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CHEM 5800 Principles Of Materials Chemistry CHEMISTRY (CHEM) [1-4 credit hours] Tutorial in selected topics in materials chemistry. S/U grading only. CHEM 5100 Principles of Organic and Term Offered: Fall [4 credit hours] CHEM 6200 Study of coordination compounds with a focus on ligand bonding, [3 credit hours] electron counting, molecular orbital theory, reactivity, and . Advanced topics in green chemistry, including industrial applications, In addition, polymerization, structure-property relationships, and economy, safer solvent substitutions, alternatives assessment, commercial materials will be explored. A review of undergraduate-level green metrics (PMI, E-factor), basic life cycle analysis, and an general and topics with discussions concerning introduction to chemical toxicology. teaching these subjects is also included. Term Offered: Fall Term Offered: Summer CHEM 6210 CHEM 5160 Chemistry Laboratory Techniques Development [3 credit hours] [2 credit hours] This course will focus on the chemistry of air, water, and soil with specific Study of general and organic chemistry laboratory techniques, such as emphasis on the effects of human-made chemical products and by- the characterization, structural determination and reactions of organic products on the environment. Connections with green chemistry will be and inorganic compounds, with an emphasis on pedagogical aspects of highlighted. the techniques. Approved chemical safety goggles meeting the American Term Offered: Spring National Standard Z87.1-1968 must be worn by every student during every laboratory class meeting. CHEM 6300 Advanced Term Offered: Summer [4 credit hours] An overview of new techniques in analytical chemistry. Topics CHEM 5170 Chemistry Instrumentation Techniques include sample preparation and sampling, spectroscopic, separation, [2 credit hours] electrochemical, surface characterization and thermal methods. The study of advanced instrumentation techniques and structural Prerequisite: Permission of department. determination of organic and inorganic compounds with an emphasis Term Offered: Fall on pedagogical aspects of the techniques. Approved chemical safety goggles meeting the American National Standard Z87.1-1968 must be CHEM 6310 Separation Methods worn by every student during every laboratory class meeting. [3 credit hours] Prerequisites: CHEM 5160 with a minimum grade of D- The theory, design and application of separation methods. Topics include extraction techniques, gas, liquid, and supercritical fluid , CHEM 5230 Chemistry of Sustainable Materials affinity and chiral separation, and capillary electrophoresis. [4 credit hours] Term Offered: Spring Applications of the principles of chemistry to understand the issues related to a sustainable energy future. CHEM 6320 [4 credit hours] CHEM 5300 Principles Of Analytical Chemistry A fundamental study of electrochemical concepts, methods, [1-4 credit hours] instrumentation and applications. Tutorial in selected topics in analytical chemistry. S/U grading only. Term Offered: Spring Term Offered: Fall CHEM 6330 Spectroscopic Methods And Analysis Of Spectra CHEM 5400 Principles Of Organic Chemistry [4 credit hours] [1-4 credit hours] A comprehensive study of theory and instrumentation. Applications of Tutorial in selected topics in organic chemistry. S/U grading only. spectroscopic methods including spectral interpretation. Topics include Term Offered: Summer, Fall a study of absorption, emission, Raman, NMR, ESR, , CHEM 5500 Principles Of Biological Chemistry and related subjects. Important methodology and strategy in organic [1-4 credit hours] synthesis including disconnection and retrosynthetic analysis. Tutorial in selected topics in biological chemistry. S/U grading only. Term Offered: Spring Term Offered: Fall CHEM 6340 Mass Spectrometry CHEM 5600 Principles Of Inorganic And [4 credit hours] [1-4 credit hours] The principles and applications of mass spectrometry in chemistry, Tutorial in selected topics in inorganic and organometallic chemistry. S/U , and related disciplines. Prerequisite: Admitted to the grading only. graduate program. Term Offered: Summer, Fall CHEM 5700 Principles Of [1-4 credit hours] Tutorial in selected topics in physical chemistry. S/U grading only. Term Offered: Spring, Fall

Chemistry (CHEM) 1 2 Chemistry (CHEM)

