferase: ACP S-malonyltransferase: 2+ 2+ an [2Fe-2S] geranylgeranyl a 3-oxooctanoyl- adenosine cyclic-nucleotide 2'- beta-fructofuranosidase: HMPREF1361_RS07985 phosphodiesterase/ Zn RS10635 Zn ADP]-[disordered- HMPREF1361_RS06285 demethylmenaquinol-8 biosynthesis I acyl-ACP thioesterase: D-ribose 5- D-xylulose ribonuclease III: HMPREF1361_RS05585a (9Z)-3-oxo- uracil-DNA glycosylase: HMPREF1361_RS04300 HMPREF1361_RS13270 phosphodiesterase/ tyrosine protein kinase: glycine betaine glycine betainecluster protein diphosphate biosynthesis [acp] ADP phosphodiesterase/ HMPREF1361_RS10580 [+ 2 isozymes] 5'-nucleotidase/ RS11190 form scaffold thioredoxin- di-trans,octa-cis- HMPREF1361_RS07240 phosphate 5-phosphate XMP 5,6-dihydrouracil HMPREF1361_RS08530 acyl-carrier protein octadec-9- HMPREF1361_RS06880 1-myristoyl-2- a (3R,6Z)-3- 5'-nucleotidase/ a [protein]- HMPREF1361_RS00615 pro pro a 7,8-dihydrofolate V-type ATP synthase: 5'-nucleotidase/ RNase III processing β an apyrimidinic 3'-nucleotidase: protein] complex disulfide reductase: undecaprenyl phosphate (2E,6E)-farnesyl all-trans- 3-oxoacyl-ACP reductase: adenosine deaminase: an mRNA fragment enoyl-[acp] a glycoside -D-fructofuranose uracil palmitoleoyl-sn- a malonyl-[acp] hydroxyoctadec- 3'-nucleotidase: L-tyrosine 2-carboxy-1,4- palmitoleate HMPREF1361_RS03195 3'-nucleotidase: product mRNA site in DNA HMPREF1361_RS10010 HMPREF1361_RS04415 dihydrofolate reductase: diphosphate octaprenyl HMPREF1361_RS07985 transketolase: HMPREF1361_RS05870 multifunctional 2',3'- hydantoinase: glycerol 3-phosphate 6-enoyl-[acp] HMPREF1361_RS10010 phosphate sulfite RS08745 sulfite geranylgeranyl naphthoquinol HMPREF1361_RS03200 HMPREF1361_RS10010 β-D- HMPREF1361_RS13930 diphosphate1,4-dihydroxy-2-naphthoate [+ 2 isozymes] HMPREF1361_RS05070 cyclic-nucleotide 2'- HMPREF1361_RS07925 3'-UMP pyrophosphate synthase: polyprenyltransferase: a (3R)-3- HMPREF1361_RS03210 phosphodiesterase/ ribosylnicotinate an [Fe-S cluster a [disordered- [+ 2 isozymes] a reduced HMPREF1361_RS13440 HMPREF1361_RS13470 hydroxyoctanoyl- phosphatidylglycerol D-sedoheptulose D-glyceraldehyde HMPREF1361_RS03215 inosine guanosine 5'-nucleotidase/ 3-ureidopropanoate biosynthesis form [Fe-S] cluster thioredoxin a tetrahydrofolate GGPP demethylmenaquinol-8 [acp] biosynthesis I (plastidic) 7-phosphate 3-phosphate HMPREF1361_RS03220 3'-nucleotidase: Aldehyde Degradation gln RS11900 gln chaperone]-ATP scaffold protein] phosphatidylglycerophosphate a (1->4)- 1-cis-vaccenoyl-sn- a 3- a negatively 3-hydroxyacyl-[acyl- HMPREF1361_RS03225 purine-nucleoside purine-nucleoside HMPREF1361_RS10010 a (5Z)-tetradec- maltopentaose α a cis-delta13-3- a kanamycin (1-octadecenoyl(9Z), 2-palmitoyl) a malonyl-[acp] -D-glucan glycerol-3-phosphate oxodocosanoyl- supercoiled DNA asp carrier-protein] DHAP transaldolase: HMPREF1361_RS03230 phosphorylase: phosphorylase: 5-enoyl-[acp] alpha-glucosidase: alpha-glucosidase: oxo-C32:1-[acp] DNA topoisomerase III: aminoglycoside methylglyoxal degradation I beta-ketoacyl-[acyl-carrier- 1-acyl-sn-glycerol-3- [acp] dehydratase FabZ: NAD(P)H-dependent HMPREF1361_RS09955 F0F1 ATP synthase: HMPREF1361_RS02420 HMPREF1361_RS02420 xanthosine L-lactaldehyde phosphatidylglycerophosphatase HMPREF1361_RS08215 HMPREF1361_RS08215 3-oxoacyl-ACP reductase: 3-oxoacyl-ACP reductase: HMPREF1361_RS04700 phosphotransferase: serine RS02005 serine β protein] synthase II: phosphate acyltransferase: aspartate racemase: HMPREF1361_RS03665 glycerol-3-phosphate purine-nucleoside purine-nucleoside -alanine degradation (anaerobic) A: HMPREF1361_RS09990 alpha-glucosidase: alpha-glucosidase: HMPREF1361_RS07985 HMPREF1361_RS07985 HMPREF1361_RS04150 thr thr HMPREF1361_RS03385 methylglyoxal aHMPREF1361_RS05585 (7Z)-3-oxo- HMPREF1361_RS04300 type IA DNA HMPREF1361_RS05930 3-hydroxyacyl-[acyl- dehydrogenase: D-erythrose phosphorylase: phosphorylase: HMPREF1361_RS00190 HMPREF1361_RS00190 [+ 2 isozymes] [+ 2 isozymes] aminoglycoside Cell Structure Biosynthesis F6P HMPREF1361_RS03390 lactoylglutathione lyase: 1-oleoyl-2-palmitoyl- acyl-carrier protein hexadec-7- 1-cis-vaccenoyl- a (3R)-3- a cis-delta13-3- topoisomerase: carrier-protein] HMPREF1361_RS03600 4-phosphate HMPREF1361_RS02415 HMPREF1361_RS02415 (S)-lactaldehyde a (1->4)- phosphotransferase: HMPREF1361_RS03395 purine-nucleoside HMPREF1361_RS03255 phosphatidylglycerol enoyl-[acp] D-glucopyranose maltotetraose D-glucopyranose α 2-palmitoleoyl-sn- hydroxydocosanoyl- hydroxyC32:1- HMPREF1361_RS00040 D-aspartate dehydratase FabZ: lactaldehyde reductase: -D-glucan HMPREF1361_RS07235 serine serine β NAD(P)H-dependent transketolase: HMPREF1361_RS03400 phosphorylase: glycerol-3-phosphate [acp] [acp] a relaxed DNA RS02000 peptidoglycan biosynthesis V ( -lactam resistance) HMPREF1361_RS05595 (R)-S- [+ 2 isozymes] HMPREF1361_RS08010 a kanamycin thr thr peptidoglycan biosynthesis IV (Enterococcus faecium) glycerol-3-phosphate HMPREF1361_RS05070 HMPREF1361_RS03405 hypoxanthine guanine HMPREF1361_RS02415 (S)-propane- Aminoacyl-tRNA Charging lactoylglutathione 3'-phosphate UDP-N-acetyl- a (2E)-oct- dehydrogenase: D-glyceraldehyde HMPREF1361_RS03410 purine-nucleoside 1,2-diol UDP-N-acetyl- α-D-glucosamine 2-enoyl-[acp] HMPREF1361_RS10125 3-phosphate HMPREF1361_RS03415 phosphorylase: serine serine tRNA charging α-D-glucosamine sn-glycerol RS03630 glutaminyl-tRNA gln UDP-N-acetylglucosamine HMPREF1361_RS03420 HMPREF1361_RS02420 a [formate C a 3- a (7Z)-3-oxo- a (5Z)-3- octanoyl-[acyl-carrier- 3-phosphate a reduced a (3Z)-dodec- maltoheptaose a peptide with a 1-palmitoyl-sn- a cis-delta21-3- thr thr biosynthesis via 1-carboxyvinyltransferase: UDP-N-acetylglucosamine ATP SAM acetyltransferase]- a malonyl-[acp] oxodocosanoyl- hexadec-7- oxododec- a protein 1-carboxyvinyltransferase: protein] reductase: glycerol-3-phosphate 1- (R)-lactate flavodoxin 3-enoyl-[acp] alpha-glucosidase: leader sequence glycerol 3-phosphate oxo-C40:1-[acp] arg transamidation HMPREF1361_RS03430 glycine pyruvate formate lyase- beta-ketoacyl-[acyl-carrier- signal peptidase I: [acp] enoyl-[acp]3-oxoacyl-[acyl-carrier- 5-enoyl-[acp]3-oxoacyl-[acyl-carrier- arginine--tRNA ligase: HMPREF1361_RS03430 HMPREF1361_RS03670 O-acyltransferase PlsY: xanthine HMPREF1361_RS08215 1-acyl-sn-glycerol-3- 3-oxoacyl-ACP reductase: 3-oxoacyl-ACP reductase: UDP-N-acetylglucosamine activating protein: protein] synthase II: HMPREF1361_RS12715 protein] reductase: protein] reductase: Clp protease ClpP: nitrite nitrite HMPREF1361_RS05715 glu HMPREF1361_RS12780 phosphate acyltransferase: HMPREF1361_RS07985 HMPREF1361_RS07985 RS02970 an L-arginyl- 1-carboxyvinyltransferase: UDP-N-acetylglucosamine an octanoyl-[acp] superpathway of purine deoxyribonucleosides degradation HMPREF1361_RS12805 HMPREF1361_RS05585 alpha-glucosidase: [+ 3 isozymes] HMPREF1361_RS05580 HMPREF1361_RS05580 HMPREF1361_RS13400 formate formate Arg a 1-acyl-sn a [formate C a (5Z)-3-oxo- HMPREF1361_RS04300 [+ 2 isozymes] [+ 2 isozymes] [tRNA ] HMPREF1361_RS01255 1-carboxyvinyltransferase: a flavodoxin HMPREF1361_RS00190 1-palmitoyl-2- Arg -glycerol 3- met 5'-deoxyadenosine acetyltransferase]- acyl-carrier protein tetradec-5- a leader sequence a peptide a (3R)-3- a cis-delta21-3- a (3R,7Z)-3-[+ 2 isozymes] a (3R,5Z)-3-[+ 2 isozymes] a tRNA HMPREF1361_RS01255 3-oxoacyl-[acyl-carrier- semiquinone UDP-N-acetyl-α- phosphate pyruvate glycin -2-yl radical enoyl-[acp] D-glucopyranose maltohexaose palmitoleoyl-sn- hydroxydocosanoyl- hydroxyC40:1- hydroxy-hexadec- hydroxydodec- a peptide an