SDS) for This Product

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Total Enclosures: 3 Simplicity in Water Analysis

Thank you for choosing CHEMetrics, Inc. We appreciate your business. In order to best serve your needs for accurate and complete Safety Data, we offer the following information as supplemental to the attached SDS.

SDS No.: K0603

Version No.: 1.1

Product Name: Aluminum Vacu-vials® Ampoules

Part Nos.: K-0603 Ampoules

Product Descriptions: Vacu-vials Ampoules: Sealed glass ampoules, 13 mm OD, for instrumental colorimetric water analysis. Each Vacu-vial™ ampoule contains approximately 1 mL of liquid reagent sealed under vacuum. Test kits contain 30 ampoules.

Addendum to Section 14 Transport Information: Shipping container markings and labels for this product, as received, may vary from the contents of section 14 of the SDS for one or both of the following reasons: • CHEMetrics has packaged this product as Dangerous Goods in Excepted Quantities according to IATA, US DOT, and IMDG regulations. • CHEMetrics has packaged this product as part of a test kit or reagent set composed of various chemical reagents and elected to ship as UN 3316 Chemical Kit, Hazard Class 9, Packing Group II or III. In case of reshipment, it is the responsibility of the shipper to determine appropriate labels and markings in accordance with applicable transportation regulations.

Additional Information: • “Print Date” = Revision Date (expressed as DD/MM/YYYY) • Test kits and reagents sets may contain additional chemical reagents. See separate SDS(s).

CHEMets®, VACUettes®, Vacu-vials®, and Titrets® are registered trademarks of CHEMetrics Inc.

4295 Catlett Road, Midland, VA 22728  P: 800.356.3072  F: 540.788.4856  www.chemetrics.com Aluminum Vacu-vials Ampoules

CHEMetrics, Inc. Chemwatch Hazard Alert Code: 2 Chemwatch: 9-82596 Issue Date: 14/10/2014 SDS No: K0603 Print Date: 12/03/2015 Version No: 1.1 Initial Date: 15/10/2014 Safety Data Sheet according to OSHA HazCom Standard (2012) requirements S.GHS.USA.EN

SECTION 1 IDENTIFICATION OF THE SUBSTANCE / MIXTURE AND OF THE COMPANY / UNDERTAKING

Product Identifier

Product name Aluminum Vacu-vials Ampoules Synonyms Part No.: K-0603 Ampoules Proper shipping name Not Applicable Chemical formula Not Applicable Other means of Not Available identification CAS number Not Applicable

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses Component of water analysis test kit K-0603

Details of the manufacturer/importer

Registered company name CHEMetrics, Inc. Address 4295 Catlett Road, Midland, VA. 22728 United States Telephone 1-540-788-9026 Fax 1-540-788-4856 Website www.chemetrics.com Email [email protected]

Emergency telephone number

Association / Organisation ChemTel Inc. Emergency telephone 1-800-255-3924 numbers Other emergency telephone +01-813-248-0585 numbers

SECTION 2 HAZARDS IDENTIFICATION

Classification of the substance or mixture

GHS Classification Respiratory Sensitizer Category 1, Skin Sensitizer Category 1

Label elements

GHS label elements

SIGNAL WORD DANGER

Hazard statement(s)

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled H317 May cause an allergic skin reaction

Precautionary statement(s) Prevention

P101 If medical advice is needed, have product container or label at hand. P102 Keep out of reach of children.

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P103 Read label before use. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P280 Wear protective gloves/protective clothing/eye protection/face protection. P284 [In case of inadequate ventilation] wear respiratory protection. P272 Contaminated work clothing should not be allowed out of the workplace.

Precautionary statement(s) Response

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P342+P311 If experiencing respiratory symptoms: Call a POISON CENTER/doctor/physician/first aider P302+P352 IF ON SKIN: Wash with plenty of water and soap P333+P313 If skin irritation or rash occurs: Get medical advice/attention. P362+P364 Take off contaminated clothing and wash it before reuse.

Precautionary statement(s) Storage Not Applicable Precautionary statement(s) Disposal

P501 Dispose of contents/container to authorised chemical landfill or if organic to high temperature incineration

SECTION 3 COMPOSITION / INFORMATION ON INGREDIENTS

Substances See section below for composition of Mixtures

Mixtures

CAS No %[weight] Name 100-97-0 14 hexamine 7732-18-5 86 water

SECTION 4 FIRST AID MEASURES

Description of first aid measures

If this product comes in contact with eyes: Wash out immediately with water. Eye Contact If irritation continues, seek medical attention. Removal of contact lenses after an eye injury should only be undertaken by skilled personnel. If skin contact occurs: Immediately remove all contaminated clothing, including footwear. Skin Contact Flush skin and hair with running water (and soap if available). Seek medical attention in event of irritation. If fumes, aerosols or combustion products are inhaled remove from contaminated area. Inhalation Other measures are usually unnecessary. Immediately give a glass of water. Ingestion First aid is not generally required. If in doubt, contact a Poisons Information Centre or a doctor.

Indication of any immediate medical attention and special treatment needed Treat symptomatically. For acute or short-term repeated exposures to formaldehyde: INGESTION: Patients present early with severe corrosion of the gastro-intestinal tract and systemic effects. Inflammation and ulceration may progress to strictures. Severe acidosis results from rapid conversion of formaldehyde to formic acid. Coma, hypotension, renal failure and apnoea complicate ingestion. Decontaminate by dilution with milk or water containing ammonium acetate; vomiting should be induced. Follow with gastric lavage using a weak ammonia solution (converts formaldehyde to relatively inert pentamethylenetetramine) Gastric lavage is warranted only in first 15 minutes following ingestion. SKIN: Formaldehyde can combine with epidermal protein to produce a hapten-protein couple capable of sensitising T-lymphocytes. Subsequent exposures cause a type IV hypersensitivity reaction (i.e allergic contact dermatitis). [Ellenhorn & Barceloux: Medical Toxicology] For acute or short term repeated exposures to ammonia and its solutions: Mild to moderate inhalation exposures produce headache, cough, bronchospasm, nausea, vomiting, pharyngeal and retrosternal pain and conjunctivitis. Severe inhalation produces laryngospasm, signs of upper airway obstruction (stridor, hoarseness, difficulty in speaking) and, in excessively, high doses, pulmonary oedema. Warm humidified air may soothe bronchial irritation. Test all patients with conjunctival irritation for corneal abrasion (fluorescein stain, slit lamp exam) Dyspneic patients should receive a chest X-ray and arterial blood gases to detect pulmonary oedema.

SECTION 5 FIREFIGHTING MEASURES

Extinguishing media

The product contains a substantial proportion of water, therefore there are no restrictions on the type of extinguishing media which may be used. Choice of extinguishing media should take into account surrounding areas. Though the material is non-combustible, evaporation of water from the mixture, caused by the heat of nearby fire, may produce floating layers of combustible substances.

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In such an event consider: foam. dry chemical powder.

Special hazards arising from the substrate or mixture

Fire Incompatibility None known.

Advice for firefighters

SECTION 6 ACCIDENTAL RELEASE MEASURES

Personal precautions, protective equipment and emergency procedures

Clean up all spills immediately. Avoid breathing vapours and contact with skin and eyes. Minor Spills Control personal contact with the substance, by using protective equipment. Contain and absorb spill with sand, earth, inert material or vermiculite. Wipe up. Moderate hazard. Clear area of personnel and move upwind. Major Spills Alert Fire Brigade and tell them location and nature of hazard. Wear breathing apparatus plus protective gloves. Prevent, by any means available, spillage from entering drains or water course.

