Figure S6. Upstream regulatory regions of the LISP2 and MCAT genes and binding motifs of AP2-G2 on them Upstream 1.2 kb sequences of the LISP2 and MCAT genes were subjected to the promoter assay. The binding motifs of AP2-G2 on these regions and a single point mutation (Mut) added to the original motif sequences (WT) are shown. The position of the motif is indicated by the distance from the first methionine codon (ATG) of each gene. The images of AP2-G2 peaks created by Integrative Genomics Viewer are shown above the upstream sequences.

Table S1. Exflagellation rates and oocyst formation in AP2-G2(–) parasites genotype Exflagellationa number of oocystsb wild type 34.9 54.0±13.2 AP2-G(-)1 0 0 AP2-G(-)2 0 0 AP2-G2::GFP 28.1 61.8±28.1 aNumber of exflagellation per 105 erythrocytes bAverage of oocysts per mosquito calculated using 20 mosquitoes

Table S2. Summary of the phenotypes of the disruptants

Phenotypes in blood stages Proliferation in the circulation Normally proliferate in the circulation. Sexual commitment and differentiation Commit to sexual development and diverge from the asexual stage as wild types. Phenotypes in the gametocyte Cell volume Gametocytes remain small, not filling with the host erythrocyte. Sex-specific traits No sexual dimorphism is observed. Sex-specific gene expression Significantly decreased Gene expression at 19 hpi Expression of at least 354 genes decreases and expression of at least 164 genes increases. Phenotypes in mosquito stages Exflagellation Not detected Ookinetes Not produced Oocyst Not observed in the mosquito

Table S3. Genes whose expression decreased in AP2-G2(–) parasitesa .

IDb Functional annotationb

1 PBANKA_051500c 25 kDa ookinete surface antigen precursor (P25)

2 PBANKA_051490 28 kDa ookinete surface protein (P28)

3 PBANKA_011100 6-cysteine protein (P12)

4 PBANKA_030600 6-cysteine protein (P230p)

5 PBANKA_135970 6-cysteine protein (P47)

6 PBANKA_135960 6-cysteine protein (P48/45)

7 PBANKA_113750 actin-depolymerizing factor 2 (ADF2)

8 PBANKA_081180 actin-like protein, putative

9 PBANKA_082140 ADP-ribosylation factor-like protein

10 PBANKA_103240 alpha/beta hydrolase, putative

11 PBANKA_102030 ankyrin, putative

12 PBANKA_123260 apicortin, putative

13 PBANKA_091740 armadillo repeat protein PF16 (PF16)

14 PBANKA_052380 asparagine rich protein, putative

15 PBANKA_144900 aspartyl protease, putative

16 PBANKA_060620 blood stage antigen 41-3 precursor, putative

17 PBANKA_040820 calcium dependent protein kinase 3 (CDPK3)

18 PBANKA_130810 calmodulin-like protein

19 PBANKA_051910 CCAT-binding transcription factor-like protein, putative

20 PBANKA_041290 circumsporozoite- and TRAP-related protein (CTRP)

21 PBANKA_061700 conserved membrane protein, unknown function

22 PBANKA_010270 conserved Plasmodium protein, unknown function

23 PBANKA_010510 conserved Plasmodium protein, unknown function

24 PBANKA_010720 conserved Plasmodium protein, unknown function

25 PBANKA_010810 conserved Plasmodium protein, unknown function

26 PBANKA_010980 conserved Plasmodium protein, unknown function

27 PBANKA_011080 conserved Plasmodium protein, unknown function

28 PBANKA_020360 conserved Plasmodium protein, unknown function

29 PBANKA_020710 conserved Plasmodium protein, unknown function

30 PBANKA_021260 conserved Plasmodium protein, unknown function 31 PBANKA_030160 conserved Plasmodium protein, unknown function

32 PBANKA_030180 conserved Plasmodium protein, unknown function

33 PBANKA_030290 conserved Plasmodium protein, unknown function

34 PBANKA_031200 conserved Plasmodium protein, unknown function

35 PBANKA_031480 conserved Plasmodium protein, unknown function

36 PBANKA_040250 conserved Plasmodium protein, unknown function

37 PBANKA_040620 conserved Plasmodium protein, unknown function

38 PBANKA_040640 conserved Plasmodium protein, unknown function

39 PBANKA_040730 conserved Plasmodium protein, unknown function

40 PBANKA_041130 conserved Plasmodium protein, unknown function

41 PBANKA_041300 conserved Plasmodium protein, unknown function

42 PBANKA_041720 conserved Plasmodium protein, unknown function

43 PBANKA_050140 conserved Plasmodium protein, unknown function

44 PBANKA_050200 conserved Plasmodium protein, unknown function

45 PBANKA_050440 conserved Plasmodium protein, unknown function

46 PBANKA_051010 conserved Plasmodium protein, unknown function

47 PBANKA_051030 conserved Plasmodium protein, unknown function

48 PBANKA_052120 conserved Plasmodium protein, unknown function

49 PBANKA_052210 conserved Plasmodium protein, unknown function

50 PBANKA_052220 conserved Plasmodium protein, unknown function

51 PBANKA_052370 conserved Plasmodium protein, unknown function

52 PBANKA_060550 conserved Plasmodium protein, unknown function

53 PBANKA_060580 conserved Plasmodium protein, unknown function

54 PBANKA_061240 conserved Plasmodium protein, unknown function

55 PBANKA_062030 conserved Plasmodium protein, unknown function

56 PBANKA_062060 conserved Plasmodium protein, unknown function

57 PBANKA_062070 conserved Plasmodium protein, unknown function

58 PBANKA_062200 conserved Plasmodium protein, unknown function

59 PBANKA_070200 conserved Plasmodium protein, unknown function

60 PBANKA_070350 conserved Plasmodium protein, unknown function

61 PBANKA_070470 conserved Plasmodium protein, unknown function

62 PBANKA_070480 conserved Plasmodium protein, unknown function

63 PBANKA_070490 conserved Plasmodium protein, unknown function

64 PBANKA_070550 conserved Plasmodium protein, unknown function

65 PBANKA_070720 conserved Plasmodium protein, unknown function 66 PBANKA_071910 conserved Plasmodium protein, unknown function

67 PBANKA_071970 conserved Plasmodium protein, unknown function

68 PBANKA_072010 conserved Plasmodium protein, unknown function

69 PBANKA_072090 conserved Plasmodium protein, unknown function

70 PBANKA_080680 conserved Plasmodium protein, unknown function

71 PBANKA_080720 conserved Plasmodium protein, unknown function

72 PBANKA_081260 conserved Plasmodium protein, unknown function

73 PBANKA_081540 conserved Plasmodium protein, unknown function

74 PBANKA_082320 conserved Plasmodium protein, unknown function

75 PBANKA_082550 conserved Plasmodium protein, unknown function

76 PBANKA_082580 conserved Plasmodium protein, unknown function

77 PBANKA_082740 conserved Plasmodium protein, unknown function

78 PBANKA_082820 conserved Plasmodium protein, unknown function

79 PBANKA_082890 conserved Plasmodium protein, unknown function

80 PBANKA_083030 conserved Plasmodium protein, unknown function

81 PBANKA_083040 conserved Plasmodium protein, unknown function

82 PBANKA_083270 conserved Plasmodium protein, unknown function

83 PBANKA_090200 conserved Plasmodium protein, unknown function

84 PBANKA_090460 conserved Plasmodium protein, unknown function

85 PBANKA_090530 conserved Plasmodium protein, unknown function

86 PBANKA_090550 conserved Plasmodium protein, unknown function

87 PBANKA_090610 conserved Plasmodium protein, unknown function

88 PBANKA_090750 conserved Plasmodium protein, unknown function

89 PBANKA_090940 conserved Plasmodium protein, unknown function

90 PBANKA_091080 conserved Plasmodium protein, unknown function

91 PBANKA_091090 conserved Plasmodium protein, unknown function

92 PBANKA_091110 conserved Plasmodium protein, unknown function

93 PBANKA_091250 conserved Plasmodium protein, unknown function

94 PBANKA_091360 conserved Plasmodium protein, unknown function

95 PBANKA_091670 conserved Plasmodium protein, unknown function

96 PBANKA_092070 conserved Plasmodium protein, unknown function

97 PBANKA_092260 conserved Plasmodium protein, unknown function

98 PBANKA_092770 conserved Plasmodium protein, unknown function

99 PBANKA_093080 conserved Plasmodium protein, unknown function

100 PBANKA_093260 conserved Plasmodium protein, unknown function 101 PBANKA_093680 conserved Plasmodium protein, unknown function

102 PBANKA_093880 conserved Plasmodium protein, unknown function

103 PBANKA_094240 conserved Plasmodium protein, unknown function

104 PBANKA_094300 conserved Plasmodium protein, unknown function

105 PBANKA_094370 conserved Plasmodium protein, unknown function

106 PBANKA_100250 conserved Plasmodium protein, unknown function

107 PBANKA_100450 conserved Plasmodium protein, unknown function

108 PBANKA_100960 conserved Plasmodium protein, unknown function

109 PBANKA_100990 conserved Plasmodium protein, unknown function

110 PBANKA_101040 conserved Plasmodium protein, unknown function

111 PBANKA_101300 conserved Plasmodium protein, unknown function

112 PBANKA_101390 conserved Plasmodium protein, unknown function

113 PBANKA_101820 conserved Plasmodium protein, unknown function

114 PBANKA_101900 conserved Plasmodium protein, unknown function

115 PBANKA_102000 conserved Plasmodium protein, unknown function

116 PBANKA_102120 conserved Plasmodium protein, unknown function

117 PBANKA_102940 conserved Plasmodium protein, unknown function

118 PBANKA_102950 conserved Plasmodium protein, unknown function

119 PBANKA_103040 conserved Plasmodium protein, unknown function

120 PBANKA_103370 conserved Plasmodium protein, unknown function

121 PBANKA_103570 conserved Plasmodium protein, unknown function

122 PBANKA_103790 conserved Plasmodium protein, unknown function

123 PBANKA_103870 conserved Plasmodium protein, unknown function

124 PBANKA_103880 conserved Plasmodium protein, unknown function

125 PBANKA_110210 conserved Plasmodium protein, unknown function

126 PBANKA_110410 conserved Plasmodium protein, unknown function

127 PBANKA_110600 conserved Plasmodium protein, unknown function

128 PBANKA_110930 conserved Plasmodium protein, unknown function

129 PBANKA_110960 conserved Plasmodium protein, unknown function

130 PBANKA_110990 conserved Plasmodium protein, unknown function

131 PBANKA_111020 conserved Plasmodium protein, unknown function

132 PBANKA_111270 conserved Plasmodium protein, unknown function

133 PBANKA_111410 conserved Plasmodium protein, unknown function

134 PBANKA_111500 conserved Plasmodium protein, unknown function

135 PBANKA_111520 conserved Plasmodium protein, unknown function 136 PBANKA_111980 conserved Plasmodium protein, unknown function

137 PBANKA_112380 conserved Plasmodium protein, unknown function

138 PBANKA_112580 conserved Plasmodium protein, unknown function

139 PBANKA_112920 conserved Plasmodium protein, unknown function

140 PBANKA_113280 conserved Plasmodium protein, unknown function

141 PBANKA_113860 conserved Plasmodium protein, unknown function

142 PBANKA_113880 conserved Plasmodium protein, unknown function

143 PBANKA_113890 conserved Plasmodium protein, unknown function

144 PBANKA_113980 conserved Plasmodium protein, unknown function

145 PBANKA_114380 conserved Plasmodium protein, unknown function

146 PBANKA_114520 conserved Plasmodium protein, unknown function

147 PBANKA_120180 conserved Plasmodium protein, unknown function

148 PBANKA_120350 conserved Plasmodium protein, unknown function

149 PBANKA_120420 conserved Plasmodium protein, unknown function

150 PBANKA_120450 conserved Plasmodium protein, unknown function

151 PBANKA_120530 conserved Plasmodium protein, unknown function

152 PBANKA_120740 conserved Plasmodium protein, unknown function

153 PBANKA_120880 conserved Plasmodium protein, unknown function

154 PBANKA_120890 conserved Plasmodium protein, unknown function

155 PBANKA_120940 conserved Plasmodium protein, unknown function

156 PBANKA_120990 conserved Plasmodium protein, unknown function

157 PBANKA_121250 conserved Plasmodium protein, unknown function

158 PBANKA_121320 conserved Plasmodium protein, unknown function

159 PBANKA_121330 conserved Plasmodium protein, unknown function

160 PBANKA_121450 conserved Plasmodium protein, unknown function

161 PBANKA_122530 conserved Plasmodium protein, unknown function

162 PBANKA_122550 conserved Plasmodium protein, unknown function

163 PBANKA_122590 conserved Plasmodium protein, unknown function

164 PBANKA_122940 conserved Plasmodium protein, unknown function

165 PBANKA_123830 conserved Plasmodium protein, unknown function

166 PBANKA_123900 conserved Plasmodium protein, unknown function

167 PBANKA_130450 conserved Plasmodium protein, unknown function

168 PBANKA_131140 conserved Plasmodium protein, unknown function

169 PBANKA_131200 conserved Plasmodium protein, unknown function

170 PBANKA_131290 conserved Plasmodium protein, unknown function 171 PBANKA_131530 conserved Plasmodium protein, unknown function

172 PBANKA_131650 conserved Plasmodium protein, unknown function

173 PBANKA_131850 conserved Plasmodium protein, unknown function

174 PBANKA_131860 conserved Plasmodium protein, unknown function

175 PBANKA_132080 conserved Plasmodium protein, unknown function

176 PBANKA_132350 conserved Plasmodium protein, unknown function

177 PBANKA_132380 conserved Plasmodium protein, unknown function

178 PBANKA_132510 conserved Plasmodium protein, unknown function

179 PBANKA_132520 conserved Plasmodium protein, unknown function

180 PBANKA_132540 conserved Plasmodium protein, unknown function

181 PBANKA_132550 conserved Plasmodium protein, unknown function

182 PBANKA_132610 conserved Plasmodium protein, unknown function

183 PBANKA_132620 conserved Plasmodium protein, unknown function

184 PBANKA_132770 conserved Plasmodium protein, unknown function

185 PBANKA_132940 conserved Plasmodium protein, unknown function

186 PBANKA_132990 conserved Plasmodium protein, unknown function

187 PBANKA_133090 conserved Plasmodium protein, unknown function

188 PBANKA_133130 conserved Plasmodium protein, unknown function

189 PBANKA_133480 conserved Plasmodium protein, unknown function

190 PBANKA_133490 conserved Plasmodium protein, unknown function

191 PBANKA_133500 conserved Plasmodium protein, unknown function

192 PBANKA_133570 conserved Plasmodium protein, unknown function

193 PBANKA_133620 conserved Plasmodium protein, unknown function

194 PBANKA_133660 conserved Plasmodium protein, unknown function

195 PBANKA_133810 conserved Plasmodium protein, unknown function

196 PBANKA_134140 conserved Plasmodium protein, unknown function

197 PBANKA_134230 conserved Plasmodium protein, unknown function

198 PBANKA_134420 conserved Plasmodium protein, unknown function

199 PBANKA_134930 conserved Plasmodium protein, unknown function

200 PBANKA_134940 conserved Plasmodium protein, unknown function

201 PBANKA_135140 conserved Plasmodium protein, unknown function

202 PBANKA_135250 conserved Plasmodium protein, unknown function

203 PBANKA_135380 conserved Plasmodium protein, unknown function

204 PBANKA_135390 conserved Plasmodium protein, unknown function

205 PBANKA_135490 conserved Plasmodium protein, unknown function 206 PBANKA_136150 conserved Plasmodium protein, unknown function

207 PBANKA_136250 conserved Plasmodium protein, unknown function

208 PBANKA_136360 conserved Plasmodium protein, unknown function

209 PBANKA_140090 conserved Plasmodium protein, unknown function

210 PBANKA_140500 conserved Plasmodium protein, unknown function

211 PBANKA_140650 conserved Plasmodium protein, unknown function

212 PBANKA_140960 conserved Plasmodium protein, unknown function

213 PBANKA_141200 conserved Plasmodium protein, unknown function

214 PBANKA_141480 conserved Plasmodium protein, unknown function

215 PBANKA_141520 conserved Plasmodium protein, unknown function

216 PBANKA_141720 conserved Plasmodium protein, unknown function

217 PBANKA_141740 conserved Plasmodium protein, unknown function

218 PBANKA_141930 conserved Plasmodium protein, unknown function

219 PBANKA_142070 conserved Plasmodium protein, unknown function

220 PBANKA_142140 conserved Plasmodium protein, unknown function

221 PBANKA_142150 conserved Plasmodium protein, unknown function

222 PBANKA_142290 conserved Plasmodium protein, unknown function

223 PBANKA_142450 conserved Plasmodium protein, unknown function

224 PBANKA_142580 conserved Plasmodium protein, unknown function

225 PBANKA_142910 conserved Plasmodium protein, unknown function

226 PBANKA_142920 conserved Plasmodium protein, unknown function

227 PBANKA_143060 conserved Plasmodium protein, unknown function

228 PBANKA_143120 conserved Plasmodium protein, unknown function

229 PBANKA_143140 conserved Plasmodium protein, unknown function

230 PBANKA_143150 conserved Plasmodium protein, unknown function

231 PBANKA_143630 conserved Plasmodium protein, unknown function

232 PBANKA_143770 conserved Plasmodium protein, unknown function

233 PBANKA_144480 conserved Plasmodium protein, unknown function

234 PBANKA_144600 conserved Plasmodium protein, unknown function

235 PBANKA_145110 conserved Plasmodium protein, unknown function

236 PBANKA_145390 conserved Plasmodium protein, unknown function

237 PBANKA_145910 conserved Plasmodium protein, unknown function

238 PBANKA_146130 conserved Plasmodium protein, unknown function

239 PBANKA_146330 conserved Plasmodium protein, unknown function

240 PBANKA_146390 conserved Plasmodium protein, unknown function 241 PBANKA_132010 conserved Plasmodium protein, unknown function (UIS25)

242 PBANKA_123650 conserved Plasmodium protein, unknown function, fragment

243 PBANKA_123660 conserved Plasmodium protein, unknown function, fragment

244 PBANKA_071130 conserved protein, unknown function

245 PBANKA_050030 conserved rodent malaria protein, unknown function

246 PBANKA_090010 conserved rodent malaria protein, unknown function

247 PBANKA_094340 CPW-WPC family protein, putative

248 PBANKA_112880 CPW-WPC family protein, putative

249 PBANKA_121830 CPW-WPC family protein, putative

250 PBANKA_144930 CPW-WPC family protein, putative

251 PBANKA_123320 cyclin, putative

252 PBANKA_082440 cyclin-dependent kinase, putative

253 PBANKA_031270 DEAD/DEAH helicase, putative

254 PBANKA_051200 DHHC-type zinc finger protein, putative

255 PBANKA_041610 dynein heavy chain, putative

256 PBANKA_060120 dynein heavy chain, putative

257 PBANKA_070810 dynein light chain 1 (DLC1)

258 PBANKA_093360 dynein light chain 2, putative

259 PBANKA_082830 dynein light chain, putative

260 PBANKA_113360 dynein light chain, putative

261 PBANKA_101830 dynein-associated protein, putative

262 PBANKA_102240 dynein-associated protein, putative

263 PBANKA_136160 E1-E2 ATPase, putative

264 PBANKA_040560 EB1 homolog, putative

265 PBANKA_050430 flagellar outer arm dynein-associated protein, putative

266 PBANKA_070210 folate transporter 1, putative (FT1)

267 PBANKA_131270 gamete egress and sporozoite traversal protein (GEST)

268 PBANKA_142370 GDP-mannose 4,6-dehydratase, putative

269 PBANKA_111530 glideosome-associated protein 40, putative (GAP40)

270 PBANKA_143760 glideosome-associated protein 45, putative

271 PBANKA_121910 heat shock protein 90, putative

272 PBANKA_090710 inner membrane complex protein 1b (IMC1b)

273 PBANKA_143660 inner membrane complex protein 1h (IMC1h)

274 PBANKA_135850 inner membrane complex protein, putative

275 PBANKA_093900 ion channel protein, putative 276 PBANKA_145880 kinesin, putative

277 PBANKA_090250 kinesin-like protein, putative

278 PBANKA_060950 kinesin-related protein, putative

279 PBANKA_130070 LCCL domain-containing protein (CCp1)

280 PBANKA_131950 LCCL domain-containing protein (CCP2)

281 PBANKA_103520 LCCL domain-containing protein (CCp3)

282 PBANKA_041760 LCCL domain-containing protein (CCp4)

283 PBANKA_020450 LCCL domain-containing protein (CCp5)

284 PBANKA_133160 leucine-rich repeat protein (LRR14.1)

285 PBANKA_136060 leucine-rich repeat protein (LRR4.1)

286 PBANKA_083090 leucine-rich repeat protein (LRR8)

287 PBANKA_143220 male development gene 1 (MDV1)

288 PBANKA_121260 male gamete fusion factor HAP2 (HAP2)

289 PBANKA_071400 meiotic recombination protein DMC1-like protein, putative

290 PBANKA_040270 membrane skeletal protein, putative

291 PBANKA_070710 membrane skeletal protein, putative

292 PBANKA_111960 merozoite surface protein 10, putative (MSP10)

293 PBANKA_030390 metabolite/drug transporter, putative

294 PBANKA_123130 metabolite/drug transporter, putative

295 PBANKA_123350 mRNA-binding protein PUF1 (PUF1)

myosin light chain 1, putative,myosin A tail domain interacting protein MTIP, 296 PBANKA_145950 putative (MTIP)

297 PBANKA_124070 NIMA related kinase 2 (NEK2)

298 PBANKA_060060 NIMA related kinase 3, putative (NEK3)

299 PBANKA_103820 nuclear formin-like protein (MISFIT)

300 PBANKA_010440 nucleoside diphosphate kinase, putative

301 PBANKA_146300 osmiophilic body protein (G377)

302 PBANKA_134040 oxidoreductase, putative

303 PBANKA_143240 perforin like protein 2 (PPLP2)

304 PBANKA_082420 perforin like protein 3 (PPLP3)

305 PBANKA_092650 petidase, M16 family, putative

306 PBANKA_112040 Pfs77 homologue, putative

307 PBANKA_133370 phosphodiesterase delta (PDEdelta)

308 PBANKA_040970 plasmepsin VI

309 PBANKA_051760 plasmepsin VII, putative 310 PBANKA_132910 plasmepsin VIII, putative

311 PBANKA_020070 Plasmodium exported protein, unknown function

312 PBANKA_040030 Plasmodium exported protein, unknown function

313 PBANKA_110050 Plasmodium exported protein, unknown function

314 PBANKA_083710 Plasmodium exported protein, unknown function, fragment

315 PBANKA_040430 P-loop containing nucleoside triphospahte hydrolase, putative

316 PBANKA_100240 protease, putative

317 PBANKA_121710 protein kinase, putative

318 PBANKA_141450 protein kinase, putative

319 PBANKA_094230 radial spoke head protein, putative

320 PBANKA_080450 rhoptry associated membrane antigen, putative (RAMA)

321 PBANKA_131570 rhoptry neck protein 2 (RON2)

322 PBANKA_093200 rhoptry neck protein 4, putative (RON4)

323 PBANKA_061970 rhoptry-associated leucine zipper-like protein 1, putative (RALP1)

324 PBANKA_103210 rhoptry-associated protein 1, putative (RAP1)

325 PBANKA_110140 rhoptry-associated protein 2/3 (RAP2/3)

326 PBANKA_142770 RuvB DNA helicase, putative

327 PBANKA_103780 secreted ookinete adhesive protein (SOAP)

328 PBANKA_061920 secreted ookinete protein, putative (PSOP1)

329 PBANKA_111340 secreted ookinete protein, putative (PSOP12)

330 PBANKA_123360 secreted ookinete protein, putative (PSOP13)

331 PBANKA_142170 secreted ookinete protein, putative (PSOP20)

332 PBANKA_031140 serine/threonine protein kinase, putative

333 PBANKA_130520 serine/threonine protein kinase, putative

334 PBANKA_141360 serine/threonine protein kinase, putative

335 PBANKA_113310 serine/threonine protein kinase, putative (ARK3)

336 PBANKA_020580 serine/threonine protein kinase, putative (IK2)

337 PBANKA_101200 SF-assemblin, putative

338 PBANKA_010290 SPE2-interacting protein, putative (SIP2)

339 PBANKA_081070 subpellicular microtubule protein 1, putative (SPM1)

340 PBANKA_110710 subtilisin-like protease 1, putative (SUB1)

341 PBANKA_060510 Tat binding protein 1(TBP-1)-interacting protein, putative

342 PBANKA_082570 telomeric repeat binding factor 1, putative

343 PBANKA_132570 thioredoxin-like protein (TLP1)

344 PBANKA_051170 topoisomerase, putative 345 PBANKA_110800 transcription factor IIb, putative

346 PBANKA_103430 transcription factor with AP2 domain(s), putative

347 PBANKA_130050 tubulin, putative

348 PBANKA_111370 tubulin-tyrosine ligase, putative

349 PBANKA_120800 tubulin-tyrosine ligase, putative

350 PBANKA_123230 UTP--glucose-1-phosphate uridylyltransferase, putative

351 PBANKA_122890 von willebrand factor a-domain-related protein (WARP)

352 PBANKA_060860 zinc finger protein, putative

353 PBANKA_113490 zinc finger protein, putative

354 PBANKA_092730 zinc finger, DHHC-type, putative aDNA microarray analysis was performed between wild-type and AP2-G2(−) parasites using rats synchronously infected with P. berghei parasites. Infected blood was harvested 19 h after intravenous inoculation of cultured schizonts into rats. bGene ID and functional annotation were attributed to each gene according to those in PlasmoDB. Target genes were sorted in alphabetical order of attributed functional annotations. cGenes decreased over five-fold in AP2-G2(−) parasites are listed

Table S4. Sequences enriched around the summits of AP2-G2 peaks in the experiment 1a

six base sequence p-value motif 1 GTTGTAb 5.31E-137 GTTG(T/C) 2 TGTTGT 3.21E-106 GTTG(T/C) 3 TACAAC 1.85E-98 (A/G) CAAC 4 AGTTGT 4.61E-75 GTTG(T/C) 5 ACAACA 3.02E-73 (A/G) CAAC 6 ACAACT 1.99E-61 (A/G) CAAC 7 GTTGTT 4.34E-57 GTTG(T/C) 8 TGCAAC 1.99E-54 (A/G) CAAC 9 AACAAC 2.23E-42 (A/G) CAAC 10 GTTGCA 7.81E-42 GTTG(T/C) 11 GTGTTG 2.03E-39 GTTG(T/C) 12 ACAACC 2.06E-36 (A/G) CAAC 13 GCAACA 1.25E-33 (A/G) CAAC 14 CTGTTG 3.92E-32 (A/G) CAAC 15 TTGTTG 7.11E-31 GTTG(T/C) 16 GGTTGT 8.26E-30 GTTG(T/C) 17 ATGTTG 4.81E-29 GTTG(T/C) 18 CAACCA 5.10E-29 (A/G) CAAC 19 CAACAA 6.57E-29 (A/G) CAAC 20 TAGTTG 1.83E-28 GTTG(T/C) aFisher’s exact test was performed for all six base sequences between the 200-bp regions around the summits and other regions in P. berghei genome. bThe result is arranges from the sequence with the smallest p-value. Twenty sequences with the smallest p-values are shown

Table S5. Sequences enriched around the summits of AP2-G2 peaks in the experiment 2a

six base sequence p-value motif 1 GTTGTAb 3.25E-133 GTTG(T/C) 2 TACAAC 4.85E-120 (A/G) CAAC 3 TGTTGT 6.17E-105 GTTG(T/C) 4 ACAACA 3.55E-85 (A/G) CAAC 5 AGTTGT 7.25E-82 GTTG(T/C) 6 ACAACT 9.68E-80 (A/G) CAAC 7 GTTGTT 3.52E-68 GTTG(T/C) 8 AACAAC 5.23E-62 (A/G) CAAC 9 TGCAAC 6.01E-62 (A/G) CAAC 10 GTTGCA 1.24E-40 GTTG(T/C) 11 ACAACC 1.22E-38 (A/G) CAAC] 12 GTGTTG 1.22E-35 GTTG(T/C) 13 CAACCA 3.04E-35 (A/G) CAAC 14 GCAACT 3.85E-35 (A/G) CAAC 15 GGTTGT 1.41E-34 GTTG(T/C) 16 CTGTTG 1.16E-33 GTTG(T/C) 17 AGAACA 1.72E-32 - 18 TTGTTG 5.59E-31 GTTG(T/C) 19 CAACTG 1.62E-30 (A/G) CAAC 20 GCAACA 1.55E-29 (A/G) CAAC aFisher’s exact test was performed using the same procedures as those in experiment 1. bTwenty sequences with the smallest p-values are shown.