L-glutamyl- UDP-N-acetyl-α- protein] reductase: 2'-deoxyguanosine glycerol 3-phosphate 4-aminobutanoate 4-aminobutanoate Gln D-glucosamine- 1-acyl-sn-glycerol-3- urate [acp] [acp] 7-enoyl-[acp] 5-enoyl-[acp] [tRNA ] HMPREF1361_RS05580 enolpyruvate D-glucosamine- phosphate acyltransferase: 2'-deoxyadenosine RS09695 glutamyl-tRNA(Gln) UDP-N- enolpyruvate beta-ketoacyl-[acyl-carrier- HMPREF1361_RS04300 glutamate glutamate amidotransferase: a 1,2-diacyl- a guanine 34 a (3R,5Z)-3- a [protein]-L- cys acetylenolpyruvoylglucosamine UDP-N- protein] synthase II: purine-nucleoside 1-stearoyl-sn- a cis- sn-glycerol a [ThiI sulfur-carrier queuine a 3-oxoglutaryl- a cis-delta19-3- predicted cysteine--tRNA ligase: HMPREF1361_RS09525 acetylenolpyruvoylglucosamine HMPREF1361_RS05585 sn-glycerol a palmitoyl-[acp] cys 4'-phosphopantetheine ATP in tRNA hydroxy-tetradec- methionine tyr reductase: adenosine deaminase: phosphorylase: glycerol 3-phosphate vaccenoyl-[acp] 3-phosphate protein]-L-cysteine tRNA guanosine(34) [acp] methyl ester oxo-C38:1-[acp] peptide-methionine D-mannitol PEP-driven HMPREF1361_RS08525 an L-cysteinyl- reductase: 3-phosphate 1-acyl-sn-glycerol-3- glycerol-3-phosphate 1- cysteine desulfurase: 5-enoyl-[acp]3-oxoacyl-[acyl-carrier- tyrosine decarboxylase: D-mannitol Asp-tRNA(Asn) HMPREF1361_RS05210 a 3-oxodecanoyl- HMPREF1361_RS05870 HMPREF1361_RS02420 pantetheine-phosphate transglycosylase Tgt: 3-oxoacyl-ACP reductase: 3-oxoacyl-ACP reductase: (S)-S-oxide reductase: 1-phosphate transporter Cys HMPREF1361_RS05210 phosphatidate phosphate acyltransferase: O-acyltransferase PlsY: HMPREF1361_RS07270 protein] reductase: [tRNA ] /Glu-tRNA(Gln) ala UDP-N-acetyl- [acp] purine-nucleoside HMPREF1361_RS07985 HMPREF1361_RS07985 HMPREF1361_RS13140 HMPREF1361_RS13230 of D-mannitol a tRNA Cys ala cytidylyltransferase: HMPREF1361_RS04300 HMPREF1361_RS12780 [+ 3 isozymes] adenylyltransferase: HMPREF1361_RS08080 HMPREF1361_RS05580 amidotransferase: α-D-muramate glu UDP-N-acetyl- phosphorylase: 1-cis-vaccenoyl- a [ThiI sulfur- [+ 2 isozymes] [+ 2 isozymes] tyrosine decarboxylase: α 3-oxoacyl-ACP reductase: HMPREF1361_RS05765 purine-nucleoside 1-stearoyl-2-palmitoyl- HMPREF1361_RS06345 34 [+ 3 isozymes] HMPREF1361_RS00925 -D-muramate glu acyl-carrier protein acyl-carrier protein sn-glycerol- carrier protein]-S- ala 3'-dephospho- a queuosine a (3R)-3- a cis-delta19-3- a (5Z)-3-oxo-[+ 2 isozymes] a protein-L- HMPREF1361_RS10865 predicted HMPREF1361_RS07985 phosphorylase: 2'-deoxyinosine HMPREF1361_RS02415 sn-glycerol 3-phosphate guanine gatA UDP-N-acetylmuramate- a CDP- 3-phosphate sulfanyl-L-cysteine CoA in tRNA hydroxyglutaryl- hydroxyC38:1- tetradec-5- methionine- tyramine ABC glutamate racemase: UDP-N-acetylmuramate- [+ 2 isozymes] HMPREF1361_RS02420 phosphate phosphate HMPREF1361_RS00935 -L-alanine ligase: glutamate racemase: diacylglycerol [acp] methyl ester [acp] enoyl-[acp] (S)-S-oxide transporter HMPREF1361_RS03700 -L-alanine ligase: a (3R)-3- purine-nucleoside HMPREF1361_RS01125 HMPREF1361_RS03700 CDP-diacylglycerol-- purine-nucleoside of phosphate gln an L-glutaminyl- HMPREF1361_RS01125 hydroxydecanoyl- phosphorylase: Gln glycerol-3-phosphate 3- phosphorylase: superpathway of pyrimidine a 1-alkyl-sn [tRNA ] UDP-N-acetyl-α-D- D-glt [acp] HMPREF1361_RS02415 N-succinyl- a [protein]- a (9Z)-3-oxo- sn-glycerol an L-glutaminyl- α D-glt phosphatidyltransferase: HMPREF1361_RS02420 deoxyribonucleosides degradation 1-stearoyl-sn- isobutanoate a sulfurated FAD -glycerol 3- a cis-delta11-3- muramoyl-L-alanine UDP-N-acetyl- -D- 3-hydroxyacyl-[acyl- a stearoyl-[acp] hydrogen cyanide L,L-2,6- L-threonine octadec-9- 3-phosphate Gln HMPREF1361_RS08580 glycerol 3-phosphate [sulfur carrier] oxo-C30:1-[acp] GTP H O [tRNA ] muramoyl-L-alanine carrier-protein] purine-nucleoside acetate--CoA ligase: diaminopimelate FAD:protein FMN phosphate enoyl-[acp]3-oxoacyl-[acyl-carrier- 2 Gln 2'-deoxycytidine 1-acyl-sn-glycerol-3- rhodanese domain- succinyl-diaminopimelate glycerol-3-phosphate 1- a tRNA 1-(3-sn- phosphorylase: transferase: 1-acyl-sn-glycerol-3- 3-oxoacyl-ACP reductase: GTPase UDP-N-acetylmuramoyl-L- dehydratase FabZ: phosphate acyltransferase: HMPREF1361_RS00170 containing protein: desuccinylase: protein] reductase: O-acyltransferase PlsY: UDP-N-acetylmuramoyl-L- phosphatidyl) HMPREF1361_RS02415 HMPREF1361_RS13465 phosphate acyltransferase: HMPREF1361_RS07985 ObgE: obgE alanine--D-glutamate ligase: HMPREF1361_RS03665 cytidine deaminase: HMPREF1361_RS04300 HMPREF1361_RS01100 HMPREF1361_RS03340 HMPREF1361_RS05580 HMPREF1361_RS12780 alanine--D-glutamate ligase: -sn-glycerol 1-stearoyl-2-stearoyl-sn isobutanoyl-CoA AMP diphosphate an unsulfurated L,L- HMPREF1361_RS04300 [+ 2 isozymes] [+ 3 isozymes] HMPREF1361_RS07025 3-hydroxyacyl-[acyl- 2-deoxy-α-D- HMPREF1361_RS02385 acyl-carrier protein thiocyanate succinate a [protein]-FMN- a 2-acyl-1-alkyl- a cis-delta11-3- a (3R,9Z)-3-[+ 2 isozymes] 1-oleoyl-sn HMPREF1361_RS07025 3-phosphate AMP phosphate GDP H + carrier-protein] -glycerol 3-phosphate [sulfur carrier] diaminopimelate L-threonine sn-glycerol hydroxyC30:1- -glycerol 3- UDP-N-acetyl- phosphatidylglycerophosphatase ribose 1-phosphate thymidine hydroxy-octadec- dehydratase FabZ: 2'-deoxyuridine 3-phosphate [acp] phosphate glu lys α-D-muramoyl-L- UDP-N-acetyl- A: HMPREF1361_RS09990 phosphopentomutase: 9-enoyl-[acp] α HMPREF1361_RS05595 S-methyl-5'-thioadenosine pyrimidine- alanyl-D-glutamate lys -D-muramoyl-L- an L-1- HMPREF1361_RS02410 an L-glutamyl- alanyl-D-glutamate degradation IV nucleoside a (2E)-dec- phosphatidyl- 37 Glu 2-deoxy-D-ribose phosphorylase: (5Z,8Z,11Z,14Z,17Z)-3- a (9Z)-3- adenine [tRNA ] UDP-N-acetylmuramoyl- 2-enoyl-[acp] S-methyl-5'- 1-palmitoyl-sn- isovalerate sn-glycerol a 1-acyl-sn-glycerol a RNA-DNA hybrid a cis-delta15-3- glu sn-glycerol 5-phosphate deoA a palmitoleoyl-[acp] a palmitoyl-[acp] oxodocosapentaenoyl-CoA oxooctacos- in tRNA val a tRNA UDP-N-acetylmuramoyl- pyrimidine- glycerol 3-phosphate 3-phosphate 3-phosphate oxo-C34:1-[acp] 1 ATP D-ala L-alanyl-D-glutamate- thioadenosine acetate--CoA ligase: ribonuclease HI: 9-enoyl-[acp] D-ala L-alanyl-D-glutamate- decanoyl-[acyl-carrier- 5'-methylthioadenosine/ nucleoside 1-acyl-sn-glycerol-3- glycerol-3-phosphate 1- 3-oxoacyl-[acyl-carrier- 1-acyl-sn-glycerol-3- tRNA1(Val) (adenine(37) -L- lysine ligase: fatty acid elongation -- saturated thymine HMPREF1361_RS00170 HMPREF1361_RS06075 3-oxoacyl-ACP reductase: 3-oxoacyl-ACP reductase: -L- lysine ligase: protein] reductase: deoxyribose- adenosylhomocysteine phosphorylase: phosphate acyltransferase: O-acyltransferase PlsY: protein] reductase: phosphate acyltransferase: -N6)-methyltransferase: D-alanine--D-alanine ligase: HMPREF1361_RS11585 HMPREF1361_RS07985 HMPREF1361_RS07985 adenylate cyclase: HMPREF1361_RS11585 HMPREF1361_RS03670 phosphate aldolase: nucleosidase: deoA HMPREF1361_RS043001-palmitoyl-2- HMPREF1361_RS127801-palmitoyl- HMPREF1361_RS05580 HMPREF1361_RS04300 ribonuclease HII: HMPREF1361_RS04295 HMPREF1361_RS01335 D-alanine--D-alanine ligase: isovaleryl-CoA AMP diphosphate [+ 2 isozymes] [+ 2 isozymes] an N 6 - HMPREF1361_RS04455 UDP-N-acetyl-α-D- HMPREF1361_RS02380 HMPREF1361_RS05430 acyl-carrier protein palmitoleoyl-sn- acyl-carrier protein sn-glycerol (3R,5Z,8Z,11Z,14Z,17Z)-3- HMPREF1361_RS12735 a cis-delta15-3- a cis-delta9-3- HMPREF1361_RS01335 a decanoyl-[acp] an acetoacetyl-[acp] a 1-acyl-2-palmitoyl-sn a nucleoside 5'- methyladenine 37 ile muramoyl-L-alanyl-γ- UDP-N-acetyl-α-D- MTR glycerol 3-phosphate 