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Oct. 10, 2003 Volume 28 No. 9

Treasuring the Past Washington University in St Iouis Shaping the Future Celebratir^KQ Years Driving ability declines with age, Alzheimer's BY GILA Z. RECKESS More on Page 3 In one of the first studies to track Alzheimer's research at WUSTL leads driving performance over time to better treatment of the disease. in older adults, University re- searchers found driving abilities predictably worsen in individuals Alzheimer's disease is the most with early Alzheimer's disease and common cause of dementia in to a lesser extent, in older adults older adults and affects about 4.5 without dementia. million Americans. Affected indi- The findings appear in the viduals experience memory diffi- October issue of the culties and problems with Journal of the American attention and eventually Geriatrics Society. lose the ability to perform "As we expected, peo- complicated tasks such as ple with dementia, gener- driving. ally in the mild stages, But according to co- declined faster than the author John C. Morris, nondemented individu- M.D., principal investiga- als," said senior author tor of the Alzheimer's Janet M. Duchek, Ph.D., Disease Research Center associate professor of psy- Morris and the Harvey A. and chology and of occupa- Dorismae Hacker Fried- tional therapy. "But it is very man Distinguished Professor of interesting that there also was a Neurology, it's impossible to pre- decline in some of our nonde- dict driving performance based Graduate students Huping Luo (left) and Shaibal Roy flank Milorad P. Dudukovic, Ph.D., the Laura and mented participants. This is a pre- solely on whether a person has William Jens Professor of Environmental Engineering and chair of chemical engineering, as they view liminary study, but it suggests test- been diagnosed with dementia. catalyst particle motion in a slurry system in the Chemical Reaction Engineering Laboratory. Dudukovic ing individuals with mild demen- That's why the research team, is an associate director of the new multi-institutional Center for Environmentally Beneficial Catalysis. tia every six months can be useful which also included Linda Hunt, to identify those who become Ph.D., formerly at the School of unsafe." See Driving, Page 3 WUSTL joins new center; goal is to develop environmentally friendly chemical processes

BY TONY FITZPATRICK liam Jens Professor of Envi-ron- mental Engineering and chair of Washington University is "Participation in this the Department of Chemical joining two other universi- center ... will help us Engineering at Washington Uni- ties in forming a new cen- versity; and John P.N. Rosazza, ter devoted to developing the and our collaborators Ph.D., professor and head of basis for environmentally friendly truly abide by the medicinal and natural product chemical processes. chemistry at Iowa. The National Science Foun- principles of green A major thrust of the NSF and dation (NSF) has announced that chemistry and green the CEBC is the development of the Center for Environmentally "green" chemistry techniques and Beneficial Catalysis (CEBC) has engineering to make the application of green engineer- been selected to receive $17 mil- these chemicals ing principles that will enable the lion under the NSF Engineering $340 billion-per-year chemical Research Center (ERC) program. in a clean way." industry to whittle costs to keep Additional funding streams MILORAD P. DUDUKOVIC the environment clean, estimated and donated facilities as a result at approximately $10 billion of the award are expected to per year. bring the total package value to implement them in practice. "The School of Engineering & Faculty achievement Lee Epstein, Ph.D. (left), and Eugene nearly $30 million. The CEBC director is Bala Applied Science at Washington M. Johnson Jr., Ph.D., greet each other at the Faculty The CEBC is a multidiscipli- Subramaniam, Ph.D., the Dan F. University is delighted to be a Achievement Awards Ceremony Sept. 30 at the Eric P. Newman part of the team which has been Education Center on the Medical Campus. Epstein, the Edward nary, multi-university research Servey Distinguished Professor in Mallinckrodt Distinguished University Professor of Political center led by the University of chemical and petroleum engineer- awarded an engineering research Science in Arts & Sciences and professor of law in the School Kansas, with the University of ing at Kansas. The deputy director center from the National Science of Law, was recognized with the Arthur Holly Compton Faculty Iowa and Washington University is Daryle H. Busch, Ph.D., the Roy Foundation," said Christopher I. Achievement Award. Johnson, the Norman J. Stupp Professor serving as core partners. Its mis- A. Roberts Distinguished Professor Byrnes, Ph.D., the Edward H. and of Neurology and professor of molecular biology and pharma- sion is to develop chemical of Chemistry at Kansas. Florence G. Skinner Professor in cology and co-director of the Alzheimer's Disease Research processes that are environmental- Serving as CEBC associate Systems Science and Mathematics Center in the School of Medicine, was honored with the Carl ly friendly as well as economically directors are Milorad P. Duduk- and dean of the engineering and Gerty Cori Faculty Achievement Award. viable, and incite industry to ovic, Ph.D., the Laura and Wil- See Center, Page 6 Metzidakises are newest faculty family This Week In WUSTL History Oct. 12,1973 BY NEIL SCHOENHERR sity's invitation to live rent-free on care of our daily needs. Oct. 11,1858 campus for three years since the "It's been a wonderful experi- The Board of Directors approved a res- The Samuel B. and Charles B. Edison The residents of Park/Mudd faculty family program was start- ence so far." olution creating the office of chancellor. Theatre was dedicated. Residential College might ed in 1998. Metzidakis, who moved into notice some changes happening Officially, their role is to his new apartment in Park/Mudd Oct. 11,1992 Oct. 12,1993 in their dorm this year — talent integrate academic and residen- in July, sees his role as helping WUSTL hosted the first debate of the Douglass C. North, Ph.D., the Spencer shows, jazz music, films. tial life. add a faculty presence to everyday presidential campaign, featuring T. Olin Professor in Arts & Sciences, It's all part of Stamos Metzi- "When this idea was proposed residential life. President George H.W. Bush, Arkansas was awarded the Nobel Memorial Prize dakis' plan to bring a faculty pres- to me, I thought it was something "I think we are there to show Gov. Bill Clinton and W. Ross Perot. in Economic Sciences. ence to the residential college and I just couldn't pass up," said the students, more than anything, have a little fun in the process. Metzidakis, Ph.D., professor of that professors are real people Oct. 12,1962 This feature will be included in each Metzidakis and his wife, Sarah, French and of comparative litera- and that they have a life, that they 2003-04 issue of the Record Thomas H. Eliot was inaugurated as are the newest faculty family liv- ture, both in Arts & Sciences. in observance of Washington are not only people who walk in the 12th chancellor, serving until 1971. ing in the South 40. They are the "The whole staff has beer) so help- and out of a classroom," he said. University's 150th anniversary. fifth family to accept the Univer- ful getting us settled and taking See Family, Page 6 2 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS Grad student leaders to meet here Oct. 10-12

BY SUSAN KILLENBERG MCGINN Berland said the conference builds on the University's tradi- Graduate student leaders tion of encouraging graduate- from across the country student leadership and shared will gather at the Univer- governance. sity Oct. 10-12 to exchange "The graduate student com- ideas about what they think are munity here is fortunate that the the key issues in graduate edu- University values shared gover- cation in the 21st century. nance — where graduate stu- The National Conference on dents actively participate in the Graduate Student Leadership, administrative activities of the part of the University's 150th University and have the oppor- anniversary celebration, will tunity not only to contribute, bring to campus 42 graduate but also to gain the experience student delegates from the 14 that these leadership opportuni- universities in the Woodrow ties provide," said Christina Wilson National Fellowship Linsenmeyer, a doctoral student Foundation's "Responsive in music in the Graduate School Ph.D." program. of Arts & Sciences, who will The conference will feature serve as the student editor of the six panel discussions Oct. 11. printed conference proceedings. "The theme for each panel Robert Weisbuch, Ph.D., was chosen by the delegates president of the Woodrow Cafe United Way (From left) Kalyn Coppedge, second-year student in the George Warren themselves, and they include Wilson National Fellowship Brown School of Social Work, shows off some of the baskets and bags of treats that were up for such important issues as gradu- Foundation, agreed. The foun- raffle to United Way representatives Lottie Wade and Fannie Robinson at GWB's Cafe United Way and United Way Rally Raffle Oct. 1 in Goldfarb Hall. GWB students, faculty and staff were able to ate students building a sense of dation, which is providing sup- purchase lunch and buy raffle tickets for various prize baskets. All proceeds were donated to the community within their port for the conference, selected United Way. schools, mentoring and inter- Washington University in 2001 disciplinary training, and the as one of three universities to social responsibility of scholars inaugurate its "Responsive to the world outside of acad- Ph.D." initiative aimed at eme," said Robert E. Thach, improving doctoral education 'Give Thanks Give Back' is chance to help in the United States. Ph.D., dean of the Graduate BY NEIL SCHOENHERR adopted that year, the largest sin- or groups can join together to School of Arts & Sciences and "Washington University, with gle contribution in the cam- adopt an entire family. When you the conference convener. its graduate Dean Bob Thach, In honor of the Sesquicentennial paign's history. sign up, you will be given clothing The panel discussions, which has taken a national leadership celebration, organizers of the "The beauty of Give Thanks and shoe sizes for each person as are free and open to University role in improving doctoral edu- United Way's annual "Give Give Back is that everyone can be well as a list of items they have graduate and professional stu- cation," Weisbuch said. "This Thanks Give Back" holiday gift involved," said Tabitha Knerr, requested. dents, will be held from 9 a.m.