Personal Protective Equipment advice is contained in Section 8 of the MSDS.

SECTION 7 HANDLING AND STORAGE

Precautions for safe handling

Avoid all personal contact, including inhalation. Wear protective clothing when risk of exposure occurs. Use in a well-ventilated area. Safe handling Prevent concentration in hollows and sumps. DO NOT enter confined spaces until atmosphere has been checked. Wear impact- and splash-resistant eyewear. Break the ampoule tip only when it is completely immersed in sample. Breaking the tip in air may cause the glass ampoule to shatter. Other information For optimum analytical performance, store in the dark and at room temperature.

Conditions for safe storage, including any incompatibilities

Polyethylene or polypropylene container. Suitable container Packing as recommended by manufacturer. Check all containers are clearly labelled and free from leaks. Hexamine (hexamethylenetetramine): is hygroscopic and heat sensitive is weakly basic in aqueous solution reacts violently with strong oxidisers, sodium peroxide, nitric acid, 1-bromopentaborane(9) (may explode above 194 deg C), cellulose nitrate of high surface area, iodine (deflagrates at 138 deg C), iodoform (may explode above 175 deg C) may form heat-sensitive explosive materials with digold ketenide is incompatible with acids, acid halides, acrylates, alcohols, substituted allyls, aldehydes, alkylene oxides, anhydrides including maleic anhydride, cresols, caprolactam solution, epichlorohydrin, epoxides including butyl glycidyl ether, isocyanates, glycols, halogenated organics, ketones, peroxides, phenols, vinyl acetate may increase explosive sensitivity of nitromethane may generate flammable hydrogen gas on contact with strong reducing agents including hydrides, nitrides and sulfides attacks copper and copper alloys when heated above 200 deg C decomposes producing toxic and corrosive gases including hydrogen cyanide, ammonia and formaldehyde Formaldehyde: Storage incompatibility is a strong reducing agent may polymerise in air unless properly inhibited (usually with methanol up to 15%) and stored at controlled temperatures will polymerize with active organic material such as phenol reacts violently with strong oxidisers, hydrogen peroxide, potassium permanganate, acrylonitrile, caustics (sodium hydroxide, yielding formic acid and flammable hydrogen), magnesium carbonate, nitromethane, nitrogen oxides (especially a elevated temperatures), peroxyformic acid is incompatible with strong acids (hydrochloric acid forms carcinogenic bis(chloromethyl)ether*), amines, ammonia, aniline, bisulfides, gelatin, iodine, magnesite, phenol, some monomers, tannins, salts of copper, iron, silver. acid catalysis can produce impurities: methylal, methyl formate Aqueous solutions of formaldehyde: slowly oxidise in air to produce formic acid attack carbon steel Concentrated solutions containing formaldehyde are: unstable, both oxidising slowly to form formic acid and polymerising; in dilute aqueous solutions formaldehyde appears as monomeric hydrate (methylene

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glycol) - the more concentrated the solution the more polyoxymethylene glycol occurs as oligomers and polymers (methanol and amine-containing compounds inhibit polymer formation) readily subject to polymerisation, at room temperature, in the presence of air and moisture, to form paraformaldehyde (8-100 units of formaldehyde), a solid mixture of linear polyoxymethylene glycols containing 90-99% formaldehyde; a cyclic trimer, trioxane (CH2O3), may also form Flammable and/or toxic gases are generated by the combination of aldehydes with azo, diazo compounds, dithiocarbamates, nitrides, and strong reducing agents *The empirical equation may be used to determine the concentration of bis(chloromethyl)ether (BCME) formed by reaction with HCl: log(BCME)ppb = -2.25 + 0.67• log(HCHO) ppm + 0.77• log(HCl)ppm Assume values for formaldehyde, in air, of 1 ppm and for HCl of 5 ppm, resulting BCME concentration, in air, would be 0.02 ppb.

PACKAGE MATERIAL INCOMPATIBILITIES Not Available

SECTION 8 EXPOSURE CONTROLS / PERSONAL PROTECTION

Control parameters

OCCUPATIONAL EXPOSURE LIMITS (OEL) INGREDIENT DATA Not Available EMERGENCY LIMITS Ingredient Material name TEEL-1 TEEL-2 TEEL-3 hexamine Hexamethylenetetraamine; (Methenamine) 55 mg/m3 610 mg/m3 3600 mg/m3

Ingredient Original IDLH Revised IDLH hexamine Not Available Not Available water Not Available Not Available

Exposure controls

Engineering controls are used to remove a hazard or place a barrier between the worker and the hazard. Well-designed engineering controls can be highly effective in protecting workers and will typically be independent of worker interactions to provide this high level of protection. Appropriate engineering The basic types of engineering controls are: controls Process controls which involve changing the way a job activity or process is done to reduce the risk. Enclosure and/or isolation of emission source which keeps a selected hazard "physically" away from the worker and ventilation that strategically "adds" and "removes" air in the work environment. Ventilation can remove or dilute an air contaminant if designed properly.

Personal protection

Safety glasses with side shields. Chemical goggles. Eye and face protection Contact lenses may pose a special hazard; soft contact lenses may absorb and concentrate irritants. A written policy document, describing the wearing of lenses or restrictions on use, should be created for each workplace or task. This should include a review of lens absorption and adsorption for the class of chemicals in use and an account of injury experience. Skin protection See Hand protection below Wear chemical protective gloves, e.g. PVC. Wear safety footwear or safety gumboots, e.g. Rubber NOTE: Hands/feet protection The material may produce skin sensitisation in predisposed individuals. Care must be taken, when removing gloves and other protective equipment, to avoid all possible skin contact. Contaminated leather items, such as shoes, belts and watch-bands should be removed and destroyed. The selection of suitable gloves does not only depend on the material, but also on further marks of quality which vary from manufacturer to manufacturer. Body protection See Other protection below Overalls. P.V.C. apron. Other protection Barrier cream. Skin cleansing cream. Thermal hazards Not Available

Recommended material(s) Respiratory protection GLOVE SELECTION INDEX Glove selection is based on a modified presentation of the: "Forsberg Clothing Performance Index". The effect(s) of the following substance(s) are taken into account in the computer- generated selection: Aluminum Vacu-vials Ampoules

Material CPI BUTYL A NEOPRENE A VITON A NATURAL RUBBER C

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PVA C

* CPI - Chemwatch Performance Index A: Best Selection B: Satisfactory; may degrade after 4 hours continuous immersion C: Poor to Dangerous Choice for other than short term immersion NOTE: As a series of factors will influence the actual performance of the glove, a final selection must be based on detailed observation. - * Where the glove is to be used on a short term, casual or infrequent basis, factors such as "feel" or convenience (e.g. disposability), may dictate a choice of gloves which might otherwise be unsuitable following long-term or frequent use. A qualified practitioner should be consulted.