3-phosphate hydroxydocosapentaenoyl-CoA DNA hydroxyC34:1- hydroxyC28:1- cyclic-AMP isoleucine--tRNA ligase: D-alanyl-D-alanine -glycerol 3-phosphate monophosphate in tRNA val γ D-glyceraldehyde 1 HMPREF1361_RS07070 D-glutamyl-L-lysine D-alanyl-D-alanine muramoyl-L-alanyl- - acetaldehyde [acp] [acp] an L-isoleucyl- D-glutamyl-L-lysine 3-oxoacyl-[acyl-carrier- 3-phosphate uracil 2-deoxy-α- [tRNA Ile ] protein] reductase: D-ribose 1- a tRNA Ile UDP-N-acetylmuramoyl- all-trans- γ UDP-N-acetylmuramoyl- HMPREF1361_RS05580 phosphate 2-carboxy-1,4- 4-( -L-glutamylamino) maltotriose D-arabinofuranose (R)-mevalonate tripeptide--D-alanyl- a palmitoleoyl-[acp] 1-cis-vaccenoyl-sn- undecaprenyl sn-glycerol a stearoyl-[acp] phosphoenol a cis-delta17-3- ser tripeptide--D-alanyl- beta-ketoacyl-[acyl-carrier- a 3-oxoacyl-[acp] naphthoquinol butanoate dADP 5-phosphate diphosphate D- alanine ligase: phosphopentomutase: glycerol-3-phosphate diphosphate 3-phosphate gamma-glutamyl-gamma- alpha-glucosidase: pyruvate oxo-C36:1-[acp] 2-dehydro-3- D- alanine ligase: protein] synthase II: 1-acyl-sn-glycerol-3- 1,4-dihydroxy-2-naphthoate glycerol-3-phosphate 1- diphosphomevalonate L-serine ammonia- HMPREF1361_RS01330 acetyl-CoA HMPREF1361_RS02410 aminobutyrate hydrolase: HMPREF1361_RS08215 pyruvate kinase: 3-oxoacyl-ACP reductase: deoxyphosphooctonate HMPREF1361_RS01330 HMPREF1361_RS05585 phosphate acyltransferase: polyprenyltransferase: O-acyltransferase PlsY: decarboxylase: lyase, iron-sulfur- 2-deoxy-D-ribose HMPREF1361_RS03185 alpha-glucosidase: HMPREF1361_RS09060 HMPREF1361_RS07985 aldolase: UDP-N-acetyl-α-D- a 3- 1-cis-vaccenoyl-HMPREF1361_RS04300 HMPREF1361_RS13470 HMPREF1361_RS127801-stearoyl- HMPREF1361_RS07970 dependent, subunit beta: leu α 5-phosphate HMPREF1361_RS00190 [+ 2 isozymes] HMPREF1361_RS12295 leucine--tRNA ligase: muramoyl-L-alanyl- UDP-N-acetyl- -D- oxododecanoyl- acyl-carrier protein 2-palmitoleoyl-sn- DMKH2-11 acyl-carrier protein sn-glycerol 4-aminobutanoate glu dATP pyruvate a cis-delta17-3- HMPREF1361_RS04580 D-glucopyranose maltose IPP HMPREF1361_RS12190 an L-leucyl- γ-D-glutamyl-L-lysyl- muramoyl-L-alanyl- [acp] 3-oxoacyl-[acyl-carrier- glycerol-3-phosphate 3-phosphate hydroxyC36:1- KDO-8P pyruvate γ-D-glutamyl-L-lysyl- 3-oxoacyl-ACP reductase: deoxyribose- [tRNA Leu ] D-alanyl-D-alanine protein] reductase: purine ribonucleosides degradation phosphate aldolase: [acp] a tRNA Leu D-alanyl-D-alanine HMPREF1361_RS07985 HMPREF1361_RS05580 [+ 2 isozymes] beta-ketoacyl-[acyl-carrier- HMPREF1361_RS02380 [+ 2 isozymes] all-trans- 527 1498 a (3R)-3- protein] synthase II: 1-myristoyl-sn- 2-carboxy-1,4- sn-glycerol a ribonucleoside 1-cis-vaccenoyl-sn- a guanine sn-glycerol a uracil a [protein]- adenosine D-glyceraldehyde a palmitoleoyl-[acp] dodecaprenyl a myristoyl-[acp] formate phosphoenol UDP-N-acetyl- hydroxydodecanoyl- HMPREF1361_RS05585 a (3R)-3- glycerol 3-phosphate naphthoquinol 3-phosphate triphosphate glycerol-3-phosphate dGDP in 16S rRNA 3-phosphate in 16S rRNA L-histidine α undecaprenyl- a 2,3,4-saturated acetaldehyde 3-phosphate diphosphate anaerobic ribonucleoside- pyruvate 16S rRNA -D-muramoyl-L- [acp] hydroxyacyl-[acyl- 1-acyl-sn-glycerol-3- 1,4-dihydroxy-2-naphthoate glycerol-3-phosphate 1- 1-acyl-sn-glycerol-3- glycerol-3-phosphate 1- 16S rRNA (uracil(1498)- γ diphospho-N- fatty acyl-[acp] triphosphate reductase: pyruvate kinase: (guanine(527)-N(7))- histidine kinase: alanyl- -D-glutamyl- 3-hydroxyacyl-[acyl- carrier protein] adenosine deaminase: phosphate acyltransferase: polyprenyltransferase: O-acyltransferase PlsY: phosphate acyltransferase: O-acyltransferase PlsY: N(3))-methyltransferase: val acetylmuramoyl-L- 3-hydroxyacyl-[acyl- HMPREF1361_RS06790 HMPREF1361_RS09060 methyltransferase RsmG: HMPREF1361_RS06620 valine--tRNA ligase: L-lysyl-D-alanine carrier-protein] HMPREF1361_RS05870 1-myristoyl-2-HMPREF1361_RS04300 HMPREF1361_RS13470 HMPREF1361_RS127801-myristoyl- HMPREF1361_RS04300 HMPREF1361_RS12780 HMPREF1361_RS04245 alanyl-γ-D-glutamyl-L- a 2'-deoxyribonucleoside HMPREF1361_RS08980 α ω an N 3 - a [protein]- HMPREF1361_RS07285 an L-valyl- dehydratase FabZ: carrier-protein] acyl-carrier protein palmitoleoyl-sn- DMK-12 acyl-carrier protein sn-glycerol 1,2-dicis-vaccenoyl- an N 7 - 1-C16:0- , - lysyl- D-alanyl-D-alanine 5'-triphosphate dGTP pyruvate methyluracil 1498 N-phospho- [tRNA Val ] undecaprenyldiphospho- HMPREF1361_RS03665 dehydratase FabZ: acetyl-CoA glycerol 3-phosphate 3-phosphate phosphatidate methylguanine 527 dicarboxyl-2- Val HMPREF1361_RS05595 xanthosine adenosine inosine guanosine lysophosphatidate in 16S rRNA L-histidine a tRNA undecaprenyl- muramoylpentapeptide beta-N- 3-hydroxyacyl-[acyl- in 16S rRNA diphospho-N- acetylglucosaminyltransferase: carrier-protein] 3-hydroxyacyl-[acyl- HMPREF1361_RS07030 carrier-protein] acetylmuramoyl-L- ditrans,octacis- dehydratase FabZ: an all-trans- 966 a double-stranded D-gluconate dehydratase FabZ: purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside a 2,3,4-saturated a 2,3,4-saturated 2- 2-carboxy-1,4- an alkylated DNA an unsulfurated a guanine a [protein]-L- alanyl-γ-D-glutamyl- undecaprenyldiphospho- HMPREF1361_RS05595 polyisoprenyl H O diphosphate cys sn-glycerol 3-phosphate oligonucleotide 6-phosphate HMPREF1361_RS03665 phosphorylase: phosphorylase: phosphorylase: phosphorylase: fatty acyl-[acp] lysophosphatidate naphthoquinol 2 [sulfur carrier] in 16S rRNA methionine L-lysyl- D-alanine N-acetyl-(N-acetyl-β-D- diphosphate DNA-3-methyladenine manganese-dependent cysteine desulfurase: 16S rRNA bifunctional 6-phosphogluconate ala undecaprenyldiphospho- a (2E)-dodec- a trans-2- HMPREF1361_RS02415 HMPREF1361_RS02420 HMPREF1361_RS02420 HMPREF1361_RS02420 UTP and CTP dephosphorylation I 1-acyl-sn-glycerol-3- 1,4-dihydroxy-2-naphthoate glycerol-3-phosphate 1- peptide-methionine alanine--tRNA ligase: glucosaminyl)muramoyl- a 2,3,4-saturated glycosylase: inorganic pyrophosphatase: HMPREF1361_RS07270 (guanine(966)-N(2))- oligoribonuclease/PAP dehydrogenase muramoylpentapeptide beta-N- 2-enoyl-[acp] enoyl-[acyl- phosphate acyltransferase: polyprenyltransferase: O-acyltransferase PlsY: (R)-S-oxide reductase: HMPREF1361_RS06090 an L-alanyl- L-alanyl-γ-D-glutamyl-L- fatty acyl-[acp] purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside HMPREF1361_RS04230 HMPREF1361_RS12810 methyltransferase RsmD: phosphatase NrnA: (decarboxylating): acetylglucosaminyltransferase: dodecanoyl-[acyl-carrier- carrier protein] UTP a HMPREF1361_RS043002,3,4-saturated HMPREF1361_RS13470 a DNA containing [+ 3 isozymes] HMPREF1361_RS12780 HMPREF1361_RS02920 Ala phosphorylase: phosphorylase: phosphorylase: phosphorylase: an alkylated a sulfurated HMPREF1361_RS06350 HMPREF1361_RS10060 a protein-L- HMPREF1361_RS09895 [tRNA ] HMPREF1361_RS07030 lysyl-D-alanyl-D-alanine acyl-carrier protein 1,2-diacyl-sn- DMKH an apurinic/ phosphate H + ala an N 2 - Ala ditrans,octacis- protein] reductase: 2 1-(18-hydroxyoleoyl)- a nucleoside 5'- D-ribulose a tRNA 2,3,4-saturated fatty HMPREF1361_RS02420 HMPREF1361_RS02415 HMPREF1361_RS02415 HMPREF1361_RS02415 nucleobase [sulfur carrier] 966 methionine- CTP synthase: glycerol 3-phosphate apyrimidinic site methylguanine 5-phosphate undecaprenyldiphospho- HMPREF1361_RS03670 acyl-[acp]:NAD+ sn-glycrol 3-phosphate monophosphate (R)-S-oxide α HMPREF1361_RS01245 in 16S rRNA N-acetyl-(N- oxidoreductase: -D-ribose- acetylglucosaminyl) ditrans,octacis- a dodecanoyl-[acp] 1-phosphate UMP HMPREF1361_RS03670 CTP muramoyl-L-alanyl-γ-D- undecaprenyldiphospho- thymine