Table S6. Targets of AP2-G2a

Gene IDb Functional annotationb 1 PBANKA_113810 14-3-3 protein, putative 2 PBANKA_122800 1-cys peroxiredoxin, putative 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3 PBANKA_133060 putative 4 PBANKA_133410 20S proteasome beta 4 subunit, putative 5 PBANKA_051500 25 kDa ookinete surface antigen precursor (P25) 6 PBANKA_120660 26S proteasome regulatory subunit 4, putative 7 PBANKA_041030 26S proteasome regulatory subunit S14, putative 8 PBANKA_132970 26S proteasome subunit, putative 9 PBANKA_141980 3',5'-cyclic nucleotide phosphodiesterase, putative 10 PBANKA_061750 3'-5' exoribonuclease Csl4 homolog, putative 11 PBANKA_145440 3-hydroxyisobutyryl-coenzyme A hydrolase, putative 12 PBANKA_082380 3-oxoacyl-(acyl-carrier protein) reductase, putative 3-oxoacyl-acyl-carrier protein synthase, putative 13 PBANKA_112510 (FabB/FabF) 14 PBANKA_061720 40S ribosomal protein S10, putative 15 PBANKA_040540 40S ribosomal protein S12, putative 16 PBANKA_123100 40S ribosomal protein S14, putative 17 PBANKA_141630 40S ribosomal protein S15/S19, putative 18 PBANKA_041460 40S ribosomal protein S15A, putative 19 PBANKA_145610 40S ribosomal protein S17, putative 20 PBANKA_120190 40S ribosomal protein S20e, putative 21 PBANKA_090500 40S ribosomal protein S21e, putative 22 PBANKA_123420 40S ribosomal protein S24, putative 23 PBANKA_102200 40S ribosomal protein S25, putative 24 PBANKA_080340 40S ribosomal protein S29, putative 25 PBANKA_031560 40S ribosomal protein S30, putative 26 PBANKA_103940 40S ribosomal protein S31/UBI, putative 27 PBANKA_121560 40S ribosomal protein S3A, putative 28 PBANKA_061910 40S ribosomal protein S5, putative 29 PBANKA_135510 40S ribosomal protein S6, putative 30 PBANKA_140130 40S ribosomal protein S7, putative 31 PBANKA_030170 5'-3' exonuclease, putative 32 PBANKA_124230 58 kDa phosphoprotein,heat shock-related protein (HRP) 33 PBANKA_144680 60 kDa chaperonin, putative (CPN60) 34 PBANKA_040770 60S acidic ribosomal protein P2, putative 35 PBANKA_094360 60S acidic ribosomal protein, putative 36 PBANKA_102840 60S ribosomal protein L10, putative 37 PBANKA_061710 60S ribosomal protein L11a, putative 38 PBANKA_123180 60S ribosomal protein L12, putative 39 PBANKA_101310 60S ribosomal protein L14, putative 40 PBANKA_136420 60S ribosomal protein L17, putative 41 PBANKA_122920 60S ribosomal protein L19, putative 42 PBANKA_070910 60S ribosomal protein L22, putative 43 PBANKA_134670 60S ribosomal protein L23, putative 44 PBANKA_133860 60S ribosomal protein L23a, putative 45 PBANKA_041060 60S ribosomal protein L26, putative 46 PBANKA_090650 60S ribosomal protein L28, putative 47 PBANKA_051190 60S ribosomal protein L3, putative 48 PBANKA_050360 60S ribosomal protein L30e, putative 49 PBANKA_122120 60S ribosomal protein L34a, putative 50 PBANKA_092340 60S ribosomal protein L35, putative 51 PBANKA_090640 60S ribosomal protein L35ae, putative 52 PBANKA_030700 60S ribosomal protein L37ae, putative 53 PBANKA_091810 60S ribosomal protein L38e, putative 54 PBANKA_114170 60S ribosomal protein L40/UBI, putative 55 PBANKA_090470 60S ribosomal protein L41, putative 56 PBANKA_133830 60S ribosomal protein L6, putative 57 PBANKA_135190 60S ribosomal protein L6-2, putative 58 PBANKA_040550 60S ribosomal protein L7, putative 59 PBANKA_113120 60S ribosomal protein L7-2, putative 60 PBANKA_123170 60S ribosomal protein L8, putative 61 PBANKA_091800 60S ribosomal protein, putative 62 PBANKA_021340 60S ribosomal subunit export protein, putative 63 PBANKA_110570 60S ribosomal subunit protein L24, putative 64 PBANKA_100210 6-cysteine protein (P36) 65 PBANKA_091870 A/G-specific adenine glycosylase, putative 66 PBANKA_080460 AAA family ATPase, putative 67 PBANKA_102990 AAA family ATPase, putative 68 PBANKA_122670 AAA family ATPase, putative 69 PBANKA_135330 ABC transporter, putative 70 PBANKA_136480 ABC transporter, putative 71 PBANKA_142730 ABC1 family, putative 72 PBANKA_131460 acetyl-CoA acetyltransferase, putative 73 PBANKA_135520 aconitase, putative 74 PBANKA_145930 actin I 75 PBANKA_110310 actin-depolymerizing factor 1 (ADF1) 76 PBANKA_061680 actin-related protein 77 PBANKA_102060 actin-related protein homolog, putative 78 PBANKA_110480 actin-related protein, putative 79 PBANKA_040460 activator of Hsp90 ATPase, putative (AHA1) 80 PBANKA_030560 acyl carrier protein, putative (ACP) 81 PBANKA_121620 acyl CoA:diacylglycerol acyltransferase, putative 82 PBANKA_145330 acyl-CoA synthetase, putative 83 PBANKA_021430 adapter-related protein, putative 84 PBANKA_130460 adaptor complexes medium subunit family adaptor-related protein complex 3, sigma 2 subunit, 85 PBANKA_146340 putative 86 PBANKA_051360 adenosine deaminase, putative 87 PBANKA_133740 adenosine-diphosphatase, putative 88 PBANKA_123560 adenosylhomocysteinase, putative (SAHH) 89 PBANKA_071760 adenylate kinase 1, putative 90 PBANKA_120720 adenylate kinase, putative (AK1) 91 PBANKA_122760 adenylyl cyclase beta, putative (ACbeta) 92 PBANKA_100290 ag-1 blood stage membrane protein homologue alanine--tRNA ligase, putative,alanyl-tRNA synthetase, 93 PBANKA_114360 putative (AlaRS) 94 PBANKA_114050 aldo-keto reductase, putative 95 PBANKA_130440 allantoicase, putative 96 PBANKA_091590 amino acid transporter, putative 97 PBANKA_134440 AMP deaminase, putative 98 PBANKA_143320 anaphase promoting complex subunit 10, putative 99 PBANKA_102030 ankyrin, putative 100 PBANKA_091500 apical membrane antigen 1 (AMA1) 101 PBANKA_072180 apical merozoite protein, putative 102 PBANKA_141670 apicoplast glycerol-3-phosphate acyltransferase, putative 103 PBANKA_090430 apicoplast import protein Tic20, putative (TIC20) 104 PBANKA_011170 apicoplast ribosomal protein L18 precursor, putative 105 PBANKA_142740 apicoplast ribosomal protein L33 precursor, putative 106 PBANKA_093770 apicoplast ribosomal protein L36e precursor, putative 107 PBANKA_094080 apicoplast ribosomal protein S15 precursor, putative 108 PBANKA_131250 Appr-1-p processing domain protein 109 PBANKA_134740 apurinic/apyrimidinic endonuclease, putative 110 PBANKA_091560 aquaglyceroporin (AQP) 111 PBANKA_041480 arginase 112 PBANKA_101840 arginine methyltransferase 1, putative (PRMT1) 113 PBANKA_040760 asparagine synthetase, putative 114 PBANKA_020760 asparagine-rich antigen, putative 115 PBANKA_142810 asparagine-rich antigen, putative 116 PBANKA_030230 aspartate aminotransferase, putative 117 PBANKA_135770 aspartate carbamoyltransferase, putative 118 PBANKA_083310 aspartyl aminopeptidase, putative 119 PBANKA_021020 aspartyl-tRNA synthetase, putative 120 PBANKA_041650 ATPase, putative 121 PBANKA_143740 ATP-binding protein, putative 122 PBANKA_061200 ATP-dependent Clp protease proteolytic subunit, putative 123 PBANKA_103560 ATP-dependent Clp protease, putative 124 PBANKA_140120 ATP-dependent DEAD box helicase, putative 125 PBANKA_132830 ATP-dependent protease la, putative 126 PBANKA_132270 ATP-dependent RNA helicase DBP5, putative 127 PBANKA_070950 ATP-dependent RNA helicase prh1, putative 128 PBANKA_100270 ATP-dependent RNA helicase, putative 129 PBANKA_102410 ATP-dependent RNA helicase, putative 130 PBANKA_041570 autophagy-related protein 3, putative (ATG3) 131 PBANKA_050410 autophagy-related protein 8, putative (ATG8) 132 PBANKA_010200 bcs1-like protein, putative 133 PBANKA_093240 berghepain-2 (BP2) 134 PBANKA_072060 Bet3 transport protein, putative 135 PBANKA_133820 beta-hydroxyacyl-ACP dehydratase, putative (FabZ) 136 PBANKA_142960 bi-functional aminoacyl-tRNA synthetase, putative 137 PBANKA_051100 biotin--acetyl-CoA-carboxylase, putative 138 PBANKA_010050 BIR protein 139 PBANKA_020125 BIR protein, pseudogene 140 PBANKA_083655 BIR protein, pseudogene 141 PBANKA_020145 BIR protein, pseudogene, fragment 142 PBANKA_103640 BOP1-like protein, putative 143 PBANKA_071170 BRIX domain, putative 144 PBANKA_021350 BRIX protein, putative 145 PBANKA_122640 cactin homolog, putative 146 PBANKA_031420 calcium dependent protein kinase 1 (CDPK1) 147 PBANKA_135150 calcium dependent protein kinase 5 (CDPK5) 148 PBANKA_142160 calcium/calmodulin-dependent protein kinase, putative 149 PBANKA_101060 calmodulin, putative 150 PBANKA_071620 calmodulin-like protein, putative 151 PBANKA_094140 caltractin (centrin), putative (CEN4) CAMP-dependent protein kinase regulatory subunit, 152 PBANKA_143800 putative (PKAr) 153 PBANKA_090510 carbohydrate kinase, putative 154 PBANKA_093860 casein kinase 2, alpha subunit (CK2alpha) 155 PBANKA_021190 cation transporting ATPase, putative 156 PBANKA_010230 cation/H antiporter, putative (CHA) 157 PBANKA_090260 CCAAT-box DNA binding protein subunit B, putative 158 PBANKA_051910 CCAT-binding transcription factor-like protein, putative 159 PBANKA_051920 CCAT-binding transcription factor-like protein, putative CCR4-NOT transcription complex subunit 1, putative 160 PBANKA_094310 (NOT1) CCR4-NOT transcription complex subunit 4, putative 161 PBANKA_144990 (NOT4) 162 PBANKA_071990 cdc2-related protein kinase 1 (CRK1) 163 PBANKA_040130 CDGSH iron-sulfur domain-containing protein, putative 164 PBANKA_145280 cell cycle control protein, putative 165 PBANKA_124400 cell cycle regulator protein, putative 166 PBANKA_110720 cell differentiation protein, putative (CAF40) cell traversal protein for ookinetes and sporozoites 167 PBANKA_143230 (CelTOS) 168 PBANKA_051180 centrin-3, putative 169 PBANKA_121960 cg1 protein, putative 170 PBANKA_121940 Cg3 protein, putative 171 PBANKA_080050 chitinase (CHT1) 172 PBANKA_121950 chloroquine resistance transporter, putative (CRT) 173 PBANKA_104010 choline kinase (CK) 174 PBANKA_112700 choline/ethanolaminephosphotransferase (CEPT) 175 PBANKA_112190 chorismate synthase, putative (CS) 176 PBANKA_092670 circumsporozoite-related antigen 177 PBANKA_050670 citrate synthase, mitochondrial precursor, putative 178 PBANKA_145890 clathrin coat assembly protein AP180, putative 179 PBANKA_031400 clathrin coat assembly protein, putative 180 PBANKA_140990 clathrin-adaptor medium chain, putative 181 PBANKA_070920 clp1-related protein, putative 182 PBANKA_071420 ClpB protein, putative 183 PBANKA_010540 coatomer alpha subunit, putative 184 PBANKA_131740 co-chaperone p23, putative 185 PBANKA_061700 conserved membrane protein, unknown function conserved Plasmodium membrane protein, unknown 186 PBANKA_100330 function 187 PBANKA_010260 conserved Plasmodium protein, unknown function 188 PBANKA_010280 conserved Plasmodium protein, unknown function 189 PBANKA_010530 conserved Plasmodium protein, unknown function 190 PBANKA_010580 conserved Plasmodium protein, unknown function 191 PBANKA_010695 conserved Plasmodium protein, unknown function 192 PBANKA_010890 conserved Plasmodium protein, unknown function 193 PBANKA_010900 conserved Plasmodium protein, unknown function 194 PBANKA_010930 conserved Plasmodium protein, unknown function 195 PBANKA_010990 conserved Plasmodium protein, unknown function 196 PBANKA_011010 conserved Plasmodium protein, unknown function 197 PBANKA_011060 conserved Plasmodium protein, unknown function 198 PBANKA_011130 conserved Plasmodium protein, unknown function 199 PBANKA_011140 conserved Plasmodium protein, unknown function 200 PBANKA_011240 conserved Plasmodium protein, unknown function 201 PBANKA_020500 conserved Plasmodium protein, unknown function 202 PBANKA_020550 conserved Plasmodium protein, unknown function 203 PBANKA_020600 conserved Plasmodium protein, unknown function 204 PBANKA_020690 conserved Plasmodium protein, unknown function 205 PBANKA_020750 conserved Plasmodium protein, unknown function 206 PBANKA_020890 conserved Plasmodium protein, unknown function 207 PBANKA_020900 conserved Plasmodium protein, unknown function 208 PBANKA_021070 conserved Plasmodium protein, unknown function 209 PBANKA_021180 conserved Plasmodium protein, unknown function 210 PBANKA_021200 conserved Plasmodium protein, unknown function 211 PBANKA_021280 conserved Plasmodium protein, unknown function 212 PBANKA_021370 conserved Plasmodium protein, unknown function 213 PBANKA_021450 conserved Plasmodium protein, unknown function 214 PBANKA_030160 conserved Plasmodium protein, unknown function 215 PBANKA_030200 conserved Plasmodium protein, unknown function 216 PBANKA_030350 conserved Plasmodium protein, unknown function 217 PBANKA_030410 conserved Plasmodium protein, unknown function 218 PBANKA_030580 conserved Plasmodium protein, unknown function 219 PBANKA_030590 conserved Plasmodium protein, unknown function 220 PBANKA_030660 conserved Plasmodium protein, unknown function 221 PBANKA_030770 conserved Plasmodium protein, unknown function 222 PBANKA_030780 conserved Plasmodium protein, unknown function 223 PBANKA_030790 conserved Plasmodium protein, unknown function 224 PBANKA_031120 conserved Plasmodium protein, unknown function 225 PBANKA_031130 conserved Plasmodium protein, unknown function 226 PBANKA_031210 conserved Plasmodium protein, unknown function 227 PBANKA_031290 conserved Plasmodium protein, unknown function 228 PBANKA_031300 conserved Plasmodium protein, unknown function 229 PBANKA_031370 conserved Plasmodium protein, unknown function 230 PBANKA_031390 conserved Plasmodium protein, unknown function 231 PBANKA_031410 conserved Plasmodium protein, unknown function 232 PBANKA_031430 conserved Plasmodium protein, unknown function 233 PBANKA_031440 conserved Plasmodium protein, unknown function 234 PBANKA_031460 conserved Plasmodium protein, unknown function 235 PBANKA_031490 conserved Plasmodium protein, unknown function 236 PBANKA_031570 conserved Plasmodium protein, unknown function 237 PBANKA_040170 conserved Plasmodium protein, unknown function 238 PBANKA_040330 conserved Plasmodium protein, unknown function 239 PBANKA_040380 conserved Plasmodium protein, unknown function 240 PBANKA_040390 conserved Plasmodium protein, unknown function 241 PBANKA_040490 conserved Plasmodium protein, unknown function 242 PBANKA_040500 conserved Plasmodium protein, unknown function 243 PBANKA_040510 conserved Plasmodium protein, unknown function 244 PBANKA_040660 conserved Plasmodium protein, unknown function 245 PBANKA_040690 conserved Plasmodium protein, unknown function 246 PBANKA_040950 conserved Plasmodium protein, unknown function 247 PBANKA_040960 conserved Plasmodium protein, unknown function 248 PBANKA_040990 conserved Plasmodium protein, unknown function 249 PBANKA_041000 conserved Plasmodium protein, unknown function 250 PBANKA_041020 conserved Plasmodium protein, unknown function 251 PBANKA_041070 conserved Plasmodium protein, unknown function 252 PBANKA_041140 conserved Plasmodium protein, unknown function 253 PBANKA_041150 conserved Plasmodium protein, unknown function 254 PBANKA_041320 conserved Plasmodium protein, unknown function 255 PBANKA_041370 conserved Plasmodium protein, unknown function 256 PBANKA_041380 conserved Plasmodium protein, unknown function 257 PBANKA_041420 conserved Plasmodium protein, unknown function 258 PBANKA_041430 conserved Plasmodium protein, unknown function 259 PBANKA_041840 conserved Plasmodium protein, unknown function 260 PBANKA_050140 conserved Plasmodium protein, unknown function 261 PBANKA_050150 conserved Plasmodium protein, unknown function 262 PBANKA_050180 conserved Plasmodium protein, unknown function 263 PBANKA_050260 conserved Plasmodium protein, unknown function 264 PBANKA_050265 conserved Plasmodium protein, unknown function 265 PBANKA_050280 conserved Plasmodium protein, unknown function 266 PBANKA_050440 conserved Plasmodium protein, unknown function 267 PBANKA_050490 conserved Plasmodium protein, unknown function 268 PBANKA_050530 conserved Plasmodium protein, unknown function 269 PBANKA_050600 conserved Plasmodium protein, unknown function 270 PBANKA_050680 conserved Plasmodium protein, unknown function 271 PBANKA_050690 conserved Plasmodium protein, unknown function 272 PBANKA_050800 conserved Plasmodium protein, unknown function 273 PBANKA_050820 conserved Plasmodium protein, unknown function 274 PBANKA_050860 conserved Plasmodium protein, unknown function 275 PBANKA_050870 conserved Plasmodium protein, unknown function 276 PBANKA_050940 conserved Plasmodium protein, unknown function 277 PBANKA_050950 conserved Plasmodium protein, unknown function 278 PBANKA_051000 conserved Plasmodium protein, unknown function 279 PBANKA_051010 conserved Plasmodium protein, unknown function 280 PBANKA_051070 conserved Plasmodium protein, unknown function 281 PBANKA_051080 conserved Plasmodium protein, unknown function 282 PBANKA_051110 conserved Plasmodium protein, unknown function 283 PBANKA_051270 conserved Plasmodium protein, unknown function 284 PBANKA_051290 conserved Plasmodium protein, unknown function 285 PBANKA_051310 conserved Plasmodium protein, unknown function 286 PBANKA_051350 conserved Plasmodium protein, unknown function 287 PBANKA_051370 conserved Plasmodium protein, unknown function 288 PBANKA_051440 conserved Plasmodium protein, unknown function 289 PBANKA_051510 conserved Plasmodium protein, unknown function 290 PBANKA_051640 conserved Plasmodium protein, unknown function 291 PBANKA_051810 conserved Plasmodium protein, unknown function 292 PBANKA_051930 conserved Plasmodium protein, unknown function 293 PBANKA_051940 conserved Plasmodium protein, unknown function 294 PBANKA_051950 conserved Plasmodium protein, unknown function 295 PBANKA_052010 conserved Plasmodium protein, unknown function 296 PBANKA_052330 conserved Plasmodium protein, unknown function 297 PBANKA_052370 conserved Plasmodium protein, unknown function 298 PBANKA_052440 conserved Plasmodium protein, unknown function 299 PBANKA_060170 conserved Plasmodium protein, unknown function 300 PBANKA_060250 conserved Plasmodium protein, unknown function 301 PBANKA_060330 conserved Plasmodium protein, unknown function 302 PBANKA_060340 conserved Plasmodium protein, unknown function 303 PBANKA_060350 conserved Plasmodium protein, unknown function 304 PBANKA_060370 conserved Plasmodium protein, unknown function 305 PBANKA_060390 conserved Plasmodium protein, unknown function 306 PBANKA_060430 conserved Plasmodium protein, unknown function 307 PBANKA_060450 conserved Plasmodium protein, unknown function 308 PBANKA_060490 conserved Plasmodium protein, unknown function 309 PBANKA_060540 conserved Plasmodium protein, unknown function 310 PBANKA_060600 conserved Plasmodium protein, unknown function 311 PBANKA_060910 conserved Plasmodium protein, unknown function 312 PBANKA_060920 conserved Plasmodium protein, unknown function 313 PBANKA_061230 conserved Plasmodium protein, unknown function 314 PBANKA_061330 conserved Plasmodium protein, unknown function 315 PBANKA_061390 conserved Plasmodium protein, unknown function 316 PBANKA_061400 conserved Plasmodium protein, unknown function 317 PBANKA_061470 conserved Plasmodium protein, unknown function 318 PBANKA_061490 conserved Plasmodium protein, unknown function 319 PBANKA_061640 conserved Plasmodium protein, unknown function 320 PBANKA_061650 conserved Plasmodium protein, unknown function 321 PBANKA_061660 conserved Plasmodium protein, unknown function 322 PBANKA_061780 conserved Plasmodium protein, unknown function 323 PBANKA_061870 conserved Plasmodium protein, unknown function 324 PBANKA_062060 conserved Plasmodium protein, unknown function 325 PBANKA_062070 conserved Plasmodium protein, unknown function 326 PBANKA_062100 conserved Plasmodium protein, unknown function 327 PBANKA_062110 conserved Plasmodium protein, unknown function 328 PBANKA_062230 conserved Plasmodium protein, unknown function 329 PBANKA_062260 conserved Plasmodium protein, unknown function 330 PBANKA_062280 conserved Plasmodium protein, unknown function 331 PBANKA_070120 conserved Plasmodium protein, unknown function 332 PBANKA_070180 conserved Plasmodium protein, unknown function 333 PBANKA_070240 conserved Plasmodium protein, unknown function 334 PBANKA_070480 conserved Plasmodium protein, unknown function 335 PBANKA_070490 conserved Plasmodium protein, unknown function 336 PBANKA_070520 conserved Plasmodium protein, unknown function 337 PBANKA_070530 conserved Plasmodium protein, unknown function 338 PBANKA_070570 conserved Plasmodium protein, unknown function 339 PBANKA_070770 conserved Plasmodium protein, unknown function 340 PBANKA_070780 conserved Plasmodium protein, unknown function 341 PBANKA_070960 conserved Plasmodium protein, unknown function 342 PBANKA_070990 conserved Plasmodium protein, unknown function 343 PBANKA_071000 conserved Plasmodium protein, unknown function 344 PBANKA_071030 conserved Plasmodium protein, unknown function 345 PBANKA_071180 conserved Plasmodium protein, unknown function 346 PBANKA_071220 conserved Plasmodium protein, unknown function 347 PBANKA_071300 conserved Plasmodium protein, unknown function 348 PBANKA_071320 conserved Plasmodium protein, unknown function 349 PBANKA_071340 conserved Plasmodium protein, unknown function 350 PBANKA_071410 conserved Plasmodium protein, unknown function 351 PBANKA_071440 conserved Plasmodium protein, unknown function 352 PBANKA_071450 conserved Plasmodium protein, unknown function 353 PBANKA_071530 conserved Plasmodium protein, unknown function 354 PBANKA_071540 conserved Plasmodium protein, unknown function 355 PBANKA_071630 conserved Plasmodium protein, unknown function 356 PBANKA_071640 conserved Plasmodium protein, unknown function 357 PBANKA_071690 conserved Plasmodium protein, unknown function 358 PBANKA_072000 conserved Plasmodium protein, unknown function 359 PBANKA_072050 conserved Plasmodium protein, unknown function 360 PBANKA_072090 conserved Plasmodium protein, unknown function 361 PBANKA_072160 conserved Plasmodium protein, unknown function 362 PBANKA_080030 conserved Plasmodium protein, unknown function 363 PBANKA_080090 conserved Plasmodium protein, unknown function 364 PBANKA_080100 conserved Plasmodium protein, unknown function 365 PBANKA_080110 conserved Plasmodium protein, unknown function 366 PBANKA_080140 conserved Plasmodium protein, unknown function 367 PBANKA_080180 conserved Plasmodium protein, unknown function 368 PBANKA_080200 conserved Plasmodium protein, unknown function 369 PBANKA_080240 conserved Plasmodium protein, unknown function 370 PBANKA_080270 conserved Plasmodium protein, unknown function 371 PBANKA_080280 conserved Plasmodium protein, unknown function 372 PBANKA_080390 conserved Plasmodium protein, unknown function 373 PBANKA_080420 conserved Plasmodium protein, unknown function 374 PBANKA_080440 conserved Plasmodium protein, unknown function 375 PBANKA_080480 conserved Plasmodium protein, unknown function 376 PBANKA_080640 conserved Plasmodium protein, unknown function 377 PBANKA_080810 conserved Plasmodium protein, unknown function 378 PBANKA_080850 conserved Plasmodium protein, unknown function 379 PBANKA_080950 conserved Plasmodium protein, unknown function 380 PBANKA_080960 conserved Plasmodium protein, unknown function 381 PBANKA_081010 conserved Plasmodium protein, unknown function 382 PBANKA_081080 conserved Plasmodium protein, unknown function 383 PBANKA_081150 conserved Plasmodium protein, unknown function 384 PBANKA_081220 conserved Plasmodium protein, unknown function 385 PBANKA_081250 conserved Plasmodium protein, unknown function 386 PBANKA_081260 conserved Plasmodium protein, unknown function 387 PBANKA_081330 conserved Plasmodium protein, unknown function 388 PBANKA_081370 conserved Plasmodium protein, unknown function 389 PBANKA_081380 conserved Plasmodium protein, unknown function 390 PBANKA_081410 conserved Plasmodium protein, unknown function 391 PBANKA_081480 conserved Plasmodium protein, unknown function 392 PBANKA_081510 conserved Plasmodium protein, unknown function 393 PBANKA_081690 conserved Plasmodium protein, unknown function 394 PBANKA_081740 conserved Plasmodium protein, unknown function 395 PBANKA_081760 conserved Plasmodium protein, unknown function 396 PBANKA_081780 conserved Plasmodium protein, unknown function 397 PBANKA_081790 conserved Plasmodium protein, unknown function 398 PBANKA_081940 conserved Plasmodium protein, unknown function 399 PBANKA_081960 conserved Plasmodium protein, unknown function 400 PBANKA_082270 conserved Plasmodium protein, unknown function 401 PBANKA_082280 conserved Plasmodium protein, unknown function 402 PBANKA_082320 conserved Plasmodium protein, unknown function 403 PBANKA_082370 conserved Plasmodium protein, unknown function 404 PBANKA_082530 conserved Plasmodium protein, unknown function 405 PBANKA_082540 conserved Plasmodium protein, unknown function 406 PBANKA_082550 conserved Plasmodium protein, unknown function 407 PBANKA_082590 conserved Plasmodium protein, unknown function 408 PBANKA_082740 conserved Plasmodium protein, unknown function 409 PBANKA_082840 conserved Plasmodium protein, unknown function 410 PBANKA_082920 conserved Plasmodium protein, unknown function 411 PBANKA_083040 conserved Plasmodium protein, unknown function 412 PBANKA_083045 conserved Plasmodium protein, unknown function 413 PBANKA_083110 conserved Plasmodium protein, unknown function 414 PBANKA_083210 conserved Plasmodium protein, unknown function 415 PBANKA_083220 conserved Plasmodium protein, unknown function 416 PBANKA_083290 conserved Plasmodium protein, unknown function 417 PBANKA_083370 conserved Plasmodium protein, unknown function 418 PBANKA_083500 conserved Plasmodium protein, unknown function 419 PBANKA_083510 conserved Plasmodium protein, unknown function 420 PBANKA_083540 conserved Plasmodium protein, unknown function 421 PBANKA_083550 conserved Plasmodium protein, unknown function 422 PBANKA_083590 conserved Plasmodium protein, unknown function 423 PBANKA_083620 conserved Plasmodium protein, unknown function 424 PBANKA_090180 conserved Plasmodium protein, unknown function 425 PBANKA_090280 conserved Plasmodium protein, unknown function 426 PBANKA_090290 conserved Plasmodium protein, unknown function 427 PBANKA_090315 conserved Plasmodium protein, unknown function 428 PBANKA_090320 conserved Plasmodium protein, unknown function 429 PBANKA_090330 conserved Plasmodium protein, unknown function 430 PBANKA_090340 conserved Plasmodium protein, unknown function 431 PBANKA_090420 conserved Plasmodium protein, unknown function 432 PBANKA_090460 conserved Plasmodium protein, unknown function 433 PBANKA_090520 conserved Plasmodium protein, unknown function 434 PBANKA_090610 conserved Plasmodium protein, unknown function 435 PBANKA_090620 conserved Plasmodium protein, unknown function 436 PBANKA_090630 conserved Plasmodium protein, unknown function 437 PBANKA_090670 conserved Plasmodium protein, unknown function 438 PBANKA_090680 conserved Plasmodium protein, unknown function 439 PBANKA_090880 conserved Plasmodium protein, unknown function 440 PBANKA_090910 conserved Plasmodium protein, unknown function 441 PBANKA_090920 conserved Plasmodium protein, unknown function 442 PBANKA_091090 conserved Plasmodium protein, unknown function 443 PBANKA_091190 conserved Plasmodium protein, unknown function 444 PBANKA_091200 conserved Plasmodium protein, unknown function 445 PBANKA_091220 conserved Plasmodium protein, unknown function 446 PBANKA_091240 conserved Plasmodium protein, unknown function 447 PBANKA_091390 conserved Plasmodium protein, unknown function 448 PBANKA_091400 conserved Plasmodium protein, unknown function 449 PBANKA_091490 conserved Plasmodium protein, unknown function 450 PBANKA_091510 conserved Plasmodium protein, unknown function 451 PBANKA_091520 conserved Plasmodium protein, unknown function 452 PBANKA_091530 conserved Plasmodium protein, unknown function 453 PBANKA_091630 conserved Plasmodium protein, unknown function 454 PBANKA_091650 conserved Plasmodium protein, unknown function 455 PBANKA_091670 conserved Plasmodium protein, unknown function 456 PBANKA_091680 conserved Plasmodium protein, unknown function 457 PBANKA_091770 conserved Plasmodium protein, unknown function 458 PBANKA_091840 conserved Plasmodium protein, unknown function 459 PBANKA_091850 conserved Plasmodium protein, unknown function 460 PBANKA_091970 conserved Plasmodium protein, unknown function 461 PBANKA_092060 conserved Plasmodium protein, unknown function 462 PBANKA_092090 conserved Plasmodium protein, unknown function 463 PBANKA_092100 conserved Plasmodium protein, unknown function 464 PBANKA_092120 conserved Plasmodium protein, unknown function 465 PBANKA_092140 conserved Plasmodium protein, unknown function 466 PBANKA_092170 conserved Plasmodium protein, unknown function 467 PBANKA_092240 conserved Plasmodium protein, unknown function 468 PBANKA_092250 conserved Plasmodium protein, unknown function 469 PBANKA_092260 conserved Plasmodium protein, unknown function 470 PBANKA_092410 conserved Plasmodium protein, unknown function 471 PBANKA_092720 conserved Plasmodium protein, unknown function 472 PBANKA_092840 conserved Plasmodium protein, unknown function 473 PBANKA_093100 conserved Plasmodium protein, unknown function 474 PBANKA_093110 conserved Plasmodium protein, unknown function 475 PBANKA_093260 conserved Plasmodium protein, unknown function 476 PBANKA_093280 conserved Plasmodium protein, unknown function 477 PBANKA_093510 conserved Plasmodium protein, unknown function 478 PBANKA_093660 conserved Plasmodium protein, unknown function 479 PBANKA_093670 conserved Plasmodium protein, unknown function 480 PBANKA_093730 conserved Plasmodium protein, unknown function 481 PBANKA_093750 conserved Plasmodium protein, unknown function 482 PBANKA_093880 conserved Plasmodium protein, unknown function 483 PBANKA_094070 conserved Plasmodium protein, unknown function 484 PBANKA_094210 conserved Plasmodium protein, unknown function 485 PBANKA_100170 conserved Plasmodium protein, unknown function 486 PBANKA_100250 conserved Plasmodium protein, unknown function 487 PBANKA_100320 conserved Plasmodium protein, unknown function 488 PBANKA_100350 conserved Plasmodium protein, unknown function 489 PBANKA_100370 conserved Plasmodium protein, unknown function 490 PBANKA_100410 conserved Plasmodium protein, unknown function 491 PBANKA_100420 conserved Plasmodium protein, unknown function 492 PBANKA_100460 conserved Plasmodium protein, unknown function 493 PBANKA_100470 conserved Plasmodium protein, unknown function 494 PBANKA_100520 conserved Plasmodium protein, unknown function 495 PBANKA_100530 conserved Plasmodium protein, unknown function 496 PBANKA_100540 conserved Plasmodium protein, unknown function 497 PBANKA_100570 conserved Plasmodium protein, unknown function 498 PBANKA_100640 conserved Plasmodium protein, unknown function 499 PBANKA_100690 conserved Plasmodium protein, unknown function 500 PBANKA_100710 conserved Plasmodium protein, unknown function 501 