- conference for student leader- drive are hoping the University assistant coordinator of commu- Individuals can sign up in 5:15 p.m. in the auditorium of ship is crucial, for it engages the community adopts 150 families nity service. "You can organize Mallinckrodt and Wohl student Uncas A. Whitaker Hall for next generation of intellectual this year. your office to adopt a family; you centers Oct. 27-Nov. 7. Groups Biomedical Engineering. A leaders in the challenge. These The Office of Student Activ- can make a tax-deductible dona- can e-mail [email protected] breakfast before and a reception are the individuals who will ities began this support of the tion; you can donate (brand new) to get started. after the panel sessions will pro- determine the nature of acade- 100 Neediest Cases in 1998, when clothes, or shoes or toys; you can Gifts will be collected Nov. 10- vide graduate-professional stu- mia and its power to improve staff members adopted a single bring your friends and family to a 14, followed by volunteer gift- dents and administrators from the human condition beyond family through the Give Thanks gift-wrapping party. wrapping parties Nov. 15 and 22. their schools an opportunity for academia." Give Back campaign. "Each of us has something Monetary donations are welcome informal discussions with the Both Weisbuch and By 2001, the effort had to give." as well. delegates, including three from Chancellor Mark S. Wrighton evolved into a campus-wide pro- Individuals can adopt one For more information, call Washington University. will speak at the conference. gram. Eighty-three families were member of a family on their own 935-9659. "This is a unique opportuni- The three student delegates ty to hear what graduate and representing Washington Uni- professional student leaders versity at the conference are think are the perplexing chal- Aline Boos, a doctoral student Court of appeals lenges and promising practices in biology and biomedical sci- PICTURING OUR PAST in graduate education in the ences; Julie H. Gabel, a third- 21st century," said Elaine P. year law student; and Scott A. session at law Berland, Ph.D., associate dean Hendrickson, a doctoral student in the graduate school and co- in political science in Arts & school Oct. 15 conference director with Nancy Sciences. P. Pope, Ph.D., assistant dean in For more information, call BY JESSICA MARTIN the school. 935-7355. The Missouri Court of Ap- peals Eastern District will hold a special session from Atlantic Monthly ranks WUSTLNo. 11 9:30 a.m.-noon Oct. 15 in the School of Law's Bryan Cave BY NEIL SCHOENHERR Moot Courtroom in Anheuser- The Atlantic's top 25 Busch Hall. The Atlantic Monthly magazine The public is invited to hear has created its first ranking of The Atlantic Monthy's top 25 cases focusing on whether a all types of colleges and universi- institutions are: victim's unborn child is con- ties, and Washington University is l.MIT sidered a "person" in a murder rated 11th in the nation. 2. Princeton case; a utility company's lia- The top 10 schools in order 3. Cal Tech bility in a car accident case are: the Massachusetts Institute of 4. Yale involving live electrical wires; Technology, Princeton University, 5. Harvard the statute of limitations in the California Institute of Techno- a wrongful death case; and 6. Stanford logy, Yale University, Harvard due process in a drug convic- University, Stanford University, 7. Columbia tion case. Columbia University, the Univer- 8. Penn The court periodically holds sity of Pennsylvania, Brown Uni- 9. Brown sessions in law schools as part versity and Swarthmore College. 10. Swarthmore of an educational program. "This review of colleges and 11. Washington University The panel of judges hearing universities is yet another illustra- 12. Amherst oral arguments are Sherri B. tion of our attractiveness to tal- 13. UC Berkeley Sullivan, chief judge; Kathianne ented students," Chancellor Mark 4VVERi/^ Knaup Crane; Mary K. Hoff; 14. Duke Democratic Rep. Melvin Price (seated), who S. Wrighton said. "We must sus- % and Glenn A. Norton. 15. Dartmouth served Illinois from 1945-1988, visits the tain our effort to be a student- After the special session, the 16. Pomona University's computer center in November focused university, with the 1958. Some of the equipment in the center had 150 judges will be available to strongest possible faculty to 17. UCLA been used to track orbits of the Russian years answer general procedural engage our students in the best 18. Rice Sputnik satellites. With Price are (from left) questions from the audience. research and educational pro- 19. Williams Edwin Roth, cartographer and astronomer; Treasuring the Past To limit the amount of dis- Shaping the Future grams." 20. Georgetown Robert Carty, technical supervisor; and Harvey turbances to the proceedings, The ranking was derived from 21. Cornell Cohn, director of the computer center. The use of computers visitors are asked to enter and three variables reported by each 22. Claremont McKenna has increased exponentially over the years. The most recent exit the courtroom only during institution: admission rate, SAT example of this at the University is the Arc Technology Center breaks between each attorney's 23. Harvey Mudd scores and rank in high-school at Olin Library, where students, faculty and staff can digitize oral argument. class. This is the first time The 24. William and Mary and edit images, text, slides and videotape; prepare interactive Case briefs for the oral Atlantic has published the study. 25. Middlebury tutorials and course modules; and develop multimedia with argument session will be on The November issue also car- sound, video, animation, images and text. temporary reserve in the law ries articles on existing rankings, be ranked in the top 25. North- school's library under "Eighth such as the U.S. News & World western University and the Washington University is celebrating its 150th anniversary in 2003-04. Special Circuit Special Session." Report rankings. University of Notre Dame ranked programs and announcements will be made throughout the yearlong observance. For more information, call Washington University is the 26 and 31, respectively, while the *35-6430 or go online to only institution in the Midwest to University of Chicago ranked 39. law.wustl.edu. record.wustl.edu WASHINGTON UNIVERSITY IN ST. LOUIS Oct. 10,2003 3 School of Medicine Update Advances in Alzheimer's University research leads to better treatment of the disease

happened as patients were first showing symptoms of Key brain structure Alzheimer's disease, so that provides strong evidence the shape changes we observed in changes over time the hippocampus may be actu- ally causing at least some of the symptoms of Alzheimer's BY JIM DRYDEN aging. Because learning and mem- disease." ory are greatly affected by Alzheimer's disease also By the time a person begins Alzheimer's disease, the team causes volume changes, which to experience symptoms focused on a structure important can be difficult to interpret of Alzheimer's disease, for learning and memory: the because people of various sizes several brain structures already hippocampus, a seahorse-shaped tend to have different sized ■ are dotted with the plaques and structure deep inside the brain. brains. By using imaging scans tangles that characterize the ill- The researchers compared to measure subtle changes in ness. Research teams are work- healthy people with those in the shape, the researchers believe ing to identify changes in brain early stages of Alzheimer's disease. they have a more sensitive indi- structures as early as possible To identify differences, they con- cator of the presence of disease. in the course of the disease — ducted magnetic resonance imag- "Tangles and plaques occur at a time when it might soon ing scans two years apart on 18 early in a part of the hippo- be possible to halt its progress patients with mild Alzheimer's campus called the CA1 region before people become severely disease and 26 healthy individuals John G. Csernansky, M.D. (right), shows a brain image to Lei Wang, and in another sub-field of the impaired. about the same age. Ph.D., and Deanna M. Barch, Ph.D., in the Silvio Conte Center for hippocampus called the A team of neuroscientists at The team measured differences Neuroscience Research. subiculum," Wang said. "In our the Silvio Conte Center for in the volume and shape of the study, we were able to see Neuroscience Research and the hippocampus and the differences "There were changes in normal autism, researchers believe differ- changes occurring in those Alzheimer's Disease Research in the way the volume and shape people, too," Wang said, "but the ences in the shape of various same sub-fields as the disease Center at the University are became more abnormal over time. changes were more pronounced in brain structures probably show progressed over time. Our working with state-of-the-art In people without Alzheimer's people with mild Alzheimer's dis- up very early — perhaps even at findings seem to correspond to imaging techniques to see disease, hippocampal volume ease. At the start of the study, there birth. what others have found in whether they can identify sub- decreased by about 4 percent over were some differences between the "But in Alzheimer's disease, post-mortem studies." tle changes in brain structures two years. But in people with two groups, but at the two-year presumably brain structures have The ultimate goal is to iden- that are present in the earliest early Alzheimer's disease, volume follow-up, the changes had spread a normal size and shape until the tify shape and volume differ- stages of the disease. decreased by 10 percent. to a wider region of the hippo- disease cascade begins," said John ences that can predict the Reporting online and in an In addition, the changes in campus in people with Alzheimer's G. Csernansky, M.D., the future onset of the disease. upcoming issue of the journal shape in healthy people tended to disease." Gregory B. Couch Professor of Detecting the disease before Neurolmage, Lei Wang, Ph.D., be confined to a small part of the Much of the Conte center's Psychiatry and director of the clinical symptoms appear will research associate in psychiatry, structure. But in Alzheimer's research uses imaging to try to Conte Center. "Changes in hip- be critical when treatments and his colleagues have identi- patients, shape changes involved identify subtle anatomical differ- pocampal shape represent early become available to prevent fied changes in the brain that larger parts of the hippocampus, ences that demonstrate a person is evidence of damage to a part of more extensive damage and appear to distinguish Alz- including an area where plaques at risk for a particular disease. In the brain that previously was halt the progression of the heimer's disease from healthy and tangles are known to appear. diseases like schizophrenia or normal. Those changes in shape disease. New technique offers dynamic study of proteins