CHEM 6350 Separation Methods Laboratory CHEM 6500 Advanced Biological Chemistry [1 credit hour] [4 credit hours] Experiments covering topics discussed in CHEM 6310 lectures. Five The chemistry of cellular and molecular transformations in biochemical hours of laboratory per week. Approved chemical safety goggles meeting systems. Molecular structure of proteins, nucleic acids and membranes. the American National Standard 287.1-1968 must be worn by every Metabolism and of carbohydrates, amino acids and lipids; student during every laboratory class meeting. gene regulation and replication. Corequisites: CHEM 6310 Term Offered: Fall Term Offered: Spring CHEM 6510 Protein Chemistry CHEM 6400 Advanced Organic Chemistry [4 credit hours] [4 credit hours] A detailed analysis of the structure and function of proteins. Current This course deals with chemical structure and reactivity methodology for the analysis of structure, the basis for molecular correlations applied to the study of mechanisms; associations and relationships between structure and biological function. stereochemical features including conformation and stereoelectronic Prerequisites: CHEM 6500 with a minimum grade of D- effects; reaction dynamics, isotope effects and molecular orbital theory Term Offered: Spring applied to pericyclic and photochemical reactions; and special reactive CHEM 6520 Enzymology intermediates including carbenes, carbanions, and free radicals. [4 credit hours] Term Offered: Fall Survey of current methods to study enzyme-catalyzed reactions, and CHEM 6410 application to examples from major enzyme, groups. Current topics in [4 credit hours] enzymology include abzymes and ribozymes, artificial enzymes, and Important methodology and strategy in organic synthesis including enzymes, and enzyme engineering. disconnection and retrosynthetic analysis. Term Offered: Spring Term Offered: Spring CHEM 6530 Nucleic Acid Chemistry CHEM 6420 Topics in Modern Organic Chemistry [4 credit hours] [4 credit hours] The structural and chemical properties of nucleic acids and the resulting This course is designed to introduce groundbreaking topics and biological consequences. Topics include: 3D structures, conformation, technologies in organic chemistry over the past decades including new protein/nucleic acid interactions, physical properties and chemical methods in heterocylic chemistry and applications, , reactions, mutagenesis, damage/repair, and recombination. electrocatalysis, enzymatic catalysis, and advances in transition metal Prerequisites: CHEM 6500 with a minimum grade of D- catalysis. Term Offered: Spring Term Offered: Spring CHEM 6540 Macromolecular CHEM 6430 [2 credit hours] [4 credit hours] Fundamental theory and practical application of X-ray diffraction to Qualitative and quantitative aspects of the design of new therapeutic macromolecular structure determination, including protein crystallization agents are discussed. Approaches to the design of drugs and new and manipulation, data collection and reduction, phase solution, electron therapeutic modalities directed at enzymes, receptors, membrane density interpretation, structural refinement and validation. transport proteins and nucleic acids will be examined. Prerequisites: CHEM 6850 with a minimum grade of D- Term Offered: Fall Term Offered: Spring CHEM 6440 CHEM 6550 Practical Protein Crystallography [4 credit hours] [2 credit hours] Topics in carbohydrate chemistry, including of Hands-on training in protein crystallography. Laboratory projects complex oligosaccharides, complex glycoconjugates (glycolipids, include: protein crystallization, crystal manipulation and mounting, X-ray glycopeptides, and glycoproteins). diffraction data collection, data reduction, structure solution, electron Term Offered: Fall density interpretation, refinement and cultural validation. CHEM 6450 Organic Reaction Mechanisms Prerequisites: CHEM 6850 with a minimum grade of D- Term Offered: Spring [3 credit hours] This course focuses on a thorough treatment of synthetic chemistry CHEM 6570 through so-called Named Reactions, as well as extensive study of [4 credit hours] the underlying mechanisms. Course is often conducted as a “flipped Principles and applications of physical chemistry as applied to biological classroom”, and will require viewing pre-recorded lectures outside of macromolecules (i.e., proteins and nucleic acids in solution), including the scheduled class time to allow in class time to focus on practical thermodynamics, kinetics and of macromolecular applications of course material. interactions. Term Offered: Fall Term Offered: Fall

