Authors: Pallavi Subhraveti Ron Caspi Quang Ong Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Mbou1201294Cyc: Methanoculleus bourgensis MS2T Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari

RS09215 RS02310 RS01550 RS10455 RS00285 RS08495 RS12455 RS06215 RS07475 RS03140 RS05140 RS00970 RS02530 RS03710 RS01405 RS00610 RS04320 RS00050 RS07880 RS09465 RS00240 RS10585 RS01175 RS10720 RS05860 RS12440 RS10215 RS02315 RS11815 RS09725 RS11820 RS03540 RS01445 RS06130 RS05980 RS08175 RS08190 RS10050 RS03115 RS06200 RS02270 RS06000 RS12560 RS11985 RS06115 RS11385 RS00900 RS13550 RS05945 RS11645 RS01325 RS00600 RS02300 RS10700 RS09245 RS00635 RS10960 RS01995 RS11730 RS10705 RS01055 RS09125 RS01135 RS02645 RS13210 RS01940 RS02040 RS10715 RS11995 RS03775 RS00640 RS00030 RS13070 RS03955 RS05130 RS09140 RS09545 RS12705 RS02305 RS02695 RS08315 RS00095 RS03405 RS06955 RS12925 RS04830 RS11335 RS10620 RS11145 RS10990 RS08050 RS00790 RS05360 RS00190 RS11185 RS05675 RS12690 RS01820 RS11895 RS03535 RS03985 RS01050 RS04290 RS06980 RS06025 RS10070 RS06640 RS02280 RS07985 RS00630 RS03385 RS06195 RS04210 RS09375 RS06275 RS00215 RS05300 RS07190 RS00880 RS07485 RS02195 RS06500

RS00315 RS01120

RS11445 RS10860

RS05050 RS01270 biotin RS09770 biotin Nucleoside and Nucleotide Biosynthesis Glycolysis Amine and Polyamine α a [formate C (1S,2R)-1- a [protein]-L- 54 6-O-trans- 6-O- -mycolyl- α-D-Glc-(1->2)-α-D- + an electron- a pseudouridine (2R,3S)-3- a nucleoside + + Biosynthesis Nucleoside and Nucleotide Degradation a reduced + NADH H a nucleoside MoO - 5 [DNA] precorrin-6B H RS00835 H UMP biosynthesis I UMP biosynthesis III glycolysis I (from glucose 6-phosphate) SAM acetyltransferase]- Glu NAD a protein transfer quinone a ribonucleic acid 2 C-(indol-3- glutamate-O 3',5'-ADP sulfite methoxy-mycolyl- trehalose 6- isopropylmalate 5-MTR-1-P RS00305 UMP biosynthesis II superpathway of adenosine pyrimidine inosine-5'-phosphate biosynthesis II 5-aminoimidazole pyrimidine deoxyribonucleotide Aminoacyl-tRNA Charging flavodoxin Glc-(1->3)-α-D-Glc- triphosphate molybdopterin GTP ser in tRNA biotin ATP triphosphate dGDP XMP glycine NADH yl)glycerol -methyl-ester tRNA trehalose 6- DEAD/DEAH phosphate cobalt-precorrin- 3-isopropylmalate nucleoside nucleotides de novo biosynthesis I phosphorylation spermidine biosynthesis I ribonucleoside- glutamate synthase: proteasome endopeptidase (1->3)-α-D-Man- DNA-directed cofactor histidine kinase: phosphoadenosine bifunctional S-methyl-5- deoxyribonucleotides ribonucleotide biosynthesis I nucleoside and nucleotide degradation (archaea) dehydrogenase molybdenum cofactor phosphate box helicase: 7 (C(5))- dehydratase: ribonucleoside- GMP synthase: triphosphate BN140_RS07800 complex,subunit alpha: α 3-phosphate tryptophan (pseudouridine(54) phosphosulfate bifunctional bifunctional biotin- triphosphatase: thioribose-1- + + hydrogencarbonate gln hydrogencarbonate gln de novo biosynthesis IV tRNA charging D-glucopyranose 6-phosphate (1->2)- -D-Man- RNA polymerase: BN140_RS00735 alpha,alpha- diphosphate BN140_RS05350 H ATPase H gln AIR dTMP dCMP gln (quinone): guanylyltransferase: synthase -N(1))- BN140_RS04650 methyltransferase: BN140_RS08575 -[acetyl-CoA- BN140_RS00335 hydrogencarbonate CTP PRPP glutaminyl-tRNA reductase glutamate BN140_RS03855 (1->2)-α-D-Man- BN140_RS00910 reductase: alpha,alpha- trehalose- phosphate phosphoribosylaminoimidazole dTMP kinase: cytidylate kinase: SAM BN140_RS07660 BN140_RS04245 chemotaxis BN140_RS07940 BN140_RS08580 reductase, GMP synthase: IMP asp biosynthesis via activating protein: synthase (NADPH) proteasome endopeptidase (1->3)-[α-D-Man- BN140_RS00915 subunit alpha: methyltransferase BN140_RS11580 trehalose- type I restriction phosphate carboxylase] non-canonical isomerase: RS00300 carbamoyl carbamoyl non-canonical carboxylase: BN140_RS04000 amidophosphoribosyltransferase: BN140_RS03945 BN140_RS08510 glucose-6-phosphate adenosine guanosine response regulator adenosylcobalamin- BN140_RS02405 carbamoyl S-adenosylmethionine Secondary arginine-- BN140_RS06445 α NADH molybdopterin- BN140_RS07550 TrmY: phosphate enzyme: precorrin-6Y C5,15- 3-isopropylmalate synthetase/biotin purine NTP BN140_RS03780 H + RS10795 H + phosphate phosphate purine NTP BN140_RS00560 dTDP dCDP arg transamidation isomerase: , homotetrameric: complex, archaeal, beta (1->2)- -D-Man- a [protein]- BN140_RS00920 protein-glutamate phosphoadenosine synthase (UDP- dependent: phosphoribosylaminoimidazole β CMP decarboxylase: Metabolite tRNA ligase: uridine α dehydrogenase: [+ 2 isozymes] 1 BN140_RS01515 synthase (UDP- BN140_RS13420 operon repressor: GMP phosphate pyrophosphatase: 5-phospho- - BN140_RS02220 AmmeMemoRadiSam BN140_RS10075 subunit: BN140_RS09085 (1->3)-[ -D-Man- L-asparagine BN140_RS00925 guanine D-glyceraldehyde methylesterase: an N - phosphosulfate forming)/trehalose- methyltransferase dehydratase: pyrophosphatase: ribose 1,5- BN140_RS01340 synthase: synthase: adenylosuccinate carboxylase catalytic phosphorylation BN140_RS06880 Biosynthesis BN140_RS07210 Glu trp BN140_RS05490 BN140_RS09765 synthase: D-ribosylamine nucleoside- nucleoside- an L-arginyl- + (1->2)-α-D-Man- BN140_RS07680 BN140_RS00930 dinucleotide 54 forming)/trehalose- (decarboxylating) BN140_RS01575 BN140_RS07025 BN140_RS09605 BN140_RS09605 synthetase: BN140_RS07025 putrescine dAdoMet glucose-6-phosphate cytidine system radical H NADH 2-oxoglutarate gln a peptide a peptide 3-phosphate BN140_RS09405 methylpseudouridine reductase: a double stranded phosphatase: biotinyl-5'- bisphosphate subunit: BN140_RS07430 Arg an electron- + a nucleoside GDP BN140_RS09605 phosphoribosylamine- diphosphate diphosphate CMP myo-inositol [tRNA ] adenosine guanosine uridine (1->6)]-α-D-Man- NAD biosynthesis a [protein]-α- in tRNA phosphatase: BN140_RS07195 subunit CbiT: BN140_RS01580 adenylate BN140_RS09610 BN140_RS09610 BN140_RS00020 nucleoside Arg isomerase: SAM enzyme: [+ 7 isozymes] MeOH BN140_RS10890 DNA with 5'- isomerase: RS01115 CAIR kinase: kinase: a tRNA phosphorylase: phosphorylase: phosphorylase: β transfer quinol L-glutamate trehalose-BN140_RS07195 α α BN140_RS07905 (2S)-2- diphosphate RS01505 BN140_RS09610 -glycine ligase: cytidylate kinase: N-acetyltransferase: biosynthesis BN140_RS11540 (1->6)]- -D-Man- a ribonucleic acid protein B: PAPS terminal phosphate , '-trehalose BN140_RS08090 triphosphatase: BN140_RS03430 BN140_RS03430 an L-glutamyl- BN140_RS10435 AMP BN140_RS05395 BN140_RS05395 BN140_RS08310 a [formate C oligosaccharyl trans-methoxy- α isopropylmalate 5-(methylthio) carbamoyl asp carbamoyl asp adenylo-succinate BN140_RS09660 BN140_RS08510 BN140_RS11470 a flavodoxin (1->4)-β-D-GlcNAc- guanylylBN140_RS05580 6- -mycolate precorrin-8x carbamoyl asp BN140_RS00335 phosphoribosylaminoimidazolesuccinocarboxamide D-glucopyranose [tRNA Gln ] met 5'-deoxyadenosine acetyltransferase]- transferase, mono-mycolate ribulose 1- phosphate phosphate dTTP dCTP CDP UMP CMP semiquinone (1->4)-α-D-GlcNAc- molybdenum phosphate CDP synthase: BN140_RS02715 GAR spermidine 6-phosphate F6P α-D-ribose- glycin -2-yl radical Glc Man a dolichyl phosphate adenylosuccinate inositol-3- glutamyl-tRNA(Gln) diphosphodolichol3 9 archaeosortase A cofactor nucleoside- GlcNAc -[protein] diphosphate RS07015 lyase: ribonucleoside- phosphate AMP AMP 1-phosphate AMP 2 system-associated: aspartate aspartate SAICAR phosphoribosylglycinamide diphosphate amidotransferase: RS06185 aspartate BN140_RS11755 diphosphate pyrimidine deoxyribonucleotides synthase: cys 6-phosphofructokinase: phosphorylase: phosphorylase: phosphorylase: BN140_RS07090 carbamoyltransferase carbamoyltransferase formyltransferase: kinase: BN140_RS04560 fructose 1,6- carbamoyltransferase reductase, de novo biosynthesis I BN140_RS09525 BN140_RS10840 BN140_RS08310 BN140_RS08310 BN140_RS08310 regulatory subunit: regulatory subunit: adenylosuccinate BN140_RS01450 BN140_RS03430 an L-cysteinyl- BN140_RS04565 bisphosphatase: regulatory subunit: adenosylcobalamin- 6-phosphofructokinase: ω BN140_RS03800 BN140_RS03800 AMP lyase: BN140_RS11755 UDP CTP Ins(3)P Cys DNA combined with exogenous DNA a (2R)-2-hydroxy a 3-methyl- GDP-α-D- a 1-phosphatidyl- a 2-O-(6-O-acyl- -saturated 6-O-cis-methoxy- a negatively α,α-trehalose a double a [protein]- BN140_RS03800 CTP [tRNA ] aspartyl/glutamyl- BN140_RS06475 5-amino-6-(5-phospho- GDP-α-D- protoporphyrinogen IX a ribonucleoside 3-ethylmalate RS10060 dependent: ribonucleoside- non-canonical FGAR a tRNA Cys BN140_RS11170 α-D-ribose 1,5- even numbered branched 2,3,4- GDP-α-D- α-D-mannosyl)- C55 dolichol H O diphosphate mycolyl-trehalose (R)-NADPHX aspartate aspartate tRNA(Asn/Gln) D-ribitylamino)uracil to form a recombinational junction mannose 1D-myo-inositol mannose 5'-monophosphate 2 XMP IMP supercoiled DNA 6-phosphate stranded DNA L-tyrosine dADP IMP aspartate BN140_RS01340 AICAR myo-inositol-1(or 4)- bisphosphate diaminohydroxyphosphoribosylaminopyrimidine Holliday junction branch straight chain saturated fatty acid glycosyl mannose 1-phosphatidyl- phosphate flavodoxin: 6-phosphate DNA DNA 3-isopropylmalate TrkA domain bifunctional carbamoyltransferase: carbamoyltransferase: diphosphate purine NTP amidotransferase: AMP-dependent glycosyltransferase, bifunctional V-type H(+)- bifunctional bifunctional RS05075 carbamoyltransferase: adenylate kinase: phosphoribosylformylglycinamidine monophosphatase: reductase: BN140_RS01210 transferase family glycosyl 5'/3'-nucleotidase 5'/3'-nucleotidase dehydrogenase: protein: ribonucleoside- BN140_RS03805 BN140_RS03805 dCDP reductase, pyrophosphatase: DHAP β-D-fructose 1,6-bisphosphate Carbohydrate Degradation migration DNA helicase 2,3,4-saturatedAMP-dependent synthetase: 1D-myo-inositol TIGR04182 family: BN140_RS02845 metallophosphatase/ translocating topoisomerase VI: alpha,alpha- topoisomerase ADP-dependent IMP BN140_RS08500 bifunctional synthase: BN140_RS02710 pyrimidine BN140_RS11625 ribose 1,5- SurE: BN140_RS06600 alpha,alpha- SurE: BN140_RS06600 diphosphate BN140_RS03805 adenosylcobalamin- BN140_RS07025 BN140_RS09490 5-amino-6-(5- RuvB: BN140_RS10295 fatty acid BN140_RS10470 1: BN140_RS08930 transferase family BN140_RS09705 protoporphyrinogen pyrophosphatase: BN140_RS04015 trehalose- VI subunit B: BN140_RS08565 BN140_RS06985 NAD(P)H-hydrate dehydrogenase: phosphoribosylaminoimidazolecarboxamide ribonucleosides salvage I BN140_RS11630 bisphosphate synthetase: 5'-nucleotidase: trehalose- RS01385 nucleoside- dependent: [+ 2 isozymes] [+ 2 isozymes] 1: BN140_RS08930 oxidase: bifunctional bifunctional BN140_RS04020 BN140_RS04015 TrkA domain- dehydratase/ reductase, nucleoside BN140_RS11635 fructose-bisphosphate isomerase: phosphoribosylamino) crossover junction BN140_RS10470 [+ 3 isozymes] a 2-O-(α-D- β-D-mannosyl-[+ 2 isozymes] BN140_RS02145 BN140_RS01125 phosphate phosphate 3-isopropylmalate BN140_RS03930 N-carbamoyl- N-carbamoyl- diphosphate kinase: formyltransferase/inosine monophosphate cytidine myo-inositol gln D-mannose degradation a (R)-2-hydroxy a 3-methyl- a 2-O-(6-O-acyl-[+ 2 isozymes] metallophosphatase/ metallophosphatase/ adenosylcobalamin- N-carbamoyl- ADP BN140_RS01340 triphosphatase: triose-phosphate aldolase: BN140_RS10135 uracil reductase: endodeoxyribonuclease mannosyl)-1- (C55 ω-saturated BN140_RS09975 pyrophosphatase: synthase (UDP- DNA synthase (UDP- DNA gyrase: dehydrogenase: containing protein: NAD(P)H-hydrate L-aspartate L-aspartate BN140_RS03430 cyclohydrolase: BN140_RS11355 FGAM an L-glutaminyl- BN140_RS07270 [+ even3 isozymes] numbered branched α-D-mannosyl) 5'/3'-nucleotidase dependent: L-aspartate dUDP BN140_RS00335 isomerase: [+ 2 isozymes] BN140_RS05930 RuvC: BN140_RS10305 diphosphate AMP GDP GDP protoporphyrin IX 5'-nucleotidase: 5'-nucleotidase: topoisomerase I: forming)/trehalose- BN140_RS05990 BN140_RS01585 BN140_RS07890 epimerase: XMP RS10105 Gln D-mannopyranose phosphatidyl- α dolichyl SurE: BN140_RS02265 forming)/trehalose- an L-glutaminyl- [tRNA ] ribose 1,5- 5-amino-6-(5-phospho- resolution of recombinational junction diphosphate