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12ST0153_Answers_Brochure_Vitamins_v6.indd 1 4/6/12 2:34 PM

Project Title 12ST0153_Answers_Brochure_Vitamins_v6 On Strategy Copy Editor Type of Piece Brochure On Brand Creative Mgr. Bleed .25 Creative Mgr. R. Rinka Has Impact Sr. Creative Mgr. Trim 5 x 7 Designer T. Jones Has Clarity Creative Director Colors 4/4 Copywriter Status Final Output date 4/6/12 Revision # 6 beauty beauty Beauty

Answers about vitamins and What nutrients should I consider for bones & joints Bones & Joints supplements begin here. promoting the health of my hair, skin The best way to get the daily requirement of essential vitamins and nails? is to eat a balanced diet that contains a variety of foods from We often appreciate and distinguish beauty based on an outer cognitive Cognitive the food guide pyramid. In addition to eating well, vitamins appearance, but much more can be said about beauty when and supplements may help ensure your body gets all the keeping our inner health in mind. Vitamins, minerals and other nutrients it needs. Since these needs can vary depending on key nutrients play a very important role in maintaining healthy age, gender and other factors, such as pregnancy, we created hair, skin and nails — the outward representation of our digestive Digestive this helpful guide to vitamins and supplements. “beauty” within. Read on to learn how the Contents following nutrients can help

heart nourish and maintain the Heart Beauty ...... Page 3 health of your hair, Bones & joints ...... Page 8 skin and nails. Congnitive health ...... Page 18 • Alpha lipoic acid

immune • Biotin Immune Digestive health ...... Page 27 • Green tea extract Heart health ...... Page 31 • Lycopene Immune health ...... Page 38 • Vitamin C • Vitamin D prenatal

Prenatal Prenatal health ...... Page 43 • Vitamin E Children’s health ...... Page 50 Menopause ...... Page 56 children’s children’s Children’s

menopause 2

Menopause 3

12ST0153_Answers_Brochure_Vitamins_v6.indd 2-3 4/6/12 2:34 PM beauty beauty Alpha lipoic acid Vitamin C Alpha lipoic acid (ALA) is another important antioxidant in the Vitamin C is a key nutrient when it comes to skin health. body. Not only does ALA fight against damaging free radicals, Not only does it offer potent antioxidant activity in helping but it also helps to regenerate or recycle other key antioxidant to protect the skin, it is also necessary for the formation of nutrients, specifically vitamins C and E. The ability of ALA to collagen — an important compound naturally found in the skin regenerate other protective nutrients helps to enhance the that helps maintain the elasticity and integrity of the skin.4,5,6 antioxidant activity in the body and thus maintain healthy skin.3 Vitamin D Biotin Protecting the skin through the use of sunscreen is essential Biotin — a member of the B vitamins — is involved in the when it comes to reducing the risk of cellular damage from UV light. Unfortunately, the use of sunscreen with an SPF of maintenance of healthy hair, skin and nails. Individuals who are 15 or higher inhibits the skin’s ability to synthesize vitamin deficient in biotin may experience scaly skin, loss of hair and D — a critical nutrient involved in bone health and immune brittle nails. Individuals who are not meeting their daily need function, among other benefits. Thus, when protecting the skin for biotin can choose a daily biotin supplement to promote the by applying sunscreen, it is equally important to keep in mind 9 strength and health of their hair, skin and nails. alternative ways for ensuring adequate blood levels of vitamin Green tea extract D. Foods like salmon and fortified milk provide a moderate amount of vitamin D and can be a good way to meet your Green tea is an excellent source of antioxidants. Research suggests that the antioxidant compounds found in green tea may play a beneficial role in maintaining healthy skin, even in the presence of UV light from the sun.1,2 Consequently, green tea extract packed with antioxidants may be a helpful addition to your health regimen. Lycopene Lycopene is a carotenoid that plays a role throughout the body, including the liver, adrenal glands, lungs, prostate and skin. The intake of lycopene — through dietary sources like tomatoes and supplements — can be a great way to promote healthy skin.

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12ST0153_Answers_Brochure_Vitamins_v6.indd 4-5 4/6/12 2:34 PM beauty New in-stores Now! requirement if you consume multiple servings of each per day. For the many people who don’t get enough vitamin D through the diet, taking a daily vitamin D supplement can be a great way to fulfill your need for this very important nutrient.8 Foods like salmon and fortified milk provide a moderate amount of vitamin D and can be a good way to meet your requirement if you consume multiple servings of each per day. For the many people who don’t get enough vitamin D through their diet, taking a daily vitamin D supplement can be a great way to fulfill your need for Advanced this very important nutrient.8 Nutra-Cosmetics Vitamin E Vitamin E is a crucial antioxidant nutrient found in every cell of Superior Strength the body and helps to protect and maintain the integrity of all cells, including skin cells. As a result, ensuring adequate and Protection! vitamin E through the diet is vital for promoting cellular health and healthy skin.5,6,7

Nutrient Suggested use Alpha lipoic acid 50-400 mg per day

Biotin Up to 2,500 mg per day more products from: Green tea extract 50-400 mg standardized extract per day

Lycopene 10 mg per day Vitamin C 250-500 mg per day

Vitamin D 1,000-2,000 IU per day for adults • Higher amounts may be taken under a doctor’s supervision, especially if deficiency is present

Vitamin E 200-400 IU per day

REMEMBER: Please consult with your doctor before beginning any dietary supplement program or for specific concerns regarding your health condition or prescription medication.

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12ST0153_Answers_Brochure_Vitamins_v6.indd 6-7 4/6/12 2:34 PM bones & joints

Calcium bones & joints Calcium is essential for maintaining bone density and, in fact, How do I maintain healthy bones and joints? the vast majority of the body’s calcium — greater than 90 percent — is stored in bone. The daily recommended intake As we age, “wear and tear” on our joints from constant repetitive level for calcium is 1,000 mg per day. Calcium carbonate motion can contribute to joint problems and limit mobility. and calcium citrate are the two main forms found in dietary Following an ideal diet can be a challenge at times, so consider supplements. People who suffer from gastrointestinal starting a supplement program if you believe that it would be conditions (i.e, acid reflux) may find calcium citrate to be easier to your advantage. Dietary supplements can be a great way on the stomach and better tolerated than calcium carbonate. to support your nutritional needs by filling the nutrient gaps Talk to your doctor about what formula is right for you. that may exist. Remember, it is important to speak with your Chondroitin preferred healthcare provider or registered dietitian about a Chondroitin is a close “partner” of glucosamine when it comes supplement regimen for promoting bone and joint health. to improving joint health. It is a naturally occurring nutrient found Read on to learn how the following nutrients can promote in the connective tissue of the body that helps maintain the healthy bones and strong joints: structure and function of joint cartilage. Chondroitin lubricates and cushions the joints by creating a shock-absorbing space • Calcium within the cartilage tissues. Not only does this action provide • Chondroitin cushioning support, but it also helps protect cartilage from being • Glucosamine broken down by enzymes. If you suffer from moderate-to-severe • Hyaluronic acid joint pain, a combined chondroitin and glucosamine supplement • Magnesium may promote the health of your joints. Consult your doctor to see • Multivitamins if a combined chondroitin and glucosamine supplement may be • Omega-3 fatty acids right for you. • SAM-e Glucosamine If you are conscientious about the health of your joints, it is likely that you have already heard about glucosamine. Glucosamine is a basic building block for maintaining joint cartilage and the structural integrity of your joints. It also helps