BY GILA Z. RECKESS interstitial fluid, so you'd expect the animals with a drug called a and young mice was not signif- the two compartments to com- gamma-secretase inhibitor, icantly different, which may School of Medicine research- municate," Cirrito said. "We which drastically decreases pro- suggest that another, previously ers in collaboration with were surprised to find they were duction of ABeta and currently unidentified mechanism is researchers at Eli Lilly and Co. not correlated in young mice. is being investigated as a poten- involved in the development of have developed a new tech- There apparently is a shift dur- tial therapy for humans with the Alzheimer's plaques. nique that dynamically studies ing aging and/or during plaque disease. "The difference in the elimi- proteins in the fluid between development that affects how Ten more interstitial fluid nation rate may turn out to be brain cells, called interstitial ABeta is moved between the two samples were collected over the an extremely important find- fluid, known to be related to Cirrito Holtzman compartments because levels of following 10 hours to measure ing," Holtzman said. "This sug- Alzheimer's disease. ABeta do correlate in older, how quickly the ABeta that had gests that once plaques form, Using this new technique in of Neurology and a professor plaque-ridden mice." accumulated before the injec- they alter the metabolism of mice, the team discovered the of molecular biology and phar- Because microdialysis is per- tion was broken down. ABeta in the brain in a very relationship between levels of a macology. formed in living animals, the The team found it takes specific way. key molecule involved in A key step in the development team took multiple samples about twice as long for the This finding and technique Alzheimer's disease, called of Alzheimer's disease is the for- from each animal to study the soluble pool of brain ABeta should assist us in determining amyloid-beta (ABeta), changes mation of sticky, senile plaques breakdown and accumulation of to breakdown in mice with how other molecules involved in interstitial fluid and cere- in the brain, composed primarily ABeta over time. Alzheimer's-like brain plaques in ABeta metabolism influence brospinal fluid as the disease of clumps of ABeta. Although The team first measured than in young mice without Alzheimer's disease as well as progresses. Cerebrospinal fluid, these plaques are believed to interstitial fluid ABeta levels plaques. be useful in developing new the fluid that cushions and form at least in part in the spaces every hour for eight hours. However, the baseline diagnostic and treatment surrounds the brain, is a main between brain cells, there previ- The researchers then injected concentration of ABeta in old strategies." focus in diagnosing and pos- ously was no way to selectively sibly treating Alzheimer's extract and measure levels of disease. ABeta in interstitial fluid. of individuals with mild Alz- "While the majority of the "We now have a way to The main obstacle to studying heimer's disease failed the driving nondemented people we tested measure a pool of ABeta that ABeta in interstitial fluid is that Driving test, compared with only 14 per- remained very safe drivers, as previously could not be evalu- the molecule is larger than those Study: Increased age alone cent of those with very mild we followed them, more and ated," said graduate student typically measured with micro- dementia and 3 percent of non- more became unsafe," Morris John R. Cirrito. "Using this dialysis. The ABeta molecules appears to be a risk factor demented participants. said. "Age-related changes other new approach, we were able to also tend to be sticky, making the - from Page 1 The current study details lon- than dementia likely contribute identify another difference process even more difficult. gitudinal findings with the same to driving performance and between young mice that have Cirrito and his colleagues Medicine and now at Flathead group of participants. The team should be further investigated not yet developed Alzheimer's- therefore developed a unique Valley Community College, and administered the road test every in larger groups of older like changes and those that way to perform microdialysis, David B. Carr, M.D., associate pro- six months to the individuals adults." have developed Alzheimer's- incorporating two key compo- fessor of medicine, developed an who passed the test the first time Signs that should raise con- like brain changes, which pro- nents: a membrane that captures extensive, 45-minute, in-traffic and then compared the time it cern include an inability to vides a new opportunity to larger molecules and proteins driving test called the Washington took each group to go from pass maintain speed or to stay in one explore the development of that make ABeta less sticky. University Road Test. to fail. lane while driving, hesitating at this disease." Armed with this new method, "Appropriate testing is impor- As expected, the mild Alz- turns or becoming lost, particu- Cirrito is first author of the the team confirmed that in cere- tant," Morris said. "For individuals heimer's group declined the larly in familiar areas. study, published in the Oct. 1 brospinal fluid, ABeta42 levels who still drive safely, it can be fastest, followed by the very mild "One of the features of issue of The Journal of decrease as the disease progress- reassuring and help them remain dementia group. Surprisingly, dementia is that individuals lose Neuroscience. The principal es, whereas ABeta40 remains independent. It also can be used to performance in the non-dementia insight and may not recognize investigator is David M. unchanged. Surprisingly, they follow individuals to detect the group also declined over time, that they are becoming unsafe," Holtzman, M.D., the Andrew discovered a different pattern in development of unsafe driving though at a slower rate than the Morris said. "We must increase B. and Gretchen P. Jones interstitial fluid: ABeta42 behaviors and intervene, hopefully other two groups. public awareness about driving Professor of Neurology and remains constant while ABeta40 before there is an actual crash or In addition, when data from all issues in demented persons and head of the Department of increases. other problem." three groups was combined, in- empower families and health Neurology, the Charlotte and "ABeta that ends up in the In a study published by Hunt creased age alone appeared to be a care professionals to intervene Paul Hagemann Professor cerebrospinal fluid comes from and the team in 1997, 41 percent risk factor in driving performance. before a tragedy occurs." 4 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS University Events Assembly Series welcomes Brenner, Gomes Oct. 14-15

BY NADEE GUNASENA focus on what he considers the AND BARBARA REA important things in life, empha- sizing the need for distinguishing The Assembly Series is bring- between the "plausible lies" that ing two speakers on consecu- our society defines as "the good tive days to Graham Chapel. life" and the "fantastic truths" that Nobel Prize-winning biologist he believes can bring real and last- Sydney Brenner will talk at 4 p.m. ing happiness. Oct. 14, and the chaplain of Har- Gomes has written a number vard University, the Rev. Peter J. of other books, including the Gomes, will speak at 11 a.m. the best-selling The Good Book: following day. 1986, he served as director of the is coded by a triplet of RNA. Minister of The Memorial Reading the Bible With Mind and Brenner's talk, "Humanity's Medical Research Council His work-in genetics and at Church for nearly as long. Heart, and Sermons: Biblical Genes," will be the annual Arthur Laboratory of Molecular Biology the molecular level has led to Ordained to the American Wisdom for Daily Living. Gomes Holly Compton Memorial at Cambridge University. major gains in understanding a Baptist Ministry in 1968, has also published several vol- Lecture. He is now a distinguished pro- range of afflictions, including Gomes is widely regarded as umes of sermons, as well as arti- Brenner has made numerous fessor at the Salk Institute of cancer, AIDS, strokes and neu- one of America's most distin- cles and essays. contributions to the fields of Biological Studies in La Jolla, rodegenerative diseases. guished preachers. In 1999, he Gomes has received numerous genetics and biology. In 2002, he Calif. He also serves as president Brenner's lecture will discuss was included in Talk magazine's honors, including many honorary won the Nobel Prize in physiolo- of the Molecular Sciences some of the questions raised by feature on "The Best Talkers in degrees and being named an hon- gy or medicine for his research Institute in La Jolla and Berkeley, the completion of the Human America: Fifty Big Mouths We orary fellow of Emmanuel College on the nematode roundworm Calif., a private institute he Genome Project. He will talk Hope Will Never Shut Up." at the University of Cambridge, C. elegans. founded in 1996 to advance inter- about both the benefits and the Gomes was chosen to partic- where the Gomes Lectureship has His work paved the way disciplinary research in fields fears brought on by recent break- ipate in the presidential inaugu- been established. toward the first genetic mapping such as genomics, genetics and throughs in genetic research, and rations of Ronald Reagan and In 2001, he received Harvard's of a multicellular organism and computational biology. his belief that the brain is mighti- George HW. Bush. Phi Beta Kappa Award. He also was a significant factor in the Brenner has been a part of er than the genome. The Good Life, published in holds the position of trustee of development of the Human many landmark scientific discov- Gomes' talk will be based on 2002, addresses the challenges the Museum of Fine Arts in Genome Project. His achieve- eries over the years. He was his most recent book, The Good and importance of living Boston. ments with C. elegans are now among the first to view Watson Life: Truths That Last in Times of responsibly. Gomes debunks the He graduated from Bates Col- considered a research standard and Crick's model for the DNA Need, and is sponsored by the idea that today's college stu- lege in 1965 and Harvard Divinity worldwide for developmental double-helix structure. Campus Y. dents are spoiled, materialistic School in. 1968. biology. Brenner and his colleagues Gomes has served in The and morally complacent and All Assembly Series lectures are Born and raised in South discovered messenger RNA, Memorial Church at Harvard for believes they have the moral free and open to the public. For Africa, Brenner was educated at which can be translated into pro- more than 30 years and has been curiosity to search for the more information, call 935-4620 Oxford and Cambridge universi- teins. Working with Crick, he also the Plummer Professor of truths. or go online to wupa.wustl.edu/ ties in the 1950s. From 1979- proposed that a single amino acid Christian Morals and the Pusey He offers advice on how to assembly. Lone Star* Homecoming Football Game • Blood Drive