AMP straight chain 2,3,4-saturated -6-O-( -D- BN140_RS02145 BN140_RS02145 a [protein]- BN140_RS01340 dCTP CDP BN140_RS10115 GDP + BN140_RS11620 phosphatase: BN140_RS05995 BN140_RS03830 dihydroorotase: dihydroorotase: FAICAR nucleoside- phosphoribosylformylglycinamidine [tRNA Gln ] 6-phosphate 2,3,4-saturated fatty acyl-CoA 1D-myo-inositol mannosyl)-1- phosphate) BN140_RS06600 phosphate H phosphatase: 2-oxovalerate L-tyrosine dihydroorotase: bisphosphate mannose-1-phosphate D-ribosylamino)uracil formation of two intact strands xanthosine inosine BN140_RS07195 a negatively ADP RS02500 BN140_RS11460 BN140_RS11460 ATP synthase ribonucleoside- diphosphate kinase: ribonucleoside- cyclo-ligase: BN140_RS00520 a tRNA Gln fatty acyl CoA phosphatidyl- a ribonucleoside trehalose- BN140_RS07195 a relaxed DNA phosphate (S)-NADPHX BN140_RS11460 bifunctional uridine CMP isomerase: guanylyltransferase/ supercoiled DNA subunit A: diphosphate BN140_RS03430 diphosphate 1D-myo-inositol cis-methoxy- α,α-trehalose phosphoribosylaminoimidazolecarboxamide AIR D-glyceraldehyde 3-phosphate BN140_RS08090 mannose-6- (S)-dihydroorotate (S)-dihydroorotate BN140_RS00850 reductase, uridine kinase: mono-mycolate (S)-dihydroorotate dUMP formyltransferase/inosine monophosphate dUTP reductase, D-ribulose-1,5- phosphate isomerase: RS07365 [+ 9 isozymes] adenosylcobalamin- adenosylcobalamin- BN140_RS01655 thymidylate cyclohydrolase: BN140_RS11355 adenine salvage type I glyceraldehyde-3- UTP and CTP dephosphorylation I bisphosphate BN140_RS05555 RS12755 dihydroorotate dihydroorotate dihydroorotate dependent: dependent: UMP glutamate-- phosphate dehydrogenase: F6P an odd numbered 1518 6-O-trans-keto- dehydrogenase dehydrogenase synthase: Glu ribulose- a polycistronic (2E,6E)-farnesyl GDP-α-D- a dolichyl an [eIF5A- adenine / a ribonucleoside α a monocarboxylic 3-[(4'-methylthio) (2R,3S)-3- geranylgeranyl a double CTP dehydrogenase: BN140_RS01340 BN140_RS01340 tRNA ligase: stearate spermidine an unsulfurated an -limit dextrin (S)-NADPHX electron electron BN140_RS08265 BN140_RS10810 UTP bisphosphate straight chain IPP mannose precursor]-lysine adenine 1519 in 16S rRNA cys mycolyl-trehalose acid amide butyl]malate a malonyl-[acp] isopropylmalate chlorophyll a stranded DNA dIDP BN140_RS04265 ATP IMP dUMP tRNA precursor diphosphate phosphate [sulfur carrier] diphosphate 4-alpha- AMP deoxycytidine dCDP adenine BN140_RS02855 an L-glutamyl- glyceraldehyde-3- carboxylase tRNA-intron 2,3,4-saturated di-trans,poly-cis- dolichyl-phosphate beta- AMP-dependent deoxyhypusine 16S rRNA cysteine ribonucleoside- 6-phosphate aspartyl/ 3-isopropylmalate 3-isopropylmalate geranylgeranyl type I restriction bifunctional transfer subunit: transfer subunit: PRPP dTMP bifunctional triphosphate RS03005 UTP and CTP de thymidylate guanosine Glu fatty acidAMP-dependent synthetase: synthase: (adenine(1518)-N(6)/ glucanotransferase: 5'/3'-nucleotidase glutamyl-tRNA dehydrogenase: SAM-dependent dehydrogenase: reductase: endonuclease ADP-dependent nucleoside- BN140_RS04260 BN140_RS04260 orotate nucleoside- [tRNA ] phosphate dehydrogenase: CTP synthetase: large subunit: endonuclease: decaprenylcistransferase: D-mannosyltransferase: desulfurase NifS: diphosphate alpha,alpha- RS08865 dADP synthase: deoxyribonucleotides glu synthetase: BN140_RS10975 SurE: BN140_RS06600 methyltransferase: deaminase: diphosphate PRPP PRPP dTMP kinase: novo biosynthesis a tRNA BN140_RS12985 BN140_RS02410 BN140_RS10770 BN140_RS08545 BN140_RS03020 BN140_RS05800 BN140_RS10470 BN140_RS12335 adenine(1519)-N(6))- BN140_RS12625 reductase, amidotransferase BN140_RS08565 BN140_RS08565 BN140_RS01090 subunit R: NAD(P)H-hydrate orotate orotate diphosphate kinase: a tRNA intron trehalose- BN140_RS00115 BN140_RS08345 kinase: BN140_RS03945 BN140_RS08265 de novo biosynthesis I adenine adenine deaminase: a 5'-half-tRNA BN140_RS10470 [+ 3 isozymes] deoxyhypusine dimethyltransferase: adenosylcobalamin- 4-alpha- bifunctional subunit A: 3-isopropylmalate 3-isopropylmalate geranylgeranyl BN140_RS09305 dehydratase/ orotate UMP BN140_RS03430 UMP 3-phospho- Amino Acid Degradation with a 2',3'-cyclic a 3'-half-tRNA an odd numbered di-trans,poly-cis- [+ 2 isozymes] [+ 3 isozymes] phosphate a double nucleoside- phosphoribosyltransferase: BN140_RS06330 CTP molecule with [+ 3 isozymes] a dolichyl β- BN140_RS01540 a sulfurated glucanotransferase: metallophosphatase/ BN140_RS11630 a malonyl-[acp] NAD(P)H-hydrate deoxycytidine BN140_RS03430 phosphoribosyltransferase- dTDP uridylate kinase: dTMP 13-DPG D-glycerate phosphate and molecule with decaprenylcistransferase: synthase: N 6 -dimethyladenine 1518 dependent: synthase (UDP- dehydrogenase: dehydrogenase: reductase: stranded DNA orotate orotate diphosphate kinase: dCTP GDP 5'/3'-nucleotidase straight chain diphosphate AMP stearoyl-CoA ala triphosphate BN140_RS02675 a 2',3'-cyclic diphosphate AMP GDP D-mannosyl 6 1519 [sulfur carrier] BN140_RS11290 5'-nucleotidase: methyl ester epimerase: dITP like protein: BN140_RS00755 BN140_RS02550 a 5'-hydroxyl a 5'-OH end 2,3,4-saturated BN140_RS03025 BN140_RS02950 /N -dimethyladenine BN140_RS01340 forming)/trehalose- a monocarboxylate BN140_RS01585 BN140_RS01585 BN140_RS05955 with 5'-terminal RS05740 RS04835 phosphoribosyltransferase- phosphoribosyltransferase- BN140_RS03430 nucleoside- dTMP kinase: SurE: L-arginine degradation V di-trans,octa-cis an [eIF5A- a 2'- a α-limit dextrin BN140_RS02145 7-(methylthio)-2- 4-methyl-2- deaminase: orotate ribonucleoside- isoleucine-- phosphate end phosphate propane- phosphatase: chlorophyll a BN140_RS03830 like protein: BN140_RS00755 like protein: BN140_RS00755 diphosphate kinase: [+ 4 isozymes] BN140_RS03945 ile phosphoglycerate BN140_RS06600 (arginine deiminase pathway) terminus fatty acyl CoA -undecaprenyl precursor]- in 16S rRNA deoxyribonucleoside with short branches oxoheptanoate oxopentanoate phosphate BN140_RS11605 diphosphate hypoxanthine 1,3-diamine adenosine BN140_RS07195 NADPH phosphoribosyltransferase: BN140_RS03430 UDP tRNA ligase: kinase: BN140_RS00865 CMP diphosphate deoxyhypusine 5'-diphosphate trehalose- orotate orotate dATP dTDP reductase, AMP bifunctional UTP BN140_RS09665 BN140_RS01005 an L-isoleucyl- phosphoglycerate trans-keto- phosphoribosyltransferase: phosphoribosyltransferase: dTTP nucleoside- adenosylcobalamin- 5'/3'-nucleotidase metallophosphatase/ arg nucleoside- hypoxanthine [tRNA Ile ] RS09210 BN140_RS09665 BN140_RS09665 diphosphate dependent: kinase: BN140_RS10835 mono-mycolate diphosphate kinase: phosphoribosyltransferase: a tRNA Ile SurE: 5'-nucleotidase: RS12280 orotidine 5'- kinase: BN140_RS03430 BN140_RS01340 BN140_RS02675 BN140_RS06600 BN140_RS02145 amidinotransferase: phosphate BN140_RS03430 3-phospho-D-glycerate orotidine 5'- orotidine 5'- dGDP (7,8-dihydropterin- a 2-O-(α-D- a (1->4)- 6-O-cis-keto- a 3- 3-[(3'-methylthio) (3R,5S)-3- dCTP dTTP bifunctional uridine BN140_RS00620 16-hydroxypalmitate a CDP- sn-glycerol laurate uroporphyrinogen-III a 3-oxopimeloyl- a membrane propionamide pyridoxine phosphate phosphate orotidine-5'- UTP 6-yl)methyl 4-aminobenzoate isovalerate GDP-α-D- mannosyl)-1- 3'-dephospho- α-D-glucan oxidized mycolyl-trehalose oxododecanoyl- hydroxy-1- IMP metallophosphatase/ diacylglycerol 3-phosphate ATP ATP GMP propyl]malate [acp] methyl ester compartment 5'-phosphate deoxycytidine IDP RS03040 phosphate nucleoside- AMP-dependent diphosphate acetyl-coenzyme AMP-dependent mannose phosphatidyl- CoA alpha-glucan uroporphyrin-III C- coenzyme F -2 6-phosphate [acp] 3-isopropylmalate pyrroline-5- aspartyl/ pyridoxamine phosphoglycerate phosphoglyceromutase: 5'-nucleotidase: L-citrulline CDP-diacylglycerol-- dihydropteroate 420 cell division control orotidine-5'- orotidine-5'- CTP synthetase: leucine-- A synthetase: synthetase: glycosyl triphosphoribosyl- phosphorylase: methyltransferase: 5'/3'-nucleotidase bifunctional short-chain dehydrogenase: short-chain triphosphate nucleoside- RS13075 decarboxylase: diphosphate kinase: leu mutase: BN140_RS01760 gpmA synthetase: glycerol-3-phosphate 3- synthase: 1D-myo-inositol coenzyme F390 protein Cdc6: carboxylatepyrroline-5- glutamyl-tRNA 5'-phosphate phosphate phosphate BN140_RS02410 tRNA ligase: BN140_RS02145 transferase family dephospho- BN140_RS10790 SurE: BN140_RS06600 alpha,alpha- dehydrogenase: dehydrogenase: deaminase: diphosphate BN140_RS12340 BN140_RS03430 BN140_RS10470 phosphatidyltransferase: BN140_RS00165 BN140_RS10470 BN140_RS09580 synthetase: BN140_RS08565 BN140_RS00005 carboxylate amidotransferase oxidase: [+ 3 isozymes] [+ 3 isozymes] BN140_RS02735 trehalose- BN140_RS10875 BN140_RS08345 decarboxylase: decarboxylase: CTP BN140_RS01295 an L-leucyl- cytidine [+ 3 isozymes] [+ 4 isozymes] [+ 3 isozymes] 1: BN140_RS08930 CoA synthase: [+ 2 isozymes] uroporphyrinogen III BN140_RS11830 bifunctional BN140_RS10875 3-isopropylmalate reductase: subunit A: BN140_RS00715 kinase: ornithine BN140_RS02385 dihydropteroate α α phosphate a (3R)-3- a (3R)-3- [+ 3 isozymes] BN140_RS12340 BN140_RS12340 UMP dGTP [tRNA Leu ] 1-(3-sn- a 2,6-di-O-([+ 2 isozymes]- 2'-(5''-triphospho-BN140_RS03625 -D- metallophosphatase/ deoxycytidine BN140_RS03430 RS00135 carbamoyltransferase: 16-hydroxypalmitoyl- a (1->4)- methyltransferase: [+ 3 isozymes] hydroxydodecanoyl- dehydrogenase: hydroxypimeloyl- a membrane BN140_RS10180 BN140_RS11630 [+ 4 isozymes] a tRNA Leu 2-phospho-D-glycerate phosphatidyl) synthase: D-mannosyl)-1- α glucopyranose synthase (UDP- trans-4-hydroxy- UMP UMP AMP diphosphate CMP isovaleryl-CoA AMP diphosphate AMP diphosphate lauroyl-CoA GDP adenine -D-ribosyl)-3'- α-D-glucan BN140_RS08215 coenzyme F -A 5'-nucleotidase: BN140_RS01585 compartment triphosphate ITP BN140_RS09655 CoA -sn-glycerol BN140_RS11910 phosphatidyl- 1-phosphate 390 forming)/trehalose- [acp] [acp] methyl ester L-proline propanoate PLP RS09425 Carbohydrate Biosynthesis 7,8- dephospho-CoA BN140_RS02145 6-(methylthio)- deaminase: 3-phosphate 1D-myo-inositol precorrin-2 phosphatase: phosphopyruvate pyrimidine deoxyribonucleosides degradation dihydropteroate guanosine 2-oxohexanoate BN140_RS11605 carbamoyl BN140_RS07195 gluconeogenesis II (Methanobacterium thermoautotrophicum) trehalose biosynthesis VI hydratase: BN140_RS02895 L-ornithine trehalose-cis-keto- dUTP RS01910 UDP-α-D-galactose GDP-mannose biosynthesis 2'-deoxycytidine phosphate mono-mycolate biosynthesis α val Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis CO an NDP- - valine--tRNA ligase: carbamate kinase: RS01110 2 D-glucopyranose D-glucopyranose D-glucose phosphoenolpyruvate BN140_RS00625 UDP-α-D-glucose 6-phosphate BN140_RS03950 an L-valyl- glycosyl glucose-6- CoB-CoM dolichyl a [protein]- D-ribulose 3-[(6'-methylthio) a (3R,5Z)-3- dCDP a double- formylmethanofuran Val 2+ a [ThiI sulfur-carrier pyridoxamine RS08810 cob(II)yrinate a,c-diamide nucleoside- transferase family [tRNA ] dihydromethanophenazine PRPP quinolinate palmitate protoporphyrin IX Mg oleate cys glycerophosphoserine a protein NaMN NMN a 3-oxoglutaryl- (S)-NADHX arg [2Fe-2S] iron-sulfur cluster biosynthesis factor 430 biosynthesis coenzyme A biosynthesis I (prokaryotic) geranyl diphosphate coenzyme M trans, trans-farnesyl phosphate Val 2'-deoxyuridine thymidine CO heterodisulfide diphosphooligosaccharide L-asparagine 5-phosphate an acetoacetyl-[acp] hexyl]malate hydroxy-tetradec- helix DNA biosynthesis II (late adenosylcobalamin salvage from cobinamide II factor 420 biosynthesis dehydrogenase a tRNA phosphoenolpyruvate 2 protein]-L-cysteine [acp] methyl ester ribonucleoside- 5'-phosphate biosynthesis II diphosphate biosynthesis diphosphate- 1: BN140_RS01225 isomerase: CoB--CoM oligosaccharyl nicotinate-nucleotide AMP-dependent protoporphyrin IX AMP-dependent cysteine glycerophosphoryl 3,4-dihydroxy- endopeptidase La: bifunctional bifunctional 3-isopropylmalate 5-enoyl-[acp] DNA helicase pyridoxamine bifunctional biosynthesis subunit E: synthase: BN140_RS02665 short-chain short-chain short-chain diphosphate pyruvoyl- cobalt incorporation) sugar