Maria João Correia Pinto Carvalho De Matos

Maria João Correia Pinto Carvalho de Matos

RESEARCH INTERESTS: Our research programme is at the interfaces of Chemistry and Pharmacology. My research experience it is focused on the Medicinal Chemistry area particularly in the early stages of the process, which involves the design, synthesis and biological screening of new compounds based on heterocyclic scaffolds.

EXPERIENCE February, 2014 - Postdoctoral Researcher with Professor Fernanda Borges, Department of Chemistry Currently and Biochemistry, University of Porto; collaboration with the Department of Organic Chemistry, University of Santiago de Compostela January, 2015 - Editorial Board Member of the EC Chemistry journal (E-Cronicon Open Access) Currently July, 2014 - Editorial Board Member of the Journal of Bioorganic & Organic Chemistry (Austin Currently publishing group) January, 2014 Research invited stay with Professor Claudio Olea, Department of Inorganic and Analytic Chemistry, University of Santiago de Chile 2011-2013 Participation in POD (professor of practical lessons) Pharmaceutical and Organic Chemistry, University of Santiago de Compostela 2011-2012 Current Topics in Medicinal Chemistry Guest Editor 2010-2013 Graduate Research Assistant with Professor Fernanda Borges, Department of Chemistry and Biochemistry, University of Porto, and Professor Eugenio Uriarte, Department of Organic Chemistry, University of Santiago de Compostela 2007-2010 Graduate Research Assistant with Professor Gianni Podda, Department of Pharmaceutical and Chemical Technology, University of Cagliari, and Professor Lourdes Santana, Department of Organic Chemistry, University of Santiago de Compostela 2005-2006 Undergraduate Research Assistant (Erasmus and Leonardo Da Vinci exchange programs) with Professor Eugenio Uriarte, Department of Organic Chemistry, University of Santiago de Compostela

EDUCATION 2010-2013 Ph.D., Organic Chemistry, Cum Laude, Department of Organic Chemistry, University of Santiago de Compostela 2011-2012 Course “Innovación 360º” from Akademia (Fundación de la Innovación Bankinter) 2007-2010 Ph.D., Chemical and Pharmaceutical Science and Technology, Cum Laude, Department of Pharmaceutical and Chemical Technology, University of Cagliari

2006-2008 M.S., Organic Chemistry, Department of Organic Chemistry, University of Santiago de Compostela (classification 10/10) 1999-2006 B.A., Pharmaceutical Sciences, Faculty of Pharmacy, University of Porto (classification 2,78/3)

AWARDS AND FELLOWSHIPS

• Postdoctoral Fellowship (SFRH/BPD/95345/2013), 2014-2018 • SEQT Grants to attend XI Jornadas de la SEQT and EFMC-ISMC, 2014 • RSEQ Grant to attend SISOC X, 2014 • Ph.D. Fellowship (SFRH/BD/61262/2009), 2010-2013 • Academy of Sciences of Cuba Award, 2011 • RSEQ Grant to attend VIII Simposio RSEQ Sigma-Aldrich, 2011 • SEQT Grant to attend XVI Congreso de la SEQT, 2011 • USC Grant to attend Frontiers in Medicinal Chemistry, 2011 • Delegation of CITMA (Camagüey – Cuba) Award, 2010 • Mobility Scholarship: obtention of European Doctorate (TME2011-00615), 2010 • USC Grant to attend EFMC-ISMC, 2010 • SEQT Grant to attend IX Jornadas de la SEQT, 2010 • EFMC Grant to attend ESMEC, 2010 • SEQT Grant to attend Frontiers in Medicinal Chemistry and the summer school, 2009 • SEQT Grant to attend VIII Jornadas de la SEQT, 2008 • Xunta de Galicia Grant to attend First Iberic Meeting on Medicinal Chemistry, 2007 • MIUR Ph.D. Fellowship to attend Scuola Di Dottorato in Scienze e Tecnologie Chimiche e Farmaceutiche, 2007-2010 • Fellowship (DCT2006-00551-B) for mobility, 2007 • Socrates/Leonardo Fellowship, 2006 • Erasmus Fellowship, 2005/2006

PHD’S THESIS COMMITTEE MEMBER María González Pérez. 2014 – University of Vigo, Spain. Laura Aramburu Villar. 2014 – University of Salamanca, Spain.