PBANKA_100760 conserved Plasmodium protein, unknown function 502 PBANKA_100790 conserved Plasmodium protein, unknown function 503 PBANKA_100840 conserved Plasmodium protein, unknown function 504 PBANKA_100910 conserved Plasmodium protein, unknown function 505 PBANKA_100920 conserved Plasmodium protein, unknown function 506 PBANKA_100970 conserved Plasmodium protein, unknown function 507 PBANKA_101040 conserved Plasmodium protein, unknown function 508 PBANKA_101210 conserved Plasmodium protein, unknown function 509 PBANKA_101300 conserved Plasmodium protein, unknown function 510 PBANKA_101470 conserved Plasmodium protein, unknown function 511 PBANKA_101540 conserved Plasmodium protein, unknown function 512 PBANKA_101730 conserved Plasmodium protein, unknown function 513 PBANKA_101760 conserved Plasmodium protein, unknown function 514 PBANKA_101870 conserved Plasmodium protein, unknown function 515 PBANKA_101880 conserved Plasmodium protein, unknown function 516 PBANKA_101890 conserved Plasmodium protein, unknown function 517 PBANKA_101920 conserved Plasmodium protein, unknown function 518 PBANKA_101935 conserved Plasmodium protein, unknown function 519 PBANKA_101990 conserved Plasmodium protein, unknown function 520 PBANKA_102050 conserved Plasmodium protein, unknown function 521 PBANKA_102120 conserved Plasmodium protein, unknown function 522 PBANKA_102210 conserved Plasmodium protein, unknown function 523 PBANKA_102400 conserved Plasmodium protein, unknown function 524 PBANKA_102560 conserved Plasmodium protein, unknown function 525 PBANKA_102630 conserved Plasmodium protein, unknown function 526 PBANKA_102640 conserved Plasmodium protein, unknown function 527 PBANKA_102900 conserved Plasmodium protein, unknown function 528 PBANKA_102910 conserved Plasmodium protein, unknown function 529 PBANKA_103020 conserved Plasmodium protein, unknown function 530 PBANKA_103080 conserved Plasmodium protein, unknown function 531 PBANKA_103120 conserved Plasmodium protein, unknown function 532 PBANKA_103140 conserved Plasmodium protein, unknown function 533 PBANKA_103160 conserved Plasmodium protein, unknown function 534 PBANKA_103220 conserved Plasmodium protein, unknown function 535 PBANKA_103290 conserved Plasmodium protein, unknown function 536 PBANKA_103300 conserved Plasmodium protein, unknown function 537 PBANKA_103310 conserved Plasmodium protein, unknown function 538 PBANKA_103350 conserved Plasmodium protein, unknown function 539 PBANKA_103400 conserved Plasmodium protein, unknown function 540 PBANKA_103420 conserved Plasmodium protein, unknown function 541 PBANKA_103450 conserved Plasmodium protein, unknown function 542 PBANKA_103740 conserved Plasmodium protein, unknown function 543 PBANKA_103810 conserved Plasmodium protein, unknown function 544 PBANKA_103920 conserved Plasmodium protein, unknown function 545 PBANKA_110200 conserved Plasmodium protein, unknown function 546 PBANKA_110210 conserved Plasmodium protein, unknown function 547 PBANKA_110530 conserved Plasmodium protein, unknown function 548 PBANKA_110600 conserved Plasmodium protein, unknown function 549 PBANKA_110990 conserved Plasmodium protein, unknown function 550 PBANKA_111000 conserved Plasmodium protein, unknown function 551 PBANKA_111080 conserved Plasmodium protein, unknown function 552 PBANKA_111150 conserved Plasmodium protein, unknown function 553 PBANKA_111210 conserved Plasmodium protein, unknown function 554 PBANKA_111290 conserved Plasmodium protein, unknown function 555 PBANKA_111320 conserved Plasmodium protein, unknown function 556 PBANKA_111360 conserved Plasmodium protein, unknown function 557 PBANKA_111390 conserved Plasmodium protein, unknown function 558 PBANKA_111480 conserved Plasmodium protein, unknown function 559 PBANKA_111680 conserved Plasmodium protein, unknown function 560 PBANKA_111690 conserved Plasmodium protein, unknown function 561 PBANKA_111720 conserved Plasmodium protein, unknown function 562 PBANKA_111920 conserved Plasmodium protein, unknown function 563 PBANKA_111930 conserved Plasmodium protein, unknown function 564 PBANKA_111940 conserved Plasmodium protein, unknown function 565 PBANKA_112000 conserved Plasmodium protein, unknown function 566 PBANKA_112010 conserved Plasmodium protein, unknown function 567 PBANKA_112030 conserved Plasmodium protein, unknown function 568 PBANKA_112310 conserved Plasmodium protein, unknown function 569 PBANKA_112320 conserved Plasmodium protein, unknown function 570 PBANKA_112410 conserved Plasmodium protein, unknown function 571 PBANKA_112430 conserved Plasmodium protein, unknown function 572 PBANKA_112440 conserved Plasmodium protein, unknown function 573 PBANKA_112590 conserved Plasmodium protein, unknown function 574 PBANKA_112710 conserved Plasmodium protein, unknown function 575 PBANKA_112800 conserved Plasmodium protein, unknown function 576 PBANKA_113030 conserved Plasmodium protein, unknown function 577 PBANKA_113130 conserved Plasmodium protein, unknown function 578 PBANKA_113150 conserved Plasmodium protein, unknown function 579 PBANKA_113220 conserved Plasmodium protein, unknown function 580 PBANKA_113370 conserved Plasmodium protein, unknown function 581 PBANKA_113610 conserved Plasmodium protein, unknown function 582 PBANKA_113800 conserved Plasmodium protein, unknown function 583 PBANKA_113860 conserved Plasmodium protein, unknown function 584 PBANKA_113990 conserved Plasmodium protein, unknown function 585 PBANKA_114010 conserved Plasmodium protein, unknown function 586 PBANKA_114140 conserved Plasmodium protein, unknown function 587 PBANKA_114180 conserved Plasmodium protein, unknown function 588 PBANKA_114260 conserved Plasmodium protein, unknown function 589 PBANKA_114310 conserved Plasmodium protein, unknown function 590 PBANKA_114320 conserved Plasmodium protein, unknown function 591 PBANKA_114330 conserved Plasmodium protein, unknown function 592 PBANKA_114380 conserved Plasmodium protein, unknown function 593 PBANKA_114420 conserved Plasmodium protein, unknown function 594 PBANKA_114430 conserved Plasmodium protein, unknown function 595 PBANKA_114440 conserved Plasmodium protein, unknown function 596 PBANKA_114490 conserved Plasmodium protein, unknown function 597 PBANKA_114500 conserved Plasmodium protein, unknown function 598 PBANKA_114510 conserved Plasmodium protein, unknown function 599 PBANKA_114550 conserved Plasmodium protein, unknown function 600 PBANKA_120180 conserved Plasmodium protein, unknown function 601 PBANKA_120250 conserved Plasmodium protein, unknown function 602 PBANKA_120410 conserved Plasmodium protein, unknown function 603 PBANKA_120450 conserved Plasmodium protein, unknown function 604 PBANKA_120460 conserved Plasmodium protein, unknown function 605 PBANKA_120470 conserved Plasmodium protein, unknown function 606 PBANKA_120520 conserved Plasmodium protein, unknown function 607 PBANKA_120570 conserved Plasmodium protein, unknown function 608 PBANKA_120600 conserved Plasmodium protein, unknown function 609 PBANKA_120760 conserved Plasmodium protein, unknown function 610 PBANKA_120940 conserved Plasmodium protein, unknown function 611 PBANKA_121050 conserved Plasmodium protein, unknown function 612 PBANKA_121140 conserved Plasmodium protein, unknown function 613 PBANKA_121200 conserved Plasmodium protein, unknown function 614 PBANKA_121210 conserved Plasmodium protein, unknown function 615 PBANKA_121290 conserved Plasmodium protein, unknown function 616 PBANKA_121440 conserved Plasmodium protein, unknown function 617 PBANKA_121720 conserved Plasmodium protein, unknown function 618 PBANKA_121740 conserved Plasmodium protein, unknown function 619 PBANKA_121750 conserved Plasmodium protein, unknown function 620 PBANKA_121850 conserved Plasmodium protein, unknown function 621 PBANKA_121860 conserved Plasmodium protein, unknown function 622 PBANKA_121870 conserved Plasmodium protein, unknown function 623 PBANKA_122050 conserved Plasmodium protein, unknown function 624 PBANKA_122080 conserved Plasmodium protein, unknown function 625 PBANKA_122130 conserved Plasmodium protein, unknown function 626 PBANKA_122140 conserved Plasmodium protein, unknown function 627 PBANKA_122270 conserved Plasmodium protein, unknown function 628 PBANKA_122340 conserved Plasmodium protein, unknown function 629 PBANKA_122490 conserved Plasmodium protein, unknown function 630 PBANKA_122540 conserved Plasmodium protein, unknown function 631 PBANKA_122710 conserved Plasmodium protein, unknown function 632 PBANKA_122730 conserved Plasmodium protein, unknown function 633 PBANKA_122830 conserved Plasmodium protein, unknown function 634 PBANKA_122870 conserved Plasmodium protein, unknown function 635 PBANKA_122960 conserved Plasmodium protein, unknown function 636 PBANKA_122990 conserved Plasmodium protein, unknown function 637 PBANKA_123060 conserved Plasmodium protein, unknown function 638 PBANKA_123070 conserved Plasmodium protein, unknown function 639 PBANKA_123280 conserved Plasmodium protein, unknown function 640 PBANKA_123370 conserved Plasmodium protein, unknown function 641 PBANKA_123470 conserved Plasmodium protein, unknown function 642 PBANKA_123550 conserved Plasmodium protein, unknown function 643 PBANKA_123620 conserved Plasmodium protein, unknown function 644 PBANKA_123680 conserved Plasmodium protein, unknown function 645 PBANKA_123690 conserved Plasmodium protein, unknown function 646 PBANKA_123730 conserved Plasmodium protein, unknown function 647 PBANKA_123810 conserved Plasmodium protein, unknown function 648 PBANKA_123850 conserved Plasmodium protein, unknown function 649 PBANKA_123870 conserved Plasmodium protein, unknown function 650 PBANKA_123890 conserved Plasmodium protein, unknown function 651 PBANKA_123970 conserved Plasmodium protein, unknown function 652 PBANKA_124030 conserved Plasmodium protein, unknown function 653 PBANKA_124120 conserved Plasmodium protein, unknown function 654 PBANKA_124150 conserved Plasmodium protein, unknown function 655 PBANKA_124240 conserved Plasmodium protein, unknown function 656 PBANKA_124320 conserved Plasmodium protein, unknown function 657 PBANKA_124410 conserved Plasmodium protein, unknown function 658 PBANKA_124420 conserved Plasmodium protein, unknown function 659 PBANKA_130110 conserved Plasmodium protein, unknown function 660 PBANKA_130160 conserved Plasmodium protein, unknown function 661 PBANKA_130490 conserved Plasmodium protein, unknown function 662 PBANKA_130560 conserved Plasmodium protein, unknown function 663 PBANKA_130660 conserved Plasmodium protein, unknown function 664 PBANKA_130850 conserved Plasmodium protein, unknown function 665 PBANKA_130930 conserved Plasmodium protein, unknown function 666 PBANKA_130940 conserved Plasmodium protein, unknown function 667 PBANKA_130960 conserved Plasmodium protein, unknown function 668 PBANKA_131120 conserved Plasmodium protein, unknown function 669 PBANKA_131150 conserved Plasmodium protein, unknown function 670 PBANKA_131160 conserved Plasmodium protein, unknown function 671 PBANKA_131240 conserved Plasmodium protein, unknown function 672 PBANKA_131280 conserved Plasmodium protein, unknown function 673 PBANKA_131290 conserved Plasmodium protein, unknown function 674 PBANKA_131310 conserved Plasmodium protein, unknown function 675 PBANKA_131450 conserved Plasmodium protein, unknown function 676 PBANKA_131520 conserved Plasmodium protein, unknown function 677 PBANKA_131530 conserved Plasmodium protein, unknown function 678 PBANKA_131670 conserved Plasmodium protein, unknown function 679 PBANKA_131760 conserved Plasmodium protein, unknown function 680 PBANKA_131900 conserved Plasmodium protein, unknown function 681 PBANKA_132000 conserved Plasmodium protein, unknown function 682 PBANKA_132060 conserved Plasmodium protein, unknown function 683 PBANKA_132100 conserved Plasmodium protein, unknown function 684 PBANKA_132110 conserved Plasmodium protein, unknown function 685 PBANKA_132210 conserved Plasmodium protein, unknown function 686 PBANKA_132220 conserved Plasmodium protein, unknown function 687 PBANKA_132250 conserved Plasmodium protein, unknown function 688 PBANKA_132260 conserved Plasmodium protein, unknown function 689 PBANKA_132300 conserved Plasmodium protein, unknown function 690 PBANKA_132310 conserved Plasmodium protein, unknown function 691 PBANKA_132390 conserved Plasmodium protein, unknown function 692 PBANKA_132420 conserved Plasmodium protein, unknown function 693 PBANKA_132430 conserved Plasmodium protein, unknown function 694 PBANKA_132510 conserved Plasmodium protein, unknown function 695 PBANKA_132660 conserved Plasmodium protein, unknown function 696 PBANKA_132708 conserved Plasmodium protein, unknown function 697 PBANKA_132740 conserved Plasmodium protein, unknown function 698 PBANKA_132750 conserved Plasmodium protein, unknown function 699 PBANKA_132850 conserved Plasmodium protein, unknown function 700 PBANKA_132960 conserved Plasmodium protein, unknown function 701 PBANKA_132990 conserved Plasmodium protein, unknown function 702 PBANKA_133050 conserved Plasmodium protein, unknown function 703 PBANKA_133150 conserved Plasmodium protein, unknown function 704 PBANKA_133290 conserved Plasmodium protein, unknown function 705 PBANKA_133360 conserved Plasmodium protein, unknown function 706 PBANKA_133670 conserved Plasmodium protein, unknown function 707 PBANKA_133730 conserved Plasmodium protein, unknown function 708 PBANKA_133790 conserved Plasmodium protein, unknown function 709 PBANKA_133800 conserved Plasmodium protein, unknown function 710 PBANKA_133880 conserved Plasmodium protein, unknown function 711 PBANKA_133920 conserved Plasmodium protein, unknown function 712 PBANKA_134050 conserved Plasmodium protein, unknown function 713 PBANKA_134080 conserved Plasmodium protein, unknown function 714 PBANKA_134090 conserved Plasmodium protein, unknown function 715 PBANKA_134170 conserved Plasmodium protein, unknown function 716 PBANKA_134210 conserved Plasmodium protein, unknown function 717 PBANKA_134230 conserved Plasmodium protein, unknown function 718 PBANKA_134250 conserved Plasmodium protein, unknown function 719 PBANKA_134260 conserved Plasmodium protein, unknown function 720 PBANKA_134270 conserved Plasmodium protein, unknown function 721 PBANKA_134340 conserved Plasmodium protein, unknown function 722 PBANKA_134350 conserved Plasmodium protein, unknown function 723 PBANKA_134370 conserved Plasmodium protein, unknown function 724 PBANKA_134390 conserved Plasmodium protein, unknown function 725 PBANKA_134460 conserved Plasmodium protein, unknown function 726 PBANKA_134510 conserved Plasmodium protein, unknown function 727 PBANKA_134520 conserved Plasmodium protein, unknown function 728 PBANKA_134550 conserved Plasmodium protein, unknown function 729 PBANKA_134580 conserved Plasmodium protein, unknown function 730 PBANKA_134640 conserved Plasmodium protein, unknown function 731 PBANKA_134690 conserved Plasmodium protein, unknown function 732 PBANKA_134730 conserved Plasmodium protein, unknown function 733 PBANKA_134880 conserved Plasmodium protein, unknown function 734 PBANKA_135050 conserved Plasmodium protein, unknown function 735 PBANKA_135240 conserved Plasmodium protein, unknown function 736 PBANKA_135250 conserved Plasmodium protein, unknown function 737 PBANKA_135270 conserved Plasmodium protein, unknown function 738 PBANKA_135300 conserved Plasmodium protein, unknown function 739 PBANKA_135310 conserved Plasmodium protein, unknown function 740 PBANKA_135360 conserved Plasmodium protein, unknown function 741 PBANKA_135370 conserved Plasmodium protein, unknown function 742 PBANKA_135420 conserved Plasmodium protein, unknown function 743 PBANKA_135460 conserved Plasmodium protein, unknown function 744 PBANKA_135670 conserved Plasmodium protein, unknown function 745 PBANKA_135680 conserved Plasmodium protein, unknown function 746 PBANKA_135760 conserved Plasmodium protein, unknown function 747 PBANKA_135790 conserved Plasmodium protein, unknown function 748 PBANKA_135890 conserved Plasmodium protein, unknown function 749 PBANKA_135940 conserved Plasmodium protein, unknown function 750 PBANKA_136020 conserved Plasmodium protein, unknown function 751 PBANKA_136040 conserved Plasmodium protein, unknown function 752 PBANKA_136140 conserved Plasmodium protein, unknown function 753 PBANKA_136170 conserved Plasmodium protein, unknown function 754 PBANKA_136330 conserved Plasmodium protein, unknown function 755 PBANKA_136340 conserved Plasmodium protein, unknown function 756 PBANKA_136410 conserved Plasmodium protein, unknown function 757 PBANKA_136440 conserved Plasmodium protein, unknown function 758 PBANKA_136450 conserved Plasmodium protein, unknown function 759 PBANKA_136490 conserved Plasmodium protein, unknown function 760 PBANKA_136530 conserved Plasmodium protein, unknown function 761 PBANKA_140180 conserved Plasmodium protein, unknown function 762 PBANKA_140190 conserved Plasmodium protein, unknown function 763 PBANKA_140210 conserved Plasmodium protein, unknown function 764 PBANKA_140330 conserved Plasmodium protein, unknown function 765 PBANKA_140420 conserved Plasmodium protein, unknown function 766 PBANKA_140450 conserved Plasmodium protein, unknown function 767 PBANKA_140600 conserved Plasmodium protein, unknown function 768 PBANKA_140860 conserved Plasmodium protein, unknown function 769 PBANKA_140920 conserved Plasmodium protein, unknown function 770 PBANKA_140950 conserved Plasmodium protein, unknown function 771 PBANKA_141150 conserved Plasmodium protein, unknown function 772 PBANKA_141200 conserved Plasmodium protein, unknown function 773 PBANKA_141320 conserved Plasmodium protein, unknown function 774 PBANKA_141370 conserved Plasmodium protein, unknown function 775 PBANKA_141380 conserved Plasmodium protein, unknown function 776 PBANKA_141540 conserved Plasmodium protein, unknown function 777 PBANKA_141620 conserved Plasmodium protein, unknown function 778 PBANKA_141640 conserved Plasmodium protein, unknown function 779 PBANKA_141760 conserved Plasmodium protein, unknown function 780 PBANKA_141900 conserved Plasmodium protein, unknown function 781 PBANKA_141960 conserved Plasmodium protein, unknown function 782 PBANKA_142280 conserved Plasmodium protein, unknown function 783 PBANKA_142290 conserved Plasmodium protein, unknown function 784 PBANKA_142300 conserved Plasmodium protein, unknown function 785 PBANKA_142420 conserved Plasmodium protein, unknown function 786 PBANKA_142430 conserved Plasmodium protein, unknown function 787 PBANKA_142470 conserved Plasmodium protein, unknown function 788 PBANKA_142520 conserved Plasmodium protein, unknown function 789 PBANKA_142540 conserved Plasmodium protein, unknown function 790 PBANKA_142550 conserved Plasmodium protein, unknown function 791 PBANKA_142580 conserved Plasmodium protein, unknown function 792 PBANKA_142660 conserved Plasmodium protein, unknown function 793 PBANKA_142710 conserved Plasmodium protein, unknown function 794 PBANKA_142970 conserved Plasmodium protein, unknown function 795 PBANKA_143020 conserved Plasmodium protein, unknown function 796 PBANKA_143030 conserved Plasmodium protein, unknown function 797 PBANKA_143110 conserved Plasmodium protein, unknown function 798 PBANKA_143160 conserved Plasmodium protein, unknown function 799 PBANKA_143180 conserved Plasmodium protein, unknown function 800 PBANKA_143410 conserved Plasmodium protein, unknown function 801 PBANKA_143450 conserved Plasmodium protein, unknown function 802 PBANKA_143630 conserved Plasmodium protein, unknown function 803 PBANKA_143690 conserved Plasmodium protein, unknown function 804 PBANKA_143770 conserved Plasmodium protein, unknown function 805 PBANKA_143780 conserved Plasmodium protein, unknown function 806 PBANKA_143810 conserved Plasmodium protein, unknown function 807 PBANKA_143900 conserved Plasmodium protein, unknown function 808 PBANKA_143910 conserved Plasmodium protein, unknown function 809 PBANKA_143930 conserved Plasmodium protein, unknown function 810 PBANKA_144030 conserved Plasmodium protein, unknown function 811 PBANKA_144060 conserved Plasmodium protein, unknown function 812 PBANKA_144090 conserved Plasmodium protein, unknown function 813 PBANKA_144150 conserved Plasmodium protein, unknown function 814 PBANKA_144230 conserved Plasmodium protein, unknown function 815 PBANKA_144360 conserved Plasmodium protein, unknown function 816 PBANKA_144370 conserved Plasmodium protein, unknown function 817 PBANKA_144520 conserved Plasmodium protein, unknown function 818 PBANKA_144550 conserved Plasmodium protein, unknown function 819 PBANKA_144590 conserved Plasmodium protein, unknown function 820 PBANKA_144640 conserved Plasmodium protein, unknown function 821 PBANKA_144710 conserved Plasmodium protein, unknown function 822 PBANKA_144750 conserved Plasmodium protein, unknown function 823 PBANKA_144780 conserved Plasmodium protein, unknown function 824 PBANKA_144810 conserved Plasmodium protein, unknown function 825 PBANKA_144900 conserved Plasmodium protein, unknown function 826 PBANKA_144950 conserved Plasmodium protein, unknown function 827 PBANKA_144970 conserved Plasmodium protein, unknown function 828 PBANKA_145080 conserved Plasmodium protein, unknown function 829 PBANKA_145090 conserved Plasmodium protein, unknown function 830 PBANKA_145150 conserved Plasmodium protein, unknown function 831 PBANKA_145170 conserved Plasmodium protein, unknown function 832 PBANKA_145180 conserved Plasmodium protein, unknown function 833 PBANKA_145190 conserved Plasmodium protein, unknown function 834 PBANKA_145200 conserved Plasmodium protein, unknown function 835 PBANKA_145220 conserved Plasmodium protein, unknown function 836 PBANKA_145230 conserved Plasmodium protein, unknown function 837 PBANKA_145270 conserved Plasmodium protein, unknown function 838 PBANKA_145470 conserved Plasmodium protein, unknown function 839 PBANKA_145540 conserved Plasmodium protein, unknown function 840 PBANKA_145550 conserved Plasmodium protein, unknown function 841 PBANKA_145740 conserved Plasmodium protein, unknown function 842 PBANKA_145760 conserved Plasmodium protein, unknown function 843 PBANKA_145770 conserved Plasmodium protein, unknown function 844 PBANKA_145810 conserved Plasmodium protein, unknown function 845 PBANKA_146060 conserved Plasmodium protein, unknown function 846 PBANKA_146120 conserved Plasmodium protein, unknown function 847 PBANKA_146130 conserved Plasmodium protein, unknown function 848 PBANKA_146270 conserved Plasmodium protein, unknown function 849 PBANKA_146360 conserved Plasmodium protein, unknown function 850 PBANKA_146380 conserved Plasmodium protein, unknown function conserved Plasmodium protein, unknown function 851 PBANKA_120630 (UIS11) conserved Plasmodium protein, unknown function 852 PBANKA_143600 (UIS27) 853 PBANKA_145490 conserved Plasmodium protein, unknown function (UIS8) conserved Plasmodium protein, unknown function, 854 PBANKA_090230 fragment conserved Plasmodium protein, unknown function, 855 PBANKA_031550 pseudogene 856 PBANKA_072080 conserved Plasmodium protein, unknwon function 857 PBANKA_133020 conserved Plasmodium protein, unknwon function 858 PBANKA_092890 conserved protein, unknown function 859 PBANKA_101240 conserved protein, unknown function 860 PBANKA_120340 conserved protein, unknown function 861 PBANKA_141950 conserved protein, unknown function 862 PBANKA_143350 conserved protein, unknown function 863 PBANKA_052450 conserved rodent malaria protein, unknown function 864 PBANKA_062310 conserved rodent malaria protein, unknown function 865 PBANKA_062315 conserved rodent malaria protein, unknown function 866 PBANKA_100050 conserved rodent malaria protein, unknown function 867 PBANKA_110086 conserved rodent malaria protein, unknown function 868 PBANKA_114580 conserved rodent malaria protein, unknown function 869 PBANKA_114590 conserved rodent malaria protein, unknown function 870 PBANKA_130290 copper transporter, putative 871 PBANKA_112200 coronin binding protein, putative 872 PBANKA_146410 coronin, putative 873 PBANKA_094340 CPW-WPC family protein, putative 874 PBANKA_144930 CPW-WPC family protein, putative 875 PBANKA_123320 cyclin, putative 876 PBANKA_140320 cyclin, putative 877 PBANKA_132170 cysteine proteinase, putative 878 PBANKA_081240 cysteine repeat modular protein 1 (CRMP1) 879 PBANKA_130080 cysteine repeat modular protein 4 (CRMP4) 880 PBANKA_103230 cytidine triphosphate synthetase, putative 881 PBANKA_140060 cytoadherence linked asexual protein, putative 882 PBANKA_081910 cytochrome b5, putative 883 PBANKA_143950 cytochrome c heme lyase, putative 884 PBANKA_060080 cytochrome c oxidase assembly protein, putative 885 PBANKA_130090 cytochrome c oxidase assembly protein, putative 886 PBANKA_082860 cytochrome c oxidase subunit, putative 887 PBANKA_082880 cytochrome c oxidase, putative 888 PBANKA_060260 cytochrome c1 heme lyase, putative 889 PBANKA_141020 cytochrome c2 precursor,putative 890 PBANKA_050450 cytoplasmic dynein intermediate chain, putative 891 PBANKA_100400 cytosolic glyoxalase II, putative 892 PBANKA_101350 cytosolic preribosomal GTPase, putative 893 PBANKA_061880 DEAD box helicase, putative 894 PBANKA_112970 DEAD/DEAH box ATP-dependent RNA helicase, putative 895 PBANKA_130300 DEAD/DEAH helicase, putative 896 PBANKA_123630 DEAD-box subfamily ATP-dependent helicase, putative 897 PBANKA_070420 dehydrodolichyl diphosphate synthetase, putative 898 PBANKA_130410 delta-aminolevulinic acid dehydratase, putative 899 PBANKA_140110 deoxyhypusine hydroxylase, putative 900 PBANKA_103000 deoxyhypusine synthase, putative 901 PBANKA_130760 dephospho-CoA kinase, putative 902 PBANKA_041200 DER1-like protein, putative 903 PBANKA_133180 derlin-2, putative 904 PBANKA_051200 DHHC-type zinc finger protein, putative 905 PBANKA_070670 dicarboxylate/tricarboxylate carrier, putative (DTC) dihydrofolate synthase/folylpolyglutamate synthase, 906 PBANKA_134000 putative 907 PBANKA_050500 dihydrolipoamide acyltransferase, putative 908 PBANKA_144690 dihydrolipoamide dehydrogenase, putative (mLipDH) 909 PBANKA_010210 dihydroorotate dehydrogenase, putative 910 PBANKA_081970 dihydrouridine synthase, putative 911 PBANKA_102690 dimethyladenosine transferase, putative 912 PBANKA_146070 dipeptidyl peptidase 2, putative (DPAP2) 913 PBANKA_102890 diphthamide synthesis protein, putative 914 PBANKA_120730 diphthine synthase, putative 915 PBANKA_133580 disulfide-isomerase, putative 916 PBANKA_020740 DNA binding protein, putative 917 PBANKA_081950 DNA helicase, putative 918 PBANKA_112420 DNA polymerase 1, putative 919 PBANKA_061320 DNA polymerase alpha, putative 920 PBANKA_050130 DNA polymerase delta catalytic subunit, putative 921 PBANKA_020560 DNA repair exonuclease, putative 922 PBANKA_071830 DNA replication licensing factor, putative 923 PBANKA_135920 DNA/RNA-binding protein Alba 2, putative (ALBA2) 924 PBANKA_120440 DNA/RNA-binding protein Alba 3, putative (ALBA3) 925 PBANKA_094020 dna2/nam7 helicase family member, putative 926 PBANKA_120860 DNA2/NAM7 helicase, putative 927 PBANKA_133040 DNA-3-methyladenine glycosylase, putative 928 PBANKA_092300 DNA-dependent RNA polymerase, putative 929 PBANKA_101910 DNA-directed DNA polymerase, putative DNA-directed RNA polymerase 3 largest subunit, 930 PBANKA_134400 putative DNA-directed RNA polymerase II 16 kDa subunit, 931 PBANKA_030320 putative 932 PBANKA_082390 DNA-directed RNA polymerase II, putative 933 PBANKA_040190 DNA-directed RNA polymerase subunit I, putative 934 PBANKA_133590 DNA-directed RNA polymerase, alpha subunit, putative 935 PBANKA_090580 DnaJ protein, putative 936 PBANKA_092200 DnaJ protein, putative 937 PBANKA_111990 DnaJ protein, putative 938 PBANKA_112780 DnaJ protein, putative 939 PBANKA_120380 DnaJ protein, putative 940 PBANKA_120390 DnaJ protein, putative 941 PBANKA_133640 DnaJ protein, putative 942 PBANKA_141730 DnaJ/SEC63 protein, putative dolichyl-diphosphooligosaccharide--protein- 943 PBANKA_082050 glycosyltransferase, putative 944 PBANKA_133270 duffy-binding protein 945 PBANKA_021400 dynein heavy chain, putative 946 PBANKA_060120 dynein heavy chain, putative 947 PBANKA_082830 dynein light chain, putative 948 PBANKA_041490 dynein light intermediate chain 2, putative 949 PBANKA_101030 dynein-related AAA-type ATPase, putative 950 PBANKA_020160 early transcribed membrane protein (ETRAMP) 951 PBANKA_051700 early transcribed membrane protein (ETRAMP) 952 PBANKA_140080 early transcribed membrane protein 13 (UIS3) 953 PBANKA_040560 EB1 homolog, putative 954 PBANKA_112220 EGF-like membrane protein, putative 955 PBANKA_040280 EH (Eps15 homology) protein, putative 956 PBANKA_121890 elongation factor 1 (EF-1), putative 957 PBANKA_113330 elongation factor 1 alpha (EF-1alpha) 958 PBANKA_113340 elongation factor 1 alpha (EF-1alpha) 959 PBANKA_081420 elongation factor 1-beta, putative 960 PBANKA_135200 elongation factor 1-gamma, putative 961 PBANKA_131480 elongation factor 2, putative 962 PBANKA_144770 elongation factor G, putative (EF-G) 963 PBANKA_122950 endonuclease III homologue, putative endoplasmic reticulum-resident calcium binding protein, 964 PBANKA_093840 putative 965 PBANKA_143730 endoplasmin homolog precursor, putative 966 PBANKA_145680 endosome sorting protein (SNF7 homologue), putative 967 PBANKA_052060 enhancer of rudimentary homolog, putative 968 PBANKA_121430 enolase, putative (ENO) 969 PBANKA_122980 enoyl-acyl carrier reductase (FABI) 970 PBANKA_093160 ER membrane protein Sec12, putative (SEC12) 971 PBANKA_092370 ethanolamine kinase, putative 972 PBANKA_136050 ethanolamine-phosphate cytidylyltransferase (ECT) 973 PBANKA_061080 eukaryotic initiation factor 2a, putative eukaryotic translation initation factor 4 gamma, putative 974 PBANKA_141130 (EIF4G) eukaryotic translation initiation factor 2 alpha subunit, 975 PBANKA_021210 putative 976 PBANKA_146350 eukaryotic translation initiation factor 2b, putative eukaryotic translation initiation factor 3 subunit 10, 977 PBANKA_142870 putative eukaryotic translation initiation factor 3 subunit 5, 978 PBANKA_081930 putative eukaryotic translation initiation factor 3 subunit 7, 979 PBANKA_120610 putative eukaryotic translation initiation factor 5a, putative 980 PBANKA_060320 (EIF5A) 981 PBANKA_061450 eukaryotic translation initiation factor subunit, putative 982 PBANKA_062250 exonuclease I, putative 983 PBANKA_135110 exoribonuclease, putative 984 PBANKA_100780 exosome complex component RRP4, putative (RRP4) 985 PBANKA_133430 exported protein 2, putative (EXP2) FAD-dependent glycerol-3-phosphate dehydrogenase, 986 PBANKA_040480 putative 987 PBANKA_090160 farnesyltransferase beta subunit, putative