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Selected Abstracts of the 14Th International Workshop on Neonatology

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Selected Abstracts of the 14Th International Workshop on Neonatology www.jpnim.com Open Access eISSN: 2281-0692 Journal of Pediatric and Neonatal Individualized Medicine 2018;7(2):e070237 doi: 10.7363/070237 Published online: 2018 Oct 23 Abstracts Selected Abstracts of the 14th International Workshop on Neonatology THE REVOLUTION OF MICROBIOMICS NUTRITION, BACTERIA AND PROBIOTICS IN PERINATAL AND PEDIATRIC HEALTH CAGLIARI (ITALY) • OCTOBER 24TH-27TH, 2018 The Workshop has been organized with the patronage of the Italian Society of Neonatology (SIN), the Italian DOHaD (Developmental Origins of Health and Disease) Society (SI-DOHaD), the Italian Society of Clinical Biochemistry and Clinical Molecular Biology (SIBioC), the Union of European Neonatal and Perinatal Societies (UENPS), the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC), the Union of Middle-Eastern and Mediterranean Pediatric Societies (UMEMPS), the European Association of Perinatal Medicine (EAPM), the Italian-Romanian Pediatric Society (IRPS) and the Italian- Arabian Pediatric Society (IAPS). WORKSHOP’S PRESIDENTS Vassilios Fanos (Cagliari, Italy), Egbert Herting (Lübeck, Germany), Moshe Hod (Tel Aviv, Israel), Manuel Sánchez-Luna (Madrid, Spain), Michele Mussap (Cagliari, Italy), Sergio Bernardini (Rome, Italy), Antonio Ragusa (Massa Carrara, Italy), Ana Maria Ciubara (Galati, Romania), Gavino Faa (Cagliari, Italy), Giuseppe Floris (Leuven, Belgium) WORKSHOP’S HONORARY COMMITTEE S. Bernardini (Rome, Italy), P. Biban (Verona, Italy), M. Bruscagnin (Turin, Italy), G. Buonocore (Siena, Italy), P. Calò (Cagliari, Italy), A.M. Ciubara (Galati, Romania), G. Corsello (Palermo, Italy), G.C. Di Renzo (Perugia, Italy), C. Fabris (Turin, Italy), V. Fanos (Cagliari, Italy), G. Finco (Cagliari, Italy), M. Hod (Tel Aviv, Israel), V. Modica (Byblos, Lebanon), G. Monni (Cagliari, Italy), F. Mosca (Milan, Italy), R. Mura (Cagliari, Italy), G. Perricone (Palermo, Italy), D. Pisano (Cagliari, Italy), C. Romagnoli (Rome, Italy), M. Sánchez-Luna (Madrid, Spain), S. Vendemmia (Aversa, Italy), F. Vicariotto (Milan, Italy), P. Vezzoli (Cagliari, Italy) WORKSHOP’S INTERNATIONAL FACULTY E. Bertino (Turin, Italy), G. Buonocore (Siena, Italy), L. Cataldi (Rome, Italy), G. Corsello (Palermo, Italy), C. Dani (Florence, Italy), G.C. Di Renzo (Perugia, Italy), G. Faa (Cagliari, Italy), V. Fanos (Cagliari, Italy), F. Ferrari (Modena, Italy), E. Herting (Lübeck, Germany), S. Iacobelli (Saint Pierre, France), P. Paolillo (Rome, Italy), A. Ragusa (Massa Carrara, Italy), F. Velardi (Rome, Italy) OTHER PRESIDENTS Giovanni Ottonello (Cagliari, Italy), Denis Pisano (Cagliari, Italy), Melania Puddu (Cagliari, Italy) 1/66 www.jpnim.com Open Access Journal of Pediatric and Neonatal Individualized Medicine • vol. 7 • n. 2 • 2018 How to cite surgeon in 82% of the cases. 17% initially adopt a conservative attitude; 75% apply creams with a [Abstract’s authors]. [Abstract’s title]. In: Selected Abstracts recurrence rate of 15.9%. This rate is highest in of the 14th International Workshop on Neonatology; Cagliari the case of a manual separation (21%). (Italy); October 24-27, 2018. J Pediatr Neonat Individual Med. CONCLUSION 2018;7(2):e070237. doi: 10.7363/070237. The coalescence of the labia minora is a common, benign, commonly asymptomatic, poorly known ABS 1 and underestimated condition in Lebanon with an incidence of 0.12% per year. 1/5 of pediatricians AWARENESS ABOUT LABIA MINORA FUSION do not examine the genital area of girls mainly AMONG LEBANESE PEDIATRICIANS male pediatricians. 75% of the pediatricians use estrogenic creams or corticosteroids, and 17% are M. Amm1, M.C. Fadous Khalife1, V. Modica1, H. conservative. The clinical presentation is similar to Feghali1, J. Mardini1, M. AlOjaimi2 that found in the literature. 1Holy Spirit University of Kaslik, Kaslik, UH-Notre Dame Des Secours, Jbeil, ABS 2 Lebanon 2Balamand University, Koura, Lebanon SUCCESSFUL CONSERVATIVE MANAGEMENT OF A GIANT UNILATERAL PNEUMATOCELE IN INTRODUCTION AN EXTREMELY LOW BIRTH WEIGHT INFANT Our three main objectives are to assess knowledge about the coalescence of labial minora among F. Bissolo, C. Forcellini, R. Beghini, S. Lauriola, Lebanese pediatricians, evaluate the number M. Ventola, B. Ficial, E. Bonafiglia, L. Chini, L. of pediatricians who perform a systematic Pecoraro, I. Sibona, R. Frassoldati, P. Biban gynecological examination in young girls and describe the pediatric gynecologic pathology in Neonatal Intensive Care Unit, Department of Pediatrics and Neonatal Lebanon including a literature review. Critical Care, Verona University Hospital, Verona, Italy MATERIAL AND METHODS This is a cross-sectional descriptive study conducted INTRODUCTION in 2014 through a