SECTION 9 PHYSICAL AND CHEMICAL PROPERTIES

Information on basic physical and chemical properties

Appearance Colorless

Physical state Liquid Relative density (Water = 1) 1.02 Partition coefficient Odour Not Available Not Available n-octanol / water Auto-ignition temperature Odour threshold Not Available Not Available (°C) Decomposition pH (as supplied) 9.3 Not Available temperature Melting point / freezing Not Available Viscosity (cSt) Not Available point (°C) Initial boiling point and Not Available Molecular weight (g/mol) Not Available boiling range (°C) Flash point (°C) Not Applicable Taste Not Available Evaporation rate Not Available Explosive properties Not Available Flammability Not Applicable Oxidising properties Not Available Surface Tension (dyn/cm or Upper Explosive Limit (%) Not Available Not Available mN/m) Lower Explosive Limit (%) Not Available Volatile Component (%vol) Not Available Vapour pressure (kPa) Not Available Gas group Not Available Solubility in water (g/L) Miscible pH as a solution Not Available Vapour density (Air = 1) Not Available VOC g/L Not Available

SECTION 10 STABILITY AND REACTIVITY

Reactivity See section 7 Unstable in the presence of incompatible materials. Chemical stability Product is considered stable. Hazardous polymerisation will not occur. Possibility of hazardous See section 7 reactions Conditions to avoid See section 7 Incompatible materials See section 7 Hazardous decomposition See section 5 products

SECTION 11 TOXICOLOGICAL INFORMATION

Information on toxicological effects

The material is not thought to produce adverse health effects or irritation of the respiratory tract (as classified by EC Directives using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable control measures be used in an occupational setting. Not normally a hazard due to non-volatile nature of product Inhaled The highly irritant properties of ammonia vapour result as the gas dissolves in mucous fluids and forms irritant, even corrosive solutions. Inhalation of the ammonia fumes causes coughing, vomiting, reddening of lips, mouth, nose, throat and conjunctiva while higher concentrations can cause temporary blindness, restlessness, tightness in the chest, pulmonary oedema (lung damage), weak pulse and cyanosis. Inhalation of high concentrations of vapour may cause breathing difficulty, tightness in chest, pulmonary oedema and lung damage. The material has NOT been classified by EC Directives or other classification systems as "harmful by ingestion". This is because of the lack of corroborating Ingestion animal or human evidence. The material is not thought to produce adverse health effects or skin irritation following contact (as classified by EC Directives using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting. Skin Contact Open cuts, abraded or irritated skin should not be exposed to this material Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected. Although the liquid is not thought to be an irritant (as classified by EC Directives), direct contact with the eye may produce transient discomfort characterised Eye by tearing or conjunctival redness (as with windburn).

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Inhaling this product is more likely to cause a sensitisation reaction in some persons compared to the general population. Skin contact with the material is more likely to cause a sensitisation reaction in some persons compared to the general population. Chronic Hexamine (syn: hexamethylenetetramine, HMT, HMTA) is a known skin sensitiser and some individuals develop skin irritation from contact with the solid, vapour or solution.

Aluminum Vacu-vials TOXICITY IRRITATION Ampoules Aluminum Vacu-vials TOXICITY IRRITATION Ampoules

WATER No significant acute toxicological data identified in literature search.

The following information refers to contact allergens as a group and may not be specific to this product. Contact allergies quickly manifest themselves as contact eczema, more rarely as urticaria or Quincke's oedema. The pathogenesis of contact eczema Aluminum Vacu-vials involves a cell-mediated (T lymphocytes) immune reaction of the delayed type. Other allergic skin reactions, e.g. contact urticaria, involve antibody- Ampoules, HEXAMINE mediated immune reactions. The significance of the contact allergen is not simply determined by its sensitisation potential: the distribution of the substance and the opportunities for contact with it are equally important.

Acute Toxicity Carcinogenicity Skin Irritation/Corrosion Reproductivity Serious Eye STOT - Single Exposure Damage/Irritation Respiratory or Skin STOT - Repeated Exposure sensitisation Mutagenicity Aspiration Hazard

Legend: – Data required to make classification available – Data available but does not fill the criteria for classification – Data Not Available to make classification

CMR STATUS Not Applicable

SECTION 12 ECOLOGICAL INFORMATION

Toxicity For Ammonia: Atmospheric Fate: Ammonia reacts rapidly with available acids (mainly sulfuric, nitric, and sometimes hydrochloric acid) to form the corresponding salts. Ammonia is persistent in the air. Aquatic Fate: Biodegrades rapidly to nitrate, producing a high oxygen demand. Non-persistent in water (half-life 2 days). Ecotoxicity: Moderately toxic to fish under normal temperature and pH conditions and harmful to aquatic life at low concentrations.

Persistence and degradability

Ingredient Persistence: Water/Soil Persistence: Air hexamine HIGH HIGH water LOW LOW

Bioaccumulative potential

Ingredient Bioaccumulation hexamine LOW (LogKOW = -4.1536) water LOW (LogKOW = -1.38)

Mobility in soil

Ingredient Mobility hexamine LOW (KOC = 54.7) water LOW (KOC = 14.3)

SECTION 13 DISPOSAL CONSIDERATIONS

Waste treatment methods

Product / Packaging Dispose of according to federal, state, and local regulations. disposal

SECTION 14 TRANSPORT INFORMATION

Labels Required

Marine Pollutant NO

Land transport (DOT): NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS

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Air transport (ICAO-IATA / DGR): NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS

Sea transport (IMDG-Code / GGVSee): NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS

SECTION 15 REGULATORY INFORMATION

Safety, health and environmental regulations / legislation specific for the substance or mixture

hexamine(100-97-0) is found on the following "US TSCA New Chemical Exposure Limits (NCEL)","US Toxic Substances Control Act (TSCA) - Chemical Substance Inventory" regulatory lists water(7732-18-5) is found on the following regulatory "US Toxic Substances Control Act (TSCA) - Chemical Substance Inventory" lists

SECTION 16 OTHER INFORMATION

Other information Classification of the preparation and its individual components has drawn on official and authoritative sources as well as independent review by the Chemwatch Classification committee using available literature references. A list of reference resources used to assist the committee may be found at: www.chemwatch.net/references

The (M)SDS is a Hazard Communication tool and should be used to assist in the Risk Assessment. Many factors determine whether the reported Hazards are Risks in the workplace or other settings. Risks may be determined by reference to Exposures Scenarios. Scale of use, frequency of use and current or available engineering controls must be considered.

This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission from CHEMWATCH. TEL (+61 3) 9572 4700.

end of SDS Simplicity in Water Analysis

Cover Page for Safety Data Sheet

SDS No.: S0600

Version No.: 2.3

Product Name: Activator Solution for Aluminum Vacu-vials® Kit

Part Nos.: A-0600

Product Descriptions: Activator Solution: Plastic bottle, contains approximately 18 mL of liquid reagent. Test kits contain two (2) bottles of Activator Solution.

Additional Information: • “Print Date” = Revision Date (expressed as DD/MM/YYYY) • Test kits and reagents sets may contain additional chemical reagents. See separate SDS(s).

CHEMets®, VACUettes®, Vacu-vials®, and Titrets® are registered trademarks of CHEMetrics Inc.