"University Events" lists a portion of the prof, of medicine and of cell biology & Needleman Library. 362-0183. 4-5 p.m. Biochemistry & Molecular Defects in Cell-cell Junction Proteins." activities taking place at Washington physiology. McDonnell Medical Sciences Jeffrey E. Satfitz, prof, of pathology & Noon. Neurology & Neurosurgery/CSNSI Biophysics Seminar. "Piezoelectric University Oct. 10-23. Visit the Web for Bldg., Rm. 426. 362-3964. Seminar. Elias Aizenman, prof, of neurobi- Membrane-based Motors in the Outer immunology. McDonnell Medical Sciences expanded calendars for the Hilltop Campus Noon-5 p.m. Ophthalmology & Visual ology, U. of Pittsburgh. Maternity Bldg., Hair Cell." William Brownell, prof, of Bldg., Rm. 426. 362-3964. (calendar.wustl.edu) and the School of otorhinolaryngology & communicative Sciences Lecture. Annual David & Mary Schwarz Aud. 362-9462. 1:30-3 p.m. Film & Media Studies Medicine (medschool.wustl.edu/ Seslen Lecture. "Restoring Vision with sciences, Baylor College of Medicine. Cori Noon-1 p.m. Work, Families & Public Lecture. "I Love Lucy, Everybody Else calendars.html). Microelectronic Retinal Implant (Artificial Aud., 4565 McKinley Ave. 362-0261. Policy Seminar Series. "No Exit: What Loves Raymond." Richard Chapman, sen- Vision)." Mark S. Humayun, prof, of oph- Parents Owe Children and What Society 4 p.m. Infectious Diseases Seminar. Carl ior lecturer in screenwriting. Co-spon- thalmology and biomedical engineering, U. Owes Parents." Anne Alstott, prof, of law, G. Harford, M.D., Visiting Professorship sored by American Culture Studies. of S. Calif. Eric P. Newman Education Yale U. Eliot Hall, Rm. 300. 935-4918. of Infectious Diseases Research Seminar. Brown Hall, Rm. 118. 935-4056. Exhibits Center. 362-5722. "Molecular Mechanisms by Which 3 p.m. Neuro-oncology Research Group 4 p.m. Anatomy & Neurobiology Seminar. 1 p.m.-5 p.m. Neuroradiology CME Course. Epstein-Barr Virus Alters Cell Growth and Seminar Series. "Modeling Cancer and "Seeing in 3D: Contributions of Visual History of Adult Education at "International Symposium on CT and MR Survival; Targets for Therapeutic Cancer Genomes in the Mouse." Ronald A. Area MT to Stereoscopic Depth Per- Washington University, 1854- Brain Perfusion." Colin P. Derdeyn, assoc. Intervention." Elliot Kieff, Albee Professor DePinho, prof, of medicine and genetics, ception." Greg DeAngelis, asst. prof, of 2004. Through May 31. January prof, of radiology, neurology and neuro- of Medicine, Microbiology & Molecular Dana-Farber Cancer Inst, Harvard U. anatomy & neurobiology. McDonnell Hall, Rm. 20. 935-4806. surgery, course chair. (Also 7:30 a.m.-noon Genetics, Harvard U. McDonnell Pediatric McDonnell Medical Sciences Bldg., Rm. Medical Sciences Bldg., Rm. 928. Oct. 11 and 8 a.m.-noon Oct. 12.) Cost: Research Bldg., Rm. 8101. 362-1514. Influence 150:150 Years of 928. 747-0407. 362-7043. $250. Eric P. Newman Education Center. To Shaping a City, a Nation, the 7 p.m. Donald Danforth Plant Science World. Through Dec. 7. Gallery of register: 362-6891. 4 p.m. Biology Seminar. "The Mammalian Thursday, Oct. 16 Auditory System: Corticofugal Feedback Center Symposium. Annual Fall Art. 935-4523. 4 p.m. Medicine Lecture. Annual Carl and Plasticity." Nobuo Suga, prof, of biolo- 8 a.m. Department of Medicine Grand Symposium. "Mechanisms of Disease Moore Memorial Lecture. "New Paradigms Inscriptions of Time/Topographies gy. Rebstock Hall, Rm. 322. 935-6850. Rounds. Carl G. Harford, M.D., Visiting Resistance and Susceptibility." (Continues , of History: The Photographs of From Leukemias." Janet Rowley, prof, of Professorship of Infectious Diseases 8:30 a.m.-5:30 p.m. Oct. 18.) Donald Alan Cohen. Through Dec. 7. medicine, molecular genetics, cell biology 4 p.m. Chemistry Seminar Series. Rounds. "Epstein-Barr Virus and Human Danforth Plant Science Center, 945 N. Gallery of Art. 935-5423. and human genetics, U. of Chicago. Moore "Supramolecular Chemistry With a View Malignancies: A Paradigm in Viral Warson Road. 935-6860. Aud., 660 S. Euclid Ave. 362-8801. Towards Biology and Medicine." Steven L. Oncology." Elliot Kieff, Albee Professor of 7:30 p.m. Diversity Programs Lecture. Matthew Carter Exhibit. Oct. 9-Nov. 28. Regan, prof, of chemistry, Lehigh U. South Medicine, Microbiology & Molecular 4 p.m. Anatomy & Neurology Departmental Annual Homer G. Phillips Lecture Series. (Opening reception 6-8 p.m. Oct. 10.) Bldg., Rm. 3907, Philip Needleman Library. Genetics, Harvard U. Wohl Clinic, Malvern Seminar. "Optical and Genetic Approaches Vanessa Northington Gamble, assoc. prof, Des Lee Gallery, 1627 Washington Ave. 935-6530. B. Clopton Amphitheatre. 362-1514. 621-8735. Toward Understanding Neuronal Circuits in of health policy and management, Johns Zebrafish." Joseph Fetcho, dept. of neuro- 4 p.m. Physics Seminar. "Magnetic Noon. Genetics Seminar Series. Hopkins U. (5:30 p.m. cocktails, 6:30 p.m. New Beginnings: The First Decade of the biology & behavior, State U. of N.Y., Stony Resonance Using Polarized Muons: "Measures of Linkage Disequilibrium." dinner.) Eric P. Newman Education Center. Washington University Medical Brook. McDonnell Medical Sciences Bldg., Principles and Applications." Emil Roduner, John Rice, prof, of mathematics in psy- To register, call 362-6854. | Campus, 1915-1925. Through May Rm. 928. 362-7043. Inst. of Physical Chemistry, U. of Stuttgart, chiatry. McDonnell Medical Sciences 31. Glaser Gallery, Becker Medical Germany. (3:45 p.m. coffee.) Compton 7 p.m. Gallery of Art Friday Forum. Bldg., Rm. 823. 362-2139. Library, 7th Fl. 362-4236. Hall, Rm. 241.935-6276. Saturday, Oct. 18 "Collecting Patterns: The History of the 4 p.m. Chemistry Seminar Series. 7:30 a.m.-12:15 p.m. Cardiology CME Washington University Gallery of Art." 6 p.m. Architecture Monday Night Lecture "Bioimaging With Mass Spectrometry." Course. "Practical Management of Mark Weil, dir., and Sabine Eckmann, cura- Series. "Material Design." Marco Nicholas Winograd, Evan Pugh Professor Arrhythmias." Michael E. Cain, T&H Lewin tor, Gallery of Art. (6:30 p.m. reception.) Steinberg, asst. prof, of architecture, of Chemistry, Penn. State U. McMillen Professor of Cardiovascular Disease in Film Cost: $10, $5 for students. Gallery of Art. Harvard U. Graduate School of Design. Lab., Rm. 311.935-6530. 935-4523. (5:30 p.m. reception, Givens Hall.) Medicine, and Mitchell N. Faddis, asst. Steinberg Hall Aud. 935-6200. 4 p.m. Religious Studies Lecture. E.G. prof, of medicine, co-chairs. Cost: $55. Friday, Oct. 17 Welth Lecture. "When Is a Text About a Eric P. Newman Education Center. To reg- ister, call 362-6891. 7 p.m. Gallery of Art Presentation. Lone Saturday, Oct. 11 Woman a Text About a Woman: Dilemmas Tuesday, Oct. 14 of a Feminist Historian of Women's Star. John Sayles, dir. Opening remarks 8 a.m.-3 p.m. Ophthalmology Fall Update. 10 a.m. Physics Science Saturdays Religions in the Greco-Roman by Lutz Koepnick, prof, of Germanic lan- Paul F. Palmberg, prof, of ophthalmology, Noon. Molecular Microbiology & Microbial Lecture Series. "Biophysics of Cell Mediterranean." Ross S. Kraemer, prof, of guages and literatures and of Film & U. of Miami, guest speaker. James E. Pathogenesis Seminar Series. "Early Motion." Anders Carlsson, prof, of religious studies, Brown U. Women's Media Studies. Gallery of Art. 935-5423. Standefer, clinical prof, of ophthalmology, Events in the HIV-1 Replication Cycle." Lee physics. Crow Hall, Rm. 201. 935-6276. U. of Minn., WUSTL Ophthalmology Ratner, prof, of internal medicine. Cori Bldg., Formal Lounge. 935-7762. Distinguished Alumni Lecturer. Cost: $100 Aud., 4565 McKinley Ave. 747-2132. 4-5 p.m. Ophthalmology & Visual for ophthalmologists & optometrists, $30 Monday, Oct. 20 4 p.m. Assembly Series. Arthur Holly Sciences Seminar Series. "Neural for physicians in training. Eric P. Newman Compton Lecture. "Humanity's Genes." Development in Cross-eyed Infants: The 4 p.m. Biology Seminar. "Models of Lectures Education Center. To register, call Sympatric Speciation: Facts and Sydney Brenner, Distinguished Research Role of Correlated Visual Cortex Inputs." 362-5722. Professor, the Salk Inst, 2002 Nobel laure- Lawrence Tychsen, prof, of ophthalmolo- Generalizations." Sergey Gavrilets, prof, of Friday, Oct. 10 10 a.m. Physics Science Saturdays Lecture ate. Graham Chapel. 935-5285. gy & visual sciences, pediatrics, and of ecology & evolutionary biology and of Series. "The Microscopic Study of Dust anatomy & neurobiology. Maternity Bldg., mathematics, U. of Tenn. Rebstock Hall, 9:15 a.m. Pediatrics Grand Rounds. 4 p.m. Center for the Humanities Writers From Stars." Tom Bernatowicz, prof, of Rm. 725. 362-1006. Rm. 322. 935-6706. Annual J. Neal & Lois Middelkamp Series Seminar. Terry Teachout, author. physics. Crow Hall, Rm. 201. 935-6276. Lecture. "Smallpox, Smallpox Vaccine McMillan Hal, Rm. 115, McMillan Cafe. 4 p.m. University Libraries Our Favorite 5:30 p.m. Radiology Lecture. Annual and Bioterrorism Preparedness." John F. 1 p.m. Joint Center for East Asian Studies 935-5576. Books Lecture Series. "Hector Berlioz Wendell G. Scott Memorial Lecture. Modlin, prof, and chair of pediatrics and Symposium. "East Asian Cinema and the (1803-1869): Sources and Documents." "Imaging of Abdominal Lymph Nodes prof, of medicine, Dartmouth Medical Globalization of Culture." Robert Chi, asst. Hugh MacDonald, Avis H. Blewett From LAG to PET: The Training of the School. Clopton Aud., 4950 Children's prof, of comparative lit, State U. of N.Y. at Wednesday, Oct. 15 Professor of Music. Olin Library, Lvl. 1, Radiologists of Tomorrow." Joseph K.T Place. 454-6006. Stonybrook, and Eric Cazdyn, assoc. prof, 8 a.m. Obstetrics & Gynecology Grand Special Collections. 935-5495. Lee, prof, and chair of radiology, U. of Rounds. "Hypotension, Fetal Bradycardia, N.C. Scarpellino Aud., 510 S. 9-10 a.m. Washington University of comparative lit. and East Asian and cine- and Hemorrhage in Association With Kingshighway Blvd. 362-2866. Language Learning Colloquium Series ma studies, U. of Toronto. U. of Mo.-St. Friday, Oct. 17 Louis Millennium Student Center, Lvl. 3. Spinal/Epidural Anesthesia." Tom A. Davis, 6 p.m. Architecture Monday Night Lecture Workshop. "A Language Learning 9:15 a.m. Pediatric Grand Rounds. 935-4448. assoc. prof, of anesthesiology and of Series. "Works." Conxita Balcells Blesa, Strategy: Production Before "Molecular Imaging of Gene Expression obstetrics & gynecology. Clopton Aud., architect and visiting assoc. prof, of archi- Comprehension." Merrill Swain, profes- and Protein Function in Vivo." David 4950 Children's Place. 362-1016. tecture. (5:30 p.m. reception, Givens sor, Ontario Inst. for Studies in Monday, Oct. 13 Piwnica-Worms, prof, of radiology and Education. U. of Toronto. Lab Sciences Noon. Neurology & Neurosurgery/CSNSI Hall.) Steinberg Hall Aud. 935-6200. Noon. Molecular Biology and Pharmacology of molecular biology & pharmacology. Bldg., Rm. 300. 935-5175. Seminar. "Brain-computer Inter-faces: & Neurology Seminar. "Liberation of Clopton Aud., 4950 Children's Place. Cortical Neuroprosthetics." Daniel Moran, Noon. Cell Biology & Physiology Seminar. Intracelluiar Zinc and Neuronal Cell Death." 454-6006. Tuesday, Oct. 21 asst. prof, of biomedical engineering. "Extracellular Proteolysis in Epithelial Elias Aizenman, prof, of neurobiology, U. of Maternity Bldg., Schwarz Aud. 362-9460. Noon. Cell Biology & Physiology Seminar. Noon-1 p.m. Program in Physical Therapy Repair and Defense." William C. Parks, Pittsburgh. South Bldg., Rm. 3907, Philip "Monogenic Cardiomyopathies Related to Research Seminar. Ann Marie, Dale, record.wustl.edu WASHINGTON UNIVERSITY IN ST. LOUIS Oct. 10,2003 5