epimerase: [+ 2 isozymes] pyruvate kinase: AMP L-methionine degradation heterodisulfide transferase, pyrophosphorylase: synthetase: magnesium chelatase: synthetase: diester 2-butanone- metallophosphatase/ metallophosphatase/ dehydrogenase: RecQ: 5'-phosphate ADP-dependent (R)-4'- BN140_RS11690 BN140_RS02220 uracil desulfurase NifS: BN140_RS00230 reductase, dependent RS03740 uroporphyrinogen-III cobinamide 3-phospho- BN140_RS01195 α,α-trehalose phosphoenolpyruvate BN140_RS12160 phosphorylase: archaeosortase A BN140_RS04390 BN140_RS10470 BN140_RS01100 BN140_RS10470 phosphodiesterase: 4-phosphate 5'-nucleotidase: dehydrogenase: BN140_RS08565 dehydrogenase: dehydrogenase: BN140_RS03320 uroporphyrinogen-III L-cysteine desulfurase phosphopantothenate ARP IPP phosphorylase: I (to L-homocysteine) reductase subunit BN140_RS12625 peptidase: 5'-nucleotidase: oxidase: NAD(P)H-hydrate arginine uroporphyrinogen III phosphopantothenoylcysteine IPP [+ 14 isozymes] glucose-6- synthase: BN140_RS10800 BN140_RS08310 BN140_RS11130 BN140_RS02145 BN140_RS10875 BN140_RS10875 BN140_RS10875 adenosylcobalamin- RS02190 uroporphyrinogen III L-serine α [+ 2 isozymes] B: BN140_RS08630 system-associated: nicotinate [+ 3 isozymes] magnesium chelatase: [+ 3 isozymes] [+ 3 isozymes] synthase: BN140_RS04745 BN140_RS02145 3-isopropylmalate [+ 3 isozymes] BN140_RS00715 dehydratase/ methyltransferase: prenyltransferase: cob(I)alamin type 2 isopentenyl- UDP- -D- phosphate BN140_RS08310 a [ThiI sulfur- a (3R)-3- a (3R)-3- a (5Z)-3-oxo- dependent: an unwound decarboxylase: methyltransferase: cysteine (R)-4'- decarboxylase: BN140_RS05020 5-amino-6-(D- cysteate synthase: alanine-- [+ 4 isozymes] BN140_RS07090 phosphoribosyltransferase: BN140_RS11750 sn-glycerol BN140_RS12375 5'/3'-nucleotidase dehydrogenase: NAD(P)H-hydrate diphosphate THMPT a formylmethanofuran galactose isomerase: ala thymine met a [glycoprotein]- ala carrier protein]-S- ser 1-deoxy-L- a peptide a peptide 5'/3'-nucleotidase hydroxybutanoyl- hydroxyglutaryl- tetradec-5- BN140_RS01340 double- [+ 4 isozymes] BN140_RS06745 desulfurase NifS: BN140_RS08215 BN140_RS12545 adenolsyltransferase/ ribitylamino)uracil- BN140_RS00275 tRNA ligase: a dolichyl AMP diphosphate palmitoyl-CoA diphosphate AMP oleoyl-CoA 3-phosphate BN140_RS08215 phosphopantothenoyl- Delta-isomerase: pyruvate S-adenosylmethionine methanophenazine coenzyme M coenzyme B BN140_RS05400 Mg-protoporphyrin SurE: SurE: BN140_RS01585 epimerase: Mg 2+ 2+ geranyl cobinamide L-cysteate BN140_RS10435 L-asparagine- sulfanyl-L-cysteine glycero-tetrulose formate [acp] [acp] methyl ester enoyl-[acp] CDP stranded DNA PLP agmatine RS11195 Mg BN140_RS02350 [+ 2 isozymes] L-cysteine -L-tyrosine 4- BN140_RS09230 an L-alanyl- diphosphate BN140_RS06600 BN140_RS06600 9-(methylthio)- BN140_RS03830 [+ 2 isozymes] diphosphate ATP-dependent BN140_RS02870 formylmethanofuran-- F6P synthetase: [oligosaccharide] NaMN 4-phosphate β precorrin-1 methylphenol Ala β-D- 1-( -D 2-oxononanoate RS02520 precorrin-1 [+ 3 isozymes] phosphopantothenoylcysteine aspartate DMAPP tetrahydromethanopterin [tRNA ] BN140_RS04470 NADH adenolsyltransferase: transferase: a tRNA Ala 2-deoxy-α- ribosylnicotinate ribofuranosyl) decarboxylase: BN140_RS05020 aminotransferase: N-formyltransferase: PRPP biosynthesis I mannose-1-phosphate uracil SAM Mg 2+ RS06425 Mg 2+ uroporphyrinogen III an S-sulfanyl-[L- uroporphyrinogen III BN140_RS09940 BN140_RS07390 D-ribose 1- nicotinamide cysteine desulfurase] methyltransferase: BN140_RS04615 prenyltransferase: BN140_RS08610 guanylyltransferase/ Macromolecule Modification methyltransferase: 4'-phosphopantetheine 5-amino-5-(4- D-ribose 5- mannose-6- phosphate BN140_RS08215 adenosylcobinamide [+ 3 isozymes] BN140_RS12545 5-formyl- S-methyl-5'- BN140_RS08215 hydroxybenzyl)- phosphate phosphate isomerase: a 5,10- D-ribulose-1,5- (25S)-3- a 3,5,7,9,11,13,15- a [lipoyl-carrier a 3- 3-[(7'-methylthio) UDP a (5Z)-3- Mg 2+ RS01095 Mg 2+ RS10610 uroporphyrin-III C- (S)-lactate tetrahydromethanopterin ribose-phosphate archaeosine biosynthesis I thioadenosine UDP-α-D-glucose D-glucopyranose 6-phosphate 18-hydroxystearate decanoate a glycogen maltoheptaose (R)-pantoate 6 a 3-oxoicosanoyl- a 3-oxooctanoyl- pyrazinamide uroporphyrin-III C- phosphopantetheine hypothetical 6-(D-ribitylimino) 3-sulfopyruvate geranyl bisphosphate oxocholest- coenzyme A hepta-oxo- protein]-N -[(R) oxodocosanoyl- heptyl]malate oxododec- GGPP asp diphosphokinase: BN140_RS05555 methylenetetrahydrofolate GTP H O [acp] [acp] ribonucleoside- methyltransferase: adenylyltransferase: methenyltetrahydromethanopterin asn degradation II alpha-glucan alpha-glucan 2 2-dehydropantoate 3-isopropylmalate methyltransferase: protein: -5,6-dihydrouracil diphosphate D-mannopyranose bifunctional alpha,alpha- AMP-dependent bifunctional AMP-dependent ribulose- 4-en-26-oate acyl-CoA hexadecanoyl-[PKS-acp] -dihydrolipoyl]- [acp] 5-enoyl-[acp] aspartyl/ geranylgeranyl asparagine an S-sulfanyl-[cysteine BN140_RS09580 BN140_RS00770 S-methyl-5'- SAH elongation aldo/keto short-chain short-chain short-chain diphosphate short-chain BN140_RS09580 BN140_RS03795 BN140_RS12350 7,8-didemethyl- sulfopyruvate prenyltransferase: cyclohydrolase: BN140_RS00695 preQ trehalose-phosphate synthetase: methylenetetrahydrofolate synthetase: bisphosphate phosphorylase: phosphorylase: synthetase: 2-reductase: L-lysine pyridine nucleotide- dehydrogenase: glutamyl-tRNA reductase: synthase: desulfurase]-[disordered- PRPP gluconeogenesis I 6-phosphate an L-asparaginyl- 0 thioadenosine reductase, 3'-dephospho- 8-hydroxy-5- decarboxylase: methenyltetrahydromethanopterin 7-cyano-7- methylthioadenosine synthase (UDP-forming)/ BN140_RS10470 BN140_RS10470 carboxylase BN140_RS10790 BN140_RS12885 factor 1-alpha: reductase: BN140_RS04240 dehydrogenase: BN140_RS08565 dehydrogenase: dehydrogenase: dehydrogenase: amidotransferase RS01310 form scaffold precorrin-2 (R)-1-amino- BN140_RS12545 Asn dehydrogenase/ BN140_RS04930 disulfide BN140_RS01090 BN140_RS11640 RS03960 precorrin-2 (2S)-2- BN140_RS00280 Fis family [tRNA ] adenosylhomocysteinase: BN140_RS05310 BN140_RS08180 BN140_RS10875 BN140_RS10875 BN140_RS10875 adenosylcobalamin- BN140_RS10875 CoA deazariboflavin cyclohydrolase: BN140_RS08890 Asn deazaguanine tRNA- phosphorylase: trehalose-phosphatase: large subunit: [+ 2 isozymes] [+ 2 isozymes] 2-dehydropantoate 3-isopropylmalate subunit A: protein] complex 2-propanol O adenosylcobyrate farnesyltranstransferase: transcriptional tRNA [+ 3 isozymes] methenyltetrahydrofolate [+ 3 isozymes] α α (25S)-3- [+ 2 isozymes] 9-hydroxy-3,5,7,11,13,15- oxidoreductase: a (3R)-3- a (3R)-3- a (3R)-3- dependent: a (3R,5Z)-3- geranylgeranyl [+ 2 isozymes] cysteine phospholactate synthase (S)-malate BN140_RS05395 BN140_RS08820 BN140_RS07195 BN140_RS10770 -D- -D- [+ 3 isozymes] a [lipoyl-carrier siroheme synthase: dephospho- -2-phosphate BN140_RS02860 ribosyltransferase: cyclohydrolase: 2-reductase: BN140_RS02260 dehydrogenase: BN140_RS11630 reductase: precorrin-2 C(20)- sulfoacetaldehyde 5,10-methenyltetrahydromethanopterin regulator: 18-hydroxystearoyl- glucopyranose an α-limit dextrin glucopyranose maltohexaose oxocholest-4- hexaoxohexadecanoyl- 6 hydroxydocosanoyl- hydroxyicosanoyl- hydroxyoctanoyl- BN140_RS01340 hydroxydodec- asn desulfurase NifS: CoA kinase: 2-phospho-L-lactate subunit CofH: BN140_RS03820 5-MTR-1-P α α AMP diphosphate BN140_RS02740 diphosphate AMP decanoyl-CoA 3-phospho- phosphate GDP H + BN140_RS12485 protein]-N - BN140_RS01585 pyrazine-2- methyltransferase: BN140_RS09555 cobalamin (2E,6E)-farnesyl BN140_RS12630 UDP , -trehalose 6-phosphate CoA 2-phosphoglycolate 1-phosphate 1-phosphate en-26-oyl-CoA [PKS-acp] [acp] [acp] [acp] 5-enoyl-[acp] BN140_RS05955 BN140_RS02350 BN140_RS06440 guanylyltransferase: BN140_RS01140 L-homocysteine a 5,10- D-glycerate lipoyl-L-lysine 10-(methylthio)- dUDP carboxylate phytyl BN140_RS07910 biosynthesis diphosphate α tRNA-guanine(15) 2-dehydropantoate RS00810 RS02285 BN140_RS02725 -D-mannose methenyltetrahydrofolate 2-oxodecanoate diphosphate [+ 3 isozymes] sirohydrochlorin protein CobD: [+ 2 isozymes] transglycosylase: L-glutamine a [cysteine desulfurase]- coenzyme A (2S)-lactyl-2- 7,8-didemethyl- malate 1-phosphate aspartate-- precorrin-3A BN140_RS00035 2-(sulfomethyl) asp preQ BN140_RS10095at degradation II S-sulfanyl-[disordered- sirohydrochlorin diphospho- 8-hydroxy-5- a reduced 5,10-methylene- dehydrogenase: pyruvate tRNA(Asn) ligase: 0 adenosyl- thiazolidine- mannose-1- position 15 of form scaffold nickelchelatase: 5'-guanosine deazariboflavin factor 420 tetrahydromethanopterin BN140_RS04270 BN140_RS06750 a reduced a linear malto- β-D-fructofuranose an [RNA]-3'- UDP-4-amino-4-deoxy- a 3- a (9Z)-3- a (9Z)-3- cobinamide phosphate an L-aspartyl- C1 Compound Utilization (15Z)- a 5,10- 3-[(5'-methylthio) protein] complex 4-carboxylate an archaeal tRNA linoleate + + maltopentaose an adenine in DNA a 3-oxohexanoyl- a O- L-threonine 3- BN140_RS03615 [tRNA asp ] L-aspartate gln L-homocysteine a 5-methyltetrahydrofolate ferredoxin [iron- NADP H oligosaccharide SAH 1-phosphate ribonucleoside- β-L-arabinopyranose oxodocosanoyl- pentyl]malate oxohexadec- oxooctacos- a protein RS01730 cysteine phosphate 5,10-methylenetetrahydromethanopterin phosphoenolpyruvate guanyltransferase: archaeosine and Assimilation tetracosenoate methenyltetrahydrofolate [acp] sialoglycoprotein GDP ATP RS10765 asp hypothetical AMP-dependent AMP-dependent alpha-glucan alpha-glucan fructose- 3'-phosphate aminotransferase 3-isopropylmalate O-phosphate 5,6-dimethylbenzimidazole NaMN 2-phospho-L- reductase: BN140_RS08360 BN140_RS01370 tRNA degradation I methionine synthase: bifunctional sulfur] cluster ferredoxin- restriction [acp] 9-enoyl-[acp] 9-enoyl-[acp] desulfurase NifS: Ni-sirohydrochlorin 5-deoxyadenosylcobinamide synthase: synthase: protein: synthetase: phosphorylase: phosphorylase: S-adenosylhomocysteine bisphosphate RNA 3'-terminal- DegT: short-chain dehydrogenase: short-chain short-chain serine/threonine short-chain L-threonine-O- nucleoside- thiol reductase precorrin-3B lactate transferase: CO incomplete BN140_RS06755 synthetase: methylenetetrahydrofolate NADP+ reductase endonuclease BN140_RS02350 phosphate 2 BN140_RS02665 mannose-1-phosphate BN140_RS10090 deaminase: phosphate cyclase: dehydrogenase: dehydrogenase: dehydrogenase: protein kinase: dehydrogenase: 3-phosphate diphosphate thioredoxin: BN140_RS06725 5 oxaloacetate BN140_RS07805 BN140_RS10470 dehydrogenase/ BN140_RS10470 BN140_RS10790 BN140_RS12885 aldolase: BN140_RS10315 subunit M: BN140_RS08565 Ni-sirohydrochlorin nucleotidyltransferase: N -methyltetrahydromethanopterin guanylyltransferase/ archaeosine at reductive TCA cycle asp cobalamin-binding subunit alpha: precorrin-3B C(17)- [+ 3 isozymes] adenosylcobalamin biosynthesis from cobyrinate a,c-diamide I sulfoethylcysteine acetyl-CoA phosphoenolpyruvate [+ 2 isozymes] [+ 2 isozymes] BN140_RS05390 BN140_RS10135 BN140_RS00765 aminotransferase BN140_RS01705 BN140_RS10875 BN140_RS10875 BN140_RS10875 BN140_RS07030 BN140_RS10875 decarboxylase: kinase: BN140_RS00570 an S-sulfanyl-[cysteine a,c-diamide 2-phospho-L- position 15 of [+ 2 isozymes] protein: BN140_RS06070 [+ 3 isozymes] methenyltetrahydrofolate [+ 3 isozymes] BN140_RS10080 α α an [RNA]-3'- a (3R)-3- 3-isopropylmalate a (3R)-3- a (3R,9Z)-3- a cis-delta9-3- RS01590 methyltransferase: BN140_RS11060 synthase: synthase: mannose-6- aspartate an oxidized -D- -D- S-Inosyl-L- (R)-1-amino-BN140_RS11055 BN140_RS03430 predicted desulfurase]-S- synthase: lactate transferase: an archaeal tRNA acetyl-CoA Glu cyclohydrolase: a linear malto- [+ 2 isozymes] ribonucleoside-2',3'- DegT: [+ 3 isozymes] dehydrogenase: cob(II)yrinate α-ribazole phosphate isomerase: tyrosine-- aminotransferase: a tetrahydrofolate met (Z)-15- NADPH ferredoxin [iron- glucopyranose glucopyranose maltotetraose 6 hydroxydocosanoyl- hydroxyhexanoyl- hydroxyhexadec- a peptide hydroxyC28:1- a protein BN140_RS07925 adenosylcobinamide- BN140_RS11780 