fatty acid elongation protein, GNS1/SUR4 family, 988 PBANKA_020430 putative, pseudogene 989 PBANKA_131930 ferlin, putative 990 PBANKA_141660 ferredoxin, putative 991 PBANKA_112210 ferredoxin--NADP reductase, putative 992 PBANKA_061790 ferrodoxin reductase-like protein, putative 993 PBANKA_103510 fibrillarin, putative (NOP1) 994 PBANKA_082410 flavodoxin-like protein 995 PBANKA_123750 G10 protein, putative geranylgeranyl pyrophosphate synthase, putative 996 PBANKA_091980 (GGPPS) 997 PBANKA_081580 GINS complex subunit Psf3, putative glideosome associated protein with multiple membrane 998 PBANKA_133890 spans 1, putative (GAPM1) glideosome associated protein with multiple membrane 999 PBANKA_052390 spans 2, putative (GAPM2) 1000 PBANKA_143760 glideosome-associated protein 45, putative 1001 PBANKA_145730 glucose inhibited division protein a homologue, putative glucose-6-phosphate dehydrogenase-6- 1002 PBANKA_131750 phosphogluconolactonase (G6PD-6PGL) 1003 PBANKA_113350 glutamate - tRNA ligase, putative 1004 PBANKA_136200 glutamate - tRNA ligase, putative 1005 PBANKA_134660 glutaminyl-tRNA synthetase, putative 1006 PBANKA_071810 glutamyl-tRNA(Gln) amidotransferase subunit A, putative 1007 PBANKA_040470 glutaredoxin 1, putative (GRX1) 1008 PBANKA_102390 glutathione s-transferase, putative 1009 PBANKA_111180 glutathione synthetase (GS) 1010 PBANKA_132640 glyceraldehyde-3-phosphate dehydrogenase, putative 1011 PBANKA_142850 glycerol-3-phosphate acyltransferase, putative 1012 PBANKA_093290 glycerol-3-phosphate dehydrogenase, putative 1013 PBANKA_091550 glycine cleavage system H protein, putative 1014 PBANKA_093390 glyoxalase I, putative 1015 PBANKA_121100 GMP synthetase, putative (GMPS) 1016 PBANKA_050160 golgi re-assembly stacking protein, putative (GRASP) 1017 PBANKA_060930 GPI mannosyltransferase I, putative 1018 PBANKA_070190 GPI-anchored micronemal antigen, putative (GAMA) 1019 PBANKA_124020 G-protein coupled receptor, putative 1020 PBANKA_093340 GTPase activating protein, putative 1021 PBANKA_122570 GTPase activating protein, putative 1022 PBANKA_111310 GTP-binding protein, putative 1023 PBANKA_040180 HAD superfamily protein, putative 1024 PBANKA_031000 heat shock 40 kDa protein, putative 1025 PBANKA_121400 heat shock protein 60, putative 1026 PBANKA_135720 heat shock protein 70 (hsp70), putative 1027 PBANKA_081890 heat shock protein 70, putative 1028 PBANKA_121930 heat shock protein 70, putative (HSP70-z) 1029 PBANKA_080570 heat shock protein 90, putative (HSP90) 1030 PBANKA_060990 heat shock protein DNAJ homologue Pfj4, putative 1031 PBANKA_112680 HECT-domain (ubiquitin-transferase), putative 1032 PBANKA_081110 helicase, putative 1033 PBANKA_111380 helicase, putative (UIS26) 1034 PBANKA_131060 heme detoxification protein, putative 1035 PBANKA_131910 hemolysin, putative 1036 PBANKA_143610 heterochromatin protein 1, putative (HP1) 1037 PBANKA_071290 high mobility group protein, putative (HMGB2) 1038 PBANKA_130890 histidine -- tRNA ligase, putative 1039 PBANKA_061190 histidine triad protein, putative 1040 PBANKA_070730 histone acetyltransferase GCN5, putative (GCN5) 1041 PBANKA_110620 histone deacetylase, putative 1042 PBANKA_121760 histone H2A variant, putative (H2A.Z) 1043 PBANKA_111700 histone H2A, putative (H2A) 1044 PBANKA_142060 histone H2B, putative 1045 PBANKA_010880 histone H3, putative 1046 PBANKA_111710 histone H3, putative (H3.3) 1047 PBANKA_142600 histone-arginine methyltransferase, putative (CARM1) 1048 PBANKA_052160 holo-(acyl-carrier protein) synthase, putative 1049 PBANKA_061090 HSP40, subfamily A, putative 1050 PBANKA_144100 hydrolase/phosphatase, putative 1051 PBANKA_121230 initiation factor 2 subunit family, putative 1052 PBANKA_040260 inner membrane complex protein 1a (IMC1a) 1053 PBANKA_144980 inorganic pyrophosphatase, putative 1054 PBANKA_093600 inositol-5 phosphatase, putative intra-erythrocytic P. berghei-induced structures protein 1 1055 PBANKA_136550 (IBIS1) 1056 PBANKA_030460 iron-sulfur assembly protein, putative isocitrate dehydrogenase (NADP), mitochondrial 1057 PBANKA_135860 precursor, putative (IDH) 1058 PBANKA_145880 kinesin, putative 1059 PBANKA_090250 kinesin-like protein, putative 1060 PBANKA_060950 kinesin-related protein, putative 1061 PBANKA_061380 large ribosomal subunit assembling factor, putative 1062 PBANKA_133010 large ribosomal subunit assembling protein, putative large ribosomal subunit nuclear export factor, putative 1063 PBANKA_132140 (UIS20) 1064 PBANKA_050420 large subunit rRNA processing RRM protein, putative 1065 PBANKA_130990 leucine aminopeptidase, putative 1066 PBANKA_130360 leucine carboxyl methyltransferase, putative 1067 PBANKA_090270 leucine-rich repeat protein (LRR10) 1068 PBANKA_101250 leucine-rich repeat protein (LRR5) 1069 PBANKA_011050 leucine-rich repeat protein (LRR6) 1070 PBANKA_010110 liver merozoite formation protein (PALM) 1071 PBANKA_102460 liver specific protein 1 (LISP1) 1072 PBANKA_134010 L-lactate dehydrogenase (LDH) long chain polyunsaturated fatty acid elongation enzyme, 1073 PBANKA_010470 putative 1074 PBANKA_031180 long-chain acyl-CoA synthase, putative 1075 PBANKA_020130 lysophospholipase, putative 1076 PBANKA_122020 lysophospholipase, putative 1077 PBANKA_144400 macrophage migration inhibitory factor (MIF) 1078 PBANKA_111630 malate:quinone oxidoreductase, putative malonyl CoA-acyl carrier protein transacylase precursor, 1079 PBANKA_141050 putative 1080 PBANKA_120200 membrane skeletal protein, putative 1081 PBANKA_081570 membrane transporter, putative 1082 PBANKA_071960 memo-like protein 1083 PBANKA_090130.2 merozoite adhesive erythrocytic binding protein 1084 PBANKA_083100 merozoite surface protein 1 (MSP1) 1085 PBANKA_111960 merozoite surface protein 10, putative (MSP10) 1086 PBANKA_134910 merozoite surface protein 7 (MSP7) 1087 PBANKA_113140 metacaspase 1 (MCA1) 1088 PBANKA_130230 metacaspase-like protein 1089 PBANKA_102650 metacaspase-like protein (MCA3) 1090 PBANKA_120780 metallopeptidase, putative 1091 PBANKA_101020 methionine aminopeptidase, type II, putative 1092 PBANKA_051870 methionine-tRNA ligase, putative 1093 PBANKA_120330 methionine-tRNA ligase, putative 1094 PBANKA_082600 methyltransferase, putative 1095 PBANKA_092110 methyltransferase, putative 1096 PBANKA_113090 methyltransferase, putative 1097 PBANKA_133940 microfibril-associated protein homologue, putative microtubule-associated protein ytm1 homologue, 1098 PBANKA_112930 putative minchromosome maintenance (MCM) complex subunit, 1099 PBANKA_061020 putative (MCM5) 1100 PBANKA_020510 mitochondrial carrier protein, putative 1101 PBANKA_145500 mitochondrial carrier protein, putative 1102 PBANKA_113250 mitochondrial inner membrane translocase, putative 1103 PBANKA_060110 mitochondrial phosphate carrier protein, putative 1104 PBANKA_102180 mitochondrial protein import protein TIM13, putative 1105 PBANKA_122150 mitochondrial ribosomal protein L1 precursor, putative 1106 PBANKA_030900 mitochondrial ribosomal protein L12 precursor, putative 1107 PBANKA_041390 mitochondrial ribosomal protein L27 precursor, putative 1108 PBANKA_145860 mitochondrial ribosomal protein L3 precursor, putative 1109 PBANKA_135290 mitochondrial ribosomal protein L49 precursor, putative 1110 PBANKA_131110 mitochondrial ribosomal protein S14 precursor, putative 1111 PBANKA_061000 mitochondrial ribosomal protein S18 precursor, putative 1112 PBANKA_051130 mitochondrial ribosomal protein S22 precursor, putative 1113 PBANKA_091160 mitochondrial ribosomal protein S9 precursor, putative 1114 PBANKA_122690 mitogen-activated protein kinase organizer 1, putative 1115 PBANKA_135910 MOG1 homologue, putative 1116 PBANKA_082720 monocarboxylase transporter, putative 1117 PBANKA_021360 mRNA (N6-adenosine)-methyltransferase, putative 1118 PBANKA_083380 mRNA processing protein, putative 1119 PBANKA_134920 MSP7-like protein (MSRP1) 1120 PBANKA_134900 MSP7-like protein (MSRP2) 1121 PBANKA_141430 Myb1 protein, putative 1122 PBANKA_111140 myo-inositol 1-phosphate synthase, putative 1123 PBANKA_135570 myosin A (MyoA) 1124 PBANKA_144450 myosin D, putative (MyoD) 1125 PBANKA_090850 myosin heavy chain subunit, putative 1126 PBANKA_134410 myosin, putative 1127 PBANKA_011220 myosin-like protein, putative 1128 PBANKA_040750 N2227-like protein, putative 1129 PBANKA_136350 N6-adenine-specific methylase, putative N-acetylglucosaminylphosphatidylinositol deacetylase, 1130 PBANKA_112360 putative 1131 PBANKA_061180 N-acetyltransferase, putative 1132 PBANKA_120170 N-acetyltransferase, putative 1133 PBANKA_100950 NAD(P)H-dependent glutamate synthase, putative NADP-specific glutamate dehydrogenase, putative 1134 PBANKA_102620 (GDH1) NADP-specific glutamate dehydrogenase, putative 1135 PBANKA_101400 (GDH2) nascent polypeptide associated complex alpha chain, 1136 PBANKA_112070 putative 1137 PBANKA_111570 Ndc80 homolog, putative 1138 PBANKA_134280 nicotinic acid mononucleotide adenyltransferase 1139 PBANKA_111550 nif-like protein, putative 1140 PBANKA_124070 NIMA related kinase 2 (NEK2) 1141 PBANKA_060060 NIMA related kinase 3, putative (NEK3) 1142 PBANKA_061670 NIMA related kinase 4 (NEK4) 1143 PBANKA_102980 N-myristoyltransferase, putative 1144 PBANKA_102550 NOT family protein, putative 1145 PBANKA_020830 novel putative transporter 1 (NPT1) 1146 PBANKA_135060 nuclear movement protein, putative 1147 PBANKA_092350 nuclear preribosomal assembly protein, putative 1148 PBANKA_103030 nuclear transport factor 2, putative 1149 PBANKA_011120 nucleolar GTP-binding protein 1, putative 1150 PBANKA_124110 nucleolar Jumonji domain interacting protein, putative 1151 PBANKA_051240 nucleolar preribosomal assembly protein, putative 1152 PBANKA_051250 nucleolar preribosomal assembly protein, putative 1153 PBANKA_071240 nucleolar preribosomal assembly protein, putative 1154 PBANKA_071480 nucleolar preribosomal assembly protein, putative 1155 PBANKA_090310 nucleolar preribosomal assembly protein, putative nucleolar preribosomal associated cytoplasmic ATPase, 1156 PBANKA_136260 putative 1157 PBANKA_124340 nucleolar preribosomal GTPase, putative 1158 PBANKA_083190 nucleolar protein Nop52, putative 1159 PBANKA_136010 nucleoside transporter 1 (NT1) 1160 PBANKA_020990 nucleoside transporter, putative 1161 PBANKA_123640 nucleotide binding protein, putative 1162 PBANKA_134720 nucleotidyltransferase, putative 1163 PBANKA_144760 nucleotidyltransferase, putative 1164 PBANKA_121810 oocyst capsule protein (Cap380) 1165 PBANKA_010740 ornithine aminotransferase, putative (OAT) 1166 PBANKA_082400 OTU-like cysteine protease, putative 1167 PBANKA_103340 oxidoreductase, putative 1168 PBANKA_020920 parasite-infected erythrocyte surface protein (PIESP15) 1169 PBANKA_082490 patatin-like phospholipase, putative 1170 PBANKA_020020 Pb-fam-1 protein 1171 PBANKA_020060 Pb-fam-1 protein 1172 PBANKA_021490 Pb-fam-1 protein 1173 PBANKA_060040 Pb-fam-1 protein 1174 PBANKA_062340 Pb-fam-1 protein 1175 PBANKA_062350 Pb-fam-1 protein 1176 PBANKA_090100 Pb-fam-1 protein 1177 PBANKA_110090 Pb-fam-1 protein 1178 PBANKA_110100 Pb-fam-1 protein 1179 PBANKA_124610 Pb-fam-1 protein 1180 PBANKA_136560 Pb-fam-1 protein 1181 PBANKA_020120 Pb-fam-1 protein, pseudogene 1182 PBANKA_021555 Pb-fam-1 protein, pseudogene 1183 PBANKA_040080 Pb-fam-1 protein, pseudogene 1184 PBANKA_062345 Pb-fam-1 protein, pseudogene 1185 PBANKA_100650 peptidase, M22 family, putative 1186 PBANKA_093220 peptidyl-prolyl cis-trans isomerase, putative 1187 PBANKA_121650 peptidyl-prolyl cis-trans isomerase, putative (CYP19A) 1188 PBANKA_122720 peptidyl-prolyl cis-trans isomerase, putative (CYP81) 1189 PBANKA_100480 peptidyl-tRNA hydrolase, putative 1190 PBANKA_051140 peroxiredoxin, putative (nPrx) 1191 PBANKA_092650 petidase, M16 family, putative 1192 PBANKA_040830 phd finger protein, putative 1193 PBANKA_090720 phd finger protein, putative 1194 PBANKA_144670 phenylalanyl-tRNA synthetase alpha chain, putative 1195 PBANKA_094290 phenylalanyl-tRNA synthetase beta chain, putative 1196 PBANKA_121110 phosphatase, putative 1197 PBANKA_143400 phosphate translocator, putative 1198 PBANKA_040930 phosphatidylinositol 3- and 4-kinase, putative phosphatidylinositol N- acetylglucosaminyltransferase 1199 PBANKA_083610 subunit P, putative phosphatidylinositol N- acetylglucosaminyltransferase, 1200 PBANKA_081210 putative 1201 PBANKA_082870 phosphatidylserine decarboxylase, putative 1202 PBANKA_133370 phosphodiesterase delta (PDEdelta) 1203 PBANKA_141990 phosphodiesterase gamma (PDEgamma) 1204 PBANKA_135590 phosphoenolpyruvate carboxykinase, putative (PEPCK) 1205 PBANKA_082340 phosphoglycerate kinase, putative (PGK) 1206 PBANKA_092810 phosphoglycerate mutase, putative (PGM1) 1207 PBANKA_112810 phospholipase (PL) 1208 PBANKA_030620 phospholipase A2, putative 1209 PBANKA_062320 phospholipase, putative 1210 PBANKA_142310 phospholipase, putative 1211 PBANKA_010030 phospholipase, putative, pseudogene 1212 PBANKA_081520 phospholipid or glycerol acyltransferase, putative 1213 PBANKA_071470 phosphopantothenoylcysteine decarboxylase, putative 1214 PBANKA_101460 phosphotyrosyl phosphatase activator, putative 1215 PBANKA_020460 photosensitized INA-labeled protein 1, putative 1216 PBANKA_133870 plasmepsin V, putative (PMV) 1217 PBANKA_122250 plasmepsin X 1218 PBANKA_010020 Plasmodium exported protein, unknown function 1219 PBANKA_020080 Plasmodium exported protein, unknown function 1220 PBANKA_020150 Plasmodium exported protein, unknown function 1221 PBANKA_021470 Plasmodium exported protein, unknown function 1222 PBANKA_021560 Plasmodium exported protein, unknown function 1223 PBANKA_031630 Plasmodium exported protein, unknown function 1224 PBANKA_070060 Plasmodium exported protein, unknown function 1225 PBANKA_070070 Plasmodium exported protein, unknown function 1226 PBANKA_083640 Plasmodium exported protein, unknown function 1227 PBANKA_110120 Plasmodium exported protein, unknown function 1228 PBANKA_114540 Plasmodium exported protein, unknown function 1229 PBANKA_114620 Plasmodium exported protein, unknown function 1230 PBANKA_120060 Plasmodium exported protein, unknown function 1231 PBANKA_120710 Plasmodium exported protein, unknown function 1232 PBANKA_122900 Plasmodium exported protein, unknown function 1233 PBANKA_124590 Plasmodium exported protein, unknown function 1234 PBANKA_124592 Plasmodium exported protein, unknown function 1235 PBANKA_146500 Plasmodium exported protein, unknown function Plasmodium exported protein, unknown function, 1236 PBANKA_021460 fragment Plasmodium exported protein, unknown function, 1237 PBANKA_021455 pseudogene 1238 PBANKA_010520 polypyrimidine tract binding protein, putative 1239 PBANKA_060800 porphobilinogen deaminase, putative 1240 PBANKA_011090 PP-loop family protein, putative 1241 PBANKA_082010 PPPDE peptidase, putative 1242 PBANKA_102580 prefoldin subunit 2, putative 1243 PBANKA_040910 pre-mRNA splicing factor, putative 1244 PBANKA_082360 pre-mRNA splicing factor, putative 1245 PBANKA_103930 pre-mRNA splicing factor, putative 1246 PBANKA_143530 pre-mRNA splicing factor, putative 1247 PBANKA_040680 pre-mRNA-processing factor 19, putative (PRPF19) pre-mRNA-splicing factor ATP-dependent RNA helicase 1248 PBANKA_144630 PRP2, putative (PRP2) pre-mRNA-splicing factor ATP-dependent RNA helicase 1249 PBANKA_081860 PRP43, putative (PRP43) 1250 PBANKA_010860 Pre-mRNA-splicing factor SLU7, putative (SLU7) 1251 PBANKA_052290 pre-mRNA-splicing helicase BRR2, putative (BRR2) 1252 PBANKA_083070 procollagen lysine 5-dioxygenase, putative 1253 PBANKA_083300 profilin, putative (PFN) 1254 PBANKA_121310 prohibitin, putative 1255 PBANKA_113790 proliferating cell nuclear antigen, putative (PCNA) 1256 PBANKA_101630 proliferation-associated protein 2g4, putative 1257 PBANKA_030360 proteasome 26S regulatory subunit, putative 1258 PBANKA_072030 proteasome regulatory component, putative 1259 PBANKA_123310 proteasome subunit beta type 1, putative 1260 PBANKA_070280 protein disulfide isomerase 1261 PBANKA_092660 protein GCN20, putative 1262 PBANKA_071330 protein kinase c inhibitor-like protein, putative 1263 PBANKA_090110 protein kinase, putative 1264 PBANKA_094010 protein kinase, putative 1265 PBANKA_101620 protein kinase, putative 1266 PBANKA_110320 protein kinase, putative 1267 PBANKA_122880 protein kinase, putative 1268 PBANKA_141450 protein kinase, putative 1269 PBANKA_144560 protein kinase, putative 1270 PBANKA_092700 protein kinase, putative (TKL2) 1271 PBANKA_091340 protein phosphatase 2C, putative 1272 PBANKA_051550 protein phosphatase inhibitor, putative 1273 PBANKA_132950 protein serine/threonine phosphatase, putative 1274 PBANKA_070800 protein transport protein Sec23, putative (SEC23) 1275 PBANKA_093430 protein tyrosine phosphatase, putative 1276 PBANKA_122600 pseudouridylate synthase, putative 1277 PBANKA_080630 P-type ATPase, putative 1278 PBANKA_111300 purine nucleotide phosphorylase, putative 1279 PBANKA_123080 pyridoxal kinase-like protein, putative 1280 PBANKA_112020 pyridoxine biosynthesis protein PDX1, putative (PDX1) 1281 PBANKA_113420 pyrroline carboxylate reductase, putative 1282 PBANKA_131010 pyruvate dehydrogenase E1 beta subunit, putative pyruvate dehydrogenase E1 component, alpha subunit, 1283 PBANKA_092380 putative 1284 PBANKA_052000 pyruvate kinase 2, putative 1285 PBANKA_112560 pyruvate kinase, putative 1286 PBANKA_134680 Qa-SNARE protein, putative 1287 PBANKA_061510 queuine tRNA-ribosyltransferase, putative 1288 PBANKA_135410 Rab GTPase 11b 1289 PBANKA_145620 rab specific GDP dissociation inhibitor, putative (rabGDI) 1290 PBANKA_111350 Rab1a, putative 1291 PBANKA_140910 Rab5b, GTPase, putative 1292 PBANKA_090410 Rab6 1293 PBANKA_103530 radical SAM protein, putative 1294 PBANKA_072170 ran binding protein 1, putative 1295 PBANKA_051380 RAP protein, putative 1296 PBANKA_111620 ras GTPAse, putative 1297 PBANKA_070390 receptor for activated C kinase, putative (RACK) 1298 PBANKA_072070 regulator of chromosome condensation, putative 1299 PBANKA_121610 regulator of initiation factor 2, putative 1300 PBANKA_134290 regulator of nonsense transcripts 3B, putative (UPF3B) 1301 PBANKA_031600 replication factor C subunit 1, putative 1302 PBANKA_031470 replication factor C, subunit 2, putative 1303 PBANKA_070090 reticulocyte-binding protein, putative 1304 PBANKA_121510 Rh5 interacting protein, putative (RIPR) 1305 PBANKA_060500 rhodanese like protein, putative 1306 PBANKA_070270 rhomboid protease, putative 1307 PBANKA_111470 rhomboid protease, putative 1308 PBANKA_041600 RhopH3, putative 1309 PBANKA_146490 rhoptry neck protein 3, putative (RON3) 1310 PBANKA_071310 rhoptry neck protein 5, putative (RON5) 1311 PBANKA_031170 rhoptry neck protein 6, putative (RON6) 1312 PBANKA_010040 rhoptry protein, putative 1313 PBANKA_114230 rhoptry protein, putative 1314 PBANKA_133030 rhoptry protein, putative 1315 PBANKA_103210 rhoptry-associated protein 1, putative (RAP1) 1316 PBANKA_110140 rhoptry-associated protein 2/3 (RAP2/3) 1317 PBANKA_134240 ribonuclease P protein subunit rpr, putative 1318 PBANKA_122010 ribonucleases p/mrp protein subunit, putative 1319 PBANKA_111750 ribosomal protein L27a, putative 1320 PBANKA_132400 ribosomal protein L29, putative 1321 PBANKA_080400 ribosomal protein, L37e, putative ribosome associated membrane protein RAMP4, 1322 PBANKA_031580 putative 1323 PBANKA_114350 ribosome biogenesis protein MRT4, putative 1324 PBANKA_052180 ribosome recycling factor, putative 1325 PBANKA_030570 ribosome-recycling factor, putative (RRF) 1326 PBANKA_031190 RING zinc finger protein, putative 1327 PBANKA_080330 RNA helicase, putative 1328 PBANKA_102430 RNA helicase, putative 1329 PBANKA_122350 RNA helicase, putative 1330 PBANKA_130900 RNA helicase, putative 1331 PBANKA_091880 RNA methyltransferase, putative 1332 PBANKA_110900 RNA polymerase I, putative 1333 PBANKA_102750 RNA polymerase small subunit, putative 1334 PBANKA_094220 RNA polymerase subunit, putative 1335 PBANKA_102190 RNA polymerase subunit, putative 1336 PBANKA_111100 RNA pseudouridylate synthase, putative, fragment 1337 PBANKA_070740 RNA-binding protein, putative 1338 PBANKA_071790 RNA-binding protein, putative 1339 PBANKA_082480 RNA-binding protein, putative 1340 PBANKA_083000 RNA-binding protein, putative 1341 PBANKA_103630 RNA-binding protein, putative 1342 PBANKA_101530 rRNA (adenosine-2'-O-)-methyltransferase, putative 1343 PBANKA_094090 RuvB DNA helicase, putative 1344 PBANKA_070750 RWD domain-containing protein, putative 1345 PBANKA_082310 S-adenosylmethionine synthetase, putative 1346 PBANKA_123700 S-adenosylmethionine-dependent methyltransferase, putative 1347 PBANKA_140480 SAM dependent methyltransferase, putative schizont membrane associated cytoadherence protein 1348 PBANKA_010060 (SMAC) 1349 PBANKA_112520 Sec14 protein, putative 1350 PBANKA_100280 Sec24-like protein, putative 1351 PBANKA_135900 sec61 alpha subunit, putative 1352 PBANKA_040780 SECIS-binding protein 2, putative (SBP2) 1353 PBANKA_103780 secreted ookinete adhesive protein (SOAP) 1354 PBANKA_061920 secreted ookinete protein, putative (PSOP1) 1355 PBANKA_041080 SEL-1 like protein 1356 PBANKA_141210 septum formation protein MAF homologue, putative 1357 PBANKA_100300 sequestrin, putative 1358 PBANKA_102700 serine C-palmitoyltransferase, putative 1359 PBANKA_030510 serine repeat antigen 1 (SERA1) 1360 PBANKA_030500 serine repeat antigen 2 (SERA2) 1361 PBANKA_030490 serine repeat antigen 3 (SERA3) 1362 PBANKA_030470 serine repeat antigen 5 (SERA5) 1363 PBANKA_130920 serine/threonine kinase-1, putative 1364 PBANKA_101980 serine/threonine protein kinase, putative 1365 PBANKA_130520 serine/threonine protein kinase, putative 1366 PBANKA_146050 serine/threonine protein kinase, putative 1367 PBANKA_113310 serine/threonine protein kinase, putative (ARK3) 1368 PBANKA_050250 serine/threonine protein phosphatase, putative 1369 PBANKA_082850 serine/threonine protein phosphatase, putative 1370 PBANKA_132800 serine/threonine protein phosphatase, putative (UIS2) 1371 PBANKA_070290 SET domain protein, putative 1372 PBANKA_081120 SET domain protein, putative 1373 PBANKA_110770 SET domain protein, putative signal recognition particle receptor alpha subunit, 1374 PBANKA_114250 putative 1375 PBANKA_140300 small heat shock protein, putative 1376 PBANKA_092150 small nuclear ribonucleoprotein F, putative (SNRPF) small ribosomal subunit processing 1377 PBANKA_070930 microtubule-associated protein, putative 1378 PBANKA_144040 small subunit rRNA processing factor, putative 1379 PBANKA_120700 small subunit rRNA processing protein, putative 1380 PBANKA_051120 small subunit rRNA processing stabilizing factor, putative 1381 PBANKA_110860 SNAP protein, putative 1382 PBANKA_060850 SNARE protein, putative 1383 PBANKA_070400 SNARE protein, putative 1384 PBANKA_081170 SNARE protein, putative 1385 PBANKA_121840 SNARE protein, putative 1386 PBANKA_131230 SNARE protein, putative 1387 PBANKA_140170 SNARE protein, putative 1388 PBANKA_071080 Snf2-related CBP activator, putative (SRCAP) 1389 PBANKA_140200 sodium/hydrogen exchanger, Na , H antiporter, putative 1390 PBANKA_145310 sphingomyelin phosphodiesterase, putative 1391 PBANKA_130170 splicing factor 3A subunit 1, putative (SF3A1) 1392 PBANKA_082560 splicing factor 3A subunit 3, putative (SF3A3) 1393 PBANKA_092440 splicing factor, putative 1394 PBANKA_090210 sporozoite asparagine-rich protein (SLARP) sporozoite surface protein 2,thrombospondin-related 1395 PBANKA_134980 anonymous protein (TRAP) 1396 PBANKA_111070 stearoyl-CoA delta 9 desaturase, putative 1397 PBANKA_091170 subtilisin-like protease 2 (SUB2) 1398 PBANKA_110680 subtilisin-like protease 3, putative (SUB3) 1399 PBANKA_120870 succinate dehydrogenase subunit 4, putative (SDH4) 1400 PBANKA_081700 sugar transporter, putative 1401 PBANKA_144530 sun-family protein, putative 1402 PBANKA_102250 surface protein, putative 1403 PBANKA_093630 syntaxin, putative 1404 PBANKA_060440 targeted glyoxalase II, putative TATA-box binding protein, putative,transcription initiation 1405 PBANKA_110580 factor tfiid, putative (TBP) 1406 PBANKA_146180 tat-binding protein homolog, putative 1407 PBANKA_040520 T-complex protein beta subunit, putative 1408 PBANKA_091620 TCP-1/cpn60 chaperonin family, putative 1409 PBANKA_082570 telomeric repeat binding factor 1, putative 1410 PBANKA_112980 Tetratricopeptide repeat protein, putative 1411 PBANKA_141340 TFIIH basal transcription factor subunit, putative (UIS23) 1412 PBANKA_092220 ThiF family protein, putative 1413 PBANKA_082020 thioredoxin, putative 1414 PBANKA_134500 thioredoxin, putative 1415 PBANKA_135800 thioredoxin, putative (TRX2) threonyl-tRNA synthetase, putative,threonine--tRNA 1416 PBANKA_092230 ligase, putative (ThrRS) 1417 PBANKA_010920 trancription factor, putative 1418 PBANKA_135580 transcription activator, putative 1419 PBANKA_090590 transcription factor with AP2 domain(s) (AP2-O) transcription factor with AP2 domain(s), putative 1420 PBANKA_093230 (ApiAP2) transcription factor with AP2 domain(s), putative 1421 PBANKA_093910 (ApiAP2) transcription factor with AP2 domain(s), putative 1422 PBANKA_100180 (ApiAP2) transcription factor with AP2 domain(s), putative 1423 PBANKA_101550 (ApiAP2) transcription factor with AP2 domain(s), putative 1424 PBANKA_135600 (ApiAP2) 1425 PBANKA_100490 transcription factor, putative 1426 PBANKA_061500 transcription initiation factor IIE, alpha subunit, putative 1427 PBANKA_020290 transcription initiation factor TFIIB, putative 1428 PBANKA_092490 translation elongation factor EF-1, subunit alpha, putative 1429 PBANKA_134760 translation initiation factor 6, putative 1430 PBANKA_041280 translation initiation factor E4, putative (eIF4E) translation initiation factor IF-2, putative,sporozoite 1431 PBANKA_123140 surface antigen MB2, putative (MB2) translocation associated membrane protein, putative 1432 PBANKA_103830 (TRAM) 1433 PBANKA_094130 translocon component PTEX88, putative 1434 PBANKA_061100 transport protein particle (TRAPP) component, putative 1435 PBANKA_144540 transport protein Sec13, putative 1436 PBANKA_090350 transporter, putative 1437 PBANKA_091830 transporter, putative 1438 PBANKA_130380 triose-phosphate isomerase, putative (TIM) 1439 PBANKA_130620 tRNA binding protein, putative 1440 PBANKA_092900 tRNA m(1)G methyltransferase, putative 1441 PBANKA_050400 tRNA methyltransferase, putative 1442 PBANKA_051880 tRNA pseudouridine synthase D, putative 1443 PBANKA_123110 tRNA pseudouridine synthase, putative 1444 PBANKA_062050 tRNAHis guanylyltransferase, putative 1445 PBANKA_052430 tryptophan/threonine-rich antigen, putative 1446 PBANKA_062330 tryptophan-rich antigen, putative 1447 PBANKA_146470 tryptophanyl-tRNA synthetase, putative 1448 PBANKA_080840 tubulin-specific chaperone, putative 1449 PBANKA_071200 U3 small nucleolar ribonucleoprotein, putative U3 snoRNA-associated small subunit rRNA processing 1450 PBANKA_121150 protein, putative U3/U14 snoRNA-associated small subunit rRNA 1451 PBANKA_093780 processing protein, putative U4/U6 small nuclear ribonucleoprotein PRP3, putative 1452 PBANKA_140780 (PRPF3) U4/U6.U5 tri-snRNP-associated protein 2, putative 1453 PBANKA_141550 (USP39) U6 snRNA-associated Sm-like protein LSm1, putative 1454 PBANKA_092390 (LSM1) U6 snRNA-associated Sm-like protein LSm4, putative 1455 PBANKA_093990 (LSM4) ubiquinol-cytochrome c reductase complex subunit, 1456 PBANKA_121070 putative 1457 PBANKA_101770 ubiquinol-cytochrome c reductase hinge protein, putative 1458 PBANKA_134790 ubiquitin activating enzyme, putative 1459 PBANKA_123150 ubiquitin carboxyl-terminal hydrolase 2, putative ubiquitin carboxyl-terminal hydrolase isozyme L3, 1460 PBANKA_132410 putative (UCHL3) 1461 PBANKA_082190 ubiquitin conjugating enzyme, putative 1462 PBANKA_102970 ubiquitin conjugating enzyme, putative 1463 PBANKA_102470 ubiquitin fusion degradation protein UFD1, putative 1464 PBANKA_102090 ubiquitin ligase, putative 1465 PBANKA_122240 ubiquitin regulatory protein, putative 1466 PBANKA_091060 ubiquitin related modifier, putative 1467 PBANKA_041680 ubiquitin specific protease, putative 1468 PBANKA_144070 ubiquitin-activating enzyme e1, putative 1469 PBANKA_070410 ubiquitination-mediated degradation component, putative 1470 PBANKA_124190 ubiquitin-conjugating enzyme E2 N, putative (UBC13) 1471 PBANKA_010500 ubiquitin-conjugating enzyme e2, putative 1472 PBANKA_141330 ubiquitin-like protein, putative 1473 PBANKA_100110 ubiquitin-specific protease, putative 1474 PBANKA_052460 unspecified product 1475 PBANKA_101740 unspecified product (Sel4) 1476 PBANKA_010590 uroporphyrinogen III decarboxylase, putative (UROD) 1477 PBANKA_091130 UVB-resistance protein UVR8 homologue, putative 1478 PBANKA_090890 vacuolar ATP synthase subunit f, putative 1479 PBANKA_133840 vacuolar ATP synthase subunit g, putative 1480 PBANKA_140510 vacuolar ATP synthase subunit h, putative 1481 PBANKA_031310 vacuolar sorting protein VPS45, putative 1482 PBANKA_071460 vacuolar sorting protein, putative 1483 PBANKA_144490 vacuolar transporter chaperone, putative 1484 PBANKA_040920 valine -- tRNA ligase, putative 1485 PBANKA_145430 vesicle fusion and protein sorting subunit 16, putative 1486 PBANKA_083600 vesicle transport protein, putative 1487 PBANKA_122890 von willebrand factor a-domain-related protein (WARP) 1488 PBANKA_132050 V-type H( )-translocating pyrophosphatase, putative 1489 PBANKA_060050 XPA binding protein 1, putative 1490 PBANKA_081870 XPA binding protein 1, putative 1491 PBANKA_040790 YT521-B-like family protein, putative 1492 PBANKA_120680 zinc finger C-x8-C-x5-C-x3-H type, putative 1493 PBANKA_041240 zinc finger protein, putative 1494 PBANKA_041270 zinc finger protein, putative 1495 PBANKA_041360 zinc finger protein, putative 1496 PBANKA_071230 zinc finger protein, putative 1497 PBANKA_071270 zinc finger protein, putative 1498 PBANKA_113480 zinc finger protein, putative 1499 PBANKA_123270 zinc finger protein, putative 1500 PBANKA_140880 zinc finger protein, putative 1501 PBANKA_141970 zinc finger protein, putative 1502 PBANKA_143340 zinc finger protein, putative 1503 PBANKA_145800 zinc finger protein, putative 1504 PBANKA_060770 zinc finger transcription factor, putative 1505 PBANKA_050650 zinc transporter, putative aCommon peaks in two ChIP-seq experiments (3,584 peaks) were used for prediction of target genes. Genes were identified as AP2-G2 targets when their 1.2-kbp upstream regions contained the predicted summits of the AP2-G2 peaks. Only the summits in intergenic regions were used for target prediction. bGene ID and functional annotation were attributed to each gene according to those in PlasmoDB. Target genes were sorted in alphabetical order of attributed functional annotations.

