The NIH Record U.S. Department January 21 National of Health 1981 Institutes and Vol. XXXIII of Human Services No. 2 Health

37 Senior Staff Members at NIH Receive Bonuses for Outstanding Performance

Dr. Samuel Schwartz DRG A total of 37 Senior Executive Service staff Dr. Maxine Singer NCI at NIH have received bonuses ranging from Dr. Louis Sokoloff NIMH $3,000 to $10,000. Dr. George Todaro NCI Mr. William Weiss NINCDS HHS Secretary Patricia Roberts Harris an­ Dr. Marian Yarrow NIMH nounced on Jan. 2 that she had selected 100 Boards Make Recommendations members of the Department's Senior Executive Service to receive awards for Six NIH performance review boards outstanding performance. These are the provided NIH Director Dr. Donald S. first bonuses to be awarded by HHS under Fredrickson with their recommendations on the CiviI Service Reform Act of 1978. final performance appraisal ratings and nominations for bonuses. Awardees Listed Dr. Fredrickson reviewed these recom­ NIH staff members selected were: mendations, and submitted those nomina­ Dr. Christian Anfinsen NIAMDD tions to PHS and the Department's Execu­ Dr. Roscoe Brady NINCDS tive Resources Management Council. Dr. Robert Cohen NIMH Dr. Sheldon Cohen NIAID Selection Process Rigorous Dr. David Davies NIAMDD Dr. Igor Dawid NCI Secretary Harris emphasized that the Dr. Carl Douglass DRG Dr. Murray Eden DRS process for selection of award recipients Dr. Edward Evarts NIMH and determination of the dollar amount of U.S. Senator Richard S. Schweiker (R-Pa.) was Dr. Gary Felsenfeld NIAMDD Secretary-designate of the Department of Dr. Martin Gellert NIAMDD each award was extremely thorough and Health and Human Services as the Record went Dr. Clarence Gibbs NINCDS rigorous. to press.As ranking Republican on both the Dr. Eli Glatstein NCI Dr. Suzanne Hurd NHLBI Each SES member in the Department re­ Senate Labor and Human Resources Committee Mr. Howard Kettl cc and the Labor-Health and Human Services Ap­ Dr. Edward Korn NHLBI ceived an initial performance appraisal from propriations Subcommittee, he worked in Dr. Paul Kornblith NINCDS his or her supervisor based upon the objec­ Dr. Robert Levy NHLBI tives and standards spelled out in the indi­ sponsoring legislation to combat diabetes, Dr. Mort] mer Lipsett cc cancer, heart disease, sickle cell anemia, and Dr. George Martin NIDR vidual's performance plan. lead paint poisoning. Other major health con­ Mr. Joseph Naughton DCRT NIAID These appraisals were reviewed by per­ cerns include: health care reform, preventive Dr. Franklin Neva Dr. Marshall Nirenberg NHLBI formance review boards, which were com­ health care, and blood program reform. In tes­ Dr. Marie Nylen NIDR timony before the U.S. Senate Finance Com­ Dr. Joseph Perpich OD prised of top Department career scientists mittee, Senator Schweiker said, "Better health Dr. Karl Piez NIDR and executives. Dr. William Raub OD for all our citizens has also been one of my pri­ Dr. Robert Ringler NIA Secretary Harris made the final selections mary interests as a Senator.I intend to continue Dr. Griff Ross cc my efforts in health promotion and disease pre­ Dr. Kenneth Sell NIAID based upon the nominations submitted to vention within the Department ...." Dr. Stephen Schiaffino DRG her by the council. D Carter's Budget Request for NIH Frances Davis, 'Record' Editor, For Fiscal 1982 Totals $3.8 Billion Retires From NIH

President Carter's fiscal year 1982 budget research community of a steady, substantial With this issue, Frances W. Davis, editor request for NIH is $3,848,689,000, a net in­ level of research project grant support. of The NIH Record for the past 13 years, is crease of $255 million above the 1981 level joining the record number of employees being recommended by the Administration. Renovation of the Clinical Center, begun in 1979, will continue in 1982 with $6.7 mil­ retiring from the Federal service. The 1982 request continues the stabiliza­ lion budgeted for this purpose. After reno­ Mrs. Davis, who received the NIH Direc­ tion effort begun in 1981 to provide 5,000 vations are completed in 1987, the CC will tor's award last year, has had 25 years of new and competing research project grants be fully integrated with the Ambulatory Government service. each year. In the past the number of such Care Research Facility, now nearing com­ "Mrs. Davis will be sorely missed," said grants has varied from year to year, ranging pletion. Storm Whaley, NIH Associate Director for from 3,464 in 1976 to 5,944 in 1979. Communications, OD. "She has been The request also includes $5.8 million to dedicated to the Record throughout her The continued emphasis on stabilization hire the 175 support personnel necessary to tenure. We all wish her well." in 1982 recognizes the importance to the (See BUDGET, Page 11) Published biweekly at Bethesda, Md., by the Editorial .Operations Branch, Division of Public Information, for the information of employees of the National Institutes of Health, Department of Health and Human Services, and circulated by request to writers and to researchers in biomedical and related fields. The content is reprintable without permission. Pictures may be available on request. The NIH Record reserves the right to make corrections, changes, or deletions in submitted copy in conformity with the policies of the paper and HHS.

NIH Record Office Bldg. 31, Room 2B-03, Phone 496-2125

Edllor Frances W. Davis Staff Writers William A. Reinckens Joyce F. McCarthy

Staff Correspondents CC, Barbara Smakula; DCRT, Mary Hodges; DPM, Judy Fouche; DRG, Sue Meadows; ORR, Barbara Menick; DRS, Ar­ thur F. Moore; FIC, Toby P. Levin; NCI, Patricia A. Newman; NEI, Marsha Corbett; NHLBI, Bill Sanders; NIA, Ann Dieffen­ bach; NIAID, Jeanne Winnick; NIAMDD, Linda Cross; NICHD, Pamela Driscoll; NIDR, Sally Wilberding; NIEHS, Hugh J. Lee; NIGMS, Wanda Warddell; NIMH, Betty Zubovic; NINCDS, A BASKET OF CHEER TURNS INTO A BASKET OF MONEY-The Patient Emergency Fund grew when Edith Messitte; NLM, Roger L. Gilkeson. a "basket of money" was turned over to Stanley Kissel, chief, CC Social Services Department, by R&W Gift Shop managers, who ran "a basket of cheer" raffle last month to raise money for this worthwhile cause. Over $900 was collected from employee customers. Winners of the Dec. 22 drawing were: Alene Staley, Financial Management, CC; Virginia Backora, OD, Bldg. 31; Isabel Fine, NLM, Bldg. 38A; and Dr. Earl Fisher, DRG, Westwood Bldg. In addition to the raffle money, Patient Emergency Fund $2,000 was donated in December from the Davis Plan-a long-time employee system of contribution where the amount that an employee would spend on Christmas cards is turned over to Needs Everyone's Help the Patient Emergency Fund-as well as from individual donations. The managers presented the