BN140_RS10800 tyr AMP diphosphate AMP diphosphate linoleoyl-CoA homocysteine an N -methyladenine 2-propanol O ADP GTP 2+ ABC 2+ sulfanyl-[disordered- BN140_RS03600 BN140_RS06730 pyruvate ferredoxin tetracosenoyl-CoA BN140_RS02740 oligosaccharide D-glyceraldehyde DHAP cyclophosphate BN140_RS10400 [acp] BN140_RS01585 [acp] 9-enoyl-[acp] [acp] Mo Mo a,c-diamide GDP 5'-phosphate BN140_RS05555 tRNA ligase: BN140_RS04615 10 sulfur] cluster 1-phosphate 1-phosphate UDP-β-L-threo- -2-phosphate transporter form scaffold [+ 2 isozymes] oxidoreductase: an N - in DNA 8-(methylthio)- precorrin-4 Ni-sirohydrochlorin a [methyl-Co(III) GDP-α-D- BN140_RS12990 an L-tyrosyl- [+ 3 isozymes] pentapyranos-4-ulose of Mo2+ protein] complex oxidized phosphoenol BN140_RS01185 formyltetrahydrofolate 2-oxooctanoate cysteine a,c-diamide CO corrinoid mannose Tyr oxaloacetate RS00090 adenosylcobinamide- coenzyme M pyruvate [tRNA ] 6 37 2+ 2+ cobalt-precorrin- coenzyme F -0 Fe-S protein] Tyr N -L-threonylcarbamoyladenosine [+ 7 isozymes] Mo RS02510 Mo desulfurase NifS: 420 a tRNA 4 C(11)- Ni-sirohydrochlorin GDP phosphopyruvate -modified tRNA biosynthesis L-lysine cob(I)yrinate pyruvate a long-linear α ω an [amino group carrier protein]- 2-(2-carboxy-4- an [amino group carrier 38- a DNA containing UDP-N-acetyl- a (7Z)-3-oxo- a (9Z)-3-oxo- an (11Z)-3- BN140_RS02350 a,c-diamide ribazoletransferase: 3-methyl-2- α , -9Z- a glycogen a uridine L(or D)-O- an oxidized methyltransferase: a,c-diamide bifunctional hydratase: degradation I 18-hydroxyoleate α -D-glucopyranose C-terminal-γ-(L-glutamate 5- maltohexaose methylthiazol-5- HMP-PP a RNA-DNA hybrid protein]-C-terminal-γ- an apurinic/ α-D-glucosamine tyr [+ 3 isozymes] BN140_RS05335 oxobutanoate -D-glucan octadecenedioate 40 in tRNA hexadec-7- octadec-9- oxooctadec- L-homoserine factor 420 BN140_RS07915 a [cysteine reductive cyclase BN140_RS02895 pyruvate alpha-glucan alpha-glucan GTP (L-glutamyl)-L-glutamate phosphoserine predicted cob(I)alamin acetyl-CoA thr 2-ketoisovalerate AMP-dependent 4-alpha- acyl-CoA semialdehyde-2-yl)-L-glutamateN-acetyl-gamma- yl)ethyl phosphate ribonuclease H: tRNA apyrimidinic site UDP-N- enoyl-[acp] enoyl-[acp] 11-enoyl-[acp] coenzyme F420 RS03565 desulfurase]-(S- ATP-dependent an oxidized carboxylase: L-alanine thiamine acetylglutamate short-chain short-chain short-chain phosphoserine homoserine tyrosine ABC adenolsyltransferase/ decarbonylase/ 2-phospho- threonylcarbamoyl- lys ferredoxin synthetase: glucanotransferase: synthetase: phosphorylase: phosphorylase: GTP BN140_RS07770 pseudouridine(13) acetylglucosamine hydrogenase Mo 2+ Mo 2+ precorrin-5 reductase subunit: factor 420 dTDP-L-rhamnose tryptophan-- BN140_RS09790 glutamyl-phosphate phosphate endonuclease V: decarboxylase sulfanyl) -[disordered- adenosylcobalamin D-glycerate Trp degradation IV BN140_RS12885 BN140_RS10790 kinase: dehydrogenase: dehydrogenase: dehydrogenase: phosphatase: dehydrogenase: transporter 2 cobinamide synthase complex a tRNA AMP synthase: lysine oxidoreductase: BN140_RS10470 BN140_RS10975 BN140_RS04930 cyclohydrolase ribonuclease HII: synthase TruD: BN140_RS01665 2-epimerase (non- subunit gamma: form scaffold BN140_RS01640 5'-phosphate biosynthesis I tRNA ligase: reductase: synthase: BN140_RS10875 BN140_RS10875 BN140_RS10875 BN140_RS09510 MfnA: of Mo2+ methylenetetrahydromethanopterin subunit alpha/beta: phosphoglycerate biotin carboxylase: decarboxylase: BN140_RS06645 [+ 3 isozymes] [+ 2 isozymes] [+ 2 isozymes] I FolE2: BN140_RS07885 BN140_RS00385 BN140_RS05935 hydrolyzing): BN140_RS11035 BN140_RS06870 ATP-dependent BN140_RS08540 BN140_RS01950 a reduced 4-alpha- [+ 3 isozymes] an [amino group carrierBN140_RS00370 protein]- α α BN140_RS00685 an [amino group carrier a 2'- a (3R,7Z)-3- a (3R,9Z)-3- a (3R,11Z)-3- BN140_RS02670 protein] complex Ni-sirohydrochlorin dehydrogenase: BN140_RS08370 BN140_RS11790 mutase: α-D- an L-tryptophanyl- L-threonylcarbamoyladenylate BN140_RS09795 ala ω-carboxy- -D- -D- thiamine 7,8- BN140_RS06855 a nucleoside 5'- BN140_RS04095 L-aspartate- adenolsyltransferase: adenosylcobalamin BN140_RS11265 + glucanotransferase: γ protein]-C-terminal- [+ 2 isozymes] deoxyribonucleoside [+ 5 isozymes] potassium- Trp H ferredoxin [iron- CO isobutanoyl-CoA 18-hydroxyoleoyl- C-terminal- -(5-phospho- glucopyranose maltopentaose glucopyranose maltotetraose DNA 38- hydroxy-hexadec- hydroxy-octadec- hydroxyoctadec- serine tyramine RS12960 a,c-diamide BN140_RS01760 glucopyranose [tRNA ] alanine cadaverine 2 AMP diphosphate AMP diphosphate (9Z)-octadec- phosphate dihydroneopterin formate monophosphate a pseudouridine semialdehyde a reduced + + BN140_RS09940 5'-phosphate 6 BN140_RS11290 γ [+ 3 isozymes] K transporting K a reduced N -L- oxaloacetate sulfur] cluster CoA L-glutamyl)-L-glutamate 1-phosphate 1-phosphate -(5-phospho-L- 5'-monophosphate α 7-enoyl-[acp] 9-enoyl-[acp] 11-enoyl-[acp] reductive cyclase phosphatase: 1-phosphate trp dehydrogenase: 9-enoyl-CoA 3'-triphosphate 40 in tRNA UDP-N-acetyl- - factor 420 ATPase precorrin-6A adenosyl- factor 420 molybdenum cofactor biosynthesis acetyl-CoA [+ 3 isozymes] glucose-1-phosphate threonylcarbamoyladenine a short glucan a short glucan glutamyl)-L-glutamate catalytic subunit: BN140_RS05340 malate BN140_RS09680 D-mannosamine a [cysteine desulfurase]- cobyrinate 3-phospho- thymidylyltransferase: synthase: BN140_RS07030 BN140_RS03605 dehydrogenase: pyruvate [scaffold protein- a,c-diamide pyruvate ferredoxin D-glycerate BN140_RS07120 an N 6 -L- RS07710 3 adenosylcobalamin RS12155 (2Fe-2S)] complex 15,17 -seco- cobyric acid oxidoreductase: 37 BN140_RS04270 a plant soluble a [protein]- a plant soluble a long-linear 4-methyl-5-(2- 5-(2-hydroxyethyl) a uridine 54 a [protein]-L- a (7Z)-3- a (6Z)-3- a protein a [protein]-L- cys GTP phosphoglycerate nucleotidyltransferase: threonylcarbamoyladenine phenylacetate 7-hydroxylaurate D-glucopyranose octanoate a [protein]-L-lysine a 3-oxotetracosanoyl- a ribonucleoside histidinol 3 threonine-- α phosphooxyethyl) HMP-PP methanophenazine 2-hydroxyisobutyramide oxohexacos- acrylamide F430-17 -acid synthase CobQ: ATP BN140_RS01185 BN140_RS07115 in tRNA heteroglycan L-glutamine heteroglycan -D-glucan -4-methylthiazole triphosphate in tRNA β-isoaspartate oxooctadec- with incorrect methionine precorrin-6B kinase: α thr (S)-malate alpha-glucan [acp] coenzyme BN140_RS01335 cysteine [+ 7 isozymes] dTDP- -D-glucose tRNA ligase: phenylacetate--CoA AMP-dependent 4-alpha- AMP-dependent transglutaminase: alpha-glucan thiazole thiamine methyl-viologen- hydroxyethylthiazole aspartyl/ tRNA protein-L- 7-enoyl-[acp] 6-enoyl-[acp] disulfide bonds peptide- aspartyl/ histidinol GTP 3',8- BN140_RS00865 short-chain transcriptional short-chain short-chain thiol reductase F430 synthase: (R)-1-amino- desulfurase NifS: BN140_RS11600 an L-threonyl- Carboxylate Degradation ligase: BN140_RS05640 synthetase: glucanotransferase: synthetase: BN140_RS03310 phosphorylase: phosphorylase: reducing glutamyl-tRNA pseudouridine(54/ isoaspartate O- methionine (S)-S- glutamyl-tRNA precorrin-6Y C5,15- a [co-chaperone]- tetrapyrrole biosynthesis cyclase MoaA: nucleoside- fumarate hydratase: phosphate kinase: regulator: dehydrogenase: 2+ 2+ phosphoglycerate Thr BN140_RS10790 dehydrogenase: dehydrogenase: dehydrogenase: thioredoxin: Cu RS10240 Cu RS10440 BN140_RS03610 2-propanol O adenosylcobyrate BN140_RS02350 pyruvate [tRNA ] [+ 5 isozymes] BN140_RS10470 BN140_RS10975 BN140_RS10470 transglutaminase: BN140_RS10790 synthase: hydrogenase BN140_RS00690 amidotransferase 55) synthase methyltransferase: oxide reductase: amidotransferase BN140_RS02480 methyltransferase [scaffold protein- I (from glutamate) BN140_RS05760 kinase: diphosphate BN140_RS04510 BN140_RS01690 -2-phosphate a tRNA Thr [+ 3 isozymes] 4-alpha- [+ 3 isozymes] BN140_RS07945 [+ 2 isozymes] [+ 2 isozymes] subunit delta: 4-methyl-5-(2- subunit A: BN140_RS10875 Pus10: BN140_RS07145 BN140_RS10875 BN140_RS10875 BN140_RS00570 BN140_RS11015 subunit A: (2Fe-2S)] complex oxidized [+ 3 isozymes] (8S)-3',8-cyclo-7,8- sugar epimerase: fumarate hydratase: acetate conversion a protein with an α α BN140_RS00685 a (3R)-3- a 2'- a protein L-β- a (3R,7Z)-3- a (3R,6Z)-3- a protein a protein-L- (decarboxylating) BN140_RS10835 diphosphate AMP phenylacetyl-CoA -D- -D- thiamine cobalamin adenosylcobalamin biosynthesis from cobyrinate a,c-diamide II an [L-cysteine a carboxy-adenylated dihydroguanosine to acetyl-CoA glucanotransferase: 6 γ a plant soluble a long-linear BN140_RS08640 phosphooxyethyl) BN140_RS11630 deoxyribonucleoside BN140_RS01520 BN140_RS11630 his 2+ 2+ subunit CbiT: coenzyme F430 Glu BN140_RS08955 BN140_RS04515 7-hydroxylauroyl- N -( -glutamyl)- hydroxytetracosanoyl- 54 isoaspartate hydroxyhexacos- hydroxyoctadec- with correct methionine- Cu RS02465 Cu SSQ1 chaperone: Respiration AMP diphosphate diphosphate AMP octanoyl-CoA glucopyranose heteroglycan glucopyranose α phosphate 2-hydroxy-2- a pseudouridine biosynthesis desulfurase]-S- [small subunit of 5'-triphosphate BN140_RS11290 -D-glucan dihydromethanophenazine thiazole [acp] 5'-triphosphate α-methyl ester disulfide bonds (S)-S-oxide acrylate nitrate RS04525 nitrate BN140_RS07905 BN140_RS11345 glutamate-- 13-DPG nucleotide sugar Inorganic Nutrient CoA a plant soluble L-lysine crosslink 1-phosphate 1-phosphate methylpropanoate in tRNA 7-enoyl-[acp] 6-enoyl-[acp] protein CobD: cob(II)yrinate sulfanyl-L-cysteine molybdopterin synthase] cyclic pyranopterin fumarate acetate maltose tRNA ligase: epimerase: Metabolism heteroglycan cobalt-precorrin- a [chaperone-ATP]- BN140_RS00035 a,c-diamide phosphoenolpyruvate methanogenesis from H and CO + + BN140_RS02855 monophosphate serine-- 2 2 acetyl-coenzyme an anion RS12810 an anion Na RS11390 Na [co-chaperone]- an L-glutamyl- synthase: type I BN140_RS08990 ser fumarate reductase 7 (C(5))- adenosyl- synthase MoaC: CO A synthetase: nitrogen fixation siroheme biosynthesis Glu 2 glyceraldehyde- tRNA ligase: methyltransferase: [scaffold protein- cobinamide [tRNA ] pyruvate kinase: BN140_RS02665 dTDP-4-dehydro- subunit A: a 2-methyl a (7Z,10Z,13Z,16Z β a (7Z)-3- an (11Z)-3- BN140_RS03835 3-phosphate BN140_RS04340 CO BN140_RS00165 I (ferredoxin) a nascent peptidoglycan a very-long- sn-glycero-3- -D-glucose an oxidized an organic a [protein]-L- (indol-3-yl) a [protein]-L- + α an L-seryl- 2 a peptidoglycan with (L- a maltodextrin a 3-oxotetradecanoyl- a cis-delta19-3- NAD chloride RS01805 chloride BN140_RS07940 (2Fe-2S)] complex phosphate a thiocarboxylated BN140_RS12160 phosphoenolpyruvate carbonic 6-deoxy- -D- BN140_RS00510 γ branched 2,3,4- a [histone]-L-lysine ,19Z)-3-oxodocosa- 4-guanidinobutyramide ω a 3-oxoacyl-[acp] oxotetradec- oxo-icos-11- acetamide glutamyl-tRNA dehydrogenase: ser [+ 4 isozymes] γ with (L-alanyl- -D- chain fatty acid phosphoethanolamine ATP H O 6-phosphate factor 420 hydroperoxide proline ( = 180) acetamide methionine an anion RS06525 an anion 5,6-dimethylbenzimidazole cob(I)yrinate cyclic pyranopterin anhydrase: glucopyranose [tRNA ] alanyl- -D-glutamyl-meso alpha-glucan 2 [acp] oxo-C38:1-[acp] uroporphyrinogen-III 5-deoxyadenosylcobinamide [small subunit of synthase: ser formylmethanofuran N acyl-CoA saturated fatty acid tRNA uridine(34) 5- glycerophosphoryl 7,10,13,16,19-pentaenoyl-[acp] LLM class F420- alkylhydroperoxidase: aspartyl/ peptidyl-prolyl cis- aspartyl/ 7-enoyl-[acp] enoyl-[acp] peptide- aspartyl/ ATP-NAD kinase: reductase: BN140_RS10810 a tRNA succinate acetyl-CoA 2 glutamyl-meso-2,6- AMP-dependent precorrin-7 SSQ1 chaperone a,c-diamide phosphate BN140_RS09590 -2,6-diaminopimeloyl- phosphorylase: short-chain ATPase: short-chain short-chain short-chain short-chain short-chain Ca 2+ RS01905 Ca 2+ uroporphyrinogen III phosphate BN140_RS09560 molybdopterin synthase] BN140_RS10800 dehydrogenase subunit Ni-sirohydrochlorin a,c- diaminopimeloyl-D-alanyl- synthetase: synthetase: carboxymethylaminomethyl diester dependent BN140_RS00430 glutamyl-tRNA trans isomerase: glutamyl-tRNA methionine (R)-S- glutamyl-tRNA