4295 Catlett Road, Midland, VA 22728  P: 800.356.3072  F: 540.788.4856  www.chemetrics.com Activator Solution for Aluminum Vacu-vials Kit

CHEMetrics, Inc. Chemwatch Hazard Alert Code: 2 Chemwatch: 9-87751 Issue Date: 17/09/2014 SDS No: S0600 Print Date: 12/03/2015 Version No: 2.3 Initial Date: 19/09/2014 Safety Data Sheet according to OSHA HazCom Standard (2012) requirements S.GHS.USA.EN

SECTION 1 IDENTIFICATION OF THE SUBSTANCE / MIXTURE AND OF THE COMPANY / UNDERTAKING

Product Identifier

Product name Activator Solution for Aluminum Vacu-vials Kit Synonyms Part No.: A-0600 Proper shipping name Not Applicable Chemical formula Not Applicable Other means of Not Available identification CAS number Not Applicable

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses Component of water analysis test kit K-0603

Details of the manufacturer/importer

Registered company name CHEMetrics, Inc. Address 4295 Catlett Road, Midland, VA. 22728 United States Telephone 1-540-788-9026 Fax 1-540-788-4856 Website www.chemetrics.com Email [email protected]

Emergency telephone number

Association / Organisation ChemTel Inc. Emergency telephone 1-800-255-3924 numbers Other emergency telephone +01-813-248-0585 numbers

SECTION 2 HAZARDS IDENTIFICATION

Classification of the substance or mixture

GHS Classification Skin Corrosion/Irritation Category 2, Eye Irritation Category 2A, STOT - SE (Resp. Irr.) Category 3

Label elements

GHS label elements

SIGNAL WORD WARNING

Hazard statement(s)

H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation

Precautionary statement(s) Prevention

P101 If medical advice is needed, have product container or label at hand.

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P102 Keep out of reach of children. P103 Read label before use. P271 Use only outdoors or in a well-ventilated area. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P280 Wear protective gloves/protective clothing/eye protection/face protection.

Precautionary statement(s) Response

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312 Call a POISON CENTER/doctor/physician/first aider/if you feel unwell. P337+P313 If eye irritation persists: Get medical advice/attention. P302+P352 IF ON SKIN: Wash with plenty of water and soap P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

Precautionary statement(s) Storage

P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed.

Precautionary statement(s) Disposal

P501 Dispose of contents/container to authorised chemical landfill or if organic to high temperature incineration

SECTION 3 COMPOSITION / INFORMATION ON INGREDIENTS

Substances See section below for composition of Mixtures

Mixtures

CAS No %[weight] Name 7732-18-5 >97 water 64-19-7 <1 acetic acid glacial 3564-18-9 <1 C.I. Mordant Blue 3 Not Available <1 Proprietary ingredient

SECTION 4 FIRST AID MEASURES

Description of first aid measures

If this product comes in contact with the eyes: Wash out immediately with fresh running water. Eye Contact Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by occasionally lifting the upper and lower lids. Seek medical attention without delay; if pain persists or recurs seek medical attention. Removal of contact lenses after an eye injury should only be undertaken by skilled personnel. If skin contact occurs: Immediately remove all contaminated clothing, including footwear. Skin Contact Flush skin and hair with running water (and soap if available). Seek medical attention in event of irritation. If fumes or combustion products are inhaled remove from contaminated area. Lay patient down. Keep warm and rested. Prostheses such as false teeth, which may block airway, should be removed, where possible, prior to initiating first aid procedures. Inhalation Apply artificial respiration if not breathing, preferably with a demand valve resuscitator, bag-valve mask device, or pocket mask as trained. Perform CPR if necessary. Transport to hospital, or doctor, without delay. Immediately give a glass of water. Ingestion First aid is not generally required. If in doubt, contact a Poisons Information Centre or a doctor.

Indication of any immediate medical attention and special treatment needed Treat symptomatically.

SECTION 5 FIREFIGHTING MEASURES

Extinguishing media

There is no restriction on the type of extinguisher which may be used. Use extinguishing media suitable for surrounding area.

Special hazards arising from the substrate or mixture

Fire Incompatibility None known.

Advice for firefighters

Alert Fire Brigade and tell them location and nature of hazard. Fire Fighting

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Wear breathing apparatus plus protective gloves in the event of a fire. Prevent, by any means available, spillage from entering drains or water courses. Use fire fighting procedures suitable for surrounding area. DO NOT approach containers suspected to be hot. Non combustible. Fire/Explosion Hazard Not considered a significant fire risk, however containers may burn. May emit poisonous fumes.May emit corrosive fumes.

SECTION 6 ACCIDENTAL RELEASE MEASURES

Personal precautions, protective equipment and emergency procedures

Personal Protective Equipment advice is contained in Section 8 of the MSDS.

SECTION 7 HANDLING AND STORAGE

Precautions for safe handling

Avoid all personal contact, including inhalation. Wear protective clothing when risk of exposure occurs. Use in a well-ventilated area. Safe handling Prevent concentration in hollows and sumps. DO NOT enter confined spaces until atmosphere has been checked. Wear impact- and splash-resistant eyewear. Other information For optimum analytical performance, store in the dark and at room temperature.

Conditions for safe storage, including any incompatibilities

Polyethylene or polypropylene container. Suitable container Packing as recommended by manufacturer. Check all containers are clearly labelled and free from leaks. Acetic acid: vapours forms explosive mixtures with air (above 39 C.) reacts violently with bases such as carbonates and hydroxides (giving off large quantities of heat), oxidisers, organic amines, acetaldehyde, potassium tert-butoxide Storage incompatibility reacts (sometimes violently), with strong acids, aliphatic amines, alkanolamines, alkylene oxides, epichlorohydrin, acetic anhydride, 2-aminoethanol, ammonia, ammonium nitrate, bromine pentafluoride, chlorosulfonic acid, chromic acid, chromium trioxide, ethylenediamine, ethyleneimine, hydrogen peroxide, isocyanates, oleum, perchloric acid, permanganates, phosphorus isocyanate, phosphorus trichloride, sodium peroxide, xylene attacks cast iron, stainless steel and other metals, forming flammable hydrogen gas attacks many forms of rubber, plastics and coatings

PACKAGE MATERIAL INCOMPATIBILITIES Not Available

SECTION 8 EXPOSURE CONTROLS / PERSONAL PROTECTION

Control parameters

OCCUPATIONAL EXPOSURE LIMITS (OEL) INGREDIENT DATA Source Ingredient Material name TWA STEL Peak Notes US OSHA Permissible acetic acid 25 mg/m3 / Not Not Exposure Levels (PELs) - Acetic acid Not Available glacial 10 ppm Available Available Table Z1 US ACGIH Threshold Limit acetic acid Not TLV® Basis: URT Acetic acid 10 ppm 15 ppm Values (TLV) glacial Available & eye irr; pulm func Acetic acid (aqueous), Ethanoic acid, Glacial acetic acid (pure US NIOSH Recommended acetic acid 25 mg/m3 / 37 mg/m3 / Not compound), Methanecarboxylic acid [Note: Can be found in Not Available Exposure Limits (RELs) glacial 10 ppm 15 ppm Available concentrations of 5-8% in vinegar.]