degradation 1-stearoyl- all-trans- all-trans- a single- 1-myristoyl- a supercoiled asparagine- phosphopentomutase: multifunctional 2',3'- 2-carboxy-1,4- dihydrolipoamide (R)-mevalonate a D-hexose asn glutamyl-L-lysyl-D-alanine N-acetyl-(N- an oleoyl-[acp] sn-glycerol tridecaprenyl octaprenyl 4-hydroxybenzoate stranded RNA sn-glycerol duplex DNA -tRNA 3-oxoacyl-[acyl-carrier- acyl-ACP thioesterase: HMPREF1361_RS02410 cyclic-nucleotide 2'- naphthoquinol polyribonucleotide 5-phosphate formate GTP acetylglucosaminyl) thymine 3-phosphate1-acyl-sn-glycerol-3- diphosphate 1,4-dihydroxy-2-naphthoate diphosphate 4-hydroxybenzoate dihydrolipoyllysine- 3-phosphate ATP-dependent ligase: asnC an L-asparaginyl- γ protein] reductase: HMPREF1361_RS07240 D-ribose 5- phosphodiesterase/ nucleotidyltransferase: 1-acyl-sn-glycerol-3- anaerobic ribonucleoside- glucokinase: muramoyl-L-alanyl- -D- phosphate acyltransferase: polyprenyltransferase: octaprenyltransferase: residue acetyltransferase: phosphomevalonate kinase: DNA helicase: Asn HMPREF1361_RS05580 phosphate CMP 5'-nucleotidase/ phosphate acyltransferase: triphosphate reductase: HMPREF1361_RS07640 [tRNA ] isoglutaminyl-L-lysyl- HMPREF1361_RS04300 HMPREF1361_RS11940 HMPREF1361_RS06410 HMPREF1361_RS07975 HMPREF1361_RS06270 Asn ditrans,octacis- 1-stearoyl-2- HMPREF1361_RS13470 HMPREF1361_RS11865 tRNA D-alanyl-D-alanine beta-ketoacyl-[acyl-carrier- laurate 5,6-dihydrothymine multifunctional 2',3'- 3'-nucleotidase: 3-octaprenyl-4- a nucleoside a single- HMPREF1361_RS04300 HMPREF1361_RS06790 [+ 3 isozymes] undecaprenyldiphospho- acyl-carrier protein oleoyl-sn-glycerol DMKH2-13 1,2-dimyristoyl- D-hexose 6- protein] synthase II: hydantoinase: cyclic-nucleotide 2'- HMPREF1361_RS10010 hydroxybenzoate diphosphate stranded RNA S-acetyldihydrolipoamide (R)-mevalonate dGTP a single N-acetyl-(N- D-aspartate ligase: 3-phosphate diphosphate sn-glycerol phosphate HMPREF1361_RS05585 HMPREF1361_RS07925 phosphodiesterase/ uridine stranded DNA acetylglucosaminyl) HMPREF1361_RS05925 3-phosphate 5'-nucleotidase/ muramoyl-L-alanyl- ditrans,octacis- vancomycin resistance I 3-(carbamoylamino)- a 3-oxotetradecanoyl- 3'-nucleotidase: asp γ-D-isoglutaminyl- undecaprenyldiphospho- lauroyl-CoA 2-methylpropanoate 1-stearoyl- all-trans- a 2,3,4-saturated an apo-[LYS2 L- methyl β-D-glucoside 1-palmitoyl- aspartate--tRNA ligase: [acp] HMPREF1361_RS10010 an acyl-[acyl- 2-carboxy-1,4- a single [DNA] L-lysyl-D-alanine N-acetyl-(N- sn-glycerol decaprenyl CTP 1,2-diacyl-sn- 2-aminoadipyl- coenzyme A 6-phosphate sn-glycerol HMPREF1361_RS04275 an L-aspartyl- D-alanyl-D-alanine carrier protein] naphthoquinol stranded DNA formate ATP NaMN ATP acetylglucosaminyl) 3-oxoacyl-ACP reductase: cytidine 3-phosphate diphosphate glycerol 3-phosphate carrier-protein] 6-phospho-beta- 3-phosphate DNA polymerase asp D-aspartate ligase: 1-acyl-sn-glycerol-3- 1,4-dihydroxy-2-naphthoate phosphatidate holo-ACP synthase: anaerobic ribonucleoside- [tRNA ] muramoyl-L-alanyl-γ- pyruvate D-alanyl-D-alanine HMPREF1361_RS07985 deoxyribonuclease IV: glucosidase: 1-acyl-sn-glycerol-3- nicotinate-nucleotide asp HMPREF1361_RS05925 phosphate acyltransferase: polyprenyltransferase: cytidylyltransferase: III subunit epsilon: tRNA D-isoglutaminyl-N-(β- (R)-3-amino-2- HMPREF1361_RS01320 HMPREF1361_RS04360 phosphate acyltransferase: triphosphate reductase: dipeptidase: [+ 2 isozymes] HMPREF1361_RS04300 HMPREF1361_RS13470 HMPREF1361_RS05765 a holo-[LYS2 L- HMPREF1361_RS04935 HMPREF1361_RS11265 adenylyltransferase: ditrans,octacis- D-asparatyl)-L-lysyl- D-lactate dehydrogenase: a (3R)-3- methylpropanoate a 1-stearoyl 2- HMPREF1361_RS04300 HMPREF1361_RS06790 HMPREF1361_RS07405 DMKH2-10 a CDP-2,3,4-saturated- 2-aminoadipyl- 3',5'-ADP [+ 3 isozymes] 1-palmitoyl-2- a nucleoside 5'- nicotinate adeninenadD undecaprenyldiphospho- D-alanyl-D-alanine HMPREF1361_RS07395 hydroxytetradecanoyl- phosphatidylglycerol acyl-carrier protein acyl-sn-glycerol a 5'-phosphooligonucleotide β-D-glucose dATP diacylglycerol carrier-protein] MeOH cis-vaccenoyl monophosphate dinucleotide N-acetyl-(N- [acp] biosynthesis II (non-plastidic) 3-phosphate 6-phosphate (R)-lactate D-ala phosphatidate acetylglucosaminyl) 3-hydroxyacyl-[acyl- tyr γ Inorganic Nutrient Metabolism tyrosine--tRNA ligase: muramoyl-L-alanyl- -D- carrier-protein] DHAP isoglutaminyl-N-(β-D- ditrans,octacis- NAD(P)H-dependent 1-palmitoyl- HMPREF1361_RS10870 an L-tyrosyl- D-alanine--(R)-lactate dehydratase FabZ: 1-myristoyl- (11Z,14Z,17Z)-3- an insertion sequence an adenine 22 asparatyl)-L-lysyl-D-alanine undecaprenyldiphospho- glycerol-3-phosphate urea cycle an apo [peptidyl- [EntF L-seryl- sn-glycerol (R)-mevalonate pyruvate Tyr ligase VanA: vanB HMPREF1361_RS03665 a myristoyl-[acp] sn-glycerol DL-allothreonine coenzyme A coenzyme A oxoicosatrienoyl-CoA element IS30 in tRNA [tRNA ] N-acetyl-(N- dehydrogenase: 2-aminoethylphosphonate thiosulfate disproportionation carrier protein] carrier protein] 3-phosphate a tRNA Tyr 3-phosphate1-acyl-sn-glycerol-3- 3-oxoacyl-[acyl-carrier- transposase: tRNA (adenine(22)-N(1))- 3-hydroxyacyl-[acyl- degradation I IV (rhodanese) serine holo-ACP synthase: holo-ACP synthase: 1-acyl-sn-glycerol-3- mevalonate kinase: pyruvate carboxylase: acetylglucosaminyl) HMPREF1361_RS03600 phosphate acyltransferase: protein] reductase: HMPREF1361_RS12150 methyltransferase TrmK: muramoyl-L-alanyl-γ- D-alanyl-D-lactate carrier-protein] arg (2-aminoethyl) hydroxymethyltransferase: glyA HMPREF1361_RS01320 a holoHMPREF1361_RS01320-[EntF phosphate acyltransferase: HMPREF1361_RS07965 HMPREF1361_RS06370 ditrans,octacis- dehydratase FabZ: NAD(P)H-dependent thiosulfate 1,2-dimyristoyl-HMPREF1361_RS04300 a holo [peptidyl- HMPREF1361_RS05580 [+ 7 isozymes] HMPREF1361_RS01180 D-isoglutaminyl-N-(β- phosphonate gly acetaldehyde 3',5'-ADP 3',5'-ADP L-seryl-carrier an insertion HMPREF1361_RS04300 N 1 - undecaprenyldiphospho- HMPREF1361_RS05595 glycerol-3-phosphate 2-aminoethylphosphonate- rhodanese domain- acyl-carrier protein sn-glycerol carrier protein] (3R,11Z,14Z,17Z)-3- 1-palmitoyl- (R)-mevalonate D-asparaginyl)-L-lysyl- protein] 22 oxaloacetate dehydrogenase: -pyruvate transaminase: hydroxyicosatrienoyl-CoA sequence IS30 with 2-myristoyl methyladenine 5-phosphate N-acetyl-(N- D-alanyl-D-alanine a (2E)-tetradec- containing protein: 3-phosphate a tRNA Trp HMPREF1361_RS10125 HMPREF1361_RS05730 integrated transposon phosphatidate in tRNA tryptophan--tRNA ligase: acetylglucosaminyl) ammonium HMPREF1361_RS01100 2-enoyl-[acp] sn-glycerol phosphonoacetaldehyde HMPREF1361_RS03725 an L-tryptophanyl- muramoyl-L-alanyl- 3-phosphate sulfite thiocyanate γ myristoyl-[acyl-carrier- Trp -D-isoglutaminyl- carbamoyl- N-acetyl-D-glucosaminyl-N- a 3-O-acetylated N-acetyl-D- (2Z,4E)-2- [tRNA ] phosphonoacetaldehyde 10 an L-methionyl- a 2'- a [protein]-L- N-(β-D-asparaginyl) a peptidoglycan protein] reductase: glycerol-3-phosphate 1- L-arginino- phosphate synthase: an N - galactosamine hydantoin hydroxyhexa- chorismate trp hydrolase: Met acetylmuramoyl-L-alanyl-D-glutamyl- rhamnogalacturonan I VibB coenzyme A deoxyribonucleoside proline (ω = 180) -L-lysyl-D-alanine dimer (E. faeciums) HMPREF1361_RS03670 O-acyltransferase PlsY: L-ornithine HMPREF1361_RS06010 formyltetrahydrofolate [initiator tRNA ] rhamnogalacturonan succinate HMPREF1361_RS05720 methionyl-tRNA 6-carboxy-L-lysyl-D-alanine 6-phosphateN-acetylglucosamine-6- deoxynucleoside kinase: peptidyl-prolyl cis- 2,4-dienedioate HMPREF1361_RS12780 HMPREF1361_RS06015 