Chemistry (CHEM) 2 Chemistry (CHEM) 3

CHEM 6580 CHEM 6800 Advanced Materials Chemistry [4 credit hours] [4 credit hours] Survey of biologically important metals and metal-ligand complexes, and Introduction to important classes of solids, including conductors, the role of metal in proteins, metal transport and regulation, and magnetic materials, ferroelectrics, glasses, microporous materials, metals in medicine. organic solids. Traditional and novel synthetic approaches, structure/ property relationships, and characterization methods specific to solids. CHEM 6600 Physical Inorganic Chemistry [4 credit hours] Term Offered: Spring Symmetry, bonding theories, magnetism, and spectroscopic CHEM 6810 I characterization of inorganic compounds are described. Coverage of [4 credit hours] spectroscopic techniques such as NMR, EPR, UV/VIS, IR, AND Mossbauer A generic materials science approach to the study of crystalline focus on applications to inorganic systems. structure and defects (point, line and planar) in crystalline materials. The Term Offered: Fall mechanisms and kinetics of diffusion in the condensed state. CHEM 6610 Chemistry of Transition and Post-Transition Elements Term Offered: Fall [4 credit hours] CHEM 6820 Materials Science II The organometallic chemistry of the transition metals, lanthanides and [4 credit hours] actinides is described. Synthesis, structure, bonding, and reactivity A materials science approach to the thermodynamics of condensed state are considered. Applications in catalysis, bioinorganic, and materials equilibria. Phase transformation kinetics. chlemistry are discussed. Term Offered: Spring Term Offered: Fall CHEM 6830 Nanomaterials Science CHEM 6620 Chemistry of the Main Group Elements [4 credit hours] [4 credit hours] This survey course is intended to serve as an introduction to The inorganic and organomethallic chemistry of main group elements is nanotechnology for non-specialists. It is accessible to students in described. Synthesis, structure, bonding, and reactivity are considered. any technical major, including (all divisions), physicists, The use of main group reagents in synthesis, catalysis, and materials and engineers. The fundamentals of nanotechnology will be chemistry are discussed. covered, including the origin of nanoscale properties, synthesis and Term Offered: Spring characterization of nanomaterials (e.g. colloids, nanoparticles, nanowires, CHEM 6700 Advanced Physical Chemistry nanotubes, DNA-based structures), fabrication of larger-scale structures [4 credit hours] (e.g. self assembly, lithography), and characterization techniques (e.g. Chemical systems and processes in the context of classical equilibrium microscopy, microanalysis, spectroscopy). Applications will also be thermodynamics. It introduces non-equilibrium and statistical discussed. themodynamics to elucidate chemical changes and the connection Term Offered: Spring, Fall between molecular and macroscopic system properties. CHEM 6850 X-Ray Crystallography Term Offered: Fall [4 credit hours] CHEM 6710 and Spectroscopy Theory and practice of structure determination by X-ray diffraction. [4 credit hours] Basics of symmetry, diffraction, and reciprocal space. Hands-on Fundamental principles of and their application introduction to single-crystal and powder methods. to model systems, and ; Introduction to molecular Term Offered: Fall spectroscopy. CHEM 6920 Chemistry Colloquium Term Offered: Spring [1-4 credit hours] CHEM 6720 Modern Topics in Physical Chemistry Presentations on research or current literature. [4 credit hours] Term Offered: Spring, Summer, Fall Advanced topics of current interest is physical chemistry. Examples CHEM 6930 Chemistry Seminar of topics include nanomaterials science, spectroscopic techniques, or [1-2 credit hours] molecular modeling. Seminars conducted by individual members of the department. Term Offered: Spring, Fall Term Offered: Spring, Fall CHEM 6730 Molecular Modeling CHEM 6940 Scientific Communication [4 credit hours] [1-2 credit hours] CHEM 6730 Molecular Modeling [4 credit hours]. Theory and techniques Instructions on different modes of scientific communication : written of contemporary molecular modeling, and their application to calculate communication, oral presentation, and research proposal, to enable physical and chemical properties of realistic molecular systems. students to think and converse competently in the language of science. Term Offered: Fall Term Offered: Spring, Fall

Chemistry (CHEM) 3 4 Chemistry (CHEM)

