Top 25 Excluded Compounded Drugs* and Commercially Available Alternatives

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Top 25 Excluded Compounded Drugs* and Commercially Available Alternatives Compound Ingredient Indication Commercially Available Alternative BACLOFEN POWDER Topical pain baclofen oral tablet, solution for intrathecal injection BUPIVACAINE HCL Topical pain bupivacaine solution for injection POWDER CYCLOBENZAPRINE HCL cyclobenzaprine tablets, extended-release capsules, tablet in combo pack POWDER Topical pain with topical gel containing capsicum, menthol and other ingredients (Comfort Pac with cyclobenzaprine tablet) DICLOFENAC SODIUM Topical pain diclofenac tablets (extended-release, delayed-release), 1.5% topical solution, POWDER 0.1% ophthalmic solution, 3% topical gel ETHOXY DIGLYCOL LIQUID Solvent solvent for compounding FLURBIPROFEN POWDER Topical pain flurbiprofen oral tablets, ophthalmic solution FLUTICASONE fluticasone propionate 0.05% topical cream and lotion; PROPIONATE POWDER Topical pain fluticasone propionate 0.005% topical ointment GABAPENTIN POWDER Topical pain gabapentin capsules, tablets and oral solution KETAMINE HCL POWDER Topical pain ketamine solution for injection KETOPROFEN Topical pain ketoprofen capsules and extended-release capsules MICRONIZED POWDER LEVOCETIRIZINE Scar gel levocetirizine tablets, oral solution DIHYDROCHL POWDER LIPODERM BASE Vehicle (base) vehicle base for compounding LIPO-MAX CREAM Vehicle (base) vehicle base for compounding LIPOPEN PLUS CREAM Vehicle (base) vehicle base for compounding LIPOPEN ULTRA CREAM Vehicle (base) vehicle base for compounding BASE MELOXICAM POWDER Topical pain meloxicam oral tablet, oral suspension, tablet in combo pack with topical gel containing capsicum, menthol and other ingredients (Comfort Pac with meloxicam tablet) MOMETASONE FUROATE Topical pain mometasone furoate 0.1% topical cream, lotion and ointment POWDER NABUMETONE Topical pain nabumetone tablets MICRONIZED POWDER PRACASIL TM-PLUS GEL Vehicle (base) vehicle base for compounding PRILOCAINE HCL POWDER Topical pain Citanest Plain 4% dental solution for injection (dental solution also available with epinephrine), lidocaine prilocaine 2.5% -2.5% cream RESVERATROL Anti- dietary supplement available in over-the-counter (OTC) formulations; not an Inflammatory approved drug SPIRA-WASH GEL Vehicle (base) vehicle base for compounding TRAMADOL HCL POWDER Topical pain Tramadol tablets, extended-release tablets, and in combination with acetaminophen VERSAPRO CREAM BASE Vehicle (base) vehicle base for compounding VERSATILE CREAM BASE Vehicle (base) vehicle base for compounding *The FDA defines a compounded drug as one that requires a licensed pharmacist to combine, mix or alter the ingredients of a medication when filling a prescription. Compounded drugs, unlike FDA-approved medications, often lack the rigorous clinical studies to validate safety and effectiveness. .

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Using Rheology Measurement As a Potentially Predictive Tool for Solder Paste Transfer Efficiency and Print Volume Consistency
USING RHEOLOGY MEASUREMENT AS A POTENTIALLY PREDICTIVE TOOL FOR SOLDER PASTE TRANSFER EFFICIENCY AND PRINT VOLUME CONSISTENCY Mitch Holtzer, Karen Tellefsen and Westin Bent Alpha Assembly Solutions South Plainfield, NJ, USA [email protected] ABSTRACT Commercially available solder pastes use an upper and Industry standards such as J-STD-005 and JIS Z 3284-1994 lower limit for viscosity. Generally, this viscosity is call for the use of viscosity measurement(s) as a quality measured at one shear rate, typically the shear associated assurance test method for solder paste. Almost all solder with a spiral viscometer rotating at 10 revolutions per paste produced and sold use a viscosity range at a single minute (RPM). If the powder contained in solder paste is shear rate as part of the pass fail criteria for shipment and dissolved by the acid activator in the solder paste flux, the customer acceptance respectively. viscosity of the solder paste will quickly increase. If the viscosity increases more than 20 to 30% above the upper As had been reported many times, an estimated 80% of the limit of the specification, poor printing results will be highly defects associated with the surface mount technology likely. The solder paste will not roll evenly over the stencil process involve defects created during the printing process. and apertures in the stencil will remain unfilled, causing Viscosity at a single shear rate could predict a fatal flaw in skips in the paste printing pattern. the printability of a solder paste sample. However, false positive single shear rate viscosity readings are not The purpose of the study was to determine if there is a unknown.