Author Teachout to read Oct. 13-14 Critic Vendler, poet Graham in 'Conversations About Poetry' BY LIAM OTTEN lution in public schools — work- bers 1931-1959 (1989) and ing with defense attorney Cla- Beyond the Boom: New Voices BY LIAM OTTEN Terry Teachout, author of rence Darrow to put prosecutor on American Life, Culture, and The New York Times Not- William Jennings Bryan on the Politics (1990). His latest col- Renowned critic Helen Vendler able Book The Skeptic: A witness stand. lection, A Terry Teachout and Pulitzer Prize-winning Life ofH.L. Mencken, will read In writing The Skeptic, Teach- Reader, will be published by poet Jorie Graham will partici- for the 2003-04 Center for the out relied chiefly on Mencken's Yale University Press in the pate in a three-day discussion on Humanities' Writers Series private, autobiographical papers, spring. poets and poetry Oct. 15-17 as Oct. 13-14. which had been sealed upon the Teachout began his career part of the University's Fall Teachout will host two journalist's death. Teachout began as a music critic for The Kan- Reading Series 2003, sponsored events while at the University. working with the material in 1992 sas City Star and served as edi- by The Writing Program and the Vendler Graham He will read from his work at 8 during his tenure as arts colum- tor of Harper's Magazine be- Department of English, both in p.m. Oct. 13 in Anheuser- nist for The New York Daily News, fore joining The New York Arts & Sciences. Harvard University, is one of Busch Hall, Room 204. And at when he discovered and later edit- Daily News as editorial writer, "Conversations About Poetry" the nation's most influential 4 p.m. the next day, he will lead ed the manuscript for A Second classical music critic and dance will kick off at 8 p.m. Oct. 15 poetry critics. a seminar and audience discus- Mencken Chrestomathy (1995), a critic. He is a music critic for with Vendler speaking on Her books include Coming of sion on the craft of writing in collection of essays, reviews and Commentary, a drama critic "Intimacy in the Lyric: John Age As a Poet: Milton, Keats, McMillan Hall, Room 115. reportorial pieces selected and for The Wall Street Journal and Ashbery's 'Self-Portrait in a Eliot, Plath (2003); Seamus The Skeptic: A Life ofH.L. annotated by Mencken but never a contributor to The Washing- Convex Mirror.'" The talk, which Heaney (1998); The Art of Mencken (2002) is the first full- published. ton Post, for which he writes will examine the relationship Shakespeare's Sonnets (1997); length biography of the great "I am like Mencken," Teach- the column "Second City" between Ashbery and the reader The Breaking of Style: Hopkins, and controversial journalist out said, "a working journalist, about the arts in New York as well as between Ashbery and Heaney, Graham (1995); Wallace H.L. Mencken (1880-1956) to and have spent most of my adult City, where he resides. Renaissance painter Francesco Stevens: Words Chosen Out of appear in more than 30 years. life writing for and editing Teachout's reading and Parmigianino, will be held in Desire (1984); and Parr of Mencken was a powerful voice American magazines and news- seminar are both free and Hurst Lounge, located in Nature, Part of Us (1980), for in American politics and cul- papers. It stands to reason that open to the public and are Duncker Hall, Room 201. which she won the National ture during the first half of the the openings of Mencken's sealed sponsored by The Center for At 8 p.m. Oct. 16 in the Book Critics Circle Award in 20th century, writing for the memoirs of his professional life the Humanities in Arts 8c Women's Building, Vendler and criticism. Sun and Evening Sun newspa- would have played a part in my Sciences (formerly the Inter- Graham will host a dialogue "Helen Vendler is the finest pers in his native Baltimore, as decision to undertake a new national Writers Center in Arts about Graham's work, her influ- and deepest evaluator and read- well as for The New Yorker and biography of so celebrated an 8c Sciences). ences and the state of contempo- er of poetry I know," said his own The Smart Set and The author and editor." Copies of Teachout's works rary poetry. Naomi Lebowitz, Ph.D., the American Mercury magazines. Teachout previously authored will be available for purchase, The series will conclude with Hortense and Tobias Lewin In 1925, he played a key role City Limits: Memories of a Small and a book-signing and recep- a reading by Graham at 8 p.m. Distinguished Professor Emerita in the infamous Scopes trial in Town Boy (1991) and edited tion will follow each program. Oct. 17 in the Women's Building. in the Humanities in Arts & Dayton, Tenn. — the trial that Ghosts on the Roof: Selected For more information, call Vendler, the A. Kingsley Sciences. "And she has the gift, challenged the teaching of evo- Journalism ofWhittaker Cham- 935-5576. Porter University Professor at as well, of transmitting her thoughts, whether she is han- dling the best poets of the past Processive Motor Enzyme." Jeff Gelles, Aron and Imre Tauber Professor of or the present, so elegantly, inci- Biochemistry and Molecular Pharma- And more. ♦. sively, accessibly, that she stirs cology, Brandeis U. Cori Aud., 4950 us to a rich re-reading. Children's Place. 362-0261. Saturday, Oct. 11 "This is a judgment shared 4-6 p.m. Bench Dedication Ceremony and by the academic world at large, Thursday, Oct. 23 Reception. Traditional Japanese tea- here and abroad." 8 a.m.-5 p.m. St Louis STD/HIV house waiting bench, by Tamotsu Edo, Graham, the Boylston Prevention Training Center CIYIE master carpenter, Awajishima, Japan. Co- Professor of Rhetoric and Course. "Syphilis Update." (Continues sponsored by the Visiting East Asian 8:30 a.m.-5 p.m. Oct. 24.) Cost: $50. Professionals Program and the School of Oratory at Harvard, is the Bernard Becker Medical Library, Rm. Architecture. Elizabeth Danforth Butterfly author of numerous collections 601 A. To register, call 747-0294. Garden. 935-8772. of poetry, most recently Never Noon. Genetics Seminar Series. (2002), Swarm (2000) and The "Functional Genomic Analysis of Stem Monday, Oct. 13 Errancy (1997). Cells and Germ Cells in C. elegans." 11:30 a.m.-4:30 p.m. Blood Drive. Co- She received a Pulitzer Prize Valerie Reinke, asst. prof, of genetics, sponsored by Sigma Nu Fraternity, Alpha in 1996 for Dreams of the Uni- Yale U. McDonnell Medical Sciences Epsilon Phi Sorority, Congress of the Bldg., Rm. 823. 362-2139. fied Field: New and Selected South 40 and the Office of Human Poems 1974-1994. Other honors 4 p.m. Chemistry Seminar Series. Resources. (Also 11:30 a.m.-4:30 p.m. "Biophysical Approaches to Mettaloend- Oct. 14, Mallinckrodt Student Center, include a John D. and Catherine onuclease Structure and Function." Lower Lvl., The Gargoyle; and 5-10 p.m. T MacArthur Fellowship and Cynthia M. Dupureur, prof, of chemistry, Oct. 15 & 16, Wohl Center, Friedman the Morton Dauwen Zabel Total recall? U. of Mo.-St. Louis. McMillen Lab., Lounge.) Mallinckrodt Student Center, Award from the American Lower Lvl., The Gargoyle. 658-2004. The Communications & Rm. 311.935-6530. Academy and Institute of Arts Journalism Program in 5 p.m. East Asian Studies Lecture. 8 p.m. Center for the Humanities Writers and Letters. University College in Arts & Annual Nelson L. Wu Memorial Lecture Series Reading. Terry Teachout, author. Anheuser-Busch Hall, Rm. 204. "Jorie Graham is among our Sciences recently sponsored on Asian Art and Culture. "The Musical 935-5576. finest, most authentically origi- "The California Recall: A Archaeology of Ancient China: A Presentation of Art and Music." Lothar nal American poets, passionate- Forum With Experts." The von Falkenhausen, prof, of art history, U. Wednesday, Oct. 15 ly committed to the poem as a forum included local political of Calif., Los Angeles. Co-sponsored by quest at once intellectual, spiri- 8 p.m. Writing Program Reading Series. experts and focused on the the Saint Louis Art Museum. Saint Louis tual and erotic," said Carl procedures, laws, possible Art Museum Aud., 1 Fine Arts Drive. Helen Vendler, author, literary critic and A. Kingsley Porter Professor of English, Phillips, professor of English consequences, media and 935-4448. Harvard U. Duncker Hall, Rm. 201. Hurst and of African and Afro- political controversies sur- Lounge. 935-7130. rounding the California recall American Studies in Arts & Sciences. "Her project is noth- election. Above, Ava Erlich, Thursday, Oct. 16 executive producer of special Music ing less than to stake out a place projects at KSDK Channel 5, 8 p.m. Writing Program Reading Series. for meaning on the ground of Helen Vendler, author, literary critic and makes a point during the Thursday, Oct. 16 language as it shifts beneath us." A. Kingsley Porter Professor of English, All the events are free and forum as Jeff Smith, graduate 8-10 p.m. Jazz at Holmes. Paul DeMarinis Harvard U., and Jorie Graham, poet and student and instructor in polit- Quartet. Ridgley Hall, Holmes Lounge. Boylston Professor of Rhetoric & open to the public, and a book- ical science in Arts & 935-4841. Oratory, Harvard U. Women's Bldg. signing and reception will fol- Sciences, looks on. (At left, 935-7130. low each. Copies of Graham's top to bottom) Repps Hudson, and Vendler's books will be co-coordinator of the Friday, Oct. 17 available for purchase. Communications & Journal- On Stage 8 p.m. Writing Program Reading Series. For more information, call ism Program, business Jorie Graham, poet and Boylston Pro- 935-7130. reporter and former political Friday, Oct. 10 fessor of Rhetoric & Oratory, Harvard U. editor of the St. Louis Post- Women's Bldg. 935-7130. Dispatch, moderates the ses- 8 p.m. Performing Arts Department Performance. Guys and Dolls. Jeffery sion, which included panelists Matthews, dir. (Also 8 p.m. Oct. 11,17, N. Paul Dusseault, senior & 18; and 2 p.m. Oct. 12 & 19.) Cost: vice president and partner at $12, $8 for seniors and WUSTL faculty, Fleishman-Hiilard Inc., and Jo staff and students. Edison Theatre. Record (USPS 600-430: ISSN 1043-0520), Mannies, political reporter for 935-6543. Volume 28, Number 9/0ct. 10, 2003. Founded in 1905 the Post-Dispatch. Published for the faculty, staff and friends Washington University community news of Washington University. Produced weekly Editor Kevin M. Kiley during the school year, except school KEVtN LOWDEH PHOTOS Sports Associate Editor Andy Clendennen holidays, and monthly during June, July and Assistant Editor Neil Schoenherr August by the Office of Public Affairs, Associate Vice Chancellor Judith Jasper Leic'it Washington University, Campus Box 1070, research asst. in internal medicine. 