The Patient Emergency Fund needs raffle proceeds to Mr. Kissel. L to r are: Judy Slight, Bldg. 38; Hiltraud James, Bldg. 31; Stanley Kissel, CC; Anne Orvas, Westwood Bldg., and Rosalie Efird, CC. everyone's support to continue the human­ itarian services it has provided over the last quarter of a century. The PEF pays the unusual and unforeseen Have Flu Symptoms? expenses of some Clinical Center patients CC Asks You To Stay Away Training Tips and their relatives. Each year the fund meets the ever-increasing costs of travel, Because this is the flu season, NIH visi­ Over 100 persons responded to an edito­ lodging, and subsistence for those who tors and employees with flu symptoms rial training needs survey which was an­ cannot meet these emergency needs by should refrain from entering the hospital as nounced in the Aug. 5 Record. The survey raising money through private contribu­ a health safeguard, according to the Clinical was developed to elicit data about specific tions. Center's Infection Control Office. skills and knowledge needed to perform The need for private assistance is essen­ "There is a high risk involved for many editorial work. As a result, the Training As­ tial because these items are not covered patients if they should get influenza," sistance Branch, DPM, is offering the fol­ under regular medical care. said Dr. David Henderson, CC epidemi­ lowing courses to be held on campus: Over the years, former NIH patients and ologist. "There is presently a flu epidemic local community organizations have con­ in the Washington area so we are asking Communication Course tributed to the PEF. Besides these sources that people take extra precautions." Skills Starts Deadline of income, NIH employees have contrib­ To minimize risk, the Infection Control Principles of Editing Feb. 2 Jan. 23 uted heavily through their Recreation & Office is asking that anyone with upper res­ Intermediate Editing Mar. 16 Feb. 23 Welfare Association. Even private citizens piratory problems-fever, cough, muscle Editing of Technical not connected with NIH have given to the aches, or a runny nose-stay away from the Manuscripts Apr. 7 Mar. 17 PEF. hospital. Dr. Henderson also requests that Writing workshop Feb. 23 Feb. 2 All fund donations are tax deductible. employees with those symptoms go to the They can be dropped off at the CC Social Occupational Medical Service. In addition, other courses are: Work Department, Bldg. 10, Rm. 7D-53; For further questions regarding influenza, sent to an employee's administrative offi­ contact Dr. Henderson, 496-2209. D Office Skills cer; or can be received at one of the R&W Memory Typewriter Feb. 2 Jan. 23 gift shops at NIH. (Application Seminar) For further information, call 496-2381. D Jan. 23 Limited Tax Return Aid Available Memory Typewriter Feb. 2 (User's Seminar) Sailing Club Meets Jan. 29 Beginning Feb. 5 Small Purchase Procedures Feb. 10 Jan. 28 The first meeting of the NIH Sailing Club Tax forms, tax information, and limited Time Management for will be held on Thursday, Jan. 29, at 8 p.m., assistance in computing 1980 returns will be Secretaries Feb. 2 Jan. 23 in Bldg. 30, Rm. 117. available for NIH employees beginning Proofreading Apr. 2 Mar. 19 The newly elected officers-Greg Koski, Thursday, Feb. 5, in Bldg. 31, Rm. 8A-05. Medical Terminology II Mar. 2 Feb. 13 commodore; Jeff Bluestone, vice commo­ Tax assistance (walk-in service) is sched­ Medical Terminology I Mar. 3 Feb. 13 dore and racing chairman; Warren Ferris, uled from 10 a.m. to 2 p.m. Tax assistance rear commodore; and Tom Fioretti, fleet (by appointment only) is from 8:30 to 10 To learn more about these and other captain-will outline the club's plans for a.m. and from 2 to 5 p.m. courses in office and communications skills, 1981. In addition, sailing films will be A telephone extension will be published contact the Training Assistance Branch, shown. For information, contact A. Skeel, in the next issue of The NIH Record and 496-2146. 496-1643. D posted on all official bulletin boards. D

Page 2 The NIH Record January 21, 1981 Dr. John Lynch Retires; Dr. J. Brody Most Decorated Member Initiated Model Employee Of the U.S. Public Health Service Health Program By Clarissa K. Wittenberg Dr. John Lynch, NIH occupational health officer, retired Jan. 1 after 30 years' service Dr. Jacob Brody, associate director for at NIH. He was medical director of the Em­ epidemiology, demography, and biometry ployee Health Service for 24 years, and later at the National Institute on Aging, was cited administratively responsible for the Occu­ recently as the most highly decorated pational Medical Service which replaced the member of the U.S. Public Health Service EHS. Commissioned Corps. After 2 years of active duty during the For extraordinary service during his PHS Korean War, Dr. Lynch was assigned to NIH career, Dr. Brody has received the Hazard­ as a commissioned officer, and in 1957 was ous Duty Award, with one gold star and among the first group of physicians Board four bronze stars; the Foreign Duty Award, Certified in Occupational Medicine. with one gold star and three bronze stars; the Isolated Hardship Award, with one gold star and four bronze stars; and the Special Assignment Award, with one gold star and four bronze stars. In 1980, Dr. Brody was also elected presi­ dent of the American Epidemiological Soci­ ety, and presented with the Kolker Award for service in geriatric medicine by the Dr. Brody joined the U.S. Public Health Service Lavindale Hebrew Geriatric Center in Balti­ in 1957. more. In the past, Dr. Brody was honored by From 1965 until 1974, Dr. Brody headed Guam for his contribution to the under­ the Epidemiology Branch of the National standing of amyotrophic lateral sclerosis Institute of Neurological and Communica­ and parkinsonism dementia. tive Disorders and Stroke. He left there for The National Multiple Sclerosis Society a year in 1974 to become research coor­ praised him for distinguished service on dinator for the Unified Program of the behalf of the "MS cause." He was also cited Atomic Bomb Casualty Commission in Dr. Lynch is a staunch supporter of the com­ by the American Medical Writers Associa­ Hiroshima, Japan. missioned corps. He is particularly pleased that tion for his contribution to Viral Infections Before joining NIA in 1977, he served as two of his daughters, Theresa Morrison (I) and of Humans, which was selected as Best Jeanne Odom, recently joined the corps as chief of the epidemiological and special nurse officers and are now working in the CC. Book on a Medical Subject for Physicians in studies branch of the National Institute on 1977. Alcohol Abuse and Alcoholism. A graduate of the State University of New Currently, Dr. Brody is vice chairman of He directed one of the first alcoholism York Downstate College of Medicine, Dr. the National Council on Alcoholism's Blue and mental health counseling programs for Brody completed his internship at Roosevelt Ribbon Commission on Alcoholism and government employees, and was responsi­ Hospital in New York. Aging. He also serves on four commissions ble for developing a model occupational During his first 2 years he served as an on continuing care for the elderly and other health program for NIH employees. Also, epidemic intelligence officer at the Center related health committees. he was the NIH representative on numerous for Disease Control in Atlanta. Sub­ He has published widely on the boards and advisory committees in the sequently, he became a staff member of the epidemiology of infectious diseases, slow Parklawn Bldg. National Institute of Allergy and Infectious viruses, neurologic diseases and other As he leaves, the constant growth of NIH Diseases and served as a medical officer in chronic illnesses; as well as on alcohol facilities stands out in Dr. Lynch's mind. the Middle American Research Unit in the abuse, alcoholism, and aging. "When I first came to NIH," he said, "the Panama Canal Zone. Among his current professional interests CC was under construction. Now that I am In 1962, Dr. Brody was one of the first is the complex issue of the epidemiology of retiring, the construction is still going on." American scientists invited to conduct re­ healthy, normal aging. Under Dr. Brody's He is quite interested in seeing how things search in the USSR, working at the Institute direction NIA is embarking on studies of the work out with the ACRF when it is com­ of Poliomyelitis and Virus Encephalitis in last days of life, the natural history of senile pleted. Moscow. He later served as chief of the dementia, and the process of aging as ex­ He is certain that he will be active during epidemiology section of the Arctic Health perienced by relatively well people living

his retirement, devoting time to amateur Center in Anchorage, Alaska. independently in three communities. □ radio, sailing, and camping. His 10 children are scattered throughout the country, and he and his wife Mary are looking forward to visiting them and their R&W Awardees Cited for Advancing Goals grandchildren. They will be spending their

winters in Boca Raton, Fla. □ In recognition of those persons who port, or inspiration has enriched R&W's "give generously and willingly of their time goals. and energy to advance the goals" of the Outstanding Service Award to Gerard Smithsonian Jazz Repertory Ensemble NIH Recreation & Welfare Association, a Stiller and Doren Vest, presented to com­ To Be Featured January 25 newly established R&W Awards Committee mittee chairmen for outstanding service to has approved the following presentations R&W. The fifth concert of the 1980-81 Chamber during 1980: Exceptional Service Award to Howard Music Series, sponsored by the Foundation Drew and Randy Schools, given to prime Presidential Award to Colleen Keegin, for Advanced Education in the Sciences, will movers on a specific project. given to an R&W member selected by the feature the Smithsonian Jazz Repertory En­ Executive Council Award to Cecile Pettit, R&W president. semble. Kathleen Demestihas, Agnes Richardson, The concert will be held on Sunday, Jan. Board of Directors Award to Jack Benson, and Martin Peller, given to those council 25, at 4 p.m., in the Masur Auditorium. given to a person not an R&W member, members chosen by the entire council for Admission is by ticket only. □ whose unique contribution in service, sup- exceptional service. January 21, 1981 The NIH Record Page 3 Researcher's Mice Colonies To Star in Segment Of Japanese Educational Film