LD-carboxypeptidase: acetylesterase: holo-ACP synthase: hydantoinase: 4-oxalocrotonate chorismate mutase: a 1-acyl-sn formyltransferase: phosphate deacetylase: HMPREF1361_RS04965 trans isomerase: a myristoyl-[acp] HMPREF1361_RS05855 HMPREF1361_RS03950 HMPREF1361_RS01320 HMPREF1361_RS07925 tautomerase: HMPREF1361_RS11920 -glycerol 3- carbamoyl acetaldehyde HMPREF1361_RS08695 N-acetyl-D-glucosaminyl-N- HMPREF1361_RS06645 [+ 2 isozymes] HMPREF1361_RS05365 an N-formyl- a rhamnogalacturonan a holo-[VibB aryl- D-galactosamine HMPREF1361_RS05675 a peptidoglycan a peptidoglycan 3-oxoacyl-[acyl-carrier- phosphate phosphate D-ala acetylmuramoyl-L-alanyl-D- acetate 3',5'-ADP a 2'- [+ 5 isozymes] ornithine L-methionyl- a tetrahydrofolate type I carrier protein] acetate 6-phosphate a [protein]-L- (3E)-2-oxohex- prephenate thr tetramer with a met glutamyl-6-carboxy-L-lysine deoxyribonucleoside N-carbamoylglycine threonine--tRNA ligase: dimer (E. faecium protein] reductase: 1-acyl-sn-glycerol-3- carbamoyltransferase: [initiator tRNA ] ω 3-enedioate D,D cross-link 5'-monophosphate proline ( = 0) HMPREF1361_RS05680 , tetrapeptide) HMPREF1361_RS05580 phosphate acyltransferase: HMPREF1361_RS05705 an L-threonyl- (Enterococcus faecium) Thr beta-ketoacyl-[acyl-carrier- HMPREF1361_RS04300 [tRNA ] a 1,2-diacyl- L-citrulline acetyl-CoA Thr protein] synthase II: 4-deoxy-β-D-gluc-4- a 2-O-acetylated 967 1402 a plant a tRNA sn-glycerol a ring-opened 7- a cytosine a cytidine an organic HMPREF1361_RS05585 Secondary Metabolite Degradation enuronosyl-(1,3)-N- rhamnogalacturonan I [EntB aryl- coenzyme A arabinogalactan leu a peptidoglycan 3-phosphate methylguanine in DNA carrier protein] ammonium CO ATP in 16S rRNA in 16S rRNA molecule a peptidoglycan with DNA-formamidopyrimidine acetyl-D-galactosamine rhamnogalacturonan 2 16S rRNA type I tetramer with an a 3-oxohexadecanoyl- phosphatidate glycosyl hydrolase holo-ACP synthase: 16S rRNA (cytosine(1402) arabinogalactan endo- (L-alanyl-γ-D-glutamyl- glycosylase: acetylesterase: carbamate kinase: (cytosine(967)-C(5))- branched-chain amino cytochrome P450: L,D cross-link [acp] cytidylyltransferase: anhydromuropeptides recycling I family 88: HMPREF1361_RS01320 -N(4))-methyltransferase: 1,4-beta-galactosidase: L-lysyl-D-alanyl-D- D-galacturonate HMPREF1361_RS01145 HMPREF1361_RS03950 HMPREF1361_RS05710 methyltransferase RsmB: acid aminotransferase: HMPREF1361_RS04260 (Enterococcus faecium) HMPREF1361_RS05765 2,6-diamino-4- HMPREF1361_RS02060 a rhamnogalacturonan a holo-[EntB aryl- HMPREF1361_RS07005 HMPREF1361_RS02350 ser alanine) pentapeptide 3-oxoacyl-ACP reductase: GlcNAc-1,6- degradation I an apurinic site N-acetyl-D- 4-deoxy-L-threo-hex- acetate 3',5'-ADP carbamoyl HMPREF1361_RS08700 an N 4 - HMPREF1361_RS03675 hydroxy-5-(N-methyl) carrier protein] 967 serine--tRNA ligase: a CDP- within DNA type I phosphate a 5-methylcytosine 1402 4-methyl-2- an alcohol HMPREF1361_RS07985 anhMurNAc- aldehydo-D- formamidopyrimidine galactosamine 4-enopyranuronate methylcytidine a galactotetraose HMPREF1361_RS09015 diacylglycerol γ in 16S rRNA oxopentanoate an L-seryl- [+ 2 isozymes] L-Ala- -D-Glu- galacturonate in 16S rRNA [tRNA ser ] a peptidoglycan with a (3R)-3- CDP-diacylglycerol-- DAP-D-Ala glucuronate isomerase: ser γ Amino Acid Degradation a tRNA (L-alanyl- -D-glutamyl- a peptidoglycan with hydroxyhexadecanoyl- glycerol-3-phosphate 3- HMPREF1361_RS03945 γ a 6-phospho- 1402 L-lysyl-D-alanyl-D- (L-alanyl- -D-glutamyl- [acp] D-tagaturonate a single UDP-N-acetylmuramoyl-L- an L-cysteinyl- a cytidine phosphatidyltransferase: γ β an apo-[aryl- an acyl phosphate arsenate L-lysyl-D-alanyl-D- L-serine degradation stranded DNA alanyl- -D-glutamyl-meso-2,6- -D-galactoside coenzyme A a type IV prepilin Cys thr alanine) pentapeptide 3-hydroxyacyl-[acyl- HMPREF1361_RS08580 L-threonine degradation II L-glutamine degradation I 6-phospho-beta- carrier protein] [tRNA ] in 16S rRNA alanine) pentapeptide tagaturonate reductase: exodeoxyribonuclease VII: diaminopimeloyl-D-alanine carrier-protein] 1-(3-sn- N-acetyl-β-D- L-alanyl-γ-D- LD-carboxypeptidase: galactosidase: holo-ACP synthase: prepilin peptidase: aminoacyl-tRNA hydrolase: 16S rRNA (cytidine(1402) L-threonine 3- arsenate reductase HMPREF1361_RS03935 HMPREF1361_RS06955 -2'-O)-methyltransferase: acylphosphatase: (thioredoxin): dehydratase FabZ: phosphatidyl) glucosamine-1,6- glutamyl-meso-2,6- α HMPREF1361_RS05855 HMPREF1361_RS02335 HMPREF1361_RS01320 HMPREF1361_RS01780 HMPREF1361_RS03075 dehydrogenase: pro ser gln HMPREF1361_RS06960 UDP-N-acetyl- -D-muramoyl- HMPREF1361_RS06775 HMPREF1361_RS11650 HMPREF1361_RS12310 HMPREF1361_RS03665 -sn-glycerol anhydro-N-acetyl- diaminopimeloyl- thr D-galactopyranose a holo-[aryl- a cleaved type Cys proline--tRNA ligase: a peptidoglycan with D-altronate L-serine ammonia- a single-stranded a ribonucleoside L-alanyl-γ-D-glutamyl- D-ala an alcohol 3',5'-ADP a peptide a tRNA cys a 2'-O- HMPREF1361_RS06125 γ 3-phosphate β-D-muramate D-alanine L-threonine 3- carbamoyl- 6-phosphate carrier protein] IV prepilin HMPREF1361_RS05775 an L-prolyl- (L-alanyl- -D-glutamyl- 3-hydroxyacyl-[acyl- lyase, iron-sulfur- oligodeoxyribonucleotide 5'-monophosphate meso-2,6-diaminopimelate methylcytidine 1402 a carboxylate arsenite altronate dehydratase: dehydrogenase: phosphate synthase: aminoacetone [tRNA Pro ] L-lysyl-D-alanyl-D- carrier-protein] phosphatidylglycerophosphatase LD-carboxypeptidase: dependent, subunit beta: HMPREF1361_RS06125 HMPREF1361_RS06010 in 16S rRNA a tRNA Pro alanine) pentapeptide dehydratase FabZ: A: HMPREF1361_RS09990 HMPREF1361_RS05855 HMPREF1361_RS03940 2-aminoprop-HMPREF1361_RS04580 L-2-amino-3- HMPREF1361_RS06015 HMPREF1361_RS05595 an L-1- L-alanyl-γ-D- 2-dehydro- oxobutanoate γ 38- 1,6-anhydro-N- 3-deoxy-D- 2-enoate [+ 5 isozymes] a nascent peptidoglycan with (L- a 7,8-dihydro-8- -L-glutamyl-(S)- a uridine an α(1,5)- Amino Acid Biosynthesis a (2E)-hexadec- phosphatidyl- β glutamyl-meso- an N-modified AsbD acyl- nicotinate PRPP maltose NAD + acetyl- -muramate gluconate glycine C-acetyltransferase: glu alanyl-γ-D-glutamyl-meso-2,6- oxoguanine in DNA coenzyme A trans-1-propenyl- 40 in tRNA L-arabinan sn-glycerol diaminopimelate aminoacyl-[tRNA] carrier protein alpha-N- 2-enoyl-[acp] 2-dehydro-3- HMPREF1361_RS06130 L-asparagine diaminopimeloyl-D-alanine) tetrapeptide DNA-formamidopyrimidine nicotinate L-cysteine RluA family alpha-glucosidase: phenylalanyl-tRNA L-lysine biosynthesis II degradation I LD-carboxypeptidase: aminoacyl-tRNA hydrolase: holo-ACP synthase: glutamyl aminopeptidase: HMPREF1361_RS08215 arabinofuranosidase: NAD kinase: L-cysteine biosynthesis superpathway of L-serine L-asparagine biosynthesis L-alanine biosynthesis I palmitoyl-[acyl-carrier- deoxygluconokinase: glycosylase: phosphoribosyltransferase: pseudouridine synthase: synthetase subunit beta: L-glutamate biosynthesis III uracil degradation I (reductive) HMPREF1361_RS05855 HMPREF1361_RS03075 HMPREF1361_RS01320 HMPREF1361_RS07880 HMPREF1361_RS13810 phe and glycine biosynthesis I protein] reductase: HMPREF1361_RS07995 2-iminopropanoate a nascent peptidoglycan with HMPREF1361_RS01145 HMPREF1361_RS13855 S-trans-1- HMPREF1361_RS06040 alpha-glucosidase: HMPREF1361_RS04465 HMPREF1361_RS14535 VI (from L-methionine) III (tRNA-dependent) N-acetyl-D- gly an N-modified an uncharged an apurinic site 7,8-dihydro- a holo-[AsbD acyl- 3-methyl-2- HMPREF1361_RS03670 asn D-ala (L-alanyl-γ-D-glutamyl-meso- 3',5'-ADP NaMN glu propenyl- [+ 4 isozymes] HMPREF1361_RS00190 [+ 2 isozymes] uracil