CHEM 6960 Thesis Research CHEM 8300 Advanced Analytical Chemistry [1-15 credit hours] [4 credit hours] Original investigations of significant chemical problems at the master's An overview of new techniques in analytical chemistry. Topics level under the guidance of a member of the faculty. include sample preparation and sampling, spectroscopic, separation, Term Offered: Spring, Summer, Fall electrochemical, surface characterization and thermal methods. Term Offered: Fall CHEM 6970 Graduate Professional Internship [1-6 credit hours] CHEM 8310 Separation Methods Academic adviser approved industrial or non profit internship to provide [3 credit hours] an experiential learning component to the MS and PhD degrees in The theory, design and application of separation methods. Topics include chemistry, including the Professional Science Masters Degree in Green extraction techniques, gas, liquid, and supercritical fluid chromatography, Chemistry and Engineering. affinity and chiral separation, and capillary electrophoresis. CHEM 6980 Special Topics In Chemistry Term Offered: Spring [1-4 credit hours] CHEM 8320 Electrochemistry Discussions of newly developing areas in chemistry research. [4 credit hours] Term Offered: Spring, Fall A fundamental study of electrochemical concepts, methods, CHEM 7300 Principles Of Analytical Chemistry instrumentation and applications. Prerequisite: Permission of [1-4 credit hours] department. Tutorial in selected topics in analytical chemistry. S/U grading only. Term Offered: Spring Term Offered: Fall CHEM 8330 Spectroscopic Methods And Analysis Of Spectra CHEM 7400 Principles Of Organic Chemistry [4 credit hours] [1-4 credit hours] A comprehensive study of theory and instrumentation. Applications of Tutorial in selected topics in organic chemistry. S/U grading only. spectroscopic methods including spectral interpretation. Topics include Term Offered: Fall a study of absorption, emission, Raman, NMR, ESR, mass spectrometry, and related subjects. Important methodology and strategy in organic CHEM 7500 Principles Of Biological Chemistry synthesis including disconnection and retrosynthetic analysis. [1-4 credit hours] Term Offered: Spring Tutorial in selected topics in biological chemistry. S/U grading only. Term Offered: Spring, Fall CHEM 8340 Mass Spectrometry [4 credit hours] CHEM 7600 Principles Of Inorganic And Organometallic Chemistry The principles and applications of mass spectrometry in chemistry, [1-4 credit hours] biochemistry, and related disciplines. Prerequisite: Admitted to the Tutorial in selected topics in inorganic and organometallic chemistry. S/U graduate program. grading only. Term Offered: Fall CHEM 8350 Separation Methods Laboratory [1 credit hour] CHEM 7700 Principles Of Physical Chemistry Experiments covering topics discussed in CHEM 8310 lectures. Five [1-4 credit hours] hours of laboratory per week. Approved chemical safety goggles meeting Tutorial in selected topics in physical chemistry. S/U grading only. the American National Standard 287.1-1968 must be worn by every Term Offered: Fall student during every laboratory class meeting. CHEM 7800 Principles Of Materials Chemistry Corequisites: CHEM 8310 [1-4 credit hours] Term Offered: Spring Tutorial in selected topics in materials chemistry. S/U grading only. CHEM 8400 Advanced Organic Chemistry Term Offered: Fall [4 credit hours] CHEM 8200 Green Chemistry This course deals with chemical structure and reactivity [3 credit hours] correlations applied to the study of organic reaction mechanisms; Advanced topics in green chemistry, including industrial applications, stereochemical features including conformation and stereoelectronic atom economy, safer solvent substitutions, alternatives assessment, effects; reaction dynamics, isotope effects and molecular orbital theory green metrics (PMI, E-factor), basic life cycle analysis, and an applied to pericyclic and photochemical reactions; and special reactive introduction to chemical toxicology. intermediates including carbenes, carbanions, and free radicals. Term Offered: Fall Term Offered: Fall CHEM 8210 Environmental Chemistry CHEM 8410 Organic Synthesis [3 credit hours] [4 credit hours] This course will focus on the chemistry of air, water, and soil with specific Important methodology and strategy in organic synthesis including emphasis on the effects of human-made chemical products and by- disconnection and retrosynthetic analysis. products on the environment. Connections with green chemistry will be Term Offered: Spring highlighted. Term Offered: Spring