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12ST0153_Answers_Brochure_Vitamins_v6.indd 8-9 4/6/12 2:34 PM bones & joints promote overall elasticity, flexibility and mobility of the joints. others, a multivitamin may lack a needed nutrient or may not Preliminary studies have found glucosamine to be superior to provide enough of a nutrient. In such cases, extra supplements placebos in promoting joint comfort and improved functionality may be necessary. bones & joints amongst populations. If you suffer from moderate-to-severe joint pain, consult with your doctor about whether dietary Omega-3 fatty acids supplementation with glucosamine may be right for you. The most important omega-3 fatty acids for your joints are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Hyaluronic acid EPA and DHA have positive effects on health, including joint Emerging research suggests that hyaluronic acid provides health. To get your dose of EPA and DHA, aim for at least lubrication and cushioning for the joints. It is a natural two weekly servings of fatty fish like salmon, halibut, tuna and component of cartilage and the synovial fluid of the joints, sardines. If you don’t eat much fish, taking a fish oil supplement and helps reduce friction between cartilage and other joint can be of help. tissue during movement.10 SAM-e Magnesium SAM-e (short for S-adenosylmethionine) is a naturally occurring The mineral magnesium may not come to mind with regard molecule in the body that is commonly associated with brain to bone health, but nearly 50 percent of the body’s supply of health and mood. While mood support is definitely a benefit, magnesium is found in bone. Of the 300 essential metabolic SAM-e can also play a role in joint health. SAM-e stimulates the reactions in the body that depend on magnesium, the synthesis of proteoglycans, which are necessary for the growth metabolism of bone is one of them. Magnesium is directly and repair of cartilage. Healthy cartilage not only protects your involved in the formation of bone and the maintenance of bone joints, but is also needed to maintain joint comfort. SAM-e is a density, which can help in the prevention of fractures. If you very delicate compound that reacts quickly in the presence of think you might be at risk of low magnesium levels, talk to your air and moisture. Look for a SAM-e product that is packaged doctor about taking a magnesium supplement.1,2,3 in blister packs, which help promote product effectiveness by limiting environmental exposure. Also, make sure your SAM-e Multivitamins supplement is enteric-coated. An enteric-coated formula means A daily multivitamin contributes to your nutritional status by that the product can travel through the stomach to the small filling the vitamin and mineral gaps that may exist in your diet. intestine where it is best absorbed. A daily multivitamin may be sufficient for some people, but for

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12ST0153_Answers_Brochure_Vitamins_v6.indd 10-11 4/6/12 2:34 PM bones & joints Nutrient Suggested use Calcium and vitamin D Calcium: 1,000 mg per day for adults in at least two divided doses ™ Vitamin D: 1,000-2,000 IU per day for adults More of What Matters to You • Higher amounts may be taken under a doctor’s supervision, especially if deficiency is present Chondroitin 800 mg per day Glucosamine 1,500 mg per day Hyaluronic acid 10 mg per day Magnesium 250 mg per day Omega-3 fatty acids 500 mg of EPA/DHA per day • Higher amounts may be taken under a doctor’s supervision SAM-e 400-1,200 mg per day • Dose varies for each individual. Talk to your doctor or preferred healthcare provider to determine your individual SAM-e dose.

REMEMBER: Please consult with your doctor before beginning any dietary supplement program or for specific concerns regarding your health condition or prescription medication.

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12ST0153_Answers_Brochure_Vitamins_v6.indd 16-17 4/6/12 2:34 PM cognitive

Acetyl-L-carnitine Acetyl-L-carnitine (known as ALCAR) is a compound that is How do I promote the health of my brain important in the process of energy metabolism. Carnitine’s main as I age? role is transporting fatty acids in the cell, which is an important step in energy production.4 Most people receive sufficient cognitive We hear about heart health, joint health and bone health, amounts of carnitine to meet daily needs. If you think you may be to name a few, but we do not often hear about brain health. at risk of low carnitine levels, talk to your doctor about taking a As the control center of your body, the brain is a vital organ that carnitine supplement. manages thousands of processes and communication lines that keep your body functioning at its best. B vitamins As the population grows older, most people can expect to B vitamins — particularly folic acid and vitamin B12 — help experience some degree of normal age-related cognitive maintain healthy homocysteine levels in the body. This is decline. Cognitive decline due to aging can affect multiple important because high homocysteine levels have been aspects of cognition, including the ability to process information, associated with reduced scores on tests designed to measure concentrate, memorize and reason. The supplements listed cognitive function.3 While scientists are still studying the have various roles in brain development and function throughout relationship between B vitamins and dementia, B vitamins various life stages from birth to adulthood. are effective in helping to manage homocysteine levels. The nutrients discussed in this section include Choline • Acetyl-L-carnitine Although your body can manufacture choline, it is also necessary • B vitamins: folic acid and vitamin B12 to obtain choline through your diet in order to get the amount • Choline your body needs to function optimally. • Multivitamins • N-acetyl-L-cysteine • Omega-3 fatty acids • SAM-e • Vitamin D

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12ST0153_Answers_Brochure_Vitamins_v6.indd 18-19 4/6/12 2:34 PM Choline is necessary for the production of acetylcholine, fatty acid found in the brain and is important for brain an important neurotransmitter involved in muscle control, development and function. memory and many other functions. It is also a component of Fatty fish like salmon, anchovies, sardines and halibut are cell membranes (the outer layer of the cell) and helps facilitate some of the most potent sources of DHA. Most people do not effective communication between cells. Food sources rich in eat enough servings of these fish in their usual diet, which is cognitive choline include egg yolk, beef, brussels sprouts and broccoli. why a fish oil supplement can be beneficial. For vegetarian consumption, flaxseed oil provides an omega-3 fatty acid

cognitive Multivitamins known as alpha-linolenic acid (ALA), which partly converts If you currently take a daily multivitamin, you may be wondering, to DHA in the body. ALA is also found in walnuts, almonds, “Do I need additional supplements?” A daily multivitamin avocados and other plant-based foods and oils. contributes to your nutritional status by filling the vitamin and mineral gaps that may exist in your diet. A daily multivitamin may SAM-e be sufficient for some people, but for others a multivitamin may SAM-e (short for S-adenosylmethionine) is a naturally occurring lack a needed nutrient or may not provide enough of a nutrient. molecule found in every living cell of the body, and is commonly In such cases, extra supplements may be necessary. associated with healthy brain function and mood. Discovered N-acetyl-L-cysteine over 30 years ago, SAM-e is best known for enhancing mood by promoting a healthy balance of brain neurotransmitters. N-acetyl-L-cysteine (known as NAC) provides the body with Levels of SAM-e tend to decline with age, so taking a an important amino acid known as cysteine. The body needs supplement that provides SAM-e can be cysteine to produce glutathione, a powerful antioxidant beneficial for overall brain health and compound that helps minimize the effects of free radicals. for individuals with mood Without enough cysteine, the body’s ability to synthesize health concerns. glutathione is weakened leading to potentially uncontrolled free-radical damage. This damage can affect various parts of the body, including the brain. Omega-3 fatty acids The most important omega-3 fatty acid for brain health is docosahexaenoic acid (DHA). DHA is the major polyunsaturated

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OCUVITE.COM Vitamin D Vitamin D is very important for healthy brain function and development. In addition, emerging research suggests that low vitamin D levels may be correlated with low performance on cognitive tests.

Nutrient Suggested use cognitive Acetyl-L-carnitine Supplement doses usually range from 500 -2,000 mg per day Antioxidant vitamins: Vitamin C: 250-1,000 mg per day AS WE AGE, OUR EYES CAN C and E Vitamin E: 200-400 IU per day B vitamins: 200-400 mcg per day folic acid and LOSE VITAL vitamin B12 25-1,000 mcg per day Choline Supplement doses usually range from 425-3,000 mg per day NUTRIENTS. Supplement doses usually range from 600-900 mg per day N-acetyl-L-cysteine ® Omega-3 fatty acids 500 mg of EPA/DHA per day for healthy individuals Give them Ocuvite . Uniquely formulated EPA and DHA to help replenish vital eye nutrients.* 1,000 mg of EPA/DHA per day for individuals with documented heart conditions SAM-e 200-1,600 mg per day • Recommended starting dose at 200 mg per day Vitamin D 1,000-2,000 IU per day for adults • Higher amounts may be taken under a doctor’s supervision, especially if deficiency is present

REMEMBER: Please consult with your doctor before beginning any dietary supplement program or for specific concerns regarding your health condition or prescription medication.