muramate 6- tRNA 38- α + [+ 2 isozymes] an L-phenylalanyl- asp 3-phospho- 2-oxoglutarate KDGP amino acid within DNA 8-oxoguanine carrier protein] a pseudouridine -L- NADP oxobutanoate phosphate asparaginase: 2,6-diaminopimelate) tripeptide L-cysteine D-glucopyranose [tRNA Phe ] aspartate kinase: met D-glycerate NADP-specific glutamate asp branched-chain amino acyl-[acyl-carrier protein] 40 in tRNA arabinofuranose D-3-phosphoglycerate a palmitoyl-[acp] N-acetylmuramic acid HMPREF1361_RS07245 a tRNA Phe HMPREF1361_RS13655 methionine dehydrogenase: acid aminotransferase: thioesterase pathway bifunctional 2-keto- adenosyltransferase: dehydrogenase: 6-phosphate etherase: L-aspartyl- HMPREF1361_RS07360 HMPREF1361_RS03675 5,6-dihydrouracil 4-hydroxyglutarate pyruvate asp HMPREF1361_RS13780 acyl-ACP thioesterase: HMPREF1361_RS00760 Man GlcNAc -[protein] 3 HMPREF1361_RS12240 an L-aspartyl- an acyl-[acyl- 6 2 7,8-dihydrofolate an N -methyladenine an (S)-2- a dipetide with an N- a [release factor]- uridine 4-phosphate 3-phosphooxypyruvate glu val N-acetyl-D- aldolase/2-keto-3-deoxy- NADPH H + pyridoxal SAM Asn hydantoinase: HMPREF1361_RS07240 (isomer 6A B ) monoglutamate halocarboxylate terminal L-aspartate a protein [tRNA ] carrier protein] 6-phosphogluconate 1,2 1 in DNA L-glutamine biotin ATP aspartate-semialdehyde acyl-ACP thioesterase: glucosamine alpha-1,2-mannosidase: dihydrofolate reductase: DNA-3-methyladenine HAD family hydrolase: dipeptidase PepV: peptide chain release uridine kinase: glutamyl-tRNA(Gln) HMPREF1361_RS07925 aldolase: beta-aspartyl-peptidase: 3-oxoacyl-[acyl-carrier- dehydrogenase: palmitate HMPREF1361_RS07240 6-phosphate HMPREF1361_RS04000 HMPREF1361_RS07600 glycosylase I: HMPREF1361_RS04320 HMPREF1361_RS07895 factor N(5)-glutamine biotin--[acetyl-CoA- HMPREF1361_RS11985 met amidotransferase: N-acetylglucosamine-6- HMPREF1361_RS08000 Man GlcNAc - HMPREF1361_RS10100 protein] reductase: methionine--tRNA ligase: HMPREF1361_RS13660 3-ureidopropanoate a fatty acid β-D-mannopyranose 5 2 [+ 2 isozymes] HMPREF1361_RS13925 [+ 2 isozymes] a proteinogenic methyltransferase: carboxylase] ligase: an L-methionyl- HMPREF1361_RS09525 phosphate deacetylase: [protein] (isomer 5A ) tetrahydropteroyl an apurinic site an (R)-2- asp HMPREF1361_RS05580 UMP HMPREF1361_RS10225 1,2 NADP + 3-methyladenine a halide anion amino acid asp a protein HMPREF1361_RS10375 HMPREF1361_RS08780 L-aspartate- 3-phospho- pyruvate 5 biotinyl-5'- [elongator Asp-tRNA(Asn) ala HMPREF1361_RS06645 mono-L-glutamate within DNA hydroxyacid a [release factor]-N 4-pyridoxolactone elongator Met semialdehyde L-serine adenylate tRNA ] SAH /Glu-tRNA(Gln) D-glucosamine -methyl-L-glutamine tRNA Met 4-hydroxy- amidotransferase: palmitoyl-CoA 6-phosphate 5'-methylthioadenosine/ alanine racemase: mannitol degradation I tetrahydrodipicolinate HMPREF1361_RS00925 β adenosylhomocysteine HMPREF1361_RS01315 -alanine phosphoglucosamine Man GlcNAc -[protein] synthase: gatA D-mannitol 8 2 acetoacetyl-CoA H O acetyl-CoA methyl red [DNA] lysine within (R)-lipoate GSSH sulfite 3-octaprenyl-4- reduced riboflavin (R)-propane- nucleosidase: mutase: (isomer 8A B ) 2 HMPREF1361_RS13675 Carbohydrate Biosynthesis 1,2,3 1,2 gcv protein H hydroxybenzoate 1,2-diol ser HMPREF1361_RS00935 D-ala HMPREF1361_RS08850 1-phosphatemannitol-1-phosphate alpha-1,2-mannosidase: hydroxymethylglutaryl- FMN-dependent exodeoxyribonuclease III: lipoate--protein ligase A: rhodanese domain- 3-octaprenyl-4- Lys (2S,4S)-4- HMPREF1361_RS05430 a tRNA D-glucosamine HMPREF1361_RS04000 CoA synthase: NADH-azoreductase: HMPREF1361_RS05200 containing protein: hydroxybenzoate flavin reductase: lactaldehyde reductase: lysine--tRNA ligase: hydroxy-2,3,4,5- S-ribosyl-L- an L-asparaginyl- UDP-N-acetyl-D- 5-dehydrogenase: Man GlcNAc -[protein] a 2'- a [glycine-cleavageHMPREF1361_RS06845 HMPREF1361_RS03020 serine S-adenosyl-L-methionine cycle I [tRNA Asn ] dTDP-L-rhamnose GDP-mannose biosynthesis UDP-α-D-galactose 1-phosphate superpathway of β-D- HMPREF1361_RS10440 β-D-mannopyranose 7 2 HMPREF1361_RS12445 HMPREF1361_RS13745 HMPREF1361_RS01100 carboxy-lyase: HMPREF1361_RS11355 HMPREF1361_RS08010 an L-lysyl- tetrahydrodipicolinate homocysteine glucosamine biosynthesis I PRPP biosynthesis (isomer 7A B ) N,N-dimethyl-1,4- deoxyribonucleoside [DNA] complex H protein] Lys biosynthesis 1,2 1,2 HMPREF1361_RS10770 [tRNA ] 4-hydroxy- hydroxymethyltransferase: glyA L-ornithine degradation biosynthesis I bifunctional UDP-N- glucuronosides degradation F6P HMG-CoA anthranilate 6 thiosulfate glutathione S-ribosylhomocysteine D-glucopyranose D-glucopyranose Alcohol Degradation phenylenediamine 5'-monophosphate N -lipoyl-L-lysine riboflavin (R)-lactaldehyde lys tetrahydrodipicolinate I (L-proline biosynthesis) α-D- D-ribose 5- acetylglucosamine 2-octaprenylphenol lyase: SAM 6-phosphate 6-phosphate UDP-α-D-glucose a β-D-glucuronoside reductase: gly L-homoserine biosynthesis glucose-6- glucopyranose glucose-6- phosphate diphosphorylase/ HMPREF1361_RS13705 ribose-phosphate UDP-glucose 4- HMPREF1361_RS13670 L-ornithine phosphate 1-phosphate phosphate glucosamine-1-phosphate glycerol and glycerophosphodiester degradation glucose-1-phosphate diphosphokinase: epimerase GalE: glycerol degradation V methionine isomerase: pgi isomerase: pgi N-acetyltransferase GlmU: Man GlcNAc -[protein] γ-L-glutamyl-[(S 1-oleoyl-sn (S)-2,3,4,5- L-homocysteine asp ornithine cyclodeaminase: thymidylyltransferase: HMPREF1361_RS04645 HMPREF1361_RS07665 D-glucopyranuronate 9 2 5-amino-4- PRPP 2-oxoglutarate methyl (indol- palmitoyl-CoA H O prephenate (R)-10- adenosyltransferase: F6P F6P HMPREF1361_RS08635 (isomer 9A B ) )-allyl]-L-cysteine 2 -glycerol 3- tetrahydrodipicolinate HMPREF1361_RS03245 HMPREF1361_RS05160 ribose-phosphate UDP-α-D-galactose a glycerophosphodiester glycerol 1,2,3alpha-1,2-mannosidase:1,2,3 imidazolecarboxyamide 3-yl)acetate Hydroxystearate his HMPREF1361_RS12240 aspartate kinase: dTDP-α-D-glucose N-acetyl-α-D- adenine dihydrolipoamide glutamyl aminopeptidase: carboxylesterase: acyl-CoA thioester phosphate histidine--tRNA ligase: 2,3,4,5-tetrahydropyridine- pro mannose-6-phosphate diphosphokinase: glycerol degradation II HMPREF1361_RS04000 1-acyl-sn-glycerol-3- HMPREF1361_RS13655 glucosamine-- glucosamine glycerol dehydrogenase: phosphoribosyltransferase: dehydrogenase: HMPREF1361_RS07880 HMPREF1361_RS03370 hydrolase: prephenate dehydratase: oleate hydratase: HMPREF1361_RS04270 an L-histidyl- 2,6-dicarboxylate N- dTDP-glucose isomerase, class I: HMPREF1361_RS08640 Man GlcNAc - phosphate acyltransferase: met SAH L-aspartyl- fructose-6-phosphate 1-phosphate glycerophosphoryl diester HMPREF1361_RS10275 β-D-mannopyranose 5 2 HMPREF1361_RS05050 HMPREF1361_RS04640 HMPREF1361_RS07215 HMPREF1361_RS01015 HMPREF1361_RS13200 [tRNA His ] acetyltransferase: 4,6-dehydratase: HMPREF1361_RS10480 PRPP [protein] (isomer 5A ) glu S-allyl-L-cysteine MeOH (indol-3-yl)acetate HMPREF1361_RS04300 4-phosphate aminotransferase: aldehydo-D-glucuronate phosphodiesterase: dihydroxyacetone glycerol 1,2 AICAR NADH CO succinyl-CoA palmitate a tRNA His 5'-methylthioadenosine/ HMPREF1361_RS05150 bifunctional UDP-N- 2 keto- HMPREF1361_RS13665 L-cystathionine L-proline biosynthesis I HMPREF1361_RS10130 D-mannopyranose glycerol HMPREF1361_RS10995 glycerol dehydrogenase: dioleoyl oleate adenosylhomocysteine aspartate-semialdehyde L-alanine biosynthesis III acetylglucosamine phosphatidate phenylpyruvate L-2-acetamido-6- [+ 2 isozymes] dTDP-glucose 6-phosphate glucuronate