BN140_RS07555 ATPase: D-alanine) tetrapeptide BN140_RS10790 dehydrogenase: BN140_RS00645 dehydrogenase: dehydrogenase: dehydrogenase: dehydrogenase: dehydrogenase: methyltransferase: nucleotidyltransferase: cob(I)alamin glyceraldehyde- E: BN140_RS11690 succinyl-CoA diamide reductive cyclase serineD-alanine) hydrolase: pentapeptide BN140_RS04930 modification radical phosphodiesterase: oxidoreductase: alkylhydroperoxidase: amidotransferase BN140_RS05890 amidotransferase oxide reductase: amidotransferase NAD(+) kinase: an anion RS12880 an anion precorrin-6Y C5,15- BN140_RS11345 (S)-4-amino-5- hydrogencarbonate BN140_RS10470 BN140_RS08215 molybdopterin 3-phosphate dTDP-4-dehydro- a nascent peptidoglycan SAM/GNAT enzyme BN140_RS11130 [+ 2 isozymes] BN140_RS10875 [+ 12 isozymes] BN140_RS05690 subunit A: BN140_RS10875 subunit A: BN140_RS10875 BN140_RS10875 BN140_RS10875 BN140_RS10875 BN140_RS11505 subunit A: methyltransferase BN140_RS11060 adenolsyltransferase/ [+ 14 isozymes] synthetase: ATP-dependent reductase BN140_RS04335 [+ 3 isozymes] [+ 3 isozymes] α a (3R,7Z,10Z,13Z,16Z 6-phospho BN140_RS06455 a (3R)-3- [+ 4 isozymes] a (3R)-3- a (3R,7Z)-3- a cis-delta19-3- a (3R,11Z)-3- a protein-L- BN140_RS09495 oxopentanoate synthase: a 2-methyl -D- + α triose-phosphate dehydrogenase: β-L-rhamnose D-ala with D,D cross-links (meso- Elp3: BN140_RS07340 sn-glycerol H phosphate ADP a reduced BN140_RS11630 a [protein]-L- BN140_RS11630 BN140_RS11630 + (decarboxylating) a [chaperone- [+ 2 isozymes] adenosylcobinamide- -ribazole cobinamide BN140_RS04480 subunit: BN140_RS01640 a very-long-chain ethanolamine ,19Z)-3-hydroxydocosa- D-glucono- an alcohol hydroxytetradecanoyl- hydroxyacyl-[acyl- hydroxytetradec- hydroxyC38:1- hydroxy-icos- methionine- NADP aspartate BN140_RS10745 pyruvate isomerase: BN140_RS12985 proline-- a formylmethanofuran AMP diphosphate branched a [histone]-N 6 - 3-phosphate glucopyranose a maltodextrin proline (ω = 0) glycine glycine a corrin RS08755 a corrin subunit CbiT: an [2Fe-2S] precorrin-1 GDP 5'-phosphate ATP-dependent NAD(P)-dependent pro BN140_RS04485 ammonium diaminopimelate containing) fatty acyl-CoA AMP diphosphate 7,10,13,16,19-pentaenoyl-[acp] factor 420 1,5-lactone 4-guanidinobutanoate [acp] (indol-3-yl)acetate carrier protein] 7-enoyl-[acp] [acp] 11-enoyl-[acp] (R)-S-oxide acetate RS09625 ADP]-[disordered- aminotransferase phosphoenol phosphoenolpyruvate carboxylase: BN140_RS10115 tRNA ligase: 2,3,4-saturated acetyl-L-lysine 1-phosphate betaine betaine BN140_RS07905 cluster protein adenolsyltransferase: D-glyceraldehyde oxidoreductase: form scaffold uroporphyrinogen III family protein: pyruvate BN140_RS09790 DHAP BN140_RS07375 formylmethanofuran-- fatty acyl-CoA BN140_RS09940 molybdopterin carboxylase: 3-phosphate BN140_RS04085 an L-prolyl- succinyl-CoA cobalt-precorrin- protein] complex adenosylcobinamide- tetrahydromethanopterin methyltransferase: BN140_RS09570 BN140_RS07260 biotin carboxylase: dTDP-β-L- [tRNA Pro ] glycine glycine GDP adenosyl- CO fixation into RS00415 7 (C(5))- non-chaperonin Pro N-formyltransferase: 2-oxoglutarate 2 2+ 2+ BN140_RS08215 BN140_RS09795 rhamnose a tRNA RNase III mRNA a [glycine-cleavage a (5Z)-3- betaine betaine Ni RS03940 Ni ribazoletransferase: cobyrinate 5-aminolevulinate synthase: oxaloacetate (anaplerotic) phosphatidylglycerophosphate a 2,3,4-saturated N-succinyl-L,L-2,6- methyltransferase: molecular BN140_RS08610 2-methylbutanoate 5'-deoxyadenosine an alkylated DNA a glycerophosphodiester glycerophosphoglycerol 6 3-phosphonopyruvate a 3-oxooctadecanoyl- a 3-oxodecanoyl- a cis-delta21-3- seleno-L- uroporphyrin-III C- a,c-diamide phosphopyruvate fatty acid processing complex H protein] N oxidized ser oxotetracos- asp met L-dopa BN140_RS07940 chaperone BN140_RS05335 fructose- BN140_RS01180 (1-octadecenoyl(9Z), 2-palmitoyl) GTP [acp] diaminopimelate [acp] oxo-C40:1-[acp] homocysteine methyltransferase: cobyric acid delta-aminolevulinic oxaloacetate acetyl-coenzyme acyl-CoA substrate methylthioadenosine DNA-3- glycerophosphoryl glycerophosphoryl -dihydrolipoyl-L-lysine thiamine coenzyme F -2 aspartate 5-enoyl-[acp] molybdopterin hydratase: bisphosphate 5-formyl-tetrahydromethanopterin CO ribonuclease III: pyridine nucleotide- 420 aspartate a cation RS01650 a cation ATPase: UDP-N-acetyl-D- [+ 5 isozymes] 2 short-chain serine short-chain short-chain short-chain methionine ornithine aromatic acid precorrin-8x BN140_RS09580 synthase CobQ: acid dehydratase: BN140_RS02895 phosphatidylglycerophosphatase A synthetase: synthetase: BN140_RS00155 phosphorylase: methyladenine diester diester disulfide pyrophosphate- coenzyme F390 aminotransferase BN140_RS11345 adenosylcobalamin adenine dinucleotide aldolase: carbonic anhydrase: dehydrogenase: acetyltransferase: dehydrogenase: dehydrogenase: dehydrogenase: aminotransferase: synthase: acetyltransferase: decarboxylase: BN140_RS01335 BN140_RS09565 glucosamine biosynthesis I phenylalanine- methenyltetrahydromethanopterin 2-oxoglutarate A: BN140_RS05340 BN140_RS00165 BN140_RS04930 BN140_RS05395 glycosylase: phosphodiesterase: phosphodiesterase: oxidoreductase: binding protein: synthetase: family protein: an [Fe-S cluster a [disordered- precorrin-2 5'-phosphate FMNH molybdopterin BN140_RS10135 BN140_RS09590 ribonuclease III: BN140_RS04615 RS10055 precorrin-8X (R)-1-amino- 2 -tRNA ligase: [+ 4 isozymes] [+ 3 isozymes] BN140_RS04915 BN140_RS11130 BN140_RS11130 BN140_RS00280 BN140_RS11830 BN140_RS10875 BN140_RS02400 BN140_RS13545 BN140_RS10875 BN140_RS10875 BN140_RS10875 BN140_RS06755 BN140_RS00380 BN140_RS06715 D-glucopyranose phe cyclohydrolase: BN140_RS00695 1-oleoyl-2-palmitoyl- BN140_RS07645RNase III 5-deoxy-α-ribose a DNA containing a [glycine-cleavageBN140_RS02260 a (3R)-3- a (3R)-3- a (3R,5Z)-3- a cis-delta21-3- [+ 3 isozymes] a cation RS06175 a cation biosynthesis form [Fe-S] cluster porphobilinogen molybdenumtransferase [+ 2 isozymes] hydrogencarbonate adenine an alkylated sn-glycerol sn-glycerol N-succinyl-2-amino- N-acetyl-L- methylmutase: adenosylcobalamin 2-propanol O adenosylcobyrate 6-phosphate BN140_RS08530 methenyltetrahydromethanopterin 2-methylbutanoyl- a 2,3,4-saturated 1-phosphate an apurinic/ an alcohol glycerol complex H protein] phosphonoacetaldehyde [+ 3 isozymes] hydroxyoctadecanoyl- O-acetyl-L-serine hydroxydecanoyl- hydroxytetracos- hydroxyC40:1- SeMet dopamine chaperone]-ATP scaffold protein] siroheme synthase: MoeA: BN140_RS00990 2-phospho- glucose-6- phosphatidylglycerol an mRNA fragment processing 3-phosphate 3-phosphate 6-ketopimelate oxaloacetate BN140_RS07930 5'-phosphate -2-phosphate BN140_RS08535 AMP diphosphate AMP diphosphate nucleobase 6 coenzyme F -G methionine hydroxymethylbilane an L-phenylalanyl- cyclohydrolase: BN140_RS08890 phosphoenolpyruvate CoA fatty acyl CoA apyrimidinic site N -lipoyl-L-lysine 390 [acp] [acp] 5-enoyl-[acp] [acp] BN140_RS09555 [+ 2 isozymes] D-glycerate phosphate product mRNA phosphatase: cobalamin [tRNA Phe ] a cation RS00450 a cation hydrogenobyrinate synthase: carboxylase: BN140_RS05340 MoO -molybdopterin phosphoglycerate β-D-fructose 1,6- isomerase: a tRNA Phe H 5,10-methenyltetrahydromethanopterin formate RS06950 sirohydrochlorin biosynthesis 5,6-dimethylbenzimidazole BN140_RS09575 2 hydroxymethylpyrimidine 2 BN140_RS07260 cofactor mutase: bisphosphate BN140_RS02220 oxidation to CO Ni-sirohydrochlorin protein CobD: salvage 2 adenosylcobalamin a (1->4)- a [2-oxoglutarate a 2'- 1-deoxy-L- a peptide with a uridine 13 a cytidine D-glyceraldehyde 4-amino-2-methyl-5- siroheme synthase: BN140_RS00035 preuroporphyrinogen BN140_RS01760 fructose 1,6- glucose-6- oxaloacetate 1-(3-sn-phosphatidyl)- α-linolenate isobutanoate an oxidized ADP-α-D-glucose a 3-oxohexacosanoyl- a cis-delta11-3- a cation RS12165 a cation a,c-diamide α dehydrogenase E2 protein] deoxyribonucleoside [DNA] ARP glycero-tetrulose phosphoenol 56 pro riboflavin diphosphomethylpyrimidine 4-amino-2-methyl-5- formate sn-glycerol 3-phosphate a primary alcohol -D-glucan dGTP an N-terminal dADP in tRNA in tRNA 3-phosphate phe a microtubule L-ornithine BN140_RS09555 adenosyl- [+ 3 isozymes] bisphosphatase: phosphate cytochrome c550 6 [acp] oxo-C30:1-[acp] formate RS04215 formate synthase: uroporphyrinogen III pyrimidinemethanol acyl-CoA synthetase: acetyl-coenzyme glycosyltransferase N -dihydrolipoyl-L-lysine 5'-triphosphate 4-phosphate L-leucine pyruvate tRNA tRNA (cytidine(56) glyceraldehyde- biosynthesis cobinamide BN140_RS06475 isomerase: sulfurtransferase quinoprotein pyridine nucleotide- metal-dependent DNA polymerase 6,7-dimethyl-8- Zn-dependent aspartate pyrroline-5- BN140_RS03600 α methyltransferase: bifunctional 3-phospho- methionine-- phosphatidylglycerophosphatase BN140_RS04930 A synthetase: WbuB: short-chain pyruvate kinase: pseudouridine(13) -2'-O)- 3-phosphate short-chain alanine riboflavin kinase: siroheme phosphate -ribazole BN140_RS10435 met 5,10-methylene-tetrahydromethanopterin a reduced factor 420 FdhD: ethanol disulfide phosphohydrolase: subunit beta: ribityllumazine exopeptidase M28: aminotransferase: carboxylate ATPase: sulfate RS12680 sulfate cobyrinic acid a,c- AIR hydroxymethylpyrimidine D-glycerate tRNA ligase: A: BN140_RS05340 [+ 3 isozymes] BN140_RS00165 BN140_RS07095 dehydrogenase: BN140_RS12160 synthase TruD: methyltransferase: dehydrogenase: dehydrogenase: dehydrogenase: BN140_RS12380 5'-phosphate BN140_RS08215 F6P F6P BN140_RS02360 dehydrogenase: oxidoreductase: BN140_RS01955 synthase: BN140_RS00350 BN140_RS04615 reductase: BN140_RS06780 phosphomethylpyrimidine 5-deoxyadenosylcobinamide kinase/ BN140_RS01265 an L-methionyl- BN140_RS02015 BN140_RS10875 BN140_RS05935 BN140_RS09275 BN140_RS12985 BN140_RS10875 BN140_RS09680 RS09550 diamide synthase: triose-phosphate [+ 3 isozymes] [+ 4 isozymes] BN140_RS11210 a (1->4)- a [2-oxoglutarateBN140_RS02260 [+ 7 isozymes] BN140_RS07445 a (3R)-3- a 2'-O- a cis-delta11-3- BN140_RS10180 synthase: BN140_RS06450 phosphate α-ribazole-5'-P uroporphyrinogen-III phosphomethylpyrimidine [elongator 5,10-methylenetetrahydromethanopterin an L-1-phosphatidyl- AMP diphosphate α-linolenoyl-CoA ADP 2'-deoxyguanosine PPP leu a peptide dATP pyruvate a pseudouridine 13 [+ 3 isozymes] FMN BN140_RS12135 glucose-6- i 6,7-dimethyl-8-(1- 56 (S)-1-pyrroline- an α/β tubulin isomerase: glutamine--fructose- Met CO a reduced α-D-glucan keto- sulfate RS02525 sulfate elongator 2 sn-glycerol an aldehyde dehydrogenase E2 [DNA] hydroxyhexacosanoyl- methylcytidine 13-DPG hydroxyC30:1- pro [+ 2 isozymes] nucleotidyltransferase: phosphatase: kinase: BN140_RS05065 phosphate tRNA ] reductase: BN140_RS08360 isobutanoyl-CoA AMP diphosphate D-ribityl)lumazine in tRNA 5-carboxylate heterodimer hydrogenobyrinate adenosylcobalamin BN140_RS10115D-glyceraldehyde 6-phosphate tRNA Met cytochrome c550 protein] N 6 -lipoyl-L-lysine [acp] in tRNA phenylpyruvate [acp] HMP-P BN140_RS11060 BN140_RS05340 HMP-P DHAP isomerase: a,c-diamide salvage from cobalamin 3-phosphate aminotransferase: adenosylcobinamide- α BN140_RS02220 N 5 -methyltetrahydromethanopterin RS04415 protoporphyrin phosphomethylpyrimidine geranylgeranyl -ribazole phosphomethylpyrimidine BN140_RS07110 predicted diphosphate biosynthesis cob(I)alamin GDP glucose-6- ABC IX magnesium kinase: BN140_RS05730 kinase: BN140_RS05730 D-glucosamine 2+ 2+ peptidase U62: an [apo BCAA a guanine 10 a guanine 34 (indol-3- a debranched 6-carboxy-5,6,7,8- Zn Zn cob(I)alamin phosphate 6-phosphate maltopentaose D-glucopyranose phytenate pristanate a [histone]-N 6 -acetyl-L-lysine coenzyme A a 3-oxohexadecanoyl- (R)-mevalonate a cis-delta15-3- thiamine an unfolded a nucleoside transporter chelatase: bifunctional bifunctional Lys pyruvate dehydrogenase E2 protein] queuine uroporphyrinogen-III cobalt-precorrin-4 α 13-DPG 2-oxoglutarate (2E,6E)-farnesyl adenosylcobinamide- fructose- a tRNA BN140_RS00785 in tRNA in tRNA yl)pyruvate -limit dextrin tetrahydropterin phosphate diphosphate adenolsyltransferase/ isomerase: lysine--tRNA ligase: 6 [acp] alpha-glucan oxo-C34:1-[acp] protein