By Marilyn Sargent, ADAMHA News Dr. John 8. Calhoun's famous mice, known for their participation in his studies on overpopulation, will star in a segment of a Japanese-produced educational film. Tentatively entitled "Human Beings," the six-part film will examine life in terms of birth, DNA, the brain, civilization, science, and religion. The producer, Cine-Science Company, Inc. of Tokyo, designed the series for high school students and plans to make it avail­ able in a number of languages, including English. What does a film about humans have to do with Dr. Calhoun's mice? According to Dr. Calhoun, chief of the National Institute of Mental Health's Unit for Research on Be­ havioral Systems, the behavior of mice, when subjected to the stress of over­ crowding, has implications for the human race. Overcrowding leads to increased interac­ tions among the population, interrupting normal routines and sapping energies otherwise devoted to essential life tasks, says Dr. Calhoun. Dr. Calhoun (second from I) watches the mouse habitat with the Japanese film crew. When overcrowding affects a species, its highest forms of behavioral achievement times, those hours that might be compara­ optimum number for the habitats. Each uni­ begin to unravel. Among mice, territorial, ble to daylight in the real world, when they verse was allowed to increase to three times mating, and maternal behaviors fall apart, would be vulnerable to predators. the optimum !)Umber in the second gener­ leading to the eventual dissolution of the When not eating or drinking, many lie in ation. population. huddled, apathetic masses, evincing no In one universe, the scientists taught the Crowding Diminishes Ability interest in the opposite sex. Having been residents collaborative skills as survival conditioned to overcrowding, they con­ techniques. For example, the rats were For humans, says Dr. Calhoun, the high­ tinue to eat, drink, and sleep in squirming, est attainment is not procreation, but the taught to seek water in pairs. Only through congested groups, ignoring unused feed­ cooperative action with a fellow rat can creation and reproduction of ideas. Severe ers, water spouts, and empty spaces nearby. overcrowding among humans, which has water be obtained. In contrast to the earlier experiment, the Rats Taught Cooperation not occurred worldwide as yet, may di­ improved environmental conditions have minish people's ability to respond creatively enabled the seventh generation females to After teaching cooperative drinking, the to their environment, he speculates. continue to become pregnant. scientists have helped the rats to add coop­ Dr. Calhoun has been studying the im­ Nevertheless, none has been able to rear eration among "clans" to their behavioral pact of overcrowding on mice for more than its young to adulthood. As in the past ex­ repertoire. 20 years. In an early and famous experi­ periments, the population is threatened The researchers have identified two major ment, a freely reproducing mouse popula­ with extinction. resident types: the high-velocity rats, those tion reached eight times the optimum den­ In addition to studying mice, Drs. Cal­ more socially interactive and aggressive, sity, leading to its eventual extinction. houn and Hill are working with two rat uni­ and the low-velocity inhabitants, who tend Population decline set in after the last verses, each started with 16 residents, an to be more socially withdrawn. generation proved incapable of effective mating. This result led the researcher to Food is being made available to both begin a new set of studies, now in the fifth high- and low-velocity animals, but not and last year. when members of both groups are present At present, Drs. Calhoun and James Hill, at the same time in the food compartments. a visiting scientist, are observing the Thus, if they are to feed, the rats must seventh and last generation of mice to live (See MICE, Page 8) in a specially built "mouse universe," per­ fectly designed for an optimum density of 200 residents. Money-Saving Main Dishes Free of natural predators and inclement Available From USDA weather, the mouse population increased to four times the optimum density for adult Been wrestling with your food budget mice. Once again, despite much effort by lately? One way to keep your taste buds the investigators to improve the quality of content with lower cost foods is to whip up the animals' physical and social environ­ creative money-saving main dishes. ment, overcrowding has produced aberrant To give you some ideas on this approach, mouse behaviors. the U.S. Department of Agriculture has a With the exception of a few dominant booklet offering tips on cutting food costs males, feeding and mating behaviors have and recipes to help you. For a copy of become abnormal. Ordinarily mice are Mice conditioned to overcrowding continue to Money-Saving Main Dishes, send 60 cents to nocturnal beings, but in overcrowded con­ huddle in their habitat, ignoring unused feed­ the Consumer Information Center, Dept. ers, water spouts, and a nearby open area. ditions, subordinate mice feed during "off" 126H, Pueblo, Colo. 81009. □ Page 4 The NIH Record January 21, 1981 • Americans Health 'Never Better,' Dr. Jesse Roth Honored Says Vear-End Annual Report For His Diabetes Research

The United States has scored notable likely than whites to die from this cause. achievements in health promotion and dis­ The report also shows that mortality from ease prevention, but the potential for im­ respiratory cancer has been increasing fas­ provement is still great. ter for women than for men. It was five A report, Health, United States, 1980, re­ times higher for men than women in 1970; cently issued by HHS, examines selected in 1977, the ratio was down to 3.7. issues of current concern and provides de­ An examination of the recent rise in the tailed statistics on the Nation's health cesarean deliveries in this country indicates status. A prevention profile prepared for that fundamental changes in obstetrical this year's edition provides baseline data for practice has occurred. In 1978, 15 percent, tracking progress in disease prevention and or more than 500,000 births were delivered health promotion. by cesarean, compared with 5 percent in The 1970's saw a rise in life expectancy to 1970. a record 73.3 years, an increase of 2.7 years The report shows a marked trend toward since 1970. The death rate from heart dis­ equity of access to medical care regardless ease, the Nation's No. 1 killer, dropped by of income. The percent of population see­ nearly 20 percent, and death from stroke by ing a physician within 2 years has increased 33 percent in the years 1970 to 1978. in every age and color group, with the Although cancer is still the second lead­ greatest increases for the poor. The author or co-author of over 150 publica­ ing cause of death, and the overall mortality However, there is no definitive evidence tions, Dr. Roth has received numerous honors rate from cancer has increased by 6 percent that the poor's level of use is commensurate and awards for his research in diabetes. since 1950, the death rate for those patients with their needs for medical care, the re­ under 45 has decreased and is declining for port says. In addition, the poor receive Dr. Jesse Roth, chief of NIAMDD's Dia­ those between 45 and 49. fewer preventive services and less dental betes Branch, was recently presented the A. These decreases are attributed to lower care than the nonpoor. Cressy Morrison Award in Natural Sciences death rates from breast cancer in younger In a comparison of hospital utilization in at the New York Academy of Sciences' 163rd women, decreases in ILJng cancer in the U.S. with that of nine other countries, Annual Meeting in New York City. younger men, and in substantial improve­ the report shows that this country has one The honor included a certificate of cita­ ments in treatment of childhood leukemia of the highest rates of hospitalization but tion and $1,500 in recognition of Dr. Roth's and Hodgkin's disease. one of the shortest mean lengths of stay. significant accomplishments in the field of Accidents remain the fourth leading cause For people 65 and over, hospital stay in the diabetes resea reh. of death in the U.S. However, in 1978, acci­ U.S. was more than 5 days shorter than in Dr. Roth has pioneered studies that dem­ dents accounted for 20 percent of all years seven other countries studied. onstrate the importance of receptors for of life lost. For young people under age 35, Medical care expenditures continue to insulin in determining the sensitivity and accidents are the chief killer. rise rapidly, topping $212 billion in 1979. responsiveness of target cells to circulating The high level of teenage childbearing This was an increase of more than 12 per­ insulin. continues. Numerous health risks are as­ cent over the previous year. Price increases These findings have shown that various sociated with early childbearing. alone accounted for more than two-thirds clinical diabetic states relate not only to the Although birth rates are not as high for of the increase in 1979. production and circulating levels of insulin, these young women as they were in the The report shows that a very large share but also to the ability of the target eel Is to early 1970's, the U.S. has one of the highest of national health expenditures go for con­ respond to the available insulin. D rates of teenage fertility among indus­ ditions that are to some degree prevent­ trialized nations. able. For example, heart disease, cancer, The report shows that the sustained de­ stroke, violence, and respiratory conditions Lamport Award Presented clines in recent years for infant mortality in accounted for 46 percent of the total costs the U.S. between 1960 and 1977 is due of illness in 1975. To Dr. Kenneth R. Spring largely to improved survival of low birth "It is clear that our prevention initiatives Dr. Kenneth R. Spring, staff physiologist weight babies. are bearing fruit," said Surgeon General Dr. in NHLBl's Kidney and Electrolyte Stroke mortality declined by one-third Julius B. Richmond, HHS Assistant Secretary Metabolism Laboratory, was recently pre­ between 1970 and 1977. The decrease was for Health. D sented the Dr. Harold Lamport Award for especially large for blacks, who are more Young Investigators in Physiology or Biophysics. 'How To Apply for a Job' DNA Symposium Tape Cassette The New York Academy of Sciences, Audit Package Now Available Is Now Available which bestows the award annually, cited Dr. Spring for his "excellence in research and NIH employees are invited to use the in­ "DNA, the Cell Nucleus, and Genetic teaching of physiology." dividual learning program, "How to Apply Disease," the cassette recording of the pro­ In 1975 Dr. Spring came to his present for a Job," an instructional package that is ceedings of the recent symposium, is now post, where he has been studying the designed to help Federal employees when available in the NIH Library's audiovisual body's fluid balance, attempting to deter­ they apply for another Government job. collection. mine the pathways taken by salt and water Application Advice Offered The symposium, sponsored by the Na­ across epithelial tissues. tional Institute of Arthritis, Metabolism, and In addition to his laboratory work, Dr. It consists of a 25-minute audiocassette Digestive Diseases in October, featured Spring is an assistant professorial lecturer in tape and a workbook. The topics covered presentations by eight genetics experts. physiology at the George Washington Uni­ are: hints about vacancy announcements; a A program of speakers and topics is avail­ versity School of Medicine. brief explanation of the application proc­ able from the NIAMDD, (301) 496-3583. D He received his D.M.D. degree from Tufts ess; how to fill out an SF 171, Personal University School of Dental Medicine, and Qualifications Statement; and advice on his doctorate in physiology from the State interviewing. any personnel or EEO office. University of New York at Buffalo. Dr. A complete package of materials is avail­ A written version of the audiotape is Spring is the recipient of numerous honors able at the Individual Learning Center, Bldg. available in the Learning Center for deaf and awards including the Alpha Omega 31, Rm. B2C-25, or it may be borrowed from and hearing-impaired employees. D Student of the Year Award in 1963. D