4444 Wednesday, Oct. 22 Saturday, Oct. 18 Executive Editor Susan Killenberg McGinn One Brookings Drive, St. Louis, M0 63130. Forest Park Blvd., Rm. B108/B109. Medical News Editor Kimberly Leydig 8 a.m. Obstetrics & Gynecology Grand Noon. Football vs. U. of Chicago. Periodicals postage paid at St. Louis, M0. 286-1404. Production Carl Jacobs Rounds. "Improving Patient Safety and I Homecoming Game. Francis Field. Where to send address changes 4 p.m. Religious Studies Lecture. Wither- Reducing Medical Errors." Victoria 935-4705. News & Comments spoon Lecture in Religious Studies. Fraser, prof, of medicine. Clopton Aud., (314) 935-6603 Postmaster and nonemployees Record, "Cosmic History: Law, Chance and 4565 McKinleyAve. 362-1016. Campus Box 1070 Washington University, Campus Box 1070, Design." Ian Barbour, Winifred & Atherton Wednesday, Oct. 22 [email protected] One Brookings Drive, St. Louis, MO 63130. Bean Professor Emeritus of Science, Noon-1:30 pm. History & Philosophy of 7 p.m. Men's Soccer vs. Webster U. . Medical News Technology and Society, Carleton College. Science Seminar. "State Control of Francis Field. 935-4705. Employees Office of Human Resources, Lab Sciences Bldg., Rm. 300. 935-7762. Soviet Science: Documenting Through (314)286-0119 Washington University, Campus Box 1184, Data Mining." Vadim Birstein, chairman, 7 p.m. Volleyball vs. Southern III. U.- Campus Box 8508 One Brookings Drive, St. Louis, M0 63130. 5:30 p.m. Medical Humanities and Social Sturgeon Conservation International, New Edwardsville. Athletic Complex. [email protected] Sciences Meeting. "J. Marion Sims and York. Life Sciences Bldg., Rm. 202. 935-4705. the Vesico-vaginal Fistula: A Reconsi- 935-6808. deration." Lewis Wall, assoc. prof, of obstetrics and gynecology. Bernard 4 p.m. Biochemistry & Molecular I WishingtDnUniversity in StlDuis Becker Medical Library, King Center. Biophysics Seminar. "How Kinesin 935-5340. Keeps Its Grip: The Mechanism of a 6 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS Sports

Football quells rally, for 333 yards and two touch- Carnegie Mellon University Oct. 5 finishing the 6K course in won the 50 freestyle (21.58) and downs. McCarthy led the Bears on at Francis Field. Freshman Sara 23:26.54 to take 28th place. the 200 breaststroke (2:14.96). holds off Rhodes 28-21 the ground with 18 carries for 76 Schroeder scored both goals for WUSTL placed eighth. Ohio State Classmate Michael Slavik edged the Bears, who extended their won the team title. SLU's Christopher Johansen in The football team held off a late yards and a touchdown. unbeaten streak to 10 games. Top-seeded Rathi Mani and the 200 free, and followed that fourth-quarter rally and defeated WUSTL has not lost since a sea- Lauren Zwick dropped a three-set with a win in the 100 free. Rhodes College, 28-21, Oct. 4 at Other updates son-opening 5-0 setback at No. 2 heartbreaker to Erin Coughlin Sophomore Tracey Hendrick- Francis Field. The Bears had a 21- The No. 2-ranked volleyball Wheaton College. Schroeder got and Lauren Gerlach of Denison in son paced the Bears women, fin- 10 lead heading into the fourth team went 3-0, defeating Case the Bears on the board in the the final of the women's tennis ishing first in the 1,000 freestyle. quarter before Rhodes began the Western Reserve University, 3-0, ninth minute as she picked up a main doubles draw at the 2003 Hendrickson recorded a pool comeback. Midway through the the University of Rochester, 3-1 lose ball in the Carnegie Mellon Intercollegiate Tennis Association record time of 10:37.56. She also fourth quarter, Rhodes tied the and the University of Chicago, box and beat goalkeeper Megan Omni Central Region Champion- won the 500 free (5:14.92). game at 21. But after the tying 3-0, at the University Athletic Monroe with a shot to the right ships Oct. 5. After taking the first Paul Thornton has been field goal, Bears senior Blake Association Round Robin No. 1. corner. set 6-2, Mani and Zwick fell be- named the men's and women's Westra had a season-long 44-yard The Bears (15-3, 3-0 UAA) hit a The men's cross country. hind 2-5 in the second. However, track and field coach. Thornton return on the ensuing kickoff, season-best .477 against Roch- team placed fourth of 10 teams they won four of the next five replaces Steve Rubin, who took which set up the Bears five-play ester. Oct. 4 at the Indiana State games to force a tiebreaker before a similar position at Florida drive for the game-winning touch- The men's soccer team Invitational in Terre Haute, Ind. Denison prevailed 7-6 and evened International University. down. Junior Adam Meranda con- dropped its UAA opener Oct. 5, Sophomore Brennan Bonner the match at one set apiece. Thornton comes to Washington nected with sophomore Brad 1-0 against 13th-ranked and paced the Bears in the 8K run, The men's and women's University from Saint Mary's Duesing a 20-yard reception, and undefeated Carnegie Mellon completing the course in 26:02 swimming and diving team University in Winona, Minn., junior Kevin McCarthy ran for 19 University. After battling to a 0-0 and placing 17th. Classmate Greg opened the 2003-04 season Oct. 4 where he had been the Card- to the Rhodes 2-yard line. standstill for more than half the Reindl finished 22nd in 26:18, against Saint Louis University at inals head men's and women's Meranda scored on a 2-yard run game, CMU's Jonathan Browne and senior Darius Viet also Millstone Pool. Despite numerous coach for the past three seasons. on the next play to give WUSTL a netted the game-winning goal at cracked the top-30, posting a strong individual efforts, the During his tenure, Thornton 28-21 lead. Duesing finished the the 68:37 mark to secure the win. 26:35 mark to finish 27th. The Bears women fell 191-102 and the coached one All-American, one game with 11 catches for a season- Washington U and CMU had Bears registered 100 team points, men lost 172-119. On the men's Minnesota Intercollegiate high 189 yards as he moved into seven shots apiece, but the Tartans just two points shy of third place side, sophomore Eric Triebe won Athletic Conference (MIAC) seventh place all-time at the held a 7-3 corner kick advantage. and host Indiana State. On the the 100-yard breaststroke in record holder, 14 MIAC cham- University with 107 career recep- The women's soccer team women's side, freshman 59.40, five seconds ahead of the pions and was a part of 35 tions. Meranda finished 22 of 36 won its UAA opener 2-0 over Elizabeth Herndon led the Bears, second-place finisher. He also school records.

have 300 surrogate children!" The South 40 staff is happy to Family have the Metzidakises on board. - from Page 1 "I am pleased that Stamos and his family have joined our faculty fellows program," said "Students see me in shorts or Justin X. Carroll, director of resi- wearing tennis shoes. They see dential life. "His more than 20 me working in my office. I think years teaching at the University, it helps to show them that faculty his enthusiasm for undergradu- are studying and working and ate education and his past partic- doing many of the same things ipation in our freshmen floor students are doing." Faculty Associates Program make The Metzidakises have two him well suited for this impor- children in college, so they know tant position. a few things about how students "The Metzidakises also offer a react to the experience of living unique perspective as they are on their own for the first time. parents of two college students." Metzidakis has been working Metzidakis has planned sever- with students almost since the al new programs for residents day he arrived at the University this year. He has proposed a 22 years ago. "Classics of World Cinema" film He was one of the first faculty series that will showcase a film Stamos Metzidakis, Ph.D. (left), professor of French and of comparative literature, both in Arts & members involved in the Faculty from a different country each Sciences, and wife Sarah (center) chat with students (from left) Andrew Sapthavee, Jenny Tuan and Associates Program, which also month of the academic year. Wayne Chuang in the Metzidakis' apartment in the Park/Mudd Residential College. The Metzidakises provides opportunities for signifi- There will be Monday Night are the newest faculty family on the South 40. cant faculty-student interaction Football parties, a Super Bowl outside the classroom setting. party, cooking contests, St. Louis nected to the students," Metzi- especially for the students." ball fan and never misses a He's been an on-site director of a jazz bands and student talent dakis said. "It's a great balance. I When Metzidakis isn't teach- game, either in person or on tel- year abroad program and a sum- shows. think the University has come ing or researching, he's traveling. evision. mer institute in France. And Sarah loves to cook, so up with a great idea with this He and Sarah have been all over "We are both very excited "It was a very natural transi- residents will be treated to sever- program, and I suspect that the world. about being a faculty family," he tion when they proposed this to al home-cooked meals. once faculty families have The couple also enjoys jazz said. "I think it will be a great me," he said. "Our kids are out of "We do have a sense of inde- moved into all nine residential and blues music, watching opportunity to share our inter- the house now, so in a sense this pendence in our living arrange- colleges, it will be a wonderful movies and entertaining. ests and ideas with students and is a nice substitution — we now ment, but we are also very con- program for the University and Metzidakis is a rabid Rams foot- to learn from them as well."