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Orally Inhaled & Nasal Drug Products
ORALLY INHALED & NASAL DRUG PRODUCTS: INNOVATIONS FROM MAJOR DELIVERY SYSTEM DEVELOPERS www.ondrugdelivery.com 00349_GF_OnDrugDelivery349_GF_OnDrugDelivery PulmonaryPulmonary NasalNasal NovemberNovember 2010.indd2010.indd 1 330/11/100/11/10 111:32:331:32:33 “Orally Inhaled & Nasal Drug Products: Innovations from Major Delivery CONTENTS System Developers” This edition is one in the ONdrugDelivery series of pub- Innovation in Drug Delivery by Inhalation lications from Frederick Furness Publishing. Each issue focuses on a specific topic within the field of drug deliv- Andrea Leone-Bay, Vice-President, Pharmaceutical ery, and is supported by industry leaders in that field. Development, Dr Robert Baughman, Vice-President, Clinical Pharmacology & Bioanalytics, Mr Chad EDITORIAL CALENDAR 2011: Smutney, Senior Director, Device Technology, February: Prefilled Syringes Mr Joseph Kocinsky, Senior Vice-President, March: Oral Drug Delivery & Advanced Excipients Pharmaceutical Technology Development April: Pulmonary & Nasal Drug Delivery (OINDP) MannKind Corporation 4-7 May: Injectable Drug Delivery (Devices Focus) June: Injectable Drug Delivery (Formulations Focus) Current Innovations in Dry Powder Inhalers September: Prefilled Syringes Richard Sitz, Technical Manager, DPI Technology October: Oral Drug Delivery Platform Leader November: Pulmonary & Nasal Drug Delivery (OINDP) 3M Drug Delivery Systems 10-12 December: Delivering Biologics (Proteins, Peptides & Nucleotides) Pulmonary Delivery & Dry-Powder Inhalers: SUBSCRIPTIONS: Advances in Hard-Capsule
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An Introduction to Fast Dissolving Oral Thin Film Drug Delivery Systems: a Review
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Excluded Drug List
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Mometasone Powder Rationale for Inclusion In
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Direct-Write Fabrication of Pb(Nb,Zr,Ti)O3 Devices: Influence of Paste Rheology on Print Morphology and Component Properties
journal J. Am. Ceram. Soc., 84 [11] 2462–68 (2001) Direct-Write Fabrication of Pb(Nb,Zr,Ti)O3 Devices: Influence of Paste Rheology on Print Morphology and Component Properties Sherry L. Morissette*,† and Jennifer A. Lewis* Department of Materials Science and Engineering, University of Illinois, Urbana, Illinois 61801 Paul G. Clem,* Joseph Cesarano III,* and Duane B. Dimos* Sandia National Laboratories, Albuquerque, New Mexico 87185 Lead niobium zirconate titanate (PNZT) pastes with tailored required before deposition of additional layers, this direct-write rheological properties have been developed for direct-write approach yields significant advantages over the conventional fabrication of thick-film capacitor elements in highly inte- method for producing multilayer devices, such as those based on grated, multifunctional electroceramic devices. Such pastes lamination of tape-cast layers with screen-printed elements, in- exhibited pseudoplastic behavior with a low shear apparent cluding the ability to modify patterned designs on-line during .viscosity of roughly 1 ؋ 106 cP. On aging, the degree of shear printing and to incorporate multiple materials in individual layers thinning and the low shear apparent viscosity decreased. The rheological requirements of thick film pastes for micropen Pastes prepared from as-received powders attained printable, printing and screen printing are nearly identical.7–9,11–17 Hence, -steady-state viscosities of ϳ2 ؋ 105 cP after 50 days of aging. commercially available screen printing pastes (e.g., silver–palla In contrast, pastes prepared from dispersant-coated powders dium conductor, ruthenium oxide resistor, and dielectric pastes) showed no measurable rheological changes after 1 day of can be readily utilized in this direct-write approach.
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