HELP PROTECT YOUR EYE HEALTH.*

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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Not redeemable for more than purchase price. Void where prohibited by 6 any person, firm, or group prior to store law and where reimbursed under Medicare, redemption. LIMIT ONE COUPON PER , or other government programs, PURCHASE. RETAILER: Factor Nutrition Labs and in states, including , that will reimburse you the face value of this prohibit patient rebates if a third party pays coupon plus 8 cents handling in accordance

any of the prescription price. Mail to: Bausch 00074 with our redemption policy (copy available & Lomb, CMS Dept. 10119, 1 Fawcett Dr., upon request). Consumer must pay any Del Rio, TX 78840. © 2012 Bausch & Lomb sales tax. Send all redeemed coupons to: Incorporated. Ocuvite is a registered trademark Factor Nutrition, Mandlik & Rhodes, PO Box of Bausch & Lomb Incorporated. All other 490 Dept #1055, Tecate, CA 91980 Cash product/brand names are trademarks of 26000 value: 1/100¢. Expires 5/1/13. their respective owners. Expires 5/1/13. 5 There’s never been a better time to do Offer good only Offer good only at Walgreens at Walgreens DigiCode® Data File ACCOUNT : 87272 MANDLIK RHODES INFORMATION SYSTEMS, INC. ORDERED BY : ERIC ABRAMSON P.O. NUMBER : FNL75461 INVOICE NO. : 1367154 ( EPS via EMAIL ) Encode: 81101072600007546135001100003130501 SYMBOL HEIGHT 0.8576 NBAR 0.0104 BWA ­0.0010 $5 off 1 focus factor adult 60 or 90 tab NOTICE: This DigiCode® file is considered original artwork. It must be inspected and approved by the purchaser. Use of this file confirms acceptance. Any modification of this file through scaling or distortion is prohibited. See back of the Symbology invoice for Limitation of Warranty. something about macular health. ICaps® Lutein and Omega­3 Vitamin Help: Once­ • PROTECT the retina with lutein* Daily $ $ • PROMOTE macular health* off • SUPPORT the natural defense system of the eye* off 5 ® 1 ® ICaps L&O Vitamins have ingredients studied in AREDS2. It’s the only once Prevagen Natrol® daily softgel with 10 mg of Lutein, 2 mg of Zeaxanthin and beneficial levels of Advanced Sleep for Clear Thinking Omega-3s to help support macular health.* Melatonin 10 mg. and Improved Memory Coupon good only in USA for product/ Recommend ICaps® Lutein & Omega-3 Vitamin to RETAILER: We will reimburse you the face quantity indicated. LIMIT ONE COUPON PER value of this coupon plus 8¢ handling HOUSEHOLD. Any other use constitutes your patients before another minute goes by. provided you and the consumer have fraud. Void if copied, transferred, sold, Visit icapsvitamins.com to learn more. complied with the terms of this offer. or where prohibited, restricted, or taxed. Invoices proving purchases of sufficient Consumer pays sales tax. Retailer: Quincy stock to cover presented coupons must be Bioscience will reimburse an authorized shown on request. Any other application retailer of our product the face value of may constitute fraud. Coupon void where this coupon, plus 8¢ handling, if submitted prohibited, taxed or restricted. Consumer in compliance with our redemption policy, *These*These statements have not been evaluated by the Food and Drug Administr statements have not been evaluated by the Food and Drug Administration.ation. must pay any sales tax. Cash value .001¢. available upon request. Mail to Quincy This product is not intended to diagnose, treat, cure, or pre This product is not intended to diagnose, treat, cure, or prevent vent any disease. any disease. Reproduction of this coupon is expressly Bioscience, 301 South Westfield Road, prohibited. Mail to: Natrol, Inmar Dept. Suite 200 Madison, WI 53717. Cash value © 2012 © 2012 Novartis 1/12 1/12 ICP12100JAD # 47469, One Fawcett Drive, Del Rio, TX of .001¢. 2012 Quincy Bioscience, LLC. 78840. Expires 5/1/13. Expires 5/1/13.

12ST0153_Answers_Brochure_Vitamins_v6.indd 24-25 78338 ICP12100JAD WG.indd 1 3/15/124/6/12 9:322:34 AMPM Offer good only Offer good only at Walgreens at Walgreens digestive

$ $ What nutrients can I take to promote strong 5off 5off digestive health? I-Caps® Lutein & I-Caps® AREDS® Omega-3, 30 ct. Softgels 120 ct. Softgels and Tablets Healthy digestion is key when it comes to keeping your body well. Coupon void if altered, copied, sold, Coupon void if altered, copied, sold, purchased, transferred, exchanged or where purchased, transferred, exchanged or where When you eat, the process of digestion facilitates the absorption prohibited or restricted by law. CONSUMER: prohibited or restricted by law. CONSUMER: Limit one coupon per specified item(s) Limit one coupon per specified item(s) and transportation of the important nutrients in food and makes purchased. This coupon good only on product purchased. This coupon good only on product those nutrients available for the body to use for essential functions sizes and varieties indicated. RETAILER: sizes and varieties indicated. RETAILER: ALCON LABORATORIES, INC. will reimburse ALCON LABORATORIES, INC. will reimburse like energy production and bone development. In addition, proper you face value plus 8¢, if submitted in you face value plus 8¢, if submitted in compliance with ALCON LABORATORIES, INC. compliance with ALCON LABORATORIES, INC. digestive health is involved in preventing toxins and harmful waste Coupon Redemption Policy dated 12/15/11, Coupon Redemption Policy dated 12/15/11, available upon request. Consumer must pay available upon request. Consumer must pay products from building up in the body. Thus, it is critical that you sales tax. Good only in USA. Send coupons sales tax. Good only in USA. Send coupons to ALCON CONSUMER DIVISION, CMS to ALCON CONSUMER DIVISION, CMS do your best to maintain a well-functioning digestive system by DEPARTMENT #00067, #1 FAWCETT DRIVE, DEPARTMENT #00067, #1 FAWCETT DRIVE, DEL RIO, TEXAS 78840. Cash value 1/20 DEL RIO, TEXAS 78840. Cash value 1/20 eating well, staying hydrated and engaging in regular physical cent. Expires 5/1/13. cent. Expires 5/1/13. activity. In addition, certain nutritional supplements can also help

Offer good only Offer good only promote good intestinal health and digestion. at Walgreens at Walgreens Read on to learn how the following nutrients may help to support the health of your digestive system and your overall health: • Multivitamin • Prebiotics $ $ • Probiotics 5off 5off • Vitamin D I-Caps® Multivitamin I-Caps® Lutein or 100 ct. Tablets Zeaxanthin 120 ct. Tablets Coupon void if altered, copied, sold, Coupon void if altered, copied, sold, purchased, transferred, exchanged or where purchased, transferred, exchanged or where prohibited or restricted by law. CONSUMER: prohibited or restricted by law. CONSUMER: Limit one coupon per specified item(s) Limit one coupon per specified item(s) purchased. This coupon good only on product purchased. This coupon good only on product sizes and varieties indicated. RETAILER: sizes and varieties indicated. RETAILER: ALCON LABORATORIES, INC. will reimburse ALCON LABORATORIES, INC. will reimburse you face value plus 8¢, if submitted in you face value plus 8¢, if submitted in compliance with ALCON LABORATORIES, INC. compliance with ALCON LABORATORIES, INC. Coupon Redemption Policy dated 12/15/11, Coupon Redemption Policy dated 12/15/11, available upon request. Consumer must pay available upon request. Consumer must pay sales tax. Good only in USA. Send coupons sales tax. Good only in USA. Send coupons to ALCON CONSUMER DIVISION, CMS to ALCON CONSUMER DIVISION, CMS DEPARTMENT #00067, #1 FAWCETT DRIVE, DEPARTMENT #00067, #1 FAWCETT DRIVE, DEL RIO, TEXAS 78840. Cash value 1/20 DEL RIO, TEXAS 78840. Cash value 1/20 cent. Expires 5/1/13. cent. Expires 5/1/13. 27

12ST0153_Answers_Brochure_Vitamins_v6.indd 27 4/6/12 2:34 PM Multivitamins Individuals with existing digestive concerns such as and absorption in the digestive tract and promote the growth inflammatory bowel conditions, lactose intolerance and of friendly bacteria. Individuals who may limit their intake of gluten sensitivity may be at risk of having low levels of certain soluble fibers can choose a supplement that contains prebiotic nutrients. They may have issues with absorption, which can ingredients.1,2 compromise their nutritional status, or they may limit their intake of certain foods, consequently limiting their intake of Probiotics key nutrients. For example, people who cannot tolerate dairy Probiotics are live microorganisms — primarily bacteria — that products usually need to find alternative sources of calcium offer a health benefit to the human body. They are often referred digestive since milk is a primary source of this important bone-building to as “good” or “friendly” bacteria based on their beneficial mineral. Although additional measures may need to be taken, activity in the intestinal tract. digestive a complete multivitamin can be a great way to promote Under normal conditions, the human digestive tract is home to optimal nutrient status in the face of digestive complications. a variety of bacteria — some “friendly” and some “unfriendly.” Talk to your healthcare professional about a formula that is The lactic-acid producing bacteria, including the Lactobacillus most appropriate for you. Although additional measures may and Bifidobacterium species, have been found to benefit the need to be taken, a complete multivitamin can be a great way intestinal environment and support healthy digestion and to promote optimal nutrient status in the face of digestive nutrient absorption. Unfortunately, the presence and activity of complications. Talk to your healthcare professional about a “unfriendly” bacteria can sometimes wreck havoc on intestinal formula that is most appropriate for you. balance and lead to diarrhea and other digestive disturbances. Prebiotics To maintain healthy digestion, consumption of probiotic ingredients may help. Prebiotics are nondigestible and nonabsorbable foods that promote the growth and/or activity of the beneficial When it comes to dietary sources, yogurt and fermented foods probiotic bacteria in the intestinal tract. As a result, prebiotic like miso and tempeh are recommended because they contain ingredients also contribute to the health of the intestinal naturally occurring live bacteria. If these items aren’t a part of system by way of keeping probiotic organisms alive and well. your regular diet, dietary supplements containing live probiotic Inulin and oligofructose — soluble fibers naturally found in ingredients are an equally great way to restore and maintain a a variety of fruits and vegetables, such as bananas, yams, healthy intestinal environment and promote optimal digestive chicory root, garlic and leeks — have been classified as health and nutrition.1,2 prebiotic ingredients based on their ability to resist digestion

