IBA PROTON THERAPY CENTERS AROUND THE WORLD

NORTH AMERICA NETWORK

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Northwestern Medicine Chicago Proton Therapy Center LLC (TPTC) Oklahoma Procure Treatment Center SCCA Proton Therapy Procure Center Proton Center ProVision Healthcare Oklahoma City, OK, USA Seattle, Wa, USA Warrenville, USA Knoxville, USA Treating since 2009 Treating since 2013 Treating since 2010 Treating since 2014 Proteus®PLUS Proteus®PLUS Proteus®PLUS Proteus®PLUS • Gantry Treatment Room • Gantry Treatment Room • Gantry Treatment Room • Gantry Treatment Rooms (2) • Fixed-Beam Treatment Room • Fixed-Beam Treatment Room • Fixed-Beam Treatment Room • Fixed-Beam Treatment Room • 2 Dual Beam Line Treatment Rooms (Horizontal and Incline • Inclined-Beam Treatment Rooms (2) • Horizontal and Inclined beam line Treatment Rooms (2) http://provisionha.com/partners/partner/ d BTR) https://www.sccaprotontherapy.com http://www.chicagoprotoncenter.com provision-center-for-proton-therapy https://www.procure.com/Oklahoma-Explore

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University of Pennsylvania Health Texas Center for Proton Therapy Willis Knighton Medical Center University of Florida Proton System Roberts Proton Therapy Dallas, USA Shreveport, USA Therapy Institute Center Treating since 2015 Treating since 2014 Jacksonville, FL, USA Philadelphia, PA, USA Treating since 2006 Treating since 2010 Proteus®PLUS Proteus®ONE • 2 Gantry Treatment Rooms (incl. CBCT) • including CBCT Proteus®PLUS Proteus®PLUS • Fixed-Beam Treatment Room http://www.wkhs.com/Cancer/Cancer-Treatm • Gantry Treatment Rooms (3) • Gantry Treatment rooms incl. CBCT (4) http://www.texascenterforprotontherapy.c ent-Services/Proton-Therapy.aspx • Small Fixed Beam Treatment room (Eye-Line) • Fixed-Beam Treatment Room om/ https://www.floridaproton.org • Research Room http://www.pennprotontherapy.org 1 5 4 3 ROOMS ROOMS ROOMS ROOMS

University of Florida Proton Hampton University Proton Therapy ProCure Proton Therapy Center Massachusetts General Hospital Therapy Institute Institute Somerset, NJ, USA Burr Proton Therapy Center Jacksonville, FL, USA Hampton, VA, USA Treating since 2012 Boston, USA Opening in 2018 Treating since 2010 Treating since 2001 Proteus®PLUS Proteus®ONE Proteus®PLUS • Gantry Treatment Room Proteus®PLUS • incl. Cone Beam CT • Gantry Treatment Rooms (4) • Fixed-Beam Treatment Room • 2 Gantry Treatment rooms https://www.floridaproton.org • Fixed-Beam Treatment Room • Horizontal and Inclined Beam Treatment Rooms (2) • Research port http://www.hamptonproton.org https://www.procure.com/New-Jersey-Explo • Fixed Beam Treatment room was provided by MGH re http://www.massgeneral.org/radiationonco logy

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Beaumont Health System Baptist Health South Florida Centro de Protonterapia y Detroit, Royal Oak, U.S.A Miami, USA Técnicas Avanzadas de Tratamiento Opening in 2017 Opening in 2018 Buenos Aires, Argentina Opening in 2018 Proteus®ONE Proteus®PLUS • 3 Gantry Treatment Rooms (Pencil Beam Scanning) Proteus®PLUS • Gantry treatment room (PBS Dedicated Nozzle) • Research room • Cone Beam CT EUROPE NETWORK

