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This section is published monthly to inform the practicing physician about new drug products and medical equipment made avail- able on the market. It is a reference section prepared by THE JOURNAL from descriptive material furnished by ethical manufac- turers. The American Osteopathic Association does not necessarily advocate the use of these products nor disapprove any product not included. The purpose of the section is to provide trustworthy information in a convenient form.

Product News

RHULIHIST insect bites and other minor skin irritations. Chemistry • Each 4-ounce pack- age contains 1 per cent tripelenna- Contraindications • Rhulihist is mine hydrochloride, 3 per cent not to be used in the eves: nor is it calamine, 1 per cent zirconium ox- for prolonged use. If the condition ide, 1 per cent , 0.1 per persists or if a rash or irritation cent , 0.1 per cent menthol, develops, discontinue use and con- 0.08 per cent methylparaben, and sult a physician. 0.02 per cent propylparaben. Dosage schedule • Rhulihist is to be applied to the affected area Pharmacodynamics • Rhulihist two to three times daily and at is an - lotion de- 1/1011H/311 bedtime—or as needed. kfiCi. Gf AN ESN( signed to provide soothing relief of the temporary leer Or the minor itching and pain. It dries (thingI and discomfort Of How supplied • It is available in vy AND OAK promptly and leaves a protective POISONING. 4-ounce bottles. NONPOISONOUS INSECT BITES film over the affected skin. and other minor skin irritations Manufacturer • Lederle Labora- Indications • This preparation is tories, Division of American Cyana- for use in cases of ivy and oak poi- mid Company, Pearl River, New soning as well as for nonpoisonous York.

1089/79 JOURNAL A.O.A., VOL. 62, AUGUST 1963 KETOSTIX® tone and acetoacetic acid, reacting with as little as 5 to 10 mg. per 100 Description • The new Ketostix ml. of acetoacetic acid in urine, is a 15 second, sodium nitroprus- serum, and plasma. side strip test for the detection of ketone bodies in urine, serum, or How supplied • New Ketostix is plasma. It has been designed to available in glass bottles of 50 and offer new conveniences over older 100 strips. methods of testing, such as speed, sensitivity, specificity, and reading ease. A longer impregnated strip Manufacturer • Ames Company, offers better color diffusion in the Inc., 819 McNaughton Avenue, Elk- test area. It is specific for both ace- hart, Indiana.

1090/80 SANBORN MODEL 780 at the onset of bradycardia, tachy- An audible alarm, supplied by VISO-MONITOR AND cardia, pulse loss, or pulse arrest; the Model 780-800 Remote Indica- SANBORN MODEL 780-800 while the integral pacemaker may tor, is optional. It has visual indi- REMOTE INDICATOR be set for automatic operation in cator lights and a heart rate meter the event of cardiac arrest. The identical to those on the main unit. unit supplies both internal and ex- Each QRS complex produces a Description • This new bedside ternal pacemaking voltages. "beep," and any distress condition cardiac monitoring system (Model The illuminated, colored win- triggers a continuous tone, each 780) is compact, completely transis- dows on the front panel give visual adjustable for the desired volume. torized, and designed for depend- warning of eight possible occur- Plug-in jacks are provided on the able observation of the cardiac or rences: bradycardia, tachycardia, rear of the Viso-Monitor to facili- postoperative patient before, dur- pulse loss, pulse arrest, instrument tate its connection to a hospital call ing, or after surgery—in intensive power, pacing circuit operation, system, an oscilloscope, or to the care units, in recovery rooms, or in QRS complex, and inoperative in- Remote Indicator unit. the operating room. Both the built- strument condition. A meter in electrocardiograph and the in- equipped with adjustable upper tegral pacemaker can be activated and lower limit settings continuous- manually. However, the electro- ly displays the heart rate. The Manufacturer • Sanborn Com- cardiograph can also be set to re- front panel carries push-button and pany, Medical Division, 175 Wy- cord automatically for 10 seconds thumb-wheel controls for all func- man Street, Waltham 54, Massa- at either pre-selected intervals or tions. chusetts.