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12ST0153_Answers_Brochure_Vitamins_v6.indd 28-29 4/6/12 2:34 PM heart

Vitamin D The rise of vitamin D inadequacy among Americans has prompted researchers to explore additional areas of health that How do I take care of my heart? may be affected by vitamin D insufficiency. The area of intestinal The heart is needed to deliver oxygen to the muscles and health, specifically colon health, is one that has received much transport essential nutrients to your cells. If the heart is damaged, attention. In fact, published studies have found an inverse its ability to carry out these roles and responsibilities may decline. relationship between blood levels of vitamin D and the risk of colon-related health concerns. As a result, the healthcare Engaging in regular physical exercise and eating a nutritious professional community encourages patients to have their diet are factors you can control when promoting a healthy heart. vitamin D levels tested and to ensure adequate vitamin D status Following an ideal diet can be a challenge at times, so you may through fortified foods, nutritional supplements and safe sun want to consider starting an appropriate supplement program. digestive exposure. A daily vitamin D supplement can be a great way to Dietary supplements can be a great way to support your promote optimal intestinal health.3,4 nutritional needs by filling the nutrient gaps that may exist. The nutrients discussed in this booklet include Nutrient Suggested use Multivitamin Up to 2,500 mg per day • Coenzyme Q10 • Multivitamins Prebiotic Follow the label instructions and talk to your doctor about incorporating prebiotic ingredients into your diet, • Omega-3 fatty acids particularly when following a probiotic regimen. • Plant sterols and stanols Probiotic Follow the label instructions and talk to your doctor about the probiotic that is right for you.

Vitamin D 1,000-2,000 IU per day for adults • Higher amounts may be taken under a doctor’s supervision, especially if deficiency is present

REMEMBER: Please consult with your doctor before beginning any dietary supplement program or for specific concerns regarding your health condition or prescription medication.

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12ST0153_Answers_Brochure_Vitamins_v6.indd 30-31 4/6/12 2:34 PM Coenzyme Q10 CoQ10 is an antioxidant and is required for proper function of foods you eat, then a daily fish oil supplement can be a great many organs and chemical reactions in the body, including the source as well. For vegetarians, flaxseed oil provides an heart. Free radicals are compounds that can harm your cells omega-3 fatty acid known as alpha-linolenic acid (ALA), which and negatively impact the way those cells function in the body. partially converts to EPA and DHA in the body. ALA is also Therefore, it is important to include antioxidant nutrients in your found in walnuts, almonds, avocados and other plant-based diet, such as CoQ10. While CoQ10 is rare, statin drugs used to foods and oils. Supportive but not conclusive research shows lower cholesterol can adversely affect blood CoQ10 levels. If you that consumption of EPA and DHA omega-3 fatty acids may think you may be at risk of low CoQ10 levels, talk to your doctor reduce the risk of coronary heart disease. about taking a CoQ10 supplement. To promote heart health or restore normal levels for those on statin drugs, a daily CoQ10 Plant sterols and plant stanols supplement can be useful. These compounds have been clinically shown to naturally lower cholesterol levels by preventing the absorption of Multivitamins 2,3 cholesterol found in your diet. The National Cholesterol heart A daily multivitamin contributes to your nutritional status by filling Education Program (NCEP) of the National Institutes of Health heart the vitamin and mineral gaps that may exist in your diet. A daily recommends 2,000 mg per day of these plant compounds multivitamin may be sufficient for some people, but for others from fortified foods or supplements. a multivitamin may lack a needed nutrient or may not provide enough of a nutrient. In such cases, extra supplements may be necessary. Omega-3 fatty acids Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are two omega-3 fatty acids that have been extensively studied for their beneficial role in cardiovascular health. The American Heart Association suggests 500 mg of EPA and DHA per day for healthy adults and 1,000 mg per day for adults with documented heart health concerns.1 Fatty fish like salmon, anchovies, sardines and halibut are some of the strongest sources of EPA and DHA. If you cannot get enough EPA and DHA through the

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12ST0153_Answers_Brochure_Vitamins_v6.indd 32-33 4/6/12 2:34 PM Given that plant sterols and stanols compete with dietary cholesterol for absorption in the gut, it is recommended to take a sterol and stanol supplement 15 to 30 minutes before a meal. For the greatest effect, it is advised to take sterol and stanol supplements before meals that contain cholesterol-containing foods like meat, poultry, cheese and eggs.

Nutrient Suggested use Antioxidant Vitamin C: 250-1,000 mg per day10 vitamins C and E Vitamin E: 200-400 IU per day11

Coenzyme Q10 100-200 mg per day for adults8,9 • Higher amounts may be taken under a doctor’s supervision

Omega-3 fatty acids 500 mg of EPA/DHA per day for healthy individuals EPA and DHA 1,000 mg of EPA/DHA per day for individuals with or documented heart conditions*

heart Omega-3 fatty acid 500-1,500 mg per day of ALA as directed by your ALA healthcare provider

Plant sterols The National Cholesterol Education Program of the and stanols National Institutes of Health (NIH) recommends 2,000 mg per day of plant sterols and stanols as part of a heart-healthy diet Vitamin D 1,000-2,000 IU per day for adults • Higher amounts may be taken under a doctor’s supervision, especially if deficiency is present 400 IU per day for infants, children and adolescents as recommended by the American Academy of Pediatrics7

*High levels of EPA/DHA must be monitored closely and taken under a doctor’s supervision.

REMEMBER: Please consult with your doctor before beginning any dietary supplement program or for specific concerns regarding your health condition or prescription medication.

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12ST0153_Answers_Brochure_Vitamins_v6.indd 34-35 4/6/12 2:34 PM Offer good only at Walgreens Offer good only at Walgreens $ 5off It’s never too $ Coromega® Omega 3 “early to take steps Squeeze 30 pack 2off CONSUMER: Limit one coupon per to support your Any BluScience™ purchase as specified on the face of this coupon. No other coupon may be used in heart health. Chromadex products conjunction with this coupon. RETAILER: ® This coupon good only on the purchase We will reimburse you the face value of Nature Made is a of BluScience™ products. Any other use this coupon plus 8¢ handling, provided it constitutes fraud. Coupon not transferable. is redeemed by a consumer at the time of Limit one coupon per purchase. Coupon purchase on the brand specified. Coupons great way to start. cannot be combined with other coupons not properly redeemed will be void and held. or offers. Customer must pay sales tax. Reproduction of this coupon is expressly RETAILER: ChromaDex, Inc. will reimburse prohibited. (Any other use constitutes fraud.) ” you the face value of this coupon, plus 8¢ Invoices proving purchase of sufficient stock within the past 90 days to cover coupons John Probst, RPh if submitted in compliance with the terms Pharmacist/Manhattan Beach, CA of this offer. Valid only if redeemed by presented for redemption must be shown distributors of our merchandise or anyone upon request. Mail to: CMS Dept. 89269, The specifically authorized by ChromaDex, Inc. Coromega Company, 1 Fawcett Drive, Del Cash value 1/20¢. Mail to: ChromaDex, Inc., Rio, TX 78840. Cash value 1/100. Void where 10005 Muirlands Blvd., Suite G, Irvine, CA taxed or restricted. LIMIT ONE COUPON PER 92618-2538. Expires 5/1/13. ITEM PURCHASED. For CMS inquires please call 800-285-7602. Expires 5/1/13.