EMERGENCY LIMITS Ingredient Material name TEEL-1 TEEL-2 TEEL-3 acetic acid glacial Acetic acid Not Available Not Available Not Available

Ingredient Original IDLH Revised IDLH

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water Not Available Not Available acetic acid glacial 1,000 ppm 50 ppm C.I. Mordant Blue 3 Not Available Not Available Proprietary ingredient Not Available Not Available

Exposure controls

Personal protection

Safety glasses with side shields. Chemical goggles. Eye and face protection Contact lenses may pose a special hazard; soft contact lenses may absorb and concentrate irritants. A written policy document, describing the wearing of lenses or restrictions on use, should be created for each workplace or task. This should include a review of lens absorption and adsorption for the class of chemicals in use and an account of injury experience. Skin protection See Hand protection below Wear chemical protective gloves, e.g. PVC. Wear safety footwear or safety gumboots, e.g. Rubber The selection of suitable gloves does not only depend on the material, but also on further marks of quality which vary from manufacturer to manufacturer. Where the chemical is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior Hands/feet protection to the application. The exact break through time for substances has to be obtained from the manufacturer of the protective gloves and.has to be observed when making a final choice. Suitability and durability of glove type is dependent on usage. Body protection See Other protection below Overalls. P.V.C. apron. Other protection Barrier cream. Skin cleansing cream. Thermal hazards Not Available

Recommended material(s) Respiratory protection GLOVE SELECTION INDEX Type AB-P Filter of sufficient capacity. (AS/NZS 1716 & 1715, EN 143:2000 & 149:2001, ANSI Glove selection is based on a modified presentation of the: Z88 or national equivalent) "Forsberg Clothing Performance Index". Where the concentration of gas/particulates in the breathing zone, approaches or exceeds the The effect(s) of the following substance(s) are taken into account in the computer- "Exposure Standard" (or ES), respiratory protection is required. generated selection: Degree of protection varies with both face-piece and Class of filter; the nature of protection Activator Solution for Aluminum Vacu-vials Kit varies with Type of filter.

Material CPI Required Minimum Half-Face Full-Face Powered Air BUTYL A Protection Factor Respirator Respirator Respirator AB-PAPR-AUS / NEOPRENE A up to 10 x ES AB-AUS P2 - Class 1 P2 BUTYL/NEOPRENE C AB-AUS / Class up to 50 x ES - - NAT+NEOPR+NITRILE C 1 P2 NATURAL RUBBER C up to 100 x ES - AB-2 P2 AB-PAPR-2 P2 ^ NATURAL+NEOPRENE C ^ - Full-face NITRILE C A(All classes) = Organic vapours, B AUS or B1 = Acid gasses, B2 = Acid gas or hydrogen NITRILE+PVC C cyanide(HCN), B3 = Acid gas or hydrogen cyanide(HCN), E = Sulfur dioxide(SO2), G = Agricultural chemicals, K = Ammonia(NH3), Hg = Mercury, NO = Oxides of nitrogen, MB = PE C Methyl bromide, AX = Low boiling point organic compounds(below 65 degC) PE/EVAL/PE C PVA C PVC C SARANEX-23 C TEFLON C VITON C

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SECTION 9 PHYSICAL AND CHEMICAL PROPERTIES

Information on basic physical and chemical properties

Appearance Red

Physical state Liquid Relative density (Water = 1) 1.0 Partition coefficient Odour Slight Not Available n-octanol / water Auto-ignition temperature Odour threshold Not Available Not Available (°C) Decomposition pH (as supplied) 2.2 Not Available temperature Melting point / freezing Not Available Viscosity (cSt) Not Available point (°C) Initial boiling point and 100 Molecular weight (g/mol) Not Available boiling range (°C) Flash point (°C) Not Applicable Taste Not Available Evaporation rate Not Available Explosive properties Not Available Flammability Not Applicable Oxidising properties Not Available Surface Tension (dyn/cm or Upper Explosive Limit (%) Not Available Not Available mN/m) Lower Explosive Limit (%) Not Available Volatile Component (%vol) Not Available Vapour pressure (kPa) Not Available Gas group Not Available Solubility in water (g/L) Miscible pH as a solution Not Available Vapour density (Air = 1) Not Available VOC g/L Not Available

SECTION 10 STABILITY AND REACTIVITY

SECTION 11 TOXICOLOGICAL INFORMATION

Information on toxicological effects

The material can cause respiratory irritation in some persons. The body's response to such irritation can cause further lung damage. Not normally a hazard due to non-volatile nature of product Inhaled The material has NOT been classified by EC Directives or other classification systems as "harmful by inhalation". This is because of the lack of corroborating animal or human evidence. The material has NOT been classified by EC Directives or other classification systems as "harmful by ingestion". This is because of the lack of corroborating Ingestion animal or human evidence. This material can cause inflammation of the skin on contact in some persons. The material may accentuate any pre-existing dermatitis condition Skin contact is not thought to have harmful health effects (as classified under EC Directives); the material may still produce health damage following entry Skin Contact through wounds, lesions or abrasions. Open cuts, abraded or irritated skin should not be exposed to this material Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected. Eye This material can cause eye irritation and damage in some persons. Long-term exposure to respiratory irritants may result in disease of the airways involving difficult breathing and related systemic problems. Chronic Substance accumulation, in the human body, may occur and may cause some concern following repeated or long-term occupational exposure.

Activator Solution for TOXICITY IRRITATION Aluminum Vacu-vials Kit Activator Solution for TOXICITY IRRITATION Aluminum Vacu-vials Kit

WATER No significant acute toxicological data identified in literature search.

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Asthma-like symptoms may continue for months or even years after exposure to the material ceases. This may be due to a non-allergenic condition known Activator Solution for as reactive airways dysfunction syndrome (RADS) which can occur following exposure to high levels of highly irritating compound. Key criteria for the Aluminum Vacu-vials Kit, diagnosis of RADS include the absence of preceding respiratory disease, in a non-atopic individual, with abrupt onset of persistent asthma-like symptoms ACETIC ACID GLACIAL, C.I. within minutes to hours of a documented exposure to the irritant. A reversible airflow pattern, on spirometry, with the presence of moderate to severe MORDANT BLUE 3 bronchial hyperreactivity on methacholine challenge testing and the lack of minimal lymphocytic inflammation, without eosinophilia, have also been included in the criteria for diagnosis of RADS. RADS (or asthma) following an irritating inhalation is an infrequent disorder with rates related to the concentration of and duration of exposure to the irritating substance.

Legend: – Data required to make classification available – Data available but does not fill the criteria for classification – Data Not Available to make classification

CMR STATUS Not Applicable

SECTION 12 ECOLOGICAL INFORMATION

Toxicity For Acetic Acid: Acetic acid and its salts (the acetates) can be grouped together because of their close structural relationships, their natural occurrence in plants and animals, and their fundamental role in cell metabolism. Atmospheric Fate: Acetic acid is degraded photochemically in the atmosphere to produce hydroxyl radicals (estimated typical half-life of 22 days). Physical removal of acetates on atmospheric particulates may occur via wet or dry deposition. Aquatic Fate: Natural water will neutralize dilute solutions of acetic acid. Spills of acetic acid on soil will readily biodegrade - the biodegradation rate for acetic acid after 14 days and under aerobic conditions is 74 days.