January 21, 1981 The NIH Record Page 5 Beginners' Judo Class To Start FIC Research Fellows Visiting Scientist The NIH Judo Club will still accept appli­ Over the last 3 months, three foreign re­ cations for the winter beginners' class. This searchers have come to NIH to continue Program series of 12 classes in basic judo will be held their work under the Fogarty International Participants on Tuesdays from 6 to 7:30 p.m. beginning Center's International Research Fellowship Jan. 27 and ending Apr. 14. Classes will be program. Sponsored by Fogarty lnternat'I Center held in the old gymnasium of Stone Ridge Dr. Adeline Albert, a senior assistant in School, Cedar Lane and Wisconsin Ave. medical statistics at the University of Liege, 12/29-Dr. Rudolf Billeter, Switzerland, Lab­ oratory of Neurochemistry. Sponsor: Dr. Dr. Thomas E. Malone, NIH Deputy Di­ Belgium, arrived in October to work with Seymour Kaufman, NIMH, Bg. 36, Rm. 3D30. rector, will serve as chief Kodakan judo in­ Dr. Eugene K. Harris in the Division of 12/29-Dr. Hiroetsu Nakashita, Japan, Labora­ structor, or Sensei, for the club. Dianne Computer Research and Technology. tory of Molecular Biology. Sponsor: Dr. Ernst Moore, holder of the first degree black belt Also coming to study is Dr. Guo Wei Lu, Freese, NINCDS, Bg. 10, Rm. 3D02. (Shodan), will be the coinstructor. assistant professor in neurophysiology at 12/29-Dr. Alicja Pauler, USA, Dept. of Re­ The fee is $35. Application forms can be Peking Second Medical College, Beijing, habilitative Medicine. Sponsor: Dr. Lynn obtained from the R&W Activities Office, China, who arrived in December to work at Gerber, CC, Bg. 10, Rm. 5D37. Bldg. 31, Rm 1A-18, Susan Stewart, Bldg. 31, the National Institute of Dental Research 12/29-Dr. Mika Scheinin, Finland, Clinical Rm. 4C-02, 496-5586; or Dr. Malone, Bldg. with Dr. Ronald Dubner. Psychobiology Branch. Sponsor: Dr. Frederick K. Goodwin, NIMH, Bg. 10, Rm. 45239. 1, Rm. 132. Space is limited so interested January saw the arrival of Dr. Rene Riz­ 1/1-Dr. Greece, Pediat­ zoli, a cellular biochemist at the University Maria K. Antoniadou, persons should return the completed form ric Oncology Branch. Sponsor: Dr. Arthur S. to either Ms. Stewart or Dr. Malone im­ Hospital of Geneva, Switzerland. He will be Levine, NCI, Bg. 10, Rm. 3B12. mediately to assure a place in the class. working under the preceptorship of Dr. G. 1/1-Dr. Harishchandra Chopade, India, En­ D. Aurbach at the National Institute of Ar­ vironmental Biology Branch. Sponsor: Dr. H. B. thritis, Metabolism, and Digestive Dis­ Matthews, NIEHS, Research Triangle Park, N.C. eases. □ 1/1-Dr. Peter Robinson, United Kingdom, Laboratory of Neurosciences. Sponsor: Dr.

Stanley Rapoport, NIA, GRC, Baltimore. 1/1-Dr. Surinder Safaya, India, Laboratory of Pathophysiology. Sponsor: Dr. Pradman K. Qasba, NCI, Bg. 10, Rm. 81842. 1/1-Dr. Tomosada Sugimoto, Japan, Neurobiology and Anesthesiology Branch. Sponsor: Dr. Stephen Gobel, NIDR, Bg. 30, Rm. 810. 1/2-Dr. Alfonso Garria-Vela, Mexico, Endoc­ rinology and Reproduction Research. Branch. Sponsor: Dr. Maria L. Dufau, NICHD, Bg. 10, Rm. 12N216.

1/2-Dr. Harold H. Allen, USA, Arthritis and Rheumatism Branch. Sponsor: Dr. John Decker, NIAMDD, Bg. 10, Rm. 9N222.

1/2-Dr. Miklos Palkovits, Hungary, Laboratory of Clinical Science. Sponsor: Dr. Irwin J. Kopin, NIMH, Bg. 10, Rm. 2D46.

1/5-Dr. Andrew Simpson, United Kingdom, Laboratory of Parasitic Diseases. Sponsor: Dr. F. Mark Dantzler cuts a piece of cake for Dr. Alan Sher, NIAID, Bg. 5, Rm. 116. Malone, host of the party honoring Mr. Members of the Chinese Study Mission on 1/5-Dr. Marc Vigny, France, Laboratory of De­ Dantzler as the first NIH Judo Club member to Health Statistics visited with Dr. Robert Gor­ velopmental Biology and Anomalies. Sponsor: be awarded a first-degree black belt shodan by don, special assistant to the Director of NIH, Dr. George R. Martin, NIDR, Bg. 30, Rm. 416. and with other key administrators on their re­ the U.S.. Judo Federation. Mr. Dantzler has been 1/7-Dr. Jose G. Castano, Spain, Laboratory of a judo student of Dr. Malone's since he was in cent visit. The delegation's purpose was to learn Molecular Biology. Sponsor: Dr. Michael Cot­ the fifth grade, and is currently pursuing a more about collection, analysis, and the use of tesman, NCI, Bg. 37, Rm. 2E22.