Offer good only at Walgreens Offer good only at Walgreens

$ $2off 2off Feosol® Original Any Nature Made® or Natural Release product Iron Supplement Coupon good only in USA for product/ CONSUMER: Void if sold, copied, transferred, quantity indicated. LIMIT ONE COUPON PER altered, or auctioned. Only one coupon PURCHASE. Any other use constitutes fraud. is redeemable per purchase and only on Void if copied, transferred, sold, or where specified product(s) and size(s). You pay Visit NatureMade.com to hear more from real prohibited, restricted or taxed. Consumer any sales tax. RETAILER: We will reimburse pays sales tax. Retailer: Pharmavite LLC you for the face value of the coupon plus 8 pharmacists and for additional money saving coupons. will reimburse an authorized retailer of our cents if submitted in compliance with our product the face value of this coupon plus 8¢ redemption policy, available upon request. handling if submitted in compliance with our Cash value 1/20 cents. Mail to Meda redemption policy, available upon request. Consumer Healthcare Inc., PO Box 880414, El Paso, TX 88588-0414. Limit one coupon Mail to CMS Dep’t #31604, Pharmavite 1 † This statement has not been evaluated by the Food and Drug Administration. Fawcett Drive, Del Rio, TX 78840. Cash value per purchase. Meda Consumer Healthcare These products are not intended to diagnose, treat, cure or prevent any disease. .001¢. © 2012 Pharmavite. Expires 5/1/13. Inc. ©2012. Expires 5/1/2013.

12ST0153_Answers_Brochure_Vitamins_v6.indd 36-37 4/6/12 2:34 PM immune

Echinacea Echinacea is one of the most popular herbs in the United States, What supplements can help my immune taken by many people when they are not feeling their best. system function best? Echinacea is thought to benefit immune health, particularly when unwanted symptoms are present or when you feel at The immune system mission is simple: recognize free radicals risk of becoming sick.2 Even though echinacea is recognized and eliminate them. When you have a healthy immune system, as a safe herbal supplement when taken as directed, it is still your body is doing a good job of fighting off invaders and recommended that you check with your doctor about your keeping your body’s health strong. supplement use. This is especially important if you are taking Vitamin C has been shown to have a positive effect on the medications, are pregnant or breastfeeding or have a diagnosed body’s immune cells. Here are other important nutrients that auto-immune condition. 1 can support a healthy immune system: Multivitamins • Echinacea A daily multivitamin contributes to your nutritional status by • Multivitamins filling the vitamin and mineral gaps that may exist in your diet. • Vitamin C A daily multivitamin may be sufficient for some people, but for • Vitamin E others a multivitamin may lack a needed nutrient or may not • Zinc provide enough of a nutrient. In such cases, extra supplements immune may be necessary. Vitamin C Vitamin C has been found to protect the integrity of cells and stimulate the production and function of white blood cells.1 As a powerful antioxidant, vitamin C helps fight against free radicals in the body. Free radicals are compounds that can harm your healthy cells — including your immune fighting cells — and negatively impact the way those cells function in the body. Vitamin C is abundant in many fruits and vegetables and can also be obtained in supplement form.

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12ST0153_Answers_Brochure_Vitamins_v6.indd 38-39 4/6/12 2:34 PM Offer good only at Walgreens Offer good only at Walgreens

Vitamin E Many studies show that vitamin E plays an important role in the maintenance of a healthy immune system. Vitamin E also $ protects against free-radical damage. Environmental pollution, $ the sun’s ultraviolet rays, cigarette smoke and certain health 1off Any 30 ct. box 1off conditions are all capable of triggering free-radical damage in ® of Emergen-C® vitafusion our bodies. vitamin drink mixes B Complex Gummy Vitamins 150 ct. RETAILER: We will reimburse you the face Zinc value of this coupon plus 8¢ handling, Retailer: Northwest Natural Products provided it is redeemed by a consumer at will reimburse you the face value of this the time of purchase on the brand specified. coupon plus 8 cents handling for coupons Zinc is needed for your body to carry out its normal immune Coupons not properly redeemed will be redeemed in accordance with this offer. response when invaders attack. Zinc is involved in additional void and held. Reproduction of this coupon Invoices proving purchase of sufficient is expressly prohibited (ANY OTHER USE stock to support coupon submissions must aspects of your health, including growth and development, CONSTITUTES FRAUD.) MAIL TO: Alacer be provided upon request. Consumers are Corp., CMS Dept #76314, One Fawcett Drive, limited to one coupon per purchase and nervous system function, antioxidant activity and reproduction. Del Rio, TX 78840. Cash Value .001¢. Void are responsible for all taxes. Cash value is where prohibited, taxed or restricted by law. .0001 cents. Send all coupons to: NUNO/ LIMIT ONE COUPON PER ITEM PURCHASED. Universal, P.O. Box 222510, Hollywood, FL © 2012 Alacer Corp. All Rights Reserved. 33022-2510. Expires 5/1/13. Nutrient Suggested use Expires 5/1/13. Offer good only at Walgreens Offer good only Echinacea 350 mg aerial parts, four times per day at Walgreens Vitamin C 500-1,000 mg per day Vitamin D 1,000-2,000 IU per day for adults $ • Higher amounts may be taken under a doctor’s off

immune supervision, especially if deficiency is present 4 SLO-NIACIN® $ 400 IU per day for infants, children and adolescents as Dietary Supplement 1off ® recommended by the American Academy of Pediatrics2 100 ct. Tablets, 500 mg. Applied Nutrition Supplements Vitamin E 200-400 IU per day RETAILERS: We will reimburse you the face value of this coupon plus 8¢ handling provided Consumer: Redeemable at retail locations Zinc 8-30 mg per day you and the consumer have complied with the only. Not valid for online or mail-order terms of this offer. Invoices proving purchases purchases. Retailer: Irwin Naturals will REMEMBER: Please consult with your doctor before beginning any dietary supplement of sufficient stock to cover presented coupons reimburse you for the face value plus 8 must be shown on request. Any other program or for specific concerns regarding your health condition or prescription medication. (cents) handling provided it is redeemed application may constitute fraud. Coupon by a consumer at the time of purchase on void where prohibited, taxed, or restricted. the brand specified. Coupons not properly Consumer must pay any sales tax. Cash redeemed will be void and held. Reproduction value .001¢. Reproduction of this coupon is by any party by any means is expressly expressly prohibited. Mail to: Upsher-Smith prohibited. Any other use constitutes fraud. Laboratories, Inc. #00245, One Fawcett Drive, Irwin Naturals reserves the right to deny Del Rio, TX 78840. This coupon is immediately reimbursement (due to misredemption redeemable for $4.00 off the retail price activity) and/or request proof of purchase of Slo-Niacin® Tablets (500 mg). Only one for coupon(s) submitted. Mail to: CMS Dept. coupon per each purchase made by 5/1/13. 10363, Irwin Naturals, 1Fawcett Drive, Del Applies only in U.S.A. Void where prohibited by Rio, TX 78840. Cash value: .001 (cents). Void law. Upsher-Smith Laboratories, Inc., reserves where taxed or restricted. ONE COUPON PER the right to rescind, revoke, or amend this PURCHASE. Not valid for mail order/websites. 40 offer without notice. Expires 5/1/13. Retail only. Expires 5/1/13.

12ST0153_Answers_Brochure_Vitamins_v6.indd 40-41 4/6/12 2:34 PM prenatal health

What steps should I take to help ensure a healthy pregnancy? If you are pregnant or are hoping to conceive, it is important to receive the best prenatal care by seeing your OB/GYN regularly and taking steps to ensure the health of you and your baby. A healthful, balanced diet that includes plenty of whole fruits and vegetables, whole grain products, lean protein and healthy fats will help ensure good health for you and your baby throughout pregnancy. The dietary choices you make during this time will have a powerful effect on giving your baby a strong start in life. Read on to learn more about how vitamins and minerals help support your health during pregnancy: • Prenatal multivitamins • Calcium • Folic acid • Iron • Omega-3 fatty acids • Supplemental algae • Vitamin C • Vitamin D • White fatty fish

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12ST0153_Answers_Brochure_Vitamins_v6.indd 43 4/6/12 2:34 PM Prenatal multivitamins Iron These nutrients are critical during pregnancy, and support During pregnancy, a woman’s iron needs increase. In fact, they are your needs and those of your growing baby. Pregnancy places nearly twice those of a nonpregnant woman. To ensure adequate a higher demand on the body, and increases the amount of iron status, it is important to consume iron-rich foods such as nutrients required. Adequate amounts of essential vitamins and lean meat, poultry, dried fruits and iron-fortified cereals. Prenatal minerals and other key nutrients during pregnancy are vital to formulas and iron supplements can also help fulfill the high demand the development of your baby, and for your health too! for iron during pregnancy and the post partum period. Omega-3 fatty acids To help avoid some common side effects from a prenatal multivitamin such as queasiness or stomach upset, take your The omega-3 fatty acid docosahexaenoic acid (DHA) is prenatal supplement with a substantial meal or snack. Some women especially important because it promotes the healthy growth may benefit from chewing gum or sucking on a hard candy after 2 taking their prenatal, while others may have better luck with taking and development of your baby’s brain, eyes and nervous system. it at night with an evening snack. Mothers of breast-fed infants should be aware that breast milk is not naturally high in DHA. If you choose to breastfeed your child, ensure you have adequate DHA in your Calcium diet or through supplementation. Calcium’s primary responsibility during pregnancy is to maintain strong maternal bone health and promote healthy fetal bone Supplemental algae development. Calcium also helps your circulatory, muscular and Supplemental algae oil is a fish-free way to get DHA. Also, alpha nervous systems to run normally.1 linolenic acid (ALA) found in flaxseed oil, canola oil and walnuts Folic acid is an omega-3 fatty acid that is partially converted to DHA in

the body. prenatal Folic acid plays a critical role in the formation and development Vitamin C

prenatal prenatal of a baby’s brain and spine — an important process that occurs during the initial three to four weeks of pregnancy. If you have Vitamin C promotes the absorption of non heme iron, a form a diagnosed malabsorption concern or any condition that may of iron found in plants and fortified foods. Taking a vitamin C limit your dietary intake of folic acid, you may benefit from a supplement with your iron supplement or eating citrus fruits with folic acid supplement. Be sure to talk to your doctor about safe your iron-fortified cereals can promote optimal absorption of supplement use. non heme iron. This is particularly applicable for women who are vegetarian, or vegan.