Table S7. Classification of target genesa

Gene ID Functional annotation Protein biosynthesis 1 1 PBANKA_061720 40S ribosomal protein S10, putative 2 2 PBANKA_040540 40S ribosomal protein S12, putative 3 3 PBANKA_123100 40S ribosomal protein S14, putative 4 4 PBANKA_141630 40S ribosomal protein S15/S19, putative 5 5 PBANKA_041460 40S ribosomal protein S15A, putative 6 6 PBANKA_145610 40S ribosomal protein S17, putative 7 7 PBANKA_120190 40S ribosomal protein S20e, putative 8 8 PBANKA_090500 40S ribosomal protein S21e, putative 9 9 PBANKA_123420 40S ribosomal protein S24, putative 10 10 PBANKA_102200 40S ribosomal protein S25, putative 11 11 PBANKA_080340 40S ribosomal protein S29, putative 12 12 PBANKA_031560 40S ribosomal protein S30, putative 13 13 PBANKA_103940 40S ribosomal protein S31/UBI, putative 14 14 PBANKA_121560 40S ribosomal protein S3A, putative 15 15 PBANKA_061910 40S ribosomal protein S5, putative 16 16 PBANKA_135510 40S ribosomal protein S6, putative 17 17 PBANKA_140130 40S ribosomal protein S7, putative 18 18 PBANKA_040770 60S acidic ribosomal protein P2, putative 19 19 PBANKA_094360 60S acidic ribosomal protein, putative 20 20 PBANKA_102840 60S ribosomal protein L10, putative 21 21 PBANKA_061710 60S ribosomal protein L11a, putative 22 22 PBANKA_123180 60S ribosomal protein L12, putative 23 23 PBANKA_101310 60S ribosomal protein L14, putative 24 24 PBANKA_136420 60S ribosomal protein L17, putative 25 25 PBANKA_122920 60S ribosomal protein L19, putative 26 26 PBANKA_070910 60S ribosomal protein L22, putative 27 27 PBANKA_134670 60S ribosomal protein L23, putative 28 28 PBANKA_133860 60S ribosomal protein L23a, putative 29 29 PBANKA_041060 60S ribosomal protein L26, putative 30 30 PBANKA_090650 60S ribosomal protein L28, putative 31 31 PBANKA_051190 60S ribosomal protein L3, putative 32 32 PBANKA_050360 60S ribosomal protein L30e, putative 33 33 PBANKA_122120 60S ribosomal protein L34a, putative 34 34 PBANKA_092340 60S ribosomal protein L35, putative 35 35 PBANKA_090640 60S ribosomal protein L35ae, putative 36 36 PBANKA_030700 60S ribosomal protein L37ae, putative 37 37 PBANKA_091810 60S ribosomal protein L38e, putative 38 38 PBANKA_114170 60S ribosomal protein L40/UBI, putative 39 39 PBANKA_090470 60S ribosomal protein L41, putative 40 40 PBANKA_133830 60S ribosomal protein L6, putative 41 41 PBANKA_135190 60S ribosomal protein L6-2, putative 42 42 PBANKA_040550 60S ribosomal protein L7, putative 43 43 PBANKA_113120 60S ribosomal protein L7-2, putative 44 44 PBANKA_123170 60S ribosomal protein L8, putative 45 45 PBANKA_091800 60S ribosomal protein, putative 46 46 PBANKA_021340 60S ribosomal subunit export protein, putative 47 47 PBANKA_110570 60S ribosomal subunit protein L24, putative 48 48 PBANKA_021020 aspartyl-tRNA synthetase, putative 49 49 PBANKA_142960 bi-functional aminoacyl-tRNA synthetase, putative 50 50 PBANKA_103640 BOP1-like protein, putative 51 51 PBANKA_071170 BRIX domain, putative 52 52 PBANKA_021350 BRIX protein, putative 53 53 PBANKA_122640 cactin homolog, putative 54 54 PBANKA_145280 cell cycle control protein, putative 55 55 PBANKA_070920 clp1-related protein, putative 56 56 PBANKA_101350 cytosolic preribosomal GTPase, putative 57 57 PBANKA_130300 DEAD/DEAH helicase, putative 58 58 PBANKA_140110 deoxyhypusine hydroxylase, putative 59 59 PBANKA_103000 deoxyhypusine synthase, putative 60 60 PBANKA_133180 derlin-2, putative 61 61 PBANKA_121890 elongation factor 1 (EF-1), putative 62 62 PBANKA_113330 elongation factor 1 alpha (EF-1alpha) 63 63 PBANKA_113340 elongation factor 1 alpha (EF-1alpha) 64 64 PBANKA_081420 elongation factor 1-beta, putative 65 65 PBANKA_135200 elongation factor 1-gamma, putative 66 66 PBANKA_131480 elongation factor 2, putative 67 67 PBANKA_061080 eukaryotic initiation factor 2a, putative eukaryotic translation initation factor 4 gamma, putative 68 68 PBANKA_141130 (EIF4G) eukaryotic translation initiation factor 2 alpha subunit, 69 69 PBANKA_021210 putative 70 70 PBANKA_146350 eukaryotic translation initiation factor 2b, putative 71 71 PBANKA_142870 eukaryotic translation initiation factor 3 subunit 10, putative 72 72 PBANKA_081930 eukaryotic translation initiation factor 3 subunit 5, putative 73 73 PBANKA_120610 eukaryotic translation initiation factor 3 subunit 7, putative 74 74 PBANKA_060320 eukaryotic translation initiation factor 5a, putative (EIF5A) 75 75 PBANKA_061450 eukaryotic translation initiation factor subunit, putative 76 76 PBANKA_103510 fibrillarin, putative (NOP1) 77 77 PBANKA_136200 glutamate - tRNA ligase, putative 78 78 PBANKA_134660 glutaminyl-tRNA synthetase, putative 79 79 PBANKA_130890 histidine -- tRNA ligase, putative 80 80 PBANKA_121230 initiation factor 2 subunit family, putative 81 81 PBANKA_061380 large ribosomal subunit assembling factor, putative 82 82 PBANKA_133010 large ribosomal subunit assembling protein, putative large ribosomal subunit nuclear export factor, putative 83 83 PBANKA_132140 (UIS20) 84 84 PBANKA_050420 large subunit rRNA processing RRM protein, putative 85 85 PBANKA_101020 methionine aminopeptidase, type II, putative 86 86 PBANKA_051870 methionine-tRNA ligase, putative 87 87 PBANKA_082600 methyltransferase, putative 88 88 PBANKA_092110 methyltransferase, putative 89 89 PBANKA_113090 methyltransferase, putative 90 90 PBANKA_021360 mRNA (N6-adenosine)-methyltransferase, putative 91 91 PBANKA_083380 mRNA processing protein, putative nascent polypeptide associated complex alpha chain, 92 92 PBANKA_112070 putative 93 93 PBANKA_092350 nuclear preribosomal assembly protein, putative 94 94 PBANKA_011120 nucleolar GTP-binding protein 1, putative 95 95 PBANKA_124110 nucleolar Jumonji domain interacting protein, putative 96 96 PBANKA_051240 nucleolar preribosomal assembly protein, putative 97 97 PBANKA_051250 nucleolar preribosomal assembly protein, putative 98 98 PBANKA_071240 nucleolar preribosomal assembly protein, putative 99 99 PBANKA_071480 nucleolar preribosomal assembly protein, putative 100 100 PBANKA_090310 nucleolar preribosomal assembly protein, putative nucleolar preribosomal associated cytoplasmic ATPase, 101 101 PBANKA_136260 putative 102 102 PBANKA_124340 nucleolar preribosomal GTPase, putative 103 103 PBANKA_083190 nucleolar protein Nop52, putative 104 104 PBANKA_100480 peptidyl-tRNA hydrolase, putative 105 105 PBANKA_094290 phenylalanyl-tRNA synthetase beta chain, putative 106 106 PBANKA_010520 polypyrimidine tract binding protein, putative 107 107 PBANKA_011090 PP-loop family protein, putative 108 108 PBANKA_040910 pre-mRNA splicing factor, putative 109 109 PBANKA_082360 pre-mRNA splicing factor, putative 110 110 PBANKA_103930 pre-mRNA splicing factor, putative 111 111 PBANKA_143530 pre-mRNA splicing factor, putative 112 112 PBANKA_040680 pre-mRNA-processing factor 19, putative (PRPF19) pre-mRNA-splicing factor ATP-dependent RNA helicase 113 113 PBANKA_144630 PRP2, putative (PRP2) pre-mRNA-splicing factor ATP-dependent RNA helicase 114 114 PBANKA_081860 PRP43, putative (PRP43) 115 115 PBANKA_010860 Pre-mRNA-splicing factor SLU7, putative (SLU7) 116 116 PBANKA_052290 pre-mRNA-splicing helicase BRR2, putative (BRR2) 117 117 PBANKA_101630 proliferation-associated protein 2g4, putative 118 118 PBANKA_092660 protein GCN20, putative 119 119 PBANKA_061510 queuine tRNA-ribosyltransferase, putative 120 120 PBANKA_121610 regulator of initiation factor 2, putative 121 121 PBANKA_134290 regulator of nonsense transcripts 3B, putative (UPF3B) 122 122 PBANKA_134240 ribonuclease P protein subunit rpr, putative 123 123 PBANKA_122010 ribonucleases p/mrp protein subunit, putative 124 124 PBANKA_111750 ribosomal protein L27a, putative 125 125 PBANKA_132400 ribosomal protein L29, putative 126 126 PBANKA_080400 ribosomal protein, L37e, putative 127 127 PBANKA_031580 ribosome associated membrane protein RAMP4, putative 128 128 PBANKA_114350 ribosome biogenesis protein MRT4, putative 129 129 PBANKA_052180 ribosome recycling factor, putative 130 130 PBANKA_030570 ribosome-recycling factor, putative (RRF) 131 131 PBANKA_091880 RNA methyltransferase, putative 132 132 PBANKA_111100 RNA pseudouridylate synthase, putative, fragment 133 133 PBANKA_101530 rRNA (adenosine-2'-O-)-methyltransferase, putative 134 134 PBANKA_040780 SECIS-binding protein 2, putative (SBP2) 135 135 PBANKA_092150 small nuclear ribonucleoprotein F, putative (SNRPF) small ribosomal subunit processing 136 136 PBANKA_070930 microtubule-associated protein, putative 137 137 PBANKA_144040 small subunit rRNA processing factor, putative 138 138 PBANKA_120700 small subunit rRNA processing protein, putative 139 139 PBANKA_051120 small subunit rRNA processing stabilizing factor, putative 140 140 PBANKA_130170 splicing factor 3A subunit 1, putative (SF3A1) 141 141 PBANKA_082560 splicing factor 3A subunit 3, putative (SF3A3) 142 142 PBANKA_092440 splicing factor, putative 143 143 PBANKA_092490 translation elongation factor EF-1, subunit alpha, putative 144 144 PBANKA_134760 translation initiation factor 6, putative 145 145 PBANKA_041280 translation initiation factor E4, putative (eIF4E) translation initiation factor IF-2, putative,sporozoite surface 146 146 PBANKA_123140 antigen MB2, putative (MB2) 147 147 PBANKA_130620 tRNA binding protein, putative 148 148 PBANKA_092900 tRNA m(1)G methyltransferase, putative 149 149 PBANKA_050400 tRNA methyltransferase, putative 150 150 PBANKA_051880 tRNA pseudouridine synthase D, putative 151 151 PBANKA_123110 tRNA pseudouridine synthase, putative 152 152 PBANKA_062050 tRNAHis guanylyltransferase, putative 153 153 PBANKA_071200 U3 small nucleolar ribonucleoprotein, putative U3 snoRNA-associated small subunit rRNA processing 154 154 PBANKA_121150 protein, putative U3/U14 snoRNA-associated small subunit rRNA 155 155 PBANKA_093780 processing protein, putative U4/U6 small nuclear ribonucleoprotein PRP3, putative 156 156 PBANKA_140780 (PRPF3) U4/U6.U5 tri-snRNP-associated protein 2, putative 157 157 PBANKA_141550 (USP39) 158 158 PBANKA_040920 valine -- tRNA ligase, putative Organella 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 159 1 PBANKA_133060 putative 160 2 PBANKA_082380 3-oxoacyl-(acyl-carrier protein) reductase, putative 3-oxoacyl-acyl-carrier protein synthase, putative 161 3 PBANKA_112510 (FabB/FabF) 162 4 PBANKA_030170 5'-3' exonuclease, putative 163 5 PBANKA_144680 60 kDa chaperonin, putative (CPN60) 164 6 PBANKA_091870 A/G-specific adenine glycosylase, putative 165 7 PBANKA_136480 ABC transporter, putative 166 8 PBANKA_142730 ABC1 family, putative 167 9 PBANKA_135520 aconitase, putative 168 10 PBANKA_030560 acyl carrier protein, putative (ACP) 169 11 PBANKA_071760 adenylate kinase 1, putative alanine--tRNA ligase, putative,alanyl-tRNA synthetase, 170 12 PBANKA_114360 putative (AlaRS) 171 13 PBANKA_114050 aldo-keto reductase, putative 172 14 PBANKA_141670 apicoplast glycerol-3-phosphate acyltransferase, putative 173 15 PBANKA_090430 apicoplast import protein Tic20, putative (TIC20) 174 16 PBANKA_011170 apicoplast ribosomal protein L18 precursor, putative 175 17 PBANKA_142740 apicoplast ribosomal protein L33 precursor, putative 176 18 PBANKA_093770 apicoplast ribosomal protein L36e precursor, putative 177 19 PBANKA_094080 apicoplast ribosomal protein S15 precursor, putative 178 20 PBANKA_135770 aspartate carbamoyltransferase, putative 179 21 PBANKA_061200 ATP-dependent Clp protease proteolytic subunit, putative 180 22 PBANKA_103560 ATP-dependent Clp protease, putative 181 23 PBANKA_050410 autophagy-related protein 8, putative (ATG8) 182 24 PBANKA_010200 bcs1-like protein, putative 183 25 PBANKA_133820 beta-hydroxyacyl-ACP dehydratase, putative (FabZ) 184 26 PBANKA_021190 cation transporting ATPase, putative 185 27 PBANKA_010230 cation/H antiporter, putative (CHA) 186 28 PBANKA_040130 CDGSH iron-sulfur domain-containing protein, putative 187 29 PBANKA_121940 Cg3 protein, putative 188 30 PBANKA_050670 citrate synthase, mitochondrial precursor, putative 189 31 PBANKA_071420 ClpB protein, putative 190 32 PBANKA_081910 cytochrome b5, putative 191 33 PBANKA_143950 cytochrome c heme lyase, putative 192 34 PBANKA_060080 cytochrome c oxidase assembly protein, putative 193 35 PBANKA_130090 cytochrome c oxidase assembly protein, putative 194 36 PBANKA_082860 cytochrome c oxidase subunit, putative 195 37 PBANKA_082880 cytochrome c oxidase, putative 196 38 PBANKA_060260 cytochrome c1 heme lyase, putative 197 39 PBANKA_141020 cytochrome c2 precursor,putative 198 40 PBANKA_130410 delta-aminolevulinic acid dehydratase, putative 199 41 PBANKA_130760 dephospho-CoA kinase, putative 200 42 PBANKA_041200 DER1-like protein, putative 201 43 PBANKA_070670 dicarboxylate/tricarboxylate carrier, putative (DTC) 202 44 PBANKA_050500 dihydrolipoamide acyltransferase, putative 203 45 PBANKA_144690 dihydrolipoamide dehydrogenase, putative (mLipDH) 204 46 PBANKA_010210 dihydroorotate dehydrogenase, putative 205 47 PBANKA_081970 dihydrouridine synthase, putative 206 48 PBANKA_102690 dimethyladenosine transferase, putative 207 49 PBANKA_112780 DnaJ protein, putative 208 50 PBANKA_144770 elongation factor G, putative (EF-G) 209 51 PBANKA_122980 enoyl-acyl carrier reductase (FABI) FAD-dependent glycerol-3-phosphate dehydrogenase, 210 52 PBANKA_040480 putative 211 53 PBANKA_141660 ferredoxin, putative 212 54 PBANKA_112210 ferredoxin--NADP reductase, putative 213 55 PBANKA_145730 glucose inhibited division protein a homologue, putative 214 56 PBANKA_113350 glutamate - tRNA ligase, putative 215 57 PBANKA_071810 glutamyl-tRNA(Gln) amidotransferase subunit A, putative 216 58 PBANKA_093290 glycerol-3-phosphate dehydrogenase, putative 217 59 PBANKA_091550 glycine cleavage system H protein, putative 218 60 PBANKA_121400 heat shock protein 60, putative 219 61 PBANKA_052160 holo-(acyl-carrier protein) synthase, putative 220 62 PBANKA_030460 iron-sulfur assembly protein, putative isocitrate dehydrogenase (NADP), mitochondrial 221 63 PBANKA_135860 precursor, putative (IDH) 222 64 PBANKA_011050 leucine-rich repeat protein (LRR6) 223 65 PBANKA_031180 long-chain acyl-CoA synthase, putative malonyl CoA-acyl carrier protein transacylase precursor, 224 66 PBANKA_141050 putative 225 67 PBANKA_120330 methionine-tRNA ligase, putative 226 68 PBANKA_020510 mitochondrial carrier protein, putative 227 69 PBANKA_145500 mitochondrial carrier protein, putative 228 70 PBANKA_113250 mitochondrial inner membrane translocase, putative 229 71 PBANKA_060110 mitochondrial phosphate carrier protein, putative 230 72 PBANKA_102180 mitochondrial protein import protein TIM13, putative 231 73 PBANKA_122150 mitochondrial ribosomal protein L1 precursor, putative 232 74 PBANKA_030900 mitochondrial ribosomal protein L12 precursor, putative 233 75 PBANKA_041390 mitochondrial ribosomal protein L27 precursor, putative 234 76 PBANKA_145860 mitochondrial ribosomal protein L3 precursor, putative 235 77 PBANKA_135290 mitochondrial ribosomal protein L49 precursor, putative 236 78 PBANKA_131110 mitochondrial ribosomal protein S14 precursor, putative 237 79 PBANKA_061000 mitochondrial ribosomal protein S18 precursor, putative 238 80 PBANKA_051130 mitochondrial ribosomal protein S22 precursor, putative 239 81 PBANKA_091160 mitochondrial ribosomal protein S9 precursor, putative 240 82 PBANKA_136350 N6-adenine-specific methylase, putative 241 83 PBANKA_102620 NADP-specific glutamate dehydrogenase, putative (GDH1) 242 84 PBANKA_101400 NADP-specific glutamate dehydrogenase, putative (GDH2) 243 85 PBANKA_103340 oxidoreductase, putative 244 86 PBANKA_144670 phenylalanyl-tRNA synthetase alpha chain, putative 245 87 PBANKA_081520 phospholipid or glycerol acyltransferase, putative 246 88 PBANKA_133870 plasmepsin V, putative (PMV) 247 89 PBANKA_060800 porphobilinogen deaminase, putative 248 90 PBANKA_121310 prohibitin, putative 249 91 PBANKA_131010 pyruvate dehydrogenase E1 beta subunit, putative pyruvate dehydrogenase E1 component, alpha subunit, 250 92 PBANKA_092380 putative 251 93 PBANKA_052000 pyruvate kinase 2, putative 252 94 PBANKA_102700 serine C-palmitoyltransferase, putative 253 95 PBANKA_120870 succinate dehydrogenase subunit 4, putative (SDH4) 254 96 PBANKA_060440 targeted glyoxalase II, putative 255 97 PBANKA_135800 thioredoxin, putative (TRX2) threonyl-tRNA synthetase, putative,threonine--tRNA ligase, 256 98 PBANKA_092230 putative (ThrRS) 257 99 PBANKA_090350 transporter, putative 258 100 PBANKA_146470 tryptophanyl-tRNA synthetase, putative ubiquinol-cytochrome c reductase complex subunit, 259 101 PBANKA_121070 putative 260 102 PBANKA_101770 ubiquinol-cytochrome c reductase hinge protein, putative 261 103 PBANKA_010590 uroporphyrinogen III decarboxylase, putative (UROD) 262 104 PBANKA_090890 vacuolar ATP synthase subunit f, putative Protein vesicular transport 263 1 PBANKA_021430 adapter-related protein, putative 264 2 PBANKA_130460 adaptor complexes medium subunit family adaptor-related protein complex 3, sigma 2 subunit, 265 3 PBANKA_146340 putative 266 4 PBANKA_072060 Bet3 transport protein, putative 267 5 PBANKA_145890 clathrin coat assembly protein AP180, putative 268 6 PBANKA_031400 clathrin coat assembly protein, putative 269 7 PBANKA_140990 clathrin-adaptor medium chain, putative 270 8 PBANKA_010540 coatomer alpha subunit, putative 271 9 PBANKA_141730 DnaJ/SEC63 protein, putative 272 10 PBANKA_040280 EH (Eps15 homology) protein, putative endoplasmic reticulum-resident calcium binding protein, 273 11 PBANKA_093840 putative 274 12 PBANKA_143730 endoplasmin homolog precursor, putative 275 13 PBANKA_145680 endosome sorting protein (SNF7 homologue), putative 276 14 PBANKA_093160 ER membrane protein Sec12, putative (SEC12) 277 15 PBANKA_131930 ferlin, putative 278 16 PBANKA_050160 golgi re-assembly stacking protein, putative (GRASP) 279 17 PBANKA_093340 GTPase activating protein, putative 280 18 PBANKA_122570 GTPase activating protein, putative 281 19 PBANKA_111310 GTP-binding protein, putative 282 20 PBANKA_070800 protein transport protein Sec23, putative (SEC23) 283 21 PBANKA_134680 Qa-SNARE protein, putative 284 22 PBANKA_135410 Rab GTPase 11b 285 23 PBANKA_145620 rab specific GDP dissociation inhibitor, putative (rabGDI) 286 24 PBANKA_111350 Rab1a, putative 287 25 PBANKA_140910 Rab5b, GTPase, putative 288 26 PBANKA_090410 Rab6 289 27 PBANKA_111620 ras GTPAse, putative 290 28 PBANKA_112520 Sec14 protein, putative 291 29 PBANKA_100280 Sec24-like protein, putative 292 30 PBANKA_135900 sec61 alpha subunit, putative 293 31 PBANKA_114250 signal recognition particle receptor alpha subunit, putative 294 32 PBANKA_110860 SNAP protein, putative 295 33 PBANKA_060850 SNARE protein, putative 296 34 PBANKA_070400 SNARE protein, putative 297 35 PBANKA_081170 SNARE protein, putative 298 36 PBANKA_121840 SNARE protein, putative 299 37 PBANKA_131230 SNARE protein, putative 300 38 PBANKA_140170 SNARE protein, putative 301 39 PBANKA_093630 syntaxin, putative translocation associated membrane protein, putative 302 40 PBANKA_103830 (TRAM) 303 41 PBANKA_094130 translocon component PTEX88, putative 304 42 PBANKA_061100 transport protein particle (TRAPP) component, putative 305 43 PBANKA_144540 transport protein Sec13, putative 306 44 PBANKA_031310 vacuolar sorting protein VPS45, putative 307 45 PBANKA_071460 vacuolar sorting protein, putative 308 46 PBANKA_144490 vacuolar transporter chaperone, putative 309 47 PBANKA_145430 vesicle fusion and protein sorting subunit 16, putative 310 48 PBANKA_083600 vesicle transport protein, putative Exported protein 311 1 PBANKA_010050 BIR protein 312 2 PBANKA_020125 BIR protein, pseudogene 313 3 PBANKA_083655 BIR protein, pseudogene 314 4 PBANKA_020145 BIR protein, pseudogene, fragment 315 5 PBANKA_020160 early transcribed membrane protein (ETRAMP) 316 6 PBANKA_051700 early transcribed membrane protein (ETRAMP) 317 7 PBANKA_133430 exported protein 2, putative (EXP2) 318 8 PBANKA_020920 parasite-infected erythrocyte surface protein (PIESP15) 319 9 PBANKA_020020 Pb-fam-1 protein 320 10 PBANKA_020060 Pb-fam-1 protein 321 11 PBANKA_021490 Pb-fam-1 protein 322 12 PBANKA_060040 Pb-fam-1 protein 323 13 PBANKA_062340 Pb-fam-1 protein 324 14 PBANKA_062350 Pb-fam-1 protein 325 15 PBANKA_090100 Pb-fam-1 protein 326 16 PBANKA_110090 Pb-fam-1 protein 327 17 PBANKA_110100 Pb-fam-1 protein 328 18 PBANKA_124610 Pb-fam-1 protein 329 19 PBANKA_136560 Pb-fam-1 protein 330 20 PBANKA_020120 Pb-fam-1 protein, pseudogene 331 21 PBANKA_021555 Pb-fam-1 protein, pseudogene 332 22 PBANKA_040080 Pb-fam-1 protein, pseudogene 333 23 PBANKA_062345 Pb-fam-1 protein, pseudogene 334 24 PBANKA_010020 Plasmodium exported protein, unknown function 335 25 PBANKA_020080 Plasmodium exported protein, unknown function 336 26 PBANKA_020150 Plasmodium exported protein, unknown function 337 27 PBANKA_021470 Plasmodium exported protein, unknown function 338 28 PBANKA_021560 Plasmodium exported protein, unknown function 339 29 PBANKA_031630 Plasmodium exported protein, unknown function 340 30 PBANKA_070060 Plasmodium exported protein, unknown function 341 31 PBANKA_070070 Plasmodium exported protein, unknown function 342 32 PBANKA_083640 Plasmodium exported protein, unknown function 343 33 PBANKA_110120 Plasmodium exported protein, unknown function 344 34 PBANKA_114540 Plasmodium exported protein, unknown function 345 35 PBANKA_114620 Plasmodium exported protein, unknown function 346 36 PBANKA_120060 Plasmodium exported protein, unknown function 347 37 PBANKA_120710 Plasmodium exported protein, unknown function 348 38 PBANKA_122900 Plasmodium exported protein, unknown function 349 39 PBANKA_124590 Plasmodium exported protein, unknown function 350 40 PBANKA_124592 Plasmodium exported protein, unknown function 351 41 PBANKA_146500 Plasmodium exported protein, unknown function 352 42 PBANKA_021460 Plasmodium exported protein, unknown function, fragment 353 43 PBANKA_021455 Plasmodium exported protein, unknown function, pseudogene Merozoite formation 354 1 PBANKA_145930 actin I 355 2 PBANKA_110310 actin-depolymerizing factor 1 (ADF1) 356 3 PBANKA_100290 ag-1 blood stage membrane protein homologue 357 4 PBANKA_091500 apical membrane antigen 1 (AMA1) 358 5 PBANKA_072180 apical merozoite protein, putative 359 6 PBANKA_135150 calcium dependent protein kinase 5 (CDPK5) 360 7 PBANKA_140060 cytoadherence linked asexual protein, putative 361 8 PBANKA_133270 duffy-binding protein glideosome associated protein with multiple membrane 362 9 PBANKA_133890 spans 1, putative (GAPM1) glideosome associated protein with multiple membrane 363 10 PBANKA_052390 spans 2, putative (GAPM2) 364 11 PBANKA_143760 glideosome-associated protein 45, putative 365 12 PBANKA_120200 membrane skeletal protein, putative 366 13 PBANKA_083100 merozoite surface protein 1 (MSP1) 367 14 PBANKA_111960 merozoite surface protein 10, putative (MSP10) 368 15 PBANKA_134910 merozoite surface protein 7 (MSP7) 369 16 PBANKA_134920 MSP7-like protein (MSRP1) 370 17 PBANKA_134900 MSP7-like protein (MSRP2) 371 18 PBANKA_135570 myosin A (MyoA) 372 19 PBANKA_020460 photosensitized INA-labeled protein 1, putative 373 20 PBANKA_083300 profilin, putative (PFN) 374 21 PBANKA_070090 reticulocyte-binding protein, putative 375 22 PBANKA_121510 Rh5 interacting protein, putative (RIPR) 376 23 PBANKA_060500 rhodanese like protein, putative 377 24 PBANKA_070270 rhomboid protease, putative 378 25 PBANKA_111470 rhomboid protease, putative 379 26 PBANKA_041600 RhopH3, putative 380 27 PBANKA_146490 rhoptry neck protein 3, putative (RON3) 381 28 PBANKA_071310 rhoptry neck protein 5, putative (RON5) 382 29 PBANKA_031170 rhoptry neck protein 6, putative (RON6) 383 30 PBANKA_010040 rhoptry protein, putative 384 31 PBANKA_114230 rhoptry protein, putative 385 32 PBANKA_133030 rhoptry protein, putative 386 33 PBANKA_103210 rhoptry-associated protein 1, putative (RAP1) 387 34 PBANKA_110140 rhoptry-associated protein 2/3 (RAP2/3) schizont membrane associated cytoadherence protein 388 35 PBANKA_010060 (SMAC) 389 36 PBANKA_030510 serine repeat antigen 1 (SERA1) 390 37 PBANKA_030500 serine repeat antigen 2 (SERA2) 391 38 PBANKA_030490 serine repeat antigen 3 (SERA3) 392 39 PBANKA_080840 tubulin-specific chaperone, putative Protein kinase/ protein phosphatase 393 1 PBANKA_031420 calcium dependent protein kinase 1 (CDPK1) 394 2 PBANKA_142160 calcium/calmodulin-dependent protein kinase, putative CAMP-dependent protein kinase regulatory subunit, 395 3 PBANKA_143800 putative (PKAr) 396 4 PBANKA_093860 casein kinase 2, alpha subunit (CK2alpha) 397 5 PBANKA_071990 cdc2-related protein kinase 1 (CRK1) 398 6 PBANKA_123320 cyclin, putative 399 7 PBANKA_140320 cyclin, putative 400 8 PBANKA_122690 mitogen-activated protein kinase organizer 1, putative 401 9 PBANKA_071330 protein kinase c inhibitor-like protein, putative 402 10 PBANKA_090110 protein kinase, putative 403 11 PBANKA_094010 protein kinase, putative 404 12 PBANKA_101620 protein kinase, putative 405 13 PBANKA_110320 protein kinase, putative 406 14 PBANKA_122880 protein kinase, putative 407 15 PBANKA_141450 protein kinase, putative 408 16 PBANKA_144560 protein kinase, putative 409 17 PBANKA_092700 protein kinase, putative (TKL2) 410 18 PBANKA_070390 receptor for activated C kinase, putative (RACK) 411 19 PBANKA_130920 serine/threonine kinase-1, putative 412 20 PBANKA_101980 serine/threonine protein kinase, putative 413 21 PBANKA_130520 serine/threonine protein kinase, putative 414 22 PBANKA_146050 serine/threonine protein kinase, putative 415 23 PBANKA_113310 serine/threonine protein kinase, putative (ARK3) 416 24 PBANKA_091340 protein phosphatase 2C, putative 417 25 PBANKA_051550 protein phosphatase inhibitor, putative 418 26 PBANKA_132950 protein serine/threonine phosphatase, putative 419 27 PBANKA_093430 protein tyrosine phosphatase, putative 420 28 PBANKA_050250 serine/threonine protein phosphatase, putative 421 29 PBANKA_082850 serine/threonine protein phosphatase, putative 422 30 PBANKA_132800 serine/threonine protein phosphatase, putative (UIS2) Transcriptional regulation 423 1 PBANKA_090260 CCAAT-box DNA binding protein subunit B, putative 424 2 PBANKA_051910 CCAT-binding transcription factor-like protein, putative 425 3 PBANKA_051920 CCAT-binding transcription factor-like protein, putative CCR4-NOT transcription complex subunit 1, putative 426 4 PBANKA_094310 (NOT1) CCR4-NOT transcription complex subunit 4, putative 427 5 PBANKA_144990 (NOT4) 428 6 PBANKA_092300 DNA-dependent RNA polymerase, putative 429 7 PBANKA_134400 DNA-directed RNA polymerase 3 largest subunit, putative 430 8 PBANKA_030320 DNA-directed RNA polymerase II 16 kDa subunit, putative 431 9 PBANKA_082390 DNA-directed RNA polymerase II, putative 432 10 PBANKA_040190 DNA-directed RNA polymerase subunit I, putative 433 11 PBANKA_133590 DNA-directed RNA polymerase, alpha subunit, putative 434 12 PBANKA_141430 Myb1 protein, putative 435 13 PBANKA_110900 RNA polymerase I, putative 436 14 PBANKA_102750 RNA polymerase small subunit, putative 437 15 PBANKA_094220 RNA polymerase subunit, putative 438 16 PBANKA_102190 RNA polymerase subunit, putative TATA-box binding protein, putative,transcription initiation 439 17 PBANKA_110580 factor tfiid, putative (TBP) 440 18 PBANKA_146180 tat-binding protein homolog, putative 441 19 PBANKA_141340 TFIIH basal transcription factor subunit, putative (UIS23) 442 20 PBANKA_010920 trancription factor, putative 443 21 PBANKA_135580 transcription activator, putative 444 22 PBANKA_093230 transcription factor with AP2 domain(s), putative (ApiAP2) 445 23 PBANKA_093910 transcription factor with AP2 domain(s), putative (ApiAP2) 446 24 PBANKA_100180 transcription factor with AP2 domain(s), putative (ApiAP2) 447 25 PBANKA_101550 transcription factor with AP2 domain(s), putative (ApiAP2) 448 26 PBANKA_135600 transcription factor with AP2 domain(s), putative (ApiAP2) 449 27 PBANKA_100490 transcription factor, putative 450 28 PBANKA_061500 transcription initiation factor IIE, alpha subunit, putative 451 29 PBANKA_020290 transcription initiation factor TFIIB, putative 452 30 PBANKA_060770 zinc finger transcription factor, putative RNA binding 453 1 PBANKA_140120 ATP-dependent DEAD box helicase, putative 454 2 PBANKA_132270 ATP-dependent RNA helicase DBP5, putative 455 3 PBANKA_070950 ATP-dependent RNA helicase prh1, putative 456 4 PBANKA_100270 ATP-dependent RNA helicase, putative 457 5 PBANKA_102410 ATP-dependent RNA helicase, putative 458 6 PBANKA_124400 cell cycle regulator protein, putative 459 7 PBANKA_110720 cell differentiation protein, putative (CAF40) 460 8 PBANKA_061880 DEAD box helicase, putative 461 9 PBANKA_112970 DEAD/DEAH box ATP-dependent RNA helicase, putative 462 10 PBANKA_123630 DEAD-box subfamily ATP-dependent helicase, putative 463 11 PBANKA_135920 DNA/RNA-binding protein Alba 2, putative (ALBA2) 464 12 PBANKA_120440 DNA/RNA-binding protein Alba 3, putative (ALBA3) 465 13 PBANKA_100780 exosome complex component RRP4, putative (RRP4) 466 14 PBANKA_081110 helicase, putative 467 15 PBANKA_102550 NOT family protein, putative 468 16 PBANKA_051380 RAP protein, putative 469 17 PBANKA_080330 RNA helicase, putative 470 18 PBANKA_102430 RNA helicase, putative 471 19 PBANKA_122350 RNA helicase, putative 472 20 PBANKA_130900 RNA helicase, putative 473 21 PBANKA_070740 RNA-binding protein, putative 474 22 PBANKA_071790 RNA-binding protein, putative 475 23 PBANKA_082480 RNA-binding protein, putative 476 24 PBANKA_083000 RNA-binding protein, putative 477 25 PBANKA_103630 RNA-binding protein, putative U6 snRNA-associated Sm-like protein LSm1, putative 478 26 PBANKA_092390 (LSM1) U6 snRNA-associated Sm-like protein LSm4, putative 479 27 PBANKA_093990 (LSM4) 480 28 PBANKA_040790 YT521-B-like family protein, putative DNA replication/mitosis 481 1 PBANKA_134740 apurinic/apyrimidinic endonuclease, putative 482 2 PBANKA_094140 caltractin (centrin), putative (CEN4) 483 3 PBANKA_051180 centrin-3, putative 484 4 PBANKA_020740 DNA binding protein, putative 485 5 PBANKA_081950 DNA helicase, putative 486 6 PBANKA_112420 DNA polymerase 1, putative 487 7 PBANKA_061320 DNA polymerase alpha, putative 488 8 PBANKA_050130 DNA polymerase delta catalytic subunit, putative 489 9 PBANKA_020560 DNA repair exonuclease, putative 490 10 PBANKA_071830 DNA replication licensing factor, putative 491 11 PBANKA_094020 dna2/nam7 helicase family member, putative 492 12 PBANKA_120860 DNA2/NAM7 helicase, putative 493 13 PBANKA_133040 DNA-3-methyladenine glycosylase, putative 494 14 PBANKA_101910 DNA-directed DNA polymerase, putative 495 15 PBANKA_122950 endonuclease III homologue, putative 496 16 PBANKA_062250 exonuclease I, putative 497 17 PBANKA_081580 GINS complex subunit Psf3, putative 498 18 PBANKA_111380 helicase, putative (UIS26) minchromosome maintenance (MCM) complex subunit, 499 19 PBANKA_061020 putative (MCM5) 500 20 PBANKA_111570 Ndc80 homolog, putative 501 21 PBANKA_134720 nucleotidyltransferase, putative 502 22 PBANKA_144760 nucleotidyltransferase, putative 503 23 PBANKA_113790 proliferating cell nuclear antigen, putative (PCNA) 504 24 PBANKA_072170 ran binding protein 1, putative 505 25 PBANKA_031600 replication factor C subunit 1, putative 506 26 PBANKA_031470 replication factor C, subunit 2, putative 507 27 PBANKA_094090 RuvB DNA helicase, putative Ubiquitination/ ptoteasome 508 1 PBANKA_133410 20S proteasome beta 4 subunit, putative 509 2 PBANKA_120660 26S proteasome regulatory subunit 4, putative 510 3 PBANKA_041030 26S proteasome regulatory subunit S14, putative 511 4 PBANKA_132970 26S proteasome subunit, putative 512 5 PBANKA_143320 anaphase promoting complex subunit 10, putative 513 6 PBANKA_112680 HECT-domain (ubiquitin-transferase), putative 514 7 PBANKA_082400 OTU-like cysteine protease, putative 515 8 PBANKA_030360 proteasome 26S regulatory subunit, putative 516 9 PBANKA_072030 proteasome regulatory component, putative 517 10 PBANKA_123310 proteasome subunit beta type 1, putative 518 11 PBANKA_134790 ubiquitin activating enzyme, putative 519 12 PBANKA_123150 ubiquitin carboxyl-terminal hydrolase 2, putative ubiquitin carboxyl-terminal hydrolase isozyme L3, putative 520 13 PBANKA_132410 (UCHL3) 521 14 PBANKA_082190 ubiquitin conjugating enzyme, putative 522 15 PBANKA_102970 ubiquitin conjugating enzyme, putative 523 16 PBANKA_102470 ubiquitin fusion degradation protein UFD1, putative 524 17 PBANKA_102090 ubiquitin ligase, putative 525 18 PBANKA_122240 ubiquitin regulatory protein, putative 526 19 PBANKA_091060 ubiquitin related modifier, putative 527 20 PBANKA_041680 ubiquitin specific protease, putative 528 21 PBANKA_144070 ubiquitin-activating enzyme e1, putative 529 22 PBANKA_070410 ubiquitination-mediated degradation component, putative 530 23 PBANKA_124190 ubiquitin-conjugating enzyme E2 N, putative (UBC13) 531 24 PBANKA_010500 ubiquitin-conjugating enzyme e2, putative 532 25 PBANKA_141330 ubiquitin-like protein, putative 533 26 PBANKA_100110 ubiquitin-specific protease, putative Protein folding 534 1 PBANKA_124230 58 kDa phosphoprotein,heat shock-related protein (HRP) 535 2 PBANKA_040460 activator of Hsp90 ATPase, putative (AHA1) 536 3 PBANKA_131740 co-chaperone p23, putative 537 4 PBANKA_133580 disulfide-isomerase, putative 538 5 PBANKA_090580 DnaJ protein, putative 539 6 PBANKA_092200 DnaJ protein, putative 540 7 PBANKA_111990 DnaJ protein, putative 541 8 PBANKA_120380 DnaJ protein, putative 542 9 PBANKA_120390 DnaJ protein, putative 543 10 PBANKA_133640 DnaJ protein, putative 544 11 PBANKA_031000 heat shock 40 kDa protein, putative 545 12 PBANKA_135720 heat shock protein 70 (hsp70), putative 546 13 PBANKA_081890 heat shock protein 70, putative 547 14 PBANKA_121930 heat shock protein 70, putative (HSP70-z) 548 15 PBANKA_080570 heat shock protein 90, putative (HSP90) 549 16 PBANKA_060990 heat shock protein DNAJ homologue Pfj4, putative 550 17 PBANKA_093220 peptidyl-prolyl cis-trans isomerase, putative 551 18 PBANKA_121650 peptidyl-prolyl cis-trans isomerase, putative (CYP19A) 552 19 PBANKA_122720 peptidyl-prolyl cis-trans isomerase, putative (CYP81) 553 20 PBANKA_102580 prefoldin subunit 2, putative 554 21 PBANKA_070280 protein disulfide isomerase 555 22 PBANKA_040520 T-complex protein beta subunit, putative 556 23 PBANKA_091620 TCP-1/cpn60 chaperonin family, putative Transporter 557 1 PBANKA_135330 ABC transporter, putative 558 2 PBANKA_091590 amino acid transporter, putative 559 3 PBANKA_041650 ATPase, putative 560 4 PBANKA_121950 chloroquine resistance transporter, putative (CRT) 561 5 PBANKA_130290 copper transporter, putative 562 6 PBANKA_081570 membrane transporter, putative 563 7 PBANKA_082720 monocarboxylase transporter, putative 564 8 PBANKA_020830 novel putative transporter 1 (NPT1) 565 9 PBANKA_136010 nucleoside transporter 1 (NT1) 566 10 PBANKA_020990 nucleoside transporter, putative 567 11 PBANKA_143400 phosphate translocator, putative 568 12 PBANKA_080630 P-type ATPase, putative 569 13 PBANKA_140200 sodium/hydrogen exchanger, Na , H antiporter, putative 570 14 PBANKA_081700 sugar transporter, putative 571 15 PBANKA_091830 transporter, putative 572 16 PBANKA_133840 vacuolar ATP synthase subunit g, putative 573 17 PBANKA_140510 vacuolar ATP synthase subunit h, putative 574 18 PBANKA_132050 V-type H( )-translocating pyrophosphatase, putative 575 19 PBANKA_050650 zinc transporter, putative Histone modification/chromatin structure 576 1 PBANKA_101840 arginine methyltransferase 1, putative (PRMT1) 577 2 PBANKA_143610 heterochromatin protein 1, putative (HP1) 578 3 PBANKA_071290 high mobility group protein, putative (HMGB2) 579 4 PBANKA_070730 histone acetyltransferase GCN5, putative (GCN5) 580 5 PBANKA_110620 histone deacetylase, putative 581 6 PBANKA_121760 histone H2A variant, putative (H2A.Z) 582 7 PBANKA_111700 histone H2A, putative (H2A) 583 8 PBANKA_142060 histone H2B, putative 584 9 PBANKA_010880 histone H3, putative 585 10 PBANKA_111710 histone H3, putative (H3.3) 586 11 PBANKA_142600 histone-arginine methyltransferase, putative (CARM1) 587 12 PBANKA_072070 regulator of chromosome condensation, putative 558 13 PBANKA_070290 SET domain protein, putative 589 14 PBANKA_081120 SET domain protein, putative 590 15 PBANKA_110770 SET domain protein, putative 591 16 PBANKA_071080 Snf2-related CBP activator, putative (SRCAP) 592 17 PBANKA_082570 telomeric repeat binding factor 1, putative Zinc finger protein 593 1 PBANKA_051200 DHHC-type zinc finger protein, putative 594 2 PBANKA_040830 phd finger protein, putative 595 3 PBANKA_090720 phd finger protein, putative 596 4 PBANKA_031190 RING zinc finger protein, putative 597 5 PBANKA_120680 zinc finger C-x8-C-x5-C-x3-H type, putative 598 6 PBANKA_041240 zinc finger protein, putative 599 7 PBANKA_041270 zinc finger protein, putative 600 8 PBANKA_041360 zinc finger protein, putative 601 9 PBANKA_071230 zinc finger protein, putative 602 10 PBANKA_071270 zinc finger protein, putative 603 11 PBANKA_113480 zinc finger protein, putative 604 12 PBANKA_123270 zinc finger protein, putative 605 13 PBANKA_140880 zinc finger protein, putative 606 14 PBANKA_141970 zinc finger protein, putative 607 15 PBANKA_143340 zinc finger protein, putative 608 16 PBANKA_145800 zinc finger protein, putative Proteolysis 609 1 PBANKA_083310 aspartyl aminopeptidase, putative 610 2 PBANKA_132830 ATP-dependent protease la, putative 611 3 PBANKA_132170 cysteine proteinase, putative 612 4 PBANKA_146070 dipeptidyl peptidase 2, putative (DPAP2) 613 5 PBANKA_130990 leucine aminopeptidase, putative 614 6 PBANKA_113140 metacaspase 1 (MCA1) 615 7 PBANKA_130230 metacaspase-like protein 616 8 PBANKA_102650 metacaspase-like protein (MCA3) 617 9 PBANKA_120780 metallopeptidase, putative 618 10 PBANKA_100650 peptidase, M22 family, putative 619 11 PBANKA_092650 petidase, M16 family, putative 620 12 PBANKA_122250 plasmepsin X 621 13 PBANKA_082010 PPPDE peptidase, putative 622 14 PBANKA_091170 subtilisin-like protease 2 (SUB2) 623 15 PBANKA_110680 subtilisin-like protease 3, putative (SUB3) Preerythrocytic stage 624 1 PBANKA_100210 6-cysteine protein (P36) cell traversal protein for ookinetes and sporozoites 625 2 PBANKA_143230 (CelTOS) 626 3 PBANKA_081240 cysteine repeat modular protein 1 (CRMP1) 627 4 PBANKA_130080 cysteine repeat modular protein 4 (CRMP4) 628 5 PBANKA_140080 early transcribed membrane protein 13 (UIS3) 629 6 PBANKA_040260 inner membrane complex protein 1a (IMC1a) 630 7 PBANKA_010110 liver merozoite formation protein (PALM) 631 8 PBANKA_102460 liver specific protein 1 (LISP1) 632 9 PBANKA_090130.2 merozoite adhesive erythrocytic binding protein (MAEBL) 633 10 PBANKA_100300 sequestrin, putative 634 11 PBANKA_030470 serine repeat antigen 5 (SERA5) 635 12 PBANKA_090210 sporozoite asparagine-rich protein (SLARP) sporozoite surface protein 2,thrombospondin-related 636 13 PBANKA_134980 anonymous protein (TRAP) Gametocyte/ookinete/oocyst 637 1 PBANKA_051500 25 kDa ookinete surface antigen precursor (P25) 638 2 PBANKA_080050 chitinase (CHT1) 639 3 PBANKA_094340 CPW-WPC family protein, putative 640 4 PBANKA_144930 CPW-WPC family protein, putative 641 5 PBANKA_070190 GPI-anchored micronemal antigen, putative (GAMA) 642 6 PBANKA_124070 NIMA related kinase 2 (NEK2) 643 7 PBANKA_060060 NIMA related kinase 3, putative (NEK3) 644 8 PBANKA_061670 NIMA related kinase 4 (NEK4) 645 9 PBANKA_121810 oocyst capsule protein (Cap380) 646 10 PBANKA_103780 secreted ookinete adhesive protein (SOAP) 647 11 PBANKA_061920 secreted ookinete protein, putative (PSOP1) 648 12 PBANKA_090590 transcription factor with AP2 domain(s) (AP2-O) 649 13 PBANKA_122890 von willebrand factor a-domain-related protein (WARP) Motor protein 650 1 PBANKA_050450 cytoplasmic dynein intermediate chain, putative 651 2 PBANKA_060120 dynein heavy chain, putative 652 3 PBANKA_021400 dynein heavy chain, putative 653 4 PBANKA_082830 dynein light chain, putative 654 5 PBANKA_041490 dynein light intermediate chain 2, putative 655 6 PBANKA_101030 dynein-related AAA-type ATPase, putative 656 7 PBANKA_145880 kinesin, putative 657 8 PBANKA_090250 kinesin-like protein, putative 658 9 PBANKA_060950 kinesin-related protein, putative 659 10 PBANKA_144450 myosin D, putative (MyoD) 660 11 PBANKA_090850 myosin heavy chain subunit, putative 661 12 PBANKA_134410 myosin, putative 662 13 PBANKA_011220 myosin-like protein, putative Phospholipid metabolism 663 1 PBANKA_121620 acyl CoA:diacylglycerol acyltransferase, putative 664 2 PBANKA_145330 acyl-CoA synthetase, putative 665 3 PBANKA_092370 ethanolamine kinase, putative 666 4 PBANKA_136050 ethanolamine-phosphate cytidylyltransferase (ECT) 667 5 PBANKA_020130 lysophospholipase, putative 668 6 PBANKA_122020 lysophospholipase, putative 669 7 PBANKA_082490 patatin-like phospholipase, putative 670 8 PBANKA_082870 phosphatidylserine decarboxylase, putative 671 9 PBANKA_112810 phospholipase (PL) 672 10 PBANKA_030620 phospholipase A2, putative 673 11 PBANKA_062320 phospholipase, putative 674 12 PBANKA_142310 phospholipase, putative 675 13 PBANKA_010030 phospholipase, putative, pseudogene Antioxidant 676 1 PBANKA_122800 1-cys peroxiredoxin, putative 677 2 PBANKA_061790 ferrodoxin reductase-like protein, putative 678 3 PBANKA_082410 flavodoxin-like protein 679 4 PBANKA_040470 glutaredoxin 1, putative (GRX1) 680 5 PBANKA_102390 glutathione s-transferase, putative 681 6 PBANKA_111180 glutathione synthetase (GS) 682 7 PBANKA_111630 malate:quinone oxidoreductase, putative 683 8 PBANKA_051140 peroxiredoxin, putative (nPrx) 684 9 PBANKA_082020 thioredoxin, putative 685 10 PBANKA_134500 thioredoxin, putative Purine/pyrimidine biosysthesis 686 1 PBANKA_051360 adenosine deaminase, putative 687 2 PBANKA_133740 adenosine-diphosphatase, putative 688 3 PBANKA_123560 adenosylhomocysteinase, putative (SAHH) 689 4 PBANKA_120720 adenylate kinase, putative (AK1) 690 5 PBANKA_134440 AMP deaminase, putative 691 6 PBANKA_103230 cytidine triphosphate synthetase, putative 692 7 PBANKA_052060 enhancer of rudimentary homolog, putative 693 8 PBANKA_121100 GMP synthetase, putative (GMPS) 694 9 PBANKA_122600 pseudouridylate synthase, putative 695 10 PBANKA_111300 purine nucleotide phosphorylase, putative Glycolysis 696 1 PBANKA_091560 aquaglyceroporin (AQP) 697 2 PBANKA_121430 enolase, putative (ENO) 698 3 PBANKA_132640 glyceraldehyde-3-phosphate dehydrogenase, putative 699 4 PBANKA_134010 L-lactate dehydrogenase (LDH) 700 5 PBANKA_135590 phosphoenolpyruvate carboxykinase, putative (PEPCK) 701 6 PBANKA_082340 phosphoglycerate kinase, putative (PGK) 702 7 PBANKA_092810 phosphoglycerate mutase, putative (PGM1) 703 8 PBANKA_112560 pyruvate kinase, putative 704 9 PBANKA_130380 triose-phosphate isomerase, putative (TIM) Amino acid metabolism 705 1 PBANKA_041480 arginase 706 2 PBANKA_040760 asparagine synthetase, putative 707 3 PBANKA_030230 aspartate aminotransferase, putative 708 4 PBANKA_100950 NAD(P)H-dependent glutamate synthase, putative 709 5 PBANKA_010740 ornithine aminotransferase, putative (OAT) 710 6 PBANKA_113420 pyrroline carboxylate reductase, putative 711 7 PBANKA_082310 S-adenosylmethionine synthetase, putative S-adenosylmethionine-dependent methyltransferase, 712 8 PBANKA_123700 putative Glycosylation 713 1 PBANKA_070420 dehydrodolichyl diphosphate synthetase, putative dolichyl-diphosphooligosaccharide--protein- 714 2 PBANKA_082050 glycosyltransferase, putative 715 3 PBANKA_090160 farnesyltransferase beta subunit, putative 716 4 PBANKA_142850 glycerol-3-phosphate acyltransferase, putative 717 5 PBANKA_093600 inositol-5 phosphatase, putative 718 6 PBANKA_111140 myo-inositol 1-phosphate synthase, putative N-acetylglucosaminylphosphatidylinositol deacetylase, 719 7 PBANKA_112360 putative Protein modification phosphatidylinositol N- acetylglucosaminyltransferase 720 1 PBANKA_083610 subunit P, putative phosphatidylinositol N- acetylglucosaminyltransferase, 721 2 PBANKA_081210 putative 722 3 PBANKA_060930 GPI mannosyltransferase I, putative 723 4 PBANKA_102890 diphthamide synthesis protein, putative 724 5 PBANKA_120730 diphthine synthase, putative 725 6 PBANKA_102980 N-myristoyltransferase, putative Others 726 1 PBANKA_113810 14-3-3 protein, putative 727 2 PBANKA_141980 3',5'-cyclic nucleotide phosphodiesterase, putative 728 3 PBANKA_061750 3'-5' exoribonuclease Csl4 homolog, putative 729 4 PBANKA_145440 3-hydroxyisobutyryl-coenzyme A hydrolase, putative 730 5 PBANKA_080460 AAA family ATPase, putative 731 6 PBANKA_102990 AAA family ATPase, putative 732 7 PBANKA_122670 AAA family ATPase, putative 733 8 PBANKA_131460 acetyl-CoA acetyltransferase, putative 734 9 PBANKA_061680 actin-related protein 735 10 PBANKA_102060 actin-related protein homolog, putative 736 11 PBANKA_110480 actin-related protein, putative 737 12 PBANKA_122760 adenylyl cyclase beta, putative (ACbeta) 738 13 PBANKA_130440 allantoicase, putative 739 14 PBANKA_102030 ankyrin, putative 740 15 PBANKA_131250 Appr-1-p processing domain protein 741 16 PBANKA_020760 asparagine-rich antigen, putative 742 17 PBANKA_142810 asparagine-rich antigen, putative 743 18 PBANKA_143740 ATP-binding protein, putative 744 19 PBANKA_041570 autophagy-related protein 3, putative (ATG3) 745 20 PBANKA_093240 berghepain-2 (BP2) 746 21 PBANKA_051100 biotin--acetyl-CoA-carboxylase, putative 747 22 PBANKA_101060 calmodulin, putative 748 23 PBANKA_071620 calmodulin-like protein, putative 749 24 PBANKA_090510 carbohydrate kinase, putative 750 25 PBANKA_121960 cg1 protein, putative 751 26 PBANKA_104010 choline kinase (CK) 752 27 PBANKA_112700 choline/ethanolaminephosphotransferase (CEPT) 753 28 PBANKA_112190 chorismate synthase, putative (CS) 754 29 PBANKA_092670 circumsporozoite-related antigen 755 30 PBANKA_112200 coronin binding protein, putative 756 31 PBANKA_146410 coronin, putative 757 32 PBANKA_100400 cytosolic glyoxalase II, putative dihydrofolate synthase/folylpolyglutamate synthase, 758 33 PBANKA_134000 putative 759 34 PBANKA_040560 EB1 homolog, putative 760 35 PBANKA_112220 EGF-like membrane protein, putative 761 36 PBANKA_135110 exoribonuclease, putative fatty acid elongation protein, GNS1/SUR4 family, putative, 762 37 PBANKA_020430 pseudogene 763 38 PBANKA_123750 G10 protein, putative geranylgeranyl pyrophosphate synthase, putative 764 39 PBANKA_091980 (GGPPS) glucose-6-phosphate dehydrogenase-6- 765 40 PBANKA_131750 phosphogluconolactonase (G6PD-6PGL) 766 41 PBANKA_093390 glyoxalase I, putative 767 42 PBANKA_124020 G-protein coupled receptor, putative 768 43 PBANKA_040180 HAD superfamily protein, putative 769 44 PBANKA_131060 heme detoxification protein, putative 770 45 PBANKA_131910 hemolysin, putative 771 46 PBANKA_061190 histidine triad protein, putative 772 47 PBANKA_061090 HSP40, subfamily A, putative 773 48 PBANKA_144100 hydrolase/phosphatase, putative 774 49 PBANKA_144980 inorganic pyrophosphatase, putative intra-erythrocytic P. berghei-induced structures protein 1 775 50 PBANKA_136550 (IBIS1) 776 51 PBANKA_130360 leucine carboxyl methyltransferase, putative 777 52 PBANKA_090270 leucine-rich repeat protein (LRR10) 778 53 PBANKA_101250 leucine-rich repeat protein (LRR5) long chain polyunsaturated fatty acid elongation enzyme, 779 54 PBANKA_010470 putative 780 55 PBANKA_144400 macrophage migration inhibitory factor (MIF) 781 56 PBANKA_071960 memo-like protein 782 57 PBANKA_133940 microfibril-associated protein homologue, putative 783 58 PBANKA_112930 microtubule-associated protein ytm1 homologue, putative 784 59 PBANKA_135910 MOG1 homologue, putative 785 60 PBANKA_040750 N2227-like protein, putative 786 61 PBANKA_061180 N-acetyltransferase, putative 787 62 PBANKA_120170 N-acetyltransferase, putative 788 63 PBANKA_134280 nicotinic acid mononucleotide adenyltransferase 789 64 PBANKA_111550 nif-like protein, putative 790 65 PBANKA_135060 nuclear movement protein, putative 791 66 PBANKA_103030 nuclear transport factor 2, putative 792 67 PBANKA_123640 nucleotide binding protein, putative 793 68 PBANKA_121110 phosphatase, putative 794 69 PBANKA_040930 phosphatidylinositol 3- and 4-kinase, putative 795 70 PBANKA_133370 phosphodiesterase delta (PDEdelta) 796 71 PBANKA_141990 phosphodiesterase gamma (PDEgamma) 797 72 PBANKA_071470 phosphopantothenoylcysteine decarboxylase, putative 798 73 PBANKA_101460 phosphotyrosyl phosphatase activator, putative 799 74 PBANKA_083070 procollagen lysine 5-dioxygenase, putative 800 75 PBANKA_123080 pyridoxal kinase-like protein, putative 801 76 PBANKA_112020 pyridoxine biosynthesis protein PDX1, putative (PDX1) 802 77 PBANKA_103530 radical SAM protein, putative 803 78 PBANKA_070750 RWD domain-containing protein, putative 804 79 PBANKA_140480 SAM dependent methyltransferase, putative 805 80 PBANKA_041080 SEL-1 like protein 806 81 PBANKA_141210 septum formation protein MAF homologue, putative 807 82 PBANKA_140300 small heat shock protein, putative 808 83 PBANKA_145310 sphingomyelin phosphodiesterase, putative 809 84 PBANKA_111070 stearoyl-CoA delta 9 desaturase, putative 810 85 PBANKA_144530 sun-family protein, putative 811 86 PBANKA_102250 surface protein, putative 812 87 PBANKA_112980 Tetratricopeptide repeat protein, putative 813 88 PBANKA_092220 ThiF family protein, putative 814 89 PBANKA_052430 tryptophan/threonine-rich antigen, putative 815 90 PBANKA_062330 tryptophan-rich antigen, putative 816 91 PBANKA_052460 unspecified product 817 92 PBANKA_101740 unspecified product (Sel4) 818 93 PBANKA_091130 UVB-resistance protein UVR8 homologue, putative 819 94 PBANKA_060050 XPA binding protein 1, putative 820 95 PBANKA_081870 XPA binding protein 1, putative aTarget genes in Table S6 were classified into several categories according to their putative functions and expressed stages. They were arranged in the same order as shown in the Figure 3G and Figure S4..