career in physical education at the University of statistical health data in solving health problems 1/7-Dr. Amelia Nieto, Spain, Endocrinology Maryland. in China. and Reproduction Research Branch. Sponsor: Dr. Kevin J. Catt, NICHD, Bg. 10, Rm. 12N202. The Search for Ochotona­ Enjoy Singing Choral Music? Tibet' s Elusive Animal Parking Permits Go on Sale Rehearsals Begin Jan. 25 Will Be Lecture Topic On 21st of Each Month All persons who would like to be mem­ A 2-week field trip to Tibet in search of Beginning on the 21st of each month, or bers of a choral group and sing sacred and the Ochotona, an elusive mouse-hare and the first working day thereafter, parking secular music are invited to join the NIH the suspected Asian plague carrying animal, permits go on sale for the coming month. Singers. will be described by Dr. Richard Mitchell in These permits may be purchased at: The Singers, an R&W-sponsored activity, the Masur Auditorium on Thursday, Jan. 29, Parking Office Monday through Friday, will be preparing a two-part spring concert at 1 p.m. Bldg. 31, Rm. B1C-15 8:30 a.m. to 3 p.m. featuring well-known choruses from Gilbert Dr. Mitchell is a zoologist at the Office of Bldg. 38-A Last Friday of each month, and Sullivan operettas, as well as sacred Endangered Species, U.S. Department of Main Lobby 9 a.m. to noon

music by Haydn, Franck, and Gluck. Interior. Bldg. 10 First and Last Monday and Tuesday He was part of a delegation of interna­ Masur Aud. lobby of each month, 10 a.m. to 2 p.m. Rehearsals Every Other Week tional scientists which was given unlimited Rehearsals are held every other week in Blair Bldg. Last Thursday of each month, access to travel in Tibet by the Government Conf. Rm. 110 9:30 a.m. to noon homes of members. The first rehearsals will of China for the first time. be on Sunday evenings, Jan. 25, Feb. 8, and The slide lecture is entitled: From Beijing Federal Bldg. 3rd Wednesday of each month, Conf. Rm. B1-19 11 a.m. to noon Feb. 22. There are no auditions, but sight­ Across the Tibetan Plateau in Pursuit of the reading ability is required. Tenors are par­ Elusive Ochotona. This event is sponsored Landow Bldg. 3rd Wednesday of each month, ticularly needed. by the NIH Asian-American Cultural Com­ Conf. Rm. C 9:30 to 10:30 a.m. For further information, call Dr. Lewis M. mittee, and for further information call G. Westwood Bldg. Last Wednesday of each month, Norton, 496-6037. Schiffmann, 496-1156. Conf. Rm. D 9:30 a.m. to 1 p.m. □ □ Page 6 The NIH Record January 21, 1981 Type Ill Hyperlipidemia Is Topic NINCDS Director Dr. Tower To Retire on Feb. 1; Of Combined Clinical Conference His Distinguished Fed'I Career Spans 40 Years A Combined Clinical Staff Conference on Type Ill Hyperlipidemia will be held in the Dr. Donald B. Tower, who has guided Masur Auditorium on Friday, Jan. 23, at 3:30 Federal research in the neurosciences for p.m. nearly 8 years as Di rector of the National The discussion will be moderated by Dr. Institute of Neurological and Communica­ H. Bryan Brewer, Jr., chief of the Molecular tive Disorders and Stroke, will retire on Disease Branch, National Heart, Lung, and Feb. 1, ending a Federal career that spans Blood Institute. more than 40 years. 3 Speakers Announced An internationally known neurochemist and neurologist, Dr. Tower has spent the The program includes three other speak­ last 28 years with NINCDS, first as chief of ers from the Molecular Disease Branch. the Clinical Neurochemistry Section and Dr. Loren Zech, a senior investigator, will later as chief of the Laboratory of speak on Diagnosis and Clinical Features of Neurochemistry, as well as acting associate Patients With Type Ill Hyperlipo­ director for extramural programs. He be­ proteinemia. came Institute Director in 1974. Dr. David Schwartz, Hospital of the Uni­ In retirement, Dr. Tower's first under­ versity of Pennsylvania, will cover the taking will be a biography of Johan Thomas Pathological Features of Type 111 Hyper­ Hensing, the German physician who dis­ lipoproteinemia. Apolipoprotein E covered phosphorous in the brain and who Metabolism in Type Ill Hyperlipo­ in 1719 wrote the first monograph on brain proteinemia Patients will be discussed by chemistry. clinical associate Dr. Dick Gregg. The Hensing biography will extend Dr. Treatment of Type Ill Hyperlipo­ Tower's already long list of publications. He proteinemia will be addressed by Dr. Ernst is the author of more than 130 scientific pa­ Schaefer, a senior investigator in the pers and monographs, most of them deal­ A commissioned officer in the PHS, Dr. Tower Molecular Disease Branch. ing with neurochemistry. holds the rank of Assistant Surgeon General­ This conference is scheduled for publica­ His research interests have ranged from the equivalent of major general. tion in the □ Annals of Internal Medicine. studies on epileptic seizure mechanisms with emphasis on transmitter and ionic ab­ Neurochemistry, neurochem istry editor of CC Employees Honored normalities, to problems of the ischemic Experimental Brain Research, and has served At Awards Ceremony neuron and the role of astroglial cells in on the editorial board of several other jour­ brain edema. nals. More than 300 Clinical Center employees While NINCDS Director, Dr. Tower has In 1969, he headed the Neurochemistry were honored for outstanding work during overseen an extensive survey of neurologi­ Exchange Mission to the Soviet Union the past year at the Ninth Annual Awards cal and communicative disorders research. under the U.S.-Soviet Exchange Program. Ceremony held recently in the Masur The resulting three-volume publication, Ten years later, he was a member of the Auditorium. The Nervous System, appeared in 1975 to WHO delegation to the People's Republic Seven Public Health Service Commenda­ commemorate the lnstitute's 25th anniver­ of China. tion Medals were awarded to: Dr. Ronald sary. In 1974 Dr. Tower was awarded the HEW Elin, chief, Clinical Pathology; Dr. Lynn H. Dr. Tower also reorganized the Institute Meritorious Service Medal and in 1977, the Gerber, chief, Rehabilitation; Andrea Myer, along program lines to provide added em­ PHS Distinguished Service Medal as well as Medical Records; Alberta Bourne and Elaine phasis for extramural program manage­ numerous other honors. Offut, Nutrition; Dr. Harvey Klein, Blood ment. Dr. Tower is a graduate of Harvard Col­ Bank; and Dr. Thomas Shawker, Diagnostic In addition, under his direction, seven lege. He received his M.D. degree from Radiology. panels of experts developed a comprehen­ Harvard Medical School in 1944, and his CC Director Dr. Mortimer Lipsett pre­ sive long-range plan for research in Ph.D. from McGill University in 1951. While sented the NIH Award of Merit to Mary n.eurological and communicative disorders. at McGill, he was chosen a Markle Scholar Thompson, acting chief of the Nursing De­ The National Research Strategy, completed in Academic Medicine. partment, for "consistent astute leadership in 1978, identifies achievable goals and He served on active duty in the Naval in promoting and achieving Nursing De­ areas deserving increased research interest Reserves late in World War 11, and as a partment and Clinical Center objectives." and support. lieutenant (junior grade) in the Navy Medi­ Two EEO awards were presented-to El­ "I grew up with the modern development cal Corps. si lee Des Bordes, LPN, Heart and Lung of neurochemistry," said Dr. Tower. He has Before coming to NINCDS, Dr. Tower was Nursing Service, for her work as EEO contributed much to that development. an assistant professor of experimental counselor and chairperson of the CC EEO He is a cofounder and first treasurer of neurology at McGill, and an associate advisory committee, and to Dr. Jay Shapiro, the American Society of Neurochemistry, neurochemist at the Montreal Neurological CC associate director, for his efforts to re­ organized in 1968; an adviser to the World Institute. cruit minority applicants for the Clinical and Health Organization for the Collaborating In October 1980, he returned to the Research Associate Programs. Centers Program of research and training in Montreal Neurological Institute to deliver In addition to quality increase, cash, and the neurosciences; and a member of the the 46th annual John Hughlings Jackson length-of-service awards, Samuel Chapman, WHO Expert Advisory Panel on Neurosci­ memorial lecture on the prospects and acting chief, Fabric Care Department, was ences. challenges for neurology and the neurosci­ cited for "outstanding leadership." □ He has been chief editor of the Journal of ences. □

Task Force Report Identifies Respiratory Disease Problems research, and to recommend the types of studies needed for a well-focused, manage­ A new publication, Task Force Report on consultants represent various aspects of able epidemiology program. Epidemiology of Respiratory Diseases, is pulmonary medicine as well as epidemiol­ Single, free copies of the publication may now available from the National Heart, ogy and biostatistics. The group is con­ be obtained from the Division of Lung Dis­ Lung, and Blood Institute. cerned with identifying problems that can eases, NHLBI, Westwood Bldg., Rm. 6A-16, The 13-member task force and its four only be resolved through epidemiologic Bethesda, Md. 20205. □