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12ST0153_Answers_Brochure_Vitamins_v6.indd 44-45 4/6/12 2:34 PM Vitamin D For pregnant women, maintaining sufficient vitamin D status is critical for proper fetal development, especially brain and Nutrient Suggested use for prenatal health immune system development. Vitamin D also is important for Prenatal multivitamins 1 per day or as directed by your healthcare provider keeping your bones and your baby’s bones healthy and strong. Furthermore, research suggests adequate maternal intake Calcium 1,000 mg per day in two divided doses of vitamin D during pregnancy has been associated with a Folic acid 600 mcg per day during pregnancy 500 mcg per day during lactation decreased risk of childhood wheezing and eczema.4,5 To find

out your current vitamin D levels, talk to your healthcare provider Iron 27 mg per day or as directed by your healthcare provider

about the 25-hydroxy vitamin D test. Most prenatal vitamins Omega-3 fatty acids DHA: at least 200 mg per day or as directed by your (DHA) healthcare provider. Some experts recommend don’t contain optimal amounts of vitamin D. In addition to your 300-600 mg per day

prenatal vitamin, drink vitamin D-fortified low-fat milk and other Vitamin D 1,000-2,000 IU per day or as directed by your healthcare provider calcium-rich foods containing vitamin D. If you don’t drink or eat calcium-rich foods, talk to you healthcare provider about REMEMBER: Please consult with your doctor before beginning any dietary supplement program or for specific concerns regarding your health condition or prescription medication. calcium and vitamin D supplements. White fatty fish Nutrient Suggested use for children’s health While fatty fish are the best dietary sources of omega-3 fatty Children’s multivitamins 1 per day or take as directed by pediatrician acids, women of child-bearing age and pregnant women are Calcium Children advised to avoid certain fish that may have a high content of 1 to 3 years: 500 mg per day /4 to 8 years: 800 mg per day methylmercury, a compound that can affect the development Adolescent male 3 9 to 13 years: 1,300 mg per day /1 4 to 1 8 years: 1,300 mg per day of the baby’s nervous system. Fish to avoid include shark, prenatal Adolescent female swordfish, king mackerel and tilefish. Cooked fish, such as 9 to 13 years: 1,300 mg per day /1 4 to 1 8 years: 1,300 mg per day

prenatal prenatal salmon, have a stronger safety profile for pregnant women; Choline Children in general, up to 12 ounces per week of cooked fish may be 1 to 3 years: 200 mg per day /4 to 8 years: 250 mg per day consumed. Fish oil supplements are also available to help meet 9 to 13 years: 375 mg per day Adolescent male the recommendations for DHA. Your primary healthcare provider 1 4 to 1 8 years: 550 mg per day can help you choose a safe omega-3 supplement during Adolescent female pregnancy and lactation. 1 4 to 1 8 years: 400 mg per day Fluoride As directed by a pediatrician or dentist Iron Children 1 to 3 years: 7 mg per day /4 to 8 years: 10 mg per day Adolescent male 46 9 to 13 years: 8 mg per day /1 4 to 1 8 years: 11 mg per day 47 Adolescent female 12ST0153_Answers_Brochure_Vitamins_v6.indd 46-47 9 to 13 years: 8 mg per day /1 4 to 1 8 years: 15 mg per da4/6/12y 2:34 PM Offer good only at Walgreens Offer good only at Walgreens

$ $1off 1off Any Flintstones™ Similac® Prenatal Complete Multivitamins Vitamins Dietary & Gummies products Supplement product CONSUMER: Void if sold, copied, tranferred, altered, or auctioned. Only one coupon LIMIT 1 COUPON PER PRODUCT SPECIFIED. is redeemable per purchase and only on Cannot be combined with other offers. Void if specified product(s) and size(s). You pay any altered, reproduced, copied, sold, transferred, sales tax. RETAILER: You are authorized to taxed, restricted or prohibited by law. Good act as our agent and redeem this coupon only in USA and territories. Cash value at face value on specified product(s). We 1/100¢. Customer pays sales tax. Retailer/ will reimburse you for the face value of this Clearinghouse: By submitting, you agree to coupon plus 8¢ if submitted in compliance Abbott’s Coupon Redemption Policy. Abbott with the Bayer HealthCare LLC Coupon will reimburse you face value of coupon (or Redemption Policy, incorporated herein by actual retail price of item if less) plus 8¢ reference. USE NOT CONSISTENT WITH handling. Send to CMS Dept 70074, ABBOTT THESE TERMS MAY CONSTITUTE FRAUD NUTRITION, 1 Fawcett Dr., Del Rio, TX 78840. AND MAY VOID ALL COUPONS SUBMITTED. Pharmacists/Retailers: Coupon not valid for Send coupons to: Bayer HealthCare LLC, P.O. product reimbursed, in whole or part, under Box 880319, El Paso, TX 88588-0319. Cash Medicare, Medicaid or similar federal or state value, 1/20th of1¢. Good only in U.S.A. © government programs. Expires 5/1/13. 2012 Bayer HealthCare LLC. Expires 5/1/13.

Offer good only at Walgreens Offer good only at Walgreens

$1off SpongeBob® SquarePants $ Gummies Multivitamin 240 ct. Consumer: Limited one coupon per customer per offer. Expires 4off 5/1/2013. Manufacturer coupon good only at Walgreens. Consumer Feosol® Complete pays any sales tax. Retailer: International Vitamin Corporation will reimburse you for face value of this coupon plus 8 ¢ handling. Iron Supplement Coupons not properly redeemed will be void and held. CONSUMER: Void if sold, copied, transferred, Reproduction of this coupon is expressly altered, or auctioned. Only one coupon prohibited. Cash value 1/100 of 1 cent. is redeemable per purchase and only on Mail to: Sponge Bob Gummi $1 Coupon, specified product(s) and size(s). You pay PO Box 5098, Clinton, IA 52736-5098. any sales tax. RETAILER: We will reimburse SpongeBob SquarePants ©2011 Viacom you for the face value of the coupon plus 8 International Inc. All Rights Reserved. cents if submitted in compliance with our These statements have not been evaluated by the Food and Drug Administration. These products are not Nickelodeon, SpongeBob SquarePants and redemption policy, available upon request. intended to diagnose, treat, cure or prevent any disease. all related titles, logos and characters are Cash value 1/20 cents. Mail to Meda trademarks of Viacom International Inc. Consumer Healthcare Inc., PO Box 880414, WARNING: Accidental overdosage of iron-containing products is a leading cause of fatal poisoning in children SpongeBob SquarePants created by El Paso, TX 88588-0414. Limit one coupon under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison Stephen Hillenburg. www.nick.com. per purchase. Meda Consumer Healthcare control center immediately. Expires 5/1/2013. Inc. ©2012. Expires 5/1/2013.