TRAINING AND TEACHING EXPERIENCE Participation in POD (professor of practical lessons) (2011/2012 and 2012/2013). Co-orientation of Ph.D., Master and ERASMUS students. Orientation of graduate research projects, undergraduate research projects and TAD (undergraduate research projects)

REFEREE/REVIEWER Referee of more than 20 scientific journals and international evaluation committees.

SCIENTIFIC PUBLICATIONS IN INTERNATIONAL JOURNALS, BOOK CHAPTERS AND PATENTS

1 Patent: “Use of 6-substituted 3-phenylcoumarins as selective MAO-B inhibitors for treating neurodegenerative diseases and obesity and preparation of new derivatives”, Number: WO2010086484 A1. Priority country: Spain. Date: 05/08/2010. Titular entity: USC.

3 Book chapters

50 Publications in international scientific journals, being the 10 most relevant:

1. Gaspar, A.; Milhazes, N.; Santana, L.; Uriarte, E.; Borges, F.; Matos, M.J.* – Current Topics in Medicinal Chemistry 2015, 15(5), 432-445, doi: 10.2174/1568026614666141229124141. 2. Matos, M.J.*; Vazquez-Rodriguez, S.; Uriarte, E.; Santana, L. – Expert Opinion on Therapeutic Patents 2014, 25(3), 1-16. doi:10.1517/13543776.2014.995627. 3. Matos, M.J.*; Vilar, S.; Kachler, S.; Fonseca, A.; Santana, L.; Uriarte, E.; Borges, F.; Tatonetti, N.P.; Klotz, K.-N. – ChemMedChem 2014, 9, 2245-2253 (paper selected as back cover of the issue). doi: 10.1002/cmdc.201402205. 4. Matos, M.J.*; Vilar, S.; García-Morales, V.; Tatonetti, N.P.; Uriarte, E.; Santana, L.; Viña, D. – ChemMedChem 2014, 9, 1488-1500. doi: 10.1002/cmdc.201300533. 5. Matos, M.J.*; Janeiro, P.; González Franco, R.M.; Vilar, S.; Tatonetti, N.P.; Santana, L.; Uriarte, E.; Borges, F.; Fontanela, J.A.; Viña, D. – Future Medicinal Chemistry 2014, 6(4), 371-383. doi: 10.4155/fmc.14.9. 6. Gaspar, A.; Matos, M.J.; Garrido, J.; Uriarte, E.; Borges, F.* – Chemical Reviews 2014, 114 (9), 4960-4992. doi: 10.1021/cr400265z. 7. Pérez-Cruz, F.; Vazquez-Rodriguez, S.*; Matos, M.J.; Herrera-Morales, A.; Villamena, F.; Das, A.; Gopalakrishnan, B.; Olea-Azar, C.; Santana, L.; Uriarte, E. – Journal of Medicinal Chemistry 2013, 56, 6136-6145. DOI: 10.1021/jm400546y. 8. Matos, M.J.*; Pérez-Cruz, F.; Vazquez-Rodriguez, S.; Uriarte, E.; Santana, L.; Borges, F.; Olea-Azar, C. – Bioorganic & Medicinal Chemistry 2013, 21, 3900-3906. DOI: 10.1016/j.bmc.2013.04.015. 9. Matos, M.J.*; Vilar, S.; Gonzalez-Franco, R.M.; Uriarte, E.; Santana, L.; Friedman, C.; Tatonetti, N.P.; Viña, D.; Fontenla, J.A. – European Journal of Medicinal Chemistry 2013, 63, 151-161. DOI: 10.1016/j.ejmech.2013.02.009. 10. Matos, M.J.*; Terán, C.; Pérez-Castillo, Y.; Uriarte, E.; Santana, L.; Viña, D.* – Journal of Medicinal Chemistry 2011, 54, 7127-7137. dx.doi.org/10.1021/jm200716y.

29 Proceedings

PARTICIPATION IN SEMINARS, CONFERENCES, COURSES, WORKSHOPS AND SCIENTIFIC OUTREACH EVENTS

21 Oral communications in national and international conferences, including: 1. 22nd Young Research Fellow Meeting 2015, Paris - Biocitech, Franche, 4-6 February, 2015. 2. 10th Spanish-Italian Symposium on organic chemistry (SISOC-X) – Florence, Italy, 17-20 July, 2014. 3. VII Simposio Internacional de Quimica de Productos Naturales y sus Aplicaciones – Chile, 5-8 November – plenary lecture by invitation, 2012.

70 poster presentations in national and international conferences