Persistence and degradability

Ingredient Persistence: Water/Soil Persistence: Air water LOW LOW acetic acid glacial LOW LOW C.I. Mordant Blue 3 HIGH HIGH Proprietary ingredient LOW LOW

Bioaccumulative potential

Ingredient Bioaccumulation water LOW (LogKOW = -1.38) acetic acid glacial LOW (LogKOW = -0.17) C.I. Mordant Blue 3 HIGH (LogKOW = 5.765) Proprietary ingredient LOW (LogKOW = 0.64)

Mobility in soil

Ingredient Mobility water LOW (KOC = 14.3) acetic acid glacial HIGH (KOC = 1) C.I. Mordant Blue 3 LOW (KOC = 1441000) Proprietary ingredient LOW (KOC = 7.857)

SECTION 13 DISPOSAL CONSIDERATIONS

Waste treatment methods

Product / Packaging Dispose of according to federal, state, and local regulations. disposal

SECTION 14 TRANSPORT INFORMATION

Labels Required

Marine Pollutant NO

Land transport (DOT): NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS

Air transport (ICAO-IATA / DGR): NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS

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Sea transport (IMDG-Code / GGVSee): NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS

Transport in bulk according to Annex II of MARPOL 73 / 78 and the IBC code

Source Ingredient Pollution Category IMO MARPOL 73/78 (Annex II) - List of Noxious Liquid acetic acid glacial Z Substances Carried in Bulk

SECTION 15 REGULATORY INFORMATION

Safety, health and environmental regulations / legislation specific for the substance or mixture

water(7732-18-5) is found on the following regulatory "US Toxic Substances Control Act (TSCA) - Chemical Substance Inventory" lists "US - Tennessee Occupational Exposure Limits - Limits For Air Contaminants","US - Idaho - Limits for Air Contaminants","US - Hawaii Air Contaminant Limits","US - California Permissible Exposure Limits for Chemical Contaminants","US - Vermont Permissible Exposure Limits Table Z-1-A Final Rule Limits acetic acid glacial(64-19-7) is for Air Contaminants","US - Oregon Permissible Exposure Limits (Z-1)","US - Michigan Exposure Limits for Air Contaminants","US NIOSH Recommended found on the following Exposure Limits (RELs)","US - Alaska Limits for Air Contaminants","US - Washington Permissible exposure limits of air contaminants","US - Minnesota regulatory lists Permissible Exposure Limits (PELs)","US ACGIH Threshold Limit Values (TLV)","US - Vermont Permissible Exposure Limits Table Z-1-A Transitional Limits for Air Contaminants","US Toxic Substances Control Act (TSCA) - Chemical Substance Inventory","US - Wyoming Toxic and Hazardous Substances Table Z1 Limits for Air Contaminants","US OSHA Permissible Exposure Levels (PELs) - Table Z1" C.I. Mordant Blue 3(3564-18-9) is found on the "US Toxic Substances Control Act (TSCA) - Chemical Substance Inventory" following regulatory lists Proprietary ingredient() is found on the following "Not Applicable" regulatory lists

SECTION 16 OTHER INFORMATION

end of SDS Simplicity in Water Analysis

Cover Page for Safety Data Sheet

SDS No.: S0601

Version No.: 1.1

Product Name: Neutralizer Solution for Aluminum Vacu-vials® Kit

Part Nos.: A-0601

Product Descriptions: Neutralizer Solution: Plastic bottle, contains approximately 5 g of solid chemical. Test kits contain one (1) bottle. Neutralizer Solution packs contain six (6) bottles.

Additional Information: • “Print Date” = Revision Date (expressed as DD/MM/YYYY) • Test kits and reagents sets may contain additional chemical reagents. See separate SDS(s).

CHEMets®, VACUettes®, Vacu-vials®, and Titrets® are registered trademarks of CHEMetrics Inc.

4295 Catlett Road, Midland, VA 22728  P: 800.356.3072  F: 540.788.4856  www.chemetrics.com Neutralizer Solution for Aluminum Vacu-vials Kit

CHEMetrics, Inc. Chemwatch Hazard Alert Code: 3 Chemwatch: 9-78484 Issue Date: 17/09/2014 SDS No: S0601 Print Date: 12/03/2015 Version No: 1.1 Initial Date: 18/09/2014 Safety Data Sheet according to OSHA HazCom Standard (2012) requirements S.GHS.USA.EN

SECTION 1 IDENTIFICATION OF THE SUBSTANCE / MIXTURE AND OF THE COMPANY / UNDERTAKING

Product Identifier

Product name Neutralizer Solution for Aluminum Vacu-vials Kit Synonyms Part No.: A-0601 Proper shipping name Not Applicable Chemical formula Not Applicable Other means of Not Available identification CAS number Not Applicable

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses Component of water analysis test kit K-0603

Details of the manufacturer/importer

Registered company name CHEMetrics, Inc. Address 4295 Catlett Road, Midland, VA. 22728 United States Telephone 1-540-788-9026 Fax 1-540-788-4856 Website www.chemetrics.com Email [email protected]

Emergency telephone number

Association / Organisation ChemTel Inc. Emergency telephone 1-800-255-3924 numbers Other emergency telephone +01-813-248-0585 numbers

SECTION 2 HAZARDS IDENTIFICATION

Classification of the substance or mixture

Skin Corrosion/Irritation Category 2, Serious Eye Damage Category 1, Skin Sensitizer Category 1, STOT - SE (Resp. Irr.) Category 3, Acute Aquatic Hazard GHS Classification Category 3

Label elements

GHS label elements

SIGNAL WORD DANGER

Hazard statement(s)

H315 Causes skin irritation H318 Causes serious eye damage H317 May cause an allergic skin reaction H335 May cause respiratory irritation H402 Harmful to aquatic life

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Precautionary statement(s) Prevention

P101 If medical advice is needed, have product container or label at hand. P102 Keep out of reach of children. P103 Read label before use. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P273 Avoid release to the environment. P272 Contaminated work clothing should not be allowed out of the workplace.

Precautionary statement(s) Response

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310 Immediately call a POISON CENTER/doctor/physician/first aider P302+P352 IF ON SKIN: Wash with plenty of water and soap P333+P313 If skin irritation or rash occurs: Get medical advice/attention. P362+P364 Take off contaminated clothing and wash it before reuse.

Precautionary statement(s) Storage

P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed.

Precautionary statement(s) Disposal

P501 Dispose of contents/container to authorised chemical landfill or if organic to high temperature incineration

SECTION 3 COMPOSITION / INFORMATION ON INGREDIENTS

Substances See section below for composition of Mixtures

Mixtures

CAS No %[weight] Name 7783-20-2 89 Ammonium iron (II) sulfate hexahydrate 70-49-5 11 thiomalic acid

SECTION 4 FIRST AID MEASURES

Description of first aid measures

If this product comes in contact with the eyes: Immediately hold eyelids apart and flush the eye continuously with running water. Eye Contact Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by occasionally lifting the upper and lower lids. Continue flushing until advised to stop by the Poisons Information Centre or a doctor, or for at least 15 minutes. Transport to hospital or doctor without delay. Removal of contact lenses after an eye injury should only be undertaken by skilled personnel. If skin contact occurs: Immediately remove all contaminated clothing, including footwear. Skin Contact Flush skin and hair with running water (and soap if available). Seek medical attention in event of irritation. If fumes or combustion products are inhaled remove from contaminated area. Lay patient down. Keep warm and rested. Prostheses such as false teeth, which may block airway, should be removed, where possible, prior to initiating first aid procedures. Inhalation Apply artificial respiration if not breathing, preferably with a demand valve resuscitator, bag-valve mask device, or pocket mask as trained. Perform CPR if necessary. Transport to hospital, or doctor, without delay. IF SWALLOWED, REFER FOR MEDICAL ATTENTION, WHERE POSSIBLE, WITHOUT DELAY. For advice, contact a Poisons Information Centre or a doctor. Urgent hospital treatment is likely to be needed. In the mean time, qualified first-aid personnel should treat the patient following observation and employing supportive measures as indicated by the patient's condition. If the services of a medical officer or medical doctor are readily available, the patient should be placed in his/her care and a copy of the MSDS should be provided. Further action will be the responsibility of the medical specialist. If medical attention is not available on the worksite or surroundings send the patient to a hospital together with a copy of the MSDS. Ingestion Where medical attention is not immediately available or where the patient is more than 15 minutes from a hospital or unless instructed otherwise: INDUCE vomiting with fingers down the back of the throat, ONLY IF CONSCIOUS. Lean patient forward or place on left side (head-down position, if possible) to maintain open airway and prevent aspiration. NOTE: Wear a protective glove when inducing vomiting by mechanical means.