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APSS Azienda Provinciale per I Proton Therapy Center Czech IFJPAN Universitatklinikum Carl Gustav Servizi Santari Prague, Czech Republic Krakow, Poland Carus Trento, Italy Treating since 2012 Treating since 2011 Dresden, Germany Treating since 2014 Treating since 2014 Proteus®PLUS Proteus®PLUS Proteus®PLUS • Gantry Treatment Rooms (3) • Cone Beam CT (CBCT) Proteus®PLUS • Gantry Treatment Rooms (2) incl. Siemens CT-on-rails. • Fixed-Beam Treatment Room • Fixed-Beam Treatment Room (2) • Gantry Treatment Room https://www.apss.tn.it http://www.proton-cancer-treatment.com http://ccb.ifj.edu.pl/en/index.php • Research room https://www.uniklinikum-dresden.de/de

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Westdeutsches Protonentherapie Skandion Kliniken Institut Curie Centre Antoine Lacassagne zentrum Essen (WPE) Uppsala, Sweden Orsay, France Nice, France Essen, Germany Treating since 2015 Treating since 2009 Opening in 2016 Treating since 2013 Proteus®PLUS Proteus®PLUS Proteus®ONE Proteus®PLUS • Gantry Treatment Rooms (2) • Gantry Treatment Room http://www.centreantoinelacassagne.org/f • Gantry Treatment Rooms (3) • Research room • Connection to existing beam line r/portail-anglais.html • Fixed-Beam Treatment Room http://www.skandionkliniken.se/index.php • Existing Treatment Rooms (2) • Eye Line ?page=english-2 http://protontherapie.curie.fr/fr/la-pro https://www.wpe-uk.de/?lang=en tontherapie 4 1 2 1 ROOMS ROOMS ROOMS ROOMS

Federal High-Technology Center for Cyclhad (Cyclotron for Hadon Universitair Medisch Centrum Proton Partners International Medical Radiology of FMBA Therapy) (UMGC) Newcastle Dimitrovgrad, Russia Caen, France Groningen, Netherlands Newcastle, UK Opening in 2018 Opening in 2017 Opening in 2018 Opening in 2018

Proteus®PLUS Proteus®ONE Proteus®PLUS Proteus®ONE • Gantry Treatment Rooms (2) • 2 Gantry Treatment Room (PBS Dedicated Nozzle) • incl. Cone Beam CT • Small Fixed Beam Treatment room (Eye Line) • Horizontal and Inclined BTR http://cluster-dgrad.ru/en/

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Proton Partners International Proton Partners International UNIVERSITAIR ZIEKENHUIS LEUVEN London Newport Leuven, Belgium London, UK Newport, UK Opening in 2018 Opening in 2018 Opening in 2018 Proteus®ONE Proteus®ONE Proteus®ONE • incl. Cone Beam CT • incl. Cone Beam CT • incl. Cone Beam CT

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Wanjie Proton Therapy Center Korean National Cancer Center Apollo Proton Therapy Center Japan Proteus®ONE Site 1 Zibo, China Ilsan, Korea Chennai, India Japan Treating since 2004 Treating since 2007 Opening in 2017 Opening in 2017

Proteus®PLUS Proteus®PLUS Proteus®PLUS Proteus®ONE • Gantry Treatment Room • Gantry Treatment Rooms (2) • Gantry Treatment Rooms (2) • Fixed-Beam Treatment Room • Fixed-Beam Treatment Room • Fixed-Beam Treatment Room http://www.wanjie.cn/lxwm/ http://www.nccproton.com/ https://www.apollohospitals.com

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Japan Proteus®ONE Site 2 Zhuozhou Proton Therapy Center Guangdong Heng Ju Medical CCH Taipei Proton Therapy Center Japan Hebei, China Technologies Co. Limited Taipei, Taiwan Opening in 2017 Opening in 2017 Guangzhou, China Opening in 2017&2018 Opening in 2018 Proteus®ONE Proteus®PLUS Proteus®ONE • Gantry Treatment Rooms (4) Proteus®PLUS • Fixed-Beam Treatment Room • Gantry Treatment Rooms (3) • Cone Beam CT

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TATA MEMORIAL CENTRE Qingdao Zhong Jia Lian He Mumbai, India Healthcare Management Co., Ltd. Opening in 2019 Qingdao, Shandong Province, China Opening in 2018 Proteus®PLUS • Gantry Treatment Rooms (3) Proteus®PLUS • Gantry Treatment Rooms (4) • Fixed-Beam Treatment Room • Cone Beam CT