TITLE II DESCRIPTION • NCEZID provides advanced laboratory services—including The National Center for Emerging and Zoonotic Infectious the CDC’s high-containment biosafety labs that enable it National Center Diseases (NCEZID) at the U.S. Centers for Disease Control to study hazardous pathogens—and advanced molecular (CDC) works to protect people from antibiotic-resistant detection techniques that allow the CDC to identify illnesses for Emerging infections, foodborne outbreaks, emerging diseases, and of unknown origin from around the world. zoonotic infectious diseases—diseases that spread between & Zoonotic animals and people—such as Zika, Ebola, salmonella infection, WHY SHOULD AMERICANS CARE? and SARS-CoV-2, the virus that causes COVID-19. • NCEZID develops cutting-edge, point-of-care diagnostic Infectious tools, enabling faster, accurate detection of infectious WHAT DOES IT BUY? diseases that threaten U.S. health, including vector-borne Diseases Funding supports the development of diagnostic tools and diseases. the investigation of, and response to, disease outbreaks » Early in the 2016 Zika outbreak, NCEZID scientists Minimum Requirement F.Y. 2022 internationally, which includes surveillance, infection control, developed a diagnostic called the Trioplex that detects vaccine delivery, and health care worker training. Zika virus, dengue, and chikungunya in a single test. $715.53 million • More than 2.8 million antibiotic-resistant infections occur in WHY IS IT IMPORTANT? the U.S. annually, and as a result take the lives of more than F.Y. 2021 Enacted • Globally, zoonotic infectious diseases sicken 2.5 billion and 35,000 people. Modern travel of people, animals, and goods kill 2.7 million people every year. means an antibiotic-resistant organism can quickly become a $596.27 million • NCEZID investigates and responds to deadly disease global threat—yet global action has been limited. outbreaks internationally to keep them from becoming • NCEZID oversees 20 quarantine stations, strategically threats at home. located at U.S. airports, land borders, and seaports where » NCEZID assisted health officials in tracking cases, most international travelers arrive. training health workers, and began studying the effectiveness of a new vaccine during the 2017 COVID-19 IMPACTS monkeypox outbreak in the DRC. • NCEZID’s advanced laboratory services made it a leader of NCEZID » The 2016 typhoid fever outbreak in Harare, Zimbabwe, CDC’s COVID-19 response. investigates and during which NCEZID investigated and controlled the • From the earliest days of the outbreak, NCEZID conducted responds to outbreak that lasted nearly five months and caused 867 health screenings at U.S. airports, posted travel notices, deadly disease suspected cases and four deaths. provided infection control guidance, and distributed outbreaks • Rabies kills an estimated 59,000 people each year, with laboratory diagnostic kits for COVID-19. internationally to Haiti having the highest rate of human rabies deaths in • NCEZID’s Office of Advanced Molecular Detection is leading keep them from the Western Hemisphere at two deaths a week. In Haiti, a new genomics consortium to coordinate SARS-CoV-2 becoming threats at a CDC program has increased animal rabies surveillance sequencing that provides crucial information to track the home. 16-fold, decreased the risk of dying from rabies by 49%, and spread of the virus and identify diagnostic and therapeutic increased adherence to post-bite rabies vaccination by 230%. product targets. Labor, Health & Human Services Appropriations | Choose to Invest 2022 TITLE II WHAT MORE COULD BE DONE? field deployment in high-risk, remote, or resource-poor • In the wake of COVID-19, it is clear that U.S. investment regions of the world. National Center must match the increasing frequency and scale of disease • Increased funding could support domestic and international outbreaks worldwide. Some initiatives might include: responses to rabies and progress towards the World Health for Emerging » Rapidly deployable resources and teams of experts Organization’s goal of ending deaths due to canine rabies by to safely test for dangerous viral hemorrhagic fevers 2030. & Zoonotic (VHFs), such as Ebola, at their source before becoming • Additional investment could increase capacity, coordination, global pandemics. and tool development for waterborne disease surveillance, Infectious » Improved training, surveillance, and diagnostic communications, outbreak investigations, and emergency laboratory capacity for VHFs, monkeypox, other preparedness. Diseases emerging poxvirus diseases, and outbreaks of unknown and emerging pathogens. Minimum Requirement F.Y. 2022 » Improving molecular diagnostic tools, building on PEPFAR laboratory diagnostic networks, and optimizing $715.53 million diagnostic technologies and laboratory techniques for

F.Y. 2021 Enacted FUNDING HISTORY $596.27 million

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House Senate Funding levels may not exactly reflect those in the appropriations bills and/or reports due to rounding

Labor, Health & Human Services Appropriations | Choose to Invest 2022