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Indication of any immediate medical attention and special treatment needed As in all cases of suspected poisoning, follow the ABCDEs of emergency medicine (airway, breathing, circulation, disability, exposure), then the ABCDEs of toxicology (antidotes, basics, change absorption, change distribution, change elimination). For poisons (where specific treatment regime is absent): ------BASIC TREATMENT ------Establish a patent airway with suction where necessary. Watch for signs of respiratory insufficiency and assist ventilation as necessary. Administer oxygen by non-rebreather mask at 10 to 15 L/min. Monitor and treat, where necessary, for pulmonary oedema. Monitor and treat, where necessary, for shock. Anticipate seizures. DO NOT use emetics. Where ingestion is suspected rinse mouth and give up to 200 ml water (5 ml/kg recommended) for dilution where patient is able to swallow, has a strong gag reflex and does not drool. ------ADVANCED TREATMENT ------Consider orotracheal or nasotracheal intubation for airway control in unconscious patient or where respiratory arrest has occurred. Positive-pressure ventilation using a bag-valve mask might be of use. Monitor and treat, where necessary, for arrhythmias. Start an IV D5W TKO. If signs of hypovolaemia are present use lactated Ringers solution. Fluid overload might create complications. Drug therapy should be considered for pulmonary oedema. Hypotension with signs of hypovolaemia requires the cautious administration of fluids. Fluid overload might create complications. Treat seizures with diazepam. Proparacaine hydrochloride should be used to assist eye irrigation. BRONSTEIN, A.C. and CURRANCE, P.L. EMERGENCY CARE FOR HAZARDOUS MATERIALS EXPOSURE: 2nd Ed. 1994 Treat symptomatically.

SECTION 5 FIREFIGHTING MEASURES

Extinguishing media

There is no restriction on the type of extinguisher which may be used. Use extinguishing media suitable for surrounding area.

Special hazards arising from the substrate or mixture

Fire Incompatibility Avoid contamination with oxidising agents i.e. nitrates, oxidising acids, chlorine bleaches, pool chlorine etc. as ignition may result

Advice for firefighters

Alert Fire Brigade and tell them location and nature of hazard. Wear breathing apparatus plus protective gloves in the event of a fire. Fire Fighting Prevent, by any means available, spillage from entering drains or water courses. Use fire fighting procedures suitable for surrounding area. DO NOT approach containers suspected to be hot. Solid which exhibits difficult combustion or is difficult to ignite. Avoid generating dust, particularly clouds of dust in a confined or unventilated space as dusts may form an explosive mixture with air, and any source of ignition, i.e. flame or spark, will cause fire or explosion. Dust clouds generated by the fine grinding of the solid are a particular hazard; accumulations of fine dust (420 micron or less) may burn rapidly and fiercely Fire/Explosion Hazard if ignited; once initiated larger particles up to 1400 microns diameter will contribute to the propagation of an explosion. A dust explosion may release large quantities of gaseous products; this in turn creates a subsequent pressure rise of explosive force capable of damaging plant and buildings and injuring people. Usually the initial or primary explosion takes place in a confined space such as plant or machinery, and can be of sufficient force to damage or rupture the plant.

SECTION 6 ACCIDENTAL RELEASE MEASURES

Personal precautions, protective equipment and emergency procedures

Remove all ignition sources. Clean up all spills immediately. Minor Spills Avoid contact with skin and eyes. Control personal contact with the substance, by using protective equipment. Use dry clean up procedures and avoid generating dust. Moderate hazard. CAUTION: Advise personnel in area. Major Spills Alert Emergency Services and tell them location and nature of hazard. Control personal contact by wearing protective clothing. Prevent, by any means available, spillage from entering drains or water courses.

Personal Protective Equipment advice is contained in Section 8 of the MSDS.

SECTION 7 HANDLING AND STORAGE

Precautions for safe handling

The careful design and assembly of equipment is paramount to the control of mercaptan odors. Although careful planning reduces the chances for leaks developing in the system, it is important to be prepared to locate and stop small leaks promptly. It is recommended that a leak check be made prior to every run Safe handling carried out under pressure in metal equipment with a mercaptan or hydrogen sulfide present. An effective method to obtain a leak-free system involves two steps:

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1. Charge the system with nitrogen gas or other inert, nontoxic gas to a pressure at least as high as will be used in practice, and check for a drop in pressure with time on a suitable gauge. In some cases, it is advantageous to block off sections of the system to facilitate finding the leak. .Wear impact- and splash-resistant eyewear Store in original containers. Keep containers securely sealed. Store in a cool, dry area protected from environmental extremes. Other information Store away from incompatible materials and foodstuff containers. Protect containers against physical damage and check regularly for leaks. For optimum analytical performance, store in the dark and at room temperature.

Conditions for safe storage, including any incompatibilities

Glass container is suitable for laboratory quantities Suitable container Polyethylene or polypropylene container. Check all containers are clearly labelled and free from leaks. Ammonium sulfate: is strongly acid in aqueous solution reacts with caustics forming ammonia reacts violently with potassium chlorate when hot reacts with nitrates, nitrites, chlorates attacks metals Storage incompatibility is incompatible with sulfuric acid, aliphatic amines, alkanolamines, amides, organic anhydrides, isocyanates, vinyl acetate, alkylene oxides, epichlorohydrin, potassium plus ammonium nitrate, sodium-potassium powder plus ammonium nitrate mixtures with sodium hypochlorite form unstable, explosive nitrogen trichloride Reacts with mild steel, galvanised steel / zinc producing hydrogen gas which may form an explosive mixture with air. Avoid strong bases. Avoid reaction with oxidising agents

PACKAGE MATERIAL INCOMPATIBILITIES Not Available

SECTION 8 EXPOSURE CONTROLS / PERSONAL PROTECTION

Control parameters

OCCUPATIONAL EXPOSURE LIMITS (OEL) INGREDIENT DATA Not Available EMERGENCY LIMITS Ingredient Material name TEEL-1 TEEL-2 TEEL-3 Neutralizer Solution for Not Available Not Available Not Available Not Available Aluminum Vacu-vials Kit

Ingredient Original IDLH Revised IDLH Ammonium iron (II) sulfate Not Available Not Available hexahydrate thiomalic acid Not Available Not Available

Exposure controls

Personal protection

Safety glasses with side shields. Chemical goggles. Eye and face protection Contact lenses may pose a special hazard; soft contact lenses may absorb and concentrate irritants. A written policy document, describing the wearing of lenses or restrictions on use, should be created for each workplace or task. This should include a review of lens absorption and adsorption for the class of chemicals in use and an account of injury experience. Skin protection See Hand protection below NOTE: The material may produce skin sensitisation in predisposed individuals. Care must be taken, when removing gloves and other protective equipment, to avoid all possible skin contact. Hands/feet protection Contaminated leather items, such as shoes, belts and watch-bands should be removed and destroyed. The selection of suitable gloves does not only depend on the material, but also on further marks of quality which vary from manufacturer to manufacturer. Where the chemical is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the application. Body protection See Other protection below

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Overalls. P.V.C. apron. Other protection Barrier cream. Skin cleansing cream. Thermal hazards Not Available