Table S8. Genes for merozoite surface proteins and rhoptry proteins in the targetsa

Gene IDb Functional annotation PBANKA_091500 apical membrane antigen 1 (AMA1) PBANKA_072180 apical merozoite protein, putative PBANKA_140060 cytoadherence linked asexual protein, putative PBANKA_133270 duffy-binding protein PBANKA_083100 merozoite surface protein 1 (MSP1) PBANKA_111960 merozoite surface protein 10, putative (MSP10) PBANKA_134910 merozoite surface protein 7 (MSP7) PBANKA_134920 MSP7-like protein (MSRP1) PBANKA_134900 MSP7-like protein (MSRP2) PBANKA_070090 reticulocyte-binding protein, putative PBANKA_070270 rhomboid protease, putative PBANKA_111470 rhomboid protease, putative PBANKA_041600 RhopH3, putative PBANKA_146490 rhoptry neck protein 3, putative (RON3) PBANKA_071310 rhoptry neck protein 5, putative (RON5) PBANKA_031170 rhoptry neck protein 6, putative (RON6) PBANKA_010040 rhoptry protein, putative PBANKA_114230 rhoptry protein, putative PBANKA_133030 rhoptry protein, putative PBANKA_103210 rhoptry-associated protein 1, putative (RAP1) PBANKA_110140 rhoptry-associated protein 2/3 (RAP2/3)

aTarget genes for merozoite surface proteins and rhoptry proteins were selected from the genes belonging to the category “merozoite formation” in Figure 3G and Table S7. bGene ID and functional annotation were attributed to each gene according to those in PlasmoDB. Target genes were sorted in alphabetical order of attributed functional annotations.

Table S9. Genes up-regulated in AP2-G2(–) parasitesa

IDb Functional annotationb target 1 PBANKA_082380 3-oxoacyl-(acyl-carrier protein) reductase, putative yes 3-oxoacyl-acyl-carrier protein synthase, putative 2 PBANKA_112510 yes (FabB/FabF) 3 PBANKA_113120 60S ribosomal protein L7-2, putative yes 4 PBANKA_011110 6-cysteine protein (P12p) 5 PBANKA_091870 A/G-specific adenine glycosylase, putative yes 6 PBANKA_131460 acetyl-CoA acetyltransferase, putative yes 7 PBANKA_122520 acetyltransferase, putative 8 PBANKA_030560 acyl carrier protein, putative (ACP) yes 9 PBANKA_122760 adenylyl cyclase beta, putative (ACbeta) yes 10 PBANKA_120310 ADP/ATP carrier protein, putative 11 PBANKA_100290 ag-1 blood stage membrane protein homologue yes apicoplast beta-ketoacyl-acyl carrier protein 12 PBANKA_030820 synthase III precursor, putative apicoplast glycerol-3-phosphate acyltransferase, 13 PBANKA_141670 yes putative apicoplast RNA methyltransferase precursor, 14 PBANKA_031500 putative 15 PBANKA_041480 arginase yes 16 PBANKA_143740 ATP-binding protein, putative yes 17 PBANKA_102410 ATP-dependent RNA helicase, putative yes beta-hydroxyacyl-ACP dehydratase, putative 18 PBANKA_133820 yes (FabZ) 19 PBANKA_051100 biotin--acetyl-CoA-carboxylase, putative yes 20 PBANKA_135150 calcium dependent protein kinase 5 (CDPK5) yes 21 PBANKA_102440 calmodulin, putative 22 PBANKA_040320 circumsporozoite (CS) protein (CSP) 23 PBANKA_070920 clp1-related protein, putative yes conserved Plasmodium membrane protein, 24 PBANKA_051890 unknown function 25 PBANKA_051950 conserved Plasmodium protein, unknown function yes 26 PBANKA_146260 conserved Plasmodium protein, unknown function 27 PBANKA_050180 conserved Plasmodium protein, unknown function yes 28 PBANKA_134090 conserved Plasmodium protein, unknown function yes 29 PBANKA_070660 conserved Plasmodium protein, unknown function 30 PBANKA_141150 conserved Plasmodium protein, unknown function yes 31 PBANKA_135460 conserved Plasmodium protein, unknown function yes 32 PBANKA_145120 conserved Plasmodium protein, unknown function 33 PBANKA_080950 conserved Plasmodium protein, unknown function yes 34 PBANKA_111760 conserved Plasmodium protein, unknown function 35 PBANKA_120290 conserved Plasmodium protein, unknown function 36 PBANKA_132420 conserved Plasmodium protein, unknown function yes 37 PBANKA_141370 conserved Plasmodium protein, unknown function yes 38 PBANKA_090980 conserved Plasmodium protein, unknown function 39 PBANKA_142300 conserved Plasmodium protein, unknown function yes 40 PBANKA_081960 conserved Plasmodium protein, unknown function yes 41 PBANKA_080810 conserved Plasmodium protein, unknown function yes 42 PBANKA_092140 conserved Plasmodium protein, unknown function yes 43 PBANKA_100230 conserved Plasmodium protein, unknown function 44 PBANKA_090280 conserved Plasmodium protein, unknown function yes 45 PBANKA_020890 conserved Plasmodium protein, unknown function yes 46 PBANKA_090860 conserved Plasmodium protein, unknown function 47 PBANKA_103740 conserved Plasmodium protein, unknown function yes 48 PBANKA_070770 conserved Plasmodium protein, unknown function yes 49 PBANKA_040660 conserved Plasmodium protein, unknown function yes 50 PBANKA_120070 conserved Plasmodium protein, unknown function 51 PBANKA_131120 conserved Plasmodium protein, unknown function yes 52 PBANKA_091190 conserved Plasmodium protein, unknown function yes 53 PBANKA_020780 conserved Plasmodium protein, unknown function 54 PBANKA_061390 conserved Plasmodium protein, unknown function yes 55 PBANKA_140860 conserved Plasmodium protein, unknown function yes 56 PBANKA_135160 conserved Plasmodium protein, unknown function 57 PBANKA_140600 conserved Plasmodium protein, unknown function yes 58 PBANKA_031340 conserved Plasmodium protein, unknown function 59 PBANKA_083220 conserved Plasmodium protein, unknown function yes 60 PBANKA_133150 conserved Plasmodium protein, unknown function yes 61 PBANKA_134080 conserved Plasmodium protein, unknown function yes 62 PBANKA_133050 conserved Plasmodium protein, unknown function yes 63 PBANKA_110200 conserved Plasmodium protein, unknown function yes 64 PBANKA_102160 conserved Plasmodium protein, unknown function 65 PBANKA_135740 conserved Plasmodium protein, unknown function 66 PBANKA_145470 conserved Plasmodium protein, unknown function yes 67 PBANKA_141590 conserved Plasmodium protein, unknown function 68 PBANKA_140210 conserved Plasmodium protein, unknown function yes 69 PBANKA_040690 conserved Plasmodium protein, unknown function yes 70 PBANKA_021370 conserved Plasmodium protein, unknown function yes 71 PBANKA_062230 conserved Plasmodium protein, unknown function yes 72 PBANKA_071690 conserved Plasmodium protein, unknown function yes 73 PBANKA_124240 conserved Plasmodium protein, unknown function yes 74 PBANKA_030240 conserved Plasmodium protein, unknown function 75 PBANKA_080420 conserved Plasmodium protein, unknown function yes 76 PBANKA_081480 conserved Plasmodium protein, unknown function yes 77 PBANKA_081760 conserved Plasmodium protein, unknown function yes 78 PBANKA_145810 conserved Plasmodium protein, unknown function yes 79 PBANKA_113030 conserved Plasmodium protein, unknown function yes 80 PBANKA_092610 conserved Plasmodium protein, unknown function 81 PBANKA_133600 conserved Plasmodium protein, unknown function 82 PBANKA_092020 conserved Plasmodium protein, unknown function conserved Plasmodium protein, unknown function 83 PBANKA_143600 yes (UIS27) 84 PBANKA_070160 conserved protein, unknown function 85 PBANKA_101700 CorA-like Mg2 transporter protein, putative 86 PBANKA_081240 cysteine repeat modular protein 1 (CRMP1) yes 87 PBANKA_130080 cysteine repeat modular protein 4 (CRMP4) yes 88 PBANKA_060260 cytochrome c1 heme lyase, putative yes 89 PBANKA_145520 DEAD/DEAH helicase, putative 90 PBANKA_145920 delta-aminolevulinic acid synthetase, putative 91 PBANKA_103000 deoxyhypusine synthase, putative yes dihydrofolate synthase/folylpolyglutamate 92 PBANKA_134000 yes synthase, putative 93 PBANKA_050500 dihydrolipoamide acyltransferase, putative yes 94 PBANKA_102890 diphthamide synthesis protein, putative yes 95 PBANKA_082390 DNA-directed RNA polymerase II, putative yes 96 PBANKA_133270 duffy-binding protein yes 97 PBANKA_140080 early transcribed membrane protein 13 (UIS3) yes 98 PBANKA_122980 enoyl-acyl carrier reductase (FABI) yes 99 PBANKA_070650 exonuclease, putative 100 PBANKA_090160 farnesyltransferase beta subunit, putative yes 101 PBANKA_123750 G10 protein, putative yes 102 PBANKA_121240 GDP-fucose synthase, putative 103 PBANKA_010550 glutaredoxin-like protein (GLP2) 104 PBANKA_093290 glycerol-3-phosphate dehydrogenase, putative yes 105 PBANKA_093390 glyoxalase I, putative yes golgi re-assembly stacking protein, putative 106 PBANKA_050160 yes (GRASP) GPI-anchored micronemal antigen, putative 107 PBANKA_070190 yes (GAMA) 108 PBANKA_110620 histone deacetylase, putative yes histone-arginine methyltransferase, putative 109 PBANKA_142600 yes (CARM1) 110 PBANKA_144980 inorganic pyrophosphatase, putative yes 111 PBANKA_146250 leucine-rich repeat protein (LRR12) 112 PBANKA_071490 lipoamide dehydrogenase, putative 113 PBANKA_070700 lipoate-protein ligase (LipB) 114 PBANKA_135750 lipoyl synthase (LipA) 115 PBANKA_010110 liver merozoite formation protein (PALM) yes 116 PBANKA_082090 long chain fatty acid elongation enzyme, putative malonyl CoA-acyl carrier protein transacylase 117 PBANKA_141050 yes precursor, putative mitochondrial ribosomal protein L21 precursor, 118 PBANKA_102130 putative 119 PBANKA_020440 mRNA cleavage factor-like protein, putative NADP-specific glutamate dehydrogenase, 120 PBANKA_101400 yes putative (GDH2) 121 PBANKA_071480 nucleolar preribosomal assembly protein, putative yes 122 PBANKA_020990 nucleoside transporter, putative yes 123 PBANKA_121810 oocyst capsule protein (Cap380) yes peptidyl-prolyl cis-trans isomerase, putative 124 PBANKA_143100 (CYP32) 125 PBANKA_100630 perforin like protein 1 (SPECT2) 126 PBANKA_112810 phospholipase (PL) yes phosphopantothenoylcysteine decarboxylase, 127 PBANKA_071470 yes putative 128 PBANKA_114540 Plasmodium exported protein, unknown function yes 129 PBANKA_120710 Plasmodium exported protein, unknown function yes 130 PBANKA_011090 PP-loop family protein, putative yes 131 PBANKA_082010 PPPDE peptidase, putative yes 132 PBANKA_144560 protein kinase, putative yes protein-S-isoprenylcysteine O-methyltransferase, 133 PBANKA_145140 putative 134 PBANKA_113420 pyrroline carboxylate reductase, putative yes 135 PBANKA_131010 pyruvate dehydrogenase E1 beta subunit, putative yes pyruvate dehydrogenase E1 component, alpha 136 PBANKA_092380 yes subunit, putative 137 PBANKA_061510 queuine tRNA-ribosyltransferase, putative yes 138 PBANKA_103530 radical SAM protein, putative yes 139 PBANKA_031170 rhoptry neck protein 6, putative (RON6) yes 140 PBANKA_010040 rhoptry protein, putative yes 141 PBANKA_102190 RNA polymerase subunit, putative yes 142 PBANKA_102740 RNA-binding protein, putative S-adenosylmethionine-dependent 143 PBANKA_123700 yes methyltransferase, putative secreted protein with altered thrombospondin 144 PBANKA_030950 repeat domain, putative (SPATR) septum formation protein MAF homologue, 145 PBANKA_141210 yes putative 146 PBANKA_100300 sequestrin, putative yes 147 PBANKA_030470 serine repeat antigen 5 (SERA5) yes 148 PBANKA_081120 SET domain protein, putative yes 149 PBANKA_100390 sexual stage-specific protein precursor, putative 150 PBANKA_140300 small heat shock protein, putative yes 151 PBANKA_070930 small ribosomal subunit processing yes microtubule-associated protein, putative 152 PBANKA_144040 small subunit rRNA processing factor, putative yes 153 PBANKA_090210 sporozoite asparagine-rich protein (SLARP) yes sporozoite surface protein 154 PBANKA_134980 2,thrombospondin-related anonymous protein yes (TRAP) TFIIH basal transcription factor subunit, putative 155 PBANKA_141340 yes (UIS23) transcription factor with AP2 domain(s), putative 156 PBANKA_136370 (ApiAP2) transcription factor with AP2 domain(s), putative 157 PBANKA_100180 yes (ApiAP2) 158 PBANKA_130650 TRAP-like protein (TREP) 159 PBANKA_051880 tRNA pseudouridine synthase D, putative yes 160 PBANKA_103360 tRNA-dihydrouridine synthase, putative 161 PBANKA_142260 unspecified product (Sel3) UVB-resistance protein UVR8 homologue, 162 PBANKA_091130 yes putative 163 PBANKA_041240 zinc finger protein, putative yes 164 PBANKA_071270 zinc finger protein, putative yes

aDNA microarray analysis was performed between wild-type and AP2-G2(−) parasites using rats synchronously infected with P. berghei parasites. Infected blood was harvested 19 h after intravenous inoculation of cultured schizonts into rats.Genes upregulated more than twofold in AP2-G2(−) parasites are listed. bGene ID and functional annotation were attributed to each gene according to those in PlasmoDB. Target genes were sorted in alphabetical order of attributed functional annotations.

Table S10. Sequences enriched in upstream regions of genes up-regulated in AP2-G2(–) parasitesa

six base sequence p-value motif 1 CAACCAb 2.78E-08 (A/G) CAAC 2 GGTTGC 1.59E-07 GTTG(T/C) 3 TGGTTG 4.71E-07 GTTG(T/C) 4 AACCAA 2.47E-06 5 GTTGTA 4.23E-06 GTTG(T/C) 6 GATCGG 8.12E-06 7 GTTGCA 1.59E-05 GTTG(T/C) 8 ACAACC 1.62E-05 (A/G) CAAC 9 GGTTGT 2.22E-05 GTTG(T/C) 10 TGTTCA 2.23E-05 11 TGCAAC 3.63E-05 (A/G) CAAC 12 TACAAC 5.89E-05 (A/G) CAAC 13 CAACAC 6.04E-05 (A/G) CAAC 14 GTTCTG 7.76E-05 15 TGTTGC 0.00011 GTTG(T/C) 16 GCAACC 0.000186 (A/G) CAAC 17 ACAACT 0.000344 (A/G) CAAC 18 CACTTC 0.000474 19 AGCTGG 0.000573 20 TGTAGA 0.000594 aFisher’s exact test was performed in all six base sequences between upstream regions of genes listed in S9 and those of other P. berghei genes. bThe result is arranged from the sequence with the smallest p-value.

Table S11. Classification of genes up-regulated in AP2-G2(–) parasitesa

Gene IDb Functional annotationb Organella 3-oxoacyl-(acyl-carrier protein) reductase, 1 1 PBANKA_082380 putative 3-oxoacyl-acyl-carrier protein synthase, putative 2 2 PBANKA_112510 (FabB/FabF) 3 3 PBANKA_091870 A/G-specific adenine glycosylase, putative 4 4 PBANKA_030560 acyl carrier protein, putative (ACP) 5 5 PBANKA_120310 ADP/ATP carrier protein, putative apicoplast beta-ketoacyl-acyl carrier protein 6 6 PBANKA_030820 synthase III precursor, putative apicoplast glycerol-3-phosphate acyltransferase, 7 7 PBANKA_141670 putative apicoplast RNA methyltransferase precursor, 8 8 PBANKA_031500 putative beta-hydroxyacyl-ACP dehydratase, putative 9 9 PBANKA_133820 (FabZ) 10 10 PBANKA_101700 CorA-like Mg2 transporter protein, putative 11 11 PBANKA_060260 cytochrome c1 heme lyase, putative 12 12 PBANKA_050500 dihydrolipoamide acyltransferase, putative 13 13 PBANKA_122980 enoyl-acyl carrier reductase (FABI) 14 14 PBANKA_093290 glycerol-3-phosphate dehydrogenase, putative 15 15 PBANKA_071490 lipoamide dehydrogenase, putative 16 16 PBANKA_070700 lipoate-protein ligase (LipB) 17 17 PBANKA_135750 lipoyl synthase (LipA) malonyl CoA-acyl carrier protein transacylase 18 18 PBANKA_141050 precursor, putative mitochondrial ribosomal protein L21 precursor, 19 19 PBANKA_102130 putative NADP-specific glutamate dehydrogenase, 20 20 PBANKA_101400 putative (GDH2) 21 21 PBANKA_131010 pyruvate dehydrogenase E1 beta subunit, putative pyruvate dehydrogenase E1 component, alpha 22 22 PBANKA_092380 subunit, putative 23 23 PBANKA_142260 unspecified product (Sel3) Oocyst and preerythrocytic stages 24 1 PBANKA_040320 circumsporozoite (CS) protein (CSP) 25 2 PBANKA_081240 cysteine repeat modular protein 1 (CRMP1) 26 3 PBANKA_130080 cysteine repeat modular protein 4 (CRMP4) 27 4 PBANKA_140080 early transcribed membrane protein 13 (UIS3) GPI-anchored micronemal antigen, putative 28 5 PBANKA_070190 (GAMA) 29 6 PBANKA_010110 liver merozoite formation protein (PALM) 30 7 PBANKA_121810 oocyst capsule protein (Cap380) 31 8 PBANKA_100630 perforin like protein 1 (SPECT2) 32 9 PBANKA_112810 phospholipase (PL) 33 10 PBANKA_100300 sequestrin, putative 34 11 PBANKA_030470 serine repeat antigen 5 (SERA5) 35 12 PBANKA_090210 sporozoite asparagine-rich protein (SLARP) sporozoite surface protein 36 13 PBANKA_134980 2,thrombospondin-related anonymous protein (TRAP) 37 14 PBANKA_130650 TRAP-like protein (TREP) Protein biosynthesis 38 1 PBANKA_113120 60S ribosomal protein L7-2, putative 39 2 PBANKA_070920 clp1-related protein, putative 40 3 PBANKA_103000 deoxyhypusine synthase, putative 41 4 PBANKA_020440 mRNA cleavage factor-like protein, putative 42 5 PBANKA_071480 nucleolar preribosomal assembly protein, putative 43 6 PBANKA_011090 PP-loop family protein, putative 44 7 PBANKA_061510 queuine tRNA-ribosyltransferase, putative small ribosomal subunit processing 45 8 PBANKA_070930 microtubule-associated protein, putative 46 9 PBANKA_144040 small subunit rRNA processing factor, putative 47 10 PBANKA_051880 tRNA pseudouridine synthase D, putative 48 11 PBANKA_103360 tRNA-dihydrouridine synthase, putative Transcription 49 1 PBANKA_082390 DNA-directed RNA polymerase II, putative 50 2 PBANKA_102190 RNA polymerase subunit, putative TFIIH basal transcription factor subunit, putative 51 3 PBANKA_141340 (UIS23) transcription factor with AP2 domain(s), putative 52 4 PBANKA_100180 (ApiAP2) transcription factor with AP2 domain(s), putative 53 5 PBANKA_136370 (ApiAP2) Merozoite formation 54 1 PBANKA_011110 6-cysteine protein (P12p) 55 2 PBANKA_135150 calcium dependent protein kinase 5 (CDPK5) 56 3 PBANKA_133270 duffy-binding protein 57 4 PBANKA_031170 rhoptry neck protein 6, putative (RON6) 58 5 PBANKA_010040 rhoptry protein, putative RNA binding 59 1 PBANKA_102410 ATP-dependent RNA helicase, putative 60 2 PBANKA_145520 DEAD/DEAH helicase, putative 61 3 PBANKA_102740 RNA-binding protein, putative Chromatin structure 62 1 PBANKA_110620 histone deacetylase, putative 2 histone-arginine methyltransferase, putative 63 PBANKA_142600 (CARM1) 64 3 PBANKA_081120 SET domain protein, putative Protein vesicular protein transport 1 golgi re-assembly stacking protein, putative 65 PBANKA_050160 (GRASP) others 66 1 PBANKA_131460 acetyl-CoA acetyltransferase, putative 67 2 PBANKA_122520 acetyltransferase, putative 68 3 PBANKA_122760 adenylyl cyclase beta, putative (ACbeta) 69 4 PBANKA_100290 ag-1 blood stage membrane protein homologue 70 5 PBANKA_041480 arginase 71 6 PBANKA_143740 ATP-binding protein, putative 72 7 PBANKA_051100 biotin--acetyl-CoA-carboxylase, putative 73 8 PBANKA_102440 calmodulin, putative 74 9 PBANKA_145920 delta-aminolevulinic acid synthetase, putative dihydrofolate synthase/folylpolyglutamate 75 10 PBANKA_134000 synthase, putative 76 11 PBANKA_102890 diphthamide synthesis protein, putative 77 12 PBANKA_070650 exonuclease, putative 78 13 PBANKA_090160 farnesyltransferase beta subunit, putative 79 14 PBANKA_123750 G10 protein, putative 80 15 PBANKA_121240 GDP-fucose synthase, putative 81 16 PBANKA_010550 glutaredoxin-like protein (GLP2) 82 17 PBANKA_093390 glyoxalase I, putative 83 18 PBANKA_144980 inorganic pyrophosphatase, putative 84 19 PBANKA_146250 leucine-rich repeat protein (LRR12) 85 20 PBANKA_082090 long chain fatty acid elongation enzyme, putative 86 21 PBANKA_020990 nucleoside transporter, putative peptidyl-prolyl cis-trans isomerase, putative 87 22 PBANKA_143100 (CYP32) phosphopantothenoylcysteine decarboxylase, 88 23 PBANKA_071470 putative 89 24 PBANKA_114540 Plasmodium exported protein, unknown function 90 25 PBANKA_120710 Plasmodium exported protein, unknown function 91 26 PBANKA_082010 PPPDE peptidase, putative 92 27 PBANKA_144560 protein kinase, putative protein-S-isoprenylcysteine O-methyltransferase, 93 28 PBANKA_145140 putative 94 29 PBANKA_113420 pyrroline carboxylate reductase, putative 95 30 PBANKA_103530 radical SAM protein, putative S-adenosylmethionine-dependent 96 31 PBANKA_123700 methyltransferase, putative secreted protein with altered thrombospondin 97 32 PBANKA_030950 repeat domain, putative (SPATR) septum formation protein MAF homologue, 98 33 PBANKA_141210 putative 99 34 PBANKA_100390 sexual stage-specific protein precursor, putative 100 35 PBANKA_140300 small heat shock protein, putative UVB-resistance protein UVR8 homologue, 101 36 PBANKA_091130 putative 102 37 PBANKA_041240 zinc finger protein, putative 103 38 PBANKA_071270 zinc finger protein, putative 3-oxoacyl-(acyl-carrier protein) reductase, 104 39 PBANKA_082380 putative aGenes listed in S9 are classified into each category based on attributed functional annotations. bTarget genes were sorted in alphabetical order of attributed functional annotations in each category.