4095-0212A1701a_Feosol-Walgreens-Insert_022312_r11_OL.indd12ST0153_Answers_Brochure_Vitamins_v6.indd 48-49 1 2/27/2012 10:07:31 AM 4/6/12 2:34 PM children’s health

Children’s multivitamins Much like a formula for adults, a daily children’s multivitamin can help fill the gaps that may exist in a child’s diet. Purchase, How do vitamins support my child’s health? prepare and provide healthful foods, and show your child that As your child grows, vitamins and minerals play a big part in you eat and enjoy them, too. Encourage fruits, vegetables, building and maintaining health. They help with many important dairy, whole grains and lean meats when you talk about things, including bone and brain development, energy production “everyday” foods, and sweets and sugars when you discuss and muscle function as well as preventing tooth decay. However, foods in moderation. The key nutrients below are important knowing which vitamins you should give your child can be a elements of your child’s diet. If meeting your child’s nutritional needs is hard to do through foods alone, a children’s challenge. So, if you are unsure about your child’s nutritional multivitamin may help. and vitamin needs, talk with your pediatrician. Remember to keep vitamins out of the reach of children. Calcium The vitamins and minerals discussed in this section include Calcium is another important component of a child’s diet, • Children’s multivitamins and is necessary for building and maintaining healthy bones • Calcium • Choline • Fluoride and teeth. Children who drink milk and eat dairy products, such • Iron • Vitamin D as yogurt, ice cream and cheese, usually get enough calcium from their diet. However, some kids just don’t like milk or can’t Vegetarians may have tolerate milk due to a milk allergy. In these cases, providing a inadequate levels of this children’s multivitamin, calcium-fortified foods and juices or vital nutrient. If your child increasing your child’s intake of dark leafy greens can help may be at risk of low dietary choline, you might want to meet their needs appropriately. consider supplementation. Some children’s multivitamin Choline formulas provide choline, Choline plays an important role during the early years of child so you can support your

child’s diet and ensure development. It is used in the synthesis of key components children’s adequate levels of this necessary for healthy cell membranes called phospholipids. brain-boosting nutrient. Choline is also involved in the formation of neurotransmitters, which are important for proper brain and muscle function.7 Choline is found in foods, such as milk, eggs, liver, shrimp

50 51

12ST0153_Answers_Brochure_Vitamins_v6.indd 50-51 4/6/12 2:34 PM Nutrient Suggested use for prenatal health Prenatal multivitamins 1 per day or as directed by your healthcare provider

Calcium 1,000 mg per day in two divided doses

Folic acid 600 mcg per day during pregnancy 500 mcg per day during lactation

Iron 27 mg per day or as directed by your healthcare provider

Omega-3 fatty acids DHA: at least 200 mg per day or as directed by your (DHA) healthcare provider. Some experts recommend 300-600 mg per day

Vitamin D 1,000-2,000 IU per day or as directed by your healthcare provider

and peanuts. Children who do not consume milk or eggs, who have a peanut or shellfish allergy, or who are vegetarian, Nutrient Suggested use for children’s health may have inadequate levels of this vital nutrient. Children’s multivitamins 1 per day or take as directed by pediatrician Calcium Children Fluoride 1 to 3 years: 500 mg per day /4 to 8 years: 800 mg per day Adolescent male Most children get enough fluoride to build healthy teeth 9 to 13 years: 1,300 mg per day /1 4 to 1 8 years: 1,300 mg per day and prevent tooth decay if they are drinking fluoridated water. Adolescent female 9 to 13 years: 1,300 mg per day /1 4 to 1 8 years: 1,300 mg per day Supplemental fluoride is not necessary for all children, especially since too much fluoride can cause staining of the teeth. Consult Choline Children 1 to 3 years: 200 mg per day /4 to 8 years: 250 mg per day your child’s pediatrician or dentist before giving your child a 9 to 13 years: 375 mg per day fluoride supplement. Adolescent male 1 4 to 1 8 years: 550 mg per day Adolescent female Iron 1 4 to 1 8 years: 400 mg per day

Iron is an essential nutrient involved in numerous bodily Fluoride As directed by a pediatrician or dentist functions, including normal growth and development, energy Iron Children production and the transportation of oxygen to the body’s 1 to 3 years: 7 mg per day /4 to 8 years: 10 mg per day tissues. Those most at risk for iron deficiency anemia are infants Adolescent male 9 to 13 years: 8 mg per day /1 4 to 1 8 years: 11 mg per day who are not given extra iron after six months of age (usually in Adolescent female the form of iron-fortified infant cereal) and adolescent girls once 9 to 13 years: 8 mg per day /1 4 to 1 8 years: 15 mg per day they begin menstruation. REMEMBER: Please consult with your doctor before beginning any dietary supplement Vitamin D program or for specific concerns regarding your health condition or prescription medication. In 2008, the American Academy of Pediatrics increased the recommended intake of vitamin D for all infants, children and adolescents to 400 I.U. per day. In its report, the AAP discussed

the rising rate of vitamin D deficiency among infants, children children’s and adolescents, and the potential risks of low vitamin D status, including Rickets (softening of the bones), and negative effects children’s children’s on heart and immune health.6

52 53

12ST0153_Answers_Brochure_Vitamins_v6.indd 52-53 4/6/12 2:34 PM Pediatricians’Pediatricians’ **** Multivitamin #1#1 RecommendedRecommended BrandBrand Multimineral Dietary Supplement

withwith CholineCholine toto supportsupport brainbrain function*function*

NoNo artificialartificial colorsccocolorscoco olol lolo oors rrsrs s oro oorrr flavorsffflflavorslllaaav avav vvoo orrss

More moms trust Flintstones™ than any 66 charactercharacter other children’s multivitamin. shapesshapes && naturalnatural flavorsflavors flintstonesvitamins.com Tropical Punch ● Watermelon Mixed Berry ● Grape ● Cherry ● Orange **For Children's Chewable Vitamins †With 50% DV more than previous formula ©2012 Viacom International Inc. All Rights Reserved. Nickelodeon, SpongeBob THE FLINTSTONES: SquarePants and all related titles, logos and characters are trademarks of Viacom International Inc. Created by Stephen Hillenburg. www.Nick.com TM & © Hanna-Barbera. (s12) *This statement has not been evaluated by the Food and Drug Administration. *This statement has not been evaluated by the Food & Drug Administration. © 2012 Bayer HealthCare LLC This product is not intended to diagnose, treat, cure, or prevent any disease. This product is not intended to diagnose, treat, cure, or prevent any disease.

12ST0153_Answers_Brochure_Vitamins_v6.indd 54-55 4/6/12 2:35 PM menopause

How can supplements help ease symptoms of menopause? In menopause, a woman’s period stops permanently. This happens when the ovaries stop making estrogen and progesterone. The natural transition to menopause can take many years. But symptoms can appear as soon as the change begins. Common symptoms include hot flashes, night sweats, trouble sleeping and vaginal dryness. Other symptoms include memory problems, physical complaints and mood changes. The changes of menopause also increase the risk for B vitamins: B6, B12 and folic acid osteoporosis, heart disease and stroke. Hormonal changes in menopause may increase the body’s Although research as not yet seen conclusive results, some levels of an amino acid called homocysteine. This can increase women use vitamins, minerals and supplements to help the risk for heart disease and stroke. Folic acid and vitamins B6 2,3 manage their symptoms. Studies of certain supplements and B12 may help lower homocysteine levels. for menopause have had varying results. If you want to take Calcium and vitamin D dietary supplements for menopause, talk with your doctor first. Together you can discuss the possible benefits and side effects Calcium and vitamin D are important for bone health. of supplements and decide which ones might be right for you. This is especially important in menopause, when the risk for osteoporosis rises. Most women should have 1,200 mg of Several vitamins, minerals and supplements might be helpful calcium a day from food and supplements. Most women should for women during menopause. These include also have 800 IU to 1,000 IU of vitamin D per day. Diet and • B Vitamins: B6, B12 and folic acid sunlight provide some vitamin D. However, a supplement may • Calcium and vitamin D be needed in menopause. Ask your doctor how much calcium • Soy and vitamin D you should take, especially if you have a history • Vitamin E of kidney stones.1 menopause

menopause 56 57

12ST0153_Answers_Brochure_Vitamins_v6.indd 56-57 4/6/12 2:35 PM The COMPLETE Soy Soy contains estrogen-like compounds called isoflavones. BENEFITS Soy proteins might also lower the risk for osteoporosis and heart ® disease. Some women should be cautious when taking soy, of Centrum including those with a history of estrogen-receptive cancer or those taking medications that increase estrogen levels.4,5,10 Vitamin E Vitamin E is an antioxidant. It is thought to relieve inflammation and support immune systems. It is found in many foods. It is also available as a supplement.7,8

Supplement Suggested use B Vitamins: Vitamin B6: Age 19 to 50, 1.3 mg per day B6 and B12 Age 51+, 1.5 mg per day a,10 Vitamin B12: 2.4 mcg a,11 Folic acid Because folic acid (folate) from natural foods is absorbed by the body differently than folic acid in supplements, talk to your doctor about the best amount for you.

