Select Biological Agent and Toxin List

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Select Biological Agent and Toxin List HHS Non-Overlap Select Agents and Toxins USDA High Consequence Livestock Pathogens - Crimean-Congo haemorrhagic fever virus and Toxins (Non-Overlap agents and toxins) - Coccidioides posadasii - Akabane virus - Ebola viruses - African swine fever virus - Cercopithecine herpesvirus 1 (Herpes B virus) - African horse sickness virus - Lassa fever virus - Avian influenza virus (highly pathogenic) - Marburg virus - Blue tongue virus (Exotic) - Monkeypox virus - Bovine spongiform encephalopathy agent - Rickettsia prowazekii - Camel pox virus - Rickettsia rickettsii - Classical swine fever virus South American haemorrhagic fever viruses - Cowdria ruminantium (Heartwater) - Junin - Foot and mouth disease virus - Machupo - Goat pox virus - Sabia - Lumpy skin disease virus - Flexal - Japanese encephalitis virus - Guanarito - Malignant catarrhal fever virus (Exotic) Tick-borne encephalitis complex (flavi) viruses - Menangle virus - Central European tick-borne encephalitis - Mycoplasma capricolum/M.F38/M. mycoides capri - Far Eastern tick-borne encephalitis - Mycoplasma mycoides mycoides - Russian spring and summer encephalitis - Newcastle disease virus (VVND) - Kyasanur forest disease - Peste Des Petits Ruminants virus - Omsk hemorrhagic fever - Rinderpest virus - Variola major virus (Smallpox virus) - Sheep pox virus - Variola minor virus (Alastrim) - Swine vesicular disease virus - Yersinia pestis - Vesicular stomatitis virus (Exotic) - Abrin - Conotoxins - Diacetoxyscirpenol Plant Pathogens - Ricin - Liberobacter africanus - Saxitoxin - Liberobacter asiaticus - Shiga-like ribosome inactivating proteins - Peronosclerospora philippinensis - Tetrodotoxin - Phakopsora pachyrhizi - Plum Pox Potyvirus High Consequence Livestock Pathogens - Ralstonia solanacearum race 3, biovar 2 and Toxins/Select Agents (Overlap Agents) - Schlerophthora rayssiae var seae - Bacillus anthracis - Synchytrium endobioticum - Brucella abortus - Xanthomonas oryzae - Brucella melitensis - Xylella fastidiosa (citrus variegated chlorosis - Brucella suis strain) - Burkholderia mallei (formerly Pseudomonas mallei) - Burkholderia pseudomallei (formerly Pseudomonas pseudomallei) - Botulinum neurotoxin producing species of Clostridium - Coccidioides immitis -Coxiella burnetii - Eastern equine encephalitis virus - Hendra virus - Francisella tularensis - Nipah virus - Rift Valley fever virus - Venezuelan equine encephalitis virus - Botulinum neurotoxin - Clostridium perfringens epsilon toxin The list of SATs will be reviewed and republished - Shigatoxin biennially, or more often as needed, and revised as - Staphylococcal enterotoxin necessary. - T-2 toxin .

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Poxvirus and Rabies Branch (PRB) Fact Sheet
Poxvirus & Rabies Branch (PRB) The epidemiologists, laboratory scientists, and public health professionals in PRB are responsible for surveillance, control, and prevention of illness and death due to poxviruses and rabies. Our Work Laboratory Reference, Diagnostics, & Training PRB’s provides laboratory reference, diagnostic services, and trainings to state and local health departments, the Department of Defense (DOD), international organizations, and the Laboratory Response Network (over 150 labs across the U.S. prepared to respond to bioterrorism). PRB collaborates with the private sector to develop and evaluate novel diagnostic assays, therapeutics, and vaccines for rabies and pox-related viruses. The branch maintains high-containment laboratories (BSL3 &4) to safely conduct public health research. Research & Surveillance PRB conducts research studies on the microbiology, molecular biology, pathogenesis (disease process), ecology, and evolution of Our Pathogens poxviruses and rabies. The branch monitors the incidence rates of PRB’s Poxvirus Team provides subject matter these diseases in the U.S. and internationally. expertise on: Expert Consultation Orthopoxviruses, including PRB provides consultation regarding poxvirus and rabies- Smallpox associated diseases and their diagnoses, prevention, control, and Monkeypox treatments. Assistance is offered to healthcare providers, academic Cowpox institutions, state and local health departments, other government Vaccinia Virus agencies, and the general public. PRB collaborates with non- governmental organizations to develop risk communication Parapoxviruses, including tools for disease prevention. The branch provides training on Orf Virus simple surveillance techniques and trains healthcare workers on monkeypox in the Democratic Republic of the Congo (DRC). PRB Pseudocowpox collaborates with the national government of Haiti on a rabies surveillance and control program which includes health education, enhanced diagnostics, surveillance, and an extensive dog vaccination campaign.
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Imported Monkeypox, Singapore
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Emergence of Monkeypox — West and Central Africa, 1970–2017
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Systematic Review of Important Viral Diseases in Africa in Light of the ‘One Health’ Concept
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Monkeypox: a Neglected Viral Zoonotic Disease
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Monkeypox Virus Liberia, and the US (Ex-Ghana)
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