January 21, 1981 The NIH Record Page 7 NIH CFC Contributions as of December 31 MICE (Continued from Page 4) NIDR 11,104 (Goal 8,076) learn "clan" membership and to act in con­ NLM 17,120 (Goal 13,383) cert with others like themselves. NIA 3,438 (Goal 2,688) Through these experiments, the re­ searchers are attempting to help the rats NIAMDD 16,727 (Goal 13,943) build communication networks and social DRS 7,822 (Goal 6,812) structures that will improve their coping ca­ pabilities and reduce the pathologies NIGMS 5,424 (Goal 4,975) brought about by population density in DCRT 7,118 (Goal 6,562) doing so. NCI 41,885 (Goal 39,325) Dr. Calhoun would experimentally verify his theory that humans' ability to expand on NHLBI 18,687 (Goal 18,013) past knowledge and to collaborate in the DRG 13,611 (Goal 13,375) development of new coping and information-processing strategies has given NIAID 15,474 (Goal 15,583) them the ability to survive dramatic popula­ NEI 3,295 (Goal 3,356) tion increases. "Analysis of the growth of world popula­ DRR 2,685 (Goal 2,824) tion over the past 2,000 years indicates that NINCDS 12,840 (Goal 13,834) each successive doubling of population re­ quired only half the time of the prior NICHD 8,944 (Goal 10,047) doubling," reports Dr. Calhoun. OD 32,943 (Goal 40,554) "Beginning sometime about 43,000 years 17,567 (Goal 22,351) ago, the population began to increase. The cc first doubling took 20,000 years, the second FIC 1,751 (Goal 2,299) took 10,000 years, the next 5,000 and so on, NIH 238,435 (Goal 238,000) until now we are in a period where 40 years encompasses a doubling of world popula­ 0 10 20 30 40 50 60 70 tion. Thus, we have the present crisis and talk of population explosion." Percent But he remains optimistic for two rea­ The NIH Combined Federal Campaign exceeded its dollar goal this year for the first time since the sons. First, statistics gathered through the 1975 campaign. The bar graph shows the amount of donations collected from each 8/1/D. The total United Nations indicate that the worldwide of $238,435 is the largest amount ever collected here. "All of NIH is to be congratulated for making rate of population growth began to de­ this year's. campaign the most successful ever at NIH," said DRS Director Dr. Joe R. Held, vice chairman of the NIH campaign. crease in 1975. The world population will continue to rise until it reaches a peak of more than 9 billion at about 2065. Then the decreased rate of Dr. William Gay Will Serve as Director growth will begin to have an impact and the population will start to decline at half the Of DRR's Animal Resources Program rate at which it previously increased, Dr. Calhoun theorizes. tion, which upgrades institutional animal The other good news, according to Dr. resources, supports facilities engaged in the Calhoun, has to do with humans' ability to diagnosis and control of animal disease, de­ process information and create solutions velops highly trained specialists in labora­ for the problems of living, the evolution of tory animal medicine and science, and sup­ the "social brain." ports development of specific colonies of Although the human race's capability for laboratory animal models. inventing answers and processing informa­ Dr. Gay received his DVM from Cornell tion has not quite kept up with its popula­ University, and is a graduate of the Federal tion growth (according to Dr. Calhoun, Executive Institute. He has been associated idea processing doubled once for every two with NIH since 1954. doublings of the population), the future is Prior to coming here, he practiced veteri­ promising. With the help of computers, the nary medicine at Richmond Hill, N.Y. In information-processing capability will con­ 1952, he was commissioned a lieutenant in tinue to expand beyond the turnaround in the veterinary corps of the U.S. Army and the population growth. spent 2 years in charge of the laboratory Eventually, says Dr. Calhoun, progress in animal colony at the Walter Reed Army In­ information processing will begin to de­ stitute of Research in Washington, D.C. cline, but at a rate slower than that of the Joining the Division of Research Services population decline. So for some period of as chief of the Animal Hospital Section in The winner of the 1971 AALAS Griffin award, Dr. time, if the human race has not "de­ 1954, Dr. Gay later served concurrently as Gay is the author of over 20 papers in the field structed" beforehand, creativity will sur­ assistant chief of the central animal colony. of laboratory animal science and has served on pass population growth. D numerous NIH committees. In 1963, he became a senior program offi­ cial in the Animal Resources Branch of the Dr. William I. Gay, former director of the Division of Research Facilities and Re­ He was acting associate director of Extramural Activities Program of the Na­ sources. NIGMS during most of 1970, and the fol­ tional Institute of Allergy and Infectious In 1966, Dr. Gay joined the National In­ lowing year joined NIAID. Diseases, has been named director of the stitute of General Medical Sciences as pro­ Dr. Gay has served as president of the Division of Research Resources' Animal gram director for comparative medicine and D.C. branch of the American Veterinary Resources Program. also program administrator for the radiol­ Medical Association, and the American As­ The program administers activities of ogy and physiology training programs. He sociation for Laboratory Animal Science. NIH's Regional Primate Research Centers became chief of the Research Grants Branch He has also been active in a number of and the Laboratory Animal Sciences opera- in 1967. committees. D

Page 8 The NIH Record January 21, 1981 Three New Members Named Ultrasonic System Visualizes Tongue Motions, To NLM's Board of Regents Useful in Diagnosis of Lingual Functions Three new members were named to the National Library of Medicine's Board of Measuring oral-motor dysfunction in �egents. persons with amyotrophic lateral sclerosis They were Drs. Gwendolyn S. Cruzat, and other neurological diseases that affect William D. Mayer, and Charles E. Molnar. talking, chewing, and swallowing may now The first meeting to be attended by the be aided by an ultrasonic system that vis­ three new regents was held on Oct. 9-10, ualizes dynamic motions of the tongue and was presided over by the newly-elected during speech. chairman of the board, Dr. Nicholas E. Devised by NIH researchers-Barbara Davies. Sonies, Rehabilitation Department, Dr. Dr. Cruzat is professor of library science CC; Thomas Shawker, Diagnostic Radiology De­ at the University of Michigan's School of Li­ partment, and Thomas E. Hall, BEIB, brary Science. In 1978, she spent 4 months CC; DRS-the system provides a reliable and at NLM under provisions of the Inter­ noninvasive technique for assessing lingual governmental Personnel Act. functions. During this time she studied ways to con­ nect library school education and research Patient Speaks Normally activities more closely with key problems in In the past, researchers had to impose health-science librarianship. awkward procedures that interfered with Ultrasound image of normal tongue motion Dr. Mayer, a pathologist, is president of normal articulation. The new system allows during production of the phoneme /a/. Upper the Eastern Virginia Medical Authority. the patient to speak normally without jaw surface of tongue corresponds to white curved He served as Dean of the Missouri­ restrictions or exaggerated head postures. band extending across the middle of sector. Columbia School of Medicine, and directed It also allows comparison and retrieval of useful in diagnosing a variety of neurologi­ the University's Health Services Research multiple repetitions of speech samples in a Center Program. Prior to becoming univer­ cal conditions such as disorders associated digital format that can be subjected to com­ with cerebellar degeneration that affect the sity president, Dr. Mayer was assistant chief puter analysis. medical director for Academic Affairs, Vet­ muscles and nerves controlling the tongue, erans Administration. The system includes such devices as a palate, lips, pharynx and larynx. The third new regent, Dr. Molnar, cur­ specially equipped wheelchair, the ul­ One application involv�s predicting rently holds a number of positions at trasonic imaging system with an adapted oral-motor problems that are life­ Washington University (St. Louis, Mo.). He scanner, and a closed-circuit television threatening to the elderly and are some­ directs the university's computer Systems system that allows simultaneous monitoring times manifested as sleep and swallowing Laboratory and is a professor in the depart­ of speech and ultrasonic signals. disorders. If these problems are associated ments of computer science, electrical en­ An ultrasonic scanning system that vis­ with changes in the tongue itself, treatment gineering, and physiology and biophysics. ualizes dynamic motions during speech is may be devised. Dr. Molnar has previously served as a consultant for the National Cancer Institute, and has chaired the NIH's Computer and Biomathematical Sciences Study Section. His major research interests include infor­ mation processing in the nervous system, and the design and development of com­ puters for biomedical research. □ Pamphlet Tells How To Blow Your Whistle The Office of the Special Counsel of the U.S. Merit Systems Protection Board has issued a new pamphlet on the role of the special counsel and how whistle-blower complaints may be filed with the Office. The 14-page booklet, For Merit and Hon­ esty in Government, details the prohibited personnel practices under the Civil Service Reform Act of 1978. The whistle-blower pro­ visions and the special counsel's role in in­ vestigating allegations of prohibited per­ sonnel practices and violations of civil service laws, rules, and regulations are in­ cluded. Or. Shawker holds the transducer under the patient's chin while Ms. Sonies observes the patient's The pamphlet tells where and how to file ability to swallow. Ed Hall (I) makes certain that the image on the video screen is clear. complaints, including a list of the Office of Special Counsel's central and field offices. Monograph on Long-Term Care Reprinted by FIC The special counsel is charged with in­ vestigating allegations of certain statutorily A monograph, Long-Term Care in Six those offered in the U.S. For the new prohibited personnel practices and prose­ Countries: Implications for the United printing, the authors have briefly updated cuting offenders before the Merit Systems States, has been reprinted by the Fogarty recent developments and publications in Protection Board. International Center. the field. Copies of the pamphlet are available free In this 197-page monograph, Robert and Single copies may be obtained from the of charge from the Public Information Of­ Rosalie Kane compare services provided to FIC Publications Office, Bldg. 16A, Rm. 205, fice, Office of the Special Counsel, 1717 H the elderly in England, Israel, the Nether­ 496-4331. St., N.W., Washington, D.C. 20419. lands, Norway, Scotland, and Sweden to □ □ January 21, 1981 The NIH Record Page 9 Dr. John L. Ziegler Named Raymond W. Klecker, NCI Stride Student, Receives Editor-in-Chief of 'JNCI' Analytical Chemistry Award