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DUPHASTON® result in resumption of normal is indicated in cases of threatened menstruation. Where infertility is abortion, habitual abortion, en- Chemistry • Duphaston ( dydro- due to inadequate luteal formation, dometriosis, dysmenorrhea, infer- gesterone—formerly isopregnen- Duphaston may be used to pro- tility due to inadequate corpus one) is the 6-dehydro stereochem- mote an adequate progestational luteum function, either primary or ical isomer of , endometrium and enhance the secondary amenorrhea, menorrhag- chemically identified in its pure prospects for conception. Since it ic disorders, and premenstrual ten- crystalline form as 9-beta, 10-al- has no thermogenic activity, rec- sion. It may also be used as a preg- pha-pregna-4, 6-diene-3, 20-dione. ords of basal body temperature nancy test. may be safely relied upon to indi- Pharmacodynamics • This retro- cate the most favorable time for Contraindications • There are no isomer of progesterone induces conception. known contraindications to the use bleeding in amenorrheic patients of Duphaston. who have adequate estrogen levels: Toxicology • The few mild gas- estrogen priming is required in trointestinal complaints (nausea, Dosage schedule • The usual those who have not. It promotes diarrhea, and constipation) that dosage is between 10 and 20 mg. the development of normal secre- have been reported have not neces- per day, according to the condi- tory endometrium rather than pseu- sitated withdrawal of the drug. The tion treated, except in cases of en- dodecidual change and frequently occasional occurrences of spotting dometriosis, and habitual abortion, results in the establishment of or break-through bleeding usually where daily dosage may exceed normal, spontaneous menstruation indicate a dosage level too low for 20 mg. after a few cycles of treatment. the particular patient: an increase Duphaston is usually effective in of from 5 to 10 mg. per day should How supplied • Duphaston is suppressing abnormal bleeding as- prevent this type of bleeding. available in either 5 or 10 mg. sociated with the various forms of There have been no endocrinologic white scored tablets, packaged menorrhagia, including menopausal side effects, such as masculinizing twenty to a bottle. bleeding, but it does not suppress of a female fetus or virilizing of normal menstruation. A few days the patient, nor has any cortico- Manufacturer • Philips Roxane after cessation of the , drug, with- activity been reported. Laboratories, Division of Philips drawal bleeding occurs, and suc- Roxane, Inc., 330 Oak Street, Co- cessive courses of Duphaston often Indications • Duphaston therapy lumbus 16, Ohio.

1092/82 ANDER CID® heartburn of pregnancy, hiatus hernia, or esophagitis. They may Chemistry • Each therapeutic be used by acid hypersecretors unit is one oven-baked Andercid prior to seasons of peak ulcer in- wafer which contains 500 mg. com- cidence or with ulcerogenic medi- bined carbonate and mag- cation. nesium trisilicate (in an 8:5 ratio) with added milk solids. Contraindications • There are no known contraindications or pre- cautions. Pharmacodynamics • The com- bined antacids afford effective mod- Dosage schedule • One or two eration of gastric acidity, while the wafers for immediate relief, be- palatable form—free of the gritti- tween meals, at bedtime, or as ness or chalkiness usually associated needed. They may be followed by with antacids—helps insure patient milk or water. acceptance for intermittent, long- term, or prophylactic therapy. The How supplied • Andercid antacid combination of calcium carbonate wafers, contained in pocket-sized, and magnesium trisilicate avoids moisture-proof sealed pouches, are either constipation or laxation. available in cellophane-wrapped boxes of 60. Indications • Andercid antacid wafers may be specified whenever Manufacturer • Anderson Lab- an antacid is indicated, especially oratories, 625 Cleveland Avenue, in cases of peptic ulcer, gastritis, Columbus 16, Ohio.

JOURNAL A.O.A., VOL. 62, AUGUST 1963 1093/83 DISPOSABLE blood-fill level. The filling tech- SEDIMENTATION niques, the anticoagulant used, and RATE SYSTEM the "normals" are the same as for the Wintrobe tube. Description • A disposable sedi- The Sedirak sedimentation tube mentation rate system consisting of rack is a reusable rack designed to disposable sedimentation tubes hold eight Seditube units in an ex- (Seditube) and a plastic tube rack act vertical position. A millimeter (Sedirak) has recently been intro- scale is provided for each of the duced to aid the technician in elimi- eight positions, allowing direct nating the time-consuming after- readings of the amount of settling care and cleaning usually con- of red blood cells. A spirit level nected with this procedure. and adjusting screws permit level- Comparable to the reusable Win- ing of the rack to assure the vertical trobe tube in physical design and orientation of the tubes. This is the characteristics, Seditube units differ only disposable sedimentation rate in that they are disposable and do system with a rack which can be not carry a scale ( Sedirak supplies leveled to assure absolute accuracy. the scale). This disposable tube— packaged in 50s has a single cir- Manufacturer • Becton, Dickin- cular fill line 100 mm. from the son and Company, Rutherford, New bottom of its bore to indicate the Jersey.

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