of Zn2+ BN140_RS01100 hydroxymethylpyrimidine GDP hydroxymethylpyrimidine phosphoglucosamine 4-alpha-glucanotransferase: acyl-CoA synthetase: AMP-dependent pyruvate ferredoxin histone deacetylase: N -dihydrolipoyl-L-lysine tRNA-guanine(15) indolepyruvate cobalt-precorrin- 7-carboxy-7- nucleoside- diphosphate bisphosphate BN140_RS10435 tetrahydromethanopterin pyridine nucleotide- tRNA (guanine(10)-N(2) uroporphyrinogen glyceraldehyde- thiamine- homocitrate RS06210 farnesyltranstransferase: cobinamide mutase: BN140_RS12295 BN140_RS10975 BN140_RS04930 synthetase: oxidoreductase: transglycosylase: oxidoreductase: short-chain 4 C(11)- mevalonate kinase: phosphorylase: deazaguanine short-chain Zn 2+ RS10265 Zn 2+ cobaltochelatase kinase/ ribazoletransferase: kinase/ aldolase: an L-lysyl- methyl-coenzyme BN140_RS07085 disulfide )-dimethyltransferase: decarboxylase: 3-phosphate chaperonin GroL: diphosphate synthase: ATP-dependent Lys S-methyltransferase: BN140_RS02880 BN140_RS10790 dehydrogenase: phosphate kinase: subunit CobN: phosphomethylpyrimidine BN140_RS02860 BN140_RS05335 phosphomethylpyrimidine D-glucopyranose BN140_RS07125 [tRNA ] 4-alpha-glucanotransferase: [+ 3 isozymes] BN140_RS10470 BN140_RS01185 histone deacetylase: BN140_RS10095 BN140_RS04305 dehydrogenase: methyltransferase: synthase: kinase: BN140_RS10135 M reduction BN140_RS08690 oxidoreductase: BN140_RS03755 BN140_RS06075 dehydrogenase: BN140_RS02200 BN140_RS08160 aksA kinase: BN140_RS05065 adenolsyltransferase: kinase: BN140_RS05065 6-phosphate lys BN140_RS11290 an N 2 - BN140_RS10875 BN140_RS07915 [+ 2 isozymes] BN140_RS07230 BN140_RS10875 BN140_RS11740 GGPP [+ 2 isozymes] phosphoglucosamine to methane [+ 3 isozymes] [+ 7 isozymes] BN140_RS08815 an [apo BCAABN140_RS02260 a queuosine 34 [+ 2 isozymes] a (3R)-3- (R)-mevalonate BN140_RS12985 a cis-delta15-3- BN140_RS03430 BN140_RS09940 BN140_RS08695 AMP phytenoyl-CoA 10 guanine S-2-(indol-3 coproporphyrinogen III cobalt- α-D-glucopyranose 7-carboxy-7- thiamine (2R)-homocitrate mutase: maltose diphosphate a reduced acetate a [histone]-L-lysine dimethylguanine D-glyceraldehyde a nucleoside cob(II)yrinate methyl-CoM BN140_RS08700 maltotetraose CO acetyl-CoA dehydrogenase E2 in tRNA hydroxyhexadecanoyl- 5-phosphate hydroxyC34:1- a protein RS01775 HMP-PP adenosylcobalamin adenosylcobalamin HMP-PP 2 yl)acetyl-CoA precorrin-5A 1-phosphate deazaguanine diphosphate RS06325 BN140_RS05585 AMP diphosphate pristanoyl-CoA flavodoxin 6 in tRNA 3-phosphate triphosphate a,c-diamide 50S ribosomal BN140_RS08705 protein] N -lipoyl-L-lysine [acp] [acp] D-glucosamine β-D-fructose 1,6- protein L13: BN140_RS08710 1-phosphate histidine-- bisphosphate his BN140_RS02915 BN140_RS08715 tRNA ligase: glucose-1-phosphate BN140_RS08720 an O 4 - a nascent peptidoglycan a [pyruvate dehydrogenase 3-deoxy-D-arabino- an N-acyl-D- β [+ 7 isozymes] + an (S)-2- + an intra- a [protein]-α- -D-glucose cytosine RS11670 thymidylyltransferase: BN140_RS04010 an L-histidyl- maltohexaose maltose NADH menadione H a [protein]- γ a [protein]-L-glutamine serotonin 6 FMNH NADP a cytosine in DNA a [protein] Ser/Thr cobalt-precorrin-7 DNA with lesion glutathione a cis-delta13-3- RS05610 methane BN140_RS08725 methylthymine with (L-alanyl- -D-glutamyl- E2 protein] N - bis(molybdenum halocarboxylate 2 heptulosonate protein disulfide mannosamine L-glutamate 6-phosphate Amino Acid Biosynthesis His L-cysteine GTP oxo-C32:1-[acp] tRNA-specific BN140_RS07120 [tRNA ] 4-alpha-glucanotransferase: NADH dehydrogenase in DNA meso-2,6-diaminopimeloyl-D- transglutaminase: dihydrolipoyl-L-lysine cofactor) haloacid iron-sulfur serine/threonine cobalt-precorrin- 7-phosphate excinuclease ABC: pyridine nucleotide- inositol-3- His methylated-DNA- pyridine nucleotide- site-specific DNA- sugar kinase: chemotaxis adenosine N-acetyl-α-D- a tRNA methyl-CoM BN140_RS10975 (quinone): BN140_RS07660 alanyl-D-alanine) pentapeptide BN140_RS03310 molybdenum cofactor dehalogenase: flavoprotein: protein kinase: 7 (C(5))- 3-dehydroquinate BN140_RS09350 glutaredoxin: disulfide short-chain phosphate F6P -protein-cysteine serine hydrolase: disulfide methyltransferase: BN140_RS12915 protein CheR: deaminase: L-histidine biosynthesis glucosamine 4-alpha-glucanotransferase: guanylyltransferase: BN140_RS01905 BN140_RS05295 BN140_RS07030 methyltransferase: synthase II: BN140_RS09355 BN140_RS00460 oxidoreductase: dehydrogenase: synthase: L-arginine biosynthesis I (via L-ornithine) L-arginine biosynthesis II (acetyl cycle) L-tryptophan biosynthesis diphthamide L-glutamate NADH dehydrogenase: methyltransferase: a nascent peptidoglycanBN140_RS04335 transglutaminase: oxidoreductase: BN140_RS10035 BN140_RS06365 BN140_RS04405 RS03570 L-isoleucine 1-phosphate BN140_RS11290 BN140_RS04245 BN140_RS07940 BN140_RS10145 BN140_RS09360 two reduced BN140_RS07690 BN140_RS10875 an N-acyl-α-D- a [protein]-L- BN140_RS09525 biosynthesis (archaea) biosynthesis III glucose-6- BN140_RS07680 BN140_RS04235 with (L-alanyl-γ-D-glutamyl- BN140_RS07945 BN140_RS02260 bis(guanylyl [+ 4 isozymes] [+ 6 isozymes] an N 4 -methylcytosine [+ 6 isozymes] a cis-delta13-3- biosynthesis II 6 5 uracil RS08770 N-acetylglucosamine- + a [protein]-S- D-ala a [protein] N -[(5-hydroxy-1H a [pyruvate dehydrogenase an (R)-2- + a [protein] (L-serine/L- 3-dehydroquinate DNA without cysteine residues mannosamine glutamate-O PRPP N-acetylglutamyl- an L-histidine- phosphate D-glucopyranose maltoheptaose menadiol NAD a thymine in DNA meso-2,6-diaminopimeloyl- molybdopterin cofactor) a halide anion H NADPH FMN in DNA cobalt-precorrin-8 GSSG hydroxyC32:1- Ins(3)P -indol-3-yl)ethyl]-L-glutamine 6 hydroxyacid lesion Glu gln isomerase: 1-phosphate glycine-- Pentose Phosphate Pathways methyl-L-cysteine E2 protein] N -lipoyl-L-lysine threonine) phosphate in a protein 6-phosphate -methyl-ester pyruvate phosphate N-acetyl-gamma- [translation 2-oxoglutarate gly D-alanine) tetrapeptide [acp] ATP BN140_RS02220 uridyltransferase: tRNA ligase: 2-isopropylmalate glutamyl-phosphate elongation factor2-(3-amino-3- 2] FMN-binding RS09785 phosphoribosyltransferase: ornithine glutamate synthase BN140_RS07120 BN140_RS06055 synthase: reductase: anthranilate synthase: carboxypropyl) glucose-6- Gly pentose phosphate pathway 6 BN140_RS04465 acetyltransferase: UDP-N-acetyl- a glycyl-[tRNA ] an O - a tRNA precursor 34 a [DNA]-3'- β N-acetyl-D- uridine family protein: (oxidative branch) II D-glucopyranose a [protein]- a guanine an N-modified a 5'-phospho- (R)-N-formyl- - a [protein] (L-serine/L- a cis-delta17-3- RS05145 BN140_RS11370 BN140_RS00370 BN140_RS07520 histidine synthase: phosphate α maltohexaose methylguanine N5-CAIR preQ phosphoenol an acyl phosphate pyruvate D-ala Ins(1)P prephenate ATP BN140_RS00380 BN140_RS01200 -D-glucosamine a tRNA Gly a tRNA precursor CTP ATP with a 5' in tRNA 1 hydroxyl [DNA] NMN ATP hydroxy-L-kynurenine dGDP threonine) phosphate mannosamine ATP (R)-citramalate a 2-[(3S)-3-amino-BN140_RS02680 isomerase: 4-alpha-glucanotransferase: L-cysteine aminoacyl-[tRNA] kynurenine oxo-C36:1-[acp] phosphoribosyltransferase: in DNA extension and a phosphoribosylaminoimidazole tRNA-guanine(15) peptidyl-tRNA DNA ligase: pyruvate prephenate uridine kinase: N-acetyl-L- ornithine acetylglutamate anthranilate 3-carboxypropyl]-L- [+ 2 isozymes] BN140_RS10435 F6P methylated-DNA- protein acylphosphatase: pyruvate oxidase: D-alanine--D- myo-inositol-1(or 4)- short-chain sugar kinase: L-aspartate BN140_RS10975 CCA tRNA short 3' extensionribonuclease P: transglycosylase: BN140_RS02595 nicotinamide-nucleotide formamidase: pyruvate kinase: BN140_RS01655 RS03000 BN140_RS12425 3-isopropylmalate glutamate acetyltransferase: kinase: histidine-[translation 6-phospho-3- -protein-cysteine carboxylase catalytic hydrolase: phosphatase: BN140_RS05595 monophosphatase: dehydratase: BN140_RS12915 anthranilate Glu biosynthesis D-glucopyranose 4-alpha-glucanotransferase: nucleotidyltransferase: BN140_RS10095 adenylyltransferase: BN140_RS07140 BN140_RS07830 alanine ligase: dehydrogenase: adenylyl cyclase: dehydratase: BN140_RS00385 N-acetyl-L- methyltransferase: BN140_RS01455 subunit: BN140_RS07430 BN140_RS05940 DNA ligase (ATP) BN140_RS12160 BN140_RS10155 1-(5-phospho- BN140_RS00380 N-acetyl-L- elongation factor 2] 6-phosphate hexuloisomerase: a tRNA BN140_RS01675 a 7-aminomethyl-7- (R)-β-hydroxy- BN140_RS03905 [+ 3 isozymes] BN140_RS08860 BN140_RS09490 BN140_RS10875 N-acetyl-D- BN140_RS09325 UMP acetylglutamate Glu glutamate 5- phosphoribosyltransferase: BN140_RS11290 a[+ tRNA 3 isozymes] precursor an N-modified an uncharged : BN140_RS06885 BN140_RS03995 β-D-ribosyl)-ATP BN140_RS01575 BN140_RS03495 BN140_RS04235 34 + formate pyruvate a cis-delta17-3- keto- RS11680 kinase: glutamate BN140_RS07530 diphthine synthase: oxaloacetate methionine-- containing a a [protein]-S- CAIR guanine deazaguanosine amino acid tRNA NAD L-kynurenine dGTP a [protein] Ser/Thr a carboxylate acetyl phosphate D-alanyl-D-alanine myo-inositol mannosamine BN140_RS01580 semialdehyde met maltose maltopentaose a guanine in DNA a tRNA fragment with a short [DNA] hydroxyC36:1- phenylpyruvate cyclic-AMP phosphoribosyl- BN140_RS00385 BN140_RS03050 aspartate tRNA ligase: 6-phospho-3- 3' CCA end methyl-L-cysteine in tRNA 6-phosphate NADH repair 3' extension [acp] RS04595 3-isopropylmalate N-(5-phosphoribosyl)-anthranilate BN140_RS01265 hexuloisomerase: ATP N-acetylglutamyl- aminotransferase: an L-methionyl- dehydratase: N-acetylornithine a diphthine-[translation Met BN140_RS05855 diphosphatase: phosphate BN140_RS04615 [initiator tRNA ] phosphoribosylanthranilate elongation factor 2] Aromatic Compound Biosynthesis Met hexulose 6- NADH BN140_RS08575 ornithine aminotransferase: 26 an N-terminal- BN140_RS03080 [+ 3 isozymes] initiator tRNA (R)-1- (2-carboxy-2,5-dihydro- a guanine / a dolichyl MoO - an insertion sequence a myo-inositol 2-hydroxy-2- cobalt- a supercoiled 7-carboxy-7- a [protein]- RS08045 isomerase: BN140_RS01245 phosphate maltotetraose D-glucopyranose quinoxaline-2- adenosylcobyrate maltotetraose α 2 N-formylkynurenine [DNA] β BN140_RS08580 N-acetyl-gamma- gln acetyltransferase: BN140_RS02400 acyl-carrier protein 27 UDP- -D-glucose L-methionyl-L- Ins(4)P Ins(6)P 1-(5-phospho- - L-tyrosine biosynthesis I asp carboxyl adenylate aminopropan-2-ol 5-oxofuran-2-yl)-acetate guanine in tRNA phosphate molybdopterin ATP element IS30 monophosphate methylpropanenitrile sirohydrochlorin duplex DNA deazaguanine L-histidine glutamyl-phosphate BN140_RS00380 N-(5'-phosphoribosyl) chorismate biosynthesis II (archaea) Fatty Acid and Lipid Biosynthesis 3-hexulose- 4-alpha-glucanotransferase: cobalamin alpha-glucan glycosyl valyl-[protein] kynurenine DNA polymerase 7-cyano-7- RS13145 D-ribosyl)-AMP citraconate acyl carrier protein: carboxymuconolactone tRNA (guanine(10)-N(2) cofactor type II methionyl transposase: myo-inositol-1(or 4)- precorrin-2 C(20)- myo-inositol-1(or 4)- myo-inositol-1(or 4)- helicase: histidine kinase: reductase: carbamoyl N-acetyl-L- anthranilate isomerase: 6-phosphate BN140_RS10975 biosynthesis phosphorylase: transferase: molybdenum cofactor formamidase: nitrilase: subunit beta: deazaguanine phosphoribosyl- a diphthamide- BN140_RS10475 decarboxylase family )-dimethyltransferase: aminopeptidase: BN140_RS04675 monophosphatase: methyltransferase: monophosphatase: monophosphatase: BN140_RS04230 BN140_RS00375 BN140_RS00370 phosphate ornithine BN140_RS07540 chorismate D-glyceraldehyde archaetidylserine and archaetidylethanolamine biosynthesis synthase: 4-alpha-glucanotransferase: protein CobD: BN140_RS12885 BN140_RS02445 guanylyltransferase: BN140_RS07140 BN140_RS03445 BN140_RS01955 synthase: AMP β-methyl-D-malate biotin-carboxyl carrier protein assembly a quinoxaline-2- protein: BN140_RS08135 BN140_RS03755 a dolichyl β- BN140_RS07995 [+ 8 isozymes] BN140_RS09490 BN140_RS07910 BN140_RS09490 BN140_RS09490 [+ 4 isozymes] [+ 23 isozymes] N-acetyl-L- synthase: [translation chorismate mutase: 3-phosphate (R)-NADHX [+ 2 isozymes] adenylyl BN140_RS04245 