undergraduate and graduate stu- engineers now use a catalyst with a the whole process to maximize the associate director of CREL; P.A. dents, and the CEBC will also strong sulfuric or hydrofluoric acid, environmental benefit. Ramachandran, Ph.D., professor Center have a K-12 outreach component. which are difficult to contain and "Ultimately, we want to show of chemical engineering; and Jay from Page 1 According to Dudukovic, also are hazardous. The clean alternative that chemistry can be done cleanly R. Turner, Ph.D., associate pro- the director of the University's is a new type of solvent that would and we can have good products fessor of chemical engineering. school. Chemical Reaction Engineering completely eliminate the use of the made cleanly in ways that won't Turner is also serving as the "Providing our longstanding Laboratory (CREL), the center current acids and make the same pollute." education co-director for the expertise in chemical and envi- will enhance the University's abil- product in a clean way. Kansas brings strengths in center. ronmental engineering to a great ity to attract quality students, bet- Scientists at the University of molecular catalysis, he said, while The NSF is an independent team of engineering comple- ter collaborate with industry Kansas have shown that carbon Iowa has strengths in biocatalysis. federal agency that supports ments the expertise of our part- partners, reach out to area K-12 dioxide could be used as an envi- Washington University brings its fundamental research and edu- ners at the universities of Iowa schools and expand collabora- ronmentally benign solvent. The expertise in transferring molecular cation across all fields of science and Kansas, and we are particu- tions within the University, while collaboration at CEBC will estab- phenomena to the engineering of and engineering. The focus of larly grateful for the leadership simultaneously developing better lish whether a viable process can be benign processes. the ERC program is to develop brought to bear on this successful reactors to accommodate novel developed based on this concept. "While at the moment, new technologies to benefit U.S. proposal by the University of catalysts promoting green chem- Among many research thrusts, Washington University activities industry by fostering collabora- Kansas. Now, the real work can istry. Dudukovic said the University and are focused on CREL, the center tion with academic and indus- begin, work which promises to The center will focus on sci- its collaborators will be looking at brings significant opportunities trial researchers across disci- improve the quality of life and ence and engineering needed to new ways to do liquid oxidation of in our Environmental Engi- plines. the human condition." establish environmentally benefi- hydrocarbons that are involved in neering Science Program by The CEBC expects to receive Byrnes noted that the center cial catalytic processes — it will the creation of precursor chemicals expanding the program's capabili- $17 million from the NSF dur- is the first NSF engineering re- seek ways to make myriad chemi- for everyday products such as ties from aerosols to sustainable ing the first five-year funding search center of any kind at cal intermediates in a way that nylon and polyester fibers. While technology development," Duduk- period. The three universities Washington University. does not damage the environ- the center's researchers will not be ovic said. "Additional interaction will collectively provide $2 mil- Catalysis is the acceleration of ment and is officially sustainable. making the final fiber, they will be with our Olin School of Business, lion toward this effort. a chemical reaction through the "Participation in this center exploring ways to more efficiently our Environmental Studies The center will employ about presence of a material — a cata- will allow us to combine all scales create the materials needed to Program and other Arts 8c 35 persons, including under- lyst — that is chemically un- of investigation, starting with the make these products. Sciences areas are encouraged." graduate and graduate students, changed by reaction. Catalysts are molecular and going to the large "The center will encourage Dudukovic said numerous postdoctoral scientists, adminis- the mainstay of chemical reac- scale, to invent new catalysts that industry to explore innovations companies have committed to trative and technical staff. tions, essential to the production function in an environment with us by allowing industrial part- participation in the center. They Nearly 15 major chemical of many products including which will allow us not to use ners to leverage the resources of our are: DuPont, Dow, Monsanto, companies are expected to join medicines, foods, plastics, fibers, nasty solvents and not to make three universities to develop green Exxon Mobil, Lyondell, Praxair, the CEBC as industrial partners, semiconductors and gasoline, nasty byproducts," Dudukovic chemistry," he said. "We will be Procter & Gamble, Rohm & Haas who will pay membership fees among others. said. "This will help us and our working with the three universities and UOP. At least six others have and will have the first opportu- Part of the activities of the collaborators truly abide by the in our specialties to advance the shown interest. nity to implement new tech- CEBC will be focused on under- principles of green chemistry and state-of-the art. We have test beds, The other University faculty nologies devised by the center. standing how catalysts work, green engineering to make these which over a period of a few years that participated in preparing the Ultimately, CEBC will sustain developing new catalysts and chemicals in a clean way." will be showing people how this center proposal and will be its growth and innovation with enabling them to function in For example, Dudukovic noted new science can create a catalyst, a involved in its work are: Muthana funding from industrial mem- environmentally friendlier sol- that in both the production of best reactor-separator* to accommo- Al-Dahhan, Ph.D., associate pro- berships and additional spon- vents. The research will involve detergents and high-octane fuels, date it, and do modern control on fessor of chemical engineering and sors of research projects. record.wustl.edu WASHINGTON UNIVERSITY IN ST. LOUIS Oct. 10,2003 7 Notables

Research Grant Program." ... Heinz M. Schaettler, Ph.D., Of note associate professor of systems sci- ence and mathematics in engi- Bijoy K. Ghosh, Ph.D., professor neering, has received a three-year, of electrical and systems engineer- $102,531 grant from the National ing, has received a three-year, Science Foundation for research $256,101 grant from the National titled "Analysis of Optimal Science Foundation for a study Control Problems with State titled "Feedback Control of Visual Space Constraints Arising in Appearance with Maximally Sens- Applications." ... itive Sensors for Decentralized Jan Amend, Ph.D., assistant Event Detection and Security." ... professor of earth and planetary Eliot M. Fried, Ph.D., associate science in Arts & Sciences, has professor of mechanical and aero- received a one-year, $30,000 space engineering, has received a grant from Arizona State Univer- three-year, $128,913 grant from sity for research titled "Theoret- the National Science Foundation ical Organic Geochemistry of for a study titled "Surface and Submarine Hydrothermal Sys- Actuation Kinetics of Stimulus- tems." ... Responsive Hydrogels." ... Ron K. Cytron, Ph.D., profes- Enterprising SCholarS (From right) University Trustee Andrew Taylor, chairman and chief Kenneth J. Goldman, Ph.D., sor of computer science in engi- executive officer of Enterprise Rent-A-Car Co., and Chancellor Mark S. Wrighton chat with associate professor of computer neering, has received a three-year, Enterprise Rent-A-Car Scholarship recipients Lana Beverly, Joshua Marshack and Lauren Grady science in engineering, has $494,779 grant from the National at the Enterprise Scholars Dinner Oct. 1 at the Charles F. Knight Executive Education Center. The received a three-year, $499,996 Science Foundation for research scholarship fund, which was established in 2001 with a $25 million gift by Enterprise Rent-A-Car grant from the National Science titled "ITR/NGS: High-Perform- Co., is the single largest scholarship gift for undergraduates in University history. Foundation for research titled "An ance Configurable Hardware Interactive Learning Environment Using Liquid Architecture." ... for Introductory Computer Dewey Holten, Ph.D., profes- for research titled "Mechanisms icine, has received the three-year, Ernesto Bernal-Mizrachi, Science." ... sor of chemistry in Arts & of Cell/Matrix Interactions with $225,000 Arthritis Investigator M.D., instructor in medicine, Jonathan B. Losos, Ph.D., Sciences, has received a three- the Kidney." ... Award from the Arthritis has received a one-year, associate professor of biology in year, $450,000 grant from the Jack R. Engsberg, Ph.D., Foundation.... $138,000 grant from the Arts & Sciences, has received a National Science Foundation for research associate professor of Monica Bessler, M.D., assis- American Diabetes Association two-year, $11,172 grant from the research titled "Primary Electron neurological surgery, has received tant professor of hematology, has for research titled "Role of National Science Foundation for Transfer Processes in Photosyn- a two-year, $425,086 grant from received a three-year, $180,000 Akt in the Regulation of dissertation research titled thetic Bacterial Reaction the National Institute of Neurol- grant from the Aplastic Anemia Pancreatic Beta Cell Mass "Testing Hypotheses of Morpho- Centers." ... ogical Diseases and Stroke for and MDS International Found- and Function." ... logical Differentiation in the Int- Rudolf Husan, Ph.D., profes- research titled "Ankle Strengthen- ation for research titled "Genes, Devra B. Becker, M.D., clin- roduced Lizard, Anolis Segrei." ... sor of mechanical engineering, ing to Improve Gait and Function Chromosomes, and Bone Mar- ical research fellow, has received Robert Pollak, Ph.D., the has received a one-year, $25,000 inCP."... row Failure." ... a one-year, $5,000 grant from Hernreich Distinguished Prof- grant from the EPA for research Paul J. Goodfellow, Ph.D., Michael J. Brenner, M.D., the Cleft Palate Foundation for essor of Economics in Arts & titled "Dynamic CATT Compo- professor of surgery, has received postdoctoral trainee, has received research titled "The Long-Term Sciences and the Olin School of nents: Trajectory Aggregation a one-year, $153,000 grant from a one-year, $4,969 grant from the Clinical Outcome of Surgically Business, has received a two-year, Tool."... the National Cancer Institute for Plastic Surgery Educational Corrected Unilateral Coronal $550,000 grant from the John D. Tava M. Olsen, Ph.D., associ- research titled "rDNA Methyl- Foundation for research titled Craniosynostosis on Cranio- and Cath-erine T. MacArthur ate professor of business, has ation and Prognosis in Endo- "Molecular Basis for Neurogen- facial Development and Foundation for research titled received a three-year, $111,300 metrial Cancers." ... erative Effects of FK-506." ... Neuropsychological Function." "MacArthur Research Network on grant from the National Science Jin-Moo Lee, M.D., assistant Family and Economy." ... Foundation for research titled professor of neurology, has Henry L. Roediger III, Ph.D., "Collaborative Research: Operat- received a two-year, $248,424 Doctoral education forum hosted by GWB the James S. McDonnell Disting- ional Strategies for Price and grant from the National Institute uished University Professor of Service Quality Competition." ... of Neurological Disorders and BY JESSICA MARTIN welfare doctoral programs at psychology in Arts & Science, has Jeffrey Miner, M.D., associate Stroke for research titled "The accredited universities. It was received a three-year, $438,098 professor of medicine, has Role of Zinc in Focal Ischemic As part of the University's founded nearly 25 years ago to grant from the U.S. Department received a four-year, $878,225 Brain Injury." ... Sesquicentennial celebration, provide a forum for sharing ideas of Education for research titled grant from the National Institute Stanford L. Peng, M.D., the George Warren Brown School and strategies and for strengthen- "Cognition and Student Learning of Digestive and Kidney Diseases Ph.D., assistant professor of med- of Social Work will host "Shaping ing members' efforts at enhancing the Future of Doctoral Education doctoral education. in Social Work: National Meeting Marvin Peterson, Ph.D., pro- of Doctoral Programs in Social fessor of higher education at the Work" Oct. 17-18. University of Michigan, will give Obituary "Through hosting this meet- the conference's keynote address, ing, we will be able to celebrate "The Corporatization of the over 50 years of doctoral educa- University: Implications for tion at GWB in addition to dis- Doctoral Education." Soviak, professor emeritus of history, 76 cussing national issues in social Additional topics that will be work Ph.D. education," said covered throughout the confer- BY ANDY CLENDENNEN Army in the Korean conflict from diary of his often subversive Nancy Morrow-Howell, Ph.D., ence include student attrition, 1952-54. social and political observations professor of social work and chair interdisciplinary structures, fund- Eugene Soviak, Ph.D., professor He taught at the University of and political struggles. The diary of the GWB doctoral program. ing for doctoral students, the job emeritus of history in Arts & Chicago from 1960-69 and earned caused a sensation when it was This is the annual meeting of market and preparing students Sciences, died Friday, Oct. 3, a doctorate in Japanese history originally published in Japan in the Group for Advancement of for academic responsibilities. 2003, in St. Louis. He was 76. from the University of Michigan. 1948, and is today regarded as a Doctoral Education, an organiza- The meeting is closed to the A specialist in modern Soviak had a hand in one of classic. tion whose members are directors public. For more information, call Japanese intellectual history, the most important and com- Soviak's version was the first of established social work/social 935-6605. Soviak was on the faculty of the pelling documents of wartime time the text appeared in Department of History from 1969 Japan when he edited and trans- English. until his retirement in 1993. lated into English Kiyosawa Soviak received a Fulbright Born in Michigan in 1927, Kiyoshi's Ankoku Nikki as A Diary Fellowship and a Fulbright-Hays Campus Watch Soviak earned bachelor's and of Darkness: The Wartime Diary faculty grant, and was elected to master's degrees in Far Eastern of Kiyosawa Kiyoshi, published Phi Kappa Phi (1958) and Phi history, both from Wayne State in 1999. Beta Kappa (I960). The following incidents were reported to University Police Oct. 1-7. Readers with informa- Between 1942-45, the journal- tion that could assist in investigating these incidents are urged to call 935-5555. This infor- University, in 1951 and 1953. He Memorial services will be mation is provided as a public service to promote safety awareness and is available on the also spent 16 months with the ist Kiyosawa (1890-1945) kept a held privately. University Police Web site at police.wustl.edu.