Table S12. Genes up-regulated in AP2-G2(–) parasitesa

IDb Functional annotationb target

1 PBANKA_133060 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative yes

2 PBANKA_135100 1-deoxy-D-xylulose 5-phosphate synthase, putative

3 PBANKA_133410 20S proteasome beta 4 subunit, putative yes

4 PBANKA_091900 26S proteasome regulatory complex subunit, putative

5 PBANKA_081390 26S proteasome regulatory subunit, putative

6 PBANKA_103960 26S proteasome regulatory subunit, putative (RPN6)

7 PBANKA_050220 26s proteasome subunit p55, putative

8 PBANKA_030630 3' exoribonuclease, putative

9 PBANKA_141980 3',5'-cyclic nucleotide phosphodiesterase, putative yes

10 PBANKA_082380 3-oxoacyl-(acyl-carrier protein) reductase, putative yes

11 PBANKA_112510 3-oxoacyl-acyl-carrier protein synthase, putative (FabB/FabF) yes

12 PBANKA_100680 40S ribosomal processing protein, putative

13 PBANKA_140680 40S ribosomal protein S27, putative

14 PBANKA_102930 40S ribosomal protein S9A, putative

15 PBANKA_130210 50S ribosomal protein L20, putative

16 PBANKA_144680 60 kDa chaperonin, putative (CPN60) yes

17 PBANKA_091810 60S ribosomal protein L38e, putative yes

18 PBANKA_133830 60S ribosomal protein L6, putative yes

19 PBANKA_040550 60S ribosomal protein L7, putative yes

20 PBANKA_113120 60S ribosomal protein L7-2, putative yes

21 PBANKA_021340 60S ribosomal subunit export protein, putative yes

22 PBANKA_011100 6-cysteine protein (P12)

23 PBANKA_011110 6-cysteine protein (P12p)

24 PBANKA_100220 6-cysteine protein (P36p)

25 PBANKA_081640 6-phosphofructokinase, putative (PFK9)

26 PBANKA_131840 6-phosphogluconate dehydrogenase, decarboxylating, putative

27 PBANKA_112670 6-pyruvoyltetrahydropterin synthase, putative

28 PBANKA_091870 A/G-specific adenine glycosylase, putative yes

29 PBANKA_080460 AAA family ATPase, putative yes

30 PBANKA_100550 AAA family ATPase, putative

31 PBANKA_102990 AAA family ATPase, putative yes

32 PBANKA_142380 ABC transporter, putative 33 PBANKA_131460 acetyl-CoA acetyltransferase, putative yes

34 PBANKA_112650 acetyl-CoA synthetase, putative

35 PBANKA_122520 acetyltransferase, putative

36 PBANKA_093690 actin-like protein, putative

37 PBANKA_061680 actin-related protein yes

38 PBANKA_102060 actin-related protein homolog, putative yes

39 PBANKA_094330 actin-related protein, putative

40 PBANKA_030560 acyl carrier protein, putative (ACP) yes

41 PBANKA_121620 acyl CoA:diacylglycerol acyltransferase, putative yes

42 PBANKA_111870 acyl-CoA synthetase, putative

43 PBANKA_092910 acyl-CoA-binding protein, putative

44 PBANKA_021430 adapter-related protein, putative yes

45 PBANKA_130460 adaptor complexes medium subunit family yes

46 PBANKA_146340 adaptor-related protein complex 3, sigma 2 subunit, putative yes

47 PBANKA_123560 adenosylhomocysteinase, putative (SAHH) yes

48 PBANKA_020280 adenylate kinase, putative

49 PBANKA_030430 adenylosuccinate lyase, putative

50 PBANKA_122760 adenylyl cyclase beta, putative (ACbeta) yes

51 PBANKA_120310 ADP/ATP carrier protein, putative

52 PBANKA_090930 adrenodoxin reductase, putative

53 PBANKA_100290 ag-1 blood stage membrane protein homologue yes

alanine--tRNA ligase, putative,alanyl-tRNA synthetase, putative 54 PBANKA_114360 yes (AlaRS)

55 PBANKA_112830 amino acid transporter, putative

56 PBANKA_135700 aminomethyl transferase, putative

57 PBANKA_114130 aminomethyltransferase, putative

58 PBANKA_134440 AMP deaminase, putative yes

59 PBANKA_100360 apical sushi protein, putative (ASP)

60 PBANKA_146280 apicoplast dimethyladenosine synthase, putative

61 PBANKA_141670 apicoplast glycerol-3-phosphate acyltransferase, putative yes

62 PBANKA_101560 apicoplast ribosomal protein L15 precursor, putative

63 PBANKA_070320 apicoplast ribosomal protein L21 precursor, putative

64 PBANKA_132460 apicoplast ribosomal protein S10 precursor, putative

65 PBANKA_031500 apicoplast RNA methyltransferase precursor, putative

66 PBANKA_124380 apicoplast TIC22 precursor, putative 67 PBANKA_041480 arginase yes

68 PBANKA_113710 arginine methyltransferase 5, putative

69 PBANKA_143420 arginyl-tRNA synthetase, putative

70 PBANKA_020660 asparagine and aspartate rich protein 2, putative

71 PBANKA_093720 asparagine-rich antigen, putative

72 PBANKA_144650 asparagine-rich protein, putative

73 PBANKA_021020 aspartyl-tRNA synthetase, putative yes

74 PBANKA_010090 ATP dependent RNA helicase, putative

75 PBANKA_020950 ATP dependent RNA helicase, putative

76 PBANKA_041650 ATPase, putative yes

77 PBANKA_071700 ATPase, putative

78 PBANKA_061200 ATP-dependent Clp protease proteolytic subunit, putative yes

79 PBANKA_112260 ATP-dependent DEAD box helicase, putative

80 PBANKA_140120 ATP-dependent DEAD box helicase, putative yes

81 PBANKA_080890 ATP-dependent protease ATPase subunit ClpY, putative (ClpY)

82 PBANKA_132270 ATP-dependent RNA helicase DBP5, putative yes

83 PBANKA_123330 ATP-dependent RNA helicase DDX23, putative (DDX23)

84 PBANKA_070950 ATP-dependent RNA helicase prh1, putative yes

85 PBANKA_030680 ATP-dependent RNA helicase UAP56, putative (UAP56)

86 PBANKA_100270 ATP-dependent RNA helicase, putative yes

87 PBANKA_102410 ATP-dependent RNA helicase, putative yes

88 PBANKA_121690 ATP-dependent RNA helicase, putative

89 PBANKA_041670 bacterial histone-like protein, putative (HU)

90 PBANKA_010200 bcs1-like protein, putative yes

91 PBANKA_093240 berghepain-2 (BP2) yes

92 PBANKA_072060 Bet3 transport protein, putative yes

93 PBANKA_020540 beta3 proteasome subunit, putative

94 PBANKA_091010 beta-catenin-like protein 1, putative

95 PBANKA_133820 beta-hydroxyacyl-ACP dehydratase, putative (FabZ) yes

96 PBANKA_142960 bi-functional aminoacyl-tRNA synthetase, putative yes

97 PBANKA_051100 biotin--acetyl-CoA-carboxylase, putative yes

98 PBANKA_103640 BOP1-like protein, putative yes

99 PBANKA_102440 calmodulin, putative

100 PBANKA_140670 carbamoyl phosphate synthetase, putative

101 PBANKA_021190 cation transporting ATPase, putative yes 102 PBANKA_110360 cation transporting P-ATPase, putative (ATPase3)

103 PBANKA_051910 CCAT-binding transcription factor-like protein, putative yes

104 PBANKA_051920 CCAT-binding transcription factor-like protein, putative yes

105 PBANKA_101080 CCR4-associated factor 16, putative (CAF16)

106 PBANKA_094310 CCR4-NOT transcription complex subunit 1, putative (NOT1) yes

107 PBANKA_080800 cdc2-related protein kinase 4 (CRK4)

108 PBANKA_062000 cell cycle control protein cwf15, putative

109 PBANKA_145410 cell division protein FtsH, putative

110 PBANKA_121980 Cg2 protein, putative

111 PBANKA_121940 Cg3 protein, putative yes

112 PBANKA_100820 cGMP-dependent protein kinase (PKG)

113 PBANKA_010730 chaperone, putative

114 PBANKA_080050 chitinase (CHT1) yes

115 PBANKA_121950 chloroquine resistance transporter, putative (CRT) yes

116 PBANKA_112700 choline/ethanolaminephosphotransferase (CEPT) yes

117 PBANKA_112190 chorismate synthase, putative (CS) yes

118 PBANKA_070920 clp1-related protein, putative yes

119 PBANKA_090390 coat protein, gamma subunit, putative

120 PBANKA_091370 coatomer delta subunit, putative

121 PBANKA_051890 conserved Plasmodium membrane protein, unknown function

122 PBANKA_100330 conserved Plasmodium membrane protein, unknown function yes

123 PBANKA_010160 conserved Plasmodium protein, unknown function

124 PBANKA_010220 conserved Plasmodium protein, unknown function

125 PBANKA_010640 conserved Plasmodium protein, unknown function

126 PBANKA_010650 conserved Plasmodium protein, unknown function

127 PBANKA_010670 conserved Plasmodium protein, unknown function

128 PBANKA_010690 conserved Plasmodium protein, unknown function

129 PBANKA_010890 conserved Plasmodium protein, unknown function yes

130 PBANKA_011030 conserved Plasmodium protein, unknown function

131 PBANKA_011240 conserved Plasmodium protein, unknown function yes

132 PBANKA_020200 conserved Plasmodium protein, unknown function

133 PBANKA_020690 conserved Plasmodium protein, unknown function yes

134 PBANKA_020780 conserved Plasmodium protein, unknown function

135 PBANKA_020850 conserved Plasmodium protein, unknown function

136 PBANKA_020890 conserved Plasmodium protein, unknown function yes 137 PBANKA_021080 conserved Plasmodium protein, unknown function

138 PBANKA_030240 conserved Plasmodium protein, unknown function

139 PBANKA_030520 conserved Plasmodium protein, unknown function

140 PBANKA_030940 conserved Plasmodium protein, unknown function

141 PBANKA_030960 conserved Plasmodium protein, unknown function

142 PBANKA_031020 conserved Plasmodium protein, unknown function

143 PBANKA_031040 conserved Plasmodium protein, unknown function

144 PBANKA_031120 conserved Plasmodium protein, unknown function yes

145 PBANKA_031280 conserved Plasmodium protein, unknown function

146 PBANKA_031340 conserved Plasmodium protein, unknown function

147 PBANKA_040340 conserved Plasmodium protein, unknown function

148 PBANKA_040380 conserved Plasmodium protein, unknown function yes

149 PBANKA_040450 conserved Plasmodium protein, unknown function

150 PBANKA_040660 conserved Plasmodium protein, unknown function yes

151 PBANKA_040960 conserved Plasmodium protein, unknown function yes

152 PBANKA_041370 conserved Plasmodium protein, unknown function yes

153 PBANKA_041420 conserved Plasmodium protein, unknown function yes

154 PBANKA_041590 conserved Plasmodium protein, unknown function

155 PBANKA_041790 conserved Plasmodium protein, unknown function

156 PBANKA_050140 conserved Plasmodium protein, unknown function yes

157 PBANKA_050150 conserved Plasmodium protein, unknown function yes

158 PBANKA_050180 conserved Plasmodium protein, unknown function yes

159 PBANKA_050190 conserved Plasmodium protein, unknown function

160 PBANKA_050260 conserved Plasmodium protein, unknown function yes

161 PBANKA_050470 conserved Plasmodium protein, unknown function

162 PBANKA_050490 conserved Plasmodium protein, unknown function yes

163 PBANKA_050530 conserved Plasmodium protein, unknown function yes

164 PBANKA_050550 conserved Plasmodium protein, unknown function

165 PBANKA_050610 conserved Plasmodium protein, unknown function

166 PBANKA_050680 conserved Plasmodium protein, unknown function yes

167 PBANKA_050750 conserved Plasmodium protein, unknown function

168 PBANKA_050820 conserved Plasmodium protein, unknown function yes

169 PBANKA_050890 conserved Plasmodium protein, unknown function

170 PBANKA_050960 conserved Plasmodium protein, unknown function

171 PBANKA_051070 conserved Plasmodium protein, unknown function yes 172 PBANKA_051160 conserved Plasmodium protein, unknown function

173 PBANKA_051210 conserved Plasmodium protein, unknown function

174 PBANKA_051510 conserved Plasmodium protein, unknown function yes

175 PBANKA_051560 conserved Plasmodium protein, unknown function

176 PBANKA_051930 conserved Plasmodium protein, unknown function yes

177 PBANKA_051940 conserved Plasmodium protein, unknown function yes

178 PBANKA_051950 conserved Plasmodium protein, unknown function yes

179 PBANKA_052110 conserved Plasmodium protein, unknown function

180 PBANKA_052410 conserved Plasmodium protein, unknown function

181 PBANKA_052440 conserved Plasmodium protein, unknown function yes

182 PBANKA_060170 conserved Plasmodium protein, unknown function yes

183 PBANKA_060340 conserved Plasmodium protein, unknown function yes

184 PBANKA_060350 conserved Plasmodium protein, unknown function yes

185 PBANKA_060400 conserved Plasmodium protein, unknown function

186 PBANKA_060450 conserved Plasmodium protein, unknown function yes

187 PBANKA_060490 conserved Plasmodium protein, unknown function yes

188 PBANKA_060660 conserved Plasmodium protein, unknown function

189 PBANKA_060750 conserved Plasmodium protein, unknown function

190 PBANKA_060870 conserved Plasmodium protein, unknown function

191 PBANKA_060890 conserved Plasmodium protein, unknown function

192 PBANKA_061210 conserved Plasmodium protein, unknown function

193 PBANKA_061250 conserved Plasmodium protein, unknown function

194 PBANKA_061390 conserved Plasmodium protein, unknown function yes

195 PBANKA_061400 conserved Plasmodium protein, unknown function yes

196 PBANKA_061410 conserved Plasmodium protein, unknown function

197 PBANKA_061490 conserved Plasmodium protein, unknown function yes

198 PBANKA_061630 conserved Plasmodium protein, unknown function

199 PBANKA_061730 conserved Plasmodium protein, unknown function

200 PBANKA_061740 conserved Plasmodium protein, unknown function

201 PBANKA_061860 conserved Plasmodium protein, unknown function

202 PBANKA_061890 conserved Plasmodium protein, unknown function

203 PBANKA_062120 conserved Plasmodium protein, unknown function

204 PBANKA_070180 conserved Plasmodium protein, unknown function yes

205 PBANKA_070460 conserved Plasmodium protein, unknown function

206 PBANKA_070570 conserved Plasmodium protein, unknown function yes 207 PBANKA_070660 conserved Plasmodium protein, unknown function

208 PBANKA_070980 conserved Plasmodium protein, unknown function

209 PBANKA_070990 conserved Plasmodium protein, unknown function yes

210 PBANKA_071040 conserved Plasmodium protein, unknown function

211 PBANKA_071180 conserved Plasmodium protein, unknown function yes

212 PBANKA_071280 conserved Plasmodium protein, unknown function

213 PBANKA_071410 conserved Plasmodium protein, unknown function yes

214 PBANKA_071820 conserved Plasmodium protein, unknown function

215 PBANKA_072160 conserved Plasmodium protein, unknown function yes

216 PBANKA_080090 conserved Plasmodium protein, unknown function yes

217 PBANKA_080130 conserved Plasmodium protein, unknown function

218 PBANKA_080200 conserved Plasmodium protein, unknown function yes

219 PBANKA_080240 conserved Plasmodium protein, unknown function yes

220 PBANKA_080360 conserved Plasmodium protein, unknown function

221 PBANKA_080390 conserved Plasmodium protein, unknown function yes

222 PBANKA_080420 conserved Plasmodium protein, unknown function yes

223 PBANKA_080480 conserved Plasmodium protein, unknown function yes

224 PBANKA_080610 conserved Plasmodium protein, unknown function

225 PBANKA_080730 conserved Plasmodium protein, unknown function

226 PBANKA_080810 conserved Plasmodium protein, unknown function yes

227 PBANKA_080850 conserved Plasmodium protein, unknown function yes

228 PBANKA_080950 conserved Plasmodium protein, unknown function yes

229 PBANKA_080960 conserved Plasmodium protein, unknown function yes

230 PBANKA_081250 conserved Plasmodium protein, unknown function yes

231 PBANKA_081310 conserved Plasmodium protein, unknown function

232 PBANKA_081320 conserved Plasmodium protein, unknown function

233 PBANKA_081410 conserved Plasmodium protein, unknown function yes

234 PBANKA_081430 conserved Plasmodium protein, unknown function

235 PBANKA_081470 conserved Plasmodium protein, unknown function

236 PBANKA_081720 conserved Plasmodium protein, unknown function

237 PBANKA_081750 conserved Plasmodium protein, unknown function

238 PBANKA_081760 conserved Plasmodium protein, unknown function yes

239 PBANKA_081790 conserved Plasmodium protein, unknown function yes

240 PBANKA_081830 conserved Plasmodium protein, unknown function

241 PBANKA_082500 conserved Plasmodium protein, unknown function 242 PBANKA_082510 conserved Plasmodium protein, unknown function

243 PBANKA_082670 conserved Plasmodium protein, unknown function

244 PBANKA_082700 conserved Plasmodium protein, unknown function

245 PBANKA_082920 conserved Plasmodium protein, unknown function yes

246 PBANKA_083080 conserved Plasmodium protein, unknown function

247 PBANKA_083210 conserved Plasmodium protein, unknown function yes

248 PBANKA_083220 conserved Plasmodium protein, unknown function yes

249 PBANKA_083290 conserved Plasmodium protein, unknown function yes

250 PBANKA_083590 conserved Plasmodium protein, unknown function yes

251 PBANKA_083620 conserved Plasmodium protein, unknown function yes

252 PBANKA_090180 conserved Plasmodium protein, unknown function yes

253 PBANKA_090290 conserved Plasmodium protein, unknown function yes

254 PBANKA_090630 conserved Plasmodium protein, unknown function yes

255 PBANKA_090800 conserved Plasmodium protein, unknown function

256 PBANKA_090860 conserved Plasmodium protein, unknown function

257 PBANKA_090970 conserved Plasmodium protein, unknown function

258 PBANKA_090980 conserved Plasmodium protein, unknown function

259 PBANKA_091140 conserved Plasmodium protein, unknown function

260 PBANKA_091190 conserved Plasmodium protein, unknown function yes

261 PBANKA_091200 conserved Plasmodium protein, unknown function yes

262 PBANKA_091220 conserved Plasmodium protein, unknown function yes

263 PBANKA_091240 conserved Plasmodium protein, unknown function yes

264 PBANKA_091350 conserved Plasmodium protein, unknown function

265 PBANKA_091400 conserved Plasmodium protein, unknown function yes

266 PBANKA_091420 conserved Plasmodium protein, unknown function

267 PBANKA_091480 conserved Plasmodium protein, unknown function

268 PBANKA_091510 conserved Plasmodium protein, unknown function yes

269 PBANKA_091520 conserved Plasmodium protein, unknown function yes

270 PBANKA_091600 conserved Plasmodium protein, unknown function

271 PBANKA_091770 conserved Plasmodium protein, unknown function yes

272 PBANKA_092140 conserved Plasmodium protein, unknown function yes

273 PBANKA_092190 conserved Plasmodium protein, unknown function

274 PBANKA_092450 conserved Plasmodium protein, unknown function

275 PBANKA_092560 conserved Plasmodium protein, unknown function

276 PBANKA_092610 conserved Plasmodium protein, unknown function 277 PBANKA_093510 conserved Plasmodium protein, unknown function yes

278 PBANKA_093590 conserved Plasmodium protein, unknown function

279 PBANKA_094070 conserved Plasmodium protein, unknown function yes

280 PBANKA_094210 conserved Plasmodium protein, unknown function yes

281 PBANKA_094250 conserved Plasmodium protein, unknown function

282 PBANKA_100090 conserved Plasmodium protein, unknown function

283 PBANKA_100100 conserved Plasmodium protein, unknown function

284 PBANKA_100130 conserved Plasmodium protein, unknown function

285 PBANKA_100190 conserved Plasmodium protein, unknown function

286 PBANKA_100520 conserved Plasmodium protein, unknown function yes

287 PBANKA_100600 conserved Plasmodium protein, unknown function

288 PBANKA_100660 conserved Plasmodium protein, unknown function

289 PBANKA_100690 conserved Plasmodium protein, unknown function yes

290 PBANKA_100710 conserved Plasmodium protein, unknown function yes

291 PBANKA_100840 conserved Plasmodium protein, unknown function yes

292 PBANKA_101000 conserved Plasmodium protein, unknown function

293 PBANKA_101040 conserved Plasmodium protein, unknown function yes

294 PBANKA_101430 conserved Plasmodium protein, unknown function

295 PBANKA_101930 conserved Plasmodium protein, unknown function

296 PBANKA_101970 conserved Plasmodium protein, unknown function

297 PBANKA_102160 conserved Plasmodium protein, unknown function

298 PBANKA_102420 conserved Plasmodium protein, unknown function

299 PBANKA_102450 conserved Plasmodium protein, unknown function

300 PBANKA_103050 conserved Plasmodium protein, unknown function

301 PBANKA_103070 conserved Plasmodium protein, unknown function

302 PBANKA_103080 conserved Plasmodium protein, unknown function yes

303 PBANKA_103200 conserved Plasmodium protein, unknown function

304 PBANKA_103290 conserved Plasmodium protein, unknown function yes

305 PBANKA_103350 conserved Plasmodium protein, unknown function yes

306 PBANKA_103400 conserved Plasmodium protein, unknown function yes

307 PBANKA_103740 conserved Plasmodium protein, unknown function yes

308 PBANKA_103810 conserved Plasmodium protein, unknown function yes

309 PBANKA_103980 conserved Plasmodium protein, unknown function

310 PBANKA_103990 conserved Plasmodium protein, unknown function

311 PBANKA_110200 conserved Plasmodium protein, unknown function yes 312 PBANKA_110350 conserved Plasmodium protein, unknown function

313 PBANKA_110430 conserved Plasmodium protein, unknown function

314 PBANKA_110500 conserved Plasmodium protein, unknown function

315 PBANKA_110660 conserved Plasmodium protein, unknown function

316 PBANKA_110910 conserved Plasmodium protein, unknown function

317 PBANKA_110950 conserved Plasmodium protein, unknown function

318 PBANKA_111080 conserved Plasmodium protein, unknown function yes

319 PBANKA_111360 conserved Plasmodium protein, unknown function yes

320 PBANKA_111680 conserved Plasmodium protein, unknown function yes

321 PBANKA_111720 conserved Plasmodium protein, unknown function yes

322 PBANKA_111880 conserved Plasmodium protein, unknown function

323 PBANKA_112050 conserved Plasmodium protein, unknown function

324 PBANKA_112120 conserved Plasmodium protein, unknown function

325 PBANKA_112730 conserved Plasmodium protein, unknown function

326 PBANKA_112760 conserved Plasmodium protein, unknown function

327 PBANKA_112840 conserved Plasmodium protein, unknown function

328 PBANKA_113030 conserved Plasmodium protein, unknown function yes

329 PBANKA_113220 conserved Plasmodium protein, unknown function yes

330 PBANKA_113370 conserved Plasmodium protein, unknown function yes

331 PBANKA_113390 conserved Plasmodium protein, unknown function

332 PBANKA_113500 conserved Plasmodium protein, unknown function

333 PBANKA_113530 conserved Plasmodium protein, unknown function

334 PBANKA_113780 conserved Plasmodium protein, unknown function

335 PBANKA_113870 conserved Plasmodium protein, unknown function

336 PBANKA_114180 conserved Plasmodium protein, unknown function yes

337 PBANKA_114440 conserved Plasmodium protein, unknown function yes

338 PBANKA_114550 conserved Plasmodium protein, unknown function yes

339 PBANKA_114560 conserved Plasmodium protein, unknown function

340 PBANKA_120100 conserved Plasmodium protein, unknown function

341 PBANKA_120290 conserved Plasmodium protein, unknown function

342 PBANKA_120300 conserved Plasmodium protein, unknown function

343 PBANKA_120320 conserved Plasmodium protein, unknown function

344 PBANKA_120400 conserved Plasmodium protein, unknown function

345 PBANKA_120760 conserved Plasmodium protein, unknown function yes

346 PBANKA_120950 conserved Plasmodium protein, unknown function 347 PBANKA_121050 conserved Plasmodium protein, unknown function yes

348 PBANKA_121210 conserved Plasmodium protein, unknown function yes

349 PBANKA_121220 conserved Plasmodium protein, unknown function

350 PBANKA_121390 conserved Plasmodium protein, unknown function

351 PBANKA_121740 conserved Plasmodium protein, unknown function yes

352 PBANKA_122080 conserved Plasmodium protein, unknown function yes

353 PBANKA_122100 conserved Plasmodium protein, unknown function

354 PBANKA_122300 conserved Plasmodium protein, unknown function

355 PBANKA_122390 conserved Plasmodium protein, unknown function

356 PBANKA_122460 conserved Plasmodium protein, unknown function

357 PBANKA_122780 conserved Plasmodium protein, unknown function

358 PBANKA_122790 conserved Plasmodium protein, unknown function

359 PBANKA_123070 conserved Plasmodium protein, unknown function yes

360 PBANKA_123090 conserved Plasmodium protein, unknown function

361 PBANKA_123380 conserved Plasmodium protein, unknown function

362 PBANKA_123550 conserved Plasmodium protein, unknown function yes

363 PBANKA_123600 conserved Plasmodium protein, unknown function

364 PBANKA_123970 conserved Plasmodium protein, unknown function yes

365 PBANKA_124050 conserved Plasmodium protein, unknown function

366 PBANKA_124150 conserved Plasmodium protein, unknown function yes

367 PBANKA_124370 conserved Plasmodium protein, unknown function

368 PBANKA_124580 conserved Plasmodium protein, unknown function

369 PBANKA_130060 conserved Plasmodium protein, unknown function

370 PBANKA_130110 conserved Plasmodium protein, unknown function yes

371 PBANKA_130160 conserved Plasmodium protein, unknown function yes

372 PBANKA_130320 conserved Plasmodium protein, unknown function

373 PBANKA_130480 conserved Plasmodium protein, unknown function

374 PBANKA_130560 conserved Plasmodium protein, unknown function yes

375 PBANKA_130730 conserved Plasmodium protein, unknown function

376 PBANKA_130950 conserved Plasmodium protein, unknown function

377 PBANKA_131120 conserved Plasmodium protein, unknown function yes

378 PBANKA_131450 conserved Plasmodium protein, unknown function yes

379 PBANKA_131520 conserved Plasmodium protein, unknown function yes

380 PBANKA_131670 conserved Plasmodium protein, unknown function yes

381 PBANKA_131960 conserved Plasmodium protein, unknown function 382 PBANKA_132000 conserved Plasmodium protein, unknown function yes

383 PBANKA_132210 conserved Plasmodium protein, unknown function yes

384 PBANKA_132250 conserved Plasmodium protein, unknown function yes

385 PBANKA_132300 conserved Plasmodium protein, unknown function yes

386 PBANKA_132310 conserved Plasmodium protein, unknown function yes

387 PBANKA_132420 conserved Plasmodium protein, unknown function yes

388 PBANKA_132450 conserved Plasmodium protein, unknown function

389 PBANKA_132740 conserved Plasmodium protein, unknown function yes

390 PBANKA_132750 conserved Plasmodium protein, unknown function yes

391 PBANKA_132860 conserved Plasmodium protein, unknown function

392 PBANKA_133050 conserved Plasmodium protein, unknown function yes

393 PBANKA_133150 conserved Plasmodium protein, unknown function yes

394 PBANKA_133260 conserved Plasmodium protein, unknown function

395 PBANKA_133290 conserved Plasmodium protein, unknown function yes

396 PBANKA_133400 conserved Plasmodium protein, unknown function

397 PBANKA_133600 conserved Plasmodium protein, unknown function

398 PBANKA_133880 conserved Plasmodium protein, unknown function yes

399 PBANKA_133910 conserved Plasmodium protein, unknown function

400 PBANKA_134090 conserved Plasmodium protein, unknown function yes

401 PBANKA_134450 conserved Plasmodium protein, unknown function

402 PBANKA_134520 conserved Plasmodium protein, unknown function yes

403 PBANKA_134580 conserved Plasmodium protein, unknown function yes

404 PBANKA_134990 conserved Plasmodium protein, unknown function

405 PBANKA_135160 conserved Plasmodium protein, unknown function

406 PBANKA_135300 conserved Plasmodium protein, unknown function yes

407 PBANKA_135370 conserved Plasmodium protein, unknown function yes

408 PBANKA_135740 conserved Plasmodium protein, unknown function

409 PBANKA_135760 conserved Plasmodium protein, unknown function yes

410 PBANKA_135940 conserved Plasmodium protein, unknown function yes

411 PBANKA_135990 conserved Plasmodium protein, unknown function

412 PBANKA_136170 conserved Plasmodium protein, unknown function yes

413 PBANKA_136330 conserved Plasmodium protein, unknown function yes

414 PBANKA_136530 conserved Plasmodium protein, unknown function yes

415 PBANKA_140140 conserved Plasmodium protein, unknown function

416 PBANKA_140180 conserved Plasmodium protein, unknown function yes 417 PBANKA_140190 conserved Plasmodium protein, unknown function yes

418 PBANKA_140280 conserved Plasmodium protein, unknown function

419 PBANKA_140310 conserved Plasmodium protein, unknown function

420 PBANKA_140390 conserved Plasmodium protein, unknown function

421 PBANKA_140450 conserved Plasmodium protein, unknown function yes

422 PBANKA_140830 conserved Plasmodium protein, unknown function

423 PBANKA_140860 conserved Plasmodium protein, unknown function yes

424 PBANKA_140890 conserved Plasmodium protein, unknown function

425 PBANKA_140930 conserved Plasmodium protein, unknown function

426 PBANKA_140970 conserved Plasmodium protein, unknown function

427 PBANKA_141070 conserved Plasmodium protein, unknown function

428 PBANKA_141150 conserved Plasmodium protein, unknown function yes

429 PBANKA_141190 conserved Plasmodium protein, unknown function

430 PBANKA_141230 conserved Plasmodium protein, unknown function

431 PBANKA_141250 conserved Plasmodium protein, unknown function

432 PBANKA_141370 conserved Plasmodium protein, unknown function yes

433 PBANKA_141580 conserved Plasmodium protein, unknown function

434 PBANKA_141590 conserved Plasmodium protein, unknown function

435 PBANKA_141610 conserved Plasmodium protein, unknown function

436 PBANKA_141750 conserved Plasmodium protein, unknown function

437 PBANKA_142300 conserved Plasmodium protein, unknown function yes

438 PBANKA_142340 conserved Plasmodium protein, unknown function

439 PBANKA_142400 conserved Plasmodium protein, unknown function

440 PBANKA_142420 conserved Plasmodium protein, unknown function yes

441 PBANKA_142540 conserved Plasmodium protein, unknown function yes

442 PBANKA_142550 conserved Plasmodium protein, unknown function yes

443 PBANKA_142630 conserved Plasmodium protein, unknown function

444 PBANKA_142790 conserved Plasmodium protein, unknown function

445 PBANKA_142840 conserved Plasmodium protein, unknown function

446 PBANKA_143050 conserved Plasmodium protein, unknown function

447 PBANKA_143680 conserved Plasmodium protein, unknown function

448 PBANKA_143690 conserved Plasmodium protein, unknown function yes

449 PBANKA_143700 conserved Plasmodium protein, unknown function

450 PBANKA_144030 conserved Plasmodium protein, unknown function yes

451 PBANKA_144050 conserved Plasmodium protein, unknown function 452 PBANKA_144150 conserved Plasmodium protein, unknown function yes

453 PBANKA_144170 conserved Plasmodium protein, unknown function

454 PBANKA_144240 conserved Plasmodium protein, unknown function

455 PBANKA_144290 conserved Plasmodium protein, unknown function

456 PBANKA_144310 conserved Plasmodium protein, unknown function

457 PBANKA_144340 conserved Plasmodium protein, unknown function

458 PBANKA_144470 conserved Plasmodium protein, unknown function

459 PBANKA_144520 conserved Plasmodium protein, unknown function yes

460 PBANKA_144550 conserved Plasmodium protein, unknown function yes

461 PBANKA_144810 conserved Plasmodium protein, unknown function yes

462 PBANKA_144920 conserved Plasmodium protein, unknown function

463 PBANKA_145470 conserved Plasmodium protein, unknown function yes

464 PBANKA_145530 conserved Plasmodium protein, unknown function

465 PBANKA_145660 conserved Plasmodium protein, unknown function

466 PBANKA_145710 conserved Plasmodium protein, unknown function

467 PBANKA_145760 conserved Plasmodium protein, unknown function yes

468 PBANKA_145810 conserved Plasmodium protein, unknown function yes

469 PBANKA_145900 conserved Plasmodium protein, unknown function

470 PBANKA_146010 conserved Plasmodium protein, unknown function

471 PBANKA_146260 conserved Plasmodium protein, unknown function

472 PBANKA_146360 conserved Plasmodium protein, unknown function yes

473 PBANKA_146380 conserved Plasmodium protein, unknown function yes

conserved Plasmodium protein, unknown function 474 PBANKA_093270 (PCAS_091160:exon:5)

475 PBANKA_120630 conserved Plasmodium protein, unknown function (UIS11) yes

476 PBANKA_050620 conserved Plasmodium protein, unknown function (UIS12)

477 PBANKA_143600 conserved Plasmodium protein, unknown function (UIS27) yes

478 PBANKA_146430 conserved Plasmodium protein, unknown function, fragment

479 PBANKA_146440 conserved Plasmodium protein, unknown function, fragment

480 PBANKA_031060 conserved protein, unknown function

481 PBANKA_070160 conserved protein, unknown function

482 PBANKA_130100 conserved protein, unknown function

483 PBANKA_141950 conserved protein, unknown function yes

484 PBANKA_052450 conserved rodent malaria protein, unknown function yes

485 PBANKA_130290 copper transporter, putative yes 486 PBANKA_146240 cutA, putative

487 PBANKA_121660 cyclic amine resistance locus protein, putative (CARL)

488 PBANKA_140320 cyclin, putative yes

489 PBANKA_061430 cysteine desulfurase, putative (SufS)

490 PBANKA_132170 cysteine proteinase, putative yes

491 PBANKA_081240 cysteine repeat modular protein 1 (CRMP1) yes

492 PBANKA_130080 cysteine repeat modular protein 4 (CRMP4) yes

493 PBANKA_103260 cytidine diphosphate-diacylglycerol synthase, putative (CDS)

494 PBANKA_140060 cytoadherence linked asexual protein, putative yes

495 PBANKA_143950 cytochrome c heme lyase, putative yes

496 PBANKA_103800 cytochrome c, putative

497 PBANKA_060260 cytochrome c1 heme lyase, putative yes

498 PBANKA_141020 cytochrome c2 precursor,putative yes

499 PBANKA_101350 cytosolic preribosomal GTPase, putative yes

500 PBANKA_133970 DEAD box helicase, putative

501 PBANKA_140580 DEAD box helicase, putative

502 PBANKA_141180 DEAD box helicase, putative

503 PBANKA_112970 DEAD/DEAH box ATP-dependent RNA helicase, putative yes

504 PBANKA_130300 DEAD/DEAH helicase, putative yes

505 PBANKA_145520 DEAD/DEAH helicase, putative

506 PBANKA_145920 delta-aminolevulinic acid synthetase, putative

507 PBANKA_140110 deoxyhypusine hydroxylase, putative yes

508 PBANKA_103000 deoxyhypusine synthase, putative yes

509 PBANKA_041200 DER1-like protein, putative yes

510 PBANKA_133460 diacylglycerol kinase, putative

511 PBANKA_134000 dihydrofolate synthase/folylpolyglutamate synthase, putative yes

512 PBANKA_050500 dihydrolipoamide acyltransferase, putative yes

513 PBANKA_144690 dihydrolipoamide dehydrogenase, putative (mLipDH) yes

514 PBANKA_133610 dihydroorotase, putative

515 PBANKA_142670 dihydropteroate synthetase, putative

516 PBANKA_102890 diphthamide synthesis protein, putative yes

517 PBANKA_120730 diphthine synthase, putative yes

518 PBANKA_021140 DNA (cytosine-5)-methyltransferase, putative (DNMT2)

519 PBANKA_101710 DNA mismatch repair protein, putative

520 PBANKA_112420 DNA polymerase 1, putative yes 521 PBANKA_052050 DNA repair helicase rad25, putative

522 PBANKA_130190 DNA repair metallo-beta-lactamase protein, putative

523 PBANKA_121010 DNA repair protein RAD23, putative

524 PBANKA_103110 DNA replication enzyme, putative (PREX)

525 PBANKA_071830 DNA replication licensing factor, putative yes

526 PBANKA_094020 dna2/nam7 helicase family member, putative yes

527 PBANKA_133040 DNA-3-methyladenine glycosylase, putative yes

528 PBANKA_143250 DNA-binding chaperone, putative

529 PBANKA_103320 DNA-damage inducible protein, putative

530 PBANKA_091380 DNA-directed RNA polymerase 1, subunit 2, putative

531 PBANKA_082390 DNA-directed RNA polymerase II, putative yes

532 PBANKA_060520 DNA-directed RNA polymerase III subunit, putative

533 PBANKA_133590 DNA-directed RNA polymerase, alpha subunit, putative yes

534 PBANKA_102880 DnaJ protein, putative

535 PBANKA_110250 DnaJ protein, putative

536 PBANKA_140570 DnaJ protein, putative

dolichyl-diphosphooligosaccharide--protein- 537 PBANKA_082050 yes glycosyltransferase, putative