Calcium and Calcium: 1,200 mg per day from food and supplements1 vitamin D Vitamin D: 800 IU per day to 1,000 IU per day to prevent osteoporosis1 Soy 25 grams per day of soy protein to reduce the risk of heart disease 7 Vitamin E 22.4 IU a,9

a These are the recommended dietary allowances for general health. Ask your doctor if you need a different amount during menopause. Specially Formulated for Women & Men

100-200 mg. per day for adultsa,9

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12ST0153_Answers_Brochure_Vitamins_v6.indd 60-61 4/6/12 2:35 PM DO NOT PRINT THIS SLUG Fn: 12-NB-1058-AD-LAY Introducing Delicious Pu: 12-NB-1035-AD-LAY SHAKE UP DO NOT PRINT THIS SLUG ® Supplement Your Diet Nature’s Bounty Publication: Natures Bounty WAG Vit Brochure ® Fn: 12-SD-1036-AD-LAY May 2012 Ref: 12-SD-1005-AD-LAY Complete Protein Page: 1the Sundown Naturals Way! YOUR Publication: Walgreens 5 x 7 Trim Size: 5 x 7” Page: 1 & Vitamin Live Area: 4.5 x 6.5” Bleed Area: 5.25 x 7.25 Live/Trim: 5” x 7” ROUTINE. Bleed: 5.25” x 7.25” Shake Mix. Layout: 3/7/12 mva/rj Rev: 3/8/12 mva/rj Layout: 3/13/12 dr/rj Shake things up with the luscious, nutrient- Rev: 3/9/12 mva/rj Revise: 3/13/12, 2pm dr/rj Rev: 3/14/12 mva/rj Revise: 3/13/12, 4pm dr/rj rich shakes that are anything but routine. Rev: 3/15/12 mva/rj Appr’d: 3/14/12 dr/rj Appr’d: 3/15/12 mva/rj Nature’s Bounty Complete Protein & Vitamin Images: ® Spanish Translation: 12-SD-1036-bgd1.tif Miriam Alvarez Shake Mix is packed with protein and Leaf.psd - Usage rights purchased Products: from istock Extended Licence - fiber, plus essential vitamins, • Choc prot shake: 50875 Autumn yellow leaf - • Van prot shake: 50874 File #: 17618384 140 credits - $255.50 antioxidants, electrolytes, prebiotics and By TA 12-15-11 Images: SundownFacebookBasket.psd probiotics—important for your body.* 12-NB-1058-AD-ART 1.psd Products: Choose from rich Chocolate or Shake Pour Splash book SD Acidiphilus - 017746L-RF-04F (200cc) (in house photo shoot): SD Fish Oil - 012999-RF-09J (625cc) creamy Vanilla… • Big shake pour: 077 Chocolate001 SD Vit D3 - 036245-RF-00A (100cc) SD Melatonin - 015750-RF-00A (150cc) and get shaking now. Fonts: SD Biotin - 018545-RF-03D (100cc) Futura BradleyHand ITC Fonts: Florens Frutiger Helvetica Helvetica ™ ITC Zapf Dingbats Perfect for Every Body Colors: CMYK Colors: Many of our products are… CMYK Printed @ 100% �� Printed @ 100% VERSIONFREE 1 OF Gluten & Wheat ��FREE OF Artificial Sweeteners, �� FREE OF Dairy & Lactose Flavors & Colors ENGLISH VERSION

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0030768-400493 4/6/12 2:35PM References: Digestive health 1 Douglas LC, & Sanders ME. (2008). Probiotics and Prebiotics in Dietetics Practice. Beauty J Am Diet Assoc, 108, 510-521. 1 Greul AK, Grundmann JU, Heinrich F, Pfitzner I, Bernhardt J, Ambach A, 2 Collins MD, & GR. (1999). Probiotics, prebiotics and synbiotics: approaches for � Biesalski HK, Gollnick H. (2002). Photoprotection of UV irradiated human skin: modulating the microbial ecology of the gut. Amer J of Clin Nutr, 69, 1052s-1057s. an antioxidative combination of vitamins E and C, carotenoids, selenium and 3 Garland CF, Garland FC, Gorham ED, Lipkin M, Newmark H, Mohr SB, & Holick MF. (2006). Web Exclusive Vitamin Offers proanthocyanidins. Skin Pharmacol Appl Skin Physiol.,15, 307-15. The Role of Vitamin D in Cancer Prevention. Amer Journal of Public Health, 96, 252-261. 2 Zhao JF, Zhang YJ, Jin XH, Athar M, Santella RM, Bickers DR, & Wang ZY. (1999). 4 Lappe JM, Travers-Gustafson D, Davies KM, Recker RR, & Heaney RP. 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National Center for Complementary and Alternative 2003;26:1147-1152. Medicine. http://nccam.nih.gov/health/menopause/menopausesymptoms.htm. 4 Rozendaal RM, et al. Effect of glucosamine sulphate on joint space narrowing, pain Accessed January 17, 2012. and function in patients with hip osteoarthritis; subgroup analyses of a randomized 6 Soy. MedlinePlus. http://www.nlm.nih.gov/medlineplus/ency/article/007204.htm. • Thousands of vitamins and supplements controlled trial. Osteoarthritis Cartilage 2009;17:427-32. Epub 2008 Oct 9. Accessed January 19, 2012. 5 Herrero-Beaumont G, Ivorra JA et al. Glucosamine sulfate in the treatment of knee 7 Pros and cons for treatment of menopause symptoms. The Hormone Foundation. you won’t find in stores osteoarthritis symptoms: a randomized, double-blind, placebo-controlled study http://www.hormone.org/Menopause/pros_and_cons.cfm. 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Long-chain omega-3 fatty acid supply in pregnancy and lactation. willow bark extract: a randomized double-blind study. Am J Med 2000;109:9-14. Curr Opin Clin Nutr Metab Care 2008;11:297-302. 9 Chrubasik S, Kunzel O, et al. Potential economic impact of using a proprietary 3 U.S. Food and Drug Administration and Center for Food Safety and Applied Nutrition. • Everyday Free Shipping on orders of $25 or more, willow bark extract in outpatient treatment of low back pain: an open 4 Miyake Y. et al. Dairy food, calcium, and vitamin D intake in pregnancy and wheeze non-randomized study. Phytomedicine 2001;8:241-251. and asthma in infants. Eur Respir J. 2009 Oct 19. [Epub ahead of print] plus free in store returns* 10 Kalman DS, et al. Effect of a natural extract of chicken combs with a high content 5 Devereux G. et al. Maternal vitamin D intake during pregnancy and childhood wheezing. of hyaluronic acid (Hyal-Joint®) on pain relief and quality of life in subjects with Am J Clin Nutr. 2007 Mar;85(3):853-9. knee osteoarthritis: a pilot randomized double-blind placebo-controlled trial. 6 Wagner CL & Greer FR. (2008) Prevention of Rickets and Vitamin D Deficiency in Infants, Nutr J 2008;7:3-12 Children, and Adolescents. Pediatrics, 122, 1142-1152. 7 Blusztajn, JK, et al. Synthesis of acetylcholine from choline derived from Cognitive phosphotidylcholine in a human neuronal cell line. Proc Natl Acad Sci USA Conveniently shop from anywhere at 1 Morris MC, Evans DA, Tangney CC, Bienias JL, Wilson RS. (2005) Fish 1987;84:5474-7. consumption and cognitive decline with age in a large community study.Archives of Neurology, 62(12). This publication should be used for general educational purposes only and is not intended 2 Buell JS, Scott TM, Dawson-Hughes B. Vitamin D is associated with cognitive to be a substitute for professional medical advice. Although it is intended to be accurate, Walgreens.com/Vitamins function in elders receiving home health services. J Gerontol A Biol Sci Med Sci. neither Walgreen Co., its subsidiaries or affiliates, nor any other party assumes liability » 2009 Aug;64(8):888-95. for loss or damage due to reliance on this material. Advances in medicine may cause 3 Jyme H. Schafer, MD, MPH; Thomas A. Glass, PhD. Homocysteine and this information to become outdated, invalid or subject to debate. This information is not Cognitive Function in a Population-based Study of Older Adults. J Am Geriatr Soc. intended to create any warranty, and ALL SUCH WARRANTIES, EXPRESS OR IMPLIED, 2005;53(3):381-388. INCLUDING ANY WARRANTY OF FITNESS FOR A PARTICULAR PURPOSE, ARE HEREBY 4 Cipolli C, & Chiari G. (1990) Effects of L-acetylcarnitine on mental deterioration in DISCLAIMED. If you are in need of immediate medical attention or have a medical *Restrictions apply. Learn more online. the aged: initial results. Clin Teri, 132, 479-510. question, contact your medical professional.

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