Oct. 3 4:22 p.m. — A bicycle was stolen from the bike rack outside the 4:54 p.m. — A student reported Athletic Complex. The bike had her purse was taken from her been secured with a cable lock. Employment backpack, which she left unattend- ed between 1:50-2:20 p.m. in a Oct. 7 Go online to hr.wustl.edu (Hilltop Campus) or medicine.wustl.edu/wumshr (Medical Campus) to obtain complete job descriptions. second-floor studio of Bixby Hall. 10:04 a.m. —The Arts 8c Loss includes debit cards, cash and Campus Box 8002, Senior Research Sciences computing staff report- Regional Dir. of Temporary Filing Administrative a student ID. Development Clerk 040059 Asst. 040073 St. Louis, MO 63110, Technician 040383 ed the theft of one of the public- Hilltop or call 362-7196. 030252 Career Director Accounting & Professional Rater I access computer units from the Campus Margins Office 040062 Payroll Asst. Purchasing Coord. 040384 Oct. 4 For the most current 040074 040261 basement hallway of Eads Hall. Coordinator 040007 Senior Accountant Medical Asst. II 1:01 p.m. — An unknown person listing of Hilltop Admissions 040064 Loan Analyst Medical Secretary 040385 The securing cable had been cut Campus position open- stole a laptop computer bag in Counselor 040025 040075 III 040322 with a bolt cutter. The monitor ings and the Hilltop Payroll/Accounts Asst. Grants/Budget Cupples II Hall. A search of the Campus application Earth & Planetary Payable Manager Accounting/Payroll/ and keyboard were left behind. Specialist 040365 Purch I 040386 area found the bag near Bryan process, go online to Sciences Library 040065 Medical Total loss is estimated at $700. hr. wustl.edu. For more Assistant 040029 Assoc. Director, Medical Secretary I Professional Rater I Hall. A credit card was missing. information, call Hazardous Materials Business Library Campus (Part-time) 040369 040390 935-5906 to reach the Tech II040033 040066 Research Patient Medical Secretary II Additionally, University Police Human Resources This is a partial list of 1:56 p.m. — An unknown person Employer Relations Security Officer positions in the Coord./Professional 040391 responded to four reports of larce- Employment Office at 040370 damaged the doorknob of the West Campus. Coordinator 040037 040067 School of Medicine. Administrative ny, three lost articles, two reports Employees: Contact Radiation Safety Deputized Police Medical Asst. II Coord. 040409 electrical room in January Hall. General Lab the medical school's 040372 of fraud, two auto accidents, and Specialist I 040045 Officer 040070 Public Safety Officer Maintenance was advised of the Assistant-Part Time Office of Human one report each of tampering, 020237 Database & Network Human Subjects Resources at Patient Billing 040412 damaged door and that the door Services Rep. II assault, burglary, liquor violation, Business Administrator Monitoring Program 362-7196. External Public Safety Officer would not secure. The damage 040046 Supervisor 040071 candidates: Submit 040373 040413 resisting arrest and property Development occurred between 5 p.m. Oct. 3 Specialist 030334 Temporary Data Lab Technician IV resume's to the Office Research damage. Entry Clerk 040058 040072 of Human Resources, Technician II (Part- and 8 a.m. Oct. 4. 4480 Clayton Ave., time) 040374 8 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS Oct. 10, 2003 Washington People

Carol S. North was camping in rural Missouri with her two Great Danes on Sept. 11, 2001. Shortly after the hijacked planes crashed into the World Trade Center and the Pentagon, reporters started calling. Soon she had been tracked down and brought back to town. To understand why the media immediately went looking for North on that terrible day, you have to understand how she makes a living. North, M.D., is a professor of psychiatry in the School of Medicine and an expert on disasters. "Disasters happen, and terrorism is growing," she says. "So we need to be ready for the kinds of prob- lems that survivors encounter. We had worked with survivors of the Oklahoma City bombing, and those results provided a kind of 'road map' for mental health professionals who worked with the survivors of 9-11." Although other researchers had previously worked with disaster survivors, Washington Uni- versity investigators were the pioneers in disaster research methods. They began somewhat serendipi- tously after the flooding and the discovery of dioxin in Times Beach, Mo., in 1982. Shortly before the flooding, several Times Beach residents had been interviewed for the landmark Epidemiologic Catchment Area (ECA) study that was designed to learn about the prevalence of mental health problems in the United States. Because the ECA researchers from the University had already interviewed residents, a team of re- searchers — led by psychiatry faculty member and disaster research pioneer Elizabeth Smith, Ph.D. — Carol S. North, M.D., professor of psychiatry, prepares interview material for the World Trade Center was able to study the impact of the Times Beach dis- survival study with Barry Hong, Ph.D., professor of psychology in psychiatry and associate professor aster on mental health by interviewing those same of medicine. she stresses. Early in her studies, North had considered becom- ing a small-town doctor or maybe an ophthalmologist. But then she worked as a research assistant doing psy- chiatric epidemiology and enjoyed it. She also felt her own experiences gave her a unique Against all odds perspective. "One could make the argument that it doesn't take Psychiatrist and disaster expert Carol North inspires patients, colleagues somebody with a brain tumor to make a good brain surgeon," she says. "But in some regards, I have a bit of people a second time. Unfortunately for all of us, it seems certain that her an edge because I experienced the degree of human North teamed with Smith in 1987, and in the work will take on increasing importance in the suffering that psychiatric illness can bring." years since, she has traveled to more than a dozen post-9-11 era." North has devoted her career to the suffering — different disaster sites, interviewed more than 2,000 not only those who have survived disasters but also to survivors and analyzed reams of data. A miraculous recovery the homeless. For a decade, she was the psychiatrist for Her first trip was to Indiana to interview the sur- North says it's a miracle that she's even working Grace Hill Neighborhood Services, where she worked vivors of a plane crash. A military jet hit a Ramada today. with indigent and homeless people. Inn, and although the pilot ejected safely, 10 people Late in high school, she became very ill. During She even had to dodge bullets on the job. She was on the ground were killed. her freshman year of college, she was hospitalized at a Grace Hill clinic discussing patient cases with a BY JIM DRYDEN Later there was a mass murder in Arkansas and a and diagnosed with schizophrenia. Medications social worker when a gunfight began outside. They ~ cafeteria shooting in Texas. There were earthquakes helped with some of the symptoms, but the side slid out of their chairs and continued working on the and firestorms in California and the disastrous effects were severe. floor. Midwestern flood of 1993. In spite of the illness, she finished college and She also made "house calls," visiting homeless Through it all, she has learned a great deal about even started medical school at the University of patients in shelters, and occasionally provided services how disasters can affect psychiatric health. Iowa. But her illness worsened her first year and slightly outside of her normal routine. Some survivors get depressed. But the most com- ended up in the hospital again. The University of "I delivered a baby at one of those clinics," she says. mon psychiatric effect of a disaster is posttraumatic Iowa didn't think it was a good idea for North to "The primary-care doctor was at lunch, and I was the stress disorder (PTSD). Soldiers can develop PTSD continue her medical training. only doctor there when a young woman decided it was from battlefield experiences; disasters can cause the She had been hearing voices. Sometimes the time to have her baby boy." same problems for civilians. voices told her to kill herself, and she came close to A lifelong love Most of North's recent studies involve attacks on taking her own life. Desperate for some sort of When she's not traveling around the world to talk with civilians. She studied survivors of the 1995 Okla- help, North and her family turned to an experi- disaster survivors or working with the homeless in St. homa City bombing and found that 45 percent had mental therapy in which her blood was filtered in a Louis, North likes to run. A movement disorder has psychiatric problems in the six months following, process that might be compared to kidney dialysis. with 34 percent suffering from PTSD. She details the experience in her inspiring book, limited her mileage in recent years, but she's complet- ed two marathons and finished first in an ultrama- Much of North's current research focuses on the Welcome Silence. effects of terrorism. She's mulling over data she col- "They never demonstrated that the treatment rathon — a distance of about 37 miles. lected from survivors of terrorist bombings in was generally effective," North says. "There were North and her husband, Richard Olson, met when both were in seventh grade in the town of Clinton, Nairobi, Kenya. problems with the research, which eventually was Iowa. They later went to the prom together. North also worked with congressional staffers abandoned." who were exposed to anthrax. She has also recently She received the treatment for 20 weeks. During These days, they live with their Great Danes near Tower Grove Park. They own two old houses next received a grant to study Sept. 11 survivors who the second week, the voices suddenly stopped. door to each other and are slowly restoring them. worked at the World Trade Center. That was more than 20 years ago. North hasn't "Carol is one of the true stars in psychiatric required any medication or had any symptoms of Judging by one of their anniversary celebrations, epidemiology," says Charles F. Zorumski, M.D., schizophrenia since. it's quite a romance. North's husband always had the Samuel B. Guze Professor and head of the "I see myself as blessed with a sort of personal wanted a yellow Corvette, and after they had eaten Department of Psychiatry. "Over the past 10 to 15 miracle," she says. "It was just against all odds their anniversary dinner, the valet pulled up in years, she has become a national leader in under- because we know from experience in the field that her husband's present — the yellow Corvette she standing the psychiatric effects of disasters. few people recover or do as well as I've done. bought him. "It's just an experience that is so atypical that I She says in addition to a romantic heart, there would classify it as fairly miraculous." might be something about her past experiences and about working with disaster survivors that makes her A unique perspective want to savor life. North's next miracle came from the late Samuel "Disasters are sort of equal opportunity employ- Guze, M.D. ers," she says. "They select cross sections of the popu- When she applied to Washington University's lation. People from all walks of life typically are medical school, the dean's office asked Guze, the exposed to a single disaster event, and it's very com- former head of psychiatry and vice chancellor for pelling to see how such diverse people will respond. medical affairs, for his opinion. Years later, he "Interestingly, it's not all negative. Many people talked about his decision with Barry Hong, Ph.D., actually tell us about positive effects that have professor of psychology in psychiatry and associate occurred in their lives after these events." professor of medicine. That doesn't surprise Carol North. But then again, "Sam Guze had always been a champion of peo- she's experienced her share of miracles. ple who had mental health problems," Hong says. "He said Carol's case was one where as a depart- ment and a university, we had to practice what we "Carol is one of the true stars in preached. psychiatric epidemiology. Over the past "He really championed her cause. He had confi- dence she would succeed." 10 to 15 years, she has become a national North says it's a tribute to the School of leader in understanding the psychiatric Medicine that she was allowed to continue her studies. effects of disasters." "It's important that when patients get better CHARLES F. ZORUMSKI Carol North with her Great Danes in Tower Grove Park. they have the opportunity to pursue their dreams,"