538 PBANKA_093870 D-tyrosyl-tRNA(Tyr) deacylase, putative (DTD)

539 PBANKA_133270 duffy-binding protein yes

540 PBANKA_140080 early transcribed membrane protein 13 (UIS3) yes

541 PBANKA_091230 EBNA2 binding protein P100 homologue, putative

542 PBANKA_112220 EGF-like membrane protein, putative yes

543 PBANKA_040280 EH (Eps15 homology) protein, putative yes

544 PBANKA_040350 elongation factor (EF-TS), putative (EF-Ts)

545 PBANKA_135200 elongation factor 1-gamma, putative yes

546 PBANKA_131480 elongation factor 2, putative yes

547 PBANKA_010120 elongation factor G, putative (EF-G)

548 PBANKA_050560 endomembrane protein 70, putative

549 PBANKA_135080 endopeptidase, putative

550 PBANKA_143730 endoplasmin homolog precursor, putative yes

551 PBANKA_052060 enhancer of rudimentary homolog, putative yes

552 PBANKA_136050 ethanolamine-phosphate cytidylyltransferase (ECT) yes

553 PBANKA_061080 eukaryotic initiation factor 2a, putative yes

554 PBANKA_120610 eukaryotic translation initiation factor 3 subunit 7, putative yes 555 PBANKA_060480 eukaryotic translation initiation factor 3 subunit 8, putative

556 PBANKA_060320 eukaryotic translation initiation factor 5a, putative (EIF5A) yes

557 PBANKA_050320 eukaryotic translation initiation factor subunit eIF2A, putative

558 PBANKA_061450 eukaryotic translation initiation factor subunit, putative yes

559 PBANKA_070650 exonuclease, putative

560 PBANKA_100780 exosome complex component RRP4, putative (RRP4) yes

561 PBANKA_135350 exosome complex component RRP42, putative (RRP42)

562 PBANKA_101680 exosome complex exonuclease rrp41, putative

563 PBANKA_114040 exosome complex exonuclease, putative

564 PBANKA_133430 exported protein 2, putative (EXP2) yes

565 PBANKA_090160 farnesyltransferase beta subunit, putative yes

566 PBANKA_131930 ferlin, putative yes

567 PBANKA_141660 ferredoxin, putative yes

568 PBANKA_114070 ferrochelatase, putative

FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, 569 PBANKA_146040 putative (FKBP35)

570 PBANKA_140630 fork head domain protein, putative

571 PBANKA_041440 formate-nitrite transporter, putative

572 PBANKA_123750 G10 protein, putative yes

573 PBANKA_052100 GDP dissociation inhibitor, putative

574 PBANKA_030860 GDP-fructose:GMP antiporter, putative

575 PBANKA_091980 geranylgeranyl pyrophosphate synthase, putative (GGPPS) yes

576 PBANKA_010130 geranylgeranyltransferase, putative

577 PBANKA_145730 glucose inhibited division protein a homologue, putative yes

578 PBANKA_113350 glutamate - tRNA ligase, putative yes

579 PBANKA_071810 glutamyl-tRNA(Gln) amidotransferase subunit A, putative yes

580 PBANKA_111180 glutathione synthetase (GS) yes

581 PBANKA_142850 glycerol-3-phosphate acyltransferase, putative yes

582 PBANKA_143190 glycerol-3-phosphate dehydrogenase, putative

583 PBANKA_051460 glycoprotease, putative

glycyl-tRNA synthetase, putative,glycine--tRNA ligase, putative 584 PBANKA_102280 (GlyRS)

585 PBANKA_093390 glyoxalase I, putative yes

586 PBANKA_070190 GPI-anchored micronemal antigen, putative (GAMA) yes

587 PBANKA_093340 GTPase activating protein, putative yes 588 PBANKA_100810 GTPase, putative

589 PBANKA_102040 GTPase, putative

590 PBANKA_081280 GTP-binding protein, putative

591 PBANKA_103090 GTP-binding protein, putative

592 PBANKA_130610 GTP-binding protein, putative

593 PBANKA_130680 guanine nucleotide exchange factor, putative

594 PBANKA_093120 heat shock protein 101, putative

595 PBANKA_121400 heat shock protein 60, putative yes

596 PBANKA_121930 heat shock protein 70, putative (HSP70-z) yes

597 PBANKA_121900 heat shock protein 90, putative

598 PBANKA_130780 heat shock protein 90, putative

599 PBANKA_091440 heat shock protein hsp70 homologue, putative (UIS24)

600 PBANKA_081110 helicase, putative yes

601 PBANKA_143610 heterochromatin protein 1, putative (HP1) yes

602 PBANKA_112290 hexokinase, putative

603 PBANKA_130890 histidine -- tRNA ligase, putative yes

604 PBANKA_070730 histone acetyltransferase GCN5, putative (GCN5) yes

605 PBANKA_144250 histone acetyltransferase, putative

606 PBANKA_142600 histone-arginine methyltransferase, putative (CARM1) yes

607 PBANKA_143000 histone-lysine N-methyltransferase, putative

608 PBANKA_052160 holo-(acyl-carrier protein) synthase, putative yes

609 PBANKA_144830 homocysteine S-methyltransferase, putative

610 PBANKA_061090 HSP40, subfamily A, putative yes

611 PBANKA_101050 Hsp70/Hsp90 organizing protein, putative (HOP)

hypoxanthine-guanine phosphoribosyltransferase, putative 612 PBANKA_121080 (HGPRT)

613 PBANKA_113970 indole-3-glycerol-phosphate synthase, putative

614 PBANKA_082170 inosine-5'-monophosphate dehydrogenase, putative

615 PBANKA_122770 inositol phosphatase, putative

616 PBANKA_092980 insulinase, putative

617 PBANKA_094350 iron-sulfur assembly protein, sufD, putative

618 PBANKA_061380 large ribosomal subunit assembling factor, putative yes

619 PBANKA_132140 large ribosomal subunit nuclear export factor, putative (UIS20) yes

620 PBANKA_142410 large ribosomal subunit processing factor, putative

621 PBANKA_130990 leucine aminopeptidase, putative yes 622 PBANKA_130360 leucine carboxyl methyltransferase, putative yes

623 PBANKA_146250 leucine-rich repeat protein (LRR12)

624 PBANKA_131580 leucine-rich repeat protein (LRR3)

625 PBANKA_020590 lipid/sterol:H symporter, putative

626 PBANKA_071490 lipoamide dehydrogenase, putative

627 PBANKA_070700 lipoate-protein ligase (LipB)

628 PBANKA_135750 lipoyl synthase (LipA)

629 PBANKA_102460 liver specific protein 1 (LISP1) yes

630 PBANKA_082090 long chain fatty acid elongation enzyme, putative

631 PBANKA_031180 long-chain acyl-CoA synthase, putative yes

632 PBANKA_136290 lysine -- tRNA ligase, putative

633 PBANKA_020130 lysophospholipase, putative yes

634 PBANKA_122020 lysophospholipase, putative yes

635 PBANKA_141030 M1-family aminopeptidase, putative

636 PBANKA_144400 macrophage migration inhibitory factor (MIF) yes

637 PBANKA_130470 major facilitator superfamily, putative

malonyl CoA-acyl carrier protein transacylase precursor, 638 PBANKA_141050 yes putative

639 PBANKA_122840 mannose-6-phosphate isomerase, putative

640 PBANKA_130120 mediator complex subunit 31, putative

641 PBANKA_140410 membrane integral peptidase, M50 family, putative

642 PBANKA_071960 memo-like protein yes

643 PBANKA_083100 merozoite surface protein 1 (MSP1) yes

644 PBANKA_134910 merozoite surface protein 7 (MSP7) yes

645 PBANKA_110220 merozoite surface protein 8 (MSP8)

646 PBANKA_144330 merozoite surface protein 9, putative

647 PBANKA_122620 methionine aminopeptidase, putative

648 PBANKA_101020 methionine aminopeptidase, type II, putative yes

649 PBANKA_080190 methyltransferase, putative

650 PBANKA_082600 methyltransferase, putative yes

651 PBANKA_141870 microsomal signal peptidase, putative

652 PBANKA_100510 mitochondrial carrier protein, putative

653 PBANKA_114460 mitochondrial carrier protein, putative

654 PBANKA_142640 mitochondrial carrier protein, putative

655 PBANKA_143870 mitochondrial carrier protein, putative 656 PBANKA_113250 mitochondrial inner membrane translocase, putative yes

mitochondrial preribosomal assembly protein rimM precursor, 657 PBANKA_051580 putative

658 PBANKA_102180 mitochondrial protein import protein TIM13, putative yes

659 PBANKA_102130 mitochondrial ribosomal protein L21 precursor, putative

660 PBANKA_010380 mitochondrial ribosomal protein L24 precursor, putative

661 PBANKA_041390 mitochondrial ribosomal protein L27 precursor, putative yes

662 PBANKA_132030 mitochondrial ribosomal protein L28 precursor, putative

663 PBANKA_112570 mitochondrial ribosomal protein L46 precursor, putative

664 PBANKA_131830 mitochondrial ribosomal protein S11 precursor, putative

665 PBANKA_061340 mitochondrial ribosomal protein S12 precursor, putative

666 PBANKA_140940 mitochondrial ribosomal protein S15 precursor, putative

667 PBANKA_130910 mitochondrial ribosomal protein S29 precursor, putative

668 PBANKA_141080 mitochondrial ribosomal protein S35 precursor, putative

669 PBANKA_113560 mitotic control protein dis3 homologue, putative (RRP44)

670 PBANKA_121280 MO15-related protein kinase (MRK)

671 PBANKA_082720 monocarboxylase transporter, putative yes

672 PBANKA_020440 mRNA cleavage factor-like protein, putative

673 PBANKA_134900 MSP7-like protein (MSRP2) yes

674 PBANKA_144380 multidrug resistance-associated protein 1 (MRP)

675 PBANKA_010100 MYND finger protein, putative

676 PBANKA_111140 myo-inositol 1-phosphate synthase, putative yes

677 PBANKA_011220 myosin-like protein, putative yes

678 PBANKA_112360 N-acetylglucosaminylphosphatidylinositol deacetylase, putative yes

679 PBANKA_082750 NAD synthase, putative

680 PBANKA_102620 NADP-specific glutamate dehydrogenase, putative (GDH1) yes

681 PBANKA_101400 NADP-specific glutamate dehydrogenase, putative (GDH2) yes

682 PBANKA_040160 N-ethylmaleimide-sensitive fusion protein, putative

683 PBANKA_092420 neutral-sphingomyelinase activation factor protein, putative

684 PBANKA_112770 nicotinate phosphoribosyltransferase, putative

685 PBANKA_134280 nicotinic acid mononucleotide adenyltransferase yes

686 PBANKA_020830 novel putative transporter 1 (NPT1) yes

687 PBANKA_103030 nuclear transport factor 2, putative yes

688 PBANKA_030150 nucleolar preribosomal assembly protein, putative

689 PBANKA_071480 nucleolar preribosomal assembly protein, putative yes nucleolar preribosomal associated cytoplasmic ATPase, 690 PBANKA_136260 yes putative

691 PBANKA_146080 nucleolar rRNA processing protein, putative

692 PBANKA_136190 nucleoside diphosphate hydrolase, putative

693 PBANKA_136010 nucleoside transporter 1 (NT1) yes

694 PBANKA_020990 nucleoside transporter, putative yes

695 PBANKA_070620 nucleoside transporter, putative (NT2)

696 PBANKA_093140 oligosaccharyl transferase STT3 subunit, putative

697 PBANKA_121810 oocyst capsule protein (Cap380) yes

698 PBANKA_011250 organic anion transporter, putative

699 PBANKA_103340 oxidoreductase, putative yes

700 PBANKA_040850 parasite-infected erythrocyte surface protein (PIESP1)

701 PBANKA_100650 peptidase, M22 family, putative yes

702 PBANKA_121700 peptidase, putative

703 PBANKA_080930 peptide deformylase, putative

704 PBANKA_124330 peptidyl-prolyl cis-trans isomerase, putative (CYP23)

705 PBANKA_143100 peptidyl-prolyl cis-trans isomerase, putative (CYP32)

706 PBANKA_083130 peptidyl-prolyl cis-trans isomerase, putative (CYP72)

707 PBANKA_110980 peptidyl-prolyl cis-trans isomerase, putative (CYP87)

708 PBANKA_094290 phenylalanyl-tRNA synthetase beta chain, putative yes

709 PBANKA_050270 PHF5-like protein, putative

710 PBANKA_121110 phosphatase, putative yes

711 PBANKA_082870 phosphatidylserine decarboxylase, putative yes

712 PBANKA_141990 phosphodiesterase gamma (PDEgamma) yes

713 PBANKA_030620 phospholipase A2, putative yes

714 PBANKA_071470 phosphopantothenoylcysteine decarboxylase, putative yes

715 PBANKA_061360 phosphopantothenoylcysteine synthetase, putative

716 PBANKA_010070 Plasmodium exported protein, unknown function

717 PBANKA_011260 Plasmodium exported protein, unknown function

718 PBANKA_020150 Plasmodium exported protein, unknown function yes

719 PBANKA_031630 Plasmodium exported protein, unknown function yes

720 PBANKA_114540 Plasmodium exported protein, unknown function yes

721 PBANKA_120060 Plasmodium exported protein, unknown function yes

722 PBANKA_122900 Plasmodium exported protein, unknown function yes

723 PBANKA_021460 Plasmodium exported protein, unknown function, fragment yes 724 PBANKA_041850 Plasmodium exported protein, unknown function, fragment

725 PBANKA_010520 polypyrimidine tract binding protein, putative yes

726 PBANKA_144200 potassium channel, putative (Kch1)

727 PBANKA_011090 PP-loop family protein, putative yes

728 PBANKA_093940 prefoldin, putative

729 PBANKA_040910 pre-mRNA splicing factor, putative yes

730 PBANKA_143530 pre-mRNA splicing factor, putative yes

731 PBANKA_100310 pre-mRNA-processing-splicing factor 8, putative (PRPF8)

pre-mRNA-splicing factor ATP-dependent RNA helicase 732 PBANKA_081860 yes PRP43, putative (PRP43)

733 PBANKA_010860 Pre-mRNA-splicing factor SLU7, putative (SLU7) yes

734 PBANKA_092960 pre-RNA processing ribonucleoprotein, putative

735 PBANKA_101630 proliferation-associated protein 2g4, putative yes

736 PBANKA_082610 prolyl-t-RNA synthase, putative

737 PBANKA_081450 protease, putative

738 PBANKA_122650 proteasome beta-subunit, putative

739 PBANKA_083260 proteasome precursor, putative

740 PBANKA_080740 proteasome regulatory protein, putative

741 PBANKA_123310 proteasome subunit beta type 1, putative yes

742 PBANKA_091430 protein disulfide isomerase related protein, putative

743 PBANKA_092660 protein GCN20, putative yes

744 PBANKA_135090 protein kinase 6 (PK6)

745 PBANKA_112690 protein kinase PK4 (PK4)

746 PBANKA_082690 protein kinase, putative

747 PBANKA_090110 protein kinase, putative yes

748 PBANKA_122880 protein kinase, putative yes

749 PBANKA_144560 protein kinase, putative yes

750 PBANKA_112270 protein kinase, putative (TKL4)

751 PBANKA_120790 protein phosphatase, putative

752 PBANKA_070800 protein transport protein Sec23, putative (SEC23) yes

753 PBANKA_134650 protein tyrosine phosphatase, putative

754 PBANKA_145140 protein-S-isoprenylcysteine O-methyltransferase, putative

755 PBANKA_102520 pseudouridine synthase, putative

756 PBANKA_081500 pseudouridylate synthase, putative

757 PBANKA_122600 pseudouridylate synthase, putative yes 758 PBANKA_082060 pyridoxal 5'-phosphate dependent enzyme class III, putative

759 PBANKA_113420 pyrroline carboxylate reductase, putative yes

760 PBANKA_131010 pyruvate dehydrogenase E1 beta subunit, putative yes

pyruvate dehydrogenase E1 component, alpha subunit, 761 PBANKA_092380 yes putative

762 PBANKA_052000 pyruvate kinase 2, putative yes

763 PBANKA_061510 queuine tRNA-ribosyltransferase, putative yes

764 PBANKA_140910 Rab5b, GTPase, putative yes

765 PBANKA_103530 radical SAM protein, putative yes

766 PBANKA_112110 radical SAM protein, putative

767 PBANKA_051380 RAP protein, putative yes

768 PBANKA_112790 RAP protein, putative

769 PBANKA_131730 RAP protein, putative

770 PBANKA_133380 RAP protein, putative

771 PBANKA_140530 RED-like protein, putative

772 PBANKA_072070 regulator of chromosome condensation, putative yes

773 PBANKA_082080 regulator of chromosome condensation, putative

774 PBANKA_091330 regulator of chromosome condensation, putative

775 PBANKA_121510 Rh5 interacting protein, putative (RIPR) yes

776 PBANKA_135810 rhomboid protease ROM6, putative

777 PBANKA_041600 RhopH3, putative yes

778 PBANKA_080450 rhoptry associated membrane antigen, putative (RAMA)

779 PBANKA_146490 rhoptry neck protein 3, putative (RON3) yes

780 PBANKA_071310 rhoptry neck protein 5, putative (RON5) yes

781 PBANKA_031170 rhoptry neck protein 6, putative (RON6) yes

782 PBANKA_141830 rhoptry protein 2, putative (PRP2)

783 PBANKA_010040 rhoptry protein, putative yes

784 PBANKA_083020 rhoptry protein-2, putative

rhoptry-associated leucine zipper-like protein 1, putative 785 PBANKA_061970 (RALP1)

786 PBANKA_103210 rhoptry-associated protein 1, putative (RAP1) yes

787 PBANKA_123610 ribosomal large subunit pseudouridylate synthase, putative

788 PBANKA_080920 ribosomal protein L35, putative

789 PBANKA_080400 ribosomal protein, L37e, putative yes

790 PBANKA_140810 ribosomal RNA methyltransferase, putative 791 PBANKA_131560 ribosome biogenesis protein tsr1, putative

792 PBANKA_052180 ribosome recycling factor, putative yes

793 PBANKA_133420 RNA 3'-terminal phosphate cyclase-like protein, putative

794 PBANKA_130900 RNA helicase, putative yes

795 PBANKA_135400 RNA lariat debranching enzyme, putative (DBR1)

796 PBANKA_051470 RNA methyltransferase, putative

797 PBANKA_091880 RNA methyltransferase, putative yes

798 PBANKA_110900 RNA polymerase I, putative yes

799 PBANKA_070870 RNA polymerase II mediator complex protein MED7, putative

800 PBANKA_094220 RNA polymerase subunit, putative yes

801 PBANKA_102190 RNA polymerase subunit, putative yes

802 PBANKA_144320 RNA pseudouridylate synthase, putative

803 PBANKA_121640 RNA triphosphatase, putative

804 PBANKA_102740 RNA-binding protein, putative

805 PBANKA_131770 RNA-binding protein, putative

806 PBANKA_142500 RNA-binding protein, putative

807 PBANKA_114410 RNAse L inhibitor protein, putative

808 PBANKA_094090 RuvB DNA helicase, putative yes

S-adenosyl-L-methionine-dependent methyltransferase, 809 PBANKA_050460 putative

810 PBANKA_051690 S-adenosylmethionine decarboxylase, putative

811 PBANKA_145130 s-adenosyl-methyltransferase, putative

812 PBANKA_140480 SAM dependent methyltransferase, putative yes

secreted protein with altered thrombospondin repeat domain, 813 PBANKA_030950 putative (SPATR)

814 PBANKA_134710 sedlin, putative

815 PBANKA_041080 SEL-1 like protein yes

816 PBANKA_081160 selenophosphate synthetase, putative

817 PBANKA_141210 septum formation protein MAF homologue, putative yes

818 PBANKA_100300 sequestrin, putative yes

819 PBANKA_030510 serine repeat antigen 1 (SERA1) yes

820 PBANKA_030500 serine repeat antigen 2 (SERA2) yes

821 PBANKA_030490 serine repeat antigen 3 (SERA3) yes

822 PBANKA_030480 serine repeat antigen 4 (SERA4)

823 PBANKA_080220 serine/threonine protein kinase, putative 824 PBANKA_052320 serpentine receptor, putative (SR12)

825 PBANKA_061540 seryl-tRNA synthetase, putative

826 PBANKA_143170 seryl-tRNA synthetase, putative

827 PBANKA_070290 SET domain protein, putative yes

828 PBANKA_100390 sexual stage-specific protein precursor, putative

829 PBANKA_122200 sin3 associated polypeptide p18 protein, putative

830 PBANKA_110840 single-stranded DNA-binding protein, putative (SSB)

831 PBANKA_083580 small nuclear ribonucleoprotein (snRNP), putative

small ribosomal subunit processing microtubule-associated 832 PBANKA_070930 yes protein, putative

833 PBANKA_144040 small subunit rRNA processing factor, putative yes

834 PBANKA_061760 small subunit rRNA processing protein, putative

835 PBANKA_120700 small subunit rRNA processing protein, putative yes

836 PBANKA_121500 SMN-like protein

837 PBANKA_110860 SNAP protein, putative yes

838 PBANKA_145640 SNARE protein, putative

snoRNA-associated small subunit rRNA processing protein, 839 PBANKA_143280 putative

840 PBANKA_140200 sodium/hydrogen exchanger, Na , H antiporter, putative yes

841 PBANKA_091930 spermidine synthase, putative

842 PBANKA_130170 splicing factor 3A subunit 1, putative (SF3A1) yes

843 PBANKA_092440 splicing factor, putative yes

844 PBANKA_090210 sporozoite asparagine-rich protein (SLARP) yes

sporozoite surface protein 2,thrombospondin-related 845 PBANKA_134980 yes anonymous protein (TRAP)

846 PBANKA_092180 steryl ester hydrolase, putative

847 PBANKA_130420 stromal-processing peptidase, putative

848 PBANKA_080910 subunit of proteaseome activator complex, putative

849 PBANKA_061110 succinyl CoA ligase, putative

850 PBANKA_102250 surface protein, putative yes

851 PBANKA_094280 syntaxin, putative

TATA-box binding protein, putative,transcription initiation factor 852 PBANKA_110580 yes tfiid, putative (TBP)

853 PBANKA_020180 TatD-like deoxyribonuclease, putative

854 PBANKA_144410 t-complex protein 1 gamma subunit, putative 855 PBANKA_040520 T-complex protein beta subunit, putative yes

856 PBANKA_091620 TCP-1/cpn60 chaperonin family, putative yes

857 PBANKA_040650 TCP-1/cpn60 chaperonin, putative

858 PBANKA_113410 TCP-1/cpn60 chaperonin, putative

859 PBANKA_080510 TGF beta-inducible nuclear protein, putative

threonyl-tRNA synthetase, putative,threonine--tRNA ligase, 860 PBANKA_092230 yes putative (ThrRS)

861 PBANKA_010920 trancription factor, putative yes

862 PBANKA_101850 transcription factor 3b, putative

863 PBANKA_145750 transcription factor Tfb2, putative

864 PBANKA_021440 transcription factor with AP2 domain(s), putative (ApiAP2)

865 PBANKA_100180 transcription factor with AP2 domain(s), putative (ApiAP2) yes

866 PBANKA_120590 transcription factor with AP2 domain(s), putative (ApiAP2)

867 PBANKA_135600 transcription factor with AP2 domain(s), putative (ApiAP2) yes

868 PBANKA_136370 transcription factor with AP2 domain(s), putative (ApiAP2)

869 PBANKA_010910 transketolase, putative

870 PBANKA_134160 translation initiation factor EIF-2B gamma subunit, putative

871 PBANKA_141090 translation initiation factor IF-2, putative

872 PBANKA_100850 translocon component PTEX150 (PTEX150)

873 PBANKA_094130 translocon component PTEX88, putative yes

874 PBANKA_061100 transport protein particle (TRAPP) component, putative yes

875 PBANKA_030670 transporter, putative

876 PBANKA_090350 transporter, putative yes

877 PBANKA_130650 TRAP-like protein (TREP)

878 PBANKA_110790 triose phosphate transporter, putative

879 PBANKA_124460 triose phosphate transporter, putative

880 PBANKA_060610 tRNA delta(2)-isopentenylpyrophosphate transferase, putative

881 PBANKA_135620 tRNA guanosine-2'-O-methyltransferase, putative

882 PBANKA_092900 tRNA m(1)G methyltransferase, putative yes

883 PBANKA_092780 tRNA nucleotidyltransferase, putative

884 PBANKA_021420 tRNA pseudouridine synthase D, putative

885 PBANKA_051880 tRNA pseudouridine synthase D, putative yes

886 PBANKA_050230 tRNA pseudouridine synthase, putative

887 PBANKA_062050 tRNAHis guanylyltransferase, putative yes

888 PBANKA_135070 tryptophan - tRNA ligase, putative 889 PBANKA_146470 tryptophanyl-tRNA synthetase, putative yes

890 PBANKA_093050 tyrosine-tRNA ligase, putative

891 PBANKA_140540 U1 small nuclear ribonucleoprotein a, putative

892 PBANKA_103950 U1 small nuclear ribonucleoprotein C, putative

893 PBANKA_103760 U3 small nucleolar ribonucleoprotein, putative

U3 snoRNA-associated small subunit rRNA processing 894 PBANKA_134830 associated protein, putative

U3 snoRNA-associated small subunit rRNA processing protein, 895 PBANKA_113400 putative

U3 snoRNA-associated small subunit rRNA processing protein, 896 PBANKA_121150 yes putative

U3 snoRNA-associated small subunit rRNA processing protein, 897 PBANKA_131180 putative

898 PBANKA_141550 U4/U6.U5 tri-snRNP-associated protein 2, putative (USP39) yes

899 PBANKA_130720 U6 snRNA-associated Sm-like protein LSm5, putative (LSM5)

900 PBANKA_114120 UBA/THIF-type NAD/FAD binding protein, putative

901 PBANKA_134790 ubiquitin activating enzyme, putative yes

902 PBANKA_041680 ubiquitin specific protease, putative yes

903 PBANKA_135840 ubiquitin-conjugating enzyme, putative

904 PBANKA_145240 ubiquitin-like protein, putative

905 PBANKA_135660 UDP-N-acetylglucosamine pyrophosphorylase, putative

906 PBANKA_060380 UGA suppressor tRNA-associated antigenic protein, putative

907 PBANKA_142260 unspecified product (Sel3)

908 PBANKA_050120 up-regulated in infective sporozoites (UIS4)

909 PBANKA_091130 UVB-resistance protein UVR8 homologue, putative yes

910 PBANKA_133900 vacuolar protein sorting protein 52, putative

911 PBANKA_132560 valine -- tRNA ligase, putative

912 PBANKA_145430 vesicle fusion and protein sorting subunit 16, putative yes

913 PBANKA_083600 vesicle transport protein, putative yes

914 PBANKA_124500 XAP-5 DNA binding protein, putative

915 PBANKA_060050 XPA binding protein 1, putative yes

916 PBANKA_081870 XPA binding protein 1, putative yes

917 PBANKA_041240 zinc finger protein, putative yes

918 PBANKA_041360 zinc finger protein, putative yes

919 PBANKA_071270 zinc finger protein, putative yes 920 PBANKA_113480 zinc finger protein, putative yes

921 PBANKA_120770 zinc finger protein, putative

922 PBANKA_123270 zinc finger protein, putative yes

923 PBANKA_132370 zinc finger protein, putative

924 PBANKA_141970 zinc finger protein, putative yes

925 PBANKA_145800 zinc finger protein, putative yes

926 PBANKA_142220 zinc transporter, putative

927 PBANKA_100590 zinc-finger, RAN binding protein, putative

aMicroarray analysis were performed between AP2-G2(−) parasites and wild-type parasites after treatement with sulfadiazine. Genes that were upregulated more than twofold in AP2-G2(−) parasites compared with wild-type parasites are listed. bGene ID and functional annotation were attributed to each gene according to those in PlasmoDB. Target genes were sorted in alphabetical order of attributed functional annotations. Table S13. Sequences enriched in upstream regions of genes up-regulated in AP2-G2(–) parasitesa

six base sequence p-value motif 1 AACCAA 1.02E-06 2 CAACCA 3.16E-06 (A/G)CAAC 3 TTCTGA 3.98E-06 4 TAACCA 5.58E-06 5 TTTCTC 1.17E-05 6 TGCAAC 1.53E-05 (A/G)CAAC 7 ATAACC 2.91E-05 8 AACCAT 6.3E-05 9 TTGGTT 7.61E-05 10 TCGGAG 0.0001 11 AAACCA 0.000117 12 TGGTTA 0.000213 13 ACAACC 0.000218 (A/G)CAAC 14 GATCGA 0.000276 15 GTTGTA 0.000321 GTTG(T/C) 16 TACAAC 0.000333 (A/G)CAAC 17 TGGTTG 0.000407 GTTG(T/C) 18 GCAACC 0.000418 (A/G)CAAC 19 TTGGGG 0.000453 20 GGTTGC 0.00054 GTTG(T/C) aFisher’s exact test was performed in all six base sequences between upstream regions of genes listed in S12 and those of other P. berghei genes. bThe result is arranged from the sequence with the smallest p-value

Table S14. Primers used in this study

Primer name sequence AP2G2-GFP AP2G2-GFP F1 5´-aaactcgAGAAACAGAAGGAATAAGATGTAG-3´ AP2G2-GFP R1 5´-aaagctagcACAATCATAAAAATTTTTGATTTTTCT-3´ AP2G2-GFP F2 5´-aaaggatccGAGTAATAAATCACGATGTATATCT-3´ AP2G2-GFP R2 5´-aaagcggccgCTCAGCTCTCCATGATCAT-3´ AP2G2-GFP probe-F 5´-CAAGGATGGAATATCAATGGTGG-3´ AP2G2-GFP probe-R 5´-GTCCTCATTTAGAAATTCTTTGGTAT-3´ AP2-G2 KO AP2-G2-1 5´-ACCACGATAAAGGAGGCATGTAAC-3´ 5´-CTCATCTACAAGCATCgtcgacTCATCGTCTCCTTTCCT AP2-G2-2 C-3´ 5´-CCTTCAATTTCGgatccactagGTAATGTTGAAAGCGACA AP2-G2-3 G-3´ AP2-G2-4 5´-GTTGTATTATCAACTTGAGCAGTTTC-3´ AP2-G2-probe-R 5´-TTGAGCATCTGTGGAACGAC-3´ AP2-G2-probe-F 5´-CATGATAAATACATCAGGTAATCTC-3´ EMSA AP2-G2-GEX-F 5´-aaaggatccTCAAATTATGATATAAAATCTCCAAGG-3´ AP2-G2-GEX-R 5´-aaactcgagttaGTCCTCATTTAGAAATTCTTTGG-3´ Bio-EMSA-P28 Fnew 5´-CTACGATATAATCGAAAAAAAACATTTG-3´ Bio-EMSA-P28 Rnew 5´-GATGGATAATATGTGCTATTTCC-3´ P28 MUT F1 5´-TTTTAGCCTcTgTACATGGATTTAAAAAATTGTATCCTTT-3´ 5´-AAATCCATGTAcAgAGGCTAAAAAAAAAATTATAAGCAA P28 MUT R1 ATG-3´ Bio-MSP1-EMSA R 5´-CGGTACACAAATAAATAACATTGATATC-3´ MSP1-EMSA F 5´-AATGTCTAGATAATATATTTTTTTATATGCATG-3´ 5´-CTTTGTGTGTGgAACTTATTTTTTTTAATAATAATTATCC MSP-MUT-F AGATATC-3´ qPCR p28 qPCR-F 5´-AAAAAGCCCACACAATCTTACG-3´ p28 qPCR-R 5´-AATTTTTTAAATCCATGTAGACAGGC-3´ DHC qPCR-F2 5´-GTATATATGATTTCTGCATATACTCG-3´ DHC qPCR-R3 5´-TATAGTAATATAGAGAGTGCCTCC-3´ HAP2qPCR F 5´-ATAAATGGGCTAATGATATAGTTCC-3´ HAP2 qPCR R2 5´-CTTACGAATCTTGTCTTCCCTC-3´ MSP1 qPCR-F 5´-GCACTAAGAATATGCAAATGTCTAG-3´ MSP1 qPCR-R 5´-ACACACAAAGATTCGCACAAATC-3´ MSP7 qPCR-F 5´-GCACACATTATTATATGCATATGCAC-3´ MSP7 qPCR-R 5´-CAGACAAATTGCTGATTAAATCTAGC-3´ MCAT qPCR Fnew 5´-ATTTTCGTAGATATGTCGAGATCG-3´ MCAT qPCR Rnew 5´-CAATGAAAATTTGCAGCTATGCAC-3´ LISP2-qPCR R 5´-AATGGTTAAATCGATACGGAAGC-3´ LISP2-qPCR R2 5´-TGGATTTGTTCGATTTCAACTGC-3´ UIS3 qPCR-F 5´-CATTTCAGTGATAAAATATATTGAACC-3´ UIS3 qPCR-R 5´-GCCAATGAGATGTTATGCTAATGC-3´ Promoter assay LISP2 F 5´-aaaggtacCGATGTAACAGTGTTGTATATATTATTG-3´ LISP2-R 5´-aaagctagcATGATCTTTCATTTTTTATGTGTAAAAAAG-3´ 5´-CTTTAAAAATATACAAgTGTAATCCCTAATAAATGAATG LISP2-mut-F C-3´ LISP2-mut-R 5´-GGGATTACAcTTGTATATTTTTAAAGAACCGTC-3´ MCAT-up-F 5´-aaaggtaccGATTTTATAAATACAACAAAACTAACAAACC-3´ 5´-aaagctagcTTTCAAATGCATTTTGATTAATATTTAAACAA MCAT -up-R GTC-3´ 5´-CAAAAcTTGTAAAAAAAATAGCACAATTAATTATTTAAA MCAT-mut-F2 T-3´ 5´-GTGCTATTTTTTTTACAAgTTTTGATTTATTGACAATGA MCAT-mut-R2 AAATTTGC-3´