Recommended material(s) Respiratory protection GLOVE SELECTION INDEX Particulate. (AS/NZS 1716 & 1715, EN 143:000 & 149:001, ANSI Z88 or national equivalent) Glove selection is based on a modified presentation of the: "Forsberg Clothing Performance Index". Required Minimum Half-Face Full-Face Powered Air The effect(s) of the following substance(s) are taken into account in the computer- Protection Factor Respirator Respirator Respirator generated selection: P1 - PAPR-P1 Neutralizer Solution for Aluminum Vacu-vials Kit Not Available up to 10 x ES Air-line* - - Material CPI up to 50 x ES Air-line** P2 PAPR-P2

* CPI - Chemwatch Performance Index up to 100 x ES - P3 - A: Best Selection Air-line* - B: Satisfactory; may degrade after 4 hours continuous immersion C: Poor to Dangerous Choice for other than short term immersion 100+ x ES - Air-line** PAPR-P3 NOTE: As a series of factors will influence the actual performance of the glove, a final selection must be based on detailed observation. - * - Negative pressure demand ** - Continuous flow * Where the glove is to be used on a short term, casual or infrequent basis, factors such as A(All classes) = Organic vapours, B AUS or B1 = Acid gasses, B2 = Acid gas or hydrogen "feel" or convenience (e.g. disposability), may dictate a choice of gloves which might otherwise cyanide(HCN), B3 = Acid gas or hydrogen cyanide(HCN), E = Sulfur dioxide(SO2), G = be unsuitable following long-term or frequent use. A qualified practitioner should be consulted. Agricultural chemicals, K = Ammonia(NH3), Hg = Mercury, NO = Oxides of nitrogen, MB = Methyl bromide, AX = Low boiling point organic compounds(below 65 degC)

SECTION 9 PHYSICAL AND CHEMICAL PROPERTIES

Information on basic physical and chemical properties

Appearance White

Physical state Solid Relative density (Water = 1) Not Available Partition coefficient Odour Sharp Not Available n-octanol / water Auto-ignition temperature Odour threshold Not Available Not Available (°C) Decomposition pH (as supplied) Not Available Not Available temperature Melting point / freezing Not Available Viscosity (cSt) Not Available point (°C) Initial boiling point and Not Available Molecular weight (g/mol) Not Available boiling range (°C) Flash point (°C) Not Applicable Taste Not Available Evaporation rate Not Available Explosive properties Not Available Flammability Not Applicable Oxidising properties Not Available Surface Tension (dyn/cm or Upper Explosive Limit (%) Not Available Not Applicable mN/m) Lower Explosive Limit (%) Not Available Volatile Component (%vol) Not Available Vapour pressure (kPa) Not Available Gas group Not Available Solubility in water (g/L) Miscible pH as a solution Not Available Vapour density (Air = 1) Not Available VOC g/L Not Available

SECTION 10 STABILITY AND REACTIVITY

SECTION 11 TOXICOLOGICAL INFORMATION

Information on toxicological effects

The material can cause respiratory irritation in some persons. The body's response to such irritation can cause further lung damage. Inhaled Thiols (particularly ethyl mercaptan) produce lethargy or sleepiness. Exposure to high levels may result in nausea, vomiting, restlessness, muscle

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incoordination and/or paralysis, bluing of skin, depression of breathing, coma and death. Prolonged exposure may cause headache, nausea and ultimately loss of consciousness. Accidental ingestion of the material may be harmful; animal experiments indicate that ingestion of less than 150 gram may be fatal or may produce serious Ingestion damage to the health of the individual. Sulfates are not well absorbed orally, but can cause diarrhoea. This material can cause inflammation of the skin on contact in some persons. The material may accentuate any pre-existing dermatitis condition Skin Contact Open cuts, abraded or irritated skin should not be exposed to this material Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected. Eye If applied to the eyes, this material causes severe eye damage. Long-term exposure to respiratory irritants may result in disease of the airways involving difficult breathing and related systemic problems. Skin contact with the material is more likely to cause a sensitisation reaction in some persons compared to the general population. Chronic Substance accumulation, in the human body, may occur and may cause some concern following repeated or long-term occupational exposure. There is some evidence that inhaling this product is more likely to cause a sensitisation reaction in some persons compared to the general population.

Neutralizer Solution for TOXICITY IRRITATION Aluminum Vacu-vials Kit Neutralizer Solution for TOXICITY IRRITATION Aluminum Vacu-vials Kit

The following information refers to contact allergens as a group and may not be specific to this product. Contact allergies quickly manifest themselves as contact eczema, more rarely as urticaria or Quincke's oedema. The pathogenesis of contact eczema Neutralizer Solution for involves a cell-mediated (T lymphocytes) immune reaction of the delayed type. Other allergic skin reactions, e.g. contact urticaria, involve antibody- Aluminum Vacu-vials Kit mediated immune reactions. The significance of the contact allergen is not simply determined by its sensitisation potential: the distribution of the substance and the opportunities for contact with it are equally important.

Asthma-like symptoms may continue for months or even years after exposure to the material ceases. This may be due to a non-allergenic condition known as reactive airways dysfunction syndrome (RADS) which can occur following exposure to high levels of highly irritating compound. Key criteria for the diagnosis of RADS include the absence of preceding respiratory disease, in a non-atopic individual, with abrupt onset of persistent asthma-like symptoms THIOMALIC ACID within minutes to hours of a documented exposure to the irritant. A reversible airflow pattern, on spirometry, with the presence of moderate to severe bronchial hyperreactivity on methacholine challenge testing and the lack of minimal lymphocytic inflammation, without eosinophilia, have also been included in the criteria for diagnosis of RADS. RADS (or asthma) following an irritating inhalation is an infrequent disorder with rates related to the concentration of and duration of exposure to the irritating substance.

Legend: – Data required to make classification available – Data available but does not fill the criteria for classification – Data Not Available to make classification

CMR STATUS Not Applicable

SECTION 12 ECOLOGICAL INFORMATION

Toxicity Harmful to aquatic organisms. for ammonium sulfate Environmental fate: Based on the physico-chemical properties of ammonium sulfate, water is expected to be the main target compartment. Although ammonium sulfate can be created in the atmosphere from ammonia and sulfur dioxide, this process is limited by atmospheric sulfur dioxide, not by ammonia, which has many natural sources. Particulate ammonium sulfate is removed from air by wet and dry deposition. There is no evidence for photodegradation of ammonium sulfate.

Persistence and degradability

Ingredient Persistence: Water/Soil Persistence: Air thiomalic acid LOW LOW

Bioaccumulative potential

Ingredient Bioaccumulation thiomalic acid LOW (LogKOW = -0.8841)

Mobility in soil

Ingredient Mobility thiomalic acid LOW (KOC = 10.44)

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SECTION 13 DISPOSAL CONSIDERATIONS

Waste treatment methods

Product / Packaging Dispose of according to federal, state, and local regulations. disposal

SECTION 14 TRANSPORT INFORMATION

Labels Required

Marine Pollutant NO

Land transport (DOT): NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS

Air transport (ICAO-IATA / DGR): NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS

Sea transport (IMDG-Code / GGVSee): NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS

SECTION 15 REGULATORY INFORMATION

Safety, health and environmental regulations / legislation specific for the substance or mixture

Ammonium iron (II) sulfate hexahydrate(7783-20-2) is "Not Applicable" found on the following regulatory lists thiomalic acid(70-49-5) is found on the following "US Toxic Substances Control Act (TSCA) - Chemical Substance Inventory" regulatory lists

SECTION 16 OTHER INFORMATION

end of SDS