Chemistry (CHEM) 4 Chemistry (CHEM) 5

CHEM 8420 Topics in Modern Organic Chemistry CHEM 8530 Nucleic Acid Chemistry [4 credit hours] [4 credit hours] This course is designed to introduce groundbreaking topics and The structural and chemical properties of nucleic acids and the resulting technologies in organic chemistry over the past decades including new biological consequences. Topics include: 3D structures, conformation, methods in heterocylic chemistry and applications, photochemistry, protein/nucleic acid interactions, physical properties and chemical electrocatalysis, enzymatic catalysis, and advances in transition metal reactions, mutagenesis, damage/repair, and reconbination. catalysis. Prerequisites: CHEM 6500 with a minimum grade of D- or CHEM 8500 Term Offered: Spring with a minimum grade of D- CHEM 8430 Medicinal Chemistry Term Offered: Spring [4 credit hours] CHEM 8540 Macromolecular Crystallography Qualitative and quantitative aspects of the design of new therapeutic [2 credit hours] agents are discussed. Approaches to the design of drugs and new Fundamental theory and practical application of X-ray diffraction to therapeutic modalities directed at enzymes, receptors, membrane macromolecular structure determination, including protein crystallization transport proteins and nucleic acids will be examined. and manipulation, data collection and reduction, phase solution, electron Term Offered: Fall density interpretation, structural refinement and validation. CHEM 8440 Carbohydrate Chemistry Prerequisites: CHEM 6850 with a minimum grade of D- or CHEM 8850 [4 credit hours] with a minimum grade of D- Topics in carbohydrate chemistry, including chemical synthesis of Term Offered: Spring complex oligosaccharides, complex glycoconjugates (glycolipids, CHEM 8550 Practical Protein Crystallography glycopeptides, and glycoproteins). [2 credit hours] Term Offered: Fall Hands-on training in protein crystallography. Laboratory projects CHEM 8450 Organic Reaction Mechanisms include: protein crystallization, crystal manipulation and mounting, X-ray [3 credit hours] diffraction data collection, data reduction, structure solution, electron This course focuses on a thorough treatment of synthetic chemistry density interpretation, refinement and cultural validation. through so-called Named Reactions, as well as extensive study of Prerequisites: CHEM 8850 with a minimum grade of D- the underlying mechanisms. Course is often conducted as a “flipped Term Offered: Spring classroom”, and will require viewing pre-recorded lectures outside of CHEM 8570 Biophysical Chemistry the scheduled class time to allow in class time to focus on practical [4 credit hours] applications of course material. Principles and applications of physical chemistry as applied to biological Term Offered: Fall macromolecules (i.e., proteins and nucleic acids in solution), including CHEM 8500 Advanced Biological Chemistry thermodynamics, kinetics and spectroscopy of macromolecular [4 credit hours] interactions. The chemistry of cellular and molecular transformations in biochemical Term Offered: Fall systems. Molecular structure of proteins, nucleic acids and membranes. CHEM 8580 Bioinorganic Chemistry Metabolism and biosynthesis of carbohydrates, amino acids and lipids; [4 credit hours] gene regulation and replication. Survey of biologically important metals and metal-ligand complexes, and Term Offered: Fall the role of metal ions in proteins, metal ion transport and regulation, and CHEM 8510 Protein Chemistry metals in medicine. [4 credit hours] CHEM 8600 Advanced Inorganic And Organometallic Chemistry A detailed analysis of the structure and function of proteins. Current [4 credit hours] methodology for the analysis of structure, the basis for molecular Symmetry, bonding theories, magnetism, and spectroscopic associations and relationships between structure and biological function. characterization of inorganic compounds are described. Coverage of Prerequisites: CHEM 6500 with a minimum grade of D- or CHEM 8500 spectroscopic techniques such as NMR, EPR, UV/VIS, IR, AND Mossbauer with a minimum grade of D- focus on applications to inorganic systems. Term Offered: Spring Term Offered: Fall CHEM 8520 Enzymology CHEM 8610 Chemistry of Transition and Post-Transition Elements [4 credit hours] [4 credit hours] Survey of current methods to study enzyme-catalyzed reactions, and The organometallic chemistry of the transition metals, lanthanides and application to examples from major enzyme, groups. Current topics in actinides is described. Synthesis, structure, bonding, and reactivity enzymology include abzymes and ribozymes, artificial enzymes, and are considered. Applications in catalysis, bioinorganic, and materials enzymes, and enzyme engineering. chemistry are discussed. Term Offered: Spring Term Offered: Fall