questionnaire that was answered Pneumatocele is an air-filled, thin wall cavity within by 117 pediatricians practicing in the different the lung parenchyma. It may be a consequence of Lebanese regions, and the data were analyzed on protracted mechanical ventilation or a complication “Microsoft® Excel® 2013” in order to meet the of S. aureus pneumonia, even in the neonatal age. three pre-described objectives. In the latter case, affected neonates may appear RESULTS septic and empyema or pneumothorax may 41% of the 117 pediatricians included in the occur. Differential diagnosis is with Congenital study knew about labia coalescence. The lowest Cystic Adenomatoid Malformation (CCAM), pul- rates of knowledge are reported in the South monary sequestration, and congenital pulmonary (6.7%) and Bekaa (13.3%) and Baalbek (0%). emphysema. Treatment is still controversial, and 80.3% of pediatricians routinely examine the no specific guidelines are presently available. female’s genitals. Male pediatricians who do Several strategies are adopted in different centers, not constitute 26% compared to 7.5% female including early surgery, selective bronchial pediatricians (p = 0.02). Regarding the incidence, ventilation or a conservative approach while the general average per year is 0.12%. 73% of waiting for spontaneous resolution. Early surgery pediatricians report that the diagnosis is made on is not always effective and may be associated with a routine, systematic physical examination. The postoperative complications and worse prognosis. coalescence of the labia minora is associated in However, surgery may be eventually necessary in 23% of the cases with a urinary infection and in prolonged unresolved cases. 16.65% with genitourinary symptoms. 10.4% of CASE REPORT pediatricians made the diagnosis following the An extremely preterm infant (GA = 26 weeks, BW discovery by the mother. 83.3% of the doctors = 670 g), was born by C-section for uncontrolled handled the case without pediatric gynecology maternal hypertension and altered cardiotocography. consult and then referred the patient to a pediatric Ante natal steroids were provided. At birth, the baby 2/66 Selected Abstracts of the 14th International Workshop on Neonatology • Cagliari (Italy) • October 24th-27th, 2018 Journal of Pediatric and Neonatal Individualized Medicine • vol. 7 • n. 2 • 2018 www.jpnim.com Open Access A. B. Figure 1 (ABS 2). Thorax X-ray of the case report. did need cardiopulmonary resuscitation, intubation, ipsilateral lung, we decided a conservative approach and 100% oxygen. Apgar score was 1, 3 and 5 at 1, 5 allowing a complete spontaneous resolution, at and 10 minutes, respectively. Exogenous surfactant the same time preserving parenchymal tissue and and prolonged mechanical ventilation were needed. avoiding invasive procedures. Further studies in At 2 weeks of life, a septic episode was treated with larger populations will have to confirm the benefit vancomycin and gentamicin. One week later, a of the wait-and-see attitude in these vulnerable chest X-ray (CXR) showed a large radiolucent area patients. within the right lung. Lung ultrasound (US) revealed REFERENCES a loculated area suggestive of a pseudocystic • Arora P, Kalra VK, Natarajan G. Pneumatoceles in infants in the neonatal lesion, compatible with a pneumatocele. Tracheal intensive care unit: clinical characteristics and outcomes. Am J Perinatol. aspirate yielded positive for S. aureus, blood 2013;30:689-94. culture for S. warneri. Rifampicin and cefotaxime • de Bie HM, van Toledo-Eppinga L, Verbeke JI, van Elburg RM. Neonatal were given for 3 weeks. A CT scan confirmed the pneumatocele as a complication of nasal continuous positive airway pressure. diagnosis of pneumatocele (large cystic loculated Arch Dis Fetal Neonatal Ed. 2002;86:F202-3. lesion, impronting the remaining parenchyma). • Hussain N, Noce T, Sharma P, Jagjivan, B, P. Hegde P, M. Pappagallo M, Progression was monitored by weekly US and CXR Bhandari A. Pneumatoceles in preterm infants: incidence and outcome in the (Fig. 1). We adopted a conservative approach based post-surfactant era. J Perinatology. 2010;30:330-6. on residual lung recruitment, righ-sided positioning, and appropriate analgesia. Moderate hypercapnia ABS 3 was tolerated with pH values > 7.22. To facilitate weaning from invasive ventilation, low dose METABOLOMICS IN NEWBORNS WITH INTRA- dexamethasone was also administered. Mechanical UTERINE GROWTH RESTRICTION: EFFECTS ventilation was discontinued after 7 weeks, OF MATERNAL SMOKING followed by noninvasive support and supplemental O2 for an additional 2 weeks. After 9 weeks since L. Corona, F. Cesare Marincola, S. Corbu, R. Pintus, the diagnosis, we observed a spontaneous, full V. Fanos, A. Dessì resolution of pneumatocele, with no obvious radiological signs of residual lung damage. Neonatal Intensive
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