hydro-lyase (2- 1-(o-carboxyphenylamino)-1'- BN140_RS05370 BN140_RS11290 AMP carboxyl-[aryl- BN140_RS00035 an N 2 -dimethylguanine 26 an N-terminal formate an insertion 2-hydroxy-2- [+ 3 isozymes] a single BN140_RS07225 a [protein]- RS08920 cyclohydrolase: glutamate 5- elongation factor 2] (4,5-dihydro-5- α-D-glucopyranose UDP D-glucosyl molybdenum met L-kynurenine BN140_RS09605 deoxyribulose 5'-phosphate BN140_RS00390 bifunctional 2 27 L-valyl-[protein] sequence IS30 with myo-inositol cobalt-factor III myo-inositol myo-inositol a nucleoside 5'- N-phospho- RS01150 BN140_RS01305 methylmaleate- DHAP (Fe-S)-cluster maltose maltotriose carrier protein] adenosylcobinamide oxofuran-2-yl)-acetate /N -dimethylguanine maltotriose phosphate methylpropanoate stranded DNA preQ semialdehyde BN140_RS09610 a [biotin carboxyl-carrier protein]-L-lysine ADP-dependent 1-phosphate cofactor monophosphate 0 1-(5-phospho-β-D-ribosyl)- forming): indole-3-glycerol- prephenate assembly protein: integrated transposon L-histidine N-acetylornithine NAD(P)H-hydrate 5-[(5-phosphoribosylamino) BN140_RS01575 carbamoyl phosphate synthase: NAD(P)-dependent bifunctional biotin-- BN140_RS05685 aminotransferase: L-ornithine prephenate enolaldehyde dehydratase/ methylideneamino]imidazole- phosphate BN140_RS07535 glycerol-1- [acetyl-CoA-carboxylase] D-ribulose (2R,3S)-3- BN140_RS02400 hydrogencarbonate dehydrogenase: a (6S)-5- an N 2 -methylguanine 26 a tRNA a 5'-half-tRNA an N-terminal- an N-terminal- a [LuxE]- a long-chain a peptide with RNase II an organic phosphate formaldehyde NAD(P)H-hydrate a maltodextrin D-glucopyranose a glucan maltotriose a 3'-half-tRNA N-acetyl- roseoflavin RS04345 4-carboxamide methylmalate synthetase/biotin operon 5-phosphate 27 uroporphyrinogen-I 4-hydroxybenzoate Ins(2)P wound RNA RS02075 N-acetyl-L- (1S,2R)-1-C-(indol-3- BN140_RS10150 epimerase: DL-allothreonine formyltetrahydrofolate /guanine in tRNA precursor with molecule with L-methionyl-L- L-methionyl-L- L-cysteine fatty acid an N-terminal degradation hydroperoxide asp nickel transporter: carbamoyl dehydrogenase: molecule with L-citrulline 3-methylmalate yl)glycerol 3-phosphate repressor: BN140_RS09765 4-alpha-glucanotransferase: 4-alpha-glucanotransferase: serine 5-formyltetrahydrofolate a 5' extension a 2',3'-cyclic seryl-[protein]type II methionyl alanyl-[protein]type II methionyl acyl-protein uroporphyrinogen L-methioninetype II methionyl hypothetical RNA helicase: substrate mRNA ornithine BN140_RS07360 BN140_RS03830 tRNA (guanine(10)-N(2) ribonuclease P: a 5'-OH end acetylornithine myo-inositol-1(or 4)- BN140_RS03940 dehydrogenase: phosphate 4-hydroxyphenylpyruvate a [biotin carboxyl-carrier (S)-NADHX BN140_RS10975 BN140_RS10975 phosphate end synthetase: peroxiredoxin: riboflavin kinase: aspartate ornithine TrpB-like pyridoxal- β-D-fructose 1,6- hydroxymethyltransferase: cyclo-ligase: )-dimethyltransferase: BN140_RS01455 2'-5' RNA ligase: aminopeptidase: aminopeptidase: decarboxylase: deacetylase: aminopeptidase: protein: monophosphatase: BN140_RS03165 ribonuclease II: acetylornithine synthase: 6 BN140_RS10465 BN140_RS01845 BN140_RS12380 dehydrogenase: 1-(5-phosphoribosyl) BN140_RS08565 carbamoyltransferase: methylglyoxal protein]-N -biotinyl-L-lysine 4-alpha-glucanotransferase: 4-alpha-glucanotransferase: BN140_RS02745 BN140_RS06460 BN140_RS03755 BN140_RS01680 BN140_RS07995 BN140_RS07995 a [LuxE]-S- BN140_RS06075 BN140_RS05770 BN140_RS07995 BN140_RS06710 [+ 4 isozymes] BN140_RS12005 deacetylase: BN140_RS09605 phosphate tyrosine bisphosphate GGPP sn-glycerol 1-phosphate ATP-dependent [+ 3 isozymes] BN140_RS09490 BN140_RS04380 -5-((5- BN140_RS11290 BN140_RS11290 2 26 an uncharged a ligated tRNA an N-terminal an N-terminal L- RS11425 BN140_RS09655 dependent enzyme: aminotransferase: NADH-hydrate gly acetaldehyde a 5,10- an N dimethylguanine met met (long-chain fatty acetate L-citrulline a peptide met roseoflavin RS00580 2-oxobutanoate BN140_RS05770 BN140_RS09610 a tRNA fragment with a 2'-5' linkage coproporphyrinogen I phenol myo-inositol an unwound RNA a nucleoside 5'- an alcohol phosphoribosylamino) maltose a maltodextrin D-glucopyranose a glucan methenyltetrahydrofolate /guanine 27 in tRNA tRNA L-seryl-[protein] alanyl-[protein] acyl)-L-cysteine oxaloacetate BN140_RS07515 BN140_RS00015 geranylgeranylglyceryl/ dehydratase: monophosphate 5'-phosphate methylideneamino) carbamoyl acetolactate L-ornithine [+ 2 isozymes] heptaprenylglyceryl a [biotin carboxyl-carrier-protein BN140_RS03830 imidazole-4- synthase: phosphate tyr 6-deoxy-5-ketofructose phosphate synthase: dimer]-N 6 -biotinyl-L-lysine carboxamide isomerase: indole ser NADH RS12715 BN140_RS05650 L-citrulline BN140_RS11615 a reduced 57 a tRNA precursor 2 26 an N-terminal-L-methionyl- an N-terminal-L-methionyl- BN140_RS04460 L-lysine biosynthesis VI 1-phosphate an oxidized an adenine / an N dimethylguanine a single a ribonucleoside a double ADP-D-ribose (S)-2-aceto-2- N-formyl- a damaged a siderophore- succinate 5-hydroxy- RS03210 biotin carboxylase: biotin carboxylase: + 2-phosphoglycolate a cytosine in DNA Ins(5)P ornithine ser a tetrahydrofolate ferredoxin [iron- H adenine 58 in tRNA with a 5' /guanine 27 in tRNA L-cysteinyl-[protein] L-threonyl-[protein] stranded DNA hydroxybutanoate DNA pyrimidine mutated tRNA bound Fe(III) semialdehyde acetolactate 2-amino-3,7- BN140_RS09795 BN140_RS09795 thioredoxin stranded DNA triphosphate L-glutamate L-tryptophan phosphoribulosylformimino- carbamoyltransferase: L-leucine biosynthesis argininosuccinate sulfur] cluster extension and type II methionyl type II methionyl NUDIX hydrolase: synthase: TrpB-like pyridoxal- S-adenosyl-L-methionine cycle I dideoxy-D-threo- GGGP serine ferredoxin:thioredoxin protein-L-isoaspartate tRNA (guanine(10)-N(2) DNA primase: DNA helicase ketol-acid phosphoglycolate N-formylglutamate myo-inositol-1(or 4)- 8-oxoguanine aldehyde AICAR-phosphate BN140_RS09655 synthase: asp a [carboxyl-carrier protein dimer]- a long 3' trailer aminopeptidase: aminopeptidase: BN140_RS07220 transposase: rubredoxin: aromatic acid BN140_RS11375 phosphate hept-6-ulosonate hydroxymethyltransferase: reductase: carboxylmethyltransferase: ribonuclease II: )-dimethyltransferase: BN140_RS05745 UvrD: reductoisomerase: phosphatase: amidohydrolase: monophosphatase: DNA glycosylase: ribonuclease II: dehydrogenase: 3-methyl-2- BN140_RS09635 geranylgeranylglycerol- 6 BN140_RS07995 BN140_RS07995 BN140_RS06340 BN140_RS00650 decarboxylase: RS06015 BN140_RS11380 aspartate kinase: dependent enzyme: N -carboxybiotinyl-L-lysine BN140_RS02745 an BN140_RS02700oxidized BN140_RS03810 BN140_RS12005a tRNA BN140_RS03755 [+ 2 isozymes] BN140_RS10260 D-ribofuranose BN140_RS06850 BN140_RS02325 BN140_RS11395 BN140_RS09490 BN140_RS08850 BN140_RS12005 BN140_RS09070 oxobutanoate SAM synthase: phosphate a 5,10- a reduced a ribonucleoside ssDNA/pppN(pN) an N-terminal L- an N-terminal L- AMP BN140_RS06715 2-isopropylmalate L-arginino- N 1 -methyladenine 57 /N 1 - precursor with an N 2 -dimethylguanine 26 met met 5-phosphate (R)-2,3-dihydroxy- a 5-methylcytosine an apyrimidinic a siderophore- RS13475 imidazole glycerol (S)-2-aceto-2- L-citrulline BN140_RS00515 BN140_RS07515 BN140_RS10135 gly ferredoxin [iron- a 5'-phosphooligonucleotide glycolate formate Glu a nucleoside 5'- succinate geranylgeranyltransferase: methylenetetrahydrofolate thioredoxin 58 5'-monophosphate 2 27 hybrid cysteinyl-[protein] threonyl-[protein] myo-inositol serotonin synthase: succinate L-aspartyl- methyladenine in tRNA a 5' extension /N -methylguanine n -1 3-methylpentanoate in DNA site in DNA bound Fe(II) phosphate hydroxybutanoate [+ 2 isozymes] 2-amino-3,7-dideoxy-D- sulfur] cluster monophosphate BN140_RS11370 4-phosphate BN140_RS03765 synthase 2-aceto-2-hydroxy- argininosuccinate argininosuccinate S-adenosylmethionine threo-hept-6-ulosonate 2,3-bis-O- RS03515 [+ 2 isozymes] subunit HisH: butanoate synthase: (2S)-2- lyase: synthetase: (geranylgeranyl)-sn- aspartate- trp 3-dehydroquinate BN140_RS10885 isomeroreductase: BN140_RS04555 BN140_RS04470 a single 3-[(3aS,4S,7aS)-7a-methyl- a 2,3,4-saturated 2 26 a peptide with a 1,2-diacyl- D-ribose 5- BN140_RS09635 isopropylmalate semialdehyde synthase II: glycerol 1-phosphate a [DNA]-3'- a 5'-phospho- + an N -dimethylguanine + a single α nicotinate adenine cobalt- succinate 1,5-dioxo-octahydro-1H coenzyme A NAD FMN NAD(P)H H a (1->4)- -D-glucan agmatine cobalt-precorrin-2 3-phenylpropionitrile sec an alk-2-enal acetoacetate RS06395 imidazole glycerol BN140_RS06850 stranded DNA CTP 1,2-diacyl-sn- hydroxyl [DNA] /N 2 -methylguanine 27 an N-terminal CTP sn-glycerol stranded DNA a tRNA ser dinucleotide phosphate precorrin-5B semialdehyde L-arginino- 3-isopropylmalate dehydrogenase: L-cysteine BN140_RS10145 FMN reductase: phosphate arg met SAH CDP-archaeol exodeoxyribonuclease -inden-4-yl]propanoate acyl-CoA synthetase: glycerol 3-phosphatephosphatidate DNA ligase: tRNA (guanine(10)-N(2) Xaa-L-proline 3-phosphatephosphatidate glycogen- peptidyl-arginine precorrin-2 C(20)- serine-- ribose 5-phosphate cobalt-precorrin- molecular aldehyde acetoacetate (R)-2,3-dihydroxy- succinate dehydratase: BN140_RS05710 2,3-bis-O- peptidase M24: endonuclease: nitrilase: NAD+ synthase: RS12500 synthase biosynthesis II 3-dehydroquinate synthase: VII: BN140_RS01430 BN140_RS04930 BN140_RS02595 BN140_RS00405 branching enzyme: tRNA ligase: isomerase A: 5B (C(1))- 3-methylpentanoate argininosuccinate BN140_RS01575 (geranylgeranyl) cytidylyltransferase: )-dimethyltransferase: BN140_RS07990 cytidylyltransferase: deiminase: methyltransferase: chaperone DnaK: dehydrogenase: decarboxylase: L-aspartate- (tRNA-dependent) BN140_RS01435 a peptide with [+ 5 isozymes] BN140_RS08560 BN140_RS11280 BN140_RS03445 BN140_RS06555 methyltransferase: cyclase subunit: dihydroxy-acid BN140_RS09670 digeranylgeranylglycerophospholipid -sn-glycerol 3-[(3aS,4S,7aS)-7a-methyl-[+ 2 isozymes] BN140_RS09120 BN140_RS03755 a proteinogenic BN140_RS09120 BN140_RS13245 BN140_RS07910 BN140_RS04340 BN140_RS06595 BN140_RS11345 BN140_RS09070 BN140_RS07960 lyase: BN140_RS01580 a single-stranded a ribonucleoside + α BN140_RS08525 semialdehyde 3-phospho- cobalamin-binding 3-dehydroquinase: a CDP-2,3,4-saturated- NMN AMP [DNA] 2 26 an N-terminal a CDP- NAD(P) FMNH a (1,6)- -D-glucosyl- an L-seryl- D-ribulose BN140_RS07935 dehydratase: reductase: BN140_RS07895 1-phosphate 1,5-dioxo-octahydro-1H- an N -dimethylguanine amino acid 2 + RS12675 BN140_RS04555 3-isopropylmalate L-valine biosynthesis oligodeoxyribonucleotide 5'-monophosphate diacylglycerol L-proline diacylglycerol a 5'-phosphooligonucleotide (1,4)-α-glucan N-carbamoylputrescine cobalt-precorrin-3 3-phenylpropanoate [tRNA sec ] NAD cobalt- a 1-alkanal succinate acetone L-serine protein: BN140_RS06070 BN140_RS10175 inden-4-yl]propanoyl-CoA /N 2 -dimethylguanine 27 5-phosphate BN140_RS09585 4-hydroxy- O-phosphoserine- unsaturated reductase: precorrin-6A D-erythro- dehydratase: L-glutamine methionine synthase: RS08555 arg tetrahydrodipicolinate -tRNA ligase: CDP-archaeol BN140_RS07895 AICAR imidazole-glycerol- (S)-3-methyl-2- BN140_RS08575 pyruvate 3-dehydroshikimate biosynthesis I synthase: BN140_RS07200 BN140_RS06755 L-homocysteine S-ribosyl-L-homocysteine oxopentanoate BN140_RS08580 an O-phospho-L- phosphate BN140_RS05720 acetolactate a peptidoglycan a tRNA precursor 2-[(2R,5Z)-2-carboxy- L-fuculose an N-terminal- D-ribulose Cys shikimate shikimate 2,3-bis-O-phytanyl-sn + RNase II poly-A nicotinate adenine phosphoenol a [protein]- imidazoleglycerol- branched chain (2S,4S)-4- synthase: seryl-[tRNA ] icosapentaenoate coenzyme A 4-methylthiazol-5(2H)- HMP-PP carbamoyl a uracil in DNA FMNH NAD Asx D-glucopyranose 2-deoxy-D-ribose cobyrinate 2-isopropylmaleate Glu dimer (S. aureus) with a 5' extension L-ornithine a procollagen 1-phosphate L-methionyl- 2 substrate mRNA a protein a tRNA asp dinucleotide 5-phosphate pyruvate L-glutamine RS06495 amino acid hydroxy-2,3,4,5- BN140_RS05650 dehydrogenase: dehydrogenase: unsaturated -glycerol 1-phosphate serine hydrolase: phosphate fuculose phosphate RS08775 phosphate glutamine O-phospho-L- and a long 3' trailer acyl-CoA synthetase: ylidene]ethyl phosphate thiamine phosphate ornithine uracil-DNA glycyl-[protein]type II methionyl FMN reductase: ribonuclease II: aspartate-- xylose isomerase: cobyrinic acid a,c- chemotaxis aminotransferase: BN140_RS10165 BN140_RS10165 BN140_RS04335 ribonuclease II: peptidase M12: peptidase S41: sugar kinase: uridine kinase: dehydratase: 3-isopropylmalate synthetase: tetrahydrodipicolinate acetolactate seryl-tRNA:Cys- archaetidylserine hypothetical BN140_RS04930 aldolase: glycosylase: BN140_RS09600 BN140_RS12005 BN140_RS01440 NAD+ synthase: pyruvate kinase: di-trans,octa-cis a peptidoglycan BN140_RS12005 synthase: carbamoyltransferase: BN140_RS00345 aminopeptidase: BN140_RS06775 tRNA(Asn) ligase: BN140_RS04590 diamide synthase: protein CheD: BN140_RS04455 BN140_RS03595 4-hydroxy- protein: a tRNA precursor with [+ 3 isozymes] an N-terminal a procollagen BN140_RS09710 BN140_RS12290 [+ 5 isozymes] RNase II BN140_RS06555 BN140_RS01655 BN140_RS12160 L-asparagine dehydratase: BN140_RS07790 synthase: tRNA synthase: shikimate -undecaprenyl D-ala with D,D cross- a nucleoside 5'- BN140_RS00685 BN140_RS09655 BN140_RS07995 BN140_RS06750 [+ 4 isozymes] BN140_RS12135 BN140_RS09390 BN140_RS09670 an apyrimidinic + imidazole acetol- biosynthesis III BN140_RS01575 tetrahydrodipicolinate BN140_RS11375 BN140_RS04180 a 5' extension and icosapentaenoyl-CoA domain of without the N- DHAP (S)-lactaldehyde uracil an N-terminal H NADH FMN AMP substrate with a peptide a peptide an L-aspartyl- 2-deoxy-D-ribose D-ribulose-1,5- α glutamine diphosphate link (S. aureus) monophosphate thiamine phosphate L-citrulline met keto-D-fructose + cob(II)yrinate a [protein]- - ile a short 3' extension terminal domain site in DNA Asx NAD pyruvate RS08145 phosphate (tRNA-dependent) BN140_RS01580 reductase: BN140_RS11380 shikimate kinase: procollagen glycyl-[protein] no poly-A tail [tRNA ] 5-phosphate a,c-diamide bisphosphate L-glutamate RS07950 synthetase: an L-cysteinyl- unsaturated saturated CDP-archaeol long-chain fatty BN140_RS05715 (S)-2-acetolactate Cys BN140_RS12100 histidinol- 3-isopropylmalate BN140_RS11970 [tRNA ] archaetidylethanolamine acid activation asp (S)-2,3,4,5- shikimate phosphate aspartate-- dehydratase: gln ketol-acid peptidyl-tRNA a [LuxE]-S- UDP-N-acetyl-α- tetrahydrodipicolinate dehydrogenase: a long-chain a peptidoglycan 5-amino-4- a 2-deoxy-D- a guanine 26 / 2-methylacetoacetyl- 5,10-methylene- a (1->4)- a glucosylated a (1->4)- a [protein]- transaminase: BN140_RS08575 PRPP a nucleobase sirohydrochlorin Co 2+ O-ureido-L- reduced riboflavin α-D-ribofuranose 5-methylcytosine a nitrile tRNA(Asn) ligase: reductoisomerase: hydrolase: dimer (E. faeciums) scyllo-inosose gln 27 a tRNA precursor (long-chain fatty asp α-D-glucan D-mannosamine glycogenin α-D-glucan BN140_RS08580 LL-diaminopimelate BN140_RS10165 fatty acid imidazolecarboxyamide ribosyl-base guanine in tRNA CoA tetrahydromethanopterin homoserine L-arginine RS07745 BN140_RS02395 L-threonine BN140_RS06750 BN140_RS06850 BN140_RS05940 saturated acyl-CoA serine hydrolase: adenine nucleoside 2- acetyl-CoA formaldehyde- acyl)-L-cysteine sirohydrochlorin glycogen- UDP-N-acetyl-D- glycogen- glycogen- RS12035 an L-aspartyl- aminotransferase: aminotransferase tRNA (guanine(10)-N(2) ribonuclease Z: acyl-CoA argininosuccinate FMN reductase: tRNA-specific peptidyl-arginine biosynthesis (2R,3S)-3- (2R)-2,3- archaetidylserine synthetase: BN140_RS04335 phosphoribosyltransferase: deoxyribosyltransferase: acetyltransferase: activating enzyme: nickelochelatase: mannosamine sugar kinase: nitrilase: L-histidinol- [tRNA Asn ] BN140_RS02345 shikimate 3-phosphate di-trans,octa-cis a peptidoglycan DegT: )-dimethyltransferase: reductase: synthase: branching enzyme: branching enzyme: BN140_RS00405 adenosine branching enzyme: deiminase: isopropylmalate dihydroxy-3- cys BN140_RS04930 BN140_RS06430 BN140_RS12395 BN140_RS03615 dehydrogenase: BN140_RS04590 BN140_RS03445 phosphate BN140_RS02675 BN140_RS12950 BN140_RS08985 BN140_RS03755 BN140_RS09530 BN140_RS10460 BN140_RS09635 BN140_RS11280 BN140_RS11280 [+ 5 isozymes] deaminase: BN140_RS11280 BN140_RS13245 glutamyl-tRNA(Gln) L-glutamate methylbutanoate -undecaprenyl D-ala with D,D cross- a 2-deoxy-D- a single-stranded cobalt- BN140_RS11885 3-isopropylmalate L,L- 3-phosphoshikimate 1- [+ 3 isozymes] 1-amino-1-deoxy- 2 26 mature tRNA acetyl-CoA formaldehyde a [LuxE]- a long-chain α-D-ribose histidinol- L-homoserine a long-chain diphosphate link (E. faecium) AICAR a nucleobase 2-oxoglutaramate an N -methylguanine oligoribonucleotide propanoyl-CoA THMPT canavaninosuccinate a GlgE-glycogen UDP-N-acetyl-α-D- a glycogen BN140_RS04405 a glycogen a [protein]- amidotransferase: biosynthesis I diaminopimelate dihydroxy-acid L-serine biosynthesis ribosyl-base scyllo-inositol L-cysteine fatty aldehyde sirohydrochlorin riboflavin a carboxylate RS10850 dehydrogenase: carboxyvinyltransferase: fatty acyl-CoA /guanine 27 in tRNA 5-phosphate thymine L-citrulline phosphatase: BN140_RS04560 dehydratase: saturated mannosaminuronate RS00310 BN140_RS08565 diaminopimelate BN140_RS10160 BN140_RS11905 BN140_RS04565 BN140_RS09585 3-phospho- archaetidylethanolamine O-phospho- 3-isopropylmalate gln epimerase: histidinol- D-glycerate 5-enolpyruvoyl- aspartyl/glutamyl- hypothetical 3-methyl-2- a DNA containing a poly(ADP- 34 a (1->4)- L-homoserine dehydrogenase: BN140_RS06795 phosphoglycerate shikimate 3-phosphate 7,8-dihydroneopterin a CDP- a long-chain + 3-oxopentanoyl- a cytidine 2+ D-xylopyranose cellulose phosphatase: protein: myo-inositol (R)-mevalonate nicotinate PRPP an apurinic/ NADPH H D-ribose) canavaninosuccinate 2-iminosuccinate DHAP lys precorrin-2 Co superoxide agmatine acetyl-CoA 5-fluorocytosine α pyruvate tRNA(Asn/Gln) BN140_RS01585 oxobutanoate dehydrogenase: 3'-triphosphate diacylglycerol fatty acyl-CoA CoA Ile2 -D-glucan RS04355 BN140_RS12125 threonine meso- crystallin: in tRNA amidotransferase BN140_RS07805 chorismate CDP-alcohol hydroxymethylglutaryl- nicotinate apyrimidinic site acyl-CoA acetyl-CoA argininosuccinate quinolinate sirohydrochlorin superoxide agmatinase: acetyl-CoA xylose isomerase: glycogen- (2S)-2-isopropyl- branched chain BN140_RS02660 6-pyruvoyltetrahydropterin endonuclease III: BN140_RS00365 tRNA(Ile)-lysidine tRNA-specific peptidase M42: hydroxyacid RS04005 synthase: [+ 2 isozymes] diaminopimelate synthase: phosphatidyltransferase: CoA reductase (NADPH) phosphoribosyltransferase: reductase: acetyltransferase: lyase: synthetase: nickelochelatase: dismutase: BN140_RS09480 BN140_RS01440 branching enzyme: subunit C: amino acid 3-phosphooxypyruvate synthase: BN140_RS07235 BN140_RS03660 a poly(ADP- synthase: acetyltransferase: adenosine dehydrogenase: histidinol BN140_RS03455 3-oxosuccinate BN140_RS10170 BN140_RS00480 : BN140_RS12405 BN140_RS05400 BN140_RS10460 BN140_RS12395 BN140_RS04385 BN140_RS03615 BN140_RS03725 BN140_RS05845 BN140_RS11635 Glu diaminopimelate aminotransferase: (6R)-6-pyruvoyl- ADP-D-ribose BN140_RS04555 BN140_RS02215 putrescine urea BN140_RS12395 [+ 4 isozymes] deaminase: BN140_RS11280 BN140_RS10805 PPP a 1-phosphatidyl- [+ 2 isozymes] a long-chain D-ribose) 34 hydrogen histidinol decarboxylase: 3-phosphoserine i 5,6,7,8-tetrahydropterin CMP HMG-CoA NADPH H + NaMN a 3'-terminal a 5'-phospho- propanoyl-CoA acetyl-CoA fumarate L-canavanine quinolinate a lysidine cobalt-precorrin-2 O thr an L-asparaginyl- BN140_RS03595 chorismate 2 D-xylulose BN140_RS04405 starch a cellodextrin RS09025 aminotransferase: 1D-myo-inositol fatty aldehyde in tRNA Ile2 peroxide acetoacetyl-CoA (R)-lactate dehydrogenase: Asn BN140_RS02340 unsaturated sugar [DNA] 5-fluorouracil [tRNA ] BN140_RS07435 Co 2+ RS08795 Co 2+ BN140_RS02480 4-methyl-2- val peptidyl-tRNA oxopentanoate lys 3-phospho- a peptidoglycan dimer (meso a (1->4)- histidinal hydrolase: a [protein]- an organic S-(2-hydroxyacyl) (R)-S- 6,7-dimethyl-8-(1- (indole-3-yl) a (1->4)- 2+ 2+ branched chain L-serine acetoacetyl-CoA H O acetyl-CoA a lipid II UDP-α-D-glucose cellulose riboflavin CTP starch starch α-amylose carbonic acid Mg Mg RS07855 BN140_RS05940 2 -diaminopimelate containing) phosphate acetyl-CoA a [glutamine- α-D-glucan roseoflavin α-D-glucan RS11810 ATP L-cysteine hydroperoxide glutathione lactoylglutathione D-ribityl)lumazine ATP acetonitrile FMN ATP Co 2+ Co 2+ histidinol amino acid serine hydrolase: serine hydrolase: glycosyl transferase: alpha-amlyase: MBL fold 5'-phosphate alpha-amlyase: carbonic phosphoserine hydroxymethylglutaryl-CoA phosphotransacetylase: synthetase]-L-tyrosine peroxiredoxin: MBL fold riboflavin synthase: riboflavin kinase: glycogen- dehydrogenase: aminotransferase: BN140_RS04335 BN140_RS04335 BN140_RS03730 BN140_RS11270 hydrolase: BN140_RS11270 nitrilase: alpha-amlyase: anhydrase: alpha-amlyase: asn phosphatase: synthase: BN140_RS12390 BN140_RS04445 adenylyltransferase: BN140_RS01845 hydrolase: BN140_RS07440 BN140_RS12380 FAD synthase: branching enzyme: FAD synthase: BN140_RS02480 BN140_RS03595 a N-acetylglucosamine--N- a peptidoglycan with a (1->4)- BN140_RS11270 BN140_RS11270 Mg 2+ Mg 2+ BN140_RS11035 UDP cellulose BN140_RS10735 an intra- maltohexaose BN140_RS12255 BN140_RS12255 BN140_RS11925 glucose maltose BN140_RS03445 BN140_RS11280 BN140_RS09590 BN140_RS11925 RS11760 lys RS03465 lys HMG-CoA D-ala acetylmuramyl-(tetrapeptide) D-ala D,D cross-links (meso- a [glutamine synthetase]-O an alcohol α-D-glucan riboflavin ARP CDP FMN roseoflavin adenine 2+ 2+ acetyl phosphate protein disulfide a 2-hydroxy a large- a (1->4)- Co Co 4 glutathione (R)-lactate glutathione CO H O FAD pyrophosphoryl-undecaprenol diaminopimelate containing) 2 2 his leu ser -(5'-adenylyl)-L-tyrosine carboxylate dinucleotide (indol-3-yl)acetate branched glucan amylopectin α-D-glucan

RS06225 Co 2+ RS12145 Co 2+ glycine betaine an amino lys gly acid Glu a sulfonate maltotetraose Co 2+ RS05970 Co 2+ a polar an amino an amino asp a hydroxamate a C4- a quaternary cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA phosphate phosphate phosphate phosphate maltotriose a siderophore- RS07370 amino acid 3+ tungstate tungstate acid acid molybdate molybdate a macrolide a macrolide a macrolide daunorubicin a nucleotide [+ 4 more] Fe dicarboxylate amine a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA phosphate maltose bound Fe(III) predicted predicted ABC predicted ABC transporter ABC RS09440 RS10855 RS02635 GlnQ RS08055 RS12190 RS07850 RS05780 RS12965 RS09420 RS03410 RS11675 RS12815 RS11590 RS04330 RS00085 RS09075 RS12270 RS08805 RS07685 RS02380 RS08035 RS12530 RS07470 RS04145 RS06205 RS11030 RS08220 RS09225 RS09020 RS01330 RS05950 RS08270 RS02070 RS01670 RS07875 RS05805 RS05680 GlnQ RS09470 RS13030 RS02505 RS05635 RS09535 transporter RS02825 RS02515 RS00665 RS02275 RS07005 RS07480 RS00605 RS11350 RS09630 RS09460 RS12695 RS02495 RS08030 RS10880 RS06765 RS10470 RS04930 RS11575 RS00185 RS06510 RS06515 RS12045 RS10895 RS00775 RS05045 RS01830 RS08080 RS09730 RS11405 RS12445 RS04895 RS10905 RS11075 RS01020 RS12710 RS11930 RS11420 RS08845 RS10615 RS04980 RS08505 RS12870 RS03435 RS08760 RS12460 RS12030 RS13190 RS07185 RS08910 RS05925 RS07420 RS11245 RS07965 RS08925 RS03440 RS11365 RS02565 RS02690 RS00325 RS05175 RS12550 RS06190 RS12415 RS09195 RS12140 RS02535 of glycine/ transporter of an glycine of a sulfonate amino acid betaine maltotetraose lys a polar a quaternary cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate a siderophore- molybdate maltotriose Glu amino acid amine a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid bound Fe(III) asp maltose [+ 4 more]

glycine betaine a hydroxamate a C4- daunorubicin a sulfonate tungstate tungstate an amino an amino an amino molybdate a macrolide a macrolide a macrolide a nucleotide phosphate phosphate phosphate phosphate 3+ dicarboxylate gly Fe acid acid acid phosphate This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.