Chemistry (CHEM) 5 6 Chemistry (CHEM)

CHEM 8620 Chemistry of the Main Elements CHEM 8830 Nanomaterials Science [4 credit hours] [4 credit hours] The inorganic and organometallic chemistry of main group elements is This survey course is intended to serve as an introduction to described. Synthesis, structure, bonding, and reactivity are considered. nanotechnology for non-specialists. It is accessible to students in The use of main group reagents in synthesis, catalysis, and materials any technical major, including chemists (all divisions), physicists, chemistry are discussed. and engineers. The fundamentals of nanotechnology will be Term Offered: Spring covered, including the origin of nanoscale properties, synthesis and CHEM 8700 Advanced Physical Chemistry characterization of nanomaterials (e.g. colloids, nanoparticles, nanowires, [4 credit hours] nanotubes, DNA-based structures), fabrication of larger-scale structures Chemical systems and processes in the context of classical equilibrium (e.g. self assembly, lithography), and characterization techniques (e.g. thermodynamics. It introduces non-equilibrium and statistical microscopy, microanalysis, spectroscopy). Applications will also be themodynamics to elucidate chemical changes and the connection discussed. between molecular and macroscopie system properties. Term Offered: Spring, Fall Term Offered: Fall CHEM 8850 X-Ray Crystallography CHEM 8710 Quantum Chemistry and Spectroscopy [4 credit hours] [4 credit hours] Theory and practice of structure determination by X-ray diffraction. Fundamental principles of quantum mechanics and their application Basics of symmetry, diffraction, and reciprocal space. Hand-on to model systems, atoms and molecules; Introduction to molecular introduction to single-crystal and powder methods. spectroscopy. Term Offered: Fall Term Offered: Spring CHEM 8920 Chemistry Colloquium CHEM 8720 Modern Topics in Physical Chemistry [1-4 credit hours] [4 credit hours] Presentations on research or current literature. Advanced topics of current interest is physical chemistry. Examples Term Offered: Spring, Summer, Fall of topics include nanomaterials science, spectroscopic techniques, or CHEM 8930 Chemistry Seminar molecular modeling. [1-2 credit hours] Term Offered: Spring, Fall Seminars conducted by individual members of the Department. CHEM 8730 Molecular Modeling Term Offered: Spring, Fall [4 credit hours] CHEM 8940 Scientific Communication CHEM 8730 Molecular Modeling [4 credit hours]. Theory and techniques [1 credit hour] of contemporary molecular modeling, and their application to calculate Instructions on different modes of scientific communication: written physical and chemical properties of realistic molecular systems. communication, oral presentation, and research proposal to enable Term Offered: Fall students to think and converse competently in the language of science. CHEM 8800 Advanced Materials Chemistry Term Offered: Spring, Fall [4 credit hours] CHEM 8960 Dissertation Research Introduction to important classes of solids, including conductors, [1-15 credit hours] magnetic materials, ferroelectrics, glasses, microporous materials, Original investigations of significant chemical problems at the Doctoral organic solids. Traditional and novel synthic approaches, structure/ level under the guidance of a member of the faculty. property relationships, and characterization methods specific to solids. Term Offered: Spring, Summer, Fall Term Offered: Spring CHEM 8970 Graduate Professional Internship CHEM 8810 Materials Science I [1-6 credit hours] [4 credit hours] Academic adviser approved industrial or non profit internship to provide A generic materials science approach to the study of crystalline an experiential learning component to the M.S. and Ph.D. degrees in structure and defects (point, line and planar) in crystalline materials. The chemistry, including the Professional Science Masters Degree in Green mechanisms and kinetics of diffusion in the condensed state. Chemistry and Engineering. Term Offered: Fall CHEM 8980 Special Topics In Chemistry CHEM 8820 Materials Science II [1-4 credit hours] [4 credit hours] Discussions of newly developing areas in chemistry research. A materials science approach to the thermodynamics of condensed state Term Offered: Spring, Fall equilibria. Phase transformation kinetics. Term Offered: Spring

Chemistry (CHEM) 6