Dr. John L. Ziegler has been named Raymond W. Klecker, a National Cancer editor-in-chief of /NCI, the Journal of the Institute Stride student attending American National Cancer Institute. He succeeds Dr. University, recently received the American John C. Bailar 111, who retired to teach at Chemical Society Analytical Chemistry Di­ Harvard University and to serve with the En­ vision Undergraduate Award. vironmental Pro­ The award is given annually to students tection Agency. with special interests or achievements in Dr. Ziegler has the field of analytical chemistry, and is been with NCI based on faculty recommendations. since 1966, most Mr. Klecker, who works in NCl's Clinical recently as deputy Pharmacology Branch, is among 426 under­ clinical director graduate students in the United States and and as associate Canada to receive the award this year. director for clinical The award consists of a certificate, a 15- oncology, Division month subscription to the journal, Analyt­ of Cancer Treat­ ical Chemistry, and an honorary member­ ment. ship in the American Chemical Society Di­ From 1967 to Dr. Ziegler vision of Analytical Chemistry until Dec. 31, 1972 he directed 1981. the Lymphoma Treatment Center in Kam­ Mr. Klecker has worked in the Clinical pala, Uganda, where he specialized in the Pharmacology Branch since February 1979. Mr. Klecker finishes his Stride training program treatment of Burkitt's lymphoma and other He helps design tests for measuring drug this spring and hopes to continue to do diseases endemic to Africa. levels in patient blood samples. graduate work in pharmacology. He received his M.D. degree from Cor­ nell University Medical College and a B.A. in English from Amherst College. In 1969, he received the PHS Commendation Medal; 1981 Directory of Health Groups in Washington Issued in 1972, the Albert and Mary Lasker Award. Other staff changes at /NCI include the The National Health Council has released metropolitan area. appointment of Edwin A. Haugh as manag­ the 1981 edition of its publication, entitled The national organizations listed include ing editor and Pamela T. Allen as assistant Health Groups in Washington: A Directory. voluntary health agencies, professional and managing editor. This sixth edition of the directory has membership associations, health-related Mr. Haugh holds a B.A. in English and been significantly enlarged over previous organizations, and accreditation/ history from the University of Delaware. On editions and now includes 252 national certification groups. the editorial staff since 1976, he replaces health organizations which are either head­ Phyllis Jay, who is now with the National quartered in Washington, D.C., or have an In Pocket-size Format Institute of Allergy and Infectious Diseases. office or representative in the Washington The 44-page directory-printed in a Mrs. Allen, a graduate of the University of handy, 4x9 inch, pocket-size format-is Maryland with a B.A. in English, has been a available for $4 a copy, prepaid, from the /NCI editor since 1977. Molecular Pharmacology, Division of National Health Council at 70 West 40th Dr. Ziegler appointed two new associate Cancer Treatment, NCI, and Dr. Richard M. Street, New York, N.Y. 10018. Discounts are editors to the /NCI board of editors: Dr. Simon, chief of the Biometric Research available when ordering five or more copies. Kurt W. Kohn, chief of the Laboratory of Branch, also in DCT. □ □

/. ! ----=--=-.---,)d l 1)vra d v@ _) About 75 National Institute of Dental Research employees recently attended a noontime career development seminar, sponsored by the Women's Concerns Subcommittee of the NIDR EEO Ad­ visory Committee. DPM Career Development Branch and NIDR panelists described training and career opportunities at NIH. Later, employees examined informational materials and discussed in­ dividual questions with the panelists: Dr. Ursula Lohmann, Margie Dyke, Pat Brady, Richard Jackson, Harry Marshall, and Gloria Cantu.

Page 10 The NIH Record January 21, 1981 BUDGET President's 1981 request by $126 million. Dr. Tully Is Honored The rescission proposal stated that (Continued from Page 1) budget restraints and competing demands by U. of Bordeaux for available resources necessitate the re­ open and operate the ACRF. The ACRF duction of $50.2 million, which is to be opening is scheduled to take place in the taken from categories other than research spring of 1981. project grant funds. With the FY 1982 budget, which was transmitted to the Congress Jan. 15, the The remaining $76 million increase is to President submitted a proposal for rescis­ be used for continuing a stable funding sion of $50.2 million from the $3,616,447,000 level for 5,000 new research project grants level for NIH contained in the 1981 Con­ and for providing 10,500 research tinuing Resolution, which has exceeded the traineeship awards in FY 1981.

1982 CONGRESSIONAL JUSTIFICATIONS (Carter) Summary by Appropriation (Budget authority in thousands) Dr. Tully, invited to deliver a lecture prior to the 1980 1981 1982 presentation of his honorary degree, chose as Comparable Comparable' Request Change his topic, Mycoplasmas and Their Developing Role in Neurological Disease. NCI ...... $ 999,191 $ 996,347 $1,041,761 $ 45,414 Dr. Joseph Tully of N IAID's Laboratory of NHLBI ...... 527,663 553,456 596,454 42,998 Infectious Diseases was recently awarded NIDR ...... 68,428 72,033 76,447 4,414 an honorary doctor honoris causa degree by NIAMDD ...... 341,415 371,623 390,536 18,913 the University of Bordeaux II in recognition NINCDS ...... 242,175 253,962 281,181 27,219 of his outstanding work on mycoplasmas NIAID ...... 215,573 234,761 248,179 13,418 and his long-term collaboration with the NIGMS ...... 312,479 336,155 362,035 25,880 university. Bordeaux II is the university's NICHD ...... 209,059 221,958 235,849 13,891 medical school. NEI ...... 113,031 118,555 134,401 15,846 Much of his collaboration with the uni­ versity involved scientific exchanges with NIEHS ...... 83,896 95,212 112,498 17,286 NIAID's mycoplasma program and the uni­ NIA ...... 70,063 76,319 86,099 9,780 versity's laboratory of cellular and molecu­ ORR ...... 169,228 174,126 192,111 17,985 lar biology, directed by Professor Joseph ...... • • FIC ...... 8,987 9,291 9,612 321 Bove. Dr. Tully was also cited for other contri­ butions, including his efforts as program Subtotal, IRD's ...... 3,361,188 3,513,798 3,767,163 253,365 chairman of the 1st International Congress NLM ...... 43,979 45,482 47,692 2,210 ...... on Mycoplasmas of Plants, Animal_s, Man, OD ...... 20,248 22,566 23,524 958 and Insects held in Bordeaux in 1974. Buildings & Facilities ...... 3,250 11,750 10,310 -1,440 As a result of this congress, a new Inter­ national Research Program on Comparative Mycoplasmology was established with Dr. 3,428,665 3,593,596 3,848,689 255,093 Tully elected as its first chairman. He joined the National Institute of Allergy 'Includes proposed supplemental for 70% pay costs ($27,522) and proposed rescission and Infectious Diseases in 1962 as a re­ (-$50,200). search microbiologist in the Laboratory of Bacterial Diseases. D Four New Members Named to DRR Advisory Council