isomerase: glycerophosphodiester HMPREF1361_RS10275 nucleosidase: dehydrogenase: 4,6-dehydratase: diphosphorylase/ HMPREF1361_RS03945 oxoheptanedioate 5-methyltetrahydropteroyltriglutamate- D-glucosamine phosphomannomutase/ glycerol kinase: phosphodiesterase: dihydroxyacetone glu - homocysteine methyltransferase: HMPREF1361_RS05430 HMPREF1361_RS13660 HMPREF1361_RS00290 glucosamine-1-phosphate cys 6-phosphate phosphoglucomutase: HMPREF1361_RS08265 HMPREF1361_RS07510 DHAP Man GlcNAc -[protein] α-maltose 6'- salicyl-6-hydroxy-2- γ-L-glutamyl-(S)- HMPREF1361_RS02770 N-acetyltransferase GlmU: D-fructuronate 7 2 a tripeptide a double an organic gly glycine--tRNA ligase: glutamate 5-kinase: L-aspartate- cysteine desulfurase: phosphoglucosamine dTDP-4-dehydro- HMPREF1361_RS13520 (isomer 7A B ) phosphate cyclohexene-on-oyl ferroheme b methyl-L-cysteine a 7,8-dihydrofolate L-homocysteine S-ribosyl-L-homocysteine α HMPREF1361_RS08635 1,2 1,2 stranded DNA hydroperoxide HMPREF1361_RS00590 cys HMPREF1361_RS08495 semialdehyde HMPREF1361_RS04650 mutase: 6-deoxy- -D- α-D-mannose D-mannonate alpha-1,2-mannosidase: maltose-6'-phosphate carboxylesterase: peptidase T: ferrochelatase: glutamyl aminopeptidase: γ-L-glutamyl UDP-N-acetyl- sn-glycerol dihydrofolate reductase: alkyl hydroperoxide HMPREF1361_RS00595 N-acetyl-L,L-2,6- [+ 3 isozymes] HMPREF1361_RS08850 glucopyranose 1-phosphate oxidoreductase: HMPREF1361_RS04000 glucosidase: HMPREF1361_RS03370 HMPREF1361_RS01190 HMPREF1361_RS02285 HMPREF1361_RS07880 DNA gyrase subunit A: a glycyl-[tRNA Gly ] 5-phosphate α-D-glucosamine 3-phosphate DHAP Man GlcNAc -[protein] 6-hydroxy-2- HMPREF1361_RS13930 reductase subunit F: ala dTDP-4-dehydrorhamnose HMPREF1361_RS09610 β 6 2 HMPREF1361_RS08915 diaminopimelate D-glucosamine -D-mannopyranose HMPREF1361_RS09340 a proteinogenic 2+ S-methyl- HMPREF1361_RS09625 Gly L-isoleucine biosynthesis V UDP-N-acetylglucosamine glycerol-3-phosphate (isomer 6A B ) D-glucopyranose salicyl alcohol cyclohexen- a dipeptide Fe protoporphyrin IX glu [+ 2 isozymes] a tRNA N-acetyl-diaminopimelate glutamate-5-semialdehyde S-ribosylhomocysteine lyase: 1-phosphate 3,5-epimerase: 1,2 2 D-glucopyranose amino acid L-cysteine L-cysteine biosynthesis I 1-carboxyvinyltransferase: D-mannonate dehydrogenase: 6-phosphate one-carboxylate a negatively deacetylase: dehydrogenase: HMPREF1361_RS05155 UDP-α-D-glucose biosynthesis I a folate an alcohol HMPREF1361_RS13705 L-homoserine bifunctional UDP-N- HMPREF1361_RS03430 HMPREF1361_RS08270 supercoiled DNA HMPREF1361_RS13650 HMPREF1361_RS08490 2-methylbutanoate dTDP-4-dehydro- GDP-α-D-mannose mannonate dehydratase: acetylglucosamine β UDP-N-acetylglucosamine L-glutamate-5- ser acetate--CoA ligase: -L-rhamnose D-glucopyranose HMPREF1361_RS09605 DHAP L,L- diphosphorylase/ 1-carboxyvinyltransferase: Man GlcNAc -[protein] HMPREF1361_RS00170 dTDP-4-dehydrorhamnose 6-phosphate 9 2 GlcMan GlcNAc a [protein]- an organic all-trans- an N-terminal L- adenosyl-cobyrinate an organic semialdehyde serine O-acetyltransferase: phosphomannomutase/ mannonate dehydratase: a peptidoglycan 9 2 met diaminopimelate superpathway of L-asparagine biosynthesis 2-methylbutanoyl- glucosamine-1-phosphate reductase: HMPREF1361_RS01255 (isomer 9A B ) -[protein] glutamyl-[protein] GGPP IPP methionine--tRNA ligase: phosphoglucomutase: HMPREF1361_RS09845 1,2,3 1,2,3 L-cysteine hydroperoxide retinyl palmitate a,c-diamide hydroperoxide HMPREF1361_RS08520 CoA N-acetyltransferase GlmU: UDP-N-acetyl-α- alpha-1,2-mannosidase: muramidase: alpha-1,2-mannosidase: peroxiredoxin: carboxylesterase: glutamyl aminopeptidase: heptaprenyl diphosphate HMPREF1361_RS10225 an L-methionyl- diaminopimelate HMPREF1361_RS05145 HMPREF1361_RS13520 2-dehydro-3- adenosylcobyric epimerase: O-acetyl-L-serine HMPREF1361_RS08635 dTDP-β-L- α-D-glucopyranose D-glucosamine- HMPREF1361_RS04000 HMPREF1361_RS12195 HMPREF1361_RS04000 HMPREF1361_RS09620 HMPREF1361_RS03370 HMPREF1361_RS07880 synthase subunit I: peroxiredoxin: [initiator tRNA Met ] α deoxy-D-gluconate Man GlcNAc -[protein] a N-acetylmuramoyl- D-glucosyl- Man GlcNAc - acid synthase: asp N-acetyl- -D- 1-phosphate enolpyruvate β-D-mannopyranose 8 2 N-acetyl-D- 8 2 an intra- HMPREF1361_RS13445 HMPREF1361_RS09620 initiator tRNA Met HMPREF1361_RS13680 (S)-1-pyrroline- rhamnose (isomer 8A B ) pentapeptide- α(1->3)- α- [protein] (isomer an alcohol palmitate all-trans-retinol a protein glu HMPREF1361_RS10435 all-trans- glucosamine 2-dehydro-3- 1,2,3 2,3 glucosamine protein disulfide meso- 5-carboxylate cysteine synthase A: UTP--glucose-1-phosphate UDP-N- diphosphoundecaprenol D-mannose 8A B ) heptaprenyl (S)-3-methyl-2- 1-phosphate deoxygluconokinase: 1,2,3 1,2 adenosylcobyrate an alcohol HMPREF1361_RS06205 uridylyltransferase: acetylenolpyruvoylglucosamine diaminopimelate pyrroline-5- asparagine synthase asparagine synthase oxopentanoate HMPREF1361_RS07995 diphosphate bifunctional UDP-N- HMPREF1361_RS03605 reductase: diaminopimelate carboxylate reductase: (glutamine-hydrolyzing): (glutamine-hydrolyzing): branched-chain amino acetylglucosamine cys UTP--glucose-1-phosphate HMPREF1361_RS05210 decarboxylase: HMPREF1361_RS08600 HMPREF1361_RS07585 HMPREF1361_RS07585 acid aminotransferase: diphosphorylase/ KDGP Man GlcNAc -[protein] RNase R degradation a DNA containing UDP-N-acetyl- 7 2 an all-trans + HMPREF1361_RS13685 HMPREF1361_RS03675 uridylyltransferase: (isomer 7A B ) an apurinic/ hydrogencarbonate H formate CTP 2-phosphoglycolate kanamycin B DHAP glucosamine-1-phosphate α-D-muramate 1,2,3 3 substrate RNA -retinyl ester pro HMPREF1361_RS10120 bifunctional 2-keto- alpha-1,2-mannosidase: ribonuclease R: apyrimidinic site N-acetyltransferase GlmU: endonuclease III: carboxylesterase: carbonic anhydrase: anaerobic ribonucleoside- phosphoglycolate aminoglycoside 6'- lys asn asn ile 4-hydroxyglutarate HMPREF1361_RS04000 HMPREF1361_RS03375 methylglyoxal synthase: HMPREF1361_RS08635 UDP-α-D-glucose Man GlcNAc -[protein] HMPREF1361_RS06170 HMPREF1361_RS03370 HMPREF1361_RS05975 triphosphate reductase: phosphatase: N-acetyltransferase: aldolase/2-keto-3-deoxy- β-D-mannopyranose 6 2 a nucleoside 5'- HMPREF1361_RS10185 UDP-N-acetyl- (isomer 6A ) a diribonucleotide a 3'-terminal a 5'-phospho- a fatty acid all-trans-retinol H O CO HMPREF1361_RS06790 HMPREF1361_RS01080 HMPREF1361_RS10270 α-D-glucosamine UDP-N-acetyl- 6-phosphogluconate 1,2,3 monophosphate unsaturated sugar [DNA] 2 2 dCTP N6'- α-D-muramoyl- aldolase: glycolate acetylkanamycin-B methylglyoxal L-alanyl-γ-D- HMPREF1361_RS08000 glutamyl-meso-2,6- D-glyceraldehyde pyruvate Man GlcNAc -[protein] diaminopimelate 3-phosphate 8 2 a 5S rRNA an (R)-2- (isomer 8A B ) a ribonucleic acid FMN NAD(P)H H + formate UTP a DNA segment 2-deoxy-D-ribose methylglyoxal 1,2,3 1,3 precursor halocarboxylate Carboxylate Degradation alpha-1,2-mannosidase: ribonuclease M5: ribonuclease PH: HAD family hydrolase: flavin reductase: anaerobic ribonucleoside- ribokinase: glyoxalase: HMPREF1361_RS04000 HMPREF1361_RS10205 HMPREF1361_RS03695 HMPREF1361_RS04320 HMPREF1361_RS11355 recombinase: Man GlcNAc - triphosphate reductase: HMPREF1361_RS10670 HMPREF1361_RS12725 β-D-mannopyranose 5 2 a double-stranded a nucleoside an (R)-2- HMPREF1361_RS01605 L-ascorbate degradation [protein] (isomer 5A ) a mature 5S-rRNA a ribonucleic acid a halide anion NAD(P) + FMNH HMPREF1361_RS06790 [+ 2 isozymes] pyruvate fermentation to acetate IV pyruvate decarboxylation to acetyl CoA 1,2 oligonucleotide diphosphate hydroxyacid 2 dUTP 2-deoxy-D-ribose I (bacterial, anaerobic) a DNA segment in (R)-lactate reverse orientation 5-phosphate a [pyruvate L-ascorbate 6-phosphate pyruvate L-ascorbate 6- dehydrogenase E2 protein] N 6 Man GlcNAc -[protein] 5-dehydro-4-deoxy- phosphate lactonase: 8 2 an (R)-2- a single a ribonucleoside a [lipoyl-carrier + β phosphoenol formate C- pyruvate dehydrogenase (isomer 8A B ) (R)-lipoate a carboxylic ester FMNH NAD -D-allopyranose -lipoyl-L-lysine 1,2,3 2,3 halocarboxylate protein]-L-lysine 2 D-glucuronate pyruvate HMPREF1361_RS09305 (acetyl-transferring) E1 alpha-1,2-mannosidase: stranded DNA triphosphate acetyltransferase: dihydrolipoamide pyruvate HAD family hydrolase: DNA primase: lipoate--protein ligase A: carboxylesterase: flavin reductase: 5-dehydro-4-deoxy-D- 3-keto-L-gulonate 6-phosphate HMPREF1361_RS12800 dehydrogenase: component subunit alpha: HMPREF1361_RS04000 D-ribose pyranase: pyruvate kinase: Man GlcNAc -[protein] HMPREF1361_RS04320 HMPREF1361_RS12515 HMPREF1361_RS06845 HMPREF1361_RS03370 HMPREF1361_RS11355 glucuronate isomerase: HMPREF1361_RS06420 β 7 2 HMPREF1361_RS10675 HMPREF1361_RS09060 HMPREF1361_RS04640 -D-mannopyranose an (S)-2- ssDNA/pppN(pN) a [lipoyl-carrier protein]- + HMPREF1361_RS07990 3-dehydro-L-gulonate- (isomer 7A B ) a halide anion 6 a carboxylate an alcohol H NADH FMN dihydrolipoyl 1,2,3 2 hydroxycarboxylate hybrid N -lipoyl-L-lysine 3-deoxy-D-glycero- 6-phosphate acetyl-CoA formate n -1 β-D-allofuranose dehydrogenase: 2,5-hexodiulosonate pyruvate decarboxylase a [pyruvate a [pyruvate UlaD: ulaD phosphate HMPREF1361_RS06405 acetyltransferase: dehydrogenase dehydrogenase 6 6 Man GlcNAc -protein methyl-esterified L-xylulose 5-phosphate HMPREF1361_RS00855 E2 protein] N dihydrolipoyllysine- E2 protein] N -S- 7 2 an (S)-2- (-)-methyl all-trans- pyruvate 2-oxobutanoate FMNH NADP + sec ethylene glycol (isomer 7A B ) homogalacturonan 2 a tRNA ser -dihydrolipoyl-residue acetyltransferase:acetyldihydrolipoyl- 1,2,3 1 halocarboxylate jasmonate retinyl palmitate L-ribulose-5-phosphate alpha-1,2-mannosidase: pectinesterase: acetyl phosphate L-lysine HMPREF1361_RS06410 L-lysine HAD family hydrolase: acetolactate synthase AlsS: flavin reductase: carboxylesterase: carboxylesterase: serine--tRNA ligase: 3-epimerase: HMPREF1361_RS04000 HMPREF1361_RS03885 lactaldehyde reductase: Man GlcNAc -[protein] HMPREF1361_RS04320 HMPREF1361_RS11025 HMPREF1361_RS11355 HMPREF1361_RS03370 HMPREF1361_RS03370 HMPREF1361_RS09015 HMPREF1361_RS09280 β-D-mannopyranose 6 2 an (S)-2- (S)-2-aceto-2- HMPREF1361_RS08010 acetate kinase: (isomer 6A B ) a halide anion MeOH a homogalacturonan H + NADPH FMN MeOH (-)-jasmonate palmitate a retinol an L-seryl- 1,2 1 hydroxycarboxylate hydroxybutanoate L-ribulose 5-phosphate HMPREF1361_RS04205 [tRNA sec ] glycolaldehyde acetyl-CoA superpathway of acetate utilization and formation L-ribulose-5-phosphate acetate 4-epimerase: araD α acetate α p-nitrophenyl- -D- 2'-deoxycytidine L-ribulose-5-phosphate acetate--CoA ligase: a homogalacturonan an -D-galactoside melibionate stachyose raffinose methylsalicylate carbonic acid galactopyranoside deoxynucleoside kinase: 4-epimerase AraD: araD HMPREF1361_RS00170 endopolygalacturonase: alpha-galactosidase: alpha-galactosidase: alpha-galactosidase: alpha-galactosidase: alpha-galactosidase: carboxylesterase: carbonic anhydrase: acetate kinase: HMPREF1361_RS03895 HMPREF1361_RS00970 HMPREF1361_RS00970 HMPREF1361_RS00970 HMPREF1361_RS00970 HMPREF1361_RS00970 HMPREF1361_RS07960 HMPREF1361_RS04205 HMPREF1361_RS03370 HMPREF1361_RS05975 D-xylulose 5-phosphate D-gluconate degradation a non galactosylated α α α [+ 2 isozymes] a homogalacturonan a homogalacturonan α-D-galactose 4-nitrophenol D-galactopyranose D-gluconate -D-galactose -D-galactose raffinose sucrose -D-galactose MeOH salicylate CO H O galactose acceptor dCMP 2 2 acetyl phosphate acetyl-CoA D-gluconate gluconokinase: HMPREF1361_RS01775 D-gluconate phosphate 6-phosphate acetyltransferase: HMPREF1361_RS00855

an amino an amino L-ascorbate D-mannose D-mannose D-mannose acid acid D-sorbitol D-fructose a sugar 6- an L-sorbose 1-phosphate an L-sorbose 1-phosphate an L-sorbose 1-phosphate an L-sorbose 1-phosphate an L-sorbose 1-phosphate a β- a β- a β- a β- a β- 6-phosphate a branched- a branched- a branched- a branched- 6-phosphate 6-phosphate 6-phosphate a carbohydrate a carbohydrate 6-phosphate 1-phosphate phosphate a sugar 6- D-mannose D-fructose 1-phosphate D-fructose 1-phosphate D-fructose 1-phosphate D-fructose 1-phosphate D-fructose 1-phosphate D-mannose D-glucose 6- D-glucose 6- an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino glucoside 6- glucoside 6- glucoside 6- glucoside 6- glucoside 6- L-ascorbate L-ascorbate D-trehalose D-trehalose a sugar 6- chain chain chain chain D-sorbitol D-sorbitol D-fructose D-fructose D-fructose D-fructose D-fructose D-fructose D-fructose a sugar 6- a sugar 6- a sugar 6- a sugar 6- a sugar 6- a sugar 6- a sugar 6- a sugar 6- a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid ammonium D-glucose D-glucose phosphate phosphate 6-phosphate D-mannose 6-phosphate D-mannose 6-phosphate D-mannose 6-phosphate D-mannose 6-phosphate D-mannose 6-phosphate 6-phosphate phosphate phosphate phosphate phosphate phosphate phosphate phosphate 6-phosphate 6-phosphate 6-phosphate 6-phosphate phosphate ammonium amino acid amino acid amino acid amino acid 6-phosphate 6-phosphate 1-phosphate 1-phosphate 1-phosphate 1-phosphate 1-phosphate 1-phosphate 1-phosphate phosphate phosphate phosphate phosphate phosphate phosphate phosphate phosphate predicted predicted predicted predicted predicted predicted predicted predicted predicted predicted ABC predicted ABC ABC ABC PEP-driven PEP-driven PEP-driven PEP-driven PEP-driven PEP-driven PEP-driven RS11670 RS02815 RS10150 RS02825 RS10570 RS06915 RS09865 RS09870 RS10540 RS10830 RS05350 RS02065 RS09105 transporter of RS11610 RS01820 RS13825 RS03920 transporter of RS13235 RS13240 transporter RS06120 RS01445 RS13580 RS10860 RS11310 RS10215 RS09515 RS05405 RS00725 RS05905 RS00775 RS11890 transporter RS11895 RS04930 RS08160 RS08230 RS04395 RS00765 RS00080 transporter RS13315 RS10565 RS02930 RS07835 RS09700 RS00790 RS00555 RS11880 RS08385 RS00220 RS05400 RS03845 RS13755 RS09960 RS02830 RS10575 RS06905 RS09850 RS00905 RS04945 RS01275 RS10145 RS02820 RS10560 RS03490 RS01270 RS09875 RS10475 RS12345 RS14040 transporter transporter transporter transporter transporter transporter a carbohydrate a carbohydrate of an of an of L- of D-mannose of D-mannose of D-mannose of D-sorbitol of D-fructose of a sugar amino acid amino acid ascorbate ammonium

L-sorbose L-sorbose L-sorbose L-sorbose L-sorbose a branched- a branched- a branched- a branched- a sugar D-mannose D-mannose D-mannose D-mannose D-mannose D-glucose D-glucose a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a β-glucoside a β-glucoside a β-glucoside a β-glucoside a β-glucoside trehalose trehalose a sugar D-glucose D-glucose D-sorbitol D-sorbitol D-sorbitol D-fructose D-fructose D-fructose D-fructose D-fructose D-fructose D-fructose D-fructose a sugar a sugar a sugar a sugar a sugar a sugar a sugar a sugar a sugar D-fructose D-fructose D-fructose D-fructose D-fructose an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino L-ascorbate L-ascorbate L-ascorbate chain chain chain chain phosphate ammonium D-mannose D-mannose D-mannose D-mannose D-mannose acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid acid amino acid amino acid amino acid amino acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.