Institut Dermed Clarifying Product Knowledge

Home , Azelaic acid, Benzoyl peroxide, Glycolic acid, Keratolytic, Sulfur (pharmacy)

Clarify Acne l, ll, lll & IV

Acne is a disorder of the sebaceous glands that presents a variety of lesions; blackheads, pimples, pustules, papules, cysts and nodules on the face, chest and back. These lesions are classified as Acne Grades l, ll, lll & lV to identify their type as mild, moderate or severe for appropriate treatment. Acne occurs as a result of excessive sebum (oil) production mixing with keratinized (dead) cells in the philosebaceous unit (hair follicle). This creates a microplug or intra-cellular adhesion called a comedone. Comedones, the plural form of comedo, are the primary sign of acne, consisting of a dilated (widened) hair follicle filled with keratin squamae (skin debris), bacteria, and sebum (oil). Comedones may be closed or open. A closed comedo has an obstructed opening to the skin and may rupture to cause a low-grade inflammatory reaction in the skin. The common name for a closed comedo is a whitehead. An open comedo has a wide opening to the skin and is capped with a blackened mass of skin debris. It is commonly known as a blackhead. Acne occurs when sebaceous glands of the skin begin to secrete oil during puberty. These glands are stimulated by male hormones that are produced in the adrenal glands of both boys and girls. Clarify

Clarifying Cleanser Purify and prevent clogged pores with the Institut’ DERMed Clarifying Cleanser formulated with Salicylic Acid and Tea Tree Oil to decongest and detoxify skin for a clear, clean complexion.

Key Ingredient Benefits • Glycolic Acid 5% an alpha hydroxy acid (AHA) derived from fermented rhubarb used to reduce corneocyte cohesion, a thickening of the skin where excess dead skin cells build up. It is also known to help stimulate and strengthen collagen and elastin production for smoother, younger looking skin. • Salicylic Acid 1% a beta hydroxy acid (BHA) derived from wintergreen tree bark used to help clear and prevent acne breakout. Topical salicylic acid is also a keratolytic agent used to treat skin conditions that involve scaling or overgrowth of skin cells such as psoriasis, ichthyoses, dandruff, corns, calluses, and warts on the hands or feet. It is also a gentle alternative to benzoyl peroxide for reducing redness and decongesting the skin. • Tea Tree Oil anti-inflammatory, antibacterial shown to be effective in controlling the edema often associated with acne, supporting cellular regeneration and wound healing Ingredients:

Water, Glycerin, PEG-150 Pentaerythrityl Tetrastearate, Key Selling Points Hamamelis Virginiana (Witch Hazel) Extract, Panthenol, Disodium Laureth Sulfosuccinate, Cocamidopropyl Betaine, PEG-18 Glyceryl Oleate/Cocoate, Lactic Acid, Azelaic • Antiseptic, decongesting Acid, Salicylic Acid, Decyl Glucoside, Tocopheryl Acetate, Phenoxyethanol, Ethylhexylglycerin, Hydrolyzed Soy Protein, • Controls inflammatory acne without dehydrating the skin Rosmarinus Officinalis (Rosemary) Leaf Extract, Camellia Sinensis (Green Tea) Leaf Extract, Citrus Gandis (Grapefruit) • Helps to prevent scarring Peel Oil, Eucalyptus Globulus Leaf Oil, Citrus Aurantium Dulcis (Orange) Peel Oil, Melaleuca Alternifolia (Tea Tree) Leaf Oil, Saccharum Officinarum (Sugarcane) Extract, Personalized Prescription Citrus Medica Limonum (Lemon) Fruit Extract, Citrus Aurantium Dulcis (Orange) Fruit Extract, Pyrus Malus • For corrective treatment, apply like a mask and leave on (Apple) Fruit Extract, Camellia Sinensis (Green Tea) Leaf Extract, Glycolic Acid, Citric Acid the skin for 60 seconds Presentation: • Alternate with another cleanser to adjust intensity of treatment • 2 oz/60 ml bottle • 4 oz/118 ml bottle • 8 oz/237 ml bottle Directions for Use Wet hands and apply a small amount to finger tips. Massage onto face and neck in upward circular motions for thirty to sixty seconds avoiding direct contact with the eyes. Rinse thoroughly. For best results, use twice daily, morning and evening. Follow with the Institut’ DERMed Clarifying Toner. notes

5589 Peachtree Road Atlanta, Georgia 30341 phone 770.454.7788 • www.idermed.com © 2011 Institut’ DERMed clinical skincare Clarify Clarifying Toner Balance and detoxify your skin with the Institut’ DERMed Clarifying Toner formulated with Glycolic Acid and Salicylic Acid to exfoliate and decongest clogged pores for a clear, clean complexion.

Key Ingredient Benefits • Glycolic Acid 3% an alpha hydroxy acid (AHA) derived from fermented rhubarb used to reduce corneocyte cohesion a thickening of the skin where excess dead skin cells build up. It is also known to help stimlate and strengthen collagen and elastin production for smoother, younger looking skin. • Salicylic Acid 1% a beta hydroxy acid (BHA) derived from willow tree bark used to help clear and prevent acne breakout. Topical salicylic acid is also a keratolytic agent used to treat skin conditions that involve scaling or overgrowth of skin cells such as psoriasis, ichthyoses, dandruff, corns, calluses, and warts on the hands or feet. It is also a gentle alternative to benzoyl peroxide for reducing redness and decongesting the skin. • L-Lactic Acid 1% an alternative to glycolic acid derived from sour milk that increases cellular desquamation to refine and re-texturize the skin.

Key Selling Points Ingredients: • Deep cleanses clogged pores SD Alcohol 40-B, Hamamelis Virginiana (Witch Hazel) • Stimulates deep exfoliation Extract, Glycolic Acid, Salicylic Acid, Lactic Acid, Saccharum Officinarum (Sugarcane) Extract, Citrus • Prevents follicular adhesions that cause acne Medica Limonum (Lemon) Fruit Extract, Pyrus Malus (Apple) Fruit Extract, Camellia Sinensis (Green Tea) Leaf Extract Presentation: Personalized Prescription • 2 oz/60 ml bottle • 4 oz/118 ml bottle • Alternate with another toner to adjust intensity of treatment • 8 oz/237 ml bottle • Use on cotton in the morning and evening to lift impurities

Directions for Use Apply to the face with a cotton pad. For best results, use twice daily, morning and evening. Follow with an Institut’ DERMed Clarifying Serum and Moisturizer. notes

Glycolic Serum Gain control of your skin with the Institut’ DERMed Glycolic Serum. This potent serum formulated with Glycolic Acid and Sodium PCA decongests and detoxifies clogged pores reducing and clearing blemishes for a clean, clear complexion.

Key Ingredient Benefits • Glycolic Acid 15% an alpha hydroxy acid (AHA) derived from sugarcane that increases desquamation to refine the skin’s surface • Sodium PCA a non-comedogenic natural humectant and effective moisture- binding agent that preserves the natural moisturizing factor (NMF) of the skin

Key Selling Points • Dissolves and controls oil • Decongests pores • Refines skin texture Ingredients: • Prevents acne breakout

Aloe Barbadensis (Aloe) Leaf Juice, Glycolic Acid and Sodium Glycolate, Lavandula Angustifolia (Lavender) Extract, Personalized Prescription Arnica Montana Flower Extract, Calendula Officinalis Flower Extract, Carbomer, Cyamopsis Tetragonoloba (Guar) Gum, Sodium Hyaluronate, Sodium PCA, Sodium Hydroxide, • Use 3x weekly and gradually increase as tolerance indicates Phenoxyethanol, Sodium Benzoate • May be used as a moisturizer for oily skin Presentation: • 0.5 oz/15 ml pump bottle • Alternate with another treatment to adjust intensity Directions for Use Smooth onto face with finger tips until absorbed. For best results, use two to three times a week in the evening. Follow with the Institut’ DERMed Clarifying Moisturizer. You may experience mild tingling or redness. This is normal and should be temporary until your skin adjusts. notes

Totarol Serum Gain control of your skin with the Institut’ DERMed Totarol Serum. This potent detoxifying serum formulated with Azelaic Acid and Glycolic Acid eliminates and prevents reoccurring blemishes for a clear, clean complexion.

Key Ingredient Benefits • Totarol a potent antibacterial and anti-inflammatory derived from the Totara Tree in New Zealand, used as a gentle alternative to benzoyl peroxide • Glycolic Acid 2% an alpha hydroxy acid (AHA) derived from sugarcane that thins the stratum corneum to refine the skins surface

Key Selling Points • Suppresses the bacteria that causes acne • Prevents, heals and reduces acne breakouts and potential scarring Ingredients: • Excellent for acneic, sensitive skins

Hamamelis Virginiana (Witch Hazel) Water, Alcohol Denat., Aqua (Water), Glycerin, Azelaic Acid, Niacinamide, Salicylic Acid, Glycolic Acid, Totarol, Bisabolol (L-alpha), Personalized Prescription Melaleuca Alternifolia (Tea Tree) Leaf Oil, Eucalyptus Globulus Leaf Extract, Citrus Grandis (Grapefruit) • Use PM as a spot treatment Peel Oil, Zeolite, Cholic Acid (D), Allantoin, Lonicera Japonica (Honeysuckle) Flower Extract, Sodium • Alternate with another corrective serum to adjust treatment Hyaluronate (L), Lonicera Caprifolium (Honeysuckle) Flower Extract, Citric Acid, Tetrahydrodiferuloylmethane, Tetrahydrobisdemethoxydiferuloylmethane, Directions for Use Tetrahydrodemethoxydiferuloylmethane, Xanthan Gum, Hydroxypropyl Methylcellulose, Sodium Chloride, Potassium Sorbate, Hydrogen Peroxide Smooth onto affected areas of the face with finger tips until absorbed. For best results, use two to three times a week Presentation: in the evening. Follow with the Institut’ DERMed Clarifying • 0.5 oz/15 ml pump bottle Moisturizer. You may experience mild tingling or redness. This is normal and should be temporary until your skin adjusts.

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Clarifying Moisturizer Protect your skin from dehydration with the Institut’ DERMed Clarifying Moisturizer formulated with plant derived Squalene Oil and Tea Tree Oil to restore the skin’s ideal moisture balance and detoxify pores for a clean, clear complexion.

Key Ingredient Benefits • Tea Tree Oil anti-inflammatory, antibacterial shown to be effective in controlling the edema often associated with acne, supporting cellular regeneration and wound healing • Squalene Oil derived from olive oil and used as an anti-oxidant to prevent dehydration, softening the appearance of fine lines and wrinkles

Key Selling Points • Moisture retentive for deep hydration Ingredients: • Stimulates the skin’s immune response

Water, Glycerin, Helianthus Annuus (Sunflower) Seed Oil, • Prevents dehydration in premature aging skin Caprylic/Capric Triglyceride, Prunus Armeniaca (Apricot) Kernel Oil, Saccharide Isomerate, Punica Granatum Extract, Squalane, Orbignya Speciosa Kernel Oil, Xanthan Gum, Algae Extract, Pyrus Malus (Apple) Fruit Extract, Astrocaryum Personalized Prescription Murumuru Seed Butter, Melaleuca Alternifolia (Tea Tree) Leaf Oil, Chlorella Vulgaris Extract/Lupinus Albus Protein Ferment, • Apply under sun protection in the morning for Pectin, Hydrolyzed Glycosaminoglycans, Sodium Hyaluronate, additional hydration Foeniculum Vulgare (Fennel) Fruit Extract, Isohexadecane, Polysorbate-80, PPG-3 Benzyl Ether Myristate, Acrylamide/ Sodium, Acryloyldimethyltaurate Copolymer, Iodopropynyl Butylcarbamate, Phenoxyethanol, Essential Oils Directions for Use Presentation: Smooth onto the face and neck with finger tips until • 1 oz/30 ml pump bottle absorbed. For best results, use twice daily, morning and • 1.67 oz/50 ml pump bottle evening. For added protection during the day, follow with the Institut’ DERMed Brightening Moisturizer.

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Clarifying Matte Fluid Protect your skin from dehydration with the Institut’ DERMed Clarifying Matte Fluid formulated with Grapefruit Peel Oil and Phytic Acid to restore moisture balance and prevent reoccurring breakouts for a clear, clean complexion.

Key Ingredient Benefits • Grapefruit Peel Oil high in flavonoids and vitamin c, is an antiseptic, astringent, anti-inflammatory, soothes and tones oily acne skin • Phytic Acid is derived from the brans and hulls of most grains, beans, nuts, and seeds. Used as a skin lighting agent, phytic acid works by blocking the entrance of iron and copper in the formation of melanin to reduce inflammation and hyperpigmentation.

Key Selling Points • Antiseptic yet hydrating for excessively oily acne skin types

Ingredients: • Suppresses the bacteria that causes acne

Aqua (Water), Alcohol Denat., Hamamelis Virginiana • Mattifies and helps to control shine throughout the day (Witch Hazel) Water, Glycerin, Deoxycholic Acid, Hydrogen Peroxide, Carbomer, Lonicera Caprifolium (Honeysuckle) Flower Extract, Lonicera Japonica Personalized Prescription (Honeysuckle) Flower Extract, Xanthan Gum, Citric Acid, Aloe Barbadensis Leaf Juice Powder, Citrus Grandis (Grapefruit) Peel Oil, Phytic Acid, Vitis Vinifera (Grape) Seed • Apply under sun protection in the morning for hydration and Extract, Sodium Hyaluronate (L), oil control Potassium Sorbate, Limonene*** Presentation: • 1 oz/30 ml pump bottle Directions for Use • 1.67 oz/50 ml pump bottle Smooth onto the face and neck with finger tips until absorbed. For best results, use twice daily, morning and evening. For added protection during the day, follow with the Institut’ DERMed Brightening Moisturizer. Recommended for excessively oily skin. notes

Clarifying Peel Resurface your skin at home with the Institut’ DERMed Clarifying Peel. Formulated with oil controlling Lactic Acid and Pumpkin Enzymes this potent peel decongests clogged pores, fades skin discoloration and prevents reoccurring blemishes for a clear, clean complexion.

Key Ingredient Benefits • Pumpkin Enzymes 5% an anti-oxidant rich non-abrasive retinoic and alpha hydroxy acid exfoliator used to accelerate cell renewal, decongest clogged pores, and heal oily acne breakouts and refining the skins surface • L-Lactic Acid 5% an alternative to glycolic acid derived from sour milk that increases cellular desquamation to refine and re-texturize the skin

Key Selling Points • Accelerates the release of dead cell build-up • Decongests clogged pores • Smoothes fine lines and wrinkles

Personalized Prescription • May be used after prescribed skin polish prior to the mask Ingredients: for an intensive exfoliation Cucurbita Pepo (Pumpkin), Lanolin, Albumen, • Use in between professional treatments Lactic Acid (L), Aqua (Water), Lactobacillus/ Pumpkin Ferment Extract, Wine Extract, Glycerin, Gluconic Acid (D), Gluconolactone, Hydroxypropyl Methylcellulose, Cinnamomum Cassia (Cinnamon) Directions for Use Leaf Oil, Zingiber Officinale (Ginger) Root Oil, Eugenia Caryophyllus (Clove) Leaf Oil, Smooth a thin layer onto clean, dry facial skin with finger tips. Sodium Benzoate Avoid sensitive eye and lip areas. Leave on for three to five Presentation: minutes. Rinse thoroughly with cool water. For best results, use • 2 oz/60 ml tube once a week after cleansing. Follow with an Institut’ DERMed Clarifying Serum and Moisturizer. Apply a small amount of the Institut’ DERMed Enhancing Protective Cream for additional hydration post peel. notes

Clarifying Mask Detoxify your skin at home with the Institut’ DERMed Clarifying Mask formulated with Kaolin Clay and Tea Tree Oil to absorb oil and decongest pores for a clear, clean complexion.

Key Ingredient Benefits • Sulfur Sulfur is one of the oldest known acne treatments. Since ancient times sulfur has been used to treat skin problems such as acne, dermatitis, dandruff, rosacea and even warts. • Tea Tree Oil anti-inflammatory, antibacterial shown to be effective in controlling the edema often associated with acne, supporting cellular regeneration and wound healing • Camphor derived from the camphor tree and used for its antiseptic, soothing and purifying properties

Key Selling Points • Dries acne lesions • Accelerates healing and prevents acne breakouts Ingredients: • Inhibits bacteria Aqua (Water), Glycerin, Sulfur, Caprylic/Capric Triglyceride, Stearic Acid, Cetyl Alcohol, Kaolin, Glyceryl Stearate, Titanium Dioxide (CI 77891), Bentonite, Squalane, Personalized Prescription Xanthan Gum, Cinnamomum Camphora (Camphor) Bark Oil, Menthyl Lactate (L), Eucalyptus Globulus Leaf Extract, Gluconolactone, Melaleuca Alternifolia (Tea Tree) Leaf Oil, • Apply as a zone treatment with another mask Lonicera Caprifolium (Honeysuckle) Flower Extract, Lonicera Japonica (Honeysuckle) Flower Extract, Sodium Benzoate, • Alternate with another mask to adjust intensity of treatment Carbomer, Elaeis Guineensis (Palm) Oil, Tocopherol (D-alpha), Tocotrienols, Citrus Grandis • Apply mask to acne lesions and leave on overnight (Grapefruit) Peel Oil, Phytic Acid, Passiflora Laurifolia (Passionflower) Flower Extract, Potassium Sorbate Presentation: Directions for Use • 2 oz/60 ml tube Smooth a thin layer onto freshly exfoliated skin with finger tips. Leave on for five to ten minutes. Rinse thoroughly with cool water. For best results, use once a week. Follow with an Institut’ DERMed Clarifying Serum and Moisturizer. Apply a small amount of the Institut’ DERMed Enhancing Protective Cream for additional hydration. notes

5589 Peachtree Road Atlanta, Georgia 30341 phone 770.454.7788 • www.idermed.com © 2011 Institut’ DERMed clinical skincare Clarify Clarifying Infusion Treatment An intensive oxygenating corrective treatment combining Enzymes, Fumaric, Glycolic and Salicylic Acids, Tea Tree Oil and Hydrogen Peroxide for aggressive cellular detoxi- fication. This potent treatment may be applied for adult acne, hyperpigmentation and loss of elasticity. The Clarifying Infusion Treatment lightens, tightens, and brightens the skin for an ageless, even-toned complexion.

Key Ingredient Benefits • Step 1- Clarifying Infusion Toner includes fumaric acid, an anti-oxidant that supplies energy to the cells to produce more oxygen in the epidermis and has tissue- preserving qualities • Step 2 - Clarifying Infusion Oil includes pumpkin seed oil, a potent anti-oxidant and skin softener that helps carry active ingredients into the epidermis and eliminates cellular adhesions • Step 3 - Clarifying Infusion Mask Ingredients: includes a combination of glycolic polymer and salicylic acid CLARIFYING INFUSION TONER: used to stimulate cell turnover and suppress bacteria deep in Hamamelis Virginiana (Witch Hazel) Water, Aqua (Water), Fumaric Acid, Niacin, Camellia Sinensis the pilosetones unit accelerating skin rejuvenation and tissue Leaf Extract respiration CLARIFYING INFUSION OIL: Cucurbita Pepo (Pumpkin) Seed Oil, • Step 4 - Clarifying Infusion Serum Hemoglobin, Benzyl Alcohol includes tea tree oil derived from melaleuca leaves formulated CLARIFYING INFUSION SERUM: with a broad spectrum anti-microbial. Terpineol found in the Hamamelis Virginiana (Witch Hazel) Water, Alcohol Denat., Propolis, Glycerin, Camphor, leaves helps to reduce inflammation and edema associated Xanthan Gum, Melaleuca Alternifolia (Tea Tree) with hypersensitivity Leaf Oil CLARIFYING INFUSION MASK: Aqua (Water), Glyceryl Stearate, PEG-100 Stearate, Key Selling Points Stearic Acid, Isopropyl Palmitate, Cetyl Alcohol, Xanthan Gum, Hydrogen Peroxide, Glycerin, Salicylic Acid, • Softens and dissolves dead skin cells Glycolic Acid, Glycine Soja (Soybean) Oil, Retinyl Palmitate, Zea Mays (Corn) Oil, Eucalyptus Globulus Leaf • Purges clogged pores Oil • Oxygenates and detoxifies pores Presentation: • 2 oz/60 ml bottle • Lightens hyperpigmentation • 2 oz/60 ml bottle • 2 oz/60 ml bottle • Refines the skin texture • 2 oz/60 ml jar Personalized Prescription • Use the mask in place of a peel under steam as a peel prior to extractions • Saran wrap the mask to increase penetration • Use with steam to increase penetration • Massage mask into the skin to increase treatment intensity notes

5589 Peachtree Road Atlanta, Georgia 30341 phone 770.454.7788 • www.idermed.com © 2011 Institut’ DERMed clinical skincare Clarify Pumpkin Peel with Post Toner A potent proteolytic and keratolytic exfoliator combining enzymes and fruit acids to accelerate exfoliation without the oxidative and free radical stress associated with most peels due to its anti-oxidant benefits. The high concentration of Vitamin A in the Pumpkin Peel provides a mild retinoic acid benefit which helps mediate receptor sites responsible for cell turn over.

Key Active Ingredients • Pumpkin Peel Enzyme 15% - pH 2.46 (± 0.2) a potent botanical enzyme derived from whole pumpkin processed through a freeze drying technology that yields a natural fruit acid and enzyme concentrate used for exfoliating dead dry skin cell layers stimulating the generation of new skin cells • Pumpkin Post Toner Enzyme concentrated anti-oxidant pumpkin wine to help balance the skin’s pH and neutralize the peel activity

Key Selling Points Active Ingredients: • Softens and removes dead skin cells

PUMPKIN PEEL: • Dissolves oil residue in the pores Cucurbita Pepo (Pumpkin), Lactic Acid (L), Albumen, Lanolin, Aqua (Water), Lactobacillus/Pumpkin Ferment Extract, • Anti-oxidant to neutralize free radical reactions Wine Extract, Glycerin, Gluconic Acid, Gluconolactone, Hydroxypropyl Methylcellulose, Cinnamomum Cassia • Detoxifies congested skin (Cinnamon) Leaf Oil, Zingiber Officinale (Ginger) Root Oil, Eugenia Caryophyllus (Clove) Leaf Oil, Sodium Benzoate • Refines skin texture PUMPKIN POST TONER: Aqua (Water), Glycerin, Sucrose, Cucurbita Pepo • Lightens hyperpigmentation (Pumpkin), Alcohol Denat., Lactobacillus/Pumpkin Ferment Extract, Wine Extract, Cinnamomum Cassia (Cinnamon) Leaf Oil, Zingiber Officinale (Ginger) Root Oil, Eugenia Caryophyllus Personalized Prescription (Clove) Leaf Oil, Gluconic Acid, Yeast, Zinc Salicylate Presentation: • Apply as a zone treatment with another peel • 2 oz/60 ml jar • Use as a pre treatment for an acid peel or Microderm- • 2 oz/60 ml bottle abrasion for greater penetration

Directions for Use Apply 1 tsp of Pumpkin Peel, first to the T-zone area then clockwise (Time for 3-5 minutes DO NOT LEAVE CLIENT WHILE PEEL IS IN PROCESS). Neutralize peel with lots of cool water. Apply Pumpkin Post Toner to neutralize activity. notes

Salicylic Acid Peel 20% - pH 2.00 (± 0.2) A powerful keratolytic exfoliator derived from Wintergreen. Salicylic Acid also known as Beta-Hydroxy Acid (BHA) has a large molecular structure and works on the surface of the skin with less irritation than Glycolic Acid. The pore cleansing and antiseptic action of Salicylic Acid functions similar to Benzoyl Peroxide for sensitive skin types. It is a potent antibacterial and a very effective comedone fighting agent excellent for the treatment of acne to boost other topical correctives like Retinoids, Glycolic Acid and BPO.

Key Active Ingredients • Salicylic Acid 20% naturally occurs in wintergreen leaves, licorice, marigold, sweet birch, raspberries, willow bark and other plant sources and is used to dissolve and control oil production

Key Selling Points • Aggressively dissolves oil • Exfoliates dead skin cells • Antiseptic and antibacterial Ingredients: • Neutralizes oxidative stress Alcohol Denat., Salicylic Acid • Reduces acne inflammation Presentation: • 2 oz/60 ml bottle Personalized Prescription • Apply as a zone treatment with another peel • Use as a spot treatment • Apply as a flash or one layer leave on peel protocol

Directions for Use Apply 1 tsp of Salicylic Acid Peel, first to the T-zone area then clockwise (Time for 3-5 minutes DO NOT LEAVE CLIENT WHILE PEEL IS IN PROCESS). Neutralize peel with lots of cool water. notes