Four new members have been appointed Dr. Van Citters received a research career Dr. Hess has recently completed terms on to the National Advisory Research Re­ development award from PHS in 1962 and the General Clinical Research Centers and sources Council. also participated as an exchange scientist in the Biomedical Research Support Program They are: Ors. Joseph A. Abbott, clinical the joint US-USSR Scientific Exchange review committees, and is currently a professor and chief of the cardiac section of Agreement. member of the ORR CLINFO Advisory the University of California, San Francisco Committee. His career activities at the University of medical teaching program, Fresno, Calif.; Born in Weona, Ark., Dr. Purdy has gen­ Washington included cardiovascular re­ Robert L. Van Citters, dean of the University eral background experience in business, fi­ search at the School of Medicine and pri­ of Washington School of Medicine; Evelyn nance, economics, program administration mate research at DRR's Regional Primate V. Hess, professor of medicine and director and educational management. Research Center. He is a professor of of the division of immunology at the Uni­ He was named to physiology and biophysics, and also a pro­ Who's Who in American versity of Cincinnati College of Medicine; in 1962, listed in fessor of medicine. Colleges Outstanding and Paul W. Purdy, vice president for fiscal Young Men in America in 1969 and 1973, affairs at Jackson State University. Originally from Dublin, Ireland, Dr. Hess and also in Outstanding Educators of Specializing in cardiology, Dr. Abbott has joined the staff of the University of Cincin­ America in 1973. been a consultant for the National Science nati College of Medicine in 1964 as as­ Dr. Purdy has served as an officer and on Foundation. He is a member of the San sociate professor and director of the divi­ the board of several organizations. Francisco, Central Valley, and Alameda sion of immunology, and became the He has also served as a consultant for the Heart Associations. McDonald professor of medicine in 1969. Sickle Cell Disease Branch of NHLBI. D

January 21, 1981 The NIH Record Page 11 New Egg Cell Transplant Technique $1.2 Million for Basic Cancer Research Used in Mammals for 1st Time Given to 2 Scientists by Business Foundation Experiments involving the transfer of the Anfinsen, National Institute of Arthritis, nucleus from a mouse embryo cell to an Metabolism, and Digestive Diseases, who unrelated enucleated mouse egg cell have won the Nobel Prize in Chemistry in 1972; been carried out by Dr. Karl lllmensee of Daniel Nathans of Johns Hopkins Univer­ the University of Geneva, Switzerland, and sity, who was awarded a Nobel Prize in Dr. Peter Hoppe of Jackson Laboratories, Physiology or Medicine in 1978; George Bar Harbor, Me. Emil Palade of Yale University, who was alsc Their research was supported in part by awarded the Nobel Prize in Physiology or NIH. Medicine in 1974; Van Rensselaer Potter, This was the first successful application of professor of oncology at the University of the technique to mammals and resulted in Wisconsin; Harry Smith, Jr., chairman of the production of three healthy mice. Dr. Leder Dr. Erikson the department of biostatistics at Mount Each of the three mice appeared to be Sinai School of Medicine, and Lewis genetically identical to the mouse donating Two scientists were recently awarded $1.2 Thomas, chancellor of Memorial Sloan­ the nucleus in that case, but unrelated million to conduct basic biological research Kettering Cancer Center. genetically to the egg donor or to the foster on the fundamental cause of cancer by a Although Dr. Leder is not generally con­ mother in whose uterus the egg was im­ unique foundation that has solicited dona­ sidered a cancer researcher, his work in planted. tions from some of the Nation's largest cor­ genetics is well recognized as being "so Similar experiments have been done in porations. fundamental and so broad that most any­ many laboratories over the past 30 years with amphibians (frogs and toads), but the The two grants, $600,000 each, will be thing he does has a bearing on cancer re­ recently announced nuclear transplantation used over the next 5 years to support the search," said Dr. Anfinsen, explaining the was technically much more difficult because work of Drs. Philip Leder and Raymond L. importance of genetics in understanding mouse eggs are about 3,000 times smaller Erikson. Dr. Leder was recently appointed the causes of cancer. than frog eggs. chairman of the department of genetics and Dr. Erikson Is NCI Grantee Some media reports tend to equate the professor of genetics at Harvard Medical reported research to the popular notion of School. He is on leave of absence from his Currently Dr. Raymond L. Erikson holds cloning which involves the copying of adult position as chief of the Laboratory of three National Cancer Institute grants re­ animals. Experts have pointed out, how­ Molecular Genetics, National Institute of lating to the biosynthesis of viral ever, that all successful nuclear transplan­ Child Health and Human Development. Dr. transformation-specific antigens of the tations to date, including the mouse study, Erikson is professor of pathology at the avian RNA sarcoma virus, and a grant for a involved an embryo, and not an adult University of Colorado, a National Cancer program in developmental histology of donor. Institute grantee. cancer structure and replication of oncor­ It has not been possible, and may never Harry Williams Creates Fund naviruses. be, to produce an animal from the trans­ The American Business Cancer Research planted nucleus of an adult cell. The grants were the first to be made by Foundation plans to make similar grants The reported advance, however, gives next year, noted Mr. Williams. He success­ the American Business Cancer Research scientists an important new technique with Foundation, a 2-year-old fund created by fully campaigned for donations among the which to study nuclear-cytoplasmic interac­ top echelons of business by stressing that it Harry D. Williams 11, a retired residential tions in embryo development and differ­ was in the best interest for the future of housing developer from Connecticut. entation, which may yield information valu­ American corporations to learn about what Mr. Williams became interested in un­ able in understanding the cause of birth makes cancer occur. □ derstanding cancer after his wife, Jayne, de­ defects. "He has convinced industry, the drug and veloped cancer and was treated at Yale. His chemical companies that it is important to study of cancer funding led him to conclude know the difference between a cancerous that a private foundation could keep cell and a normal cell," said Dr. Anfinsen, bureaucracy and report writing to a describing Mr. Williams efforts, and "in­ minimum and give research money directly dustry has gone along with it." to investigators recognized for their ongo­ The foundation's corporate sponsors in­ ing fundamental research. clude: the Diamond Shamrock Corporation, "The grants are in recognition of their the Dow Chemical Company, the Exxon already demonstrated excellence in re­ Corporation, the Mobil Corporation, the search," said Mr. Williams when he an­ Monsanto Company, the Olin Corporation, nounced the grants. Procter & Gamble Company, the Schering­ Drs. Leder and Erikson were selected Plough Corporation, the Stauffer Chemical from among 20 scientists by a scientific ad­ Company, the Union Carbide Corporation, visory panel composed of some of the Na­ Capital Cities Communications Inc., and tion's leading basic biological researchers such trusts as the H. Smith Richardson recruited by Mr. Williams. Charitable Trust and the Educational Foun­

The panel members are: Drs. Christian B. dation of America. □ Recombinant DNA Committee Approves Certain Changes Philip D. Amoruso was recently named execu­ tive officer of the National Cancer Institute, The NIH Recombinant DNA Advisory allow certain additional experiments with where he will be responsible for evaluating Committee (RAC) held its 21st meeting on foot and mouth disease virus; a proposed NCl's programs. He returns to NCI from his Jan. 8 and 9. change in the NIH Guidelines to lower post as executive officer of NLM. Previously, he The NIH Recombinant DNA Risk Assess­ containment for experiments with non­ served with NCI for 10 years in various manage­ ment Program and the recent meeting of pathogenic prokaryotes and lower rial positions, including more than 4 years as chairpersons from the Institutional eukaryotes; and proposed changes in pro­ administrative officer for the Division of Cancer Biosafety Committees were discussed. cedures for review of minor modifications Treatment. The RAC recommended approval of a of previously approved large-scale experi­

number of items including: a request to ments. □ *U.S. GOVERNMENT PRINTING OFFICE: 1980